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Beyond Suprematism: Carpenter Ii And The Reimagining Of The Peasant In Malevich's Late Work, Elizabeth Leslie Lancaster Jul 2025

Beyond Suprematism: Carpenter Ii And The Reimagining Of The Peasant In Malevich's Late Work, Elizabeth Leslie Lancaster

Theses

Every artistic creation is influenced by the dynamics of its origins and the specific intentions of both the artist and the audience to interact with it in a particular way. In abstract art, human elements may be less apparent than in representational art, where recognizable imagery can be more readily linked to the cultural backdrop of its time. Kazimir Malevich’s body of work can superficially be divided into representational pieces and non-objective works. However, a more nuanced interpretation of his oeuvre is warranted. This is particularly relevant to Malevich’s enduring engagement with the peasant motif and the layers of influence …


Engraving Goddesses: Hendrick Goltzius’S Mannerist Prints, Emily Seils Jul 2025

Engraving Goddesses: Hendrick Goltzius’S Mannerist Prints, Emily Seils

Theses

This project analyzes the reception of Hendrick Goltzius’s (1558-1617) prints within the court of Emperor Rudolf II (1552-1612), specifically how his technical expertise in his mythological compositions presented bodily transformation as an alchemical act. He produced images that were intellectually coded for a sophisticated audience while simultaneously capturing the viewer’s gaze and emotions. In doing so he created, alongside his contemporaries, a niche market of high demand art and enabled the "viral" circulation of collectable prints among Northern European elites. Three main topics structured my approach. First, the distinctive development of Rudolf II of Prague’s prestigious art collection, the Kunstkammer, …


Through A Mother's Eyes: The Psychology Of Color, Katie Kutz Jul 2025

Through A Mother's Eyes: The Psychology Of Color, Katie Kutz

Theses

This project investigates the intersection of color psychology, maternal experience, and visual perception through a series of five artworks. Using a qualitative methodology, this project draws upon interdisciplinary research such as neuroscience, marketing, art history, and personal experiences as a mother. This work explores how sensory changes during pregnancy and postpartum influence the emotional perception of color, and how this can be represented in art. Inspired by artists that have explored the theme of motherhood such as Mary Cassatt, Käthe Kollwitz, Paula Modersohn-Becker, Jenny Saville, and Alice Neel, this project uses an emotionally charged approach to depicting motherhood. Color changing …


The Relationships Between Higher Education Institutions And High School Sports Associations: Maximizing Symbiotic Relationships For Teaching Sports Communication, Joseph R. Blaney Ph.D., Livvi Anderson, Evan R. Craig Jul 2025

The Relationships Between Higher Education Institutions And High School Sports Associations: Maximizing Symbiotic Relationships For Teaching Sports Communication, Joseph R. Blaney Ph.D., Livvi Anderson, Evan R. Craig

Faculty Publications - Communications

In this exploratory study of High School Sports Associations (HSSAs) and theirrelationships with sports communication programs at Higher Education Institutions (HEIs), investigators discovered that the associations very broadly see the benefit of establishing mutually beneficial relationships. In its most helpful form, the relationships create Experiential Learning (EL) opportunities which give college students an advantage in a competitive industry while simultaneously helping associations staC the myriad and growing programming events and content platforms. The varying roles available to students, the process behind developing the relationships, and the barriers to creating such relationships are also explored.


#Taxback? Prohibiting State Real Property Taxes On Land In Indian Country, Pippa Browde Jul 2025

#Taxback? Prohibiting State Real Property Taxes On Land In Indian Country, Pippa Browde

Faculty Law Review Articles

Land is a critical asset of Indian tribes. As tribes wrestle with how to create sustainable economies to support their sovereignty, the use and management of tribal land is integral. Taxation is a key component of economic development. This Article is about taxation of land within Indian country. It considers existing law that allows for state taxation of some land within Indian country. It makes a normative claim as to who the proper taxing sovereign should be based on tax policy principles and principles that support tribal self-governance and tribal sovereignty.

In Part II, this Article provides the background for …


Mpo Citizens’ Advisory Committee Training Across Florida, Tia Boyd, Taylor Dinehart, Jeff Kramer Jul 2025

Mpo Citizens’ Advisory Committee Training Across Florida, Tia Boyd, Taylor Dinehart, Jeff Kramer

CUTR Internal Grant Research Program

Federal law and guidance require Metropolitan Planning Organizations (MPOs) to involve the public in the comprehensive, cooperative, and continuing (3C) transportation planning process (see 23 CFR Subpart C § 450.316). Additionally, Florida statute s. 339.175 F.S. further requires that all MPOs in Florida have a citizens’ advisory committee (CAC) or an alternative program or mechanism to ensure citizen involvement in the transportation planning process.

CAC members often have an interest in transportation, but they may lack a foundational understanding of transportation planning processes, MPOs, or the roles and duties of the CAC. Training can help fill these knowledge gaps and …


Editorial – July 2025, Edwin Van Teijlingen, Abeer Musaddique, Rafat Jan Jul 2025

Editorial – July 2025, Edwin Van Teijlingen, Abeer Musaddique, Rafat Jan

Journal of Asian Midwives (JAM)

No abstract provided.


Masthead & Table Of Contents Jul 2025

Masthead & Table Of Contents

Dalhousie Law Journal

No abstract provided.


Racial Capitalism, Neocolonial Wealth Transfer, And Canadian International Student Policy, Vincent Wong, Arman Sohi Jul 2025

Racial Capitalism, Neocolonial Wealth Transfer, And Canadian International Student Policy, Vincent Wong, Arman Sohi

Dalhousie Law Journal

This paper examines historical and contemporary trends in Canadian international student policy through the lens of racial capitalism, arguing that current policy facilitates a significant neocolonial wealth transfer from Global South families to Canada through processes of expropriation, exploitation, and expulsion. It argues that discriminatory tuition fees effectively function as “education head taxes”, which extract billions of dollars annually from international students. Meanwhile, “gauntlets” to permanent residency have emerged in an immigration landscape where working class migrants have narrower options to regularize, creating a system of labour exploitation where student-labourers face precarious conditions and structural indebtedness. Finally, the constant threat …


Re-Reading Power Inside The Aml-Ctf Regime, Sanaa Ahmed Jul 2025

Re-Reading Power Inside The Aml-Ctf Regime, Sanaa Ahmed

Dalhousie Law Journal

Money laundering and money laundering controls are having a global moment. Many jurisdictions around the world—some more than others—feature regularly in news cycles for either offences to do with money laundering or sanctions avoidance or the laxity of controls that enable such activities. The mainstream media has reported on stories about banks in Canada and football clubs in Italy, about charities in the UK and the real estate industry in the US. Each revelation prompts mea culpas from offenders—TD Bank in Canada is one such example—and often, a raft of new or enhanced regulatory measures.

Critically, the point that remains …


Evaluating The Impact Of The Occupation-Centered Intervention Assessment On Client-Centered Care In Inpatient Brain Injury Rehabilitation: A Pilot Study, Vanessa D. Jewell, Katherine Lally, Melinda Schultze, Yongyue Qi, Kendra Schnack, Madeline Mcgill, Rachel Vaughn Jul 2025

Evaluating The Impact Of The Occupation-Centered Intervention Assessment On Client-Centered Care In Inpatient Brain Injury Rehabilitation: A Pilot Study, Vanessa D. Jewell, Katherine Lally, Melinda Schultze, Yongyue Qi, Kendra Schnack, Madeline Mcgill, Rachel Vaughn

Translational Science in Occupation

Background: Occupational therapy practitioners (OTPs) recognize the value of evidence-based practice, however, incorporation of client-centered practice as a component of evidence-based practice is challenging, despite the known advantages. This pilot study evaluated the use of the Occupation Centered Intervention Assessment (OCIA) in increasing practitioner ability to provide client-centered care in inpatient rehabilitation facilities with adults with an acquired brain injury (ABI).

Method: A mixed methods design was employed, using four forms of data collection (OCIA, The Measure of Processes of Care for Service Providers [MPOC], MPOC- Service Providers [MPOC-SP], and interviews) to determine changes in observed and perceived …


Enhancing Diversity In Occupational Therapy Through A High School Internship Program, Alexis M. F. Morin, Brittany Adams, Vianni Gomez Jul 2025

Enhancing Diversity In Occupational Therapy Through A High School Internship Program, Alexis M. F. Morin, Brittany Adams, Vianni Gomez

Translational Science in Occupation

Abstract

The United States (US) is projected to become an increasingly diverse nation over the decades ahead, but there is a lack of racial, ethnic, and gender diversity in occupational therapy (OT). While the job outlook for occupational therapy practitioners continues to be strong and is expected to rise, OT education programs are facing enrollment crises nationally. It is crucial for academic programs to develop and implement innovative and methodical strategies to recruit and retain a diverse student body to promote diversity, inclusion, and equity within the profession. To promote diversity, inclusion, and equity in occupational therapy, a university partnership …


Sabin Center For Climate Change Law Annual Report 2024-2025, Tiffany Challe Jul 2025

Sabin Center For Climate Change Law Annual Report 2024-2025, Tiffany Challe

Sabin Center for Climate Change Law

This 2024-2025 annual report highlights the Sabin Center’s breadth and impact across our program areas, including climate litigation, carbon management and negative emissions technologies, US climate policy, energy transition, climate law and finance.


Defining Identity: Black Women's Personhood As Examined In Sula, The Secret Lives Of Church Ladies, And Sister Citizen: Shame, Stereotypes, And Black Women In America, Taylor King Jul 2025

Defining Identity: Black Women's Personhood As Examined In Sula, The Secret Lives Of Church Ladies, And Sister Citizen: Shame, Stereotypes, And Black Women In America, Taylor King

Theses (2016-Present)

My thesis illustrates the components of Black womanhood within Sula by Toni Morrison and The Secret Lives of Church Ladies by Deesha Philyaw through the political theories of Sister Citizen: Shame, Stereotypes, and Black Women in America, by Melissa V. Harris-Perry. These three works reiterate the multifacetedness of Black identity, specifically Black women in the United States of America. Through textual analysis of these works I examine the stereotypes, struggles, and experiences of motherhood, spirituality, and identity within each work and how slavery and racism impact many African American women. In Sula, The Secret Lives of Church Ladies, and Sister …


Call It When You See It: Major League Soccer Organization And Pediatric Hospital Team Up For Anti-Bullying Program., Ram Chettiar Jul 2025

Call It When You See It: Major League Soccer Organization And Pediatric Hospital Team Up For Anti-Bullying Program., Ram Chettiar

Manuscripts, Articles, Book Chapters and Other Papers

Bullying remains a widespread social issue in the United States (US). Those who bully, are bullied, or witness bullying may experience negative emotional and physical consequences.1 To address the gap in accessible youth bullying interventions, Children's Mercy Kansas City partnered with Sporting Kansas City to develop Red Card KC, a bullying awareness program focusing on the impact of bystanders in bullying situations. The program is delivered to school and community partners through interactive assemblies educating youth on recognizing bullying, managing bullying situations, and standing up against bullying. Red Card KC has also partnered with schools to recognize and celebrate students …


Psychosocial Supports For The Physical And Mental Health Of Youth With Autism And Other Neurodevelopmental Disabilities., Melissa Campbell, Elizabeth Hastings, Paige Mcardle, Darren Olsen, Kathryn Benton, Cy Nadler Jul 2025

Psychosocial Supports For The Physical And Mental Health Of Youth With Autism And Other Neurodevelopmental Disabilities., Melissa Campbell, Elizabeth Hastings, Paige Mcardle, Darren Olsen, Kathryn Benton, Cy Nadler

Manuscripts, Articles, Book Chapters and Other Papers

One in six youth has a neurodevelopmental disability (NDD), and autism diagnostic rates continue to rise. Before and after a diagnosis, families need trusted sources of guidance to navigate co-occurring medical and psychological conditions, and to manage unique stressors including transition to adulthood. However, medical professionals from all specialty areas struggle to identify resources to support the complex psychosocial and healthcare needs of these patients and their families. This primer on psychosocial supports for youth with autism will explore the major mental and physical health stressors faced by affected youth and families, and discuss opportunities for primary care and other …


Constantly Connected: What Healthcare Providers Need To Know About Vicarious Trauma In An Evolving Digitally Connected Global Community., Meghan Kanya, Patricia Davis, Gail Robertson Jul 2025

Constantly Connected: What Healthcare Providers Need To Know About Vicarious Trauma In An Evolving Digitally Connected Global Community., Meghan Kanya, Patricia Davis, Gail Robertson

Manuscripts, Articles, Book Chapters and Other Papers

Easy access to streaming news and sensational headlines has transformed society's exposure to traumatic narratives. From personal stories on social media platforms to news articles about violence in communities, patients and their caregivers may not recognize their exposure as traumatic nor recognize their psychological sequalae as unhealthy. In addition, youth with trauma-related mental health symptoms are not consistently identified in pediatric primary care clinics. Due to the increase in proximity to traumatic stories, healthcare providers working with youth require additional skills designed to engage patients and families in conversations about exposure to violence via technology and symptoms of vicarious trauma. …


Screens Are Not The Enemy: Recommendations For Developing Healthy Digital Habits In Youth., Megan B. Bolch, Rachel Moore, Gail Robertson, Meredith J. Scafe, Libby Milkovich Jul 2025

Screens Are Not The Enemy: Recommendations For Developing Healthy Digital Habits In Youth., Megan B. Bolch, Rachel Moore, Gail Robertson, Meredith J. Scafe, Libby Milkovich

Manuscripts, Articles, Book Chapters and Other Papers

With the rapid and ever-evolving growth of both digital media platforms and mental health concerns in youth, parents and practitioners are faced with the challenge of critically evaluating the effects of digital media use on youth development.1 Despite popular culture's narrow focus on the risks, research has established both positive and negative effects of youth digital media use.2,3 In contrast to interventions primarily focused on screen time limits, the goal of this article is to propose a framework for healthy digital habits rooted in a social-ecological model, called the Multisystemic Model of Digital Habits. This framework considers the intersection of …


Letter Of Concern From The Association Of Academic Chairs Of Emergency Medicine Regarding Acgme Proposed Changes., Richard J. Hamilton, Lance B. Becker, Richard E. Wolfe, D Adam Algren, Thomas Arnold, Michael Baumann, Ross P. Berkeley, Terrell S. Caffery, Chad M. Cannon, Theodore J. Corbin, Michael E. Chansky, Harinder S. Dhindsa, Charles L. Emerman, David A. Farcy, Chris Fox, Michael A. Gibbs, Christopher S. Goode, Steven Andy Godwin, Dietrich Jehle, David Johnson, Samuel M. Keim, Babak Khazaeni, Barry J. Knapp, Clint Hawthorne, John D. Hoyle, Michael Christopher Kurz, Evan Leibner, Robert Mcnamara, Robert F. Mccormack, Edward A. Michelson, Chadwick Miller, Ashley Norse, Andrew Nugent, Brian J. O'Neil, David T. Overton, Edward A. Panacek, William F. Paolo, Denis R. Pauzé, Amanda L. Perez, Ralph J. Riviello, Scott W. Rodi, Peter S. Pang, Juan A. Gonzalez Sanchez, David Seaberg, Adam Schwartz, Stephen A. Shiver, David P. Sklar, Ben C. Smith, Jeffrey R. Stowell, Marc D. Squillante, J Jeremy Thomas, Terry Vanden Hoek, Gregory A. Volturo, E Lea Walters, Thomas E. Wyatt, Donald M. Yealy Jul 2025

Letter Of Concern From The Association Of Academic Chairs Of Emergency Medicine Regarding Acgme Proposed Changes., Richard J. Hamilton, Lance B. Becker, Richard E. Wolfe, D Adam Algren, Thomas Arnold, Michael Baumann, Ross P. Berkeley, Terrell S. Caffery, Chad M. Cannon, Theodore J. Corbin, Michael E. Chansky, Harinder S. Dhindsa, Charles L. Emerman, David A. Farcy, Chris Fox, Michael A. Gibbs, Christopher S. Goode, Steven Andy Godwin, Dietrich Jehle, David Johnson, Samuel M. Keim, Babak Khazaeni, Barry J. Knapp, Clint Hawthorne, John D. Hoyle, Michael Christopher Kurz, Evan Leibner, Robert Mcnamara, Robert F. Mccormack, Edward A. Michelson, Chadwick Miller, Ashley Norse, Andrew Nugent, Brian J. O'Neil, David T. Overton, Edward A. Panacek, William F. Paolo, Denis R. Pauzé, Amanda L. Perez, Ralph J. Riviello, Scott W. Rodi, Peter S. Pang, Juan A. Gonzalez Sanchez, David Seaberg, Adam Schwartz, Stephen A. Shiver, David P. Sklar, Ben C. Smith, Jeffrey R. Stowell, Marc D. Squillante, J Jeremy Thomas, Terry Vanden Hoek, Gregory A. Volturo, E Lea Walters, Thomas E. Wyatt, Donald M. Yealy

Manuscripts, Articles, Book Chapters and Other Papers

This letter, signed by over 50 academic chairs of emergency medicine, urges the ACGME to reconsider a proposed mandate requiring all emergency medicine residency programs to adopt a four-year training model. The authors argue that current three-year programs are supported by data demonstrating equivalent educational and clinical outcomes compared to four-year formats. They criticize the flawed survey methodology underpinning the proposal, note the loss of milestone-based training flexibility, and highlight the lack of added scholarly or clinical value in the fourth year. The letter also outlines negative consequences for fellowship participation, workforce development, trainee debt, and diversity. The signatories advocate …


Characterizing Long Covid Symptoms During Early Childhood., Rachel S. Gross, Tanayott Thaweethai, Amy L. Salisbury, Lawrence C. Kleinman, Sindhu Mohandas, Kyung E. Rhee, Jessica N. Snowden, Kelan G. Tantisira, David Warburton, John C. Wood, Patricia A. Kinser, Joshua D. Milner, Erika B. Rosenzweig, Katherine Irby, Valerie J. Flaherman, Elizabeth W. Karlson, Lori B. Chibnik, Deepti B. Pant, Aparna Krishnamoorthy, Richard Gallagher, Michelle F. Lamendola-Essel, Denise C. Hasson, Stuart D. Katz, Shonna Yin, Benard P. Dreyer, Frank Blancero, Megan Carmilani, K Coombs, Megan L. Fitzgerald, Rebecca J. Letts, Aimee K. Peddie, Judy L. Aschner, Andrew M. Atz, Dithi Banerjee, Amanda Bogie, Hulya Bukulmez, Katharine Clouser, Lesley A. Cottrell, Kelly Cowan, Viren A. D'Sa, Allen Dozor, Amy J. Elliott, E Vincent S. Faustino, Alexander G. Fiks, Sunanda Gaur, Maria L. Gennaro, Stewart Gordon, Uzma N. Hasan, Christina M. Hester, Alexander Hogan, Daniel S. Hsia, David C. Kaelber, Jessica S. Kosut, Sankaran Krishnan, Russell J. Mcculloh, Ian C. Michelow, Sheila M. Nolan, Carlos R. Oliveira, Lynn M. Olson, Wilson D. Pace, Paul Palumbo, Hengameh Raissy, Andy Reyes, Judith L. Ross, Juan C. Salazar, Rangaraj Selvarangan, Cheryl R. Stein, Michelle D. Stevenson, Ronald J. Teufel, Alan Werzberger, John M. Westfall, Kathleen Zani, William T. Zempsky, Emily Zimmerman, Marie-Abele C. Bind, James Chan, Zoe Guan, Richard E. Morse, Harrison T. Reeder, Torri D. Metz, Jane W. Newburger, Dongngan T. Truong, Andrea S. Foulkes, Melissa S. Stockwell, Recover-Pediatrics Consortium, Recover-Pediatrics Group Authors Jul 2025

Characterizing Long Covid Symptoms During Early Childhood., Rachel S. Gross, Tanayott Thaweethai, Amy L. Salisbury, Lawrence C. Kleinman, Sindhu Mohandas, Kyung E. Rhee, Jessica N. Snowden, Kelan G. Tantisira, David Warburton, John C. Wood, Patricia A. Kinser, Joshua D. Milner, Erika B. Rosenzweig, Katherine Irby, Valerie J. Flaherman, Elizabeth W. Karlson, Lori B. Chibnik, Deepti B. Pant, Aparna Krishnamoorthy, Richard Gallagher, Michelle F. Lamendola-Essel, Denise C. Hasson, Stuart D. Katz, Shonna Yin, Benard P. Dreyer, Frank Blancero, Megan Carmilani, K Coombs, Megan L. Fitzgerald, Rebecca J. Letts, Aimee K. Peddie, Judy L. Aschner, Andrew M. Atz, Dithi Banerjee, Amanda Bogie, Hulya Bukulmez, Katharine Clouser, Lesley A. Cottrell, Kelly Cowan, Viren A. D'Sa, Allen Dozor, Amy J. Elliott, E Vincent S. Faustino, Alexander G. Fiks, Sunanda Gaur, Maria L. Gennaro, Stewart Gordon, Uzma N. Hasan, Christina M. Hester, Alexander Hogan, Daniel S. Hsia, David C. Kaelber, Jessica S. Kosut, Sankaran Krishnan, Russell J. Mcculloh, Ian C. Michelow, Sheila M. Nolan, Carlos R. Oliveira, Lynn M. Olson, Wilson D. Pace, Paul Palumbo, Hengameh Raissy, Andy Reyes, Judith L. Ross, Juan C. Salazar, Rangaraj Selvarangan, Cheryl R. Stein, Michelle D. Stevenson, Ronald J. Teufel, Alan Werzberger, John M. Westfall, Kathleen Zani, William T. Zempsky, Emily Zimmerman, Marie-Abele C. Bind, James Chan, Zoe Guan, Richard E. Morse, Harrison T. Reeder, Torri D. Metz, Jane W. Newburger, Dongngan T. Truong, Andrea S. Foulkes, Melissa S. Stockwell, Recover-Pediatrics Consortium, Recover-Pediatrics Group Authors

Manuscripts, Articles, Book Chapters and Other Papers

IMPORTANCE: Recent studies have identified characteristic symptom patterns of long COVID (LC) in adults and children older than 5 years. However, LC remains poorly characterized in early childhood. This knowledge gap limits efforts to identify, care for, and prevent LC in this vulnerable population.

OBJECTIVES: To identify symptoms that had the greatest difference in frequency comparing children with a history of SARS-CoV-2 infection to those without, to identify differences in the types of symptoms by age group (infants/toddlers [0-2 years] vs preschool-aged children [3-5 years]), and to derive an index that can be used in research studies to identify young …


Spatial Clustering Of Immunosuppressive Macrophages In Papillary Renal Cell Carcinoma, Mitchell T. Hayes, Jose Laborde, Alex Soupir, Anders Berglund, Jamie K. Teer, Kirill Sabitov, Nicholas H. Chakiryan, Taylor C. Peak, Jonathan Nguyen, Carlos Moran-Segura, Daryoush Saeed-Vafa, Neale Lopez-Blanco, Martina Molgora, Paola M. Ramos-Echevarria, Christopher Guske, Jodi Balasi, Jasreman Dhillon, Youngchul Kim, James Mule, Brooke L. Fridley, Brandon J. Manley Jul 2025

Spatial Clustering Of Immunosuppressive Macrophages In Papillary Renal Cell Carcinoma, Mitchell T. Hayes, Jose Laborde, Alex Soupir, Anders Berglund, Jamie K. Teer, Kirill Sabitov, Nicholas H. Chakiryan, Taylor C. Peak, Jonathan Nguyen, Carlos Moran-Segura, Daryoush Saeed-Vafa, Neale Lopez-Blanco, Martina Molgora, Paola M. Ramos-Echevarria, Christopher Guske, Jodi Balasi, Jasreman Dhillon, Youngchul Kim, James Mule, Brooke L. Fridley, Brandon J. Manley

Manuscripts, Articles, Book Chapters and Other Papers

Background

Papillary renal cell carcinoma (pRCC) is the second most common kidney cancer subtype, yet our understanding of its tumor immune microenvironment (TIME) remains limited.

Objective

We utilized multiplex immunofluorescence (mIF) and spatial transcriptomics (ST) to evaluate immune cell architecture in pRCC contrasted with clear cell RCC (ccRCC).

Methods

Localized RCC tumors (16 pRCC, 70 ccRCC) underwent mIF using markers for T cells, B cells, and tumor-associated macrophages (TAMs). Spatial data in both tumor and stromal compartments of the TIME were collected. A post hoc recurrence free survival analysis (RFS) was performed using Cox proportional hazard models. Single-cell ST was …


What Is The Expected Clearance Of Methotrexate? A Therapeutic Drug Monitoring Reference Guide For High-Dose Methotrexate Use In Pediatric Malignancies., Zachary L. Taylor, Tamara P. Miller, Sarah G. Board, Ethan Poweleit, Ashley Chavana, Allison Weisnicht, Austin L. Brown, Melanie B. Bernhardt, Eric S. Schafer, Maureen M. O'Brien, Sharon M. Castellino, Laura Ramsey Jul 2025

What Is The Expected Clearance Of Methotrexate? A Therapeutic Drug Monitoring Reference Guide For High-Dose Methotrexate Use In Pediatric Malignancies., Zachary L. Taylor, Tamara P. Miller, Sarah G. Board, Ethan Poweleit, Ashley Chavana, Allison Weisnicht, Austin L. Brown, Melanie B. Bernhardt, Eric S. Schafer, Maureen M. O'Brien, Sharon M. Castellino, Laura Ramsey

Manuscripts, Articles, Book Chapters and Other Papers

High-dose methotrexate dosage and infusion durations differ across treatment protocols for pediatric leukemia, lymphoma, and osteosarcoma. Supportive care interventions are dependent on a patient's elimination of methotrexate (MTX). Therefore, it is important to establish the expected MTX elimination across protocols. Using modeling and simulation of real-world data, we determined the expected MTX concentrations at common time points from the start of infusion (24, 36, 42, 48, 60, and 72 hours) and the time that each patient would reach a typical discharge threshold (0.4, 0.2, 0.15, and 0.10 µM). These data provide a reference for MTX concentrations for common pediatric protocols.


Daily Physical Activity And Cardiorespiratory Fitness In Adults With Down Syndrome With And Without Congenital Heart Disease., Julianne G. Clina, David A. White, Joseph R. Sherman, Jessica C. Danon, Daniel Forsha, Brian C. Helsel, Richard A. Washburn, Joseph E. Donnelly, Lauren T. Ptomey Jul 2025

Daily Physical Activity And Cardiorespiratory Fitness In Adults With Down Syndrome With And Without Congenital Heart Disease., Julianne G. Clina, David A. White, Joseph R. Sherman, Jessica C. Danon, Daniel Forsha, Brian C. Helsel, Richard A. Washburn, Joseph E. Donnelly, Lauren T. Ptomey

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Individuals with Down syndrome (DS) typically exhibit lower cardiorespiratory fitness and reduced moderate-to-vigorous physical activity (MVPA) compared to persons without disability. Approximately 50-55 % of individuals with DS have congenital heart disease (CHD), which is associated with cardiopulmonary deficiencies and reduced MVPA participation in non-DS populations. It is unknown if CHD related comorbidities compound with DS associated deficits in physical activity and fitness.

OBJECTIVE: To compare physical activity, cardiorespiratory fitness, and cardiovascular function, of persons with DS with and without CHD.

METHODS: Baseline data were used from a 12-month randomized controlled physical activity intervention of adults with DS. Participants …


Volumetric And Diffusion Tensor Imaging Abnormalities Are Associated With Behavioral Changes Post-Concussion In A Youth Pig Model Of Mild Traumatic Brain Injury., Sanjida Islam, Alesa Netzley, Chenyang Li, Jiangyang Zhang, Bianca Dávila-Montero, Ana Vazquez, Shaun Subbaiah, Avner Moeded, Kirk Munoz, Aimee Colbath, Jie Huang, Ricardo Mejia-Alvarez, Jane Manfredi, Galit Pelled Jul 2025

Volumetric And Diffusion Tensor Imaging Abnormalities Are Associated With Behavioral Changes Post-Concussion In A Youth Pig Model Of Mild Traumatic Brain Injury., Sanjida Islam, Alesa Netzley, Chenyang Li, Jiangyang Zhang, Bianca Dávila-Montero, Ana Vazquez, Shaun Subbaiah, Avner Moeded, Kirk Munoz, Aimee Colbath, Jie Huang, Ricardo Mejia-Alvarez, Jane Manfredi, Galit Pelled

Manuscripts, Articles, Book Chapters and Other Papers

Mild traumatic brain injury (mTBI) caused by sports-related incidents in children and youth often leads to prolonged cognitive impairments but remains difficult to diagnose. In order to identify clinically relevant imaging and behavioral biomarkers associated concussion, a closed-head mTBI was induced in adolescent pigs. Twelve (n = 4 male and n = 8 female), 16-week old Yucatan pigs were tested; n = 6 received mTBI and n = 6 received a sham procedure. T1-weighted imaging was used to assess volumetric alterations in different regions of the brain and diffusion tensor imaging (DTI) to examine microstructural damage in white matter. The …


Leveraging Chorionic Villus Biopsies For The Derivation Of Patient-Specific Trophoblast Stem Cells., Kaela Varberg, Ayelen Moreno-Irusta, Allynson Novoa, Brynne Musser, Joseph M. Varberg, Jeremy P. Goering, Irfan Saadi, Khursheed Iqbal, Hiroaki Okae, Takahiro Arima, John Williams, Margareta D. Pisarska, Michael J. Soares Jul 2025

Leveraging Chorionic Villus Biopsies For The Derivation Of Patient-Specific Trophoblast Stem Cells., Kaela Varberg, Ayelen Moreno-Irusta, Allynson Novoa, Brynne Musser, Joseph M. Varberg, Jeremy P. Goering, Irfan Saadi, Khursheed Iqbal, Hiroaki Okae, Takahiro Arima, John Williams, Margareta D. Pisarska, Michael J. Soares

Manuscripts, Articles, Book Chapters and Other Papers

Human trophoblast stem (TS) cells are informative in vitro models for the generation and testing of biologically meaningful hypotheses. The goal of this project was to derive patient-specific TS cell lines from clinically available chorionic villus biopsies. Cell outgrowths were captured from human chorionic villus tissue specimens cultured in modified human TS cell medium. Cell colonies emerged early during the culture and cell lines were established and passaged for several generations. Karyotypes of the newly established chorionic villus-derived trophoblast stem (TSCV) cell lines were determined and compared to initial genetic diagnoses from freshly isolated chorionic villi. Phenotypes of …


The Pediatric Experience Collaborative: Paving The Way In Pediatric Experience., Lauren Hamilton, Trenton House, Taylor B. Sewell, Harris Baden, Brianna Combs, Sara L. Toomey, Shehzad Saeed, Jana Rojas, Molly Warneke, Maureen Hoff, Andréa Aken'ova, Lisa Rubino, Dana Ileana Williams, Samuel P. Hanke Jul 2025

The Pediatric Experience Collaborative: Paving The Way In Pediatric Experience., Lauren Hamilton, Trenton House, Taylor B. Sewell, Harris Baden, Brianna Combs, Sara L. Toomey, Shehzad Saeed, Jana Rojas, Molly Warneke, Maureen Hoff, Andréa Aken'ova, Lisa Rubino, Dana Ileana Williams, Samuel P. Hanke

Manuscripts, Articles, Book Chapters and Other Papers

Positive patient experience is associated with improved patient outcomes, but efforts to improve patient experience are often underprioritized, especially with respect to pediatric care. To address this challenge, leaders at several US children's hospitals established the Pediatric Experience Collaborative (PEC) in 2016 to leverage their collaboration and scale to optimize patient, family, and provider experiences. Since then, the PEC has steadfastly incorporated the patient and family perspective in all its endeavors (e.g., installing a family member as one of the organization's co-chairs); has created both structured opportunities and unstructured opportunities for learning and connection; and has embarked on multi-institutional research …


Sex Differences In Motor Unit Behavior In Patients With Parkinson's Disease, Yuichi Nishikawa, Kohei Watanabe, Aleš Holobar, Tetsuya Takahashi, Noriaki Maeda, Hirofumi Maruyama, Allison Hyngstrom Jul 2025

Sex Differences In Motor Unit Behavior In Patients With Parkinson's Disease, Yuichi Nishikawa, Kohei Watanabe, Aleš Holobar, Tetsuya Takahashi, Noriaki Maeda, Hirofumi Maruyama, Allison Hyngstrom

Physical Therapy Faculty Research and Publications

The aim of this study was to determine whether there are sex differences in motor unit firing behavior in patients with Parkinson's disease. Twenty-seven patients with Parkinson's disease (females = 14 [age = 71.1 ± 6.8], males = 13 [age = 69.2 ± 10.3], Unified Parkinson's Disease Rating Scale Part III score; females = 10.8 ± 4.8, males = 11.4 ± 1.4) performed a contraction at 30% of the maximal voluntary contraction. For each participant, motor unit spike trains were decomposed from high-density surface electromyography data recorded from bilateral vastus lateralis muscles via blind source separation algorithms. In addition to …


Electrochemistry Behind Pfas: Mechanistic And Analytical Approach For Sensing And Degradation Strategies, Jonathan Josue Calvillo Solis Jul 2025

Electrochemistry Behind Pfas: Mechanistic And Analytical Approach For Sensing And Degradation Strategies, Jonathan Josue Calvillo Solis

Open Access Theses & Dissertations

Understanding the fundamental electrochemistry of perfluoroalkyl substances (PFAS) is key to developing effective water remediation and sensing strategies. This work explores the thermodynamics and kinetics of perfluorooctanoic acid (PFOA) electroreduction, focusing on C-F bond cleavage. These insights were applied to design a highly sensitive electrochemical sensor for detecting trace levels of PFOA in water. This dissertation focuses on the electrochemical investigation of the reduction reaction of PFOA in aqueous and organic media employing different electrode materials. This exploration allows to understand the defluorination reaction of PFAS to further propose potential strategies for water treatment and PFOA electrosensing. Through electrochemical, spectroscopical …


Research Nexus : Volume 27 - 2025, Office Of Research And Graduate Studies Jul 2025

Research Nexus : Volume 27 - 2025, Office Of Research And Graduate Studies

Office of Research and Graduate Studies

  • Researcher Spotlight
  • Research Milestones & News
  • Capacity Building Initiatives
  • Upcoming Training & Webinars


Finir: The 2nd Workshop On Financial Information Retrieval In The Era Of Generative Ai, Fengbin Zhu, Yunshan Ma, Fuli Feng, Chao Wang, Huanbo Luan, Guangnan Ye, Shuo Zhang, Dhagash Mehta, Pingping Chen, Bing Xiang, Tat‑Seng Chua Jul 2025

Finir: The 2nd Workshop On Financial Information Retrieval In The Era Of Generative Ai, Fengbin Zhu, Yunshan Ma, Fuli Feng, Chao Wang, Huanbo Luan, Guangnan Ye, Shuo Zhang, Dhagash Mehta, Pingping Chen, Bing Xiang, Tat‑Seng Chua

Research Collection School Of Computing and Information Systems

Recent advancements in Generative AI, such as Large Language Models (LLMs), have demonstrated remarkable success across various general tasks. Extensive studies have explored leveraging generative models in finance, but significant challenges persist. This half-day workshop explores potential approaches and research directions to address these challenges by equipping generative models with advanced Information Retrieval (IR) models. Specifically, this workshop seeks to provide a platform for discussing innovative ideas that facilitate the advancement of IR technology to enrich generative models in finance from four key perspectives: (i) financial IR techniques (ii) financial IR benchmarking and evaluation (iii) financial systems and agents/assistants (iv) …