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Articles 15091 - 15120 of 830599
Full-Text Articles in Entire DC Network
Unplanned Extubations In Pediatric Critical Care: A Case-Control Study, Krista Wollny, Cameron B. Williams, Raghad Al-Abdwani, Carol Cartelle, Jason Macartney, Helena Frndova, Norbert Chin, Christopher Parshuram
Unplanned Extubations In Pediatric Critical Care: A Case-Control Study, Krista Wollny, Cameron B. Williams, Raghad Al-Abdwani, Carol Cartelle, Jason Macartney, Helena Frndova, Norbert Chin, Christopher Parshuram
Journal of Pediatric Intensive Care
Objectives: To quantify associations between the risk of unplanned extubation and patient-, environment-, and care-related factors in pediatric critical care; and to compare outcomes between children who did and did not experience an unplanned extubation. Methods: Retrospective case-control analysis including patients <18 years who experienced an unplanned extubation during ICU admission (2004-2014). Cases were matched by age, duration of mechanical ventilation, and date to control-patients (4:1) who were intubated but did not experience an unplanned extubation. Conditional logistic regression was used to evaluate associations between unplanned extubations and the abstracted characteristics. Results: We identified 1601 eligible controls matched to 458 case-patients. When adjusted for confounders, eight variables were associated with unplanned extubation: three patient-related factors (previous ICU admission, previous intubation, and the volume of secretions); one environment-related factor (patient room set-up); and four care-related factors (intubation route, and the use of sedation, muscle relaxation and restraints). Patients who had an unplanned extubation had longer length of stay, but lower rate of mortality. Conclusions: This is the largest case-control study identifying variables associated with unplanned extubation in pediatric critical care. Several are potentially modifiable and may provide opportunities to improve quality of care in controlled ICU environments.
Outbound Investment Restrictions And International Law’S Challenge, Harlan Grant Cohen
Outbound Investment Restrictions And International Law’S Challenge, Harlan Grant Cohen
Seattle University Law Review
The Outbound Investment Rule, restricting U.S. investment in certain Chinese advanced technology sectors, has largely been portrayed as an incremental measure, a modest extension to fill loopholes in the existing investment screening regime. But while perhaps the logical next step in the securitization of the economy, the Outbound Investment Rule actually reflects a momentous shift in the relationship between governments and business, one playing out in the United States and around the world and worth attention. Unlike traditional investment screening, the Outbound Investment Rule operates like a sanctions regime, designed not to protect the U.S. economy, but to hamper the …
Orthognathic Surgery: Why Is It Done?, Mia Gou
Orthognathic Surgery: Why Is It Done?, Mia Gou
Mentorship Program 2025-2026
No abstract provided.
Campus Assembly Minutes 02/19/2025, Campus Assembly
Campus Assembly Minutes 02/19/2025, Campus Assembly
Campus Assembly
No abstract provided.
The Indiana Statesman, February 19, 2026, Indiana State University
The Indiana Statesman, February 19, 2026, Indiana State University
Student Newspaper
Alex Kor speaks to Honors College; A Tad of Grad: An exhibition of color and wonder
Partial Mitochondrial Genome Of The Enigmatic Bermuda Fireworm Odontosyllis Enopla Verrill, 1900 (Annelida, Syllidae, Eusyllinae) And Its Phylogenetic Implications, Lynette D. Wyant, Brendan A. Cruz, Aydanni D. Gonzalez, Joshua M. Kovalcik, Maria A. Carolus, Lauren C. Hutto, Hope Chutjian, Jude C. Roman, Anneau Cappelmann, John J. Ankney, Aidan Popp, James B. Wood, D. Tye Pettay, Mercer R. Brugler
Partial Mitochondrial Genome Of The Enigmatic Bermuda Fireworm Odontosyllis Enopla Verrill, 1900 (Annelida, Syllidae, Eusyllinae) And Its Phylogenetic Implications, Lynette D. Wyant, Brendan A. Cruz, Aydanni D. Gonzalez, Joshua M. Kovalcik, Maria A. Carolus, Lauren C. Hutto, Hope Chutjian, Jude C. Roman, Anneau Cappelmann, John J. Ankney, Aidan Popp, James B. Wood, D. Tye Pettay, Mercer R. Brugler
Natural Sciences Faculty Publications
The Bermuda fireworm, Odontosyllis enopla Verrill, 1900, is a marine polychaete that displays a unique bioluminescent mating ritual. Despite the first sighting of O. enopla more than 534 years ago, molecular data have been limited. Several syllid mitogenomes are currently available; however, there are only three published genes for O. enopla: two partial mitochondrial genes (16S [508 bp] and cox1 [653 bp]; 1,161 bp total) and one partial nuclear gene (18S [1,339 bp]). This study bioinformatically mined previously published transcriptomes of O. enopla for mitochondrial reads and subsequently assembled and annotated a partial mitochondrial genome (10,172 bp). The partial mitogenome …
Gc Minutes Feb 19, 2026, Graduate Council
Gc Minutes Feb 19, 2026, Graduate Council
Graduate Council Minutes
No abstract provided.
Ai-Guided Binding Mechanisms And Molecular Dynamics For Mers-Cov, Pradyumna Kumar, Lingtao Chen, Rachel Yuanbao Chen, Yin Chen, Seyedamin Pouriyeh, Progyateg Chakma, Abdur Rahman Mohd Abul Basher, Yixin Xie
Ai-Guided Binding Mechanisms And Molecular Dynamics For Mers-Cov, Pradyumna Kumar, Lingtao Chen, Rachel Yuanbao Chen, Yin Chen, Seyedamin Pouriyeh, Progyateg Chakma, Abdur Rahman Mohd Abul Basher, Yixin Xie
Faculty Articles
The MERS-CoV (Middle East respiratory syndrome coronavirus) is a zoonotic virus with a high mortality rate and a lack of antiviral drugs, underscoring the need for effective therapeutic methods. Viral entry depends on interactions between viral surface proteins and human receptors, with Dipeptidyl Peptidase-4 (DPP4), a transmembrane glycoprotein, acting as the receptor for MERS-CoV. We employed Molecular Dynamics (MD) Simulations to identify critical interface residues under a high-performance computing (HPC) workflow for accelerated results. Target residue pairs were identified through analysis of salt bridge and hydrogen bond occupancy. The stability of these residues was confirmed through three independent MD Simulations …
A Case Study Of Suspected Sheep Losses Due To Chokecherry Not Death Camas, Kevin D. Welch, Clint A. Stonecipher, Stephen T. Lee, Daniel Cook, Benedict T. Green
A Case Study Of Suspected Sheep Losses Due To Chokecherry Not Death Camas, Kevin D. Welch, Clint A. Stonecipher, Stephen T. Lee, Daniel Cook, Benedict T. Green
Poisonous Plant Research (PPR)
Death camas (Zigadenus paniculatus) is a toxic plant often associated with poisoning cases in livestock, especially in sheep, in the spring on mountain foothills. Consequently, when sheep are found dead in mountain foothills, and death camas is present, it is often implicated as the potential cause of death. However, this may be over simplistic as there may be other plants that may also contribute to, or are the cause of, death in sheep. In this study, we present a case of approximately 200 sheep out of a band of 400 that died within 24 hours of beginning to …
Renin-Angiotensin-Aldosterone System In Preeclampsia: Pathophysiological Insights And Links To Vascular Dementia, Robin C. Finch, Jenny Lutshumba, Elizabeth Mirsky, Esther Ndashaala, Kelsey Bullens, Emma Smith
Renin-Angiotensin-Aldosterone System In Preeclampsia: Pathophysiological Insights And Links To Vascular Dementia, Robin C. Finch, Jenny Lutshumba, Elizabeth Mirsky, Esther Ndashaala, Kelsey Bullens, Emma Smith
Pediatrics Faculty Publications
Pre-eclampsia, a condition characterized by new-onset hypertension during pregnancy and one or more indices of organ damage, is a major driver of both short and long-term maternal health outcomes. Individuals with a history of pre-eclampsia are at increased risk for cardiovascular, renal, and other chronic diseases. Recent studies have linked pre-eclampsia history with increased risk of dementia later in life, underscoring the importance of new guidelines emphasizing blood pressure control to reduce the risk of cognitive decline. Unfortunately, neither mechanisms underlying causes of pre-eclampsia nor their links with cognitive function are well understood. Vascular contributions to cognitive impairment and dementia …
The Neuroprotective Effects Of Alpha-Tocopherol As An Anti-Inflammatory Agent: Mechanistic Insights And Therapeutic Challenges, Megumi H Seese, Yuanzhong Xu
The Neuroprotective Effects Of Alpha-Tocopherol As An Anti-Inflammatory Agent: Mechanistic Insights And Therapeutic Challenges, Megumi H Seese, Yuanzhong Xu
The Brown Foundation: Institute of Molecular Medicine
Vitamin E (alpha-tocopherol, αToc), an antioxidant fat-soluble vitamin that prevents lipid peroxidation and modulates pro-inflammatory cytokine production, is well-known to be critical for neuroprotection. However, the underlying mechanism remains poorly understood. Accumulating evidence demonstrates that αToc influences neuroinflammatory processes. Here, we review recent research progress on the effects of αToc on neuroinflammation. Preclinical studies included in this narrative review were identified through PubMed searches using the keywords "alpha-tocopherol AND neuroinflammation or alpha-tocopherol AND brain AND inflammation". While many studies support a neuroprotective role of αToc, the magnitude and direction of its effects vary substantially depending on dosage, route of administration, …
New Research Advances The Science Of Long-Term Organ Preservation, Beth Potier
New Research Advances The Science Of Long-Term Organ Preservation, Beth Potier
UNH Today Archive
No abstract provided.
Exploring Noise Induced Extreme Events In Neuronal Oscillators Networks And Machine Learning Forecasts, Hariharan S Mr
Exploring Noise Induced Extreme Events In Neuronal Oscillators Networks And Machine Learning Forecasts, Hariharan S Mr
Theses and Dissertations
This doctoral dissertation comprehensively investigates the underexplored phenomenon of noise-induced extreme events (EE). The word “extreme” is accompanied by an occurring “event” when the deviation is extreme or higher than that of regular occurrences. These extreme occurrences are rare, abrupt, sudden, and irregular, often causing a profound impact on the system and its surroundings. Tsunami, earthquakes, solar flares, and tornadoes are such events that do not occur often but still significantly cause damage to mankind. This thesis particularly focuses on EE in neuronal systems where sudden synchronization can trigger seizures, tremors, and strokes which serve as classic examples of such …
The Colby Echo (2026-02-19), Colby College
Spartan Daily, February 19, 2026, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily, February 19, 2026, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily, 2026
Volume 166, Issue 13
Nurse-Led Transformation: Evaluating The Impact Of A Professional Development Intervention On Interprofessional Collaboration, Amanda Kay Garey
Nurse-Led Transformation: Evaluating The Impact Of A Professional Development Intervention On Interprofessional Collaboration, Amanda Kay Garey
Creating Healthy Work Environments (CHWE)
Interprofessional collaboration (IPC) is critical in improving positive patient outcomes and achieving the quadruple aim of enhancing patient experience, improving population health, reducing costs, and improving the work-life balance of healthcare providers. Interprofessional collaboration (IPC) effectively enhances the patient experience and healthcare quality (McGuier et al., 2021). According to the Interprofessional Education Collaborative (IPEC), critical drivers for the ongoing growth of developing interprofessional collaborative practice include the need to empower the interprofessional (IPE) community with the best available evidence and research related to IPE and collaborative practice, conduct a continuous review of standard terms for competence, competency, and competency framework, …
Unbalanced Chromatin Binding Of Polycomb Complexes Drives Neurodevelopmental Disorders, Yingyu Huang, Lucas D Caeiro, Nikolai Fattakhov, Stefano Lepore, Liliana Garcia-Martinez, Matea Maurice, Pushti D Mehta, Emily J Park, Kailynn Macgillivray, Jevithen Nehru, Matthew Chau, Maria C Robayo, Clemer Abad, Alicia Bilbao-Martinez, Fabiola Monteiro, Xi Luo, Song Tan, Daniel Bilbao, Simone Sidoli, Bruno Di Stefano, Katherina Walz, Arneet L Saltzman, Ramiro E Verdun, Ramin Shiekhattar, Lluis Morey
Unbalanced Chromatin Binding Of Polycomb Complexes Drives Neurodevelopmental Disorders, Yingyu Huang, Lucas D Caeiro, Nikolai Fattakhov, Stefano Lepore, Liliana Garcia-Martinez, Matea Maurice, Pushti D Mehta, Emily J Park, Kailynn Macgillivray, Jevithen Nehru, Matthew Chau, Maria C Robayo, Clemer Abad, Alicia Bilbao-Martinez, Fabiola Monteiro, Xi Luo, Song Tan, Daniel Bilbao, Simone Sidoli, Bruno Di Stefano, Katherina Walz, Arneet L Saltzman, Ramiro E Verdun, Ramin Shiekhattar, Lluis Morey
Faculty, Staff and Students Publications
The prevalence of neurodevelopmental disorders (NDDs) in children is increasing, yet their underlying causes remain largely unknown. We identified heterozygous mutations in the Polycomb repressive complex 1 (PRC1) E3 ligases RING1 and RNF2 in individuals with NDDs and revealed distinct mechanisms by which they compromise PRC1 activity. We developed cellular and mouse models carrying the Ring1b
Cml-Like Biology Is A Unifying Feature Of Myeloid/Lymphoid Neoplasms With Tyrosine Kinase Fusions In Lymphoid Blast Phase Comment On: Multilineage Involvement In Abl-Class Fusion-Positive Pediatric B-Cell Acute Lymphoblastic Leukemia: Cml-Like Biology, Wei J Wang, Shimin Hu
Faculty, Staff and Student Publications
No abstract provided.
Temperature And Sex Ratios At Birth, Jasmin Abdel Ghany, Joshua Wilde, Anna Dimitrova, Ridhi Kashyap, Raya Muttarak
Temperature And Sex Ratios At Birth, Jasmin Abdel Ghany, Joshua Wilde, Anna Dimitrova, Ridhi Kashyap, Raya Muttarak
Publications, Reports and Presentations
Human sex ratios at birth (SRBs) shape population composition and are closely linked to maternal health and gender discrimination. In the context of environmental change, SRBs may theoretically be skewed by physiological or behavioral responses to exposure to extreme heat. However, evidence for this is limited. In this study, we estimate the effect of prenatal exposure to temperature on birth sex by linking survey data on 5 million live births in 33 sub-Saharan African countries and India with high-resolution temperature data. To distinguish between spontaneous and induced abortions, we exploit sociodemographic differentials, exposure timing, and regional differences in son preference. …
Montana Kaimin, February 19, 2026, Students Of The University Of Montana, Missoula
Montana Kaimin, February 19, 2026, Students Of The University Of Montana, Missoula
Montana Kaimin, 1898-present
Student newspaper of the University of Montana, Missoula.
Spectator 2026-02-19, Editors Of The Spectator
Adipocyte-Specific Deletion Of Sine Oculis Homeobox Homolog 1 Inhibits Lipolysis And Reduces Skin Fibrosis, Nancy Wareing, Tingting W Mills, Scott Collum, Minghua Wu, Lucy Revercomb, Hui Liu, Mikhail Kolonin, Marka Lyons, Brian Skaug, Weizhen Bi, Meer A Ali, Haniyeh Koochak, Anthony R Flores, Yuntao Yang, W Jim Zheng, William R Swindell, Shervin Assassi, Harry Karmouty-Quintana
Adipocyte-Specific Deletion Of Sine Oculis Homeobox Homolog 1 Inhibits Lipolysis And Reduces Skin Fibrosis, Nancy Wareing, Tingting W Mills, Scott Collum, Minghua Wu, Lucy Revercomb, Hui Liu, Mikhail Kolonin, Marka Lyons, Brian Skaug, Weizhen Bi, Meer A Ali, Haniyeh Koochak, Anthony R Flores, Yuntao Yang, W Jim Zheng, William R Swindell, Shervin Assassi, Harry Karmouty-Quintana
Faculty, Staff and Student Publications
Dermal fibrosis is a cardinal feature of systemic sclerosis (SSc) for which there are limited Systemic sclerosis (SSc) is characterized by dermal fibrosis accompanied by loss of dermal white adipose tissue (DWAT), yet the mechanisms linking adipocyte depletion to fibroblast activation remain unclear. Here we identify the transcription factor SIX1 as a central regulator coupling adipogenic repression with profibrotic signaling. SIX1 expression was increased in skin biopsies from two independent SSc cohorts and localized to fibroblast and perivascular stromal cells. In mice, ubiquitous or adipocyte-specific deletion of Six1 preserved DWAT, reduced collagen accumulation, and selectively decreased pro-fibrotic mediators. In cultured …
Crispr Spacers Reveal Diverse And Abundant Thermococcales Viruses In Hydrothermal Vents, Ryan Catchpole, Justin Mclean, Emily St John, Anna-Louise Reysenbach, Mart Krupovic, Michael P. Terns
Crispr Spacers Reveal Diverse And Abundant Thermococcales Viruses In Hydrothermal Vents, Ryan Catchpole, Justin Mclean, Emily St John, Anna-Louise Reysenbach, Mart Krupovic, Michael P. Terns
Biology Faculty Publications and Presentations
Viruses are the most pervasive biological entities on Earth and they profoundly shape host ecology and evolution. However, for many microbial lineages, knowledge of their viromes remains limited, especially for those inhabiting remote environments, including deep-sea ecosystems. Here, we leverage one of the most extensively cultivated and genomically characterized archaeal lineages, the Thermococcales, to identify novel viral genomes. By utilizing CRISPR spacers from isolates and spacer arrays reconstructed from metagenomes, we mined mobile genetic elements (MGEs) in 1,172 publicly available and newly sequenced hydrothermal vent metagenomic datasets. Comparative genomics and identification of viral hallmark proteins revealed 620 viral genomes across …
Reconstruction In Philosophy Of Mathematics, Davide Rizza
Reconstruction In Philosophy Of Mathematics, Davide Rizza
Dewey Studies
No abstract provided.
Pragmatism In Transition, Michael G. Festl
Jessica Heybach Interviews Clara Fischer, Jessica Heybach, Clara Fischer
Jessica Heybach Interviews Clara Fischer, Jessica Heybach, Clara Fischer
Dewey Studies
No abstract provided.
Research Note: Lest We Forget: John Dewey And Remembrance Education, Shane J. Ralston
Research Note: Lest We Forget: John Dewey And Remembrance Education, Shane J. Ralston
Dewey Studies
No abstract provided.
John Dewey's Pragmatic Philosophy As A Critique Of Economic Discourse, Maciej Kassner
John Dewey's Pragmatic Philosophy As A Critique Of Economic Discourse, Maciej Kassner
Dewey Studies
No abstract provided.
Field Philosophy: Deweyan Inquiry On Climate Change Adaptation Perspectives, Anthony Voisard
Field Philosophy: Deweyan Inquiry On Climate Change Adaptation Perspectives, Anthony Voisard
Dewey Studies
No abstract provided.
Editor's Intoduction, Leonard J. Waks