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How Early Education And Pet Therapy May Help Nurses With Compassion Fatigue, Katie E. Clark

Electronic Theses and Dissertations

Abstract

Although there is a great deal of research on the causes of compassion fatigue, there is little research on prevention techniques or ways to combat compassion fatigue. The purpose of this qualitative phenomenological study was to discover if nurses are prepared to cope with occupational stress and compassion fatigue. A secondary purpose was to examine the perceived benefit that pet therapy can have as a possible stress reduction technique to decrease the effects of compassion fatigue. This research was conducted by gathering data via semistructured interviews. The researcher interviewed nurses who were currently practicing patient care and scored as …

Exploring The Bedrock For Earth Jurisprudence, Maria Antonia Tigre

Sabin Center for Climate Change Law

This article calls for a reassessment of our core beliefs on how we relate to the environment through a deep dive into the philosophical foundations of environmental protection. With this purpose, it shows how Earth-centered discourses have existed in human societies and civilizations for millennia. Different religious and philosophical underpinnings all share a view of humanity as an integral part of an organic whole, revering all living things. While recent developments in jurisprudence may appear novel, they are somewhat latent and emergent. Theories of land ethics, rights of nature, Earth-centered environmental ethics, wild law, and Earth jurisprudence all build on …

Severe Asthma In Children: An Official Statement From Saudi Pediatric Pulmonology Association, Adel S. Alharbi, Abdullah A. Yousef, Saleh A. Alharbi, Talal M. Almaghamsi, Faisal M. Al-Somali, Turki S. Alahmadi, Sami A. Alhaider, Wadha H. Alotaibi, Mona A. Albalawi, Faisal N. Alotaibi, Ahmed S. Alenizi, Muslim M. Alsaadi, Yazan S. Said

Saudi Medical Journal

In Saudi Arabia, the prevalence of pediatric asthma ranges between 8% and 25%. However, there are no sufficient data regarding severe asthma in childhood in Saudi Arabia. Therefore, a task force has been formed by the Saudi Pediatric Pulmonology Association which is a subsidiary group of the Saudi Thoracic Society and consists of Saudi experts with well-respected academic and clinical backgrounds in the fields of pediatric asthma as well as other respiratory diseases to write a consensus on definitions, phenotypes, and pathophysiology, evaluation, and management. To achieve this, the subject was divided into various sections, each of which was assigned …

Evaluation Of The Effects Of Berberine In The Prevention Of Epidural Fibrosis In Rats: An Experimental Research, Emrah Keskin, Çağhan Tönge, Mustafa Kaya, Emre Işık

Saudi Medical Journal

Objectives: To evaluate the effect of berberine (BBR) in preventing the development of epidural fibrosis (EF) after lumbar surgery in rats. Methods: This experimental study was carried out at the animal laboratory of Zonguldak Bülent Ecevit University, Zonguldak, Trurkey, between April 2020 and June 2020. A total of 32 Wistar albino female rats underwent laminectomy and were divided into 4 equal groups. Group 1 did not receive any treatment (control group). In group 2, absorbable gelatin sponge was placed at the surgical site. Groups 3 was administered BBR 10 mg/kg and group 4 was administered BBR 60 mg/kg per oral …

The Effect Of Fetal Gender On The Biochemical Markers Of The First-Trimester Screening, Hakan Cokmez, Simge Tezel Yozgat

Saudi Medical Journal

Objectives: To determine the effects of fetal gender on the maternal levels of first-trimester screening biochemical markers, such pregnancy-related plasma protein A (PAPP-A) and beta-human chorionic gonadotropin (β-hCG). Methods: In this retrospective study, we assessed 267 cases of singleton pregnancies, who underwent first trimester screening tests and delivered between January 2016 and January 2019 at our hospital. Multiple of median (MoM) levels of PAPP-A and free β-hCG, and the neonatal genders according to the birth records were compared and analyzed. Additionally, patients with small for gestational age (SGA) newborns, preeclampsia, and placental ablation, called ischemic placental diseases, were classified into …

Environment-Driven Shifts In Inter-Individual Variation And Phenotypic Integration Within Subnetworks Of The Mussel Transcriptome And Proteome, Richelle L. Tanner, Lani U. Gleason, W. Wesley Dowd

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The environment can alter the magnitude of phenotypic variation among individuals, potentially influencing evolutionary trajectories. However, environmental influences on variation are complex and remain understudied. Populations in heterogeneous environments might exhibit more variation, the amount of variation could differ between benign and stressful conditions, and/or variation might manifest in different ways among stages of the gene-to-protein expression cascade or among physiological functions. Here, we explore these three issues by quantifying patterns of inter-individual variation in both transcript and protein expression levels among California mussels, Mytilus californianus Conrad. Mussels were exposed to five ecologically relevant treatments that varied in the mean …

Spatial Sequestration Of Misfolded Proteins In Neurodegenerative Diseases, Sarah Rolli, Emily M. Sontag

Biological Sciences Faculty Research and Publications

Properly folded, functional proteins are essential for cell health. Cells sustain protein homeostasis, or proteostasis, via protein quality control (PQC) mechanisms. It is currently hypothesized that a breakdown in proteostasis during ageing leads to the accumulation of protein aggregates in the cell and disease. Sequestration of misfolded proteins into PQC compartments represents one branch of the PQC network. In neurodegenerative diseases, certain proteins form abnormal protein deposits. Which PQC compartments house misfolded proteins associated with neurodegenerative diseases is still being investigated. It remains unclear if sequestration of these misfolded proteins is toxic or protective to the cell. Here, we review …

Leadership Influence: Adoption Professional, Birth Mother, And Adoptive Parents’ Knowledge Of Open Adoption, Vicki K. Colls

Doctoral Dissertations and Projects

Adoption needs a minimum of three sets of participants: the birth mother, the adoptive parents, and the adoptive professionals. Being the adoption expert, the adoption professional leads all parties through the process of adoption. However, as adoption research grows, it focuses on the adoptee, birth mother, and adoptive parents but rarely on the adoption professional. As the central figure in the adoption process, the assumption is the adoption professional would be the primary influencer affecting the culture of adoption practices. The purpose of this quantitative descriptive, correlational study was to evaluate if a relationship exists between the adoptive professional's leadership …

A Phenomenological Study Examining The Experiences Of Single Parents Who Are Rearing Elementary-Aged Children Enrolled In A Public School In A Rural Community, Jenine Lavonne Cotman

Doctoral Dissertations and Projects

Abstract The purpose of this qualitative transcendental phenomenological study was to examine the experiences of single parents who are rearing elementary-aged children enrolled in a public school in a rural community. Vygotsky’s sociocultural theory of cognitive development was used to guide this study. Vygotsky’s theory focuses on cognitive development being fundamentally framed by social interaction. Vygotsky also believed that cognitive development is strengthened when a child is encouraged to learn within their zone of proximal development, which refers to a person’s current cognitive space that can be further developed with social interaction and help from a teacher, peer, or parent. …

How Christian Teachers Perceive Their Engagement Facilitates Spiritual Formation Within At-Risk Male Students: A Case Study, Stephanie Eldridge

Doctoral Dissertations and Projects

The purpose of this qualitative intrinsic case study was to understand the experiences of teacher’s perception of their engagement to facilitate spiritual formation within at-risk students at Southeast Christian Alternative School (pseudonym). This participating school is recognized by the North Carolina Department of Administration as a non-public school. The program uses a Wilderness Therapeutic approach to learning. Four essential elements were explored. Teacher’s engagement concerning behavior management was assessed through processes that tactically managed disorderly conduct or acts of misbehavior. Implementation of any behavior plans or behavior models were applicable. Teacher’s engagement concerning spirituality was assessed through active practices of …

Differences Of Attitudes And Norms Toward Plagiarism Between First- And Continuing-Generation College Students, Michael Owen Harris

Doctoral Dissertations and Projects

This quantitative, causal-comparative study examines differences in attitudes and subjective norms between first- and continuing-generation college students toward plagiarism. Research studies have reported that up to 90% of college students admitted having committed plagiarism. Plagiarism harms the student who cheats, the reputation of the school, and all associated. First-generation college students experience greater challenges in their first years of college than their continuing-generation peers and may be more at risk for resorting to plagiarism. The researcher employed the Attitude Toward Plagiarism Questionnaire (Cronbach’s score of .79) to measure attitudes and norms toward plagiarism. The findings from the administration form the …

A Phenomenological Study Of The Student Engagement Experiences Of African Americans Formerly Attending Urban Public High Schools, Sohn A. Butts

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to interpret the student engagement experiences of African Americans formerly attending urban public high schools in a major city in the Mid-Atlantic region of the United States. Self-determination theory, established by Ryan and Deci (1985), is the theoretical framework for this study, and was used to understand motivation in terms of basic psychological needs satisfaction and fulfillment, and how those motivations influence human behavior. The central research question was: What were the student engagement experiences of African Americans formerly attending urban public high schools? The three research sub-questions were: (1) what instructional …

Evaluation Of The Effectiveness Of Non-Pharmacological Pain Interventions On Patient Reported Pain Scores And Opioid Use In Hospitalized Adult Patients, Tammy Jane Anderson

Doctoral Dissertations and Projects

The purpose of this integrative review is to research, critique, and synthesize current literature to ascertain the effectiveness of nonpharmacological pain management interventions on hospitalized patient reported pain scores and the use of opioids. Patients report pain while hospitalized for a variety of reasons. In order to become an active participant in their recovery, patients must have their pain adequately controlled. The use of opioids for main management may be required but alternatives exist. These alternatives do not have the same risk factors as opioid pain management. Nonpharmacological interventions included music, virtual reality, massage, guided imagery/hypnosis, and psychological interventions. All …

Prevalence And Correlates Of Food And Housing Insecurities At A Historically Black College, Melissa Massey Lockard

Doctoral Dissertations and Projects

The purpose of this quantitative, predictive correlational study was to determine the prevalence of food and housing insecurities at one historically Black college and explore whether these insecurities influence students’ academic performance or their mental health quality. The study also explored possible predictors of students at risk of experiencing these basic needs challenges. A convenience sample of 175 participant surveys was collected in the fall 2021 semester at the small, private, liberal arts college in urban South Carolina. The instruments used in the survey included the USDA’s 6-item Household Food Security Survey Module, the Housing Insecurity and Homelessness Module, the …

Lived Experiences Of Parents And Professionals With Technology And Emotional Dysregulation In Children, Ages 3-5-Years-Old: A Phenomenological Study, Angela P. Rathkamp

Doctoral Dissertations and Projects

Digital devices have become more extensively used and have created a dramatic shift in how children, adolescents, and families use this technology. Excessive screen time has been associated with increased behavioral health problems, sleep disturbances, anxiety, depression, and decreased family functioning. The relationship between problematic technology use and emotional dysregulation in young children is just emerging, therefore leaving a gap in research literature. The purpose of this study was to explore the lived experiences of parents and professionals with technology and emotional dysregulation in children ages 3-5-years-old and to identify emotional characteristics specific to technology and emotional dysregulation. It further …

An Investigation Of The Impacts Of Locus Of Control On Marital Satisfaction Among Wives Of Combat Veterans With Ptsd In The U.S., Rachel Sims

Doctoral Dissertations and Projects

Posttraumatic stress disorder (PTSD) is a significant cause of marital instability and divorce among PTSD veterans, which researchers have cited in the field of psychological disorders. The current study investigated the psychological structure of how marital satisfaction was related to the locus of control among wives of veterans with PTSD diagnosis. No prior studies have explored this relationship, as shown from an extensive search in current literature. The study compared the reported marital satisfaction of women with the locus of control to fill this gap. The family systems theory was applied to guide this research study. In addition, the study …

Examining The Correlation Between Childhood Trauma And Suicidal Ideation Among Air Force Airmen, Jennifer L. Thomas

Doctoral Dissertations and Projects

For decades, the United States military has been concerned about high suicide rates. Due to the increasing suicide rate within the armed forces, the need to better understand suicide-associated factors such as childhood trauma exposure is imperative. It is important to identify the research gaps that exist for promoting understanding of suicide and suicidal behavior and to enhance identification of those at risk for suicide. While there have been many published studies on the topic, conspicuously absent are studies that have included U.S. Air Force personnel. This research will examine the correlation between childhood trauma and suicidal ideation among Air …

The Significance Of Trauma In The Relationship Between Co-Occurring Disorders And Recidivism Among Participants Of A Community Mental Health's Jail Diversion Program, Emily A. Schott

Doctoral Dissertations and Projects

Abstract Individuals with a psychiatric diagnosis have higher levels of criminal justice involvement compared to the general population. Multiple programs have been developed through grant monies utilizing various models to allow these individuals to be linked to mental health services in the community for the treatment of symptoms which may contribute to recidivism. These programs are designed to provide an encounter with mental health professionals who collaborate with law enforcement and other agencies to intercept these individuals at various points of justice involvement and possibly prevent further entanglements with the legal system. This study explores how trauma may impact justice …

The Difference Between Grade 7 Female And Male Test Scores Based On One-To-One Technology Access: A Causal-Comparative Study, Windy Simonne Hammond

Doctoral Dissertations and Projects

This causal-comparative study sought to determine whether there was a relationship between the use of one-to-one technology and student achievement among female and male students in Grades 6 and 7 in public schools in South Carolina. This study adds to the body of literature that indicates academic gains occur from using one-to-one devices in classrooms and that these didactic technology tools are beneficial to all students. The current study analyzed the science and social studies achievement scores of 3,747 Grade 7 students, comparing females and males who had access to one-to-one technology to those who did not during the 2016–2017 …

Sabbath-Keeping And Mental Health: The Influence Of Weekly Sabbath-Keeping On Stress, Anxiety And Well-Being, Kathryn Mcnichol

Doctoral Dissertations and Projects

The purpose of the current study is to explore the effectiveness of a psychoeducational Sabbath intervention. Using a multiple baseline design, subsets of participants were assigned the psychoeducational intervention at varying times and completed a series of mental health questionnaires before, during, and after the intervention to assess its benefits. After receiving the psychoeducational intervention, participants began a weekly Sabbath-keeping practice. This study added to the limited existing literature on Sabbath-keeping and health, specifically mental health, by assessing the impact on anxiety, stress, and well-being. Results of this study indicated a potential connection between the practice of Sabbath-keeping and positive …

Understanding The Quality Of Life Of Parents Whose Young Adult Children Diagnosed With Asperger's Syndrome Live In A College Residential Setting: A Phenomenological Study, Faye Mcravion

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to understand, as a lived experience, the parents’ quality of life (QoL) with young adult children diagnosed with autism spectrum disorder (ASD) residing on a college campus. In addition, this study helped understand parent experiences related to factors about transition and their QoL. For parents of adult children with ASD in a college residency setting, many stressful and challenging times were attributed to their child living outside the home, which ultimately impacted parental stress and the parents’ QoL. The theory guiding this study is the Schlossberg Transition Theory (1981), and the 4 …

The Relationship Between Leader-Member Exchange And Citizen Willingness To Comply With Governmental Public Health Mandates Concerning Covid-19 In Dougherty County, Georgia: A Mixed Methods Analysis, Travis H. Goodson

Doctoral Dissertations and Projects

As of February 8, 2022, more than 394,381,395 individuals across the globe have contracted COVID-19; and from this number, reportedly more than 5,735,179 have died due to the virus (World Health Organization, 2022). Amid the COVID-19 pandemic, local, state, and federal governments have fielded a host of public health mandates in an attempt to curtail the spread of the virus; however, little is known about the efficacy of such mandates and how willing compliance is obtained through perceived high-quality leader-member exchanges. Compliance is best defined as willing conformity to official requirements; here, compliance is examined through the lens of relational …

Screening Commercial Entomopathogenic Fungi For The Management Of Diaphorina Citri Populations In The Lower Rio Grande Valley, Texas, Usa, Justin Wendel, Jonathan Cisneros, Stefan Jaronski, Christopher Vitek, Matthew Ciomperlik, Daniel Flores

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Ten strains of entomopathogenic ascomycete fungi, sourced from commercial formulations of blastopore or conidiospore formulations, were tested in 14 different formulations in a primary acquisition/direct spray bioassay against adult Asian citrus psyllid (Diaphorina citri Kuwayama (Hemiptera: Liviidae)). The Cordyceps (Isaria) javanica Apopka 97-C (conidia) strain was used as the standard. A statistical ranking system was established in which top performing pathogenic strains were selected for further screening and eventual field trials. Modified Potter-type spray towers were utilized to deliver a range of doses of viable spores to adult D. citri in an aqueous spray consistent with …

Cover Crops May Exacerbate Moisture Limitations On South Texas Dryland Farms, Stephanie Kasper, Faeqa Mohsin, Lindsey Richards, Alexis Racelis

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Cover crops are a sustainable management tool for mediating weed pressure, reducing soil erosion, and enhancing soil organic carbon (C) and nitrogen (N) levels. Yet, adoption rates across water-limited farms in Texas remain low, especially among producers without irrigation access, due to concerns that cover crop use of soil moisture will negatively impact subsequent cash crop yields. This three-year cover crop trial in a rain-fed sorghum (Sorghum bicolor L.) farm in Lyford, Texas, trialed different cover crop mixes and seeding rates and confirmed that cover cropping leads to significant soil moisture deficits and cash crop failure when rainfall is low …

Could Car-T Cell Therapy Be Promising Agent In Acute Lymphoblastic Leukemia?, Omar Khafagy, Shaimaa El-Ashwah, Ashraf Shoma

Mansoura Medical Journal

CAR T-cell therapy is a recent modality which uses the own T cells of the patient, CAR which represents the genetically engineered and modified fraction of the T cells, includes protein that permit T cells to attack the malignant cells. CAR T can provide long term control of the disease and potential protection against relapse. Chimeric antigen receptor (CAR) T-cell therapy is considered a novel powerful treatment for hematological malignancies. Toxicity still the most common challenge for CAR use. Most common toxicities are cytokine release syndrome and neurologic toxicity. Different factors may influence toxicities as disease burden, conditioning regimens, CAR …

Immunotherapy Forthyroid Eye Disesase, Aliaa Shohieb, Nashat Shawky, Ashraf Shoma

Mansoura Medical Journal

Thyroid eye disease (TED) is a complex autoimmune disorder that may lead to fundamental morbidity. TED presents with wide range of manifestations originating radically from orbital inflammation which leading to exophthalmos, vision impairment, double vision, severe eye dryness and in advance cases vision loss may occur. On top of that, it has also series of negative impacts on the patient quality of life, psychological and emotional well-being. The full clinical picture of thyroid eye disease (TED) can be explained by the enlargement of the orbit Corticosteroids are the gold stone of treatment in TED. However, in case of steroids withdrawal …

Tumor-Associated Macrophages In Multiple Myeloma: Advances In Biology And Therapy, Jennifer Sun, Chaelee Park, Nicole Guenthner, Shannon Gurley, Luna Zhang, Berit Lubben, Ola Adebayo, Hannah Bash, Yixuan Chen, Mina Maksimos, Barbara Muz, Abdel Kareem Azab

Open Access Publications

Multiple myeloma (MM) is a cancer of plasma cells in the bone marrow (BM) and represents the second most common hematological malignancy in the world. The MM tumor microenvironment (TME) within the BM niche consists of a wide range of elements which play important roles in supporting MM disease progression, survival, proliferation, angiogenesis, as well as drug resistance. Together, the TME fosters an immunosuppressive environment in which immune recognition and response are repressed. Macrophages are a central player in the immune system with diverse functions, and it has been long established that macrophages play a critical role in both inducing …

2022 Spring Vol. 39 No. 1, Alumni Affairs School Of Medicine

Medicinews

No abstract provided.

Luteolin Causes 5′Cpg Demethylation Of The Promoters Of Tsgs And Modulates The Aberrant Histone Modifications, Restoring The Expression Of Tsgs In Human Cancer Cells, Sreepoorna Pramodh, Ritu Raina, Arif Hussain, Sali Abubaker Bagabir, Shafiul Haque, Syed Tasleem Raza, Mohammad Rehan Ajamal, Shalini Behl, Deepika Bhagavatula

All Works

Cancer progression is linked to abnormal epigenetic alterations such as DNA methylation and histone modifications. Since epigenetic alterations, unlike genetic changes, are heritable and reversible, they have been considered as interesting targets for cancer prevention and therapy by dietary compounds such as luteolin. In this study, epigenetic modulatory behaviour of luteolin was analysed on HeLa cells. Various assays including colony forming and migration assays, followed by biochemical assays of epigenetic enzymes including DNA methyltransferase, histone methyl transferase, histone acetyl transferase, and histone deacetylases assays were performed. Furthermore, global DNA methylation and methylation‐specific PCR for examining the methylation status of CpG …

Carvacrol Alleviates Hyperuricemia-Induced Oxidative Stress And Inflammation By Modulating The Nlrp3/Nf-Κb Pathwayt, Muhammad Riaz, Lina Tariq Al Kury, Noreen Atzaz, Abdullah Alattar, Reem Alshaman, Fawad Ali Shah, Shupeng Li

All Works

Purpose: Gouty arthritis is generally induced by the accumulation of monosodium urate (MSU) crystals in the joints due to elevated serum uric acid levels, potentially leading to serious pathological disorders such as nephrolithiasis, renal failure, and acute gouty arthritis. In this study, we aimed to validate the anti-gout effects of carvacrol, a phenolic monoterpene. Materials and Methods: Male Sprague-Dawley rats were divided into normal saline, disease group by injecting potassium mono-oxonate (PO) at a dose of 250 mg/kg, and three treatment groups, either with carvacrol 20 mg/kg or 50 mg/kg and 10 mg/kg allopurinol. The blood and tissue samples were …