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Overcoming Resistance To Sg-Aris In Castration-Resistant Prostate Cancer, Chaohao Li Jan 2022

Overcoming Resistance To Sg-Aris In Castration-Resistant Prostate Cancer, Chaohao Li

Theses and Dissertations--Toxicology and Cancer Biology

Prostate cancer (PCa) ranks as the most diagnosed type of cancer and the second leading cause of death in men. Androgen receptor (AR) signaling plays a pivotal function in promoting the survival and progression of PCa. Therefore, medication for PCa mainly focuses on the inhibition of AR pathway, which is termed androgen deprivation therapy (ADT). However, the disease eventually progresses and develops to a lethal stage called castration-resistant prostate cancer (CRPC) that is characterized by resistance to canonical ADT. To deal with this situation, several second-generation AR inhibitors (SG-ARIs) have been created that have better efficacy against AR, including Enzalutamide …

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Stay-At-Home Fathers: What Is Their Life Really Like? An Intimate Portrayal, Christi Ann Hosking Jan 2022

Stay-At-Home Fathers: What Is Their Life Really Like? An Intimate Portrayal, Christi Ann Hosking

Graduate Theses/Dissertations

Reinforced by years of gender stereotypes is modern societies’ definition of masculinity, which has long been characterized by breadwinning and providing. Current literature has observed the growing trend which finds an increasing number of men engaged in the role of caregiver and the dynamic change in the home-work balance. Only a few studies looked at what life is like for a stay-at-home father and even fewer have allowed these fathers a unique voice for sharing their story. The purpose of this study was to gain an in-depth understanding of what day to day life was really like as a stay-at-home …

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The Role Of The Host Factor Sptbn1 In Hiv-1 Infection Of Microglial Cells, Marc Gordon Havlicek Jan 2022

The Role Of The Host Factor Sptbn1 In Hiv-1 Infection Of Microglial Cells, Marc Gordon Havlicek

Graduate Theses/Dissertations

HIV-1 is the etiological agent that cause AIDS. Since the 1980’s when HIV-1 was discovered, much has been discovered, however a cure for HIV-1 has eluded researchers. Effective therapeutics do exist but can have adverse side effects including HAND/HAD which leads to neurodegeneration in patients regardless of viral suppression. One area of research that holds the possibility of discovering new viral targets and therapeutics is host factor interaction within the replication process. One host factor that can cause a decrease in HIV-1 infectivity is SPTBN1. SPTBN1 is a cytoskeletal protein that was shown to bind to the capsid and nucleocapsid …

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Overcoming The Odds: The Effects Of The Relationship Between Childhood Adversity, Lifetime Trauma, And Resiliency On Empathy And Conscientiousness, Victoria West Staples Jan 2022

Overcoming The Odds: The Effects Of The Relationship Between Childhood Adversity, Lifetime Trauma, And Resiliency On Empathy And Conscientiousness, Victoria West Staples

Graduate Theses/Dissertations

This research sought to understand the connection between trauma and the development of resiliency while examining the effects of that relationship on empathy and conscientiousness. Specifically, this study was created to answer four main questions: (1) Does early childhood adversity predict later life trauma? (2) Does childhood adversity and cumulative lifetime traumatic experiences impact the development of resiliency and its subconstructs (i.e., interpersonal resiliency and intrapersonal resiliency)? (3) Is empathy impacted by the presence of resiliency, specifically examining its effect on cognitive and affective empathy (using questionnaires and galvanic skin response)? (4) And is conscientiousness related to resiliency subconstructs? There …

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Tissue And Sex-Specific Rna Editing During Induced Acute Inflammation, Claire E. Nichols Jan 2022

Tissue And Sex-Specific Rna Editing During Induced Acute Inflammation, Claire E. Nichols

Graduate Theses/Dissertations

A-to-I RNA editing is a process where select adenosine (A) nucleotides are deaminated by an editing enzyme, ADAR, to become inosines (I) in RNA transcripts. RNA editing can affect the sequence of the encoded protein and the regulation of the RNA. ADAR1 also plays a role in regulating innate immunity and its expression is upregulated during inflammation. Current data on the effects of increasing ADAR1 on RNA editing is limited, and most studies are completed only in male animals. We are interested in expanding RNA editing data to include female animals. Lipopolysaccharide (LPS) was used to induce acute inflammation and …

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Characterization Of Nanoparticles Using Inductively-Coupled Plasma Mass Spectrometry, Jabez D. Campbell Jan 2022

Characterization Of Nanoparticles Using Inductively-Coupled Plasma Mass Spectrometry, Jabez D. Campbell

Graduate Theses/Dissertations

Nanomaterials are a relatively new class of materials that have many applications which span a wide host of fields from medical products to consumer products. The possible compositions and forms of nanomaterials are just as varied as the applications. Therefore, a versatile characterization method is needed for researchers and regulators alike to ensure nanomaterials are properly used. Single Particle Inductively Coupled Plasma Mass Spectrometry (SP-ICP-MS) is a functional method that could fill the characterization need in the nanomaterial research field. Using data from both SP-ICP-MS tests and data from literature established characterization methods, the viability of making SP-ICP-MS the standard …

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Elucidating The Role Of Hemodynamic Force In Regulating The Attachment Of Vascular Smooth Muscle Cells (Vsmcs) To Maturing Vessels During Mouse Embryonic Development, Israt Jahan Jan 2022

Elucidating The Role Of Hemodynamic Force In Regulating The Attachment Of Vascular Smooth Muscle Cells (Vsmcs) To Maturing Vessels During Mouse Embryonic Development, Israt Jahan

Graduate Theses/Dissertations

Blood vessel maturation is characterized by the recruitment and attachment of vascular smooth muscle cells (vSMCs) around immature blood vessels, which ultimately form the tunica media. Improper maturation can lead to vascular birth defects ranging from minor birthmarks to lethal brain aneurysms. Previously, our lab demonstrated that hemodynamic force plays an important role to regulate vSMCs recruitment from neighboring low-flow to high-flow vessels followed by the attachment of these vSMCs to the high-flow vessels. To understand the reason for the preferred attachment of vSMCs to high-flow vessels, instead of low-flow vessels, I hypothesize that hemodynamic force modulates the expression of …

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Utilizing Virtual Reality Goggles During Pediatric Laceration Repairs To Reduce Perceived Pain In Pediatric Patients, Emily C. Bozzer Jan 2022

Utilizing Virtual Reality Goggles During Pediatric Laceration Repairs To Reduce Perceived Pain In Pediatric Patients, Emily C. Bozzer

Graduate Theses/Dissertations

In pediatric emergency departments, several providers assess pediatric patients in need a laceration repair, require procedural sedation in order to ensure compliance and complete the laceration repair. This study explored one safe alternative to procedural sedation during pediatric laceration repairs by assessing what pain scores pediatric patients report when undergoing a laceration repair utilizing virtual reality goggles. Pediatric patients ages 6-17 years old perceived pain scores utilizing FACES pain scale was documented. This study found a majority of patients reported lower pain scores during the laceration repair in comparison to their baseline pain score.

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Identification Of A Novel Protein Interaction That Elucidates The Mechanism Of Idiopathic Recurrent Miscarriages In Women With Nlrp2 Mutations, Nayeon Son Jan 2022

Identification Of A Novel Protein Interaction That Elucidates The Mechanism Of Idiopathic Recurrent Miscarriages In Women With Nlrp2 Mutations, Nayeon Son

Graduate Theses/Dissertations

The protein NOD-Like receptor pyrin domain containing 2 (NLRP2) is one member of a larger family of protein receptors that plays an important role in our innate immune system. In humans, the NLR family consists of 22 proteins. However, only about a half of NLRs’ functions are known, but many are pro-inflammatory, causing inflammation. NLRP2 has been identified to be a maternal effect gene regulating early embryo development in idiopathic recurrent miscarriages. In previous studies, mutations in the NLRP2 gene resulted in genetic maternal imprinting disorders due to NLRP2 regulating DNA methylation. However, the exact mechanisms involved in recurrent miscarriages …

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Mining-Contaminated Sediment And Metal Storage In Channel Deposits In Turkey Creek, Tri-State Mining District, Missouri And Kansas, Max Quinn Hillermann Jan 2022

Mining-Contaminated Sediment And Metal Storage In Channel Deposits In Turkey Creek, Tri-State Mining District, Missouri And Kansas, Max Quinn Hillermann

Graduate Theses/Dissertations

The Joplin subdistrict, within the Tri-State Mining District (TSMD), was a major producer of lead (Pb) and zinc (Zn) ore between the 1880s to 1920s. Metalliferous mining wastes are still stored in the channel deposits of local streams raising environmental and health concerns. This study quantifies the volume, sediment size, and metal concentrations in channel bed, bar, bench, and chute deposits to quantify the spatial variability of contaminated sediment storage in Turkey Creek (119 km2). Sample reaches (n=14) contained metal concentrations elevated above the Tri-State Mining District specific probable effects concentration at every site with mean concentrations in …

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Synthesis And Characterization Of Chitosan Derivatives Intended For Gene Delivery Applications, Alex M. Mcmullen Jan 2022

Synthesis And Characterization Of Chitosan Derivatives Intended For Gene Delivery Applications, Alex M. Mcmullen

Graduate Theses/Dissertations

Chitosan has been studied as a non-viral vector capable of efficient gene delivery due to its favorable properties such as biodegradability, biocompatibility, and is non-toxic to mammalian cells. Incorporating electrostatic interactions in non-viral vectors enhance the vector permeability. This work focuses on two parts. Firstly, cationic chitosan derivatives were synthesized using quarternary ammonium and phosphonium groups. This was achieved by coupling carboxylic acid ligands with these quarternary groups to chitosan through an amide bond. The carboxylic acid ligands were synthesized from 4-methylbenzoic acid and either triethyl phosphine or triethyl amine. The ligand was then attached to chitosan through an amide …

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Development Of Peg-B-Pla Based Micelles For Neutralization Of A Toxic Peptide, Giselle Campos Jan 2022

Development Of Peg-B-Pla Based Micelles For Neutralization Of A Toxic Peptide, Giselle Campos

Graduate Theses/Dissertations

I herein report the preparation and characterization of PEG-b-PLA block copolymer micelles and PEG-b-PLA/PLA mixed micelles as potential “plastic antidotes” for a toxic peptide, melittin. PEG-b-PLA micelles have been used in a number of biomedical applications for their biodegradability and biocompatibility. Along these lines, I investigated the colloidal stability and the peptide absorption properties of PEG-b-PLA/PLA mixed micelles. A series of PEG-b-PLA block copolymer micelles and PEG-b-PLA/PLA mixed micelles were prepared, and their colloidal stability was studied. The hydrodynamic diameters of stable micelles were determined by using Dynamic …

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Effects Of Sex And Reproductive Condition On Behavior Of Southern Red-Backed Salamanders: Activity, Agonistic Behavior And Escape Velocity, Megan N. Mosier Jan 2022

Effects Of Sex And Reproductive Condition On Behavior Of Southern Red-Backed Salamanders: Activity, Agonistic Behavior And Escape Velocity, Megan N. Mosier

Graduate Theses/Dissertations

Producing and carrying eggs is energetically costly and therefore can affect behavior. Female Southern Red-backed Salamanders (Plethodon serratus) in the Ozarks reproduce biennially, and so during the reproductive season some females are gravid and some are non-gravid. In this study, we compared the exploratory and aggressive behaviors of gravid females, non-gravid females, and males, as well as the escape velocities of each sex class. In exploratory trials, sex did not affect distance travelled, but gravid females and males showed shorter latencies to move than non-gravid females during the winter. During the aggression trials, individuals were subjected to a …

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Synthesis Of Novel Nio/Comn2o4 Heterostructured Nanoparticles And The Effects Of Variable Size And Metal Concentrations On Their Magnetic And Surface Chemical Properties, Farhan Ishrak Jan 2022

Synthesis Of Novel Nio/Comn2o4 Heterostructured Nanoparticles And The Effects Of Variable Size And Metal Concentrations On Their Magnetic And Surface Chemical Properties, Farhan Ishrak

Graduate Theses/Dissertations

I studied the effect of core size and metal concentration on the structural, morphological, and magnetic properties of NiO-based magnetic heterostructured nanocrystals (HNCs) generated hydrothermally. The NiO nanocrystals were created by a thermal decomposition technique, while the surrounding Mn and Co-based phases were created through a hydrothermal procedure, with core diameters ranging from 9.31 nm to 24.51 nm and total metal concentrations of 0.05 M and 0.08 M. The resulting inverted AFM-FiM NiO/CoMn2O4 bimagnetic systems make up the heterostructured nanocrystals. The magnetic HNCs were thoroughly characterized using XRD, SEM-EDX, TEM, PPMS magnetometry, and XPS analysis. Investigations into the structure of …

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Role Of Cyclophilin A And Trim5Α In Hiv-1 Infection And Capsid Uncoating, Emma Lk Wise Jan 2022

Role Of Cyclophilin A And Trim5Α In Hiv-1 Infection And Capsid Uncoating, Emma Lk Wise

Graduate Theses/Dissertations

Microglial cells are immune cells that protect the central nervous system and are subject to HIV- 1 infection. HIV-1 infection of these cells can lead to HIV Associated Neurocognitive Disorders (HAND). Since HIV-1 only codes for 15 different proteins, the virus also uses cellular factors, like Cyclophilin A (CypA), to assist in viral replication. The cell also has antiretroviral restriction factors, like tripartite motif-containing protein 5 (TRIM5α), to protect against infection. The goal of this project is to investigate the role of CypA in the early steps of HIV-1 replication and TRIM5α restriction in microglial cells. I hypothesize that CypA …

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Reducing Family Risk Factors Caused By Poverty Through Family Support Services, Aaliyah C. Williams Jan 2022

Reducing Family Risk Factors Caused By Poverty Through Family Support Services, Aaliyah C. Williams

Graduate Theses/Dissertations

This study aims to determine whether preventative measures are effective if implemented while a family is in crisis, through Family Support Services (FSS), to alleviate Risk Factors, prevent family separation and ensure prolonged family stability, instead of as services to reunify a family that already separated due to a lack of resources. This study examined the Poverty Related Risk Factors of Homelessness, Single Parenthood, and Unemployment as Risk Factors that families enrolled in Ozarks Area Community Action Corporation (OACAC) Head Start experience as negative influences on child development and Family Unity and analyzed OACAC Head Start’s implementation of FSS as …

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Effectiveness Of Stabilized Hypochlorous Acid In Acute Peritonitis Treatment: A Murine Surgical Study, Benjamin Michael Pomeroy Jan 2022

Effectiveness Of Stabilized Hypochlorous Acid In Acute Peritonitis Treatment: A Murine Surgical Study, Benjamin Michael Pomeroy

Graduate Theses/Dissertations

Peritonitis is an inflammatory condition affecting the mesothelial cells that line the peritoneal cavity and is commonly induced by bowel perforations. This medical emergency is treated through antibiotic therapy and surgical intervention followed by tissue irrigation (lavage). Acute treatments aim to remove the bacterial burden, however recurring peritoneal infections occur at high rates and contribute to patient morbidity. These recurring infections are likely due to the inability of lavage solutions to remove the entire massive intra-abdominal bacterial load due to intestinal perforation. Numerous antiseptic solutions and antibiotic additives have been evaluated in their ability to improve source control by abdominal …

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Intercropping Grain Sorghum Into Established Rhizoma Peanut: Greenhouse And Field Studies, Erika Hm Cooperman Jan 2022

Intercropping Grain Sorghum Into Established Rhizoma Peanut: Greenhouse And Field Studies, Erika Hm Cooperman

Graduate Theses/Dissertations

Land degradation and urbanization are among the top factors pushing the Kenyan Maasai community into an unstable future, with food insecurity and poverty amidst the most fragile components. Implementing conservation agricultural techniques into the Maasai nomadic lifestyle could potentially lead to a diversification of finances and food security. Intercropping is one technique of conservation agriculture that could provide the Maasai both. The main objective of this study is to evaluate the effects of creating an intercropped environment between rhizoma peanut and grain sorghum. A greenhouse study was conducted from late 2020 to 2021 in an effort to investigate the effects …

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On The Synthesis And Characterization Of Bimagnetic Coo/Nife2o4 Heterostructured Nanoparticles, Muhammad Sharif Uddin Jan 2022

On The Synthesis And Characterization Of Bimagnetic Coo/Nife2o4 Heterostructured Nanoparticles, Muhammad Sharif Uddin

Graduate Theses/Dissertations

Bimagnetic nanoparticles show promise for applications in energy efficient magnetic storage media and magnetic device applications. The magnetic properties, including the exchange bias of nanostructured materials can be tuned by variation of the size, composition, and morphology of the core vs overlayer of the nanoparticles (NPs). The purpose of this study is to investigate the optimal synthesis routes, structure and magnetic properties of novel CoO/NiFe2O4 heterostructured nanocrystals (HNCs). In this work, I aim to examine how the size impacts the exchange bias, coercivity and other magnetic properties of the CoO/NiFe2O4 HNCs. The nanoparticles with sizes ranging from 10 nm to …

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Evaluating Exploitation Of White Crappie And Black Crappie In Three Southeast Kansas Reservoirs, Danci Lee Johnston Jan 2022

Evaluating Exploitation Of White Crappie And Black Crappie In Three Southeast Kansas Reservoirs, Danci Lee Johnston

Graduate Theses/Dissertations

Populations of white crappie Pomoxis annularis and black crappie P. nigromaculatus were studied in three southeast Kansas reservoirs to assess exploitation and determine if current regulations were conducive for sustainable populations. Trap nets were used to sample crappie in Elk City Reservoir, Big Hill Reservoir, and Parsons City Lake. Crappie with length 210 mm and greater were tagged with FloyFD-94 tags that served as entries into a drawing for a US$300-valued reward to encourage tag reporting. Harvest and angler demographic information were collected when tags were reported. Postcard surveys and motion-sensed cameras were used in conjunction to estimate angler effort …

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Effects Of Natural Products On Inflammation, Riley Ann Nadler Jan 2022

Effects Of Natural Products On Inflammation, Riley Ann Nadler

Graduate Theses/Dissertations

Chronic inflammation is characterized by infiltration of inflammatory cells such as macrophages and lymphocytes into the tissue where they produce inflammatory cytokines that contribute to tissue damage. Worldwide, 3 out of 5 people die due to chronic inflammatory diseases like cardiovascular diseases, obesity, diabetes, and cancer. Since it is well-documented that diet and metabolism are key mediators of inflammation, I investigated the effects of dietary lectins on inflammatory cytokine production and the ability of sodium pyruvate, a metabolite, to decrease inflammation. In chapter 1, I examined the effect that lectins from either Triticum vulgaris (common wheat) or Phaseolus vulgaris (common …

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The Role Of Actin Associated Sptbn1 Host Factor In Hiv-1 Infection In Microglial Cells, Hannah Matheney Jan 2022

The Role Of Actin Associated Sptbn1 Host Factor In Hiv-1 Infection In Microglial Cells, Hannah Matheney

Graduate Theses/Dissertations

Human immunodeficiency virus (HIV) is a chronic illness affecting more than 32.7 million individuals worldwide. The virus infects immune cells, weakening the immune system overtime eventually leading to acquired immunodeficiency syndrome (AIDS) if left untreated. Infection starts with a fusion step, followed by uncoating of the HIV capsid once in the cytoplasm of the cell. HIV uses host cell proteins to complete the infection process, like the actin associated factor, SPTBN1. The Hulme lab has previously shown that SPTBN1 knockdown by siRNA in microglial cells decreased HIV infection and delayed uncoating of HIV. Because fusion is prior to uncoating, it …

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Speaker Encoding For Zero-Shot Speech Synthesis, Tristin W. Cory Jan 2022

Speaker Encoding For Zero-Shot Speech Synthesis, Tristin W. Cory

Graduate Theses/Dissertations

Spoken communication, for many, is an essential part of everyday life. Some individuals can lose or not be born with the ability to speak. To function on a day-to-day basis, these individuals find other ways of communication. Adaptive speech synthesis is one of those ways. It recreates a user’s previous voice or creates a voice that blends with their regional dialect. Current adaptive speech synthesis techniques that achieve human-like speech require thirty minutes, to a few hours of high-quality audio recordings of a target speaker. This amount of recorded audio is not commonly possessed by people in need of a …

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Testing The Impact Of A Silencing Suppressor On Infectivity Of Grapevine Vein Clearing Virus Infectious Clone In Nicotiana Benthamiana, Wen Zhao Jan 2022

Testing The Impact Of A Silencing Suppressor On Infectivity Of Grapevine Vein Clearing Virus Infectious Clone In Nicotiana Benthamiana, Wen Zhao

Graduate Theses/Dissertations

Grapevine vein clearing virus (GVCV), the first DNA virus of the Badnavirus genus discovered in grapevines, is closely associated with grapevine vein-clearing disease. Through earlier research, Koch's postulates were partially met: GVCV was in all diseased plants; GVCV was introduced into a healthy grapevine through grafting and by aphids and caused the disease. However, more shreds of evidence are required to fulfill the last postulate, the same virus must be reisolated from the inoculated diseased grapevine (1). A full-length infectious clone of GVCV was previously constructed to provide evidence; however, its infectivity was not consistent. Therefore, the goal …

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Emotion Validating Language Regarding Negative Emotions In The Classroom Differing By Gender And Emotion Type, Tea Rose Pankey Jan 2022

Emotion Validating Language Regarding Negative Emotions In The Classroom Differing By Gender And Emotion Type, Tea Rose Pankey

Graduate Theses/Dissertations

This study examined teachers’ emotion validating language regarding negative emotion in early childhood classrooms. By analyzing teachers’ emotion language differing by gender, the research highlights the gendered socialization of emotional expression, especially regarding negative emotions, in early childhood contexts. In toddler and preschool classrooms, 28 teachers were video recorded during 4 thirty-minute sessions of free play time. Videos were coded for teachers’ emotion language regarding negative emotions with attention to the gender of the child to whom the language was spoken. Results indicate that teachers validate negative emotions more to girls than to boys. This aligns with previous research that …

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Fair Allocation Of Scarce Therapies For Coronavirus Disease 2019 (Covid-19), Govind Persad, Monica E. Peek, Seema K. Shah Jan 2022

Fair Allocation Of Scarce Therapies For Coronavirus Disease 2019 (Covid-19), Govind Persad, Monica E. Peek, Seema K. Shah

Publications

The US Food and Drug Administration (FDA) has issued emergency use authorizations (EUAs) for monoclonal antibodies (mAbs) for nonhospitalized patients with mild or moderate coronavirus disease 2019 (COVID-19) disease and for individuals exposed to COVID-19 as postexposure prophylaxis. EUAs for oral antiviral drugs have also been issued. Due to increased demand because of the Delta variant, the federal government resumed control over the supply and asked states to ration doses. As future variants (e.g., the Omicron variant) emerge, further rationing may be required. We identify relevant ethical principles (i.e., benefiting people and preventing harm, equal concern, and mitigating health inequities) …

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Deep Features To Analyze Pulmonary Abnormalities In Chest X-Rays Due To Covid-19, Supriti Ghosh Jan 2022

Deep Features To Analyze Pulmonary Abnormalities In Chest X-Rays Due To Covid-19, Supriti Ghosh

Dissertations and Theses

Artificial Intelligence (AI) has contributed a lot since the beginning. Healthcare is no exception. Detecting anomaly/abnormality in (bio)medical image is crucial. In this thesis, we aim at detecting/screening pulmonary abnormalities due to Covid-19 in chest X-rays using deep features. We study CheXNet, DenseNet169, ResNet50 and VggNet16 to analyze CXRs to detect the evidence of Covid-19 in this research. CheXNet was primarily designed for radiologist-level pneumonia detection in Chest X-rays (CXRs). We created a benchmark dataset size of 4,716 CXRs (2,358 Covid-19 positive cases and 2,358 non-Covid cases (Healthy and Pneumonia cases)) and with k(=5) fold cross-validation technique, using the DenseNet, …

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Examining Phenotypes Of Hfq And Minc Knockout Mutants Generated Through Phage Transduction, Kate Donaldson Jan 2022

Examining Phenotypes Of Hfq And Minc Knockout Mutants Generated Through Phage Transduction, Kate Donaldson

A with Honors Projects

No abstract provided.

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Sex-Related Differences And Gender-Related Disparities In Adhd Development And Diagnosis: Applying The Biopsychosocial Model, Hannah Moore Jan 2022

Sex-Related Differences And Gender-Related Disparities In Adhd Development And Diagnosis: Applying The Biopsychosocial Model, Hannah Moore

A with Honors Projects

No abstract provided.

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The Benefits Of Offering Classroom Piano Lessons As Part Of The Curriculum In Public Elementary School, Denise Cheeks Mundy Jan 2022

The Benefits Of Offering Classroom Piano Lessons As Part Of The Curriculum In Public Elementary School, Denise Cheeks Mundy

Masters Theses

The purpose of this study is to determine the potential benefits of offering classroom piano lessons as part of the curriculum in public elementary schools. The research reviews the educational, neurological, and cultural potential benefits a child may receive if they study the piano. Further study examines the availability for teachers to receive training in teaching group piano, the methods of setting up a piano classroom, and materials needed for such a program in the school system. Records of the history of group lessons showed that this method of teaching has had periods of success and periods of decline in …

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