Digital Commons Network^™

Developing A Flapping Gear System For Butterfly-Inspired Motion, Frederick Schulze, Chang-Kwon Kang

AIAA Southeastern Regional Student Conference

Bioinspired flapping-wing drones have the potential to revolutionize data collection techniques with increased versatility and performance over existing rotary and fixed-wing drone types. Their capability for increased power efficiency is demonstrated in the long-range migration of Monarch butterflies. However, the wing motion is more complicated, resulting in three-dimensional wing kinematics. To better understand the performance of these wings, a flapping wing gear system is developed to reproduce the flapping motion of a monarch butterfly. The mechanism consists of a two-stage gear reduction and a 4-bar linkage to convert rotary motion to flapping motion. A dynamic analysis performed on the proposed …

Unh/Noaa Joint Hydrographic Center 2021 Performance And Progress Report, Larry A. Mayer, Noaa-Unh Joint Hydrographic Center (Jhc/Ccom)

Progress Reports

Reporting Period: 01/01/2021–12/31/2021

Andragogy: The Common Thread In The Teaching Of Adults In Colleges Of Education, Criminal Justice, And Health Management, Grant J. Shostak, Larry Acker, Vanessa Vandergraaf

Faculty Scholarship

The Covid-19 pandemic has brought dramatic changes to higher education. Students and educators face challenges never anticipated, including switching classes from on-ground to online and back again, mental fatigue, stress, and burnout. Faculty across disciplines may turn to Andragogy to best teach college students to inform their teaching practices. This paper demonstrates how professors from education, criminal justice, and healthcare management have used andragogical techniques in their classrooms.

The Role Of The Accessory Gene Regulator Operon In Biofilm Formation By Staphylococcus Aureus, Sarah C. Jordan

Pharmaceutical Sciences ETDs

Staphylococcus aureus is a pathogenic bacteria that causes significant morbidity and mortality. As antibiotic resistance by S. aureus continues to be a serious concern, developing novel drug therapies to combat these infections is vital. Quorum sensing inhibitors (QSI) dampen S. aureus virulence and facilitate clearance by the host immune system by blocking quorum sensing signaling that promotes upregulation of the accessory gene regulator (agr) operon. While QSIs have shown therapeutic promise in mouse models of S. aureus infection, their further development has been hampered by the suggestion that agr inhibition promotes biofilm formation. In these studies, we investigated the relationship …

University Of Dayton Undergraduate Biology Researcher Awarded Honorable Mention For Presentation At Midwest Drosophila Meeting, Allison Brace

College of Arts and Sciences Newsroom

University of Dayton senior Hannah Darnell was one of two undergraduate students selected to present research at the 2021 Midwest Drosophila Conference in October at Indiana University in Bloomington. She was awarded honorable mention for her presentation.

The Utah Statesman, January 31, 2022, Utah State University

The Utah Statesman

No abstract provided.

A Proposal For Paid Family Leave In Utah, Erin Wong

Student Works

When a woman gives birth, the arrival of that child will have a statistically significant negative impact on that woman’s employment, earning potential, health, and overall wellbeing. The arrival of a child has no statistically significant impact on men’s employment, earning potential, or overall health and wellbeing. The labor force experiences a drain of talent and productivity when mothers leave the market in large numbers after having a child. Many mothers who wish to remain the workforce after childbirth are faced with the impossible choice of their child’s health or their own job and earning potential. Many fathers or partners …

A Twist To The Kirby-Bauer Disk Diffusion Susceptibility Test: An Accessible Laboratory Experiment Comparing Haloferax Volcanii And Escherichia Coli Antibiotic Susceptibility To Highlight The Unique Cell Biology Of Archaea, Heather Schiller, Criston Young, Stefan Schulze, Manuela Tripepi, Mechthild Pohlschroder

College of Life Sciences Faculty Papers

Archaea, once thought to only live in extreme environments, are present in many ecosystems, including the human microbiome, and they play important roles ranging from nutrient cycling to bioremediation. Yet this domain is often overlooked in microbiology classes and rarely included in laboratory exercises. Excluding archaea from high school and undergraduate curricula prevents students from learning the uniqueness and importance of this domain. Here, we have modified a familiar and popular microbiology experiment-the Kirby-Bauer disk diffusion antibiotic susceptibility test-to include, together with the model bacterium Escherichia coli, the model archaeon Haloferax volcanii. Students will learn the differences and similarities between …

Zoonotic Pathogens From Illegally Traded Wildlife Justify Adopting The One Health Perspective In Disease Response, Marianne Allison G. Lee, Vinyl Joseph S. Valeza, Jonathan Patrick H. Yan, Ronald Allan L. Cruz

Biology Faculty Publications

Recent studies have described a direct relationship between the illegal wildlife trade (IWT) and the prevalence of zoonotic pathogens in human populations. In the Philippines, the Philippine Integrated Disease Surveillance and Response (PIDSR) framework outlines the monitoring, response, and management of disease outbreaks, but needs to be updated in the wake of zoonoses from IWT. Here, we identified zoonotic pathogens that may be introduced to human populations through the IWT, pinpointed potential outbreak hotspots, and provided recommendations on how to improve the Philippines’ public health response while considering One Health. Using seizure data from the Biodiversity Management Bureau (DENR-BMB) covering …

Unh/Noaa Joint Hydrographic Center 2021 Performance And Progress Report Executive Summary, Larry A. Mayer, Noaa-Unh Joint Hydrographic Center (Jhc/Ccom)

Progress Reports

Reporting Period: 01/01/2021–12/31/2021

Precarity And Motherhood In Philippine Trans Cinema, Mikee Inton-Campbell

Akda: The Asian Journal of Literature, Culture, Performance

In this short essay, I reflect on representations and themes in trans cinema in the Philippines. I examine the emerging and intersecting themes of precarity and motherhood in two recent films –Rod Singh’s Mamu and a Mother too (2018), and Isabel Sandoval’s Lingua Franca (2020). I look at how economic and social precarity tends to pervade the lives of trans women, and how transness itself becomes a form of precarity under the legal system’s lack of accommodation to trans rights. I also examine trans motherhood and make the argument that while it destabilizes biology as the root of motherhood, it …

Preliminaries And Editor's Introduction, Dinah Roma

Akda: The Asian Journal of Literature, Culture, Performance

No abstract provided.

Crow's Nest, January 31, 2022, Crow's Nest Staff

Crow's Nest

The January 31, 2022, issue of the Crow's Nest.

Decolonizing The Environment: Third World Approaches To The Planetary Crisis, Kishan Khoday

Indonesian Journal of International Law

The colonial process transformed the landscape of the Earth with devastating consequence for communities and ecosystems. It also set the foundations of the planetary crisis that we see today. Using a TWAIL approach, this article argues for the relevance of colonial and post-colonial analysis in combatting today’s planetary crisis and advancing a more effective form of global environmental governance. Today’s global order of multilateral agreements is increasingly under criticism, ineffective in combating the planetary crisis and in halting the disproportionate impact of ecological change experienced across the global South. A TWAIL lens helps to understand the root causes of today’s …

Offshore Spreading Of A Supercritical Plume Under Upwelling Wind Forcing: A Case Study Of The Winyah Bay Outflow, Alexander E. Yankovsky, Douglas Cahl, George Voulgaris

Faculty Publications

In this study, we present observations of the Winyah Bay (WB) plume (SC, United States) formed by high freshwater discharge and a moderate upwelling-favorable wind acting continuously for ∼1.5 days prior to the shipboard survey. If a similar wind forcing persists over a longer period, the plume turns upstream (against its natural propagation) and curves offshore forming a “filament” with minimal transverse spreading, as seen in numerous satellite images. The observed plume comprises a train of tidal sub-plumes undergoing rotational adjustment and being transported offshore by Ekman dynamics. The WB outflow is supercritical in terms of the interior Froude number. …

Technology Mergers And The Market For Corporate Control, Geoffrey A. Manne, Samuel Bowman, Dirk Auer

Missouri Law Review

Several high-profile academic articles and reports claim to have identified important gaps in current merger enforcement rules, particularly with respect to tech and pharma acquisitions involving nascent and potential competitors—so-called “killer acquisitions” and “kill zones.” As a result of these perceived deficiencies, scholars and enforcers have called for tougher rules, including the introduction of lower merger filing thresholds and substantive changes, such as the inversion of the burden of proof when authorities review mergers and acquisitions in the digital platform industry. Meanwhile, and seemingly in response to the increased political and advocacy pressures around the issue, U.S. antitrust enforcers have …

Conformational Flexibility And Local Frustration In The Functional States Of The Sars-Cov-2 Spike B.1.1.7 And B.1.351 Variants: Mutation-Induced Allosteric Modulation Mechanism Of Functional Dynamics And Protein Stability, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

Structural and functional studies of the SARS-CoV-2 spike proteins have recently determined distinct functional states of the B.1.1.7 and B.1.351 spike variants, providing a molecular framework for understanding the mechanisms that link the effect of mutations with the enhanced virus infectivity and transmissibility. A detailed dynamic and energetic analysis of these variants was undertaken in the present work to quantify the effects of different mutations on functional conformational changes and stability of the SARS-CoV-2 spike protein. We employed the efficient and accurate coarse-grained (CG) simulations of multiple functional states of the D614G mutant, B.1.1.7 and B.1.351 spike variants to characterize …

Gay Group Fighting For Sogie: Policy Advocacy Of The Elimination Of Sexual Violence Bill By Gaya Nusantara Organization, Lutfia Nurul Hidayati, Fierda Nurany

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

The aim of the research was to discover the importance of the agenda of the gay group in fighting for SOGIE towards the bill draft on the Elimination of Sexual Violence (ESV) through policy advocacy. In Indonesia, LGBTIQ groups remain getting violence and discrimination based on SOGIE. The problem was regarded as fight of the actors in a policy framework from the integrated advocacy theory which said by Roem Topatimasang. Integrated policy advocacy provides an important device for practitioner to make a policy change that was helped by an interested group. This research used a qualitative research method with a …

Three Complete Mitochondrial Genomes Of Shortfin Mako Sharks, Isurus Oxyrinchus, From The Atlantic And Pacific Oceans, Marissa Mehlrose, Andrea Bernard, Kimberly A. Finnegan, Lauren E. Krausfeldt, Jose V. Lopez, Mahmood Shivji

Biology Faculty Articles

We present complete mitogenome sequences of three shortfin mako sharks (Isurus oxyrinchus) sampled from the western Pacific, and eastern and western Atlantic oceans. Mitogenome sequence lengths ranged between 16,699 bp and 16,702 bp, and all three mitogenomes contained one non-coding control region, two rRNA genes, 22 tRNA genes, and 13 protein-coding genes. Comparative assessment of five mitogenomes from globally distributed shortfin makos (the current three and two previously published mitogenomes) yielded 98.4% identity, with the protein-coding genes ATP8, ATP6, and ND5 as the most variable regions (sequence identities of 96.4%, 96.5%, and 97.6%, respectively). These mitogenome sequences contribute resources …

Identifying Available Resources And Agricultural Practices Useful In Soil Fertility Management To Support Orange-Fleshed Sweet Potato Cultivation On Smallholder Farms In Mozambique, Rafaela Feola Conz, Engil Isadora Pujol Pereira, Abdul Naico, Maria Isabel Andrade, Johan Six

School of Earth, Environmental, & Marine Sciences Faculty Publications

Orange-fleshed sweet potato is an important source of macro-and micronutrients for humans, particularly in resource-poor rural communities. However, sweet potato cultivation removes large amounts of nutrients from the soil. Hence, soil fertility replenishment is vital to secure long-term food production. The lack of access to fertilizers hinders the ability of farmers to supply and replenish soil nutrients, intensifying food insecurity. This study aimed at identifying locally available organic residues and agricultural practices with potential application in soil fertility management to prevent soil degradation in southern Mozambique. We conducted a survey to gather information on the farmers’ demographics and farming systems …

Repurposing Metformin And Antifolates For The Treatment Of Hepatocellular Carcinoma, Sherouk Mohamed Tawfik

Theses and Dissertations

Hepatocellular carcinoma (HCC), one of the most prevalent types of cancers worldwide, continues to maintain high levels of resistance to standard therapy. As clinical data revealed poor response rates, the need for developing new methods has increased to improve the overall wellbeing of patients with HCC. Due to its safety, wide availability and previously reported anti-cancer effects, metformin (MET) serves to be a possible therapeutic agent when combined with other well-known anti-cancer agents. The aim of this study was to investigate the potential anti-cancer effects of MET, an anti-diabetic agent, when combined with two antifolate drugs: trimethoprim (TMP) or methotrexate …

Design And Fabrication Of Nanostructured Electrodes For Complementary Electrochemical And Photoelectrochemical Water Splitting, Kholoud El Sayed Abousalem

Theses and Dissertations

Designing highly active, durable, and nonprecious electrodes for overall water splitting is of urgent scientific importance to realize sustainable hydrogen production. Accordingly, the need to search efficient energy production systems is of crucial necessity. In this thesis, two various systems for sustainable hydrogen production have been reported using electrochemical and photoelectrochemical pathways. In the first part of the thesis, electrochemical water splitting involving both hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) has been established. To this end, an innovative approach is demonstrated to synthesize flower-like 3D homogenous trimetallic Mn, Ni, Co phosphide catalysts directly on nickel foam via …

Knockdown Of Mdm2 In Hepg2 Cell Line: A Step Towards Understanding The Relation Between Mirna590-3p And Its Downstream Target Gene, Mdm2, In Hepatocellular Carcinoma, Jihad Mahmoud

Theses and Dissertations

Background: miRNA 590-3p is a small non-coding RNA that has previously been associated with the occurrence and progression of several cancer types. Its expression pattern and biological role in Hepatocellular carcinoma (HCC), however, remain controversial. Interestingly, a previous study in our lab revealed a tumor suppressing activity of miR-590-3p in HCC and identified the MDM2 gene as the miR-590-3p target gene.

Aim: The current study aimed to knock down the expression of MDM2 in HepG2 cells to understand how the inhibition of MDM2, as a validated downstream target of miR-590-3p, would affect different functional pathways in HCC. In …

Mathematical Modeling And Optimization Of Water Efficiency In Residential Buildings, Mahmoud Amin

Theses and Dissertations

Water scarcity is a global issue that is rapidly worsening. The domestic sector is one of the fastest-growing segments of world water usage. Many researchers have explored various approaches to promote sustainable uses of water, with Greywater (GW) recycling and utilization of innovative plumbing fixtures among the methods presented to reduce freshwater consumption for domestic usage. Nonetheless, previous studies have dealt with both means independently, with limited analysis of the integrated effect of utilizing GW recycling with innovative plumbing fixtures, both on quality of supplied water, as well as on cost of the integrated system. Accordingly, this research aims at …

Final Bid Price Estimation For Negotiated Contracts: Bargaining Game Theory Approach, Amr El Mahallaoui

Theses and Dissertations

The wide use of the low bid method by employers for awarding construction contracts has created an aggressively competitive environment among contractors in the construction industry. As a result, a contractor may resort to use a low mark-up percentage for his bid to increase his chances of winning, which may lead to losses and conflicts in case he is awarded the project. Additionally, a contractor who reaches the final negotiations stage for a certain project is faced by the dilemma of the minimum discount percentage he may need to offer to the employer that maximizes his chance to win the …

Ndls Communicator: Week Of 01.31.22, Notre Dame Law School

NDLS Communicator

The Latest News

• ND Law’s Program on Church, State & Society receives a transformational gift
• Randy Kozel publishes a new paper
• A.J. Bellia to present a paper at a conference at the University of San Diego
• Roger Alford mentioned in Committee on the Judiciary Hearings
• Emily Bremer publishes new paper
• Felicia Caponigri publishes article and co-edited Symposium in the International Journal of Constitutional Law
• Jimmy Gurulé writes op-ed for Indianapolis Star
• Mary Ellen O’Connell discusses Russia-Ukraine crisis
• Carter Snead speaks about his book on two podcasts
• Lloyd Mayer to present at ABA Midyear Tax Meeting
• Diane Desierto and Carter Snead …

A Predictive Model For Geographical Location Using Microbiome Composition And Covid-19 Based Analysis, Ahmed Adel Aboushanab

Theses and Dissertations

The human microbiome is a main contributor for the health and welfare of the human body. It is affected by many factors like diet and hygiene. These factors differ between different populations. Testing the population-microbiome differences using healthy samples from different countries is the first objective of this study. This data was then used in training and testing machine learning models (Random Forest and L2-logistic Regression Classifiers) for the prediction of the geographical location based on the microbiome data. Random Forest Classifier had the highest accuracy. Feature importance analysis showed that the data for Proteobacteria, Actinobacteria, and Bacteroidetes improved the …

Selective Gsk3Β Inhibition Mediates An Nrf2-Independent Anti-Inflammatory Microglial Response, Mohamed H. Yousef

Theses and Dissertations

Glycogen Synthase Kinase 3 (GSK3) is associated with the proinflammatory phenotype of microglia and has been shown to act in concert with Nuclear factor kappa B (NF-κB). . GSK3 is also a suppressor of Nuclear factor erythroid 2-related factor 2 (Nrf2), the principal regulator of redox homeostasis. Agreeing with the oxidative paradigm of aging, Nrf2 is often deregulated in parainflammatory and neurodegenerative diseases. In this study, we aimed to explore a multimodal disease-modifying utility of GSK3 inhibition, beyond neuronal proteopathologies, Furthermore, we aimed to underscore the difference in therapeutic value between the two GSK3 paralogs by isoform-selective chemical inhibition.

The …

Evaluation Of Hermetic Storage Bags For The Preservation Of Yellow Maize In Poultry Farms In Dormaa Ahenkro, Ghana, Bismark Opoku, Enoch Adjei Osekre, George Opit, Augustine Bosomtwe, Georgina Bingham

Department of Entomology: Faculty Publications

Using low-quality maize, resulting from insect pests and fungal attack, for formulating feed reduces chicken performance. This study evaluated the effectiveness of hermetic storage bags to keep insect pest and mycotoxin levels in check in yellow maize. The study was conducted in storehouses at three poultry farms in Dormaa Ahenkro, Bono Region, Ghana. The experiment was set up in a Randomized Complete Block Design with ZeroFly®Hermetic (ZFH), Purdue Improved Crop Storage (PICS), and Polypropylene (PP) bags as treatments. In each treatment, twelve 50 kg samples of untreated maize were each put in 100 kg capacity bags. Two bags in each …

Educational Policies Committee Agenda, February 3, 2022, Utah State University

Educational Policies Committee

• Approval of 2 December 2021 Minutes. Minutes approved as distributed.
• Subcommittee Reports
• a. Curriculum Subcommittee
• b. Academic Standards Subcommittee
• c. General Education Subcommittee
• Other Business (USHE)