Digital Commons Network^™

Accountability As A Key Virtue In Mental Health And Human Flourishing, John R. Peteet, Charlotte Vanoyen-Witvliet, C. Stephen Evans

Faculty Publications

We propose that accountability plays an implicit, important, and relatively unexamined role in psychiatry. People generally think of accountability as a relation in which one party is held accountable by another. In this paper, we examine accountability as a virtue, drawing on philosophy, psychiatry, and psychology to examine what it means to welcome being accountable in an excellent way that promotes flourishing. When people manifest accountability as a virtue, they are both responsive to others they owe a response, and they are responsible for their attitudes and actions in light of these relationships. Psychiatric treatment often aims to correct disordered …

Accountability And Autonomy, Motivation, And Psychiatric Treatment, John R. Peteet, Charlotte Vanoyen-Witvliet, C. Stephen Evans

Faculty Publications

No abstract provided.

The Parthenon, March 23, 2022, Tyler Spence, Connor Woodruff, Tyler Kennett, Evan Green, Shauntelle Thompson, Rafael Alfonso, Abby Hanlon, Abby Ayes, Alaina Laster, Isabella Robinson

The Parthenon

No abstract provided.

Seasonal And Interannual Variation In High‑Latitude Estuarine Fsh Community Structure Along A Glacial To Non‑Glacial Watershed Gradient In Southeast Alaska, Anne H. Beaudreau, Carolyn A. Bergstrom, Emily Jean Whitney, Douglas H. Duncan, Nina Lundstrom

Faculty, Staff, and Students

Along the Gulf of Alaska, rapid glacier retreat has driven changes in transport of freshwater, sediments, and nutrients to estuary habitats. Over the coming decades, deglaciation will lead to a temporary increase, followed by a long-term decline of glacial influence on estuaries. Therefore, quantifying the current variability in estuarine fish community structure in regions predicted to be most affected by glacier loss is necessary to anticipate future impacts. We analyzed fish community data collected monthly (April through September) over 7 years (2013–2019) from glacially influenced estuaries along the southeastern Gulf of Alaska. River delta sites within estuaries were sampled along …

Seasonal And Interannual Variation In High‑Latitude Estuarine Fsh Community Structure Along A Glacial To Non‑Glacial Watershed Gradient In Southeast Alaska, Anne H. Beaudreau, Carolyn A. Bergstrom, Emily Jean Whitney, Douglas H. Duncan, Nina Lundstrom

Faculty, Staff, and Students

Along the Gulf of Alaska, rapid glacier retreat has driven changes in transport of freshwater, sediments, and nutrients to estuary habitats. Over the coming decades, deglaciation will lead to a temporary increase, followed by a long-term decline of glacial influence on estuaries. Therefore, quantifying the current variability in estuarine fish community structure in regions predicted to be most affected by glacier loss is necessary to anticipate future impacts. We analyzed fish community data collected monthly (April through September) over 7 years (2013–2019) from glacially influenced estuaries along the southeastern Gulf of Alaska. River delta sites within estuaries were sampled along …

From Distinct To Differential Conformational Dynamics To Map Allosteric Communication Pathways In Proteins, Xin-Qiu Joe Yao, Donald Hamelberg

Chemistry Faculty Publications

Initiation of biological processes involving protein–ligand binding, transient protein–protein interactions, or amino acid modifications alters the conformational dynamics of proteins. Accompanying these biological processes are ensuing coupled atomic level conformational changes within the proteins. These conformational changes collectively connect multiple amino acid residues at distal allosteric, binding, and/or active sites. Local changes due to, for example, binding of a regulatory ligand at an allosteric site initiate the allosteric regulation. The allosteric signal propagates throughout the protein structure, causing changes at distal sites, activating, deactivating, or modifying the function of the protein. Hence, dynamical responses within protein structures to stimuli contain …

Dissecting Mutational Allosteric Effects In Alkaline Phosphatases Associated With Different Hypophosphatasia Phenotypes: An Integrative Computational Investigation, Fei Xiao, Ziyun Zhou, Xingyu Song, Mi Gan, Jie Long, Gennady M. Verkhivker, Guang Hu

Mathematics, Physics, and Computer Science Faculty Articles and Research

Hypophosphatasia (HPP) is a rare inherited disorder characterized by defective bone mineralization and is highly variable in its clinical phenotype. The disease occurs due to various loss-of-function mutations in ALPL, the gene encoding tissue-nonspecific alkaline phosphatase (TNSALP). In this work, a data-driven and biophysics-based approach is proposed for the large-scale analysis of ALPL mutations-from nonpathogenic to severe HPPs. By using a pipeline of synergistic approaches including sequence-structure analysis, network modeling, elastic network models and atomistic simulations, we characterized allosteric signatures and effects of the ALPL mutations on protein dynamics and function. Statistical analysis of molecular features computed for the …

Developing A Community-Based Local Food System In Will County, Illinois: Insights From Stakeholders ’Viewpoints, Jerry H. Kavouras, Marie Asma Ben-Othmen

Biology Department Faculty Articles

The interest in and enthusiasm for shifting food systems to community-based and local trajectories have increased exponentially over the past decade. Part of the appeal of community-based, local food systems is their potential to secure access to heal­thy food for local communities, expand sustainable farming practices, promote local food economies, and advance environmental and food justice. Inter­actions and collaborations within the spectrum of the food system’s stakeholders—from farmers to local officials and organizations to local businesses and residents—are the cornerstone for effective food systems tailored to their community’s needs. An increasing number of food system studies have applied stakeholder assessment …

Qualitative Analysis Of Older Adults' Experiences With Sepsis, Rebecca D. Hancock

Dissertations

Atypical symptoms, multiple co-morbidities and a lack of public awareness make it difficult for older adults to know when to seek help for sepsis. Diagnosis delays contribute to older adults' higher sepsis mortality rates. This research describes patients' and caregivers' experiences with the symptom appraisal process, self-management strategies, provider-nurse-patient interactions, and barriers when seeking sepsis care.

Rapid Pivot Of Cure Wet Lab To Online With The Help Of Instructor Communities, Enid T. González-Orta, Deborah Tobiason, Brittany J. Gasper, Aarti Raja, Sarah Miller

Biology Faculty Articles

The pivot to remote and hybrid learning during the Covid-19 pandemic presented a challenge for many in academia. Most institutions were not prepared to support this rapid change, and instructors were left with the burden of converting a traditional face-to-face course into multiple modalities with very limited preparation time. When institutional support is lacking, we posit that instructor communities of practice can help provide the resources needed to meet the instructional demands. Tiny Earth, a course-based-undergraduate research experience (CURE) and international network of instructors and students, responded to the instructional challenges of the pandemic by leveraging its large community of …

The Gut Microbiome Of Exudivorous Marmosets In The Wild And Captivity, Joanna Malukiewicz, Reed Cartwright, Jorge A. Dergam, Claudia S. Igayara, Sharon E. Kessler, Silvia B. Moreira, Leanne T. Nash, Patricia A. Nicola, Luiz C. M. Pereira, Alcides Pissinatti, Carlos R. Ruiz-Miranda, Andrew T. Ozga, Adriana A. Quirino, Christian Roos, Daniel L. Silva, Anne C. Stone, Adriana D. Grativol

Biology Faculty Articles

Mammalian captive dietary specialists like folivores are prone to gastrointestinal distress and primate dietary specialists suffer the greatest gut microbiome diversity losses in captivity compared to the wild. Marmosets represent another group of dietary specialists, exudivores that eat plant exudates, but whose microbiome remains relatively less studied. The common occurrence of gastrointestinal distress in captive marmosets prompted us to study the Callithrix gut microbiome composition and predictive function through bacterial 16S ribosomal RNA V4 region sequencing. We sampled 59 wild and captive Callithrix across four species and their hybrids. Host environment had a stronger effect on the gut microbiome than …

From Here To Healthcare Career, Kassidy Taylor

UNH Today Archive

No abstract provided.

Spherical Nucleic Acids As Precision Therapeutics For The Treatment Of Cancer—From Bench To Bedside, Akanksha S Mahajan, Alexander H Stegh

Open Access Publications

Spherical Nucleic Acids (SNAs) emerged as a new class of nanotherapeutics consisting of a nanoparticle core densely functionalized with a shell of radially oriented synthetic oligonucleotides. The unique three-dimensional architecture of SNAs protects the oligonucleotides from nuclease-mediated degradation, increases oligonucleotide bioavailability, and in the absence of auxiliary transfection agents, enables robust uptake into tumor and immune cells through polyvalent association with cell surface pattern recognition receptors. When composed of gene-regulatory small interfering (si)RNA or immunostimulatory DNA or RNA oligonucleotides, SNAs silence gene expression and induce immune responses superior to those raised by the oligonucleotides in their "free" form. Early phase …

Accountability As A Key Virtue In Mental Health And Human Flourishing, John R. Peteet, Charlotte Witvliet, C. Stephen Evans

Faculty Scholarship

We propose that accountability plays an implicit, important, and relatively unexamined role in psychiatry. People generally think of accountability as a relation in which one party is held accountable by another. In this paper, we examine accountability as a virtue, drawing on philosophy, psychiatry, and psychology to examine what it means to welcome being accountable in an excellent way that promotes flourishing. When people manifest accountability as a virtue, they are both responsive to others they owe a response, and they are responsible for their attitudes and actions in light of these relationships. Psychiatric treatment often aims to correct disordered …

Office Of Research, Economic Engagement And Outreach Update, March 24, 2022, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Micrornas In Leukemias: A Clinically Annotated Compendium, Aleksander Turk, George A Calin, Tanja Kunej

Faculty, Staff and Student Publications

Leukemias are a group of malignancies of the blood and bone marrow. Multiple types of leukemia are known, however reliable treatments have not been developed for most leukemia types. Furthermore, even relatively reliable treatments can result in relapses. MicroRNAs (miRNAs) are a class of short, noncoding RNAs responsible for epigenetic regulation of gene expression and have been proposed as a source of potential novel therapeutic targets for leukemias. In order to identify central miRNAs for leukemia, we conducted data synthesis using two databases: miRTarBase and DISNOR. A total of 137 unique miRNAs associated with 16 types of leukemia were retrieved …

Targeted Dual-Modal Pet/Spect-Nir Imaging: From Building Blocks And Construction Strategies To Applications, Syed Muhammad Usama, Sierra C Marker, Servando Hernandez Vargas, Solmaz Aghaamiri, Sukhen C Ghosh, Naruhiko Ikoma, Hop S Tran Cao, Martin J Schnermann, Ali Azhdarinia

Faculty, Staff and Student Publications

Molecular imaging is an emerging non-invasive method to qualitatively and quantitively visualize and characterize biological processes. Among the imaging modalities, PET/SPECT and near-infrared (NIR) imaging provide synergistic properties that result in deep tissue penetration and up to cell-level resolution. Dual-modal PET/SPECT-NIR agents are commonly combined with a targeting ligand (e.g., antibody or small molecule) to engage biomolecules overexpressed in cancer, thereby enabling selective multimodal visualization of primary and metastatic tumors. The use of such agents for (i) preoperative patient selection and surgical planning and (ii) intraoperative FGS could improve surgical workflow and patient outcomes. However, the development of targeted dual-modal …

Spectrum, Volume 48, Issue 7, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: La Hispanidad Celebrates Social Justice Week -- Marching into Women's History Month -- One Year After... -- Native Ukrainian Speaks at SHU -- Is SHU's Campus Accessible to Everyone? -- SHU is "Stronger Together" -- Sacred Heart Professor Finalist for PR and Social Impact Award -- SHU Names New Interim Chief Diversity & Inclusion Officer -- Audrey's Corner: Poems for Social Justice -- TAP Presents "Sweat" -- Upcoming Multicultural Council Showcase -- The Every Heart is Sacred Initiative -- Ukraine Paralympic Team -- Jasmine Rogers: More than an Athlete

Midweek Memo, Georgia Southern University

Midweek Memo

• Applaud
• Remember
• Share
• Experience
• You May Have Heard

Faculty Senate Agenda

Faculty Senate Agendas

No abstract provided.

Endocrine-Disrupting Chemicals And Breast Cancer: Disparities In Exposure And Importance Of Research Inclusivity, Ashlie Santaliz Casiano, Annah Lee, Dede Teteh, Zeynep Madak Erdogan, Lindsey Trevino

Health Sciences and Kinesiology Faculty Articles

Endocrine-disrupting chemicals (EDCs) are known contributors to breast cancer development. EDC exposures commonly occur through food packaging, cookware, fabrics, and personal care products as well as through the environment. Increasing evidence highlights disparities in EDC exposure across racial/ethnic groups, yet breast cancer research continues to lack the inclusion necessary to positively impact treatment response and overall survival in these socially disadvantaged populations. Additionally, the inequity in environmental exposures has yet to be remedied. Exposure to EDCs due to structural racism poses an unequivocal risk to marginalized communities. In this review, we summarize recent epidemiological and molecular studies on two lesser-studied …

Exploring Magneto-Excitons In Bulk And Mono-Layer Semiconductors Using Non-Linear Spectroscopy Techniques, Varun Mapara

USF Tampa Graduate Theses and Dissertations

The research in two-dimensional (2D) materials has evolved from ``traditional" quantum wells based on group III-V and II-VI semiconductors to atomically thin sheets of van der Waals materials such as 2D semiconducting Transition Metal Dichalcogenides (TMDs). These 2D materials remain a stimulating field that continues to introduce new challenges. From both a fundamental physics and technological perspective, magneto-optical spectroscopy has been an essential tool in this research field. TMDs, for example, pose the challenge of characterizing their spin-valley-resolved physics and deriving implications in quantum computation and information research. With the discovery of valley Zeeman effects, the spin-valley physics of TMDs …

The Role Of Eicosanoid Metabolism In Mammalian Wound Healing And Inflammation, Kenneth D. Maus

USF Tampa Graduate Theses and Dissertations

Inflammatory wounds, both chronic and acute, lead to increased morbidity and mortality rates, especially in the elderly population. The annual healthcare cost for chronic wound care alone is over $39B in the US and the demographic of susceptible patients is steadily increasing due to an aging population and lifestyle-related diseases (e.g., hyperlipidemia, obesity, and type 2 diabetes). In fact, many chronic wounds currently have a worse 5-year outlook than certain types of cancers. This shows the need for expediting the wound healing process in such a way that compresses inflammatory signaling and encourages wound resolution without sacrificing pathogen removal and …

The Admission Conundrum: Working Closely With Admissions To Resolve Accounts Before Beginning School, Evelyn Nelson, Morgan O'Sullivan

Faculty and Staff Publications & Presentations

Through collaborating closely with the admissions office to develop a sound financial plan for incoming students, one institution’s student financial services office helped to recruit record numbers of students for the 2021–22 school year.

Through strategic communications and personalized service, accounts were resolved faster, aid was processed quicker, and the traditional stress and rush of fall orientation evaporated into just another workday. Discover how investing in time early in the process can bring about a transformation in fortunes.

Predictors Of Humoral Response To Sars-Cov-2 Mrna Vaccine Bnt162b2 In Patients Receiving Maintenance Dialysis, Li Tingting, Sumanth Gandra, Kimberly A. Reske, Margaret A. Olsen, Silvana Bommarito, Candace Miller, Karl G. Hock, Claire A. Ballman, Christina Su, Na Le Dang, Jennie H. Kwon, David K. Warren, Victoria J. Fraser, Christopher W. Farnsworth

Open Access Publications

No abstract provided.

Tusha Hiti: The Origin And Significance Of The Name, Deepak Shimkhada

Monsoon: South Asian Studies Association Journal

In this article, the author examines the royal bath called Tushā Hiti located in Sūndari Chowk (Beautiful Courtyard) of Pātan Durbar Square, using six different methods of investigation. The question: What is in a name? started the ball of investigation rolling and along the way were added more supporting blocks such as history, iconography, function and purpose, notion of purity and impurity, and finally the hiti in popular culture to get a complete picture of the subject in question.

Evaluation Of The Repeatability Of A Sports Technique Using Selected Kinematics Quantities Based On The Example Of Backhand Spring, Jaroslaw Omorczyk, Leszek Nosiadek, Ewa Puszczalowska-Lizis, Tadeusz Ambrozy, Dawid Mucha, Przemyslaw Bujas, Dariusz Mucha

Baltic Journal of Health and Physical Activity

Background: The aim of the study was to determine the changes that occur during a back handspring performed by artistic gymnastics competitors on the basis of selected biomechanical quantities. Material/Methods: The case study included five masterclass artistic gymnastics competitors. The activities were recorded at the frequency of 120 [Hz]. Using the SkillSpector computer software, selected biomechanical variables of the back handspring technique were analyzed. The coefficient of variation was used to evaluate the variability of movement, which, in turn, was used to describe the repeatability of the back handspring technique. Results: Kinematic analysis of the back handspring carried out with …

Iron Metabolism And Hepcidin Concentration In Teenagers Before And After Exercise In Relation To The Hfe Gene Status, Barbara Kaczorowska-Hac, Marcin Luszczyk, Jedrzej Antosiewicz, Jan Jacek Kaczor

Baltic Journal of Health and Physical Activity

Background: ‪The aim of the study was to compare the influence of exercise on iron metabolism and hepcidin concentration between carriers of His63Asp mutation (H63D polymorphism) and wild type HFE gene males. Iron is an essential micronutrient required for various biological processes. Systemic iron homeostasis is maintained in a hormone-like negative feedback mechanism by the 25-amino acid peptide hepcidin. Hepcidin controls duodenal iron absorption and iron recycling from senescent erythrocytes using tissue macrophages through the down-regulation of the sole known iron cell exporter, ferroportin-1. Exercise may induce an inflammatory response that leads to changes in iron metabolism. Material and methods: …

Fundamental Movement Skills And Weight Status In Children: A Systematic Review, Sari Slotte, Arja Sääkslahti, Katriina Kukkonen-Harjula, Pauli Rintala

Baltic Journal of Health and Physical Activity

Obesity has become a major health challenge in children. Fundamental movement skills(FMS) are suggested to have an important role for being physically active and decreasing the risk of obesity. This systematic review aimed to give an overview of studies providing evidence for a relationship between FMS and the weight status in children. A systematic search of five electronic databases (MEDLINE (PubMed), SportDiscus, ERIC, PsycInfo and SCOPUS) was conducted in January 2015. Studies examining associations between FMS and weight status in children aged 3–12 years were included. The final sample included 12 cross-sectional studies. Seven studies found statistically significant inverse association …

Obesity And Overweight Among Children And Adolescents In The Light Of Health Education Principles, Adam Wiek, Katarzyna Tkacz, Waclaw Mozolewski, Malgorzata E. Kusmierczyk, Sylwester Rybaczek

Baltic Journal of Health and Physical Activity

Pedagogical and educational institutions play an important role in health education. The proposed systemic principles should account for biological, environmental and cultural factors that determine the health of children and adolescents. Young people’s individual needs should constitute the framework of educational policy in the prevention of obesity and overweight. An analysis of health education practice in the Polish educational system indicates that the adopted measures, their practical applications and educational goals are adequate. Despite the above, the proposed systemic solutions are not always deployed or correctly implemented by the responsible institutions at various levels of local or social governance. The …