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Articles 13801 - 13830 of 817980

Full-Text Articles in Entire DC Network

Tead-Independent Mechanisms Of Yap Function In Cardiomyocyte Cell Cycle Reentry, Bing Xie, Jeffrey Steimle, Vaibhav Deshmukh, Lin Liu, Chang-Ru Tsai, Todd R Heallen, Wyatt Paltzer, Yuka Morikawa, Fansen Meng, Jun Wang, James F Martin Jan 2026

Tead-Independent Mechanisms Of Yap Function In Cardiomyocyte Cell Cycle Reentry, Bing Xie, Jeffrey Steimle, Vaibhav Deshmukh, Lin Liu, Chang-Ru Tsai, Todd R Heallen, Wyatt Paltzer, Yuka Morikawa, Fansen Meng, Jun Wang, James F Martin

Faculty, Staff and Students Publications

Adult mammalian hearts exhibit limited regenerative capacity because of the restricted renewal of cardiomyocytes. Recent studies reveal that mammalian hearts exhibit transient regenerative potential within a short time frame after birth, suggesting a regulatory mechanism that prevents adult hearts from initiating a regenerative response to cardiac injury. Here, we discovered that an active form of YAP, named YAP6SA, which is not inhibited by the Hippo signaling pathway and does not interact with TEADs, induces cardiomyocyte cell cycle reentry. In addition, YAP6SA interacts with scaffold protein MPDZ to regulate Rho GTPases and promote cell cycle progression in cardiomyocytes (CMs). Importantly, YAP6SA …

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Determination Of Residues Of 9 Herbicides Of International Concern In Dairy Products By High Performance Liquid Chromatography-Tandem Mass Spectrometry, Yan Wanying, He Minheng, Li Mingming, Huang Shiying, Chen Wenjing, Shen Yingtao, Huang Jiale Jan 2026

Determination Of Residues Of 9 Herbicides Of International Concern In Dairy Products By High Performance Liquid Chromatography-Tandem Mass Spectrometry, Yan Wanying, He Minheng, Li Mingming, Huang Shiying, Chen Wenjing, Shen Yingtao, Huang Jiale

Food and Machinery

[Objective] To establish a rapid and precise determination method for 9 herbicides (asulam, hexazinone, indaziflam, norflurazon, pyrasulfotole, pyroxasulfone, sulfosulfuron, tebuthiuron, and tepraloxydim) in dairy products that are of international concern but without established maximum residue limits (MRLs) in China. [Methods] The samples are ultrasonically extracted with acetonitrile-acetone mixed reagent (v∶v=8∶2), and the extract is purified by the dispersed solid-phase extraction adsorbents Florisil, N-propylethylenediamine (PSA), and anhydrous MgSO4. A high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method is established for determination. [Results] The nine herbicides are completely separated within 7 min. Their linear relationships are good within the range of 2.00~100 …

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Freshness Determination Of Winter Jujube Based On Improved Faster R-Cnn, Dai Haotian, Liu Wenlian, Zhu Meiyan, Zhang Ling, Zhu Liang Jan 2026

Freshness Determination Of Winter Jujube Based On Improved Faster R-Cnn, Dai Haotian, Liu Wenlian, Zhu Meiyan, Zhang Ling, Zhu Liang

Food and Machinery

[Objective] To propose a deep learning-based method for the freshness determination of winter jujube by dividing the fruit into five freshness stages, aiming to improve determination accuracy and reduce the influence of light reflection. [Methods] In this study, a freshness determination method is proposed for winter jujube by combining an efficient ResNet, an attention mechanism, and Faster R-CNN. First, ResNet is used for convolutional processing on the image to extract the global feature map. Next, key features are enhanced through a channel attention module, and multi-scale features are extracted using a feature pyramid network (FPN). Then, Faster R-CNN selects candidate …

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Effect Of Key Nrps Genes On Synthesis Of The Active Peptide Dlap In Ganoderma Sinense, Xiao Zhenyan, Wu Qiang, Wang Xiaoling, Huang Jia, Wang Haojin, Liu Gaoqiang Jan 2026

Effect Of Key Nrps Genes On Synthesis Of The Active Peptide Dlap In Ganoderma Sinense, Xiao Zhenyan, Wu Qiang, Wang Xiaoling, Huang Jia, Wang Haojin, Liu Gaoqiang

Food and Machinery

[Objective] To explore the key non-ribosomal peptide synthetase (NRPS) genes of the active peptide Asp-Leu-Ala-Pro (DLAP) with angiotensin-converting enzyme (ACE) inhibitory activity identified from the mycelia of Ganoderma sinense. [Methods] The effects of key NRPS genes on the synthesis of DLAP are analyzed by PEG-mediated genetic transformation experiment, real-time fluorescence quantitative PCR (qRT-PCR), and high performance liquid chromatography (HPLC). [Results] qRT-PCR results reveal that compared with the wild type, the silenced transformants of GSI_00900 have the reductions of 44.99%, 68.88%, and 66.17% in the expression level of this gene. The three silenced transformants of GSI_ 10299 show the reductions of …

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Optimization Of The Preparation Process And Antioxidant Activity Of Oligopeptides From Lueyang Black-Bone Chicken, Zhang Xinyue, Chen Rui, Chen Liwei, Li Haicheng Jan 2026

Optimization Of The Preparation Process And Antioxidant Activity Of Oligopeptides From Lueyang Black-Bone Chicken, Zhang Xinyue, Chen Rui, Chen Liwei, Li Haicheng

Food and Machinery

[Objective] To prepare oligopeptides from Lueyang black-bone chicken in order to increase its added value and to determine their antioxidant activity. [Methods] Lueyang black-bone chicken meat was used as the raw material. Two proteases were employed for compound enzymatic hydrolysis, and response surface methodology was applied to optimize the preparation process of Lueyang black-bone chicken oligopeptides and to evaluate their antioxidant activity. [Results] The optimal preparation process for compound hydrolysis of Lueyang black-bone chicken oligopeptides was as follows: neutral protease and acid protease in combination, substrate concentration 3 g/100 mL, enzymatic hydrolysis time 4 h, total enzyme addition 9 300 …

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Flavonoid Identification And Antioxidant Activity Of Ampelopsis Grossedentata Leaf Extract, Dai Haoxin, Yang Dawei Jan 2026

Flavonoid Identification And Antioxidant Activity Of Ampelopsis Grossedentata Leaf Extract, Dai Haoxin, Yang Dawei

Food and Machinery

[Objective] To investigate the composition and antioxidant properties of flavonoids from the Ampelopsis grossedentata leaf extract. [Methods] Qualitative identification and quantitative determination are conducted on flavonoids from the extract by high-performance liquid chromatography (HPLC). Then, with tea polyphenols and vitamin C as controls, the scavenging rates of the extract are determined against four free radicals, including OH-, DPPH, O-2, and ABTS+, and the antioxidant effect of the extract is studied during potato chip storage. [Results] The results show that the flavonoid and polyphenol content of the extract are 41.07% and 45.50%, respectively. There are five types of flavonoids in the …

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Effects Of Lactic Acid Bacteria Fermentation Modification On The Processing Properties Of Whole Grain Corn Flour, Liu Ji, Zhang Hongyan, Zhao Qiyuan, Ren Jian, Dong Qiang Jan 2026

Effects Of Lactic Acid Bacteria Fermentation Modification On The Processing Properties Of Whole Grain Corn Flour, Liu Ji, Zhang Hongyan, Zhao Qiyuan, Ren Jian, Dong Qiang

Food and Machinery

[Objective] This experiment aims to modify extruded whole corn flour through lactic acid bacteria fermentation to investigate its impact on the processing properties of dough. [Methods] Single-factor experiments are conducted using fermentation temperature, fermentation time, and inoculation amount of lactic acid bacteria as key variables. Response surface methodology is employed to optimize the fermentation conditions. After optimization, the modified extruded whole corn flour is blended with unmodified extruded whole corn flour in varying proportions, and its effects on the texture properties of the dough and cooking loss are investigated. [Results] Under the conditions of a lactic acid bacteria suspension concentration …

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Extraction And Purification Process Optimization Of Mango Kernel Polyphenols And Their Antioxidant Activity In Vitro, He Lingling, Hu Qinjiabao, Huang Bin, Luo Xu, Li Yunxin, Mai Xinyun Jan 2026

Extraction And Purification Process Optimization Of Mango Kernel Polyphenols And Their Antioxidant Activity In Vitro, He Lingling, Hu Qinjiabao, Huang Bin, Luo Xu, Li Yunxin, Mai Xinyun

Food and Machinery

[Objective] To explore the extraction and purification process and antioxidant activity of mango kernel polyphenols. [Methods] The extraction process of mango kernel crude polyphenols is optimized by the orthogonal experiment. Mango kernel polyphenol extract is further separated and purified by the macroporous adsorption resin. Meanwhile, the antioxidant activities of mango kernel polyphenols before and after purification are analyzed with Vc as the control. [Results] The optimal process extraction for mango kernel polyphenols is a solid-liquid ratio of 1∶40 (g/mL), 50% ethanol, an extraction temperature of 60 ℃, and an extraction time of 70 min. Under these conditions, the polyphenol yield …

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Optimization Of Tea-Flavored Rice Cake Preparation Process And Its Quality Analysis Based On Fuzzy Mathematics Comprehensive Evaluation Method, Chen Long, Xiang Chenxi, Yin Fangqi, Zheng Xueke, Li Jianfang Jan 2026

Optimization Of Tea-Flavored Rice Cake Preparation Process And Its Quality Analysis Based On Fuzzy Mathematics Comprehensive Evaluation Method, Chen Long, Xiang Chenxi, Yin Fangqi, Zheng Xueke, Li Jianfang

Food and Machinery

[Objective] To prepare tea-flavored rice cakes using a mixture of japonica rice flour and glutinous rice flour as the main raw material with the addition of tea dust by-products and analyze their quality. [Methods] Single-factor experiments were conducted to explore the effects of different tea dust addition amounts, white sugar addition amounts, and japonica-to-glutinous rice ratios on sensory evaluation and texture of tea-flavored rice cakes. Based on fuzzy mathematics sensory evaluation and comprehensive weighted scores of texture, orthogonal experiments were used to optimize the optimal preparation process for tea-flavored rice cakes and analyze their physicochemical and in vitro digestion characteristics. …

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Research Progress On The High-Value Processing And Utilization Of Processing By-Products Of Litopenaeus Vannamei, Wei Jie, Lin Haisheng, Huang He Jan 2026

Research Progress On The High-Value Processing And Utilization Of Processing By-Products Of Litopenaeus Vannamei, Wei Jie, Lin Haisheng, Huang He

Food and Machinery

Litopenaeus vannamei is one of the major cultivated species of shrimp products in China. With the rapid development of aquaculture technology, the production of L.vannamei has continued to rise in recent years, which has become an important economic pillar for export earnings and rural revitalization in coastal regions. The primary commercial processing products of L.vannamei include shrimp meat, shrimp surimi products, frozen whole shrimp, and preprocessed frozen shrimp. Substantial quantities of by-products (heads and shells) are generated during processing, yet current utilization strategies remain underdeveloped. As a result, issues such as resource waste, environmental pollution, and the reuse of by-products …

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Research Progress On Construction Strategies And Applications Of Protein-Based Composite Nanodelivery Systems, Xu Xiaojin, Xiong Xiangyuan, Gao Hongxia, Li Ziling Jan 2026

Research Progress On Construction Strategies And Applications Of Protein-Based Composite Nanodelivery Systems, Xu Xiaojin, Xiong Xiangyuan, Gao Hongxia, Li Ziling

Food and Machinery

In recent years, protein-based nanocarriers have attracted widespread attention for their excellent biocompatibility and superior delivery efficiency. However, single protein carriers suffer from some issues, such as high environmental sensitivity, insufficient targeting ability, and poor in vivo circulatory stability. The latest research progress of protein-based nanodelivery systems was analyzed, and common construction strategies were summarized and categorized, such as self-assembly technology, flash nanoprecipitation method, and pH-driven method;the advantages and limitations of different methods in particle size control and encapsulation efficiency were clarified. The coupling mechanisms, preparation methods, and application advantages of the composite systems composed of proteins and polysaccharides, inorganic …

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Research Advances In The Application Of Intelligent Responsive Hydrogels For Controlled Release And Quality Monitoring In Foods, Yin Hongli, Qu Yanfeng, Yang Jiaxing, Yao Jianuo, Li Weize, Liu Shiying Jan 2026

Research Advances In The Application Of Intelligent Responsive Hydrogels For Controlled Release And Quality Monitoring In Foods, Yin Hongli, Qu Yanfeng, Yang Jiaxing, Yao Jianuo, Li Weize, Liu Shiying

Food and Machinery

With the continuously increasing demand for intelligent and precise technologies in the food industry, intelligent responsive hydrogels, as an emerging class of functional materials, have demonstrated great application potential in controlled release and quality monitoring of food products. This article reviews recent research progress in intelligent responsive hydrogels in terms of base material selection and crosslinking methods, types of stimulus responsiveness, and underlying mechanisms. It elaborates on the design and application of intelligent hydrogels in controlled-release systems for food bioactive substances, covering antibacterial packaging, nutrient fortification, and flavor-controlled release. Additionally, the application of intelligent responsive hydrogels in food quality monitoring …

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Research Progress On Effects Of Processing Techniques On Mulberry Leaf Tea Quality, Liang Xiuhua, Ma Huanyan, Zhang Tanjie, Li Lamei, Lin Jie Jan 2026

Research Progress On Effects Of Processing Techniques On Mulberry Leaf Tea Quality, Liang Xiuhua, Ma Huanyan, Zhang Tanjie, Li Lamei, Lin Jie

Food and Machinery

Mulberry leaves serve as important raw materials with both medicinal and edible properties, rich in a variety of nutritional active ingredients. Processed mulberry leaf tea has antioxidant, hypoglycemic, hypolipidemic, anti-inflammatory, and other physiological functions, positioning it as a hot spot of research in the health food sector. Withering, fixation, fermentation, drying, stress treatment, and other processing techniques significantly affect the flavor quality, as well as the types and content of nutritional active ingredients of mulberry leaf tea, thereby affecting the nutritional quality and health benefits of the product. This study focuses on the effects of processing techniques such as withering, …

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Preparation And Characterization Of Nanocellulose-Based Edible Films And Their Fresh-Keeping Effects On Bananas, Tian Huan, Song Zhen, Li Zejun, Sun Yawen Jan 2026

Preparation And Characterization Of Nanocellulose-Based Edible Films And Their Fresh-Keeping Effects On Bananas, Tian Huan, Song Zhen, Li Zejun, Sun Yawen

Food and Machinery

[Objective] To prevent postharvest fruit decay and extend shelf life, a robust, water-resistant, and self-healing multifunctional edible fresh-keeping film was proposed. [Methods] The edible fresh-keeping film's microstructure, chemical structure, physicochemical properties, mechanical properties, and its effects on the shelf life of bananas were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray powder diffractometer (XRD), texture analyzer, and rheometer. [Results] The monomers within the edible film are cross-linked via hydrogen bonds, ester bonds, and electrostatic interactions, forming an irregular network structure on the surface. The film exhibits an elongation at break of 71.73% and a mechanical strength …

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Review Of Bootstrap Applications, Joshua Russell Jan 2026

Review Of Bootstrap Applications, Joshua Russell

Electronic Theses and Dissertations Archive

We investigate the bootstrap methodology and current applications. The bootstrap is a non-parametric resampling method that has universal applicability thanks to the statistical concepts of weak convergence, the law of large numbers, and the central limit theorem. Modern applications of bootstrap methodology have demonstrated time and time again that it is computationally efficient and robust. The earliest days of the bootstrap saw it validated by generating statistics, confidence intervals, and hypothesis tests. It is important to note the universal application and efficiency of the bootstrap, especially when researchers are tempted to utilize the more financially and computationally expensive techniques of …

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January 23, 2026 Ereporter, University Of Alabama At Birmingham Jan 2026

January 23, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

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Educating With Chronic Health Conditions During And After A Pandemic: A Narrative Study Of Experiences, Job-Related Stressors, Mental Health, Wellbeing And Coping Strategies Among Black Female Educators, Shawnee Stanfield Blake Jan 2026

Educating With Chronic Health Conditions During And After A Pandemic: A Narrative Study Of Experiences, Job-Related Stressors, Mental Health, Wellbeing And Coping Strategies Among Black Female Educators, Shawnee Stanfield Blake

Student Theses and Dissertations

This qualitative, narrative research study explored the experiences lived by black female educators with chronic health conditions during and after the Covid-19 pandemic in the Southeastern region of the United States. These educators provided continued instruction in a central Jackson, Mississippi school district and a Georgia school district in the central Atlanta metropolitan area. The investigation during this body of work focused on how black female educators with chronic health conditions were impacted both personally and professionally. The research also centered on how these educators employed coping strategies. Candidates endured fear, stress and continued impact on their health. To subject …

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Longfin Mako (Isurus Paucus) Jaw, Nicholas D. Burchett, David W. Kerstetter Jan 2026

Longfin Mako (Isurus Paucus) Jaw, Nicholas D. Burchett, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

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Male Great Hammerhead (Sphyrna Mokarran) Chondrocranium, Michelle W. Bassali, Nicholas D. Burchett, Samuel Escobar, Preston Rice, David W. Kerstetter Jan 2026

Male Great Hammerhead (Sphyrna Mokarran) Chondrocranium, Michelle W. Bassali, Nicholas D. Burchett, Samuel Escobar, Preston Rice, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Male ~10ft Great Hammerhead (Sphyrna mokarran) Chondrocranium

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Sustainability Implications Of Agricultural Practices In The Arkansas Delta: A Field To Market Approach, Melissa Adelle Palumbo Jan 2026

Sustainability Implications Of Agricultural Practices In The Arkansas Delta: A Field To Market Approach, Melissa Adelle Palumbo

Student Theses and Dissertations

The Field-to-Market Fieldprint Calculator is a software tool designed to estimate and compare relative sustainability of differing agricultural practices. This observational research compared conservation techniques to conventional practices in rice and cotton on three separate farms in Northeast Arkansas. Considering management and site conditions, the Fieldprint Calculator was used to compare sustainability metrics to standards at various spatial scales in a spidergraph report. Eight metrics were analyzed to produce reports, including greenhouse gas emissions, water quality and quantity, land and energy use, soil carbon and conservation, and biodiversity. Results showed no significant change in yield between the different production methods, …

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Cotton Production In The Arkansas Delta - A Focus On Water Quality Impacts, Trenton Alexander Barker Jan 2026

Cotton Production In The Arkansas Delta - A Focus On Water Quality Impacts, Trenton Alexander Barker

Student Theses and Dissertations

Farmers in Arkansas irrigate more farmland than 47 other states in the U.S. Agricultural production is a vital contributor to the economy of the state; however, it also contributes heavily to water quantity and quality issues within the Mississippi River Basin and the Gulf of Mexico. Row-crop producers have adopted soil and water conservation practices to mitigate these effects, yet many farmers remain hesitant to adopt conservation methods due to uncertainties about their effects on yield and profits. This thesis evaluates the water quality impacts of conventional and conservation cotton tillage systems under irrigated and rainfed conditions. Runoff, plant development, …

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Direct Solar-Energy Powered Hydrothermal Treatment To Promote Biomethane Production From Anaerobic Digestion Of Rice Processing Waste, Kainat Rahnuma Jan 2026

Direct Solar-Energy Powered Hydrothermal Treatment To Promote Biomethane Production From Anaerobic Digestion Of Rice Processing Waste, Kainat Rahnuma

Student Theses and Dissertations

Hydrolysis is a slow and energy-intensive process and a rate-limiting step in anaerobic digestion (AD). This research investigates performance strategies for integrating hydrothermal treatment (HT) with AD. HT-AD systems were less economically viable than AD-only options because of the high energy consumption of HT. Therefore, we used solar energy to conduct HT via either solar cookers or solar panels. The HT method significantly improved digestion performance, reducing the lag phase from 60 to 24 h, and increasing overall yield. Hydrothermally treated rice, rice bran, and rice hulls produced 22,932 mL, 13,136 mL, and 1283 mL, respectively. However, untreated rice, rice …

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Ai-Assisted Qualitative Analysis Of Formative Feedback To Support Student-Centered Learning In Physiology, Sulekha Anand, Ursula Holzmann, Alexander Y. Payumo Jan 2026

Ai-Assisted Qualitative Analysis Of Formative Feedback To Support Student-Centered Learning In Physiology, Sulekha Anand, Ursula Holzmann, Alexander Y. Payumo

Faculty Research, Scholarly, and Creative Activity

This study evaluates the effectiveness of large language models (LLMs), specifically Claude Sonnet 4.0 and ChatGPT 4.1, for analyzing formative feedback to support student-centered learning (SCL). In large courses, instructors often struggle to promptly review and synthesize student input. We used a low-stakes task: analyzing 63 anonymous student responses to a Muddiest Point prompt in a human physiology class after a lecture on respiratory physiology. Across 20 runs, both LLMs consistently identified "Ventilation and Lung Mechanics" as the most frequent area of confusion, aligning with human analysis. LLMs completed the task significantly faster than a human reviewer (average: 19.6 s/31.0 …

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Stories From Former Foster Youth College Graduates: The Positive Impact Of K-12 Schooling And Related Educational Policy, Amanda Moon, Kristen D. Seay Jan 2026

Stories From Former Foster Youth College Graduates: The Positive Impact Of K-12 Schooling And Related Educational Policy, Amanda Moon, Kristen D. Seay

Faculty and Staff Publications

Youth in foster care face disproportionate challenges when it comes to education and personal well-being. Many studies use a deficit lens when evaluating these challenges. In contrast, this study is asset-based, centering first-person accounts from five former foster youth college graduates. Using a counter-narrative framework, we conducted semi-structured interviews with participants to reveal key supports in K-12 schooling participants believed helped them achieve academic and life milestones. These were relationships with teachers and coaches, access to extracurricular activities, and literacy-rich environments. We also reviewed 11 relevant federal educational policies to identify provisions and implementation needs that aligned with participant experiences. …

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Scaling Pedestrian Crossing Analysis To 100 U.S. Cities Via Ai-Based Segmentation Of Satellite Imagery, Marcel E. Moran, Arunav Gupta, Jiali Qian, Debra Laefer Jan 2026

Scaling Pedestrian Crossing Analysis To 100 U.S. Cities Via Ai-Based Segmentation Of Satellite Imagery, Marcel E. Moran, Arunav Gupta, Jiali Qian, Debra Laefer

Faculty Research, Scholarly, and Creative Activity

Accurately measuring street dimensions is essential to evaluating how their design influences both travel behavior and safety. However, gathering street-level information at city-scale with precision is difficult given the quantity and complexity of urban intersections. To address this challenge in the context of pedestrian crossings — a crucial component of walkability — we introduce a scalable and accurate method for automatically measuring crossing distance at both marked and unmarked crosswalks, applied to America’s 100 largest cities. First, OpenStreetMap coordinates were used to retrieve satellite imagery of intersections throughout each city — totaling roughly three million images. Next, Meta’s Segment Anything …

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A Universal Of Human Social Cognition: Children From 17 Communities Process Gaze In Similar Ways, Manuel Bohn, Julia Christin Prein, Agnes Ayikoru, Florian M. Bednarski, Ardain Dzabatou, Michael C. Frank, Annette M.E. Henderson, Joan Isabella, Josefine Kalbitz, Patricia Kanngiesser, Dilara Keşşafoğlu, Bahar Köymen, Maira V. Manrique-Hernandez, Shirley Magazi, Lizbeth Mújica-Manrique, Julia Ohlendorf, Damilola Olaoba, Wesley R. Pieters, Sarah Pope-Caldwell, Katie Slocombe, Robert Z. Sparks, Jahnavi Sunderarajan, Wilson Vieira, Zhen Zhang, Yufei Zong, Roman Stengelin, Daniel B.M. Haun Jan 2026

A Universal Of Human Social Cognition: Children From 17 Communities Process Gaze In Similar Ways, Manuel Bohn, Julia Christin Prein, Agnes Ayikoru, Florian M. Bednarski, Ardain Dzabatou, Michael C. Frank, Annette M.E. Henderson, Joan Isabella, Josefine Kalbitz, Patricia Kanngiesser, Dilara Keşşafoğlu, Bahar Köymen, Maira V. Manrique-Hernandez, Shirley Magazi, Lizbeth Mújica-Manrique, Julia Ohlendorf, Damilola Olaoba, Wesley R. Pieters, Sarah Pope-Caldwell, Katie Slocombe, Robert Z. Sparks, Jahnavi Sunderarajan, Wilson Vieira, Zhen Zhang, Yufei Zong, Roman Stengelin, Daniel B.M. Haun

School of Psychology

Theoretical accounts typically assume that key features of human socio-cognitive development are universal. This paper reports a large-scale cross-cultural study (17 communities, diverse ethnicities, N = 1,377, 709 female, mean = 5.50 years, -collected March 2022 to January 2024) on gaze following in early childhood. To test for universality, cognitive processing signatures were derived from a computational model treating gaze following as social vector estimation. Results showed substantial variation between communities and individuals. Yet, the processing signature was found in all communities. Individual differences in performance were related to children's familiarity with the data-collection device but not opportunities for social …

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Communication Disorders Graduate Student: Perspective Of Voice, Maycie Brentney Terrell / Blankenship Jan 2026

Communication Disorders Graduate Student: Perspective Of Voice, Maycie Brentney Terrell / Blankenship

Student Theses and Dissertations

This study examined the influence of training in SPEAK OUT!® on the perceptual ratings of voice and speech made by communication disorders (CD) graduate students. The purpose of this study was to investigate the influence of SPEAK OUT!® training by comparing those who have undergone SPEAK OUT!® training with those who have not. To address this, 36 participants who attend communication disorders graduate programs within the United States were recruited. Data were collected through a Qualtrics survey distributed via email and analyzed using the Statistical Package for the Social Sciences (SPSS). The findings indicate that perceptual ratings across most voice …

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Investigating The Challenges That Black Female Superintendents Face While Navigating Local School Boards, Eric Dailey Jan 2026

Investigating The Challenges That Black Female Superintendents Face While Navigating Local School Boards, Eric Dailey

Student Theses and Dissertations

For the past twenty years, Black women have increasingly ascended to the role of school district superintendent. Black female superintendents navigate education systems that were not built with them in mind creating unique challenges. The purpose of this qualitative phenomenological study was to investigate the challenges that Black female superintendents face while navigating local school boards. This study was informed by glass ceiling theory, gendered organizations theory, and a black feminist framework establishing a research base for this study’s focus. Eight Black female superintendents were interviewed using an interview protocol. This study reveals that Black female superintendents experience similar challenges …

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High-Throughput Screens Identify Genotype-Specific Therapeutics For Channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, Björn C. Knollmann Jan 2026

High-Throughput Screens Identify Genotype-Specific Therapeutics For Channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, Björn C. Knollmann

Physiology Faculty Publications

Genetic diseases such as ion channelopathies substantially burden human health. Existing treatments are limited and not genotype specific. Here, we report a 2-step high-throughput approach to rapidly identify drug candidates for repurposing as genotype-specific therapy. We first screened 1,680 medicines using a thallium-flux trafficking assay against Kv11.1 gene variants causing long QT syndrome (LQTS), an ion channelopathy associated with fatal cardiac arrhythmia. We identified evacetrapib as a suitable drug candidate that improves membrane trafficking and activates channels. We then used deep mutational scanning to prospectively identify all Kv11.1 missense variants in an LQTS hotspot region responsive to treatment with evacetrapib. …

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Extraction Process Optimization Of Black Ginseng Polysaccharides By Compound Enzymes, Liu Xin, Xu Duoduo, Qiu Chaonan, Fan Bo, Hou Xiangzhu, Zhang Huijia, Gao Yang Jan 2026

Extraction Process Optimization Of Black Ginseng Polysaccharides By Compound Enzymes, Liu Xin, Xu Duoduo, Qiu Chaonan, Fan Bo, Hou Xiangzhu, Zhang Huijia, Gao Yang

Food and Machinery

[Objective] To optimize the extraction process of black ginseng polysaccharides (BGP) by an enzyme extraction method, and to investigate the antioxidant activity of BGP. [Methods] The optimal dosage of compound enzymes for BGP extraction is obtained using the orthogonal method, and the process conditions for BGP extraction by compound enzymes are optimized using the response surface method. The in vitro antioxidant activity of BGP is evaluated using the DPPH and the ABTS+ radical methods. [Results] The optimal enzyme ratio is 120 mg cellulase, 120 mg pectinase, and 80 mg papain. The optimal enzymatic hydrolysis process conditions are an enzymatic digestion …

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