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Medicine and Health Sciences

2017

Turkish Journal of Medical Sciences

Local risks

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Oral Lichen Planus: A 4-Year Clinical Follow-Up Study, Arunas Rimkevicius, Jolanta Aleksejuniene, Alina Puriene, Dmitrij Seinin, Ruta Rasteniene Jan 2017

Oral Lichen Planus: A 4-Year Clinical Follow-Up Study, Arunas Rimkevicius, Jolanta Aleksejuniene, Alina Puriene, Dmitrij Seinin, Ruta Rasteniene

Turkish Journal of Medical Sciences

Background/aim: This study aimed to examine oral lichen planus (OLP) cases histopathologically and cytologically, describe different clinical aspects of OLP manifestations, and associate different OLP clinical forms with self-reported oral health and with local and systemic risk factors. Materials and methods: All patients with a referral diagnosis of OLP received biopsies. The histological evaluation assessed infiltration with lymphocytes, epithelial hyperplasia, and hyperkeratosis. Histology was used to validate the OLP diagnosis and to evaluate the malignant transformation of OLP lesions. Clinical manifestations of OLP and potential local oral environment-related risks were clinically assessed. Systemic risks were evaluated by a structured questionnaire. …