Digital Commons Network^™

Anty 101h.80: Anthropology And The Human Experience - Honors, David Garrett Kerr

University of Montana Course Syllabi, 2026-2030

No abstract provided.

Anty 459.01: Archaeology Of The Arctic And Subarctic, Anna M. Prentiss

University of Montana Course Syllabi, 2026-2030

No abstract provided.

Anth 513.01: Seminar In Bioarchaeology & Skeletal Biology, Meradeth H. Snow

University of Montana Course Syllabi, 2026-2030

No abstract provided.

Bioh 291.01: Human Gross Anatomy – Cadaver Dissection, Lucas Whitcher

University of Montana Course Syllabi, 2026-2030

No abstract provided.

Biob 101n.51: Discover Biology - Online, Ashley L. Preston

University of Montana Course Syllabi, 2026-2030

No abstract provided.

Mapping Of Wetland And Riparian Habitat For The National Wetland Inventory: Wetland-21 Colorado, Ryhan T. Sempler, Melissa L. Moser, Emma R. Chantegros, Faith O. Hardin, Ella S. Hartshorn, Carver E. Butterfield, Kay L. Hajek

EMMA Publications

This report details the wetland and riparian mapping methodologies implemented for the Wetland-21 Colorado project. The project area consists of 106 1:24,000 US Geological Survey (USGS) quads across Western Colorado, with quads across Moffat, Rio Blanco, Garfield, Eagle, Mesa, Lake, Park, Delta, Gunnison, Chaffee, Fremont, Montrose, Ouray, Saguache, and Custer counties. There are also 3 quads partially located in Grand County, Utah.

Cc Magazine Winter 2026, Connecticut College

Alumni News/Connecticut College Magazine

No abstract provided.

The Role Of Spatial Abilities In Stem Learning And The Influence Of Individual Differences, Styliani Malkogeorgou

Masters

Students’ decisions to pursue education and careers in Science, Technology, Engineering, and Mathematics (STEM) are shaped by an interplay of cognitive, social, and motivational factors. Spatial ability is among the most reliable predictors of STEM success, yet less is known about how it relates to students’ STEM attitudes and aspirations, and whether visuospatial working memory (VSWM) explains this relationship. This study tested the hypotheses that (a) stronger spatial abilities and VSWM would be associated with more positive STEM attitudes and stronger STEM aspirations, and (b) VSWM would mediate the relationship between spatial abilities and STEM attitudes/aspirations, while examining the influence …

Ischemic Stroke As The Initial Presentation Of Advanced Pancreatic Adenocarcinoma: A Case Of Marantic Endocarditis., Micah Harris

Ambulatory and Primary Care Articles

Nonbacterial thrombotic endocarditis (NBTE), formerly known as marantic endocarditis, is a rare condition characterized by sterile vegetations on cardiac valves and is often associated with hypercoagulable states such as adenocarcinoma. We describe a patient who presented with multiple embolic cerebrovascular accidents, ultimately found to be secondary to NBTE, which served as the initial manifestation of previously undiagnosed advanced pancreatic adenocarcinoma. This case underscores the importance of considering NBTE in patients with multifocal embolic infarcts, particularly when blood cultures are negative, echocardiography reveals valvular abnormalities without evidence of infection, and clinical suspicion for an underlying malignancy is present.

Artificial Neural Network Model For Predicting Fatigue Endurance Limit Of Hot Mix Asphalt Using Uniaxial Tension–Compression Tests, Prashanta Kumar Acharjee, Mayzan Isied, Mena I. Souliman, Sameer Jung Karkl, Tanvir Ahmed, Gokhan Saygili

Civil Engineering Faculty Publications and Presentations

Fatigue is one of the major distresses occurring in asphalt concrete pavement. Repeated traffic loading causes escalated structural damage which results in the formation of cracks. There is a strain level below which the Hot Mix Asphalt goes under fatigue failure, and it is called endurance limit. In this study, a predictive model is developed to predict endurance limit strain values by using artificial neural network. Uniaxial tension-compression fatigue test results conducted under NCHRP Project 9–44 A were utilized in the model development process. An equation is also extracted from the model along which gives the exact values as the …

Transcriptomics And Metabolomics Analysis Reveal Cell Subpopulations Of Trophoblast Cells Associated With Preeclampsia, Xiaojun Zhu, Ying Jiang, Lilin Wang, Peiyue Jiang, Zixing Zhong, Hetong Li, Caihong Zheng, Lujiao Chen, Juan Wei, Xishi Lin, Peng Ding, Zehua Dong, Xiaosheng Wang, Qiong Luo

Faculty, Staff and Student Publications

Placental abnormalities are central to preeclampsia (PE), yet the cellular and molecular mechanisms underlying this dysfunction remain unclear. We applied a multi-layered, integrative approach to investigate placental tissue from patients with PE and matched controls. Single-cell RNA sequencing (scRNA-seq; GSE173193) and bulk RNA sequencing (bulk RNA-seq; GSE203507) datasets were obtained from the Gene Expression Omnibus. The scRNA-seq dataset included two PE and two control samples, whereas the bulk RNA-seq dataset focused on eight early-onset PE and five uncomplicated term births. Trophoblast subpopulations were identified via scRNA-seq, and pseudotime analysis was used to trace differentiation trajectories. Differential expression and pathway enrichment …

The Poly Problem In Zoning: Redefining "Family" For A Changing Society, Aric K. Short, Tanya Pierce

Faculty Scholarship

Single-family zoning has long dictated not only where people may live but also with whom. Although extensively critiqued for perpetuating racial and economic exclusion, these laws also privilege relationships defined by blood, marriage, or adoption and marginalize nontraditional families. This Article focuses on a particularly overlooked group: polyamorous families who often face legal uncertainty, social exclusion, and housing discrimination due to restrictive zoning definitions of “family.”

As polyamory gains cultural visibility and increasing legal recognition—through West 49th Street, LLC v. O’Neill and municipal reforms in cities like Somerville and Cambridge—now is the time to examine zoningÊs role in reinforcing outdated …

A Systemic Selective Modified Mrna Delivery Platform For Preventing Chemotherapy-Induced Cardiotoxicity, Jimeen Yoo, Mengcheng Shen, Et Al.

2020-Current year OA Pubs

Doxorubicin (Dox) is a widely employed chemotherapeutic agent, but its use is clinically limited by dose-accumulative cardiotoxicity. More specifically, Dox induces oxidative stress and causes pro-apoptotic ceramide accumulation in cardiomyocytes (CMs). Acid ceramidase (AC) modified mRNA (modRNA) has been shown to reduce ceramide levels and protect the heart following ischemic injury; however, therapeutic modRNA applications have been hindered by the need for invasive delivery. Here, we present a platform for minimally intrusive transmission of modRNA to the heart. This CM-selective modRNA translational system (cmSMRTs) is encapsulated in lipid nanoparticles for intravenous (IV) delivery to enable systemic administration with high cardiac …

Transforming Blood Management Systems In Developing Countries Through Technological And Artificial Intelligence-Driven Innovations, Sandeep Bhargava, Shaun Aaron Abram, Srividhya Ragavan

Faculty Scholarship

It is critical to ensure the safe and quality supply of blood among various stakeholders; however, this remains a significant challenge in today’s world, especially in developing countries. These countries face severe problems, including blood shortages, fragmented regulatory frameworks, and inconsistent quality control measures. To tackle these challenges, countries like India are trying to implement the use of artificial intelligence (AI) and its derivative platforms to transform blood collection, testing, storage, and distribution by enabling interoperability, real-time compliance monitoring, automated donor screening, optimized inventory management, and advanced component separation. The article argues that developing countries must adopt both regulatory reform …

Does Hormone Replacement Therapy Reduce Bone Resorption In Postmenopausal Women With An Intact Uterus?, Ashley Harding

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not hormone replacement therapy reduces bone resorption in postmenopausal women with an intact uterus.

STUDY DESIGN: A systematic review of three double blind randomized control trials (RCTs) published from 2016 to 2022.

DATA SOURCES: All RCTs were published in peer reviewed journals in English and were found on PubMed and Google Scholar. Articles were chosen based on relevance to the clinical question.

OUTCOME MEASURED: Level of bone resorption was measured via assessment of bone turnover markers at baseline and after use of hormone replacement therapy in all …

In Adults With Elevated Or Borderline-High Ldl Cholesterol Levels, Does Daily Consumption Of Oat-Derived Products Providing Approximately 3 G Of Β-Glucan Reduce Ldl Cholesterol?, Marilyn K. Enderson

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective evidence-based medicine review is to determine whether daily consumption of approximately 3 g of oat-derived β-glucan reduces low-density lipoprotein cholesterol (LDL-C) in adults with elevated or borderline-high LDL-C when compared with a β-glucan–free control.

STUDY DESIGN: Review of three double-blind randomized controlled trials (RCTs) published from 2020 to 2021.

DATA SOURCES: All RCTs were published in English in peer-reviewed journals and identified using PubMed. Articles were selected based on relevance to the clinical question, inclusion of adult populations with elevated LDL-C, and evaluation of oat-derived β-glucan as an intervention.

OUTCOMES MEASURED: The primary outcome …

Does A Single Dose Of Intravenous Ketamine Reduce Suicidal Ideation In Adults With Major Depressive Disorder?, Rylee Schieman

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not a “single dose of intravenous (IV) ketamine can decrease suicidal ideation in adults with major depressive disorder (MDD)?”

STUDY DESIGN: A systematic review of 3 double-blind, randomized controlled trials (RCTs) published from 2018 to 2024.

DATA SOURCES: All RCTs were found using PubMed and Google Scholar. The articles were published in peer-reviewed journals and in English. The articles were selected based on their relevance to the clinical question posed in the objective.

OUTCOMES MEASURED: All 3 studies focused on reducing suicidal ideation. The outcome was measured …

Hyaluronan 35 Prevents Endotoxin-Mediated Dysregulated Skeletal Muscle Proteostasis During Ethanol Exposure, Nicole Welch, Pugazhendhi Kannan, Gangarao Davuluri, Annette Bellar, Amy H. Attaway, Saurabh Mishra, Jasmin A. Cunningham, Avinash Kumar, Ryan Musich, Elif G. Ertugral, Vandana Agrawal, Isaac L. Hsu, Terri J. Harford, Noah L. Weisleder, Vidula T. Vachharajani, Chandrasekhar R. Kothapalli, Carol A. De La Motte, Laura E. Nagy, Srinivasan Dasarathy

Neurology Faculty Publications

Sarcopenia in alcohol-related liver disease (ALD) is of high clinical significance, but there are no effective treatments. Hyaluronan 35 kDa (HA35), a glycosaminoglycan polymer, modulates responses to Toll-like receptor 4 (TLR4), a lipopolysaccharide receptor, to improve hepatic and macrophage function in ALD. We evaluated skeletal muscle responses to HA35 in preclinical models of ALD. Responses to ethanol, lipopolysaccharide (LPS), and HA35 were studied in differentiated murine C2C12/human-induced pluripotent stem cell (hiPSC)-derived myotubes, and wild-type/HA receptor CD44 knockout (CD44^—/—) mouse models of ALD (mALD). Signaling molecules and measures of protein homeostasis (proteostasis) were quantified by immunoblots, mitochondrial oxidative function …

Efficiency Evaluation Of Different Methods For Nitrogen Removal In Municipal Wastewater Treatment Plants: An Integrative Review, Cristiane G. Ferrarezzi, Juliana Canto Duarte

The School of Sustainability Engineering and Environmental Engineering (SEE) Graduate Student Publications

Domestic wastewaters present high nitrogen levels due to the urea and ammonia, which are excreted into urine. Municipal wastewater treatment plants (WWTP) normally face some challenges in keeping their treated wastewater at a low total nitrogen concentration, since the majority of their wastewater is domestic. Low nitrogen levels in the treated wastewater are important to avoid increasing eutrophication of the receptor body, which receives the treated wastewater. This work presents an integrative review considering studies related to denitrification in domestic WWTPs published from January 1st, 2018, to April 30th, 2023. This review aims to identify the most effective methods for …

High Stakes Literacy Testing: Indiana’S Iread-3, Christy Wessel Powell, Karyn Tomkinson, Whitney Rippy

Science of Reading

Indiana is one of a few states to enact a high stakes literacy test in third grade, the IREAD-3 test. High stakes testing is often a useful way to ensure a particular level of academic proficiency is met to allow students to succeed in a new setting, like college, or leave high school with desired skills. However, the requirement to automatically retain third graders who do not pass the IREAD-3 test without additional information or considerations, is not supported by research (AERA, 2000). These data highlight the critical need for educators and administrators to understand high-stakes standardized tests, as they …

Diagnostic Limitations, Patient Characteristics, And Confounding Factors Impacting Neurotologic Lesion Imaging: A Systematic Review, Diana Hamdan, Precious Ochuwa Imokhai, Alexandra Konvalina, Baokhanh Nguyen, Maha Alhoda, Valentina Alejandra Da Silva Acosta, Waseem Syed, Amanda Brooks

Student Publications

Background: Neuroimaging protocols for neurotologic disease are often developed without consideration of patient-specific factors such as biological differences, clinical presentation variability, and comorbidities. This lack of tailored design contributes to insufficient detection, delayed diagnosis, and inappropriate treatment. Objectives: To critically examine the literature on diagnostic limitations of neuroimaging for neurotologic lesions and identify gaps in protocol validation, accuracy, and clinical translation. Methods: A systematic review of PubMed and Google Scholar was conducted, focusing on studies published between 2015 and 2025 that evaluated diagnostic imaging outcomes in patients with neurotologic lesions. Eligible studies included prospective cohorts, retrospective analyses, …

Supporting Data – Urban Stream, Cardinal Court, Isu, Normal, November 9, 2023 To May 1, 2025, Eric Wade Peterson, Ava Miller

Faculty Publications - Geography, Geology, and the Environment

Between November 9, 2023 to May 1, 2025, water samples were collected upstream and downstream along a segment of a stream adjacent to Cardinal Court on the Illinois State University campus. At each location, samples were collected at the surface. In-situ measurements of Dissolved Oxygen, Specific Conductance, and Temperature were recorded with a YSI 85. Anion samples were analyzed using a Ion Chromatograph for fluoride (F^-), chloride (Cl^-), nitrate as nitrogen (NO3-N), phosphate (PO₄^3-), and sulfate (SO₄^2-). The available dataset provides the recorded field parameters and the analyzed ion concentrations.

Anthelmintic Efficacy Of Rosemary Oil And Its Nanoemulsion Against The Monogenean Parasite, Zeuxapta Seriolae, In Yellowtail Kingfish (Seriola Lalandi), Md Reaz Chaklader, Lindsey Woolley, Hosna Gholipour-Kanani, Masashi Maita, Gavin Partridge

Fisheries Research Articles

This study evaluated the anthelmintic efficacy of rosemary oil delivered as a nanoemulsion compared with regular rosemary oil against the monogenean parasite Zeuxapta seriolae in yellowtail kingfish (YTK; Seriola lalandi). A 20-day feeding trial tested three dietary treatments: two levels of regular rosemary oil (providing 0.85 and 1.7 g cineole·kg−1 feed) and a rosemary-oil nanoemulsion (providing 0.85 g cineole·kg−1 feed), against a control diet without rosemary oil. Juvenile fish (293 ± 5 g) were pre-exposed to Z. seriolae oncomiracidia before the trial, resulting in an initial mean parasite abundance of 97 ± 4 per fish. At trial completion, plasma …

Medical Device Dangers: Choosing Ignorance In The Courts And At The Fda, George Horvath

William & Mary Law Review

Medical devices save lives and improve well-being but have caused as many as 83,000 deaths and 1.7 million injuries in a recent decade. Decisions of critical importance—patients’ decisions whether to have a device implanted, doctors’ decisions about which device to use, insurers’ decisions whether to reimburse for those devices—depend on information about risk that is provided by manufacturers. But producing this information is costly. Injured patients, through private lawsuits under state products liability theories, can incentivize device manufacturers to incur these costs and to produce and disclose information about device risk. Unfortunately, courts are making it increasingly unlikely that this …

Skrmetti And The Problem Of Incidental Intent, Martin Katz

William & Mary Law Review

The modern Supreme Court has defined “discriminatory intent” as a strict-liability concept. It does not matter why the government sorts people by a protected characteristic, such as race or sex; it matters only that the government does sort people by such a characteristic. This principle is the key holding of affirmative-action cases, such as Students for Fair Admissions, Inc. v. President & Fellows of Harvard College. Yet, in the recent case United States v. Skrmetti, the Court seemed to focus not on the question of whether the government sorted people by sex (it did), but on the question …

Interannual Variation In Seed Traits Of Cedrela Species, Guadalupe Galíndez, Ana Álvarez, Diana Ceccato, Victoria Rivero, Gisela Malagrina, Tania Bertuzzi, Pablo Saravia, Stavros Nicolás Sola, Carol C. Baskin, Luis Fornes

Plant and Soil Sciences Faculty Publications

Climate change is altering temperature and precipitation regimes in Argentina, with potential consequences for regeneration and persistence of forest tree species, emphasizing the importance of ex situ seed conservation. We evaluated interannual variation in seed traits, desiccation tolerance, storage behavior, and longevity of Cedrela balansae C. DC. and C. fissilis Vell. (Meliaceae), two endangered native species of subtropical rainforests in Argentina. Both species produced desiccation-tolerant seeds, independently of collection year, seed traits, or climatic conditions. Depending on the species, seed traits and longevity varied across years and showed strong relationships with temperature and precipitation, particularly during seed development. Cedrela balansae …

Synthetic Microbial Communities Enhance Tobacco Quality By Driving Bacterial Community Succession And Modulating Metabolite Profiles, Kuifu Men, Huaqiang Xuan, Jingrui Chen, Hongliang Li, Xuwei Chen, Yingle Jiao, Xianchao Shang, Yi Xie, Li Zhang, Long Yang, Ling Yuan, Sitakanta Pattanaik, Xin Hou

Plant and Soil Sciences Faculty Publications

The fermentation of cigar tobacco leaves (CTLs) is a critical process driven by microbial activity, which directly influences the degradation of macromolecules and the development of distinctive aromas. However, mechanisms for the directional regulation of this process using defined microbial consortia remain underexplored. This study aimed to construct a synthetic microbial community (SynCom) to enhance the fermentation efficiency and quality of cigar tobacco leaves. Bacillus safensis and Bacillus velezensis with high extracellular cellulase, amylase and protease activities were screened out, and synthetic communities were constructed. This microbial community was applied to cigar tobacco leaves (cultivar QX204) during a 42-day fermentation. …

Local Angiotensin Converting Enzyme 2 (Ace2) Enzymatic Activity Modulates Cholinergic Interneuron Function In The Dorsolateral Striatum, Aria R. Walls

Dissertations, Theses, and Capstone Projects

The renin angiotensin system (RAS) is an ancestrally ancient peptidergic signaling pathway best known for its role regulating blood pressure in the periphery. However, its presence and importance in the central nervous system has more recently been identified and is less well understood. Previous work shows RAS is expressed in the nigrostriatal pathway of the basal ganglia and has been implicated in basal ganglia disorders including Parkinson’s disease (PD) and levodopa-induced dyskinesia (LID). Interestingly, the canonical and noncanonical arms of the RAS pathway produce opposite effects on PD disease vulnerability and progression. The shift from the neurodegenerative canonical RAS to …

Monosaccharide Binding To Synthetic Carbohydrate Receptor Microarrays, Milan A. Shlain

Dissertations, Theses, and Capstone Projects

Chapter 1: A glycan detection platform comprised of synthetic carbohydrate receptors (SCRs) immobilized onto polymer brushes was prepared. SCR043, an alkene-containing SCR, was incorporated into grafted-from polymer brushes using hypersurface photolithography, resulting in microarrays of SCR043-functionalized polymer brushes, where brush height (h) and SCR grafting density (Γ) is controlled precisely at each feature in the array. The influence of h and Γ on the binding to five fluorescently labelled monosaccharides – α-glucose (α-Gluc-FL), α-galactose (α-Gal-FL), α-mannose (α-Man-FL), β-glucose (β-Gluc-FL), and β-galactose (β-Gal-FL) – in aqueous buffer …

Mechanistic Studies Of Aerobic Photochemistry: Gold Nanoclusters, Nanoparticles, And Solution-Phase Systems, Serah Essang

Dissertations, Theses, and Capstone Projects

This thesis comprises five chapters as enumerated below.

Chapter 1 describes our findings on the reactions of Au glutathione nanocluster (Au₂₀SG₁₆) with singlet oxygen (¹O₂) in D₂O. We noticed it underwent a self-photooxidation reaction. Leading us to mechanistic studies using photophysical, photochemical, theoretical, and indirect trapping methods. We found rapid total quenching of singlet oxygen (¹O₂) by ground-state Au₂₀(SG)₁₆, with evidence for dioxygen insertion into the nanocluster. Supported by analyses with IR, ESI-MS, and density functional theory, we propose the formation of …