Digital Commons Network^™

Delayed Presentation Of A Retained Colonic Segment In A Child With Intestinal Failure On Teduglutide, Rachel C Bordelon, Sarah J Varalla, Varaha S Tammisetti, Mohamed M Shahin, Amanda Tchakarov, Essam Imseis, Allison L Speer

Faculty, Staff and Student Publications

Teduglutide is a glucagon-like peptide 2 (GLP-2) analogue that was approved by the United States Food and Drug Administration for the treatment of pediatric (>1 year) intestinal failure due to short bowel syndrome in 2019. GLP-2 analogues promote rapid intestinal adaptation, increasing the absorptive capacity of residual intestine after surgical resection to aid the achievement of enteral autonomy or reduce parenteral nutrition requirements. Despite relatively few reported side effects, there is a theoretical risk of proliferative complications. Here we present an intriguing case of a pediatric patient found to have a decade-long retained, discontinuous segment of colon from a …

The Mythology Of Polymyositis, Suur Biliciler, Tahseen Mozaffar

Faculty, Staff and Student Publications

Polymyositis (PM) has been in the diagnostic armamentarium in medicine since the mid-nineteenth century. Medicine training puts a heavy emphasis on this diagnosis, and anyone with proximal muscle weakness with elevated serum creatinine kinase is assumed to be PM and a number of patients were rendered this diagnosis without additional testing. This article addresses the historical aspects of the diagnosis of PM and its evolution. We review this literature that addresses the rarity of this diagnosis and rightly puts in perspective in terms of its occurrence in relation to other inflammatory myositides.

Innovations In Thrombectomy Training: A Systematic Review And Expert Recommendations From The Society Of Vascular And Interventional Neurology-Mission Thrombectomy Initiative, Fawaz Al-Mufti, Mohamed Elfil, Abdallah Abbas, Haneen Sabet, Hazem S Ghaith, Ariel Sacknovitz, Ankita Jain, Victor Urrutia, Nabeel Herial, Gabor Toth, Mohamad El-Ghanem, Krishna Amuluru, Viktor C Szeder, Jonathan Crowe, Karol Budohoski, Zurab Nadareishvili, Kaustubh Limaye, Fazeel Siddiqui, Boris Pabon, Ossama Yassin Mansour, Atilla Ozcan Ozdemir, Houman Khosravani, Hamza Shaikh, Nishita Singh, Hesham Masoud, Sushanth R Aroor, Shashvat Desai, Santiago Ortega-Gutierrez, Fredrick Echols, Thanh N Nguyen, Pankajavalli Ramakrishnan, Priyank Khandelwal, Dileep R Yavagal, Kaiz Asif

Faculty, Staff and Student Publications

Background: Mechanical thrombectomy is a critical intervention for patients with acute ischemic stroke with large vessel occlusion. However, significant barriers remain in its widespread implementation, particularly in low- to middle-income countries, including a shortage of trained physicians and limited access to advanced medical technologies. This systematic review and meta-analysis aimed to comprehensively evaluate current mechanical thrombectomy training methodologies and assess their effectiveness in improving procedural skills among neurointerventional teams.

Methods: We conducted a systematic review following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines, searching PubMed, Scopus, and Web of Science. Eight studies were included, with 3 studies eligible …

Depression Polygenicity And Disease Activity And Disability Worsening In Multiple Sclerosis, Ali Manouchehrinia, Kathryn C Fitzgerald, Amber Salter, Ruth Ann Marrie, Lars Alfredsson, Charles N Bernstein, James M Bolton, Gary Cutter, John D Fisk, Lesley A Graff, Carol A Hitchon, Jan Hillert, Ingrid Kockum, Yi Lu, Fred D Lublin, Kyla Mckay, Tomas Olsson, Scott Patten, Amit Patki, Hayley Riel, Klementy Shchetynsky, Pernilla Stridh, Hemant K Tiwari, Jerry S Wolinsky, Kaarina Kowalec

Faculty, Staff and Student Publications

Objective: A better understanding of factors associated with multiple sclerosis (MS) disease activity and disability is needed. Given the strong link between comorbid depression and MS disease activity and disability, we aimed to determine whether the depression genetic burden, as modelled using its polygenic score, is associated with MS disease activity and disability worsening.

Methods: In this cohort study, we used samples from neurologist-defined adult people with MS (PwMS) followed in clinical care or during a clinical trial from existing cohorts: Canada, the United States (US), and Sweden with extensive longitudinal phenotypes. We computed the depression polygenic score (PGS) and …

Prevalence Of Obesity With Confirmed Excess Adiposity In Us Children And Adolescents, Alexandra B Palmer, Kyung Hyun Lee, Rashedeh Roshani, Elizabeth Frankel, Miryoung Lee, Mohammad Y Anwar, Heather M Highland, Kristin L Young, Mariaelisa Graff, Joseph B Mccormick, Susan P Fisher-Hoch, Joyce P Samuel, Jennifer E Below, Kari E North, Penny Gordon-Larsen

Faculty, Staff and Student Publications

No abstract provided.

From Reflex Reaction To Rational Action-Personalizing Surgical Antibiotic Prophylaxis, Renee W Green, William D Rieger, Lillian S Kao

Faculty, Staff and Student Publications

No abstract provided.

Virtual Reality In Esl Teaching And Learning In A Hybrid Learning Environment In The United Arab Emirates, Basma Abdulla Abri

Dissertations

This study examines the impact of Virtual Reality (VR) on the oral proficiency of EFL learners in the UAE context, with exploring the instructors and students’ perspectives on using VR as a language learning tool. The study involved 44 Emirati higher education students enrolled in an English Communications Program divided into a control group using traditional methods, and an experimental group using VR tools for communicative activities. Data collection employed mixed-methods research through questionnaire surveys involving college students and interviews with EFL instructors over a ten-week period. According to the findings, the experimental group demonstrated higher oral proficiency than the …

The Synod: A Journey Through Inculturation To Contextuality, George Worgul

Spiritan Horizons

No abstract provided.

Reading The Word And The World: Overstanding Literacy In Aboriginal And Chinese Classrooms, Gui Ying Annie Yang-Heim

Faculty Publications - College of Education

This qualitative comparative case study examines how culturally grounded philosophies of education shape the teaching and learning of reading in two cross-cultural contexts—an Aboriginal Australian classroom and urban Chinese elementary schools. Drawing on interpretive and reflexive methodologies, it investigates how Aboriginal and Confucian epistemologies influence literacy practices and how these practices align with or resist dominant, decontextualized models of reading instruction. Data sources include classroom observations, reading assessments, teacher interviews, and researcher reflections. Conceptually framed by Gadamer’s hermeneutics, Bourdieu’s theory of cultural capital, Habermas’s typology of knowledge, and the Caribbean concept of overstanding, this research finds that Aboriginal literacy is …

The Reception Of Fiducia Supplicans As Indicative Of The Paths Of Synodality, Chimaobi Clement Emefu Cssp

Spiritan Horizons

No abstract provided.

The Root Cause Of Perceived Appraisal Politics Using Evidence From The South Korean Public Sector, Jinwoong Yoo, Saeyeon Roh, Mohamed Haddoud, Smita Tripathi

Plymouth Business School

The purpose of this study is to investigate the root causes of Perceived Appraisal Politics (PAP) within the public sector in South Korea. Scholars in the field of Human Resource Management (HRM) have identified the determinants of PAP in an effort to mitigate it. However, the complex interactions among those determinants and root causes have been overlooked. Therefore, we adopt a novel methodology in this study that combines Interpretive Structural Modelling (ISM) and fuzzy-Decision-Making Trial and Evaluation Laboratory (f-DEMATEL). The findings indicate that the root causes of PAP include the presence of cliques, ambiguity of appraisal policies and goal ambiguity …

Potentially Toxic Metals, Anthropogenic Microfibres And Other Microplastics In Sediments From A Small, Urban Estuary (Plym, Southwest England), Kwong Ricky Li, Andrew Turner

School of Geography, Earth and Environmental Sciences

Anthropogenic microfibres (AMFs) and microplastics (MPs) are pervasive and ubiquitous environmental contaminants of growing concern. However, their study in geosolids, like sediments, is often conducted in the absence of other important geochemical and anthropogenic markers. In the present study, surface and subsurface sediments from the Plym Estuary, southwest England, have been analysed for AMFs and MPs along with organic matter (as loss on ignition; LOI), calcium, iron, manganese and potentially toxic metals (PTMs). The latter were heterogeneously distributed throughout the estuary because of multiple inputs and variations in sediment granulometry. AMFs were mainly constructed of cellulosic and petroleum-based polymers and …

Hydrogen, Single-Carbon Compounds, And Thermal Regime In The Oceanic Ultramafic-Dominated Lithosphere: Insights From A Deep Borehole On The Atlantis Massif, Susan Q. Lang, C. Geoffrey Wheat, Kristin L. Dickerson, Mark K. Reagan, Ivan P. Savov, Jordyn A. Robare, William J. Brazelton, Johanna Suhonen, Oscar Cavazos, Andrew Mccaig, Peter Blum, Natsue Abe, Rémi Coltat, Jeremy R. Deans, Marguerite Godard, Barbara E. John, Frieder Klein, Rebecca Kuehn, Kuan Yu Lin, C. Johan Lissenberg, Haiyang Liu, Ethan L. Lopes, Toshio Nozaka, William Osborne, Andrew J. Parsons, Vamdev Pathak, Jessica Rodgers, Jeffrey S. Seewald, Kenneth W. Sims, Gordon Southam

School of Geography, Earth and Environmental Sciences

Water that flows through permeable ultramafic rocks produces high abundances of molecular hydrogen (H₂), methane (CH₄), and other small organic molecules. Such products can fuel life in the rocky subseafloor, be extracted for energy, and may have played a role in pre-biological chemical synthesis on early Earth or other planetary bodies. The International Ocean Discovery Program drilled a new 1268-m-deep borehole (U1601C) into serpentinized mantle with minor gabbroic rocks on the Atlantis Massif, ∼800-m north of the Lost City hydrothermal field (30°N, Mid-Atlantic Ridge). Measured temperatures of the disturbed borehole reached 91.3 °C, and equilibrated temperatures …

Model Fatigue: Debugging Hector Through Climate Computational Aesthetics, Helen Pritchard, Guillemette Legrand

School of Art, Design and Architecture

In this paper, we document three computational features of the climate model Hector by translating the modalities through which the model predicts climate futures in a game engine. We build upon the computational aesthetics of M. Beatrice Fazi and Matthew Fuller (2016) and suggest additional characteristics of computation to their proposed list. We argue that these computational aesthetics are essential to climate modelling. The three features are time series, couplings and cosmograms, which are based on our practical and theoretical inquiry into Hector’s computation and literacy. We develop a framework that employs two processual methods: translating the model’s operations into …

Relationship Of Professional Military Education And Generative Artificial Intelligence With Mission Analysis, Pinky A. De Garcia

Ateneo School of Government Publications

The increasing integration of Generative Artificial Intelligence (GenAI) into military education presents opportunities for supporting instructional processes and military decision-making competencies. Previous studies have examined the applications, benefits, and challenges of artificial intelligence in military education and decision-making. However, further investigation is needed to understand how GenAI usage relates to specific competencies developed through Professional Military Education (PME), particularly mission analysis. This study examined the relationship of PME and the frequency of GenAI usage with perceived mission analysis accuracy among 200 purposively selected military personnel. A quantitative, non-experimental approach was employed using descriptive statistics, correlational analysis, and hierarchical regression. The …

(Un)Just Transitions For Youth And The Disabled? The Exclusionary Pressures Facing Science, Technology, Engineering And Mathematics (Stem) Education, Elizabeth Done, Helen Knowler, Irina Lazar, Sylvia Hayes, Joshua Lait, Andrea Perez-Porres

School of Law, Humanities and Social Sciences

This paper highlights the under-representation of young people with disabilities in STEM subjects and career pathways, with particular reference to the engineering sector given its prominent role in the design of energy systems related to net-zero policies. We consider the role of physical infrastructure, and pedagogic and representational practices, in facilitating the marginalisation and under-representation of young people with disabilities. Ultimately, we seek a broader understanding of the ‘just transition’ that acknowledges the role of education in ensuring the active participation of all young people, regardless of learning difficulty or disability or social identity, in that transition. The research is …

Comorbidities And Emotions - Unpacking The Sentiments Of Pediatric Patients With Multiple Long-Term Conditions Through Social Media Feedback: A Large Language Model-Driven Study, Temidayo Oluwalade, Hossein Ahmadi, Lin Huo, Richard Sharpe, Shang-Ming Zhou

School of Nursing and Midwifery

ObjectivesThe emotional and psychological challenges faced by children with multiple long-term conditions (MLTCs) remain underexplored. This study aimed to analyze sentiments and emotions expressed by this vulnerable population and their caregivers on social media, assess the effects of comorbidities and the COVID-19 pandemic on emotional well-being.MethodsNarratives from the Care Opinion platform (2008–2023) were analyzed by a model called CoEmoBERT, developed using the large language model, distilroberta-base transformer model. The CoEmoBERT-based sentiment analysis categorized emotions into “Positive”, “Negative”, and “Neutral,” with further refinements into specific emotions such as “Sad,” “Fear”, “Satisfied” etc. through pretraining and transferring process. Comorbidity associations with emotions …

Risk Factors To Predict Mortality In People With Seizures Reattending Emergency Departments: A Dual-Centre Study, Rohit Shankar, Madeline Dale, Sarah Lennard, William Henley, Brendan Mclean, Mark Jadav, Richard Laugharne, Gurjit Chohan, Sarah Trippier, Laura Sewell, Jamie Ford, Sarah Davis

Peninsula Medical School

Background: Recurrent seizure-related emergency department (ED) attendances are common and associated with poor outcomes. We aimed to identify factors associated with repeated seizure-related ED use and to develop a mortality risk score among individuals re-attending with seizures. Methods: We conducted a retrospective cohort study across two district general hospitals in South-West England, Royal Cornwall Hospitals NHS Trust (RCH; 2015–2018) and Royal United Hospitals Bath NHS Trust (RUH; 2018–2022). Adults (≥18 years) with ≥2 seizure-related ED attendances were included. Negative binomial regression was used to examine demographic and clinical predictors of repeat attendances. A risk score based on these predictors was …

How Do Community Assets Support Health In A Rural Community? An Ethnographic Case Study, Jennie Hayes, Liz Edwards-Smith, Richard Byng, Kerryn Husk, Katrina Wyatt

Peninsula Medical School

Community assets (including voluntary, community, social enterprise and grassroots initiatives) have the potential to help address health inequalities. There is a growing understanding of the importance of putting communities at the heart of public health to improve population health. Understanding the mechanisms by which grassroots activities support health and wellbeing is important for making commissioning decisions, for community confidence and for the purposes of evaluation. This study takes an ethnographic case study approach to explore one rural community in the south-west of England. We observed activities and interactions, had informal conversations with residents and community leaders and conducted focus groups. …

Artificial Intelligence To Detect Developmental Dysplasia Of Hip: A Systematic Review, Suketu Bhavsar, Bhanu B. Gowda, Maulini Bhavsar, Sanjay Patole, Shripada Rao, Chandra Rath

Research outputs 2022 to 2026

Aim: Deep learning (DL), a branch of artificial intelligence (AI), has been applied to diagnose developmental dysplasia of the hip (DDH) on pelvic radiographs and ultrasound (US) images. This technology can potentially assist in early screening, enable timely intervention and improve cost-effectiveness. We conducted a systematic review to evaluate the diagnostic accuracy of the DL algorithm in detecting DDH. Methods: PubMed, Medline, EMBASE, EMCARE, the clinicaltrials.gov (clinical trial registry), IEEE Xplore and Cochrane Library databases were searched in October 2024. Prospective and retrospective cohort studies that included children (< 16 years) at risk of or suspected to have DDH and reported hip ultrasonography (US) or X-ray images using AI were included. A review was conducted using the guidelines of the Cochrane Collaboration Diagnostic Test Accuracy Working Group. Risk of bias was assessed using the QUADAS-2 tool. Results: Twenty-three studies met inclusion criteria, with 15 (n = 8315) evaluating DDH on US images and eight (n = 7091) on pelvic radiographs. The area under the curve of the included studies ranged from 0.80 to 0.99 for pelvic radiographs and 0.90–0.99 for US images. Sensitivity and specificity for detecting DDH on radiographs ranged from 92.86% to 100% and 95.65% to 99.82%, respectively. For US images, sensitivity ranged from 86.54% to 100% and specificity from 62.5% to 100%. Conclusion: AI demonstrated comparable effectiveness to physicians in detecting DDH. However, limited evaluation on external datasets restricts its generalisability. Further research incorporating diverse datasets and real-world applications is needed to assess its broader clinical impact on DDH diagnosis.

Evidence-Informed Propositions For A Whole-Of-Program Assessment Approach, Janica Jamieson, Rachel Bacon, Andrea Bramley, Janeane Dart, Simone Gibson, Gemma Jenkins, Meredith Kennedy, Sue Kleve, Claire Palermo

Research outputs 2022 to 2026

Aim: To develop evidence-informed propositions for implementing whole-of-program assessment across dietetic education settings, in response to emerging education theory, technological advances such as generative artificial intelligence, and the need for meaningful learning and trustworthy progression decisions. Methods: A four-stage multiple methods study, grounded in pragmatism, was conducted. Initial propositions were developed through a systematic scoping review of programmatic assessment literature. Thematic analysis was used to identify patterns, which were iteratively refined into themes and then preliminary propositions. These were further refined through workshops with dietetic educators, who provided feedback based on their expertise. A repeated systematic scoping review incorporated recent …

Mine Tailings As A Sustainable Filler For Asphalt Binder–Mastics: A Review, Daniel O. Oguntayo, Nuha S. Mashaan, Sanjay K. Shukla

Research outputs 2022 to 2026

Sustainability has become a primary focus on a global scale. However, there is a threat to sustainable development due to the substantial generation of waste from urbanization and industrialization. Particularly, the accumulation of mine tailings is a problem, an industrial waste by-product from the mining sector. To support sustainable development and promote circular economy, it is imperative to utilize the materials in the production of asphalt mastics. This review examines the performance of mining waste-modified asphalt binder–mastic to create an idea of what tailings might be used for in subsequent studies. This review contributes to knowledge by consolidating research efforts …

Arousal As A Universal Embedding For Spatiotemporal Brain Dynamics, Ryan V Raut, Zachary P Rosenthal, Xiaodan Wang, Hanyang Miao, Zhanqi Zhang, Jin-Moo Lee, Marcus E Raichle, Adam Q Bauer, Steven L Brunton, Bingni W Brunton, J Nathan Kutz

2020-Current year OA Pubs

Neural activity in awake organisms shows widespread, spatiotemporally diverse correlations with behavioural and physiological measurements

Management Of The Patent Ductus Arteriosus Among Infants Born At 23 To 32 Weeks' Gestation Between 2011 To 2022: A Report From In The Children's Hospitals Neonatal Consortium, Mark F Weems, Molly K Ball, Isabella Zaniletti, Sharifa Habib, Shannon Hamrick, Theresa R Grover, Sarah Keene, Karna Murthy, Michael Padula, Ranjit Philip, Rakesh Rao, Shawn Sen, Philip T Levy, Sharada H Gowda, Chnc Cardiac Focus Group

2020-Current year OA Pubs

OBJECTIVE: This study reports on patent ductus arteriosus (PDA) therapy trends across the Children's Hospital Neonatal Consortium.

STUDY DESIGN: We performed a 12-year (2011-2022) retrospective study of premature infants (<  33 weeks) with a PDA. We utilized descriptive statistics to compare demographic, inpatient, and discharge characteristics in 3-year epochs.

RESULT: From 54,813 infants, 19,843 (36%) had a diagnosis of PDA. Use of pharmacotherapy increased 44% (relative) over time, mostly with increased acetaminophen use. There was a 12.7-fold increase in exposure to multiple PDA medications over the study period. While the rate of definitive closure did not change, use of transcatheter PDA closure increased from 0 to 20.3% and surgical ligation decreased from 25.1% to 3.6%.

CONCLUSION: There has been …

Sarm1 Inhibition Maintains Axonal Integrity After Rat Sciatic Nerve Transection And Repair, Ryan Sachar, Tony Y Lee, Aaron Diantonio, Christopher J Dy, Jason Wever, Jeff Milbrandt, David M Brogan

2020-Current year OA Pubs

PURPOSE: Sterile alpha and TlR motif containing-1 (SARM1) protein has been demonstrated to play a critical role in the initiation of Wallerian degeneration after nerve injury. The goal of this study was to assess whether blockade of SARM1 activity inhibits Wallerian degeneration following nerve transection, potentially promoting more rapid recovery of axonal function.

METHODS: An adeno-associated virus plasmid encoded with a dominant-negative SARM1 protein fused with green fluorescent protein to impair SARM1 function, was injected into 24 juvenile rats to create a SARM1 dominant-negative (SARM1-DN) phenotype. Twenty-four control rats were injected with a control plasmid expressing only green fluorescent protein. …

Comparing Effectiveness And Safety Of Left Atrial Appendage Closure Devices: A Network Meta-Analysis Of Randomized Controlled Trials, John W Davis, Steven L Mai, Wissam Harmouch, Jenna Reisler, Micaela Mackay, Elizabeth Davis, Pavel Osmancik, Michael W Rich

2020-Current year OA Pubs

INTRODUCTION: Atrial fibrillation-related stroke is a leading cause of morbidity and mortality. The comparative effectiveness and safety of left atrial appendage closure (LAAC) devices, compared with one another and with anticoagulation, is unclear.

METHODS: We conducted a systematic review and network meta-analysis (NMA) of all clinical trials comparing the Watchman and Amplatzer Amulet LAAC devices with each other or with warfarin or direct oral anticoagulants (DOACs). The primary comparison was between LAAC devices with secondary comparisons to anticoagulation. The primary effectiveness outcomes were any stroke and all-cause death. Safety outcomes included any thromboembolism, device embolization, and pericardial effusion.

RESULTS: There …

When A Folder Is Not A Folder: Investigating Complex Composite Content, Tyler Thorsted

Faculty Publications

Generally file formats on modern systems are single byte streams, and there are many tools available to help identify and determine what software is needed to make use of the format. When dealing with formats born on Macintosh systems, a single byte stream is often not all that is needed to make use of the formats. On older Macintosh systems a Type/Creator code and a resource fork are often needed, and on more modern systems there are other challenges that need to be addressed. This paper explores some popular formats and tools that are needed to properly assess and capture …

Hiv Pre-Exposure Prophylaxis Does Not Increase Gonorrhea And Chlamydia Incidence In Young Black And Hispanic Men Who Have Sex With Men: An Observational Cohort Study, Octavio C Mesner, Rishabh Jain, Aditi Ramakrishnan, Derrick D Matthews, Jeremy T Goldbach

2020-Current year OA Pubs

BACKGROUND: HIV pre-exposure prophylaxis (PrEP) use has been linked with increases in sexually transmitted infection (STI) incidence. Despite efforts to expand PrEP uptake among young Black and Hispanic men who have sex with men (YBHMSM), little research has been done to understand the impact of PrEP on STI incidence within these communities. We examine the effect of PrEP use on gonorrhea and chlamydia (NG/CT) incidence, condom use, and external STI testing (ie, outside of study visits).

METHODS: In a longitudinal cohort of HIV-negative YBHMSM (ages 16-24 years), we modeled the effect of PrEP use on study-external STI testing and number …

Generation Expansion Planning: Transitioning Toward Decarbonization With A Focus On Reliability And Dunkelflaute, Taraneh Ghanbarzadeh, Daryoush Habibi, S. M.Muslem Uddin, Asma Aziz

Research outputs 2022 to 2026

Modern power systems increasingly rely on variable renewable energy sources, supported by energy storage systems and gas power plants, to meet decarbonization targets. However, the high penetration of renewables introduces significant uncertainty due to their weather-dependent nature, posing challenges to system reliability. This paper proposes a probabilistic, multi-level generation expansion planning framework that integrates reliability assessments, with a particular emphasis on the role of energy storage systems. A novel probabilistic approach is also introduced to model the Dunkelflaute phenomenon and evaluate its impact on system reliability. Additionally, the study explores the influence of regulatory mechanisms — referred to as embedded …

Influence Of Organic Matter And Mineral Composition On Carbonate Source Rock Wettability: Implications For Co2 Geostorage, Muhammad Usman, Nurudeen Yekeen, Muhammad Ali, Mujahid Ali, Alireza Keshavarz, Stefan Iglauer, Volker Vahrenkamp

Research outputs 2022 to 2026

Wettability is critical in determining carbon dioxide (CO2) behavior during geological sequestration in unconventional reservoirs. Unconventional reservoirs are compositionally heterogeneous, affecting CO2 plume migration, containment security, and storage capacity during geological sequestration. Previous studies on CO2 storage in unconventional reservoirs have primarily attributed to changes in organic matter content; however, this study examines how variations in the mineralogical and organic matter content combined affect wettability in CO2/brine systems under subsurface conditions. Three samples with varied mineralogy and TOC content were selected from a well drilled in Jordan source rocks—an immature analog of marine-derived, carbonate-dominated, Type IIS source rocks. Samples were …