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Cytokine Cxcl2 Concentration In The Cerebrospinal Fluid Of Patients With Aneurysmal Subarachnoid Hemorrhage Is Associated With Patient-Reported Headache Pain, Elizabeth Glisic, Joanne T. Dekay, Patricia Lerwick, David J. Gagnon, Richard Riker, Sergey Ryzhov

Costas T. Lambrew Research Retreat 2022

Subarachnoid hemorrhage (SAH) is a severe type of stroke categorized by a sharp, sudden, and persistent headache. The mechanism of headache after SAH is currently poorly understood but the neuro-inflammatory response has been identified as a target in understanding the causes of headache after SAH. A better understanding of this mechanism may lead to identification of molecular targets for therapeutic reduction of headache pain and improving outcomes after SAH. In this study, we collected cerebrospinal fluid (CSF) from patients hospitalized with SAH and conducted a cytokine array to screen for soluble factors involved in SAH-associated headache Introduction

Down The Drain: Stormwater Management Effects On The Quality Of The Westhampton Lake, Indya Woodfolk

Environmental Studies Senior Seminar Projects

This paper examines incidents of illicit discharges on the University of Richmond campus as outlined by the City of Richmond's MS4 permit. Illicit discharges contaminate the Westhampton Lake by flowing from our storm drains directly into the Westhampton Lake. I detected incidents of illicit discharges by performing visual inspections as guided by numerous scholarly articles. The visual inspections were done with a special consideration of land use on campus. Along with the visual inspections, I inspected the storm drains during a dry weather event to find whether there was any flow during this period. In this study, I found several …

Our Air: Determining Ideal Locations For Tree Planting In Richmond, Va In Order To Deter Inequalities In Temperature, Nina Vanatta

Environmental Studies Senior Seminar Projects

With the ever increasing effects of climate change, it is pertinent that an effective, efficient, and economic solution be reached in order to mitigate the extremity of urban heat islands. Since heat can contribute to a variety of health problems, it is very important that the unequal distribution of heat be minimized in order to promote the equal well-being within a city. One substantial and popular method of doing so is through the planting of trees, as there is research done to show that they reduce air pollution on top of reducing overall surface temperatures. This paper explores how and …

Red Wolf Reintroduction: Land Ownership And Protection Status Analysis, Anna Frisbie

Environmental Studies Senior Seminar Projects

Red wolves (Canis rufus) are critically endangered, and currently the only wild population exists in northeast NC (“Red Wolf,” FWS, n.d.). Here, I use geospatial analysis to investigate the potential for another wild population to establish in the Delmarva Peninsula. I consider land ownership and protection status because these factors influence local public support (Nie, 2001; Naughton-Treves et al., 2003; Berger-Tal et al., 2020), as well as reintroduction success (Carroll et al., 2003; Wolf & Ripple, 2018). I compare the ownership and protection status of land in the Delmarva Peninsula to that in the Albemarle Peninsula, where the red wolf …

Covid-19 Infection During Pregnancy Induces Differential Gene Expression In Human Cord Blood Cells From Term Neonates, Suhita Gayen Nee' Betal, Pedro Urday, Huda B. Al-Kouatly, Kolawole Solarin, Joanna Chan, Sankar Addya, Rupsa Boelig, Zubair H. Aghai

Department of Pediatrics Faculty Papers

Background: The COVID-19 pandemic continues worldwide with fluctuating case numbers in the United States. This pandemic has affected every segment of the population with more recent hospitalizations in the pediatric population. Vertical transmission of COVID-19 is uncommon, but reports show that there are thrombotic, vascular, and inflammatory changes in the placenta to which neonates are prenatally exposed. Individuals exposed in utero to influenza during the 1918 pandemic had increased risk for heart disease, kidney disease, diabetes, stomach disease and hypertension. Early exposure of COVID-19 during fetal life may lead to altered gene expression with potential long-term consequences.

Objective: To determine …

Covid-19 Impact On The Hospitalization Rates For Eating Disorders, Jennifer Ess

Honors Theses

The COVID-19 pandemic has had an impact in a variety of ways. With the quarantine restrictions placed during this time, many individuals had turned to social media as an outlet to cope with the loss of intimate time with friends and outside family. This increase in social media use, especially Tik Tok and Instagram, can negatively impact a person's outlook on certain situations. Throughout this pandemic, mental health issues, specifically eating disorders, have shown a rise in cases during this time. Current research shows that numbers have more than doubled during pandemic times, and also shows many different factors that …

Nr4a Family Genes: A Review Of Comprehensive Prognostic And Gene Expression Profile Analysis In Breast Cancer, Hassan Yousefi, Jordyn Fong, Suresh K. Alahari

School of Medicine Faculty Publications

This report analyzes nuclear receptor (NR) subfamily 4A’s potential role in treating those diagnosed with breast cancer. Here we reviewed the current literature on NR4 family members. We also examined the relative gene expression of the NR4A receptor subfamily in the basal, HER2 (human epidermal growth factor receptor 2) positive, luminal A, and luminal B subtypes using data from tumor samples in The Cancer Genome Atlas (TCGA) and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC). These data showed a positive link between NR4A1-NR4A3 expression and increased overall survival and relapse-free survival in breast cancer patients. In addition, we observed …

P-Flux: A Phosphorus Budget Dataset Spanning Diverse Agricultural Production Systems In The United States And Canada, M. R. Williams, P. Welikhe, J. Bos, K. King, M. Akland, D. J. Augustine, C. Baffaut, E. G. Beck, A. Bierer, D. D. Bosch, Elizabeth H. Boughton, C. B. Brandani, E. Brooks, Anthony R. Buda, M. Cavigelli, J. Faulkner, G. Feyereisen, A. Fortunato, B. Lee, Jason M. Unrine

Plant and Soil Sciences Faculty Publications

No abstract provided.

Rural Resiliency: The Cause And Effect Of Minnesota's Maternal Health Crisis, Annabel Traudie Gregg

Geography Honors Projects

The United States is experiencing a maternal health crisis that disproportionately affects those who give birth in rural communities. Rural birthing people have higher maternal mortality rates, increased risk of postpartum hemorrhage, non-indicated cesarean sections, and other adverse health outcomes. Despite the enhanced risks of rural birth, rural communities are losing access to hospital-based obstetric care at an unprecedented rate. Minnesota has vast rural territory, with one-fourth of its population living outside the urban sphere ­– making it a strategic area of study. As of July, 2021, 31% of Minnesota’s 91 rural hospitals were at risk of closing. The repercussions …

Intouch April 25, 2022, New York Medical College

InTouch

• D.P.T. Class of 2024 Marks the Transition to Clinical Education with White Coat Ceremony
• Sangmi Chung, Ph.D., Receives Bridge Funding Grant
• Erica Pratt, M.P.H. Class of 2022, Envisions Herself as a Public Health Leader
• The Office of Research Administration Supports NYMC’s Research Endeavors
• Kin Lazzaro Brings 15 Years of Fundraising Expertise to NYMC’s Office of Development and Alumni Relations

Spatial And Temporal Distribution And Habitat Selection Of Native Yellowstone Cutthroat Trout And Nonnative Utah Chub, Darcy K. Mccarrick, Jeffrey C. Dillon, Brett High, Michael C. Quist

United States Geological Survey: Staff Publications

Henrys Lake, Idaho, is a renowned trophy trout fishery that faces an uncertain future following the establishment of Utah Chub (UTC) Gila atraria. Utah Chub were first documented in the lake in 1993 and have become abundant over the past two decades. Little is known about the ecology of UTC, but they typically have negative effects on salmonids in systems where they have been introduced. We sought to fill knowledge gaps in UTC ecology and provide insight on potential interactions with Yellowstone Cutthroat Trout (YCT) Oncorhynchus clarkii bouvieri. Ninety-four YCT and 95 UTC were radio-tagged in spring 2019 …

Indispensable Role Of Immunophenotyping In Diagnosing Leukemic Phase Of Blastic Plasmacytoid Dendritic Cell Neoplasm Without Cutaneous Manifestation, Hareem Alam, Nabiha Saeed, Anila Rashid

Department of Pathology and Laboratory Medicine

Blastic plasmacytoid dendritic cell neoplasm usually presents as skin lesions. Diagnostic error occurs when it primarily presents in leukemic phase without skin involvement. Triad of CD4, CD56 and CD123 immunophenotype expression is essential to avoid misdiagnosis of this rare hematological malignancy. Here we describe a patient who presented in overt leukemic phase of BPDCN highlighting diagnostic challenges encountered that resulted in delayed diagnosis and poor outcome

Occupational Fine Particulate Matter Exposure And Its Associated Effects On The Cardiovascular System: A Systematic Review, Jordan Rickwa

Honors Theses

Fine particulate matter (PM2.5), the solid and liquid portion of air pollution under 2.5 microns in diameter, has been shown to cause numerous negative effects on the body. These inhalable particles are often researched for their effects on the respiratory system in outdoor settings, however systemic health impacts have been observed following inhalation of PM2.5 . Additionally, exposures to PM2.5 can occur in occupational settings but are less frequently studied compared to outdoors. This literature review seeks to identify studies that determined associations between inhaled PM2.5 and the resulting cardiovascular effects in occupational settings. We conducted a search of literature …

Targeting Platelets Using Ionic Liquid Coated Nanoparticles, Karen Mun Wong

Honors Theses

Platelets are key players in our body’s inflammatory processes upon activation, which can create physiological problems. Researchers are actively seeking solutions by targeting platelets with therapeutics. The objective of the research in this thesis was to investigate a new and potentially less invasive drug delivery platform using nanoparticles. The topic of the project was to explore the world of ionic liquids and their abilities, when coated on nanoparticles, to bind to platelets. A library of choline carboxylic acid-based ionic liquids (ILs) was first synthesized via salt metathesis while PLGA-based nanoparticles were simultaneously being synthesized via the nanoprecipitation method. The ionic …

The Free Press Vol. 53, April 04-25-2022, Cullen Mcintyre

Free Press, The

Masking required at first in=person commencement ceremony since beginning of pandemic--USM will hold the first in=person Students Leadership Awards Gala in several years--Spring Fling returns to USM following a break caused by the pandemic

Combination Olanzapine And Samidorphan For The Management Of Schizophrenia And Bipolar 1 Disorder In Adults: A Narrative Review, Hannah Haddad, Elena Boardman, Brooke Williams, Rama Mouhaffel, Adam M. Kaye, Alan D. Kaye

Student Publications

Schizophrenia is a debilitating psychotic disorder characterized by positive symptoms such as delusions, hallucinations, and disorganized thoughts, and negative symptoms like lack of effect or motivation. Bipolar 1 disorder (B1D) is a psychiatric illness characterized by recurrent manic episodes in alternation with depressive episodes and interspersed periods of euthymia, ultimately resulting in psychological distress and impairment of daily functioning. Effective treatments are needed for both schizophrenia and B1D to reach the treatment goals of reducing the debilitating symptomology, improving social functioning and quality of life, and increasing the chances of recovery and more favorable long-term outcomes. To date, olanzapine is …

Social Cognitive Theory Constructs That Predict Betel Nut Chewing Among Secondary Students In The Solomon Islands, Lepani Waqatakirewa, Manoj Sharma, Hadi Danawi, Ambrose Roots Gali

Journal of Sustainable Social Impact

Background: After alcohol, tobacco, and caffeine, areca or betel nut is the fourth most commonly abused substance in the world. The prevalence of betel nut use in the Solomon Islands is estimated at 68% in young people. Long-term use can result in detrimental health outcomes such as oral cancers and metabolic syndrome.

Methods: The purpose of this quantitative cross-sectional study was to determine whether the constructs of social cognitive theory (SCT) can predict betel nut use in Year 12 secondary students in the Solomon Islands. Five SCT constructs of expectations (outcome expectations and outcome expectancies), self-efficacy, self-efficacy to overcome barriers, …

A Multidisciplinary Mentoring Approach To Improve The Equity Of Nursing Education For The English Language Learner In An Undergraduate Nursing Program: A Mixed-Method Quality Improvement Project, Laurie Bisila

DNP and Student Works

This quality improvement (QI) project is a multidisciplinary approach to mentoring, matching a doctorate of nurse practice (DNP) student in their final year and a second-semester post-baccalaureate (PBN) nursing English language learner (ELL) student who is enrolled in an accelerated nursing program in a small Midwest private college. This QI project seeks to answer two questions. First, will a DNP mentor who is trained in the principles of cultural Competemility improve the sense of belongingness for the ELL undergraduate nursing student through six weekly mentoring sessions using the 12 domains in Purnell's model as a guideline? Secondly, does training on …

Feasibility Of Using Electronic Health Records For Cascade Monitoring And Cost Estimates In Implementation Science Studies In The Adolescent Trials Network For Hiv/Aids Interventions, Tyra Dark, Kit N. Simpson, Sitaji Gurung, Amy L. Pennar, Marshall Chew, Sylvie Naar

Publications and Research

Background:One of the most difficult areas in the fight against HIV/AIDS is reaching out to youth aged 13 to 24 years. The proportion of youth living with HIV/AIDS on antiretroviral therapy (ART) and who are virally undetectable is low, highlighting significant challenges for reaching the Joint United Nations Program on HIV targets.

Objective:This study aimed to assess the feasibility of obtaining key clinical indicators and monitoring treatment, viral suppression, and retention components of the youth HIV treatment cascade in Adolescent Trials Network for HIV/AIDS Interventions clinics using electronic health record (EHR) downloads and to provide baseline characteristics for the study …

22 Faculty Receive Grants To Fund Developmental Projects, Staff

Browse All News

No abstract provided.

Individual Trophic Niche Specialization In American Beaver (Castor Canadensis), Jimmy Taylor, Robert Francis, Scott Rush, Bronson Strickland, Guiming Wang

United States Department of Agriculture Wildlife Services: Staff Publications

The American beaver (Castor canadensis) has been described as a choosy generalist at the species/population scale, yet observational studies have shown little variation in diet among individuals. We compared isotopic values of δ¹³C or δ¹⁵N taken from hair of 32 beaver, representing seven colonies in northern Alabama, USA to determine 1) if colonies of beaver show overlap in isotopic niche width as a result of the similar use of food resources and 2) if individual trophic niche specialization occurs within colonies. Total Trophic Niche Width varied across the wetland with the widest being twice …

Effective Parameters Controlling Sterol Transfer: A Time‑Resolved Small‑Angle Neutron Scattering Study, Ursula Perez-Salas, Lionel Porcar, Sumit Garg, Manuela A.A. Ayee-Leong, Irena Levitan

Faculty Work Comprehensive List

Though cholesterol is the most prevalent and essential sterol in mammalian cellular membranes, its precursors, post-synthesis cholesterol products, as well as its oxidized derivatives play many other important physiological roles. Using a non-invasive in situ technique, time-resolved small angle neutron scattering, we report on the rate of membrane desorption and corresponding activation energy for this process for a series of sterol precursors and post-synthesis cholesterol products that vary from cholesterol by the number and position of double bonds in B ring of cholesterol’s steroid core. In addition, we report on sterols that have oxidation modifications in ring A and ring …

Identification Of Return-Oriented Programming Attacks Using Risc-V Instruction Trace Data, Daniel F. Koranek, Scott R. Graham, Brett J. Borghetti, Wayne C. Henry

Faculty Publications

An increasing number of embedded systems include dedicated neural hardware. To benefit from this specialized hardware, deep learning techniques to discover malware on embedded systems are needed. This effort evaluated candidate machine learning detection techniques for distinguishing exploited from non-exploited RISC-V program behavior using execution traces. We first developed a dataset of execution traces containing Return Oriented Programming (ROP) exploitation on the RISC-V Instruction Set Architecture (ISA) and then developed several deep learning bidirectional Long Short-Term Memory (LSTM) models capable of distinguishing exploited traces from non-exploited traces, each using subsets of features from the execution traces. An objective of this …

Surgical Management Of Vascular Tumors And Malformations Of The Head And Neck In Adults, Rachel A. Giese, Cristina Valero, Jatin P. Shah

School of Medicine Publications

Vascular tumors and malformations present a diagnostic and therapeutic challenge to many physicians. Because these lesions are rare, few surgeons have enough experience with them other than those practicing in tertiary vascular anomaly treatment centers. Some patients may have been misdiagnosed or mistreated during childhood and present in adult age with either recurrence or with an untreated lesion. Ideally, a multidisciplinary treatment team should be involved to discuss management with the patient including specialists in surgery, interventional radiology, pathology, hematology, genetics, and dermatology. As our understanding of the pathogenesis of these lesions grows, novel therapies are being employed which may …

Perceptions Of Expertise In Disability: Intersectional Considerations For Disclosure, Rachel Jocson

English: Student Scholarship & Creative Works

In this article, I will consider how perceptions of disabled tutees' expertise relate to disclosure through an intersectional lens. Specifically, drawing from reading writing center literature and my own experience to understand how the stigma around disability affects disclosure opportunities for tutees with marginalities considered atypical of disability.

Awareness Of Racial Disparities In Healthcare: An Analysis Of Undergraduate Science Students’ Perceptions, Liz Bleyer

Honors Scholars Collaborative Projects

General and systemic racial inequalities, including slavery, mass incarceration, and health disparities, have existed throughout the history of the United States. Recent public health issues, specifically the COVID-19 pandemic, have shed light on enduring health disparities, including the disproportionate impact on black communities and other racial minorities. A crucial first step towards a more equitable healthcare system is increasing general awareness of the presence and effects of racial disparities. Previous research has quantified and described the awareness of racial disparities in healthcare practitioners, including medical students and practicing physicians, but little research has been dedicated to understanding the perspectives of …

Development Of A Bio-Inspired Artificial Butterfly Vehicle, Thomas Payne Clark

Honors Capstone Projects and Theses

No abstract provided.

Tracking Academic Success And Its Relationship With Student Success Center Usage And Demographics, Samuel D. Johnson

Honors Capstone Projects and Theses

No abstract provided.

الآثار البيئية والاجتماعية والاقتصادية لظاهرة المد الأحمر على مجتمع الصيادين في ولاية السيب - سلطنة عمان, ثرياء بنت سعيد بن سالم العلوي, وعد بن عمر بن مرهون السيابي, أسمهان بنت خميس الجهوري, علي البلوشي

Journal of Arts and Social Sciences

شهدت العديد من سواحل العالم في العقود الأخيرة مجموعة من حوادث نفوق الأسماك والكائنات البحرية الأخرى بسبب ظاهرة المد الأحمر، الناتجة عن انتشار الطحالب الضارة. وتعد سواحل سلطنة عمان الممتدة على نحو 3165كم من السواحل التي تكررت عليها هذه الظاهرة.

Effects Of Seasonal Variation Of Abiotic Factors On Edna Detection Of Two Groundwater Crayfish Species, Jared Prine Higgs

Honors Capstone Projects and Theses

No abstract provided.