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An In Vitro Study Of The Role Of Implant Positioning On Ulnohumeral Articular Contact In Distal Humeral Hemiarthroplasty, Roxanna E. Abhari, Ryan Willing, Graham J.W. King, James A. Johnson
An In Vitro Study Of The Role Of Implant Positioning On Ulnohumeral Articular Contact In Distal Humeral Hemiarthroplasty, Roxanna E. Abhari, Ryan Willing, Graham J.W. King, James A. Johnson
Bone and Joint Institute
© 2017 American Society for Surgery of the Hand Purpose To investigate the effect of implant positioning on ulnohumeral contact using patient-specific distal humeral (DH) implants. Methods Seven reverse-engineered DH implants were manufactured based on computed tomography scans of their osseous geometry. Native ulnae were paired with corresponding native humeri and custom DH implants in a loading apparatus. The ulna was set at 90° of flexion and the humeral component (either native bone or reverse-engineered implant) was positioned from 5° varus to 5° valgus in 2.5° increments under a 100-N compressive load. Contact with the ulna was measured with both …
Delayed Endothelial Progenitor Cell Therapy Promotes Bone Defect Repair In A Clinically Relevant Rat Model, Brent D. Bates, Charles Godbout, David J. Ramnaraign, Emil H. Schemitsch, Aaron Nauth
Delayed Endothelial Progenitor Cell Therapy Promotes Bone Defect Repair In A Clinically Relevant Rat Model, Brent D. Bates, Charles Godbout, David J. Ramnaraign, Emil H. Schemitsch, Aaron Nauth
Bone and Joint Institute
© 2017 Brent D. Bates et al. The repair of segmental bone defects remains a significant challenge for orthopaedic surgeons. Endothelial progenitor cells (EPCs) have successfully promoted the repair of acute defects in animal models; however, the ability of EPCs to induce the repair of chronic nonhealing defects, such as those often encountered clinically, has not been investigated. Therefore, the purpose of this study was to investigate the ability of EPCs delivered in delayed fashion to induce the repair of nonhealing defects in a clinically relevant model. In order to simulate delayed treatment, 5 mm segmental defects in Fischer 344 …