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Comparative Antibacterial Efficacy Of Povidone-Iodine, Citric Acid, And Starch: A Study Of Combined Activity And Interference Effects Against Clinically Relevant Bacteria, Falah Hasan Obayes Al-Khikani, Mustafa Mutar Trrad, Ali Abedulameer Alhusayni Mar 2026

Comparative Antibacterial Efficacy Of Povidone-Iodine, Citric Acid, And Starch: A Study Of Combined Activity And Interference Effects Against Clinically Relevant Bacteria, Falah Hasan Obayes Al-Khikani, Mustafa Mutar Trrad, Ali Abedulameer Alhusayni

AUIQ Complementary Biological System

Povidone-iodine and citric acid are widely used antimicrobial agents. However, data on their comparative efficacy and the functional outcomes of their combination, particularly regarding the influence of common excipients like starch, is limited. Understanding these interactions is crucial for optimizing antiseptic formulations. This study aimed to evaluate and compare the antibacterial activity of povidone-iodine, citric acid (5% and 20%), and starch (5% and 20%), both individually and in combination, against clinical isolates of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. The antibacterial activity of the agents was assessed using an agar well diffusion assay. Mean inhibition zone …


Coalition Building In Art Education: Holding Space, Redistributing Weight And Witnessing, Kathy J. Brown, Beth Link, Kendall Crabbe, Cheryl Boone Mar 2026

Coalition Building In Art Education: Holding Space, Redistributing Weight And Witnessing, Kathy J. Brown, Beth Link, Kendall Crabbe, Cheryl Boone

Journal of Social Theory in Art Education

Our coalition is made up of four art educators working across institutions of higher education. After encountering various racialized critical incidents, we began meeting virtually and in-person, to imagine new ways of navigating academic spaces. We are all cis women, two of us identify as Black, 2 as white, with varied ages and positions in academic institutions across the country. We gathered after the surge of Black Lives Matter protests and in the wake of a global pandemic. We gathered amid political backlash in the south as anti-CRT and DEI legislation dominated educational landscapes and abortion rights were curtailed. We …


Segi Hukum Dalam Pengendalian Pencemaran Lingkungan Hidup, Soerjono Soekanto Mar 2026

Segi Hukum Dalam Pengendalian Pencemaran Lingkungan Hidup, Soerjono Soekanto

Jurnal Hukum & Pembangunan

Abstract


Optimizing 3d Printing Parameters For Pla And Petg: Advancing High-Quality Skull Implant Production, Reem Khzzal, Marwan Nafaa, Wisam Hamdan Mar 2026

Optimizing 3d Printing Parameters For Pla And Petg: Advancing High-Quality Skull Implant Production, Reem Khzzal, Marwan Nafaa, Wisam Hamdan

Engineering and Technology Journal

This study investigates the mechanical performance of 3D-printed polylactic acid and polyethylene terephthalate glycol materials by examining the effects of three crucial printing parameters (layer thickness, infill density, and infill pattern). Each material was tested mechanically for impact toughness, flexural strength, ductility, and ultimate tensile strength (UTS) using a Box-Behnken Design (BBD) to create 15 samples. The statistical significance of each parameter's impact was evaluated using ANOVA. The findings showed that, for PLA, layer thickness had no discernible impact on impact toughness (p = 0.726), while infill density (p = 0.031) and infill pattern (p = 0.049) had the most …


Parametric Evaluation And Biomechanical Assessment Of A Curved Biodegradable Zk60 Locking Plate For Femoral Shaft Fractures Using Finite Element Analysis, Ahmad Jasim, Jenan Kashan, Aseel Abed Mar 2026

Parametric Evaluation And Biomechanical Assessment Of A Curved Biodegradable Zk60 Locking Plate For Femoral Shaft Fractures Using Finite Element Analysis, Ahmad Jasim, Jenan Kashan, Aseel Abed

Engineering and Technology Journal

This study evaluates the biomechanical performance of a novel curved biodegradable ZK60 magnesium alloy locking plate for plate osteosynthesis in midshaft femoral fractures classified as AO/ASIF 32-A3 (Arbeitsgemeinschaft für Osteosynthesefragen/Association for the Study of Internal Fixation). Current metallic implants are associated with complications such as stress shielding, the need for secondary surgery, and limited support for biological healing. Biodegradable options offer promising solutions but remain insufficiently studied, especially regarding curved plate designs. This work addresses that gap by systematically assessing how plate thickness and curvature influence fracture stability. Finite element analysis (FEA) was performed under physiological loading of 700 N …


The Influence Of The Alkali-Treated Bamboo Particles On The Rubber Blend Properties For Medical Applications, Shaymaa Ahmed, Jawad Oleiwi, Qahtan Hamad Mar 2026

The Influence Of The Alkali-Treated Bamboo Particles On The Rubber Blend Properties For Medical Applications, Shaymaa Ahmed, Jawad Oleiwi, Qahtan Hamad

Engineering and Technology Journal

This study investigates the effect of chemical treatment on the mechanical properties of bamboo particle-reinforced grafted binary rubber blend systems (RTV-SIR/PUR), particularly for medical applications such as Solid Ankle Cashion heel (SACH) prosthetic feet. The Grafted binary rubber blend composite is consisting of Polyurethane (PUR) with (10, 20, and 30 wt.%) of Room temperature vulcanized silicone rubber (RTV-SIR) with presence of 0.1% of Tetraethoxysilane (TEOS) as coupling agent to more compatibility, and added different percentage of treated bamboo particles (3, 6, and 9 wt.%) that treated by 5% of Sodium Hydroxide (NaOH). The effectiveness of the alkali treatment in eliminating …


Enhancing Antibacterial Performance Of Powder Metallurgy-Fabricated Ti, Ti-15mo, And Ti-45zr Alloys Through Small Liquid Metal Gallium Additions In Biomedical Applications, Ammar Hasan, Fatimah Al‑Hasani, Emad Al‑Hassani Mar 2026

Enhancing Antibacterial Performance Of Powder Metallurgy-Fabricated Ti, Ti-15mo, And Ti-45zr Alloys Through Small Liquid Metal Gallium Additions In Biomedical Applications, Ammar Hasan, Fatimah Al‑Hasani, Emad Al‑Hassani

Engineering and Technology Journal

This study investigates the influence of small liquid metal gallium additions (1, 1.5, 2, and 2.5 wt%) on the antibacterial performance of Ti, Ti-15Mo, and Ti-45Zr alloys fabricated by the powder metallurgy method. The alloys were manufactured by sintering at 1250 °C to improve the antibacterial activity of Titanium and its alloys in biomaterial applications. X-ray diffraction (XRD) was used to identify the dominant compounds and phases after adding liquid gallium metal, and the antibacterial activity was also tested; the results indicate an increase in the Zone of inhibition of Ti, Ti-15Mo, and Ti-45Zr with increasing gallium/Ga content, where the …


Impact Of Sintering Time On Corrosion Rate And Relative Density Of Titanium, Titanium-Aluminum Alloy, And Titanium-Based Composites For Bio-Applications, Marwa Hadi, Niveen Abdulkader, Layth Al-Gebory Mar 2026

Impact Of Sintering Time On Corrosion Rate And Relative Density Of Titanium, Titanium-Aluminum Alloy, And Titanium-Based Composites For Bio-Applications, Marwa Hadi, Niveen Abdulkader, Layth Al-Gebory

Engineering and Technology Journal

The corrosion of implanted metals in the human body results in degradation and the release of harmful ions. Titanium and its alloys are used in biomedical applications due to their corrosion resistance and biocompatibility. This study examines how the amount of time spent sintering affects the density and corrosion resistance of Ti, Ti-6% Al, and Ti-6 % Al-2% HA (hydroxyapatite). Al was incorporated into Ti to reduce its density and enhance corrosion resistance. In contrast, HA was added at 2%, which aims to improve bioactivity and facilitate better integration with bone tissue. The samples were fabricated through powder metallurgy by …


Assessment And Surface Modeling Of Cod Removal From Simulated Dairy Wastewater In A Continuous Advanced Oxidation Reactor, Anwar Hashim, Mohammed Salman Mar 2026

Assessment And Surface Modeling Of Cod Removal From Simulated Dairy Wastewater In A Continuous Advanced Oxidation Reactor, Anwar Hashim, Mohammed Salman

Engineering and Technology Journal

The paper herein shows modeling and optimization of a continuous-flow ultraviolet/hydrogen peroxide (UV/H2O2) AOP to degrade chemical oxygen demand (COD) in simulated dairy wastewater. The common conventional treatment procedures, such as biological and physicochemical processes, may be limited by the high amount of sludge formation, high costs, and poor removal of recalcitrant organic contaminants that form. This research, therefore, aims to design a more effective photochemical treatment alternative by conducting experimental studies and developing a more accurate model. A tailor-made cubic photoreactor with double 6 W low-pressure UV lamps (254 nm) was used to investigate the effect of three parameters: …


Evaluating The Performance Of An Electrocoagulation Process Using Response Surface Methods For Textile Wastewater Treatment, Adedayo Badejo, Fidelis Nkeshita, Ayorinde Olanipekun, Babatunde Bada, Adekunle David, Julius Ndambuki, Williams Kupolati Mar 2026

Evaluating The Performance Of An Electrocoagulation Process Using Response Surface Methods For Textile Wastewater Treatment, Adedayo Badejo, Fidelis Nkeshita, Ayorinde Olanipekun, Babatunde Bada, Adekunle David, Julius Ndambuki, Williams Kupolati

Engineering and Technology Journal

The textile industry is one of the largest polluters of water resources, producing effluents containing complex mixtures of pollutants such as dyes, heavy metals, and high biological oxygen demand. Electrocoagulation (EC) is an efficient wastewater treatment technique that uses iron or aluminum electrodes to coagulate and adsorb pollutants. This work assesses the performance of EC for textile wastewater treatment to identify the best combination of pH (5-9), electrolysis time (20-60 min), and voltage (5-11 V) on Chemical Oxygen Demand (COD) and color removal. The results show that voltage and electrolysis time had a positive effect on the efficiencies of pollutant …


Progress Of Nanomaterials Incorporation Into Pvdf Membrane Distillation: Characteristics Enhancement, Nanomaterials Leaching And Stability: A Review, Samraa Khaleel, Salah Ibrahim, Raed Al-Juboori, Woei Lau, Siew Low, Zeinab Jawad, Saad Al-Saadi, Qusay Alsalhy Mar 2026

Progress Of Nanomaterials Incorporation Into Pvdf Membrane Distillation: Characteristics Enhancement, Nanomaterials Leaching And Stability: A Review, Samraa Khaleel, Salah Ibrahim, Raed Al-Juboori, Woei Lau, Siew Low, Zeinab Jawad, Saad Al-Saadi, Qusay Alsalhy

Engineering and Technology Journal

Membrane distillation (MD) faces challenges in the form of diminished permeate flux attributed to the loss of hydrophobicity with time. Nanomaterials play an essential role in enhancing the performance of MD through membrane modification during formation or surface modification. Numerous nanomaterials have been investigated, particularly for flat sheet polyvinylidene fluorides (PVDF). These nanomaterials have provided unparalleled opportunities for the MD process application, such as increased water desalination efficiency, improved membrane durability, and reduced energy consumption. Adding nanomaterials changed the MD membrane properties, such as the size of the pores, porosity, and hydrophobicity, which significantly enhanced MD efficiency. However, some are …


A Review Of Smart Actuation Technologies In Modern Mechatronic Systems, Ivan Gorial Mar 2026

A Review Of Smart Actuation Technologies In Modern Mechatronic Systems, Ivan Gorial

Engineering and Technology Journal

Smart actuation has transformed mechatronics over the past six years by harnessing materials that turn heat, electricity, magnetism, or light into finely tuned motion. Our survey of developments from 2019 to 2025 reveals clear trade-offs: electro-active polymers can stretch beyond 200% but operate at roughly 30% efficiency, whereas piezoelectric devices achieve over 95% efficiency with displacements under 0.1%. Ionic polymer–metal composites and magnetorheological actuators strike the best balance for precision work, delivering about 50% stroke at 60% efficiency. Real-world examples show that packing tiny shape-memory alloy bundles into soft exosuits grants sub-millimeter accuracy without sacrificing comfort, and that materials capable …


Experimental Adsorption Of Drug Loading For Nano-Carriers, Hind Abbood, Alaa Abdul-Hamead, Farhad Othman Mar 2026

Experimental Adsorption Of Drug Loading For Nano-Carriers, Hind Abbood, Alaa Abdul-Hamead, Farhad Othman

Engineering and Technology Journal

This study focuses on preparing and characterizing mesoporous silica nanoparticles (MSNs) with two distinct pore sizes: small and large. The MSNs were employed to encapsulate paclitaxel (PTX), achieving enhanced drug-loading capacity and improved cytotoxicity. The MSNs synthesis by modified sol-gel method and the pore size can be modified by adding the mesitylene to MSNs for 1, 3, and 5hr. The drug loading was carried out by dissolving the PTX drug with different solvents, water, ethanol, DMSO, and dichloromethane by the Adsorption method and measuring the drug loading capacity and drug loading efficiency for both types of mesoporous silica nanoparticles. All …


Treatment For Dairy Waste Water Using A Photoreactor (Uv And Hydrogen Peroxide) As An Alternative Treatment Technique, Anwar Hashim, Hala Abdulkareem, Mohammed Salman Mar 2026

Treatment For Dairy Waste Water Using A Photoreactor (Uv And Hydrogen Peroxide) As An Alternative Treatment Technique, Anwar Hashim, Hala Abdulkareem, Mohammed Salman

Engineering and Technology Journal

The contamination of vital life supplies by industrial waste, especially dairy effluent, is a growing global concern. This study investigates the impact of advanced oxidation processes (AOP) on treating dairy wastewater utilizing UV/H2O2 AOP. Utilized ultraviolet lamps in conjunction with hydrogen peroxide oxidant reagent (0.6, 1.2, 1.8, and 2.4 ml/L) in batch experiments under varying parameters to optimize the treatment of dairy wastewater before and following its introduction to the advanced oxidation process (AOP) system, by measuring Biological Oxygen Demand (BOD) and Chemical Oxygen Demand (COD). The impacts of varying circulation durations in a photocatalytic system (60-360 minutes), flow rates …


Impact Of Laser Energy On The Synthesis And Antibacterial Performance Of Cdo Nanomaterials, Ali Yousif, Thikra Mejbel, Kadhim Aadim, Wasan Kadhem Mar 2026

Impact Of Laser Energy On The Synthesis And Antibacterial Performance Of Cdo Nanomaterials, Ali Yousif, Thikra Mejbel, Kadhim Aadim, Wasan Kadhem

Engineering and Technology Journal

The objective of the current work is to evaluate the antibacterial efficiency of cadmium oxide nanomaterials (CdO NPs) produced through pulsed laser ablation in liquid (PLAL) with laser energy ranging from 400 to 600 mJ. Several characterization techniques, including X-ray diffraction (XRD), UV-Vis spectroscopy, and atomic force microscopy (AFM), were harnessed to analyze synthesized CdO NPs. The nanoparticles had a spherical shape and a size distribution that reduced with higher laser energy. The XRD study confirmed a polycrystalline cubic structure, while AFM measurements disclosed a drop from 133 to 84 nm in the particle size as laser intensity rose. UV-Vis …


Investigation Of Fe3o4 Nanoparticles Synthesized Via Co-Precipitation Coated With Chitosan, Peg, And Folate For Targeted Paclitaxel Delivery In Fibrosarcoma Treatment, Adawiya Haider, Sharafaldin Al-Musawi, Rusul Al-Obaidy, Azhar Haleemd, Mohammed Al-Hindawi, Bakr Taha Mar 2026

Investigation Of Fe3o4 Nanoparticles Synthesized Via Co-Precipitation Coated With Chitosan, Peg, And Folate For Targeted Paclitaxel Delivery In Fibrosarcoma Treatment, Adawiya Haider, Sharafaldin Al-Musawi, Rusul Al-Obaidy, Azhar Haleemd, Mohammed Al-Hindawi, Bakr Taha

Engineering and Technology Journal

Magnetite (Fe3O4) nanoparticles (NPs) were synthesized using a straightforward co-precipitation method from Fe2+/Fe3+ salt solutions as starting materials. This method was optimized to control particle size and morphology, resulting in highly magnetic NPs with crystallite sizes ranging from 20 to 70 nm. The synthesis process involved magnetic stirring at 700 rpm at room temperature, yielding approximately 5 mg of Fe3O4 powder. Structural characterization via X-ray diffraction (XRD) confirmed the stoichiometric composition and particle dimensions. To enhance functionality, the Fe3O4 NPs were coated with chitosan (Cs), polyethylene glycol (PEG), and folic acid (FA), and loaded with the anticancer drug paclitaxel (PTX), …


Enhancing The Removal Of Total Dissolved Solids From Petroleum Wastewater Through Electrocoagulation, Muhammad Jasim, Forat Aljaberi, Saja Alardhi, Ali Salman, Mustafa Hathal, Igor Cretescu, Armando Vargas Mar 2026

Enhancing The Removal Of Total Dissolved Solids From Petroleum Wastewater Through Electrocoagulation, Muhammad Jasim, Forat Aljaberi, Saja Alardhi, Ali Salman, Mustafa Hathal, Igor Cretescu, Armando Vargas

Engineering and Technology Journal

This study aims to employ an electrocoagulation reactor to treat petroleum effluent from a local plant and reduce dissolved solids (TDS) to suitable levels for reuse. A continuous reactor configuration featured a finned stainless steel cathode tube positioned between two cylindrical aluminum anodes. This study explored the influence of treatment duration (4–60 minutes), current density (0–6.0 mA.cm-2), and influent rate (50–150 ml/min) on the final TDS value. Flow rate increase correlated with increased final TDS values, while longer electrolysis durations and higher current densities led to decreased TDS levels. Optimized electrolysis conditions at 1 hour, 5 mA.cm-2, and 50 ml/min, …


Experimental And Theoretical Study To Improve Heat Transfer Using Nanofluids Flow In Copper Tube, Zahraa Hussain, Jamal Ali, Hasan Majdi, Abbas Sultan, Bashar Kadhim, Haidar Al-Naseri Mar 2026

Experimental And Theoretical Study To Improve Heat Transfer Using Nanofluids Flow In Copper Tube, Zahraa Hussain, Jamal Ali, Hasan Majdi, Abbas Sultan, Bashar Kadhim, Haidar Al-Naseri

Engineering and Technology Journal

Improving heat transfer efficiency in base fluids remains a key challenge in various thermal applications. To address this, several researchers have suggested the integration of nanoparticles into base fluids, leveraging recent advancements in nanotechnology to enhance performance. This study compares different types of nanoparticles and preparation methods for nanofluids and examines the impact of their properties on improving heat transfer. The convective heat transfer under a turbulent flow regime was studied experimentally and numerically in a copper tube used as a test section. Advanced measurement techniques were employed, including a Flux Teq LLC heat flux sensor mounted on the test …


The Factors Affecting Anticancer, Antibacterial, And Photocatalytic Applications Of Zno Nanocomposite Synthesized By Plal: A Mini Review, Huda Al-Attar, Maeda Mohammad, Basma Bedair Mar 2026

The Factors Affecting Anticancer, Antibacterial, And Photocatalytic Applications Of Zno Nanocomposite Synthesized By Plal: A Mini Review, Huda Al-Attar, Maeda Mohammad, Basma Bedair

Engineering and Technology Journal

Fresh water is essential for life to continue on Earth. The accelerated growth of industrialization and globalization is to blame for the current apex of environmental problems. Heavy metals and organic pollutants discharged from industrial waste are extremely harmful at relatively minimal concentrations when tolerance levels are exceeded. They will lead to several diseases in humans. One method for treating wastewater is semiconductor photocatalysis. It depends mainly on the oxidation-reduction mechanism by holes and electrons, respectively, that are generated by the exposure of the semiconductor oxide into a source of photons. Pulsed laser ablation in liquid (PLAL) has attracted significant …


An Exhaustive Review Of Carbon Dioxide Capture Through The Utilization Of Chemical Solvents Via Absorption, Hala Al-Maaine, Naseer Alhaboubi Mar 2026

An Exhaustive Review Of Carbon Dioxide Capture Through The Utilization Of Chemical Solvents Via Absorption, Hala Al-Maaine, Naseer Alhaboubi

Engineering and Technology Journal

The release of carbon dioxide from the combustion of fossil fuels and chimney emissions has emerged as the primary catalyst for global warming. The significant increase in emissions is due to various factors, including power plants that rely on fossil fuels, different industrial processes, and many other factors, all of which are the main causes of environmental pollution. The need has arisen to invent an effective way to reduce carbon dioxide emissions into the atmosphere, where scientists have reviewed several methods, such as transitioning to renewable energy, improving energy generation stations, and capturing carbon dioxide emissions. However, the optimal and …


The Phoenix Trauma Response Model (Ptrm): An Integrative And Innovative Approach To Trauma Recovery And Growth, Latesha S. Holloman, Lauren B. Robins, Tammie Willis, Courtney V. Morris Mar 2026

The Phoenix Trauma Response Model (Ptrm): An Integrative And Innovative Approach To Trauma Recovery And Growth, Latesha S. Holloman, Lauren B. Robins, Tammie Willis, Courtney V. Morris

Journal of Human Services Scholarship and Interprofessional Collaboration

Trauma is increasingly understood as a developmentally consequential experience that shapes identity, regulation, and relational functioning across the lifespan. Although trauma-informed care, resilience theory, posttraumatic growth, and narrative approaches have expanded understanding of recovery, few frameworks articulate a structured developmental progression that integrates prevention, intervention, and intergenerational transformation within a unified model. The Phoenix Trauma Response Model (PTRM) addresses this gap by introducing a cyclical, phase-based framework organized around four interrelated processes: Recognition, Reframing, Reclamation, and Replication of Strength. Central to the model is the construct of conversion potential, defined as the structured capacity to translate distress into purposeful …


Section Iii -- College Of Liberal Arts Policies And Procedures (Updated 03/02/2026), All Faculty Mar 2026

Section Iii -- College Of Liberal Arts Policies And Procedures (Updated 03/02/2026), All Faculty

Faculty Handbooks

No abstract provided.


Spectroscopy And Photochemistry Of The Astrochemical Molecules Sicp And Alcp, Vincent J. Esposito, Tarek Trabelsi, Rebecca Firth, Ryan C. Fortenberry, Joseph S. Francisco Mar 2026

Spectroscopy And Photochemistry Of The Astrochemical Molecules Sicp And Alcp, Vincent J. Esposito, Tarek Trabelsi, Rebecca Firth, Ryan C. Fortenberry, Joseph S. Francisco

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Through characterization of the electronic excited-state topology, linear-SiCP is predicted to be photostable in the UV region, whereas linear-AlCP is predicted to undergo photodissociation to form Al+CP products after absorption of light in the 200–250 nm range, representing a catalytic process for freeing aluminum molecules from a solid dust grain. Both SiCP and AlCP are predicted to have electronic transitions with large absorption cross sections (∼10–17 cm2) and to undergo fluorescence from bound excited states. The total electronic absorption spectrum is provided to inform electronic spectroscopy experiments. Silicon (SiC) and aluminum (Al2O3) dust …


Ifn Signaling Is Associated With Radiotherapy Response In Malignant Peripheral Nerve Sheath Tumors., Iowis Zhu, Julian Chien, Gabriel E Rech, Kanish Mirchia, Sixuan Pan, Kaeli Miller, Joanna Pak, Rosanna Wustrack, Varun Monga, Steve E Braunstein, Mark D Adams, Line Jacques, Melike Pekmezci, S John Liu, Harish N Vasudevan Mar 2026

Ifn Signaling Is Associated With Radiotherapy Response In Malignant Peripheral Nerve Sheath Tumors., Iowis Zhu, Julian Chien, Gabriel E Rech, Kanish Mirchia, Sixuan Pan, Kaeli Miller, Joanna Pak, Rosanna Wustrack, Varun Monga, Steve E Braunstein, Mark D Adams, Line Jacques, Melike Pekmezci, S John Liu, Harish N Vasudevan

Faculty Research 2026

Patients with malignant peripheral nerve sheath tumors (MPNSTs) have poor outcomes despite multimodal treatment with surgery, radiation, and systemic therapy. The responses to radiotherapy (RT) are mixed, and the biologic mechanisms underlying this heterogeneity in the radiation response of MPNSTs are not understood. Here, we combined bulk and single-cell transcriptomics, genome-wide CRISPR interference screens, and multiplatform molecular analysis across MPNST cells, mouse allograft models, and patients' samples to understand the mediators of the radiation response. Our data revealed that MPNSTs, but not benign plexiform neurofibromas, induced a type I IFN signature that functionally mediated the radiation response. Moreover, irradiation of …


Ifn Signaling Is Associated With Radiotherapy Response In Malignant Peripheral Nerve Sheath Tumors., Iowis Zhu, Julian Chien, Gabriel E Rech, Kanish Mirchia, Sixuan Pan, Kaeli Miller, Joanna Pak, Rosanna Wustrack, Varun Monga, Steve E Braunstein, Mark D Adams, Line Jacques, Melike Pekmezci, S John Liu, Harish N Vasudevan Mar 2026

Ifn Signaling Is Associated With Radiotherapy Response In Malignant Peripheral Nerve Sheath Tumors., Iowis Zhu, Julian Chien, Gabriel E Rech, Kanish Mirchia, Sixuan Pan, Kaeli Miller, Joanna Pak, Rosanna Wustrack, Varun Monga, Steve E Braunstein, Mark D Adams, Line Jacques, Melike Pekmezci, S John Liu, Harish N Vasudevan

Faculty Research 2026

Patients with malignant peripheral nerve sheath tumors (MPNSTs) have poor outcomes despite multimodal treatment with surgery, radiation, and systemic therapy. The responses to radiotherapy (RT) are mixed, and the biologic mechanisms underlying this heterogeneity in the radiation response of MPNSTs are not understood. Here, we combined bulk and single-cell transcriptomics, genome-wide CRISPR interference screens, and multiplatform molecular analysis across MPNST cells, mouse allograft models, and patients' samples to understand the mediators of the radiation response. Our data revealed that MPNSTs, but not benign plexiform neurofibromas, induced a type I IFN signature that functionally mediated the radiation response. Moreover, irradiation of …


Jax Animal Behavior System (Jabs), A Genetics-Informed, End-To-End Advanced Behavioral Phenotyping Platform For The Laboratory Mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, Vivek Kumar Mar 2026

Jax Animal Behavior System (Jabs), A Genetics-Informed, End-To-End Advanced Behavioral Phenotyping Platform For The Laboratory Mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, Vivek Kumar

Faculty Research 2026

Automated detection of complex animal behavior remains a challenge in neuroscience. Developments in computer vision have greatly advanced automated behavior detection and allow high-throughput preclinical and mechanistic studies. An integrated hardware and software solution is necessary to facilitate the adoption of these advances in the field of behavioral neurogenetics, particularly for non-computational laboratories. We have published a series of papers using an open field arena to annotate complex behaviors such as grooming, posture, and gait as well as higher-level constructs such as biological age and pain. Here, we present our integrated rodent phenotyping platform, JAX Animal Behavior System (JABS), to …


Jax Animal Behavior System (Jabs), A Genetics-Informed, End-To-End Advanced Behavioral Phenotyping Platform For The Laboratory Mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, Vivek Kumar Mar 2026

Jax Animal Behavior System (Jabs), A Genetics-Informed, End-To-End Advanced Behavioral Phenotyping Platform For The Laboratory Mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, Vivek Kumar

Faculty Research 2026

Automated detection of complex animal behavior remains a challenge in neuroscience. Developments in computer vision have greatly advanced automated behavior detection and allow high-throughput preclinical and mechanistic studies. An integrated hardware and software solution is necessary to facilitate the adoption of these advances in the field of behavioral neurogenetics, particularly for non-computational laboratories. We have published a series of papers using an open field arena to annotate complex behaviors such as grooming, posture, and gait as well as higher-level constructs such as biological age and pain. Here, we present our integrated rodent phenotyping platform, JAX Animal Behavior System (JABS), to …


Surgical Removal Of Visceral Adipose Tissue Has Therapeutic Benefit In Male Appnl-F Mice, Samuel A. Mcfadden, Yimin Fang, Kathleen Quinn, Mackenzie R. Peck, Jenelle E. Chapman, Tiarra Hill, Andrzej Bartke, Erin R. Hascup, Kevin Hascup Mar 2026

Surgical Removal Of Visceral Adipose Tissue Has Therapeutic Benefit In Male Appnl-F Mice, Samuel A. Mcfadden, Yimin Fang, Kathleen Quinn, Mackenzie R. Peck, Jenelle E. Chapman, Tiarra Hill, Andrzej Bartke, Erin R. Hascup, Kevin Hascup

Articles

Purpose:  Visceral white adipose tissue (vWAT) accumulation causes systemic inflammation, insulin resistance, metabolic syndrome, and senescent cell accumulation that are risk factors for Alzheimer’s disease (AD). Visceral fat removal (VFR) improves metabolism and reduces pro-inflammatory cytokines.  We hypothesized that VFR removal in AD mice would improve metabolism and cognition.

Methods:  Male and female APPNL-F mice underwent sham or vWAT surgical resection (periovarian or epididymal and perirenal) at 4 (pre-symptomatic) and 16 (symptomatic) months of age to understand interventional and therapeutic effects, respectively.  At 18 months of age, glucose metabolism and novel object recognition (NOR) memory were assayed followed by …


Rising Sun: The Musical Legacy Of Clarence "Tom" Ashley, The Reece Museum, East Tennessee State University Mar 2026

Rising Sun: The Musical Legacy Of Clarence "Tom" Ashley, The Reece Museum, East Tennessee State University

The Reece Museum Exhibition Publications

Clarence “Tom” Ashley (September 29, 1895 - June 2, 1967) was a musician from Mountain City, Tennessee. Ashley began making music at medicine shows and local fiddlers’ conventions as early as 1911. Notably, Ashley participated in the Mountain City Fiddlers Convention in May 1925, an event that is considered to have helped launch the modern country music industry by catching the attention of recording executives in the years leading up to the historic Bristol Sessions (1927-1928) and Johnson City Sessions (1928-1929). Ashley was recorded during the historic 1929 Johnson City Sessions as both a solo artist and as a member …


If We Build It, Will They Use It? Aligning Resource Recovery Design With Place-Based Social Systems, Jayce Sudweeks, Helen Rosko, Matthew R. Landsman, Francisco Cubas-Suazo, Lewis Stetson Rowles Mar 2026

If We Build It, Will They Use It? Aligning Resource Recovery Design With Place-Based Social Systems, Jayce Sudweeks, Helen Rosko, Matthew R. Landsman, Francisco Cubas-Suazo, Lewis Stetson Rowles

Public & Nonprofit Studies: Faculty Publications

Recovering water, nutrients, energy, and critical materials from waste streams is essential for building resilient and circular water systems. Yet many recovery technologies fail to achieve adoption or persistence beyond pilot scales because they overlook the social and institutional contexts that shape implementation. This Perspective reframes resource recovery as an adaptive challenge, i.e., one that depends as much on governance capacity, trust, and collective learning as on technical optimization. We propose a watershed- and place-based framework that situates recovery systems within the ecological and institutional boundaries where communities, infrastructure, and governance intersect. Within this discussion, the Community Capitals Framework offers …