Digital Commons Network^™

Jerome Enters. Llc V. Javed

All Decisions

The court granted the tenant's motion to dismiss the landlord's nonpayment case because the building lacked a valid Certificate of Occupancy, which prohibits the collection of rent. The court also held the landlord in civil contempt for failing to comply with a prior so-ordered stipulation to make repairs, which prejudiced the tenant's ability to secure a Section 8 voucher. The landlord's petition was dismissed, but the case was restored to the calendar for a pre-trial conference to address the tenant's counterclaims and determine damages for the contempt finding.

Determining Accurate Pore Structures Of Polypropylene Membrane For Ecmo Using Fe-Sem Under Optimized Conditions, Makoto Fukuda, Yoshiaki Nishite, Eri Murata, Koki Namekawa, Tomohiro Mori, Tsutomu Tanaka, Kiyotaka Sakai

Children’s Nutrition Research Center Staff Publications

Long-term ECMOs are expected to be put into practical use in order to prepare for the next emerging severe infectious diseases after the novel coronavirus pandemic in 2019-2023. While polypropylene (PP) and polymethylpentene (PMP) are currently the mainstream materials for the hollow fiber membranes of ECMO, the PP membrane coated with a silicone layer on the outer surface has also been commercialized. In this study, we sought a method to accurately observe the detailed pore morphologies of the PP membrane by suppressing irreversible changes in the morphology in SEM observation, which is a general-purpose observation with higher resolution. As a …

Beyond Statutory Loopholes, Qualified Immunity, And Internal Investigations: A Comparative Analysis Of Police Accountability In The United States And The United Kingdom, Kevyn Mcconlogue

Brooklyn Journal of International Law

While the landscape of policing in the United States and United Kingdom appear different today, their shared roots of enslavement and racism fostered a culture of impunity for police officers in both countries. With community skepticism and public discontent with law enforcement continuing to rise in the United States, the investigative and procedural roadblocks in the way of holding police officers accountable for misconduct must come to an end. In an effort to facilitate conversations about progressive police reform and eventual abolition, this Note compares the modern American and British police accountability systems and the avenues through which victims of …

Incorporating Propensity Score Weighting And Nonresposne Adjustments Into Complex Survey Data With Survival Outcomes, Xinrui Shi

Theses and Dissertations

Propensity score weighting (PSW) plays a key role in minimizing confounding in observational research, especially when estimating treatment effects for time-to-event outcomes. However, its integration into survey data with complex design – particularly data with multiple stage sampling and censoring – remains underexplored. One significant challenge in such settings is the presence of nonresponse, which can introduce additional bias and complicate the use of standard weight adjustments. Moreover, there has been limited study on how PS weights can be effectively combined with nonresponse weighting adjustments in complex survey data that include survival outcomes. This dissertation aims to extend current methodologies …

A Provably Secure Coercion-Resistant E-Voting Scheme With Confidentiality, Anonymity, Unforgeability, And Cai Verifiability, Yun Xing Kho, Swee Huay Heng, Syh Yuan Tan, Ji Jian Chin

School of Engineering, Computing and Mathematics

Ensuring both cast-as-intended (CAI) verifiability and coercion-resistance in e-voting remains a critical challenge. The e-voting scheme proposed by Finogina and Herranz in 2023 represents the first notable advancement in reconciling these conflicting requirements. CAI verifiability allows voters to confirm that their intended vote has been correctly recorded, even without a secure channel to the election committee, while coercion-resistance prevents external influence and vote-selling. However, essential security properties such as confidentiality, anonymity, unforgeability, and double-voting prevention fall outside the scope of Finogina and Herranz’s e-voting scheme, leaving significant gaps in its security guarantees. To address this limitation, we propose a novel …

Cannabis Concentrate Vaping Chemistry, Kaelas R. Munger, Killian M. Anreise, Robert M. Strongin

Chemistry Faculty Publications and Presentations

Background:

This review article addresses the vaping chemistry of manufactured cannabis concentrates—a topic that remains under-researched despite the widespread availability and growing popularity of these products. Given their current prevalence and the fact that many of the findings discussed herein are from early-stage investigations, further research is essential to fully assess the public health risks associated with concentrate use. The purpose of this article is to help begin to bridge this knowledge gap by outlining the technical challenges of studying cannabis concentrates and to present evidence-based data concerning toxicant exposures as a foundation for future investigations.

Methods:

A search of …

Radiotherapy Promotes Cuproptosis And Synergizes With Cuproptosis Inducers To Overcome Tumor Radioresistance, Guang Lei, Mingchuang Sun, Jun Cheng, Rui Ye, Zhengze Lu, Amber Horbath, David Huo, Shengrong Wu, Anagha Alapati, Sadhna Aggarwal, Zhihao Xu, Chao Mao, Yuelong Yan, Jun Yao, Qidong Li, Xiong Chen, Hyemin Lee, Li Zhuang, Dadi Jiang, Apar Pataer, Jack A Roth, Nicholas Navin, Albert C Koong, Mingjian James You, Steven H Lin, Boyi Gan

Faculty, Staff and Student Publications

Cuproptosis is a recently identified form of copper-dependent cell death. Here, we reveal that radiotherapy (RT) induces cuproptosis in cancer cells, independent of apoptosis and ferroptosis, and depletes lipoylated proteins and iron-sulfur (Fe-S) cluster proteins-both hallmarks of cuproptosis-in patient tumors. Mechanistically, RT elevates mitochondrial copper levels by upregulating copper transporter 1 (CTR1) and depleting mitochondrial glutathione, a copper chelator, thereby triggering cuproptosis. Integrated analyses of RNA sequencing (RNA-seq) from radioresistant esophageal cancer cells and single-cell RNA-seq from esophageal tumors of patients unresponsive to RT link radioresistance to the downregulation of BTB and CNC homology 1 (BACH1). This downregulation de-represses the …

Longitudinal Plasma Amino Acids During Pregnancy And Neonatal Anthropometry: Findings From The Nichd Fetal Growth Studies-Singleton Cohort, Claire Guivarch, Jing Wu, Ruijin Lu, Jagteshwar Grewal, Guoqi Yu, Ling-Jun Li, Jiaxi Yang, Wei Wei Pang, Dong D Wang, Natalie L Weir, Zhen Chen, Michael Y Tsai, Cuilin Zhang

2020-Current year OA Pubs

BACKGROUND: Amino acids (AAs) during pregnancy are crucial for fetal growth. Prior studies measured AA concentrations at single time points in pregnancy, despite their fluctuations throughout pregnancy. We measured plasma AA profiles in blood samples longitudinally collected from early through late pregnancy and evaluated their associations with neonatal anthropometry.

METHODS: Concentrations of plasma aromatic AAs, branched-chain AAs, and AAs involved in one-carbon metabolism were assessed at 10-14, 15-26, 23-31, and 33-39 gestational weeks (GW) among 321 women from a case-control study from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies-Singleton Cohort. Associations …

Lrrc8 Channel Complexes Counterbalance Katp Channels To Mediate Swell-Secretion Coupling In Mouse Pancreatic Β Cells, Tarek Mohamed Abd El-Aziz, Chen Kang, Litao Xie, John D. Tranter, Sumit Patel, Rahul Chadda, Maria S. Remedi, Rajan Sah

2020-Current year OA Pubs

Insulin secretion from pancreatic β cells is initiated by membrane potential depolarization, followed by activation of voltage-gated Ca2+ channels to trigger Ca2+-mediated insulin vesicle fusion with the β cell plasma membrane. Here, we show that β cell swelling associated with glucose metabolism was sensed by LRRC8 channel complexes and contributed to insulin secretion. Hypertonic perfusate (360-380 mOsm) dose dependently impaired glucose-stimulated insulin secretion by counteracting β cell swelling. Hypotonic perfusate alone, independent of glucose stimulation or KATP channel closure, was sufficient to increase β cell intracellular Ca2+ and trigger insulin secretion. Inhibition of sodium-potassium-chloride cotransporter-1 with bumetanide, which diminished the …

Long-Term Nitrogen Fertilization Inhibits Carbon And Nitrogen Loss During Late-Stage Fungal Necromass Decomposition Depending On Necromass Chemistry, Lang C. Delancey, Craig R. See, Katherine Heckman, Peter G. Kennedy, Sarah E. Hobbie

Michigan Tech Publications

Fungal necromass is increasingly recognized as a key component of soil carbon (C) and nitrogen (N) cycling. However, how C and N loss from fungal necromass during decomposition is impacted by global change factors such as anthropogenic N addition and changes to soil C supply (e.g. via changing root exudation and rhizosphere priming) remains unclear and understudied relative to plant tissues. To address these gaps, we conducted a year-long decomposition experiment with four species of fungal necromass incubated across four forested sites in plots that had received inorganic N and/or labile C fertilization for two decades in Minnesota, USA. We …

Specialized Insectivores Drive Differences In Avian Community Composition Between Primary And Secondary Forest In Central Africa, Eleanor M. Barrie, Billi A. Krochuk, Crinan Jarrett, Diogo F. Ferreira, Patricia F. Rodrigues, Susana Lin Mufumu, Silvestre Esteban Malanza, Agustin Ebana Nsue Akele, Cayetano Ebana Ebana Alene, Kristin Brzeski, Jacob C. Cooper, Jared Wolfe, Luke L. Powell

Michigan Tech Publications

The human population of sub-Saharan Africa is projected to triple by 2100, drastically increasing anthropogenic pressure on biodiversity. When rainforest is disturbed by anthropogenic drivers, species respond heterogeneously; these patterns have rarely been quantified for Congo rainforest fauna. Our objective was to understand how community composition changed with human disturbance—with particular interest in the guilds and species that indicate primary rainforest. At a long-term bird banding site on mainland Equatorial Guinea, we captured over 3200 birds across 6 field seasons in selectively logged secondary forest and in largely undisturbed primary forest. Our multivariate ordination indicated a significant split between primary …

Black Soldier Fly, Hermetia Illucens, Larvae Meal Improves Intestinal Health And Growth Performance Of Nile Tilapia, Oreochromis Niloticus, Juveniles, Sahya Maulu, Ben Eynon, Sherilyn Abarra, Mark Rawling, Daniel Merrifield

School of Biological and Marine Sciences

This study investigated the effects of dietary black soldier fly (BSF) larvae, Hermetia illucens, meal on growth performance, feed utilization, intestinal health, and immune response in Nile tilapia, Oreochromis niloticus, juveniles. The fish (initial weight: 7.28 ± 0.09 g) were reared in a recirculatory aquaculture system (RAS) and fed diets containing different levels of defatted BSF larvae meal: 0% (control diet), 20% (BSF20), and 40% (BSF40). At the end of the feeding trial, the final body weight, weight gain, specific growth rate (SGR), protein efficiency ratio (PER), and feed conversion ratio (FCR) were significantly (p < 0.05) improved with increasing BSF meal inclusion levels in the diet. Histological analysis of the intestine revealed that mucosal fold length (MFL), muscularis thickness (MT), and goblet cell density (GCD) were significantly elevated by the BSF meal compared with the control. In addition, intraepithelial lymphocytes (IELs) and the enterocyte microvilli length were significantly elevated in BSF40-fed fish compared with the control. Gene expression analysis showed that intestinal chitin digestion-related (endochitinase A) and amino acid transporter (Slc6a18) genes were not significantly affected by the BSF meal. However, the expression of peptide transporter Slc15a1a was upregulated in the fish fed BSF40 compared to the control. Moreover, posterior intestine and head kidney cytokine (IL-1β, TNF-α, and IL-10) gene expression levels were not significantly affected by the inclusion of the BSF meal. Therefore, these results suggest that the BSF meal up to a 40% inclusion level can be used as an alternative protein source in the diets of Nile tilapia juveniles to promote growth and intestinal health.

Designing For Dissemination Through Community Advisory Board Engagement In An Implementation Mapping Process: A Case Study, Gabriella M Mcloughlin, Yerusalem Yohannes, Molly Kerstetter, Omar Martinez, Alex Dopp, Jennifer O Fisher, Maura Kepper, Rachel G Tabak, Ross C Brownson

2020-Current year OA Pubs

INTRODUCTION: The purpose of this study was to document the development of a Community Advisory Board (CAB) to enhance equitable dissemination of research findings within an implementation mapping study to enhance equitable impact of Universal School Meals (USM) through the Designing for Dissemination and Sustainability (D4DS) process.

METHODS: The D4DS process comprises 7 key elements to facilitate meaningful dissemination. To accomplish Step 1: Identify Partners, the research team conducted snowball recruitment methods within the local Philadelphia community and with existing connections. To Empathize and Outline the Problem (Step 2) and Understand the Context (Step 3), an interest meeting was held …

Transformative Integration: Navigating Opportunities And Challenges In A Medical School's Evolution Into Integrated Service Units, Chelsea Chang, Everardo Cobos, Michael Sander, Beatriz Tapia, Michael Hocker

School of Medicine Publications

Medical schools must evolve with the changing healthcare landscape and financial pressures. Academic Health Centers have responded to these changes with a novel organizational model known as an integrated service line. Traditional medical school departments often create silos, lack of alignment, and financial burdens. To our knowledge, we were the first medical school to implement an integrated structure combining the tripartite missions of academics, research, and clinical services.

The University of Texas Rio Grande Valley School of Medicine accepted its charter class of 55 medical students in 2016 with a traditional medical school department model. By 2023, it had 154 …

Brain Tau Pet-Based Identification And Characterization Of Subpopulations In Patients With Alzheimer's Disease Using Deep Learning-Derived Saliency Maps, Yanxiao Li, Xiuying Wang, Qi Ge, Manuel B Graeber, Shaozhen Yan, Jian Li, Shuyu Li, Wenjian Gu, Shuo Hu, Tammie L S Benzinger, Jie Lu, Yun Zhou

2020-Current year OA Pubs

BACKGROUND: Alzheimer's disease (AD) is a heterogeneous neurodegenerative disorder in which tau neurofibrillary tangles are a pathological hallmark closely associated with cognitive dysfunction and neurodegeneration. In this study, we used brain tau data to investigate AD heterogeneity by identifying and characterizing the subpopulations among patients. We included 615 cognitively normal and 159 AD brain

RESULTS: Two distinct subpopulations of AD patients were revealed, denoted as S

CONCLUSION: Our results suggest that tau tangles, as shown by SUVR, continue to accumulate even when cognitive function plateaus in AD patients, highlighting the advantages of PET in later disease stages. The differing relationships …

Current Cutting-Edge Omics Techniques On Musculoskeletal Tissues And Diseases, Xiaofei Li, Liang Fang, Sade W Clayton, Dakota R Kamm, Cuicui Wang, Farshid Guilak, Simon Y Tang, Gretchen A Meyer, Jie Shen, Et Al.

2020-Current year OA Pubs

Musculoskeletal disorders, including osteoarthritis, rheumatoid arthritis, osteoporosis, bone fracture, intervertebral disc degeneration, tendinopathy, and myopathy, are prevalent conditions that profoundly impact quality of life and place substantial economic burdens on healthcare systems. Traditional bulk transcriptomics, genomics, proteomics, and metabolomics have played a pivotal role in uncovering disease-associated alterations at the population level. However, these approaches are inherently limited in their ability to resolve cellular heterogeneity or to capture the spatial organization of cells within tissues, thus hindering a comprehensive understanding of the complex cellular and molecular mechanisms underlying these diseases. To address these limitations, advanced single-cell and spatial omics techniques …

A Forward Genetic Screen Identifies Potassium Channel Essentiality In Shh Medulloblastoma Maintenance, Jerry J Fan, Anders W Erickson, Julia Carrillo-Garcia, Xin Wang, Patryk Skowron, Xian Wang, Xin Chen, Guanqiao Shan, Wenkun Dou, Shahrzad Bahrampour, Yi Xiong, Weifan Dong, Namal Abeysundara, Michelle A Francisco, Ronwell J Pusong, Wei Wang, Miranda Li, Elliot Ying, Raúl A Suárez, Hamza Farooq, Borja L Holgado, Xiaochong Wu, Craig Daniels, Adam J Dupuy, Juan Cadiñanos, Allan Bradley, Anindya Bagchi, Branden S Moriarity, David A Largaespada, A Sorana Morrissy, Vijay Ramaswamy, Stephen C Mack, Livia Garzia, Peter B Dirks, Xuejun Li, Siyi Wanggou, Sean Egan, Yu Sun, Michael D Taylor, Xi Huang

Faculty, Staff and Students Publications

Distinguishing tumor maintenance genes from initiation, progression, and passenger genes is critical for developing effective therapies. We employed a functional genomic approach using the Lazy Piggy transposon to identify tumor maintenance genes in vivo, and applied this to SHH medulloblastoma (MB). Combining Lazy Piggy screening in mice and transcriptomic profiling of human MB, we identified the voltage-gated potassium channel KCNB2 as a candidate maintenance driver. KCNB2 governs cell volume of MB-propagating cells, with KCNB2 depletion causing osmotic swelling, decreased plasma membrane tension, and elevated endocytic internalization of EGFR, thereby mitigating proliferation of MB-propagating cells to ultimately impair MB growth. …

Regulation Of Myogenesis By Mechanomir-200c/Foxo3 Axis, Junaith S Mohamed, Aladin M Boriek

Faculty, Staff and Students Publications

Cyclic mechanical stretch has been shown to inhibit myoblast differentiation while promoting proliferation. However, the underlying molecular mechanisms are not well understood. Here, we report that mechanical stretch inhibits the differentiation of mouse primary myoblasts by promoting the cell cycle program and by inhibiting the expression of the myogenic regulator MyoD. Stretch alters the miRNA expression profile as evidenced by miRNA microarray analysis. We identified miR-200c as one of the highly downregulated mechanosensitive miRNAs (mechanomiRs) whose expression level was increased during differentiation. This suggests that mechanomiRs-200c is a myogenic miRNA. Overexpression of mechanomiR-200c revoked the effect of stretch on myoblast …

Xorcompactor: A Zero-Copy, Reversible Memory Defragmentation Technique For Operating Systems, Mostefa Sayeh Mr

Defensive Publications Series

This disclosure introduces XORCompactor, a novel, reversible, zero-copy memory defragmentation technique for operating systems. Unlike traditional memory movers such as memmove() or memcpy(), XORCompactor performs in-place compaction by leveraging a mathematical XOR-based transformation to swap and relocate memory segments without auxiliary buffers or double-copy overhead. This method ensures lossless reversibility, enabling safe rollback, debugging, and deterministic state recovery. The technique improves memory utilization, reduces fragmentation latency, and supports deterministic behavior in embedded and real-time systems.

XORCompactor includes the proposal of a new instruction-level operation, XOR_MOV, and outlines potential hardware integration for high-throughput memory management. The algorithm has …

Dlfp: A Deterministic Instruction Fetch Architecture For Safety-Critical Electronics, Mostefa Sayeh Mr

Defensive Publications Series

DLFP (Dual-Layer Fetch Pathway) is a novel deterministic instruction fetch architecture tailored for safety-critical systems requiring strict execution timing and resilience. It introduces the Instruction Heatmap Engine (IHE), a lightweight classification mechanism that segments instructions into Hot, Warm, and Cold zones based on execution behavior. By combining this classification with layered fetch queues (L0–L3), DLFP enables deterministic scheduling, thermal-aware promotion, and reduced fetch latency variability. This approach strengthens system predictability, mitigates speculative execution vulnerabilities such as Spectre and Meltdown, and enhances safety in real-time environments including SCADA, avionics, medical electronics, and autonomous robotics. DLFP offers a foundational architecture …

Assessing The Efficacy Of Eutectic Mixture Of Local Anesthesia Cream And Vapocoolant Spray In Mitigating The Pain Associated With Ear-Tagging In Pre-Weaned Calves, Yu-Jhe Lo, Thomas Chia-Tang Ho, Jacky Peng-Wen Chan

The Thai Journal of Veterinary Medicine

This study evaluated the efficacy of a eutectic mixture of local anesthetics (EMLA) cream and vapocoolant spray (VS) in preventing pain in calves following ear-tagging. Thirty-four calves were randomly assigned to three groups: no anesthesia control (CON, n=11), EMLA applied 60 minutes prior (EMLA, n=11), and five-second VS application immediately prior (VS, n=12). Pain pressure threshold (PPT) was measured at 18±1 days of age, with the left ear of the CON group serving as the sham group (Sham, n=11), followed by ear-tagging at 21±1 days. Post-tagging assessments included pain-related behaviors, serum cortisol levels, heart rate, and wound scores. The PPT …

The Love With A Thousand Faces: Heroism As Embodied Love In Action, Scott T. Allison

Heroism Science

In this article, I argue that heroism is, at its core, embodied love in action -- a morally charged, physically grounded expression of care enacted through selfless deeds, courage, and commitment to others. Rather than reducing love to sentiment or an abstract ideal, I emphasize its embodied dimensions: love as a lived, relational force that motivates people to act bravely and altruistically, often at great personal cost. Drawing on psychological research in empathy, attachment, and prosocial motivation, I show how love undergirds moral courage by activating deep emotional bonds and transforming them into action-oriented commitments that transcend fear and self-interest. …

Promethia 2024-2025

Promethia

No abstract provided.

The Geological And Geomorphological Setting Of The Early Bronze Age Site At Ashqelon, Afridar, Eldad Barzilay

'Atiqot

No abstract provided.

The Metallurgical Remains From Ashqelon, Afridar—Areas E, G And H, Irena Segal, Ludwig Halicz, Andrei Kamenski

'Atiqot

No abstract provided.

Animal Exploitation At Early Bronze Age Ashqelon, Afridar: What The Bones Tell Us—Initial Analysis Of The Animal Bones From Areas E, F And G, Sarah Whitcher Kansa

'Atiqot

No abstract provided.

The Butchered Animal Bone Remains From Ashqelon, Afridar—Area G, Haskel J. Greenfield

'Atiqot

No abstract provided.

An Excavation At Ashqelon, Afridar—Area J, Ya‘Aqov Y. Baumgarten

'Atiqot

No abstract provided.

Front Matter, Editorial Board

'Atiqot

No abstract provided.

Excavations At Ashqelon, Afridar—Introduction, Ram Gophna

'Atiqot

No abstract provided.