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Expert Panel Process For Advanced Septic System Technologies, Fb Environmental Associates, Forrest Bell, Cayce Dalton, Bina Skordas, Luke Frankel, Magdalyn Kosalek, Evan Ma Sep 2023

Expert Panel Process For Advanced Septic System Technologies, Fb Environmental Associates, Forrest Bell, Cayce Dalton, Bina Skordas, Luke Frankel, Magdalyn Kosalek, Evan Ma

PREP Reports & Publications

No abstract provided.

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Enhanced Cell Viability And Migration Of Primary Bovine Annular Fibrosus Fibroblast-Like Cells Induced By Microsecond Pulsed Electric Field Exposure, Prince M. Atsu, Connor Mowen, Gary L. Thompson Iii Sep 2023

Enhanced Cell Viability And Migration Of Primary Bovine Annular Fibrosus Fibroblast-Like Cells Induced By Microsecond Pulsed Electric Field Exposure, Prince M. Atsu, Connor Mowen, Gary L. Thompson Iii

Henry M. Rowan College of Engineering Departmental Research

This study is the first to report the enhancement of cell migration and proliferation induced by in vitro microsecond pulsed electric field (μsPEF) exposure of primary bovine annulus fibrosus (AF) fibroblast-like cells. AF primary cells isolated from fresh bovine intervertebral disks (IVDs) are exposed to 10 and 100 μsPEFs with different numbers of pulses and applied electric field strengths. The results indicate that 10 μs-duration pulses induce reversible electroporation, while 100 μs pulses induce irreversible electroporation of the cells. Additionally, μsPEF exposure increased AF cell proliferation up to 150% while increasing the average migration speed by 0.08 μm/min over 24 …

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Pspa-Mediated Aggregation Protects Streptococcus Pneumoniae Against Desiccation On Fomites, Jessica R. Lane, Muralidhar Tata, Rahena Yasmin, Hansol Im, David E. Briles, Carlos J. Orihuela Sep 2023

Pspa-Mediated Aggregation Protects Streptococcus Pneumoniae Against Desiccation On Fomites, Jessica R. Lane, Muralidhar Tata, Rahena Yasmin, Hansol Im, David E. Briles, Carlos J. Orihuela

APC Fund

Streptococcus pneumoniae (Spn) resides in the nasopharynx where it can disseminate to cause disease. One key Spn virulence factor is pneumococcal surface protein A (PspA), which promotes survival by blocking the antimicrobial peptide lactoferricin. PspA has also been shown to mediate attachment to dying epithelial cells in the lower airway due to its binding of cell surface-bound mammalian (m)GAPDH. Importantly, the role of PspA during colonization is not well understood. Wildtype Spn was present in nasal lavage elutes collected from asymptomatically colonized mice at levels ∼10-fold higher that its isogenic PspA-deficient mutant (ΔpspA). Wildtype Spn also …

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Nonlinear Inverse Boundary Value Problem For A Second Order Parabolic Equation With Nonlocal Boundary Conditions, Academy Of Public Administration Under The President Of The Republic Of Azerbaijan, E.I. Azizbayov, Baku State University, Yashar Mehraliyev Sep 2023

Nonlinear Inverse Boundary Value Problem For A Second Order Parabolic Equation With Nonlocal Boundary Conditions, Academy Of Public Administration Under The President Of The Republic Of Azerbaijan, E.I. Azizbayov, Baku State University, Yashar Mehraliyev

Baku Mathematical Journal

The paper studies the classical solvability of an inverse boundary value problem for a second order parabolic equation with nonlocal boundary conditions. For this purpose, first, the considered problem is reduced to an auxiliary equivalent problem in a certain sense. Then, using the Fourier method the auxiliary problem is presented as a system of integral equations. Further, by means of the contraction mappings principle the unique existence of the solution of the obtained system of integral equations is shown. At the end of investigation the existence and uniqueness theorem for the classical solution of the original inverse boundary value problem …

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Operating Fund Budget/ Expenditure Detail Report 2023-24, Csusb Budget Office Sep 2023

Operating Fund Budget/ Expenditure Detail Report 2023-24, Csusb Budget Office

University Budget Office records

No abstract provided.

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Chanticleer | September 2023, Jacksonville State University Sep 2023

Chanticleer | September 2023, Jacksonville State University

Chanticleer

No abstract provided.

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Noticing Instructional Challenges In Artifacts Of Teaching, Tara Barnhart, Elizabeth Van Es Sep 2023

Noticing Instructional Challenges In Artifacts Of Teaching, Tara Barnhart, Elizabeth Van Es

Education Faculty Articles and Research

This study investigates challenges of enactment teachers notice when analyzing artifacts of teaching in a professional development focused on supporting the enactment of NGSS-aligned modeling instruction. Five secondary science teachers participated in a semester-long video club. Transcripts of the segments of their meetings in which they analyzed artifacts of practice were coded to characterize what they noticed in videos and student work samples from their own and others’ classrooms of students engaging in sensemaking. Through an inductive and iterative approach, three main linguistic challenges were identified related to the teachers’ noticing of students’ disciplinary thinking: learning how to communicate with …

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The Impact Of (Trx) Exercises On Developing Certain Physical Abilities For Performing Various Attacks In The Foil Fencing Sport For Female Players Under 20 Years’ Old, Reem Mohammed Abdul-Wahhab, Israa Fouad Salih Sep 2023

The Impact Of (Trx) Exercises On Developing Certain Physical Abilities For Performing Various Attacks In The Foil Fencing Sport For Female Players Under 20 Years’ Old, Reem Mohammed Abdul-Wahhab, Israa Fouad Salih

Modern Sport

The issue of learning and continuously and effectively training skills has become very challenging, especially for individuals under the age of (20). Therefore, the researchers decided to diagnose specific problems based on their expertise in the field. It led them to use (TRX) ropes, which can be easily used anywhere, to physically train the players to address the research problem, which is the weakness of physical abilities that directly affect their performance in various attacks. The study aimed to prepare (TRX) exercises for the research sample and explore the impact of (TRX) exercises on significant certain physical abilities and the …

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Genotype × Environment Interaction For Fibre Quality And Yield Related Traits Under Climatic Conditions Of Dera Ghazi Khan Division, Irum Aziz, Wajad Nazeer, Muhammad Faheem, Maria Basheer, Ali Bukhsh, Nouman Bilal Sep 2023

Genotype × Environment Interaction For Fibre Quality And Yield Related Traits Under Climatic Conditions Of Dera Ghazi Khan Division, Irum Aziz, Wajad Nazeer, Muhammad Faheem, Maria Basheer, Ali Bukhsh, Nouman Bilal

Journal of Bioresource Management

Cotton (Gossypium hirsutum L.) is a fibre and oilseed crop and offers raw materials to industries and livelihood for the rural poor. During the last decade, climate change has negatively affected crop production all over the world. Under such scenarios of climate change, plant breeders must explore the genetics of crops for better yield and fibre quality. Considering the extent of cotton in Pakistan's economy, the present research was planned to evaluate six cotton varieties in different locations for yield stability. Six varieties namely IUB-13, CIM-600, S-32, FH-Lalazar, CIM-616 and Z-33 were surveyed at farmer fields in Rajan Pur, …

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Extraction And Characterization Of Fibres From The Bark Of Ficus Nekbudu Tree, Liberato V Haule Sep 2023

Extraction And Characterization Of Fibres From The Bark Of Ficus Nekbudu Tree, Liberato V Haule

Tanzania Journal of Engineering and Technology (TJET)

This paper investigates the extraction and characterization of fibres from the bark of the ficus nekbudu tree. The Ficus Nekbudu Fibres (FNF) was extracted from the bark by retting in water and then treatment with sodium hydroxide solution. The extracted FNF was analysed for chemical composition, physical, tensile, surface, structural and thermal stability properties. Findings on the chemical composition indicated that FNF has cellulose (49.9 %), lignin (13.4%), ash (7.1%) and water content (8.1%). From the physical investigation it was found that FNF has density (1.42 ± 0.005 g/cm3) and moisture regain (9.2 ±0.3%). From mechanical investigation it was found …

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The Effect Of Tabata Exercises On The Development Of Stamina And Achievement For Female Athletes Running 100m Hurdles Under The Age Of 18 Years, Lamyaa Ayad Kareem, Zainab Qahtan Abdul-Mohsen Sep 2023

The Effect Of Tabata Exercises On The Development Of Stamina And Achievement For Female Athletes Running 100m Hurdles Under The Age Of 18 Years, Lamyaa Ayad Kareem, Zainab Qahtan Abdul-Mohsen

Modern Sport

The science of modern sports training is a scientific educational process based on sound foundations, and its goal is for the players to reach integration in the technical performance. And devices to achieve high sporting achievements, and the two researchers used a modern method of sports training methods in order to develop strength endurance and achievement for the 100m hurdles event female players under 18 years old. The importance of the study lies in the use of Tabata exercises, which are among the modern exercises that are characterized by suspense and excitement, and their application according to specific times in …

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The Effect Of Rehabilitative Exercises Preceded By An Electrical Stimulation Device For Working Muscles In Relieving Lower Back Pain For Women Aged (25-35) Years, Anaam Jaafar Sadiq, Bushra Kadhim Abdul-Ridha Sep 2023

The Effect Of Rehabilitative Exercises Preceded By An Electrical Stimulation Device For Working Muscles In Relieving Lower Back Pain For Women Aged (25-35) Years, Anaam Jaafar Sadiq, Bushra Kadhim Abdul-Ridha

Modern Sport

The importance of the research lies in: The effect of rehabilitative exercises accompanying the electrical stimulation device for working muscles in relieving lower back pain for women aged (25-35) years and identifying the extent of the effect of these exercises in relieving lower back pain. The research problem lies as a result of technological progress, as the individual's movement became less and less, which made him\her more vulnerable to injuries, which led to an increase in the number of women with lower back pain, and the negative effects of those pains on their practical and psychological lives, which prompted the …

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Exploring The Correlation Between Metacognitive Skills And Cognitive Learning Outcomes Across Various Biology Learning Models In High Schools, Ninik Kristiani, Herawati Susilo, Aloysius Duran Corebim, Fatchur Rohman Sep 2023

Exploring The Correlation Between Metacognitive Skills And Cognitive Learning Outcomes Across Various Biology Learning Models In High Schools, Ninik Kristiani, Herawati Susilo, Aloysius Duran Corebim, Fatchur Rohman

Jurnal Pendidikan Sains

In Malang City, a notable observation within the realm of high school biology education suggests a prevalent lack of metacognitive knowledge among teachers, hindering their efficacy in nurturing students' metacognitive capacities. Such deficiency yields implications for diminished cognitive abilities among students. Recognizing this, there emerges a pressing need for an enhanced pedagogical framework capable of fostering metacognitive skills adeptly. One promising approach involves integrating inquiry-based learning and problem- based mindful pedagogy (PBMP). This amalgamation is anticipated to synergistically harness the potential of both methodologies in bolstering metacognitive skills alongside cognitive learning outcomes. This study adopts a correlational research design, wherein …

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Analysis And Unraveling Misconceptions: Examining Tenth-Grade High School Students’ Errors In Hots Questions On Exponential Equations And Effective Scaffolding Strategies, Nunik Indayani, Erry Hidayanto, Sisworo Sisworo Sep 2023

Analysis And Unraveling Misconceptions: Examining Tenth-Grade High School Students’ Errors In Hots Questions On Exponential Equations And Effective Scaffolding Strategies, Nunik Indayani, Erry Hidayanto, Sisworo Sisworo

Jurnal Pendidikan Sains

The objective of this study is to elucidate the errors made by tenth-grade students at SMA Hati Bilingual Boarding School Probolinggo, Indonesia, when tackling Higher Order Thinking Skills (HOTS) questions on exponential equations, along with the scaffolding process employed to mitigate these errors. Employing qualitative research methods, four participants were chosen based on their performance in completing HOTS questions on exponential equations, followed by in-depth interviews. The identified student errors encompass basic errors, appropriate errors, missing information, and partial insights. The analysis aligns these errors predominantly with Brodie’s error taxonomy. Furthermore, the study highlights the efficacy of instructional scaffolding, utilizing …

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Analysis Of Student Engagement And Perceptions Of Community Of Inquiry (Coi)-Based Blended Learning In The Chemical Separation Subject On Chromatography, Agita Dzulhajh Anggraini, Surjani Wonorahardjo, Yudhi Utomo Sep 2023

Analysis Of Student Engagement And Perceptions Of Community Of Inquiry (Coi)-Based Blended Learning In The Chemical Separation Subject On Chromatography, Agita Dzulhajh Anggraini, Surjani Wonorahardjo, Yudhi Utomo

Jurnal Pendidikan Sains

Learning in higher education has often been conducted solely through face-to-face, teacher- centered approaches. Implementing Community of Inquiry (CoI)-based blended learning in chromatography is crucial as it offers students a novel learning experience. This pre- experimental study, utilizing a one-group pretest-posttest design, aimed to describe students’ perceptions of CoI-based blended learning in chromatography. Data were collected using a questionnaire comprising 34 statements. The results indicated that students had a neutral perception of CoI-based blended learning. While a community of inquiry has been established, it has not yet reached its full potential, as students have not fully experienced social presence in …

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The Identification Of Students’ Conceptual Mastery Of Fluid Statics: An Overview Of Gender, Maria Claudia Sodakain, Sentot Kusairi, Nandang Mufti, Jane Koswojo Sep 2023

The Identification Of Students’ Conceptual Mastery Of Fluid Statics: An Overview Of Gender, Maria Claudia Sodakain, Sentot Kusairi, Nandang Mufti, Jane Koswojo

Jurnal Pendidikan Sains

This study aimed to assess the conceptual mastery of fluid statics among students, employing a descriptive quantitative approach. The research involved 22 male and 13 female students from eleventh-grade MIPA at a private school in Surabaya, Indonesia. The primary research instrument comprised 11 multiple-choice and reasoning questions, covering concepts related to Pressure and Hydrostatic Pressure, Pascal’s Law, and Archimedes’ Principle. Results indicated a higher level of conceptual mastery among male students compared to their female counterparts. While both genders demonstrated relatively high conceptual mastery in Pressure and Hydrostatic Pressure, significant disparities were observed in their understanding of Pascal’s Law and …

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Neural Mechanisms For The Localization Of Unexpected External Motion, Suma Chinta, Scott R. Pluta Sep 2023

Neural Mechanisms For The Localization Of Unexpected External Motion, Suma Chinta, Scott R. Pluta

Purdue University Libraries Open Access Publishing Fund

To localize objects during active sensing, animals must differentiate stimuli caused by volitional movement from real-world object motion. To determine a neural basis for this ability, we examined the mouse superior colliculus (SC), which contains multiple egocentric maps of sensorimotor space. By placing mice in a whisker-guided virtual reality, we discovered a rapidly adapting tactile response that transiently emerged during externally generated gains in whisker contact. Responses to self-generated touch that matched self-generated history were significantly attenuated, revealing that transient response magnitude is controlled by sensorimotor predictions. The magnitude of the transient response gradually decreased with repetitions in external motion, …

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The Role Of Non-Coding Rnas In Myelodysplastic Neoplasms, Vasileios Georgoulis, Epameinondas Koumpis, Eleftheria Hatzimichael Sep 2023

The Role Of Non-Coding Rnas In Myelodysplastic Neoplasms, Vasileios Georgoulis, Epameinondas Koumpis, Eleftheria Hatzimichael

Computational Medicine Center Faculty Papers

Myelodysplastic syndromes or neoplasms (MDS) are a heterogeneous group of myeloid clonal disorders characterized by peripheral blood cytopenias, blood and marrow cell dysplasia, and increased risk of evolution to acute myeloid leukemia (AML). Non-coding RNAs, especially microRNAs and long non-coding RNAs, serve as regulators of normal and malignant hematopoiesis and have been implicated in carcinogenesis. This review presents a comprehensive summary of the biology and role of non-coding RNAs, including the less studied circRNA, siRNA, piRNA, and snoRNA as potential prognostic and/or predictive biomarkers or therapeutic targets in MDS.

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Purification And Characterization Of Mitochondrial Mg2+-Independent Sphingomyelinase From Rat Brain, Jong Min Choi, Yongwei Piao, Kyong Hoon Ahn, Seok Kyun Kim, Jong Hoon Won, Jae Hong Lee, Ji Min Jang, In Chul Shin, Zhicheng Fu, Sung Yun Jung, Eui Man Jeong, Dae Kyong Kim Sep 2023

Purification And Characterization Of Mitochondrial Mg2+-Independent Sphingomyelinase From Rat Brain, Jong Min Choi, Yongwei Piao, Kyong Hoon Ahn, Seok Kyun Kim, Jong Hoon Won, Jae Hong Lee, Ji Min Jang, In Chul Shin, Zhicheng Fu, Sung Yun Jung, Eui Man Jeong, Dae Kyong Kim

Faculty, Staff and Students Publications

Sphingomyelinase (SMase) catalyzes ceramide production from sphingomyelin. Ceramides are critical in cellular responses such as apoptosis. They enhance mitochondrial outer membrane permeabilization (MOMP) through self-assembly in the mitochondrial outer membrane to form channels that release cytochrome c from intermembrane space (IMS) into the cytosol, triggering caspase-9 activation. However, the SMase involved in MOMP is yet to be identified. Here, we identified a mitochondrial Mg

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Existing Evidence For Influenza B Virus Adaptations To Drive Replication In Humans As The Primary Host, Matthew J. Pekarek, Eric A. Weaver Sep 2023

Existing Evidence For Influenza B Virus Adaptations To Drive Replication In Humans As The Primary Host, Matthew J. Pekarek, Eric A. Weaver

Nebraska Center for Virology: Faculty Publications

Influenza B virus (IBV) is one of the two major types of influenza viruses that circulate each year. Unlike influenza A viruses, IBV does not harbor pandemic potential due to its lack of historical circulation in non-human hosts. Many studies and reviews have highlighted important factors for host determination of influenza A viruses. However, much less is known about the factors driving IBV replication in humans. We hypothesize that similar factors influence the host restriction of IBV. Here, we compile and review the current understanding of host factors crucial for the various stages of the IBV viral replication cycle. While …

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Did Cover Crop Or Animal Manure Ameliorate Corn Residue Removal Effects On Soil Mechanical Properties After 10 Years?, Hans W. Klopp, Humberto Blanco-Canqui, Michael Sindelar, Virginia L. Jin, Marty R. Schmer, Richard B. Ferguson Sep 2023

Did Cover Crop Or Animal Manure Ameliorate Corn Residue Removal Effects On Soil Mechanical Properties After 10 Years?, Hans W. Klopp, Humberto Blanco-Canqui, Michael Sindelar, Virginia L. Jin, Marty R. Schmer, Richard B. Ferguson

Department of Agronomy and Horticulture: Faculty Publications

Crop residue removal may negatively affect soil mechanical properties, which are key components of soil quality. To evaluate potential long-term effects, we assessed the 10-yr impact of corn (Zea mays L.) residue removal (59 % of non-grain biomass annually) on surface soil mechanical properties (0–20 cm). We also evaluated whether adding carbon (C) amendments, such as using a winter rye (Secale cereale L.) cover crop or surface-applying cattle manure (24 Mg ha− 1 biannually) can ameliorate the effects of crop residue removal. This long-term study was under irrigated no-till continuous corn on a silt loam soil in south-central …

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Water Quality Of Madari Khal Tributary Of The Halda River, Chattogram, Bangladesh, Md. Shafiqul Islam, M.A. Azadi Sep 2023

Water Quality Of Madari Khal Tributary Of The Halda River, Chattogram, Bangladesh, Md. Shafiqul Islam, M.A. Azadi

Journal of Bioresource Management

Tidal canal Madari-Khal is one of the important tributaries of the river Halda, through which nearby hill stream water, agricultural washings, and effluents (treated or untreated) of Chattogram Asian paper Mill are drained to the Halda River. In this paper water quality and pollution level of Madari Khal are presented. A one-year study was conducted to ascertain the water quality and pollution level by using different physicochemical parameters i.e. Air temperature, Water temperature, Transparency, EC (Electrical Conductivity), TDS (Total Dissolved Solids), pH, DO (Dissolved Oxygen), freeCO2, Ca++ (Calcium), TH (Total Hardness), TA (Total Alkalinity), and Biological Oxygen …

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Deleterious Heteroplasmic Mitochondrial Mutations Are Associated With An Increased Risk Of Overall And Cancer-Specific Mortality, Yun Soo Hong, Stephanie L Battle, Wen Shi, Daniela Puiu, Vamsee Pillalamarri, Jiaqi Xie, Nathan Pankratz, Nicole J Lake, Monkol Lek, Jerome I Rotter, Stephen S Rich, Charles Kooperberg, Alex P Reiner, Paul L Auer, Nancy Heard-Costa, Chunyu Liu, Meng Lai, Joanne M Murabito, Daniel Levy, Megan L Grove, Alvaro Alonso, Richard Gibbs, Shannon Dugan-Perez, Lukasz P Gondek, Eliseo Guallar, Dan E Arking Sep 2023

Deleterious Heteroplasmic Mitochondrial Mutations Are Associated With An Increased Risk Of Overall And Cancer-Specific Mortality, Yun Soo Hong, Stephanie L Battle, Wen Shi, Daniela Puiu, Vamsee Pillalamarri, Jiaqi Xie, Nathan Pankratz, Nicole J Lake, Monkol Lek, Jerome I Rotter, Stephen S Rich, Charles Kooperberg, Alex P Reiner, Paul L Auer, Nancy Heard-Costa, Chunyu Liu, Meng Lai, Joanne M Murabito, Daniel Levy, Megan L Grove, Alvaro Alonso, Richard Gibbs, Shannon Dugan-Perez, Lukasz P Gondek, Eliseo Guallar, Dan E Arking

Faculty, Staff and Student Publications

Mitochondria carry their own circular genome and disruption of the mitochondrial genome is associated with various aging-related diseases. Unlike the nuclear genome, mitochondrial DNA (mtDNA) can be present at 1000 s to 10,000 s copies in somatic cells and variants may exist in a state of heteroplasmy, where only a fraction of the DNA molecules harbors a particular variant. We quantify mtDNA heteroplasmy in 194,871 participants in the UK Biobank and find that heteroplasmy is associated with a 1.5-fold increased risk of all-cause mortality. Additionally, we functionally characterize mtDNA single nucleotide variants (SNVs) using a constraint-based score, mitochondrial local constraint …

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Effects Of Game-Based Learning On Student Engagement And Academic Achievement Of Metabolism Of Biomolecules In The First Year Nursing Students, Aranya Boontham, Rossukon Charoensatsiri Sep 2023

Effects Of Game-Based Learning On Student Engagement And Academic Achievement Of Metabolism Of Biomolecules In The First Year Nursing Students, Aranya Boontham, Rossukon Charoensatsiri

Journal of Education Studies

Although the study of the metabolism of biomolecules is difficult, complicated and many students failed the exam, it is fundamental knowledge for first-year nursing students to understand and apply professionally in the future. This research used game-based learning to increase student engagement and learning outcomes for 150 first-year nursing students in Phrapokklao Nursing College, Chanthaburi. Several platforms and games were used to teach four chapters, including carbohydrate, lipid, protein and nucleic metabolism, with each chapter receiving 2 hours of classroom instruction in addition to self-study review. The research instruments consisted of measures of student engagement, pre-test and post-test assessments of …

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Ochrobactrum, Bacillus And Enterobacter Isolates Of Hot Water Spring Augment The Growth Of Zea Mays Seedlings, Noor-E-Saba Naz, Rida Batool, Nazia Jamil Sep 2023

Ochrobactrum, Bacillus And Enterobacter Isolates Of Hot Water Spring Augment The Growth Of Zea Mays Seedlings, Noor-E-Saba Naz, Rida Batool, Nazia Jamil

Journal of Bioresource Management

Hot springs situated at high altitudes is a kind of remarkable ecosystem for the exploration of microbial flora. It was hypothesized that hot springs can harbor bacteria with plant growth-promoting and exopolysaccharides (EPS) producing ability that can favour the growth of plants. For the investigation of this hypothesis, seven EPS producing bacterial isolates were isolated from a water sample of hot water spring of Tattapani, Azad Kashmir and characterized morphologically and biochemically. Three out of seven isolates (BE1, BN1 and BN3) showed significant production of EPS (14-15 mg / 100 ml). Growth kinetics study revealed that optimum EPS production was …

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A Ck2 And Sumo-Dependent, Pml Nb-Involved Regulatory Mechanism Controlling Blm Ubiquitination And G-Quadruplex Resolution, Shichang Liu, Erin Atkinson, Adriana Paulucci-Holthauzen, Bin Wang Sep 2023

A Ck2 And Sumo-Dependent, Pml Nb-Involved Regulatory Mechanism Controlling Blm Ubiquitination And G-Quadruplex Resolution, Shichang Liu, Erin Atkinson, Adriana Paulucci-Holthauzen, Bin Wang

Faculty, Staff and Student Publications

The Boom syndrome helicase (BLM) unwinds a variety of DNA structures such as Guanine (G)-quadruplex. Here we reveal a role of RNF111/Arkadia and its paralog ARKL1, as well as Promyelocytic Leukemia Nuclear Bodies (PML NBs), in the regulation of ubiquitination and control of BLM protein levels. RNF111 exhibits a non-canonical SUMO targeted E3 ligase (STUBL) activity targeting BLM ubiquitination in PML NBs. ARKL1 promotes RNF111 localization to PML NBs through SUMO-interacting motif (SIM) interaction with SUMOylated RNF111, which is regulated by casein kinase 2 (CK2) phosphorylation of ARKL1 at a serine residue near the ARKL1 SIM domain. Upregulated BLM in …

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Updates On The Immune Cell Basis Of Hepatic Ischemia-Reperfusion Injury, Mi Jeong Heo, Ji Ho Suh, Kyle L Poulsen, Cynthia Ju, Kang Ho Kim Sep 2023

Updates On The Immune Cell Basis Of Hepatic Ischemia-Reperfusion Injury, Mi Jeong Heo, Ji Ho Suh, Kyle L Poulsen, Cynthia Ju, Kang Ho Kim

Faculty, Staff and Student Publications

Liver ischemia-reperfusion injury (IRI) is the main cause of organ dysfunction and failure after liver surgeries including organ transplantation. The mechanism of liver IRI is complex and numerous signals are involved but cellular metabolic disturbances, oxidative stress, and inflammation are considered the major contributors to liver IRI. In addition, the activation of inflammatory signals exacerbates liver IRI by recruiting macrophages, dendritic cells, and neutrophils, and activating NK cells, NKT cells, and cytotoxic T cells. Technological advances enable us to understand the role of specific immune cells during liver IRI. Accordingly, therapeutic strategies to prevent or treat liver IRI have been …

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Impact Of Perceived Environmental Restorativeness On Tourists’ Pro-Environmental Behavior: Examining The Mediation Of Place Attachment And The Moderation Of Ecocentrism, Bin Zhou, Luting Wang, Songshan Huang, Qihao Xiong Sep 2023

Impact Of Perceived Environmental Restorativeness On Tourists’ Pro-Environmental Behavior: Examining The Mediation Of Place Attachment And The Moderation Of Ecocentrism, Bin Zhou, Luting Wang, Songshan Huang, Qihao Xiong

Research outputs 2022 to 2026

Guided by attention restoration theory and stimulus-organism-response (S-O-R) theory, we developed an integrated model to investigate the impact of perceived environmental restoration on forest park visitors' pro-environmental behavior through the mediation of place attachment. We further tested the moderating role of eco-centrism to provide theoretical and practical implications for the sustainability of tourism destinations and positive human-nature interactions. Using a sample of 504 visitors to a national forest park in China, our study indicated all three dimensions of environmental restorative perception (compatibility, extent, and away) positively influenced place attachment. Place attachment promoted pro-environmental behavior. Place attachment was an important mediator …

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The Effect Of Risk Message Framing On Tourist Safety Behavior: A Heuristic-Systematic Model Perspective, Chaowu Xie, Lingling Fan, Jiangchi Zhang, Songshan Huang Sep 2023

The Effect Of Risk Message Framing On Tourist Safety Behavior: A Heuristic-Systematic Model Perspective, Chaowu Xie, Lingling Fan, Jiangchi Zhang, Songshan Huang

Research outputs 2022 to 2026

This research examined the effect of pandemic risk message framing (amplifying vs. attenuating) on tourists' safety behavior from the perspective of heuristic-systematic information processing, as well as the roles of ontological security threat and public opinion climate of risk in moderating such effect. The results of two experiments showed that risk message framing had significant effects on tourists' heuristic processing and systematic processing, and systematic processing mediated the effect of risk message framing on tourists' safety behavior. Furthermore, ontological security threat and public opinion climate of risk strengthened tourists' heuristic processing of risk message; they also moderated the mediation effect …

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Effects Of Bacillus Thuringiensis, Beauveria Bassiana, Neem, And A Tomato Inter-Crop On Diamondback Moth (Plutella Xylostella L.) (Lepidoptera: Plutellidae) In Tharaka-Nithi County, Kenya, Ceciliah N. Ngugi, Jesca N. Mbaka Mbaka, Hellen W. Muthengi Sep 2023

Effects Of Bacillus Thuringiensis, Beauveria Bassiana, Neem, And A Tomato Inter-Crop On Diamondback Moth (Plutella Xylostella L.) (Lepidoptera: Plutellidae) In Tharaka-Nithi County, Kenya, Ceciliah N. Ngugi, Jesca N. Mbaka Mbaka, Hellen W. Muthengi

Tanzania Journal of Science

Cabbage (Brassica oleracea var. capitata) is an important crop in Kenya, ranked 3rd among the exotic vegetables. Diamondback moth (DBM) is a major cabbage pest that can cause a 100% loss in yield if not well managed. Farmers indiscriminately use synthetic pesticides associated with environmental, health, and pest resistance concerns to manage the DBM. To increase the availability of technologies for effective management of DBM in Kenya, three biopesticides; BioPower (Beauveria bassiana 1.0 x 108 CFUs/g), Dipel DF® (Bacillus thuringiensis subsp. kurstaki), Neemraj Super 3000 (Azadirachtin 0.3% EC), and a tomato inter-crop were evaluated. Cabbages (30 plants) spaced at 40 …

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