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Supreme Court Ruling Lets Trump Misgender Trans People On Passports While Challenge Is Pending, Arthur S. Leonard Nov 2025

Supreme Court Ruling Lets Trump Misgender Trans People On Passports While Challenge Is Pending, Arthur S. Leonard

Other Publications

No abstract provided.


Tiktok, Inc. V. Dist. Ct. [State Of Nevada], 141 Nev. Adv. Op. 51 (Nov. 06, 2025) (En Banc), Erika Loveland Nov 2025

Tiktok, Inc. V. Dist. Ct. [State Of Nevada], 141 Nev. Adv. Op. 51 (Nov. 06, 2025) (En Banc), Erika Loveland

Nevada Supreme Court Summaries

Online platforms establish specific jurisdiction when they collect and sell Nevada users' data. The CDA § 230 and 1st Amendment do not bar claims for design flaws or safety misrepresentations at the pleading stage.


Spartan Daily, November 6, 2025, San Jose State University, School Of Journalism And Mass Communications Nov 2025

Spartan Daily, November 6, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 33


Bond Trustee's Objection To Confirmation Nov 2025

Bond Trustee's Objection To Confirmation

Catholic Dioceses in Bankruptcy

No abstract provided.


Americans' Top Concerns Reflect Both Common Ground And Partisan Splits: Economy Unites, But Policy And Politics Divide, Hwayong Shin Nov 2025

Americans' Top Concerns Reflect Both Common Ground And Partisan Splits: Economy Unites, But Policy And Politics Divide, Hwayong Shin

Weidenbaum Center Survey (WCS) Reports

Over the past two years, Americans have lived through several political shocks—both at home and abroad. In 2023, the removal of House Speaker Kevin McCarthy, the Supreme Court’s reversal on affirmative action, the outbreak of the Israel–Hamas war, and Donald Trump’s multiple indictments shook the political landscape. In 2024, Americans faced a series of events surrounding the presidential election—Trump’s conviction on felony charges, the Supreme Court’s subsequent ruling granting him presidential immunity, Joe Biden’s faltering debate performance that led to his withdrawal and Kamala Harris’s nomination, and Trump’s return to the White House. Since the new administration took office in …


The Grizzly, November 6, 2025, Renee Washart, Adam Denn, Alex Zelaya, Sidney Belleroche, Hanna Moghanaki, Erin Ewing Nov 2025

The Grizzly, November 6, 2025, Renee Washart, Adam Denn, Alex Zelaya, Sidney Belleroche, Hanna Moghanaki, Erin Ewing

Ursinus College Grizzly Newspaper, 1978 to Present

UC Hall of Famer Talks Basketball Development • HoCo NoMo? This Year's Lack of a Homecoming Court • Course Registration for Spring 2026 • Community's Shared Love for Music Brings New Life to Wind Ensemble • Finding My Way with Nobel Peace Prize Laureate Malala Yousafzai • APEX at Ursinus: Unfair, and to Whom? • Where Legacies Live On: The Dave Matey Linebacker Lounge • Bears' Basketball Prepares for Battle


Optimising Adherence To Inpatient Rehabilitation Trial Protocols: A Mixed-Methods Systematic Review, Angie Logan, Jonathan Marsden, Jennifer Freeman, Emma Cork, Bridie Kent Nov 2025

Optimising Adherence To Inpatient Rehabilitation Trial Protocols: A Mixed-Methods Systematic Review, Angie Logan, Jonathan Marsden, Jennifer Freeman, Emma Cork, Bridie Kent

School of Health Professions

Background:The results of rehabilitation clinical trials can be negatively affected by adherence to trial protocols. Adherence is multi-factorial, but studies often look at adherence factors separately. Therefore, a systematic review to appraise and synthesise the evidence is warranted to determine the barriers, facilitators and predictors associated with adherence to inpatient rehabilitation trial protocols, whether and how factors interact with one another, and how adherence to rehabilitation protocols can be optimised.Methods:A mixed-methods systematic review was conducted and reported in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Databases searched were PubMed (Ovid), EMBASE (Ovid), MEDLINE (Ovid), CINAHL (Ovid), …


Mixed Chamber Ensembles Nov 2025

Mixed Chamber Ensembles

Bailey School of Music Concert Programs

Mixed Chamber Ensembles


Investigating Whether Giving Or Receiving Support Impacts Caregivers Who Were Maltreated Or Not Maltreated Differently, Tara D. Matta-Singh Nov 2025

Investigating Whether Giving Or Receiving Support Impacts Caregivers Who Were Maltreated Or Not Maltreated Differently, Tara D. Matta-Singh

USF Tampa Graduate Theses and Dissertations

Caregivers can experience higher levels of stress, anxiety and depression compared to non-caregivers. However, a growing body of literature is beginning to show that while caregiving may be stressful, there may also be benefits to the caregiver, such as feeling closer to the care recipient, a sense of purpose or personal growth. Further, research now demonstrates that giving support to others can be more beneficial than receiving support from others in terms of mental health and even mortality. While these are important advances in the literature, understanding the impacts of giving and receiving support on individuals who were maltreated by …


Safe Spaces And Free Speech On Campus: A Guided Tour Of Campus Contexts, Bryan R. Warnick, Jaime Herman, Kyle M. Williams Nov 2025

Safe Spaces And Free Speech On Campus: A Guided Tour Of Campus Contexts, Bryan R. Warnick, Jaime Herman, Kyle M. Williams

Interdisciplinary Faculty Scholarship

Contemporary events on university campuses have spotlighted the perceived conflict between free speech and safe spaces. While both values are widely acknowledged as essential, reconciling them in practice remains difficult. In this article, we argue that universities should not be viewed as singular entities but as a constellation of distinct spaces, each with its own normative context. The appropriate balance between safety and speech depends on the specific functions and values of each space. We first survey philosophical literature on campus speech and safety, noting the often-implicit acknowledgment of spatial diversity. Next, we introduce guiding questions to assist in evaluating …


The George-Anne Daily, Georgia Southern University Nov 2025

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


A Collaborative Approach To Marine Species Tracking: Insights From The Fish Intel Acoustic Telemetry Network, Alice E. Hall, Tom Stamp, Peter Davies, Mathieu Woillez, Martial Laurans, Marine Gonse, Lydie I.E. Couturier, Olivier Blanpain, Katia Frangoudes, Emmanuelle Quillérou, Eider Graner, Jan Reubens, Carlotta Muñiz, Lucy A. Hawkes, Matthew J. Witt, Thomas W. Horton, Tom Hooper, Ricky Pender, Erwin Quemeneur, Mewen Abjean, Xavier Tetard, Pascal Provost, Silvana Birchenough, Jean Luc Solandt, Colin Trundle, Amy Y. Cartwright, Sian Rees, Ronan Conlon, Shion E.A. Reynell, Ben Ciotti Nov 2025

A Collaborative Approach To Marine Species Tracking: Insights From The Fish Intel Acoustic Telemetry Network, Alice E. Hall, Tom Stamp, Peter Davies, Mathieu Woillez, Martial Laurans, Marine Gonse, Lydie I.E. Couturier, Olivier Blanpain, Katia Frangoudes, Emmanuelle Quillérou, Eider Graner, Jan Reubens, Carlotta Muñiz, Lucy A. Hawkes, Matthew J. Witt, Thomas W. Horton, Tom Hooper, Ricky Pender, Erwin Quemeneur, Mewen Abjean, Xavier Tetard, Pascal Provost, Silvana Birchenough, Jean Luc Solandt, Colin Trundle, Amy Y. Cartwright, Sian Rees, Ronan Conlon, Shion E.A. Reynell, Ben Ciotti

School of Biological and Marine Sciences

Acoustic telemetry offers valuable insights into species' spatial and temporal movement patterns, helping to understand habitat use, behaviour and migration timings. The Fish Intel Network established a collaborative cross-English Channel acoustic telemetry network to track multiple species over small and large spatial scales. This network was designed in close alliance with local fishers to incorporate essential local ecological knowledge of target species and habitats, gathered through interviews and workshops. To date, 254 acoustic receivers have been deployed, and 874 animals have been tagged across the Channel. Six species were tracked for this study: European bass (Dicentrarchus labrax), pollack (Pollachius pollachius), …


Eqr-228 W. 71st Llc V. Ford Nov 2025

Eqr-228 W. 71st Llc V. Ford

All Decisions

In this holdover proceeding alleging nuisance, the tenant moved for summary judgment, asserting the landlord failed to state a cause of action by not marking the specific good cause ground on the required GCEL notice, despite acknowledging the premises was subject to GCEL. The landlord argued GCEL applied only to non-renewal cases, not to terminations based on conduct. The court disagreed, holding that GCEL applies to all tenants in covered housing accommodations irrespective of lease expiration or tenancy type. Since the landlord failed to specify the applicable good cause basis in the GCEL notice, the tenant's motion for summary judgment …


Middle School Counselors' Perceptions Of Meeting Career Counseling Needs Of Middle School Students, Mario Oscar Garcia Nov 2025

Middle School Counselors' Perceptions Of Meeting Career Counseling Needs Of Middle School Students, Mario Oscar Garcia

USF Tampa Graduate Theses and Dissertations

This dissertation examined middle school counselors' perceptions of their effectiveness in delivering career counseling to students. Middle school is a pivotal time for career exploration and planning, yet disparities in guidance persist, particularly for students not on a traditional college pathway. Guided by the American School Counselor Association (ASCA) National Model, this study employed a survey method. An online survey developed by the researcher assessed counselors' time allocation across academic, career, social-emotional, and duties unrelated to their essential school counseling roles. Additionally, the survey inquired about counselors’ perceived effectiveness in meeting the career needs of diverse student populations (advanced academic, …


Geographic Patterns Of Educational Achievement: A Methodological Case Study Of Regression Modeling Approaches, Leokadia Lipien Nov 2025

Geographic Patterns Of Educational Achievement: A Methodological Case Study Of Regression Modeling Approaches, Leokadia Lipien

USF Tampa Graduate Theses and Dissertations

This methodological case study introduces a novel approach to investigate the impact of student, teacher, and geographic factors on the academic achievement of virtual school students in Florida. Traditional linear regression models, and even multilevel models, often overlook spatial dependencies, which can lead to biased estimates and incomplete inferences. This research addresses this limitation by comparing a cross-classified multilevel model (CCMM) with a novel cross-classified spatial model (CCSM) that incorporates coefficients from geographically weighted regression (GWR). Utilizing secondary data from a statewide virtual school, including student demographics, teacher characteristics, and standardized test scores, along with U.S. Census Bureau data, the …


Perpetration-Induced Traumatic Stress And Moral Injury In Adult Male Incarcerated Individuals, Cyrelah Jeanee Raynor Nov 2025

Perpetration-Induced Traumatic Stress And Moral Injury In Adult Male Incarcerated Individuals, Cyrelah Jeanee Raynor

Walden Dissertations and Doctoral Studies

Underutilizing trauma-informed approaches in correctional rehabilitation has had detrimental consequences, particularly for gang-involved populations. Theories of personality, responsivity, and stress suggest that gang-affiliated individuals, shaped by coercive environments, may develop psychological reactions such as fear, guilt, and moral shame that contribute to posttraumatic stress disorder (PTSD) and moral injury (MI). This study examined whether gang role, psychopathy, and perpetration predicted PTSD and MI among 70 incarcerated adult males. Participants completed the Moral Injury Outcome Scale (MIOS), the PTSD Checklist for DSM-5 (PCL-5), and the Levenson Self-Report Psychopathy Scale (LSRP). Two hierarchical regressions were conducted. In the PTSD model, only education …


Distinct Tumor-Associated Macrophage Signatures Shape The Immune Microenvironment And Patient Prognosis In Renal Cell Carcinoma, Youngsoo Han, Aidan Shen, Cheng-Chi Chao, Lucas Yeung, Aliesha Garrett, Jianming Zeng, Satoru Kawakita, Jesse Wang, Zhaohui Wang, Alireza Hassani, Xiling Shen, Chongming Jiang Nov 2025

Distinct Tumor-Associated Macrophage Signatures Shape The Immune Microenvironment And Patient Prognosis In Renal Cell Carcinoma, Youngsoo Han, Aidan Shen, Cheng-Chi Chao, Lucas Yeung, Aliesha Garrett, Jianming Zeng, Satoru Kawakita, Jesse Wang, Zhaohui Wang, Alireza Hassani, Xiling Shen, Chongming Jiang

Faculty, Staff and Student Publications

Renal cell carcinoma (RCC) accounts for 90% of adult renal cancer cases and is characterized by significant heterogeneity within its tumor microenvironment. This study tests the hypothesis that tumor-associated macrophages (TAMs) influence RCC progression and patient response to treatment by investigating the prognostic implications of TAM signatures. Utilizing independent single-cell RNA sequencing data from RCC patients, we developed eight distinct TAM signatures reflective of TAM presence. A LASSO Cox regression model was constructed to predict survival outcomes, evaluated using the TCGA dataset, and validated across independent RCC cohorts. Model performance was assessed through Kaplan-Meier survival plots, receiver operating characteristic (ROC) …


Menin Inhibitor Ds-1594b Drives Differentiation And Induces Synergistic Lethality In Combination With Venetoclax In Acute Myeloid Leukemia Cells With Rearranged Mixed-Lineage Leukemia And Mutated Nucleophosmin-1, Valerio Ciaurro, Vassilena Sharlandjieva, Anna Skwarska, Catherine Chahrour, Natalia Baran, Zhihong Zeng, Cassandra Ramage, Naval Daver, Bing Z Carter, Sovira Chaundhry, Palaniraja Thandapani, Maria Paola Martelli, Thomas A Milne, Marina Konopleva Nov 2025

Menin Inhibitor Ds-1594b Drives Differentiation And Induces Synergistic Lethality In Combination With Venetoclax In Acute Myeloid Leukemia Cells With Rearranged Mixed-Lineage Leukemia And Mutated Nucleophosmin-1, Valerio Ciaurro, Vassilena Sharlandjieva, Anna Skwarska, Catherine Chahrour, Natalia Baran, Zhihong Zeng, Cassandra Ramage, Naval Daver, Bing Z Carter, Sovira Chaundhry, Palaniraja Thandapani, Maria Paola Martelli, Thomas A Milne, Marina Konopleva

Faculty, Staff and Student Publications

Mixed-lineage leukemia (MLL) rearrangements and Nucleophosmin-1 (NPM1) mutations are associated with acute leukemias whose pathogenesis is critically influenced by protein-protein interactions between menin and MLL. We hypothesized that targeting the menin-MLL interaction using DS-1594b and blocking the antiapoptotic BCL-2 protein using venetoclax may promote differentiation and enhance eradication of MLL-rearranged and NPM1-mutated leukemias models. We treated acute myeloid leukemia (AML) cell lines with MLL rearrangements, NPM1 mutations, other leukemias and primary samples from AML patients with venetoclax alone, DS- 1594b alone, and their combination. We measured proliferation, viability, apoptosis, and differentiation using a variety of cellular assays, Western blotting, and …


Mutational Landscape And Clinical Impact Of Spen Mutations In Patients With Chronic Lymphocytic Leukemia, Priyatharsini Nirmalanantham, Andrés E Quesada, Anindita Ghosh, Pei Lin, Chi Y Ok, Richard K Yang, Hong Fang, Sofia Garces, Rashmi Kanagal-Shamanna, Sanam Loghavi, Mark J Routbort, Cameron Cheng Yin, Wang Wei, Sarah Pasyar, Roland Bassett, Siba El Hussein, Nitin Jain, Jan Burger, William G Wierda, Sa Wang, Carlos Bueso-Ramos, Keyur P Patel, Leonard Jeffrey Medeiros, Fatima Zahra Jelloul Nov 2025

Mutational Landscape And Clinical Impact Of Spen Mutations In Patients With Chronic Lymphocytic Leukemia, Priyatharsini Nirmalanantham, Andrés E Quesada, Anindita Ghosh, Pei Lin, Chi Y Ok, Richard K Yang, Hong Fang, Sofia Garces, Rashmi Kanagal-Shamanna, Sanam Loghavi, Mark J Routbort, Cameron Cheng Yin, Wang Wei, Sarah Pasyar, Roland Bassett, Siba El Hussein, Nitin Jain, Jan Burger, William G Wierda, Sa Wang, Carlos Bueso-Ramos, Keyur P Patel, Leonard Jeffrey Medeiros, Fatima Zahra Jelloul

Faculty, Staff and Student Publications

Background/objectives: NOTCH1 is frequently mutated in chronic lymphocytic leukemia (CLL) and is a marker of poor prognosis. In addition to NOTCH1, mutations in the NOTCH1 regulatory pathway including SPEN have been described in a limited number of CLL cases and others have suggested that these mutations are also associated with adverse patient outcomes Methods: In this study, 1617 CLL cases were assessed using targeted sequencing and a 29-gene panel and the results were correlated with prognosis.

Results: SPEN mutations were detected in 48 (2.9%) CLL patients: 92.4% were deleterious (frameshift or truncating nonsense mutations) and the remaining (7.6%) were …


Treatment Planning For Patients With Acoustic Neuroma., Andrew J. Fishman, Oskar Rosiak, Arnaldo Rivera, Michael D. Puricelli, Nenad Zivkovic, Jozef Mierzwinski, Bojan Markovic, Natalija Milisavlevic, Radosław Rola, Marcin Szymanski Nov 2025

Treatment Planning For Patients With Acoustic Neuroma., Andrew J. Fishman, Oskar Rosiak, Arnaldo Rivera, Michael D. Puricelli, Nenad Zivkovic, Jozef Mierzwinski, Bojan Markovic, Natalija Milisavlevic, Radosław Rola, Marcin Szymanski

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Acoustic neuroma (AN) is a benign tumor of the vestibulocochlear nerve, with increasing detection due to improved imaging. Treatment decisions are complex, requiring an individualized approach based on tumor size, location, growth rate, and patient-specific factors such as hearing and vestibular function.

RESULTS: Treatment options include observation, microsurgery, and stereotactic radiosurgery. Hearing preservation is prioritized in select cases using middle cranial fossa or retrosigmoid approaches, while translabyrinthine surgery is preferred for larger tumors or disabling dizziness. Stereotactic radiosurgery offers a non-invasive alternative but has variable long-term hearing outcomes and potential tumor regrowth. Vestibular rehabilitation is essential post-treatment, particularly after …


Aberrant Expression Of A Disintegrin And Metalloproteinase With Thrombospondin Motifs 13 (Adamts13) In Pancreatic Cancer Leads To Dichotomic Functions, Stephanie Allmang, Hagen R. Witzel, Anne Hausen, Simone Marquard, Christoph Eckert, Nicole Marnet, Nina Hörner, Philipp Mayer, Stefan Heinrich, Hien Dang, Wilfried Roth, Matthias M. Gaida Nov 2025

Aberrant Expression Of A Disintegrin And Metalloproteinase With Thrombospondin Motifs 13 (Adamts13) In Pancreatic Cancer Leads To Dichotomic Functions, Stephanie Allmang, Hagen R. Witzel, Anne Hausen, Simone Marquard, Christoph Eckert, Nicole Marnet, Nina Hörner, Philipp Mayer, Stefan Heinrich, Hien Dang, Wilfried Roth, Matthias M. Gaida

Department of Surgery Faculty Papers

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers characterized by highly invasive growth into the surrounding peripancreatic fat tissue, where tumor cells can directly interact with adipocytes. Due to poor response to the currently available (radio)chemotherapies, there is an urgent need for advanced therapy concepts. The present study shows that ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin motifs 13), a key factor in blood coagulation, is significantly overexpressed in human PDAC. Immunohistochemical analysis revealed that ADAMTS13 expression is associated with prolonged survival and negatively correlated with vascular density. In vitro and in vivo experiments demonstrate its partial …


Increase Your Impact And Visibility With Scholarworks@Utep, Alyssa Pope, Angela Lucero, Maria Teresa Torres Nov 2025

Increase Your Impact And Visibility With Scholarworks@Utep, Alyssa Pope, Angela Lucero, Maria Teresa Torres

HIIT 2025

Slides presented at the 2025 HIIT Conference's "Breakfast with the Library".

Join the UTEP Library for an informative session on ScholarWorks@UTEP, our institutional digital repository. You'll learn how ScholarWorks@UTEP increases the visibility and impact of your research, and get hands-on guidance uploading your scholarly works—including articles, conference papers, datasets, creative materials, and more.


Use Of An Expert Panel For Symptomatic Patients With Grade I Degenerative Lumbar Spondylolisthesis: A Randomized Clinical Trial, Zoher Ghogawala, Tasneem Rizvi, Zhibang Lin, Adam Kanter, Praveen Mummaneni, Erica Bisson, Todd Albert, Daniel Resnick, Michael Wang, Steven Glassman, David Polly, Mohamad Bydon, Subu Magge, Luis Tumialan, Michael Fehlings, Michael Steinmetz, Robert Whitmore, Vedantam Rajshekhar, James Harrop, Roger Härtl, Elnasri Ahmed, Dom Coric, Paul Mccormick, Richard Assaker, Abdul Msaddi, Langston Holly, Yoshiharu Kawaguchi, Asdrubal Falavigna, Fred Barker, Edward Benzel Nov 2025

Use Of An Expert Panel For Symptomatic Patients With Grade I Degenerative Lumbar Spondylolisthesis: A Randomized Clinical Trial, Zoher Ghogawala, Tasneem Rizvi, Zhibang Lin, Adam Kanter, Praveen Mummaneni, Erica Bisson, Todd Albert, Daniel Resnick, Michael Wang, Steven Glassman, David Polly, Mohamad Bydon, Subu Magge, Luis Tumialan, Michael Fehlings, Michael Steinmetz, Robert Whitmore, Vedantam Rajshekhar, James Harrop, Roger Härtl, Elnasri Ahmed, Dom Coric, Paul Mccormick, Richard Assaker, Abdul Msaddi, Langston Holly, Yoshiharu Kawaguchi, Asdrubal Falavigna, Fred Barker, Edward Benzel

Department of Neurosurgery Faculty Papers

BACKGROUND AND OBJECTIVES: The appropriate utilization of lumbar fusion when performing laminectomy for lumbar spondylolisthesis is uncertain. The objective was to determine whether the use of a surgical expert review panel recommending fusion might improve patient selection, possibly reducing surgical failures.

METHODS: Randomized clinical trial of patients with symptomatic degenerative lumbar stenosis with spondylolisthesis enrolled from 14 North American hospitals was conducted with patients randomized to receive an expert panel review of their case or not. Spinal expert review consisted of 10 to 15 surgeons' review of patient images and clinical data with voting on the appropriateness of fusion. Primary …


Presentation Of Final Results 11-6-2025, Chad Pritchard Nov 2025

Presentation Of Final Results 11-6-2025, Chad Pritchard

EWU PFAS Research Collection

A 50 minute presentation of the final results from the 2023-2025 PFAS Fate and Transport Study of the West Plains conducted by Dr. Chad Pritchard, Department of Geosciences, Eastern Washington University.

A recording of this lecture is avaliable at:

https://www.youtube.com/watch?v=5brQD_UulRw


Influenza Vaccine Effectiveness Against Medically Attended Outpatients Illness, United States, 2023-2024 Season, Jessie R Chung, Stacey L House, Tara Curley, Et Al. Nov 2025

Influenza Vaccine Effectiveness Against Medically Attended Outpatients Illness, United States, 2023-2024 Season, Jessie R Chung, Stacey L House, Tara Curley, Et Al.

2020-Current year OA Pubs

BACKGROUND: The 2023-2024 US influenza season was characterized by a predominance of A(H1N1)pdm09 virus circulation with cocirculation of A(H3N2) and B/Victoria viruses. We estimated vaccine effectiveness (VE) in the United States against mild-to-moderate medically attended influenza illness in the 2023-2024 season.

METHODS: We enrolled outpatients aged ≥8 months with acute respiratory illness in 7 states. Respiratory specimens were tested for influenza type/subtype by reverse-transcriptase polymerase chain reaction. Influenza VE was estimated with a test-negative design comparing odds of testing positive for influenza among vaccinated versus unvaccinated participants. We estimated VE by virus subtype/lineage and A(H1N1)pdm09 genetic subclades.

RESULTS: Among 6629 …


Survival Analysis Of Breast Cancer Patients In Texas Using Classical And Machine Learning Methods, Sidketa Fofana, Tamer Oraby, Salique H. Shaham, Everardo Cobos, Manish K. Tripathi Nov 2025

Survival Analysis Of Breast Cancer Patients In Texas Using Classical And Machine Learning Methods, Sidketa Fofana, Tamer Oraby, Salique H. Shaham, Everardo Cobos, Manish K. Tripathi

School of Medicine Publications

Background

Breast cancer is considered one of the most common cancers in women worldwide. In this study, we used an 11-year cohort of malignant breast cancer survival data in Texas to investigate the factors that might explain why some breast cancer patients live longer than others.

Methods

We performed standard survival analyses, including generating Kaplan‒Meier survival curves, using the log-rank test, and applying Cox proportional hazards regression to identify the unique features of breast cancer patients and determine the main factors influencing long-term survival. We also conducted a Random Survival Forest analysis for classification and prediction. Finally, we used Mahalanobis …


A Socioecological Needs Assessment Of Alternative Learning Environments: Implications For Occupational And Mental Well-Being In School Settings, Glenda Hux, Sydney Rice, Lexus Brettell Wicinski, John V. Rider Nov 2025

A Socioecological Needs Assessment Of Alternative Learning Environments: Implications For Occupational And Mental Well-Being In School Settings, Glenda Hux, Sydney Rice, Lexus Brettell Wicinski, John V. Rider

Communication Disorders and Occupational Therapy Faculty Publications and Presentations

Alternative learning environments (ALEs) support students with complex behavioral, emotional, and social needs, yet only a small amount of research has examined their occupational and mental health needs using a socioecological approach. This study aimed to demonstrate the process of conducting a socioecological needs assessment in an ALE and identify needs from multiple stakeholder perspectives. A qualitative descriptive design was employed. Semi-structured interviews and focus groups were conducted with 24 stakeholders, including students, educators, counselors, administrators, and a dietitian. Data were analyzed thematically by stakeholder group. Four overarching themes emerged: This School is a Shelter, We Believe in Resilience, We …


Can Dietary Supplements Support Muscle Function And Physical Activity? A Narrative Review, Louise Brough, Gail Rees, Lylah Drummond-Clarke, Jennifer E. Mccallum, Elisabeth Taylor, Oleksii Kozhevnikov, Steven Walker Nov 2025

Can Dietary Supplements Support Muscle Function And Physical Activity? A Narrative Review, Louise Brough, Gail Rees, Lylah Drummond-Clarke, Jennifer E. Mccallum, Elisabeth Taylor, Oleksii Kozhevnikov, Steven Walker

School of Biomedical Sciences

Dietary supplementation is commonly used by athletes to gain muscle mass, enhance performance, and improve recovery. Most adults engage in insufficient physical activity. Yet healthy muscles are also critical for activities of daily living (ADLs), maintaining a good quality of life and positive ageing. There is growing interest in whether dietary supplementation is of value, particularly among subgroups such as the occasionally active, the ill and elderly, and peri- and menopausal women. By focusing on function, performance, mass and strength, ADLs, exercise-induced muscle damage and delayed onset muscle soreness, this review sought to examine muscle health through a nutritional lens. …


Updated Systematic Review Of Current Randomised Controlled Trials In Chronic Subdural Haematoma, On Be Half Of The International Collaborative Research Initiative On Chronic Subdural Haematoma (Icoric) Study Group, R Fakhry, C Yesildal, J Bartek, J Duerinck, T S R Jensen, J Soleman, C Iorio-Morin, C M F Dirven, R Dammers, E Edlmann, D C Holl Nov 2025

Updated Systematic Review Of Current Randomised Controlled Trials In Chronic Subdural Haematoma, On Be Half Of The International Collaborative Research Initiative On Chronic Subdural Haematoma (Icoric) Study Group, R Fakhry, C Yesildal, J Bartek, J Duerinck, T S R Jensen, J Soleman, C Iorio-Morin, C M F Dirven, R Dammers, E Edlmann, D C Holl

Peninsula Medical School

BACKGROUND: Chronic subdural haematoma (CSDH) is a common neurosurgical condition with an increasing incidence due to an aging population. Given the expanding research landscape, assessing the state of recent trials is essential. This systematic review updates a previous review, which included randomised controlled trials (RCTs) up to 2019, by summarizing recently published and ongoing RCTs in CSDH, highlighting key areas of investigation and identifying directions for future research. METHODS: Clinical trial registries - including the Cochrane Controlled Register of Trials, WHO ICTRP, clinicaltrials.gov, and Clinical Trials Information System - were systematically searched for RCTs on CSDH from June 1, 2019, …


The Utility Of Ultra-Deep Rna Sequencing In Mendelian Disorder Diagnostics, Sen Zhao, Jefferson C Sinson, Shenglan Li, Jill A Rosenfeld, Gladys Zapata, Kristina Macakova, Mezthly Pena, Becky Maywald, Kim C Worley, Lindsay C Burrage, Monika Weisz-Hubshman, Shamika Ketkar, William Craigen, Lisa Emrick, Undiagnosed Diseases Network, Tyson Clark, Gila Yanai Lithwick, Zohar Shipony, Christine Eng, Brendan Lee, Pengfei Liu Nov 2025

The Utility Of Ultra-Deep Rna Sequencing In Mendelian Disorder Diagnostics, Sen Zhao, Jefferson C Sinson, Shenglan Li, Jill A Rosenfeld, Gladys Zapata, Kristina Macakova, Mezthly Pena, Becky Maywald, Kim C Worley, Lindsay C Burrage, Monika Weisz-Hubshman, Shamika Ketkar, William Craigen, Lisa Emrick, Undiagnosed Diseases Network, Tyson Clark, Gila Yanai Lithwick, Zohar Shipony, Christine Eng, Brendan Lee, Pengfei Liu

Faculty, Staff and Students Publications

RNA sequencing (RNA-seq) has emerged as a powerful tool for resolving variants of uncertain significance (VUSs), particularly those affecting gene expression and splicing. However, most reference datasets and diagnostic protocols employ relatively modest sequencing depths (∼50-150 million reads), which may fail to detect low-abundance transcripts and rare splicing events critical for accurate diagnosis. We evaluated the diagnostic and translational utility of ultra-high-depth (up to ∼1 billion unique reads) RNA-seq in four clinically accessible tissues using the Ultima sequencing platform. After validating the performance of Ultima RNA-seq, we investigated how increasing sequencing depth affects gene and isoform detection, splicing variant discovery, …