Digital Commons Network^™

Material Potential | Recontextualizing Material Libraries, Diana Wagner

Masters Theses

Material libraries are growing resources that offer an opportunity for artists and designers to discover a variety of materials. These collections are composed in a traditional taxonomy, pairing materials based on composition. Samples are typically commercially made and are displayed independent of context, means of production, cultural significance, and application.

Through making we learn a material’s potential: the transformation it can make, the form it can take, and the new composites we can create. This generative experience lives in the studio and workshop. But how can we introduce this language of process, critical thinking, and making to activate and challenge …

Shellfish Closure Trends Near Mt. Desert Island, Maine, Marianne Ferguson

CLAS: Colby Liberal Arts Symposium

Shellfish are a popular commercial fishery harvest in Maine. However, they are susceptible to biotoxins transmitted by toxic phytoplankton, which can lead to paralytic or amnesic shellfish poisoning of the humans that consume them. The Maine Department of Marine Resources has a phytoplankton monitoring program in place to detect such biotoxins and to close areas of shellfish harvesting if need be. Since 2001, they have archived the data from every closure. One of Maines shellfish species, the Blue Mussel, is sensitive to environmental changes and is known as a bio-monitor of pollution. Therefore, a method will be developed to analyze …

Mainecare Stage A Health Homes Year 1 Report: Implementation Findings And Baseline Analysis, Kimberley S. Fox Mpa, Carolyn E. Gray Mph, Katherine Rosingana, Deborah A. Thayer Mba

Population Health & Health Policy

In January 2013, Maine established Health Homes under federal authority pursuant to Section 2703 of the Affordable Care Act to improve care coordination for MaineCare members with chronic conditions. Stage A of the Health Homes initiative focuses on members with complex medical chronic conditions. Stage B, planned for early 2014, will focus on persons with severe and persistent mental health conditions and children with serious emotional disturbances. The Stage A demonstration builds off the State’s existing Maine multi-payer Patient Centered Medical Home (PCMH) Pilot project and Maine’s Medicare Advanced Primary Care Practice (MAPCP) Demonstration by providing add-on payments to primary …

Hassett Coauthors Paper Assessing Global Warming Impact On Tiny Atlantic Crustaceans, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Mechanistic Target Of Rapamycin (Mtor) Signaling Genes In Decapod Crustaceans: Cloning And Tissue Expression Of Mtor, Akt, Rheb, And S6 Kinase In The Green Crab, Carcinus Maenas, And Blackback Land Crab, Gecarcinus Lateralis, Ali M. Abuhagr, Kyle S. Maclea, Ernest S. Chang, Donald L. Mykles

Life Sciences Faculty Scholarship

Mechanistic target of rapamycin (mTOR) controls global translation of mRNA into protein by phosphorylating p70 S6 kinase (S6K) and eIF4E-binding protein-1. Akt and Rheb, a GTP-binding protein, regulate mTOR protein kinase activity. Molting in crustaceans is regulated by ecdysteroids synthesized by a pair of molting glands, or Y-organs (YOs), located in the cephalothorax. During premolt, the YOs hypertrophy and increase production of ecdysteroids. Rapamycin (1 μM) inhibited ecdysteroid secretion in Carcinus maenas and Gecarcinus lateralis YOs in vitro, indicating that ecdysteroidogenesis requires mTOR-dependent protein synthesis. The effects of molting on the expression of four key mTOR signaling genes (mTOR, Akt, …

A Unique Covalent Bond In Basement Membrane Is A Primordial Innovation For Tissue Evolution, Aaron L. Fidler, Roberto M. Vanacore, Sergei V. Chetyrkin, Vadim K. Pedchenko, Gautam Bhave, Viravuth P. Yin, Cody L. Stothers, Kristie Lindsey Rose, W. Hayes Mcdonald, Travis A. Clark, Dorin-Bogdan Borza, Robert E. Steele, Michael T. Ivy, The Aspirnauts, Julie K. Hudson, Billy G. Hudson

Biology Faculty Research

We recently discovered that the collagen IV scaffolds of bovine, mouse, and Drosophila melanogaster tissues are stabilized by sulfilimine chemical bonds (S = N) (20⇓–22). The bond is a covalent cross-link between methionine-93 (Met93) and lysine-211 or hydroxylysine-211 (Lys211/Hyl211) residues that stabilizes the noncollagenous (NC1) interface of adjoining triple helical protomers (Fig. 1A). Peroxidasin, an animal heme peroxidase embedded in basement membrane, forms these sulfilimine cross-links by producing hypohalous acids as intermediates for Met93 oxidization (21, 22). Here, we explored whether the sulfilimine cross-link of collagen IV is a fundamental requirement in the genesis and evolution of tissues in Eumetazoa. …

Facilitating Lewin's Change Model With Collaborative Evaluation In Promoting Evidence Based Practices Of Health Professionals, Julianne Manchester, Deanna L. Gray-Miceli, Judith A. Metcalf, Charlotte A. Paolini, Anne H. Napier, Constance L. Coogle, Myra G. Owens

Virginia Center on Aging Publications

Evidence based practices (EBPs) in clinical settings interact with and adapt to host organizational characteristics. The contextual factors themselves, surrounding health professions’ practices, also adapt as practices become sustained. The authors assert the need for better planning models toward these contextual factors, the influence of which undergird a well-documented science to practice gap in literature on EBPs. The mechanism for EBP planners to anticipate contextual effects as programs Unfreeze their host settings, create Movement, and become Refrozen (Lewin, 1951) is present in Lewin's 3-step change model. Planning for contextual change appears equally important as planning for the actual practice outcomes …

Mutations In The Gene That Encodes The F-Actin Binding Protein Anillin Cause Fsgs, R. A. Gbadegesin, G. Hall, A. Adeyemo, N. Hanke, I. Tossidou, J. Burchette, G. H. Wu, A. Homstad, P. C. Singhal, M. P. Winn, +17 Additional Authors

Journal Articles

FSGS is characterized by segmental scarring of the glomerulus and is a leading cause of kidney failure. Identification of genes causing FSGS has improved our understanding of disease mechanisms and points to defects in the glomerular epithelial cell, the podocyte, as a major factor in disease pathogenesis. Using a combination of genome-wide linkage studies and whole-exonne sequencing in a kindred with familial FSGS, we identified a missense mutation R431C in anillin (ANLN), an F-actin binding cell cycle gene, as a cause of FSGS. We screened 250 additional families with FSGS and found another variant, G618C, that segregates with disease in …

Early Lessons Learned In Implementing Mainecare Health Homes, Kimberley S. Fox Mpa, Carolyn E. Gray Mph, Katherine Rosingana

Population Health & Health Policy

The MaineCare Health Homes Initiative is designed to improve care coordination for MaineCare members with complex chronic medical conditions. The initiative, which began in January 2013, builds off the State’s existing multi-payer Patient Centered Medical Home (PCMH) Pilot project and Medicare Advanced Primary Care Practice (MAPCP) Demonstration by providing add-on payments to primary care practices to provide “whole person” integrated care coordination for MaineCare members with specific chronic conditions. For the highest need patients, practices work with Community Care Teams (CCT) that provide short-term care management and social support services. The Muskie School of Public Service is evaluating the implementation …

Colby College Catalogue 2014 - 2015, Colby College

Colby Catalogues

Colby College Catalogue: September 2014 - August 2015

Natural Selection Canalizes Expression Variation Of Environmentally Induced Plasticity-Enabling Genes, Joseph R. Shaw, Thomas H. Hampton, Benjamin L. King, Andrew Whitehead, Fernando Galvez, Robert H. Gross, Nathan Keith, Emily Notch, Dawoon Jung, Stephen P. Glaholt, Celia Y. Chen, John K. Colbourne, Bruce A. Stanton

Faculty Publications

© 2014 The Author. Many organisms survive fluctuating and extreme environmental conditions by manifesting multiple distinct phenotypes during adulthood by means of developmental processes that enable phenotypic plasticity. We report on the discovery of putative plasticity-enabling genes that are involved in transforming the gill of the euryhaline teleost fish, Fundulus heteroclitus, from its freshwater to its seawater gill-type, a process that alters both morphology and function. Gene expression that normally enables osmotic plasticity is inhibited by arsenic. Gene sets defined by antagonistic interactions between arsenic and salinity show reduced transcriptional variation among individual fish, suggesting unusually accurate and precise regulatory …

Lichens Of Six Vernal Pools In Acadia National Park, Me, Usa, J. Barton, B. Ciccotelli, J. E. Gall, F. C. Olday, B. Connery, T. B. Harris, A. M. Fryday, Nishanta Rajakaruna

Faculty Publications, Biological Sciences

Whereas lichen-habitat relations have been well-documented globally, literature on lichens of vernal pools is scant. We surveyed six vernal pools at Acadia National Park on Mount Desert Island, Maine, USA for their lichen diversity. Sixty-seven species were identified, including seven species that are new reports for Acadia National Park: Fuscidea arboricola, Hypogymnia incurvoides, Lepraria finkii, Phaeographis inusta, Ropalospora viridis, Usnea flammea, and Violella fucata. Five species are considered uncommon or only locally common in New England: Everniastrum catawbiense, Hypogymnia krogiae, Pseudevernia cladonia, Usnea flammea, and Usnea merrillii. This work represents the first survey of lichens from vernal pools in Acadia …

Cellular Coping Mechanisms To Hypoxia In The Longhorn Sculpin (Myoxocephalus Octodecemspinosus) Brain, Kelly Heino

College of Graduate Studies: Theses & Dissertations

The loss of neurological function due to hypoxia remains to be a challenge in many species due to the lack of knowledge and understanding of cellular responses. To investigate cellular responses and survival strategies of the brain during hypoxia and post-hypoxia recovery in a moderate hypoxia-tolerant species, with the hopes of identifying possible therapeutic remedies, thirty Longhorn sculpin, Myoxocephalus octodecimspinosus, were challenged with acute hypoxia (40% O2 saturation for 1 h) and twelve additional sculpin were used as controls (~90% O₂ saturation). Fish were sampled at each of the following time points: control/normoxic conditions (T=0 h); hypoxic conditions …

The Search, The Jackson Laboratory

Search Magazine

No abstract provided.

Ndls Update 07/16/2013, Notre Dame Law School

NDLS Update

No abstract provided.

The Search, The Jackson Laboratory

Search Magazine

No abstract provided.

Ndls Update 06/04/2013, Notre Dame Law School

NDLS Update

No abstract provided.

The Search, The Jackson Laboratory

Search Magazine

No abstract provided.

The Last Page: Reaching Sierra Leone, Erin Rhoda

Colby Magazine

Erin Rhoda ’06 on touching—and saving—lives in Sierra Leone.

Full Issue

Colby Magazine

Colby Magazine vol. 94, no. 1 (Spring 2005): full issue

Colby News

Colby Magazine

Mixing Religion and Politics

Corporate Social Responsibility?

Stringed Exhibit

Wit & Wisdom

Defending Diversity

Cracking the Code

Aren't We Balmy

Wining and Dining in Dana

Do It Yourself Cookbook

Colby Update: Victor Cancel '02

A Moving Response to Tsunami Disaster

Environmental Excellence

All-American Takes On the World

Die Fledermaus Program [2013], University Of Southern Maine Department Of Theatre

Programs 2012-2013 Season

Operetta by Johann Strauss

Directed by Assunta Kent

Musical Direction by Ellen Chickering

his production was a Participating entry in the Kennedy Center American College Theater Festival (KC/ACTF).

Alumni @ Large

Colby Magazine

Reunion 2008

Alumni notes

Newsmakers

Milestones

Business Model: Charles Morrissey '56

Clarity Is All: Meg Matheson '79

Mission Statement: Eben Dorros '96

Curtain Call: Liz Frankel '01

Obituaries

Full Issue

Colby Magazine

Colby Magazine vol. 98, no. 2 (Summer 2009): full issue

The Boatbuilders: Steve White '77 And Jock Williams '62 Have Built International Reputations Fore Their Classically Inspired Yachts, Matthew P. Murphy

Colby Magazine

In the world of custom-built yachts, Maine boatbuilders Jock Williams ’62 and Steve White ’77 are renowned for their boats’ classic lines and impeccable craftsmanship.

Merepoint Boat Launch Facility Eelgrass Mitigation Measures: 2013 Monitoring Report, Mer Assessment Corporation

Publications

No abstract provided.

Merepoint Boat Launch Facility Eelgrass Mitigation Measures: Final Project Assessment, Mer Assessment Corporation

Publications

No abstract provided.

New England Journal Of Entrepreneurship, Spring/Fall 2013

New England Journal of Entrepreneurship

No abstract provided.

Sustainability: A Paradigmatic Shift In Entrepreneurship Education, Frances M. Amatucci, Nelson Pizarro, Jay Friedlander

New England Journal of Entrepreneurship

This article proposes that sustainability represents a paradigmatic shift from traditional perspectives in entrepreneurship education. This “call to action” argues that it is imperative for entrepreneurship scholars and practitioners to add sustainability to academic curricula and consulting support activities. The evolutionary development of entrepreneurship from the traditional profit-oriented perspective to sustainable entrepreneurship is described. A case study of an academic institution, which has successfully incorporated sustainability principles into its curriculum, is provided.This article is among the first that details the importance of a paradigmatic shift because “business as usual” is no longer effective in the twenty-first century.

An Algorithmic And Information-Theoretic Approach To Multimetric Index Construction, Donald R. Schoolmaster Jr., James B. Grace, E. William Schweiger, Glenn R. Guntenspergen, Brian R. Mitchell, Kathryn M. Miller, Amanda M. Little

United States Geological Survey: Staff Publications

The use of multimetric indices (MMIs), such as the widely used index of biological integrity (IBI), to measure, track, summarize and infer the overall impact of human disturbance on biological communities has been steadily growing in recent years. Initially, MMIs were developed for aquatic communities using preselected biological metrics as indicators of system integrity. As interest in these bioassessment tools has grown, so have the types of biological systems to which they are applied. For many ecosystem types the appropriate biological metrics to use as measures of biological integrity are not known a priori. As a result, a variety of …