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Sleep Patterns & Sleep Problems Vary By Age In Children With Autism, Charles F Reynolds, Matthew Siegel, Briana Taylor Apr 2022

Sleep Patterns & Sleep Problems Vary By Age In Children With Autism, Charles F Reynolds, Matthew Siegel, Briana Taylor

Costas T. Lambrew Research Retreat 2022

Adolescence is a time of increased vulnerability for youth with autism spectrum disorder (ASD).1 • In non-ASD youth, sleep and circadian rhythms demonstrate marked changes during adolescence that delay the biological propensity for sleep.2 • In combination with early school start times, these agerelated changes in sleep and circadian rhythms result in insufficient sleep duration, circadian misalignment, daytime sleepiness, and numerous behavioral and psychiatric problems.3 • Age-related changes in sleep and circadian rhythms, and their relevance for behavioral and psychiatric health have not been examined in youth with ASD.


High Level Of Persister Frequency In Clinical Staphylococcal Isolates, Sarita Manandhar, Anjana Singh, Ajit Varma, Shanti Pandey, Neeraj Shrivastava Apr 2022

High Level Of Persister Frequency In Clinical Staphylococcal Isolates, Sarita Manandhar, Anjana Singh, Ajit Varma, Shanti Pandey, Neeraj Shrivastava

Faculty Publications

Staphylococcus aureus is a notorious human pathogen that causes often lethal systemic conditions that are mostly medical device associated biofilm infections. Similarly, coagulase negative staphylococci are emerging as leading pathogen for nosocomial infections owing to their ability to form biofilm on implanted medical equipment. Chronic in nature, these infections are difficult to treat. Such recalcitrance of these infections is caused mainly due to the presence of persister cells, which exhibit transient yet extreme tolerance to antibiotics. Despite tremendous clinical significance, there is lack of studies on persister cells formation among clinical bacterial isolates. Considering the importance of factors influencing persister …


Covid-19 Policies At Sports Venues: The Nfl Should Have Required Attendees To Be Vaccinated, David Caudill Apr 2022

Covid-19 Policies At Sports Venues: The Nfl Should Have Required Attendees To Be Vaccinated, David Caudill

Jeffrey S. Moorad Sports Law Journal (1994 - )

No abstract provided.


120 -- Schistosome Infections Affect On Hemoglobin In Ghana, David Marx, Wai Cheung Tung Apr 2022

120 -- Schistosome Infections Affect On Hemoglobin In Ghana, David Marx, Wai Cheung Tung

GREAT Day Posters

Schistosomiasis is a parasitic infection that affected nearly 237 million people worldwide in 2019, Africa, Asia, and South America are the most affected regions. Adult Schistosomes consume red blood cells in the human bodies, which may lead to anemia. Data were acquired from blood, stool, and urine samples of school children in the highly affected community of Tomefa in Accra, Ghana over the course of 6 years. Hemoglobin, eggs of Schistosoma mansoni and S. haemotobium were recorded. Anemic levels of hemoglobin were observed at high levels throughout the community regardless of infection status. Anemia is endemic within Ghana with around …


146 -- Testing The Integrity Of Calcium Phosphate Bioactive Cement Through Various Methods Of Drying, Jack Donaldson, Dean Ivanovski, Jack Donaldson, Matthew Chudy Apr 2022

146 -- Testing The Integrity Of Calcium Phosphate Bioactive Cement Through Various Methods Of Drying, Jack Donaldson, Dean Ivanovski, Jack Donaldson, Matthew Chudy

GREAT Day Posters

Autografting is the most effective method used for supplementing and replacing bone. Autografting is a risky procedure because of its invasive nature. When performing the procedure of autografting, one needs to remove small sections of bone to use as a stimulant at the fracture site. This study is made to design an alternative method to replace autografting. In our study, we used pig fibula as a model to compare the properties of our novel cement which is Calcium Phosphate based. Calcium Phosphate Cement (CPC) is ideal because it is a biocompatible bone substitute composed of Hydroxyapatite (HA), which constitutes a …


245 -- Bioethanol Production:Glucose Testing And Quantification Using Dns Analysis And Addition Analytical Methods, Dineen Vogler Apr 2022

245 -- Bioethanol Production:Glucose Testing And Quantification Using Dns Analysis And Addition Analytical Methods, Dineen Vogler

GREAT Day Posters

The search for alternative ways to create a more sustainable and environmentally friendly source of energy, other than fossil fuels, has been ongoing for many years. Particularly, the production of biofuels has become of interest. First generation biofuels were of interest as they curb greenhouse gas emissions, unlike fossil fuels. However, first generation biofuels lead to the increase in food prices as they utilize food sources toward biofuel production, which negatively impacts developing countries. To mitigate this issue, second generation biofuels are a more appealing alternative. Second generation biofuels aim to not affect the food supply, as they use non-human …


112 -- Purifying Total Rna To Explore The Role Of Pirnas In Zebrafish Stress Response, Alex Jakubiak, Lily Qian, William Chen Apr 2022

112 -- Purifying Total Rna To Explore The Role Of Pirnas In Zebrafish Stress Response, Alex Jakubiak, Lily Qian, William Chen

GREAT Day Posters

Tuna fish plays a significant economic and environmental role and contributes at least $40 billion annually to the global economy, but climate change has been rendering tuna populations particularly vulnerable to rising ocean temperatures and acidification. Recent studies have shown the emerging role of noncoding RNA (ncRNAs) such as piRNA in stress response and transgenerational inheritance. In order to assess the potential role of piRNA in tuna population’s response to climate stress, we use the zebrafish as a laboratory model to identify piRNAs whose steady-state levels change in response to conditions mimicking global climate change stress: elevated temperature, decreased pH …


Fast Photochemical Oxidation And Footprinting Of Proteins Via Trifluoromethyl Radical Chemistry, Elaine Morrow Apr 2022

Fast Photochemical Oxidation And Footprinting Of Proteins Via Trifluoromethyl Radical Chemistry, Elaine Morrow

Honors Theses

Fast photochemical oxidation of proteins (FPOP) is a useful tool in proteomics because of the ability for modifications to occur on the scale of microseconds which reduces the modifications to tertiary and quaternary structure allowing for more accurate labeling of the protein. Labels for FPOP are generated from various radicals in our experiments which include hydroxyl radicals and trifluoromethyl radicals. Hydroxyl radicals are easily generated by using an excimer laser (KrF laser, 248 nm) or a UV flash lamp (as a part of the Fox™ System) by the photolysis of hydrogen peroxide. Trifluoromethyl radicals, however, need hydroxyl radicals to be …


Racial Health And Productivity Inequalities In The United States, Elissia Vecere Apr 2022

Racial Health And Productivity Inequalities In The United States, Elissia Vecere

Honors Theses

Across America, it is frequently seen that there are may differences by race in economic and social outcomes. This variability can be seen in judicial, social, and economic systems. The breakdown of economic systems presenting racial variability can be displayed via workplace statistics. There is a general discrepancy between the workplace statistics represented with Black and White employees. These differences frequently are blamed on the productivity and background education supplied by the employee upon being hired. However, the levels of variation across these two races varies minutely in comparison to the differences in wages supplied. When all factors are kept …


The Cowl - V. 86 N. 18 - Apr 21, 2022 Apr 2022

The Cowl - V. 86 N. 18 - Apr 21, 2022

The Cowl

The Cowl - student newspaper of Providence College. Vol. 86 No. 18 - April 21, 2022. 24 pages.


Evaluating A Relationship Education Program With Incarcerated Adults, Terra L. Jackson, Francesca Adler-Baeder, Leah Burke, Silvia Vilches Apr 2022

Evaluating A Relationship Education Program With Incarcerated Adults, Terra L. Jackson, Francesca Adler-Baeder, Leah Burke, Silvia Vilches

Journal of Human Sciences and Extension

Research indicates healthy family relationships can reduce recidivism. More effort has been placed towards providing family life programming in prisons to promote healthy individual and relational functioning, yet only a handful of studies have evaluated and provided insight on relationship education (RE) for incarcerated adults. This study contributes to this emerging effort and examines changes following participation in a RE program, using a sample of 461 incarcerated men and women. Findings indicate significant improvements in anxiety and depressive symptoms and conflict resolution skills. Additional tests of moderation of change by gender, relationship status, and child age revealed a greater change …


150 -- Mapping The History Of Human Population And Development In Global Biodiversity Hotspots, 1000 To 2000 Ce, Emily Keenan Apr 2022

150 -- Mapping The History Of Human Population And Development In Global Biodiversity Hotspots, 1000 To 2000 Ce, Emily Keenan

GREAT Day Posters

Biodiversity (biological diversity) refers to the diversity of all life on Earth, including ecosystems and species. Currently, 36 areas globally are classified as biodiversity hotspots, defined as a region that contains high biodiversity levels that are also threatened by human population and development. The specific requirements for this classification follow two criteria: it hosts 1,500 endemic vascular plants, and at most 30% of its area is covered in original native vegetation present. This research maps the history of biodiversity hotspots with respect to changes in human population and land use from 1000 to 2000 CE. Results show that the biodiversity …


174 -- Does Male Display Behavior In An Ant-Mimicking Spider Depend On Context And Affect Female Response?, Julia Brzezicki, Marlena Ridley, Julia Cappiello Apr 2022

174 -- Does Male Display Behavior In An Ant-Mimicking Spider Depend On Context And Affect Female Response?, Julia Brzezicki, Marlena Ridley, Julia Cappiello

GREAT Day Posters

Myrmarachne formicaria is a species of ant-mimicking jumping spider native to Eurasia that was first noticed in the United States in 2001. These spiders get their name from their ant-like body forms and movement of their two forelegs to appear like antennae. They are also sexually dimorphic, with the males having enlarged chelicerae (jaws) that extend out from the front of their face. Males that encounter each other engage in displays that include faceoffs (facing one another and pacing back and forth), putting their abdomens to the side, opening their chelicerae, and even attacking/jabbing at one another. These male displays …


179 -- Analysis Of Kap Survey Data To Help Understand The Main Practices That Contribute To The Incidence Of Schistosomiasis Among School-Aged Children In Ghana, Grace Barnum, Queenie Adams Apr 2022

179 -- Analysis Of Kap Survey Data To Help Understand The Main Practices That Contribute To The Incidence Of Schistosomiasis Among School-Aged Children In Ghana, Grace Barnum, Queenie Adams

GREAT Day Posters

Schistosomiasis, also known as bilharzia, is a neglected tropical disease (NTD) that is more prevalent in tropical areas including Africa, South America, and the Caribbean. The WHO estimates that 90% of people who require treatment for schistosomiasis infections live in Africa. Our study focuses on data acquired from a small, marginalized community on the outskirts of the capital city of Accra in Ghana. Our sample includes individuals, both male and female, aged 8-26. The data was collected using KAP survey methods between 2016-2018. KAP surveys focus on analyzing knowledge, attitudes, and practices surrounding certain diseases. This method produces quantitative and …


196 -- Identifying Additional Dna And Rna Binding Domains Within The Reverse Transcriptase (Rt) Domain Of R2bm, Andrew Kareeparampil, Hima Chakka Apr 2022

196 -- Identifying Additional Dna And Rna Binding Domains Within The Reverse Transcriptase (Rt) Domain Of R2bm, Andrew Kareeparampil, Hima Chakka

GREAT Day Posters

Retrotransposable elements are selfish DNA elements that replicate within a host genome through an RNA intermediate. Long Interspersed Elements (LINEs), found in most eukaryotic genomes, are among the most abundant retrotransposable elements found in the human genome, accounting for over one-third of our DNA. Our study focuses on R2, a LINE element encoded from Bombyx mori (R2Bm) that specifically inserts into the 28S rRNA genes. The R2Bm has been exclusively used to study the biochemical steps by which R2 integrates into the host genome, known as target primed reverse transcription (TPRT). In TPRT, one subunit of the R2Bm, bound to …


198 -- The Impact Of Dna Methyltransferase On Bacterial Growth In E. Coli, Jessica Lopresti Apr 2022

198 -- The Impact Of Dna Methyltransferase On Bacterial Growth In E. Coli, Jessica Lopresti

GREAT Day Posters

The Dcm protein (DNA cytosine methyltransferase) catalyzes the process of DNA methylation, a process that has a large role in the regulation of gene expression in cells. The Dcm protein methylates at the second C at the 5’CCWGG3’ site. The specific consequences of this methylation are not known. We have been studying DNA methylation in E. coli by using two different measures of growth. The first experiment was a growth curve using absorption spectroscopy of wild-type E. coli and E. coli with a Dcm knockout gene at a temperature stressor of 42°C. We tracked the growth over eight hours, after …


192 -- Identification And Classification Of Changes In Protein Expression And Localization Associated With Epithelial To Mesenchymal Transitions In Human Vulvar Carcinomas After Exposure To The Glucocorticoid Analog, Clobetasol, Jennie Dworkin, Julia Malinchak, Kia Haering Apr 2022

192 -- Identification And Classification Of Changes In Protein Expression And Localization Associated With Epithelial To Mesenchymal Transitions In Human Vulvar Carcinomas After Exposure To The Glucocorticoid Analog, Clobetasol, Jennie Dworkin, Julia Malinchak, Kia Haering

GREAT Day Posters

It has been well established that decreases in cellular adhesions are associated with progression of squamous cell carcinomas to a malignant state. We have found that clobetasol treatment of A431 cells results in the initial loss of E-cadherin preceded by the gain of vimentin expression. Our system provides an inducible model to study this process. During clobetasol induced EMT in the A431 cells the expression of vimentin increases, but the cells do not lose expression of their cytokeratin molecules. Using Raman spectroscopy, we can identify key changes in metabolites associated with EMT between the A431 cells that respond to clobetasol …


199 -- Chaf1b Protein In Gef Mutant Zebrafish, Laura Ulrich, Brianna Donlon, Choeyang Choku, Jacqueline Maloney Apr 2022

199 -- Chaf1b Protein In Gef Mutant Zebrafish, Laura Ulrich, Brianna Donlon, Choeyang Choku, Jacqueline Maloney

GREAT Day Posters

Zebrafish embryos that are homozygous for gef mutant alleles experience a small-eye phenotype and are hypothesized to have decreased levels of the Chaf1b protein. This could be detected by anti-Chaf1b antibodies in a western blot. This western blot will be performed using Chaf1b morpholino 3 dpf embryos, wild type 3 dpf embryos, and gef mutant embryos 3 dpf. Embryos inoculated with Chaf1b morpholino serve as a negative control. This was then compared to the positive control of wild type zebrafish embryos, whose western blot was expected to have normal levels of Chaf1b. Proteins isolated from a gef mutant were then …


163 -- Timing Of Use Of Artificial Nests By Exotic Mason Bees, Stephen Hoare, Rachel Williams, Kaitlyn Latorre Apr 2022

163 -- Timing Of Use Of Artificial Nests By Exotic Mason Bees, Stephen Hoare, Rachel Williams, Kaitlyn Latorre

GREAT Day Posters

Solitary bees are a vital part of ecosystems due to their role in pollination of crops and native flowering plants. Some solitary bees, mason bees and leafcutter bees, use hollow cavities to rear their brood. Availability of above ground nesting sites is vital to their success. To promote these beneficial bees, people have set out artificial cavities for them to use. Unfortunately, exotic mason bees are outnumbering native mason bees in the eastern United States and may also benefit from these supplemental nest sites. In Spring 2020 boxes of hollow tubes for cavity-nesting bees were established at locations across SUNY …


202 -- The Effects Of Deforestation On Yellow Fever Virus Transmission, Meghan Sheridan Apr 2022

202 -- The Effects Of Deforestation On Yellow Fever Virus Transmission, Meghan Sheridan

GREAT Day Posters

Deforestation is increasingly associated with the transmission of zoonotic viruses, such as Malaria in South America and Ebola in Africa. Increasing rates of deforestation may cause viral transmission to accelerate. In this study, I asked how deforestation and other factors may interact to affect transmission of Yellow Fever virus. For example, deforestation in areas with higher precipitation may have different effects on animal hosts and mosquito vectors of the Yellow Fever virus compared to areas with lower precipitation. In addition, more densely-populated countries could have increased transmission compared to less densely-populated countries. Also, the ability to successfully treat viral transmission …


215 -- Determining The Function Of Mhc Class I In Xenopus Laevisusing Crispr/Cas9 Gene Editing, Sarah Eckl, Keely Glasheen Apr 2022

215 -- Determining The Function Of Mhc Class I In Xenopus Laevisusing Crispr/Cas9 Gene Editing, Sarah Eckl, Keely Glasheen

GREAT Day Posters

The MHC Class I protein plays a critical role in the immune system of Xenopus laevis. This protein functions in the determination between self and non-self. The MHC Class I protein is an important immune gatekeeper identifying foreign pathogens and ensuring that infected cells are killed by CD8 T cells. Also, it’s important to ensure that normal cells are not attacked by the immune system. In Xenopus laevis, it has been shown that MHC Class I molecules are found active in adult frogs, but have not been detected in tadpoles even though they are immunocompetent. We are interested to see …


216 -- Changing Perceptions Of Reproductive And Sexual Health: A Qualitative Content Analysis Of The New York Times (1960 Vs. 2020), Sara Rule Apr 2022

216 -- Changing Perceptions Of Reproductive And Sexual Health: A Qualitative Content Analysis Of The New York Times (1960 Vs. 2020), Sara Rule

GREAT Day Posters

Popular approaches to and understandings of reproductive and sexual health have changed greatly over the course of history. The changing quality of our collective perceptions of these topics is largely owed to the way in which news sources frame issues involving reproductive and sexual health. Comparing New York Times articles published in 1960 to those published in 2020, this research aims to analyze the role the media plays in framing certain practices involved in the maintenance of reproductive and sexual health and the claim of one’s bodily autonomy, as well as how this role has changed over time. Findings of …


235 -- Academic Experiences Of Suny Geneseo Students During The Covid-19 Pandemic, Miranda Fanara, George Konstantinou Apr 2022

235 -- Academic Experiences Of Suny Geneseo Students During The Covid-19 Pandemic, Miranda Fanara, George Konstantinou

GREAT Day Posters

The COVID-19 pandemic caused many colleges across the US to abruptly change their instructional modes from in-person learning to hybrid and online formats, and many students had difficulties with this transition. The extent of the disruptions to learning and transitioning back to in-person learning for SUNY Geneseo students is not fully known. Our research examines how students viewed their academic experiences during the pandemic semesters from Spring 2020 to Spring 2021, compared to Fall 2021. For these semesters, we created a voluntary and anonymous survey asking Biology majors and related minors to compare their perceptions of course difficulty, ways they …


237 -- Tetrahydrocannabinol Produces Locomotor Hyperactivity And Disrupts Circadian Rhythmicity In Pregnant Or Nursing Long-Evans Rats., Vincent Markowski, Joey Morgan, Anna Hendricks Apr 2022

237 -- Tetrahydrocannabinol Produces Locomotor Hyperactivity And Disrupts Circadian Rhythmicity In Pregnant Or Nursing Long-Evans Rats., Vincent Markowski, Joey Morgan, Anna Hendricks

GREAT Day Posters

Studies have demonstrated that exposure to cannabis during development impairs cognitive processes in humans, as well as locomotor activity and learning in animals. This extends to pregnant women and those caring for newborns. The legalization of marijuana can confer an underestimation of the effects of the more potent cannabinoids such as tetrahydrocannabinol (THC). This can lead to increased in utero exposure and postnatal exposure via breastfeeding. Newborns can also be affected if maternal care is compromised during an acute high. The current study used VitalView software and cage-top infrared activity monitors to quantify the effects of a range of THC …


238 -- Using Mathematical Modeling To Create A New Pyramidal Compost Bucket Design, Elizabeth Klosko Apr 2022

238 -- Using Mathematical Modeling To Create A New Pyramidal Compost Bucket Design, Elizabeth Klosko

GREAT Day Posters

SUNY Geneseo's campus has a compost collecting program where students, faculty, and staff can empty their compostable items into bins which are emptied weekly. However, the bins release a putrid scent when opened, deterring SUNY Geneseo community members from using them. A phenomena commonly known as Pyramid Power claims that the pyramid shape, when exactly scaled to the size of the Great Pyramid of Giza, has properties that, once compostable items are put under it, can limit the growth of microorganisms and therefore reduce the foul smell. Using a 3-D printing device, we will scale and print the pyramid to …


254 -- Fluorescent In-Situ Hybridization In Zebrafish With The Neurod4 Gene, Lin Kai Ye, Brynn Johnson Apr 2022

254 -- Fluorescent In-Situ Hybridization In Zebrafish With The Neurod4 Gene, Lin Kai Ye, Brynn Johnson

GREAT Day Posters

Zebrafish are used as a model organism within experimental retinal research due to the developmental process of their eyes being similar to that of humans. This developmental process consists of apoptosis triggering the muller glial cells within the retina causing proliferation of progenitor cells. Similarities between the retinal development of zebrafish and that of humans, has led to the further exploration of the transcription factor neurod4 which may be of importance throughout the process of neuronal development. Not much is known about neurod4 but it is hypothesized to have a correspondingly important impact on human neuronal development. Due to a …


055 -- Forelimb Morphology And Function Of Raptorex Kriegsteini (Dinosauria: Theropoda), Alexandria Scotti Apr 2022

055 -- Forelimb Morphology And Function Of Raptorex Kriegsteini (Dinosauria: Theropoda), Alexandria Scotti

GREAT Day Posters

Raptorex kriegsteini is a bipedal species of predatory dinosaur that belongs to the clade Tyrannosauridae. A Raptorex skeleton 3 meters in length was discovered in the northeast region of China, and it was estimated to be a 5 or 6 year old adult. One of the unique morphological features of this taxon is the forearm. Similar to Tyrannosaurus rex, the forelimbs of Raptorex are very small in proportion to the rest of their body in comparison to those of other nonavian theropods. In order to investigate the potential function of the limb of this taxon, an analysis of the forelimb …


066 -- Feeding Morphology Of Deep-Sea Demersal Fishes, Ryan Bohen, Chryssanthi Tzetzis Apr 2022

066 -- Feeding Morphology Of Deep-Sea Demersal Fishes, Ryan Bohen, Chryssanthi Tzetzis

GREAT Day Posters

Deep-sea inhabitants survive high pressure, limited food availability, lack of sunlight, and cold temperatures. These deep-sea conditions have spurred adaptations that allow organisms to fill an array of niches. For example, distinctive feeding modes and jaw morphologies enable organisms to utilize the food resources available in their environment. Here, we investigate feeding biomechanics in deep-sea fishes across three families of fishes, the rattails (Macrouridae), snailfishes (Liparidae), and cutthroat eels (Synaphobranchidae). Each of these families exist in abundance and occupy important ecological roles in their environment. We compare jaw morphologies and mechanics between families to gain insights into feeding mode, including …


077 -- Ironville Slag, Molly Smearing, Danielle Cox Apr 2022

077 -- Ironville Slag, Molly Smearing, Danielle Cox

GREAT Day Posters

Slag samples from Ironville, NY were analyzed to determine their mineral makeup. Slag is the byproduct that results from smelting, an industrial process used to separate a pure metal from an ore. A variety of samples were studied, and they range in their appearance from purple and blue glass, to gray and red vesicular material. All samples were crushed to a fine powder using a ball mill and then analyzed with the x-ray diffractometer (XRD). Glass was a main component of half of the samples we studied. The other half contained glass as well as crystalline materials. The crystals/minerals that …


085 -- Developing Resources For Assessing Genetic Diversity In A Non-Native Ant-Mimicking Spider, Cassidy Mills Apr 2022

085 -- Developing Resources For Assessing Genetic Diversity In A Non-Native Ant-Mimicking Spider, Cassidy Mills

GREAT Day Posters

The ant-mimicking spider Myrmarachne formicaria (Salticidae) is a species native to Eurasia and was first identified in North America in 2001. It has since been found in many locations in the Northeast including New York, Pennsylvania, Ohio, Ontario, and more recently as far as Chicago. Little is known about its introduction to North America and how it has dispersed since. By characterizing the mitochondrial and nuclear genetic diversity of this species, we can learn about its introduction history and dispersal patterns. Previous sequencing of two mitochondrial genes, CO1 and ND1, from 27 specimens collected from 14 localities in New York, …