Digital Commons Network^™

Fear The Feminine! Willa Cather’S O Pioneers, Edith Wharton’S The Glimpses Of The Moon, And The Rejection Of Femininity In The Canon Formation Of Realist And Naturalist Writing, Anna Connor

Honors Program Theses and Projects

No abstract provided.

Elevated Lactate In Aml Bone Marrow Contributes To Macrophage Polarization Via Gpr81 Signaling., Celia A Soto, Maggie L Lesch, Jennifer L Becker, Azmeer Sharipol, Amal Khan, Xenia L Schafer, Zhewen Li, Amanda R Streeter, Michael W Becker, Joshua C Munger, Benjamin J Frisch

Oncology Articles

Interactions between acute myeloid leukemia (AML) and the bone marrow microenvironment (BMME) are critical to leukemia progression and chemoresistance. In the solid tumor microenvironment, altered metabolite levels contribute to cancer progression. We performed a metabolomic analysis of AML patient bone marrow serum, revealing increased metabolites compared to age- and sex-matched controls. The most highly elevated metabolite in the AML BMME was lactate. Lactate signaling in solid tumors induces immunosuppressive tumor-associated macrophages and correlates with poor prognosis. This has not yet been studied in the leukemic BMME. Herein, we describe the role of lactate in the polarization of leukemia-associated macrophages (LAMs). …

Cracking The Shell: A Corpus-Based Analysis Of The Functions Of Shell Nouns In American Legal Contracts, Geoffrey T. Julian

Undergraduate Honors Theses

The forms and functions of shell nouns (SN), semantically abstract nouns that can package and characterize complex segments of discourse, have been documented in academic discourse and L2 English writing (e.g., Aktas & Cortes, 2008; Benitez-Castro & Thompson, 2015). The abstract nature of SNs lends itself to use where vague language might be favored to allow for a variety of contingencies (Benitez-Castro, 2015). Thus, SNs have also been found to be present in legal language where some of these functions are desirable (Ren et al., 2019). The present study examines the use of SNs in a corpus of 2,700 US …

Assessing Readiness For Point-Of-Care Ultrasound Implemenatation In A Neonatal Intensive Care Unit, Stacy Lynn Brunquist

Student Projects for Graduate Degrees

Point-of-care ultrasound (POCUS) is an emerging diagnostic tool in neonatal care, yet widespread use in NICUs remains limited by provider training, confidence and organizational readiness. The purpose of this evidence-based practice project was to evaluate whether a brief POCUS educational intervention improved NICU provider readiness for adoption. Using a pre/post design, NICU providers at a regional tertiary NICU in Alaska completed the POCUS Readiness and Adoption Survey (PRAS) immediately before and after a structured 45-minute POCUS orientation presentation. The PRAS measured six domains: knowledge, attitudes, change efficacy, organizational support, intent to adopt, and perceived barriers. Twelve providers completed both surveys. …

Expressing Diversity And Anxiety Among Graduate Psychology Students, Selenda Johnson

Walden Dissertations and Doctoral Studies

Gender-based distinctions between leaders create differences in leadership methods that reshape their choices and teamwork approaches. Human Resource Administrators are concerned with how the lack of organizational support for Emotional Intelligence (EI) in female leaders influences them to leave, potentially leading to increased organizational costs. Grounded in Emotional Intelligence theory, the purpose of this qualitative pragmatic study was to explore EI strategies used by healthcare administrators in the Southeastern United States to increase female leadership retention in their organizations. The participants were 6 HR administrators with at least 2 years of experience from healthcare organizations who successfully implemented EI strategies …

Empowering Digital Fluency: A Course-Based Strategy For Practical Ai Tool Integration In Higher Education, Melissa J. Brooks

Teaching Repository of AI-Infused Learning

This course was designed to introduce students to a range of AI tools while enabling hands-on experience in their practical application. Students were required to explore multiple AI tools across domains such as content generation, data visualization, video production, note-taking, and accessibility. The course culminated in a final project where students selected and applied an AI tool (or set of tools) to create a resume, a cover letter, and a presentation about themselves and how they anticipate the use of AI in their chosen Industry. Tools recommended were Jenni.AI, ChatGPT, Slide bean, Canva, Grammarly, Gamma, Synthesia.AI, and Perplexity, Otter.AI. One …

Helping Students Build Artificial Intelligence Literacy Skills By Applying Leadership Theories To Their Career Development, Anthony Edwards

Teaching Repository of AI-Infused Learning

In this article, the author describes an assignment where master’s level higher education leadership students use AI to determine how leadership theories and concepts can help them in their careers and evaluate the response.

Practicing Disciplinary Role-Play With Ai: Bioinspired Innovation Meets Business Strategy, Christine R. Rodriguez

Teaching Repository of AI-Infused Learning

Students use Blackboard’s AI Conversation tool to rehearse their team’s innovation pitch with a simulated investor. This role-play activity prepares students to confidently communicate scientific ideas in business contexts and strengthens final group presentations.

From Myths To Mastery: A Progressive Ai Literacy Course Using The Clear Framework And Authentic Problem-Solving, Laura J. Mcneill, Sierra Cantrell

Teaching Repository of AI-Infused Learning

"Digital Minds: Your AI Adventure Begins" employs a 14-week progressive scaffolding approach that transforms freshman students from passive AI consumers into critical collaborators through weekly hands-on experiments with tools like ChatGPT, Gemini, and Adobe Firefly. Each week features structured "AI Questions" that connect course concepts to students' lived experiences, combined with practical activities like creating Gemini GEMS projects that encourage students to investigate AI myths and cross-reference external sources in real-time. The course culminates in collaborative AI-human projects addressing real community problems, with ongoing peer evaluation and reflection that emphasizes critical thinking and ethical reasoning over technical outputs.

Beat Chatgpt: Cultivating Critical Ai Literacy Through Student-Created Problems, Sybil Prince Nelson

Teaching Repository of AI-Infused Learning

Beat ChatGPT is a gamified assignment that positions AI as both a rival and a resource to foster critical AI literacy. Students either design statistics problems that ChatGPT is likely to answer incorrectly or critique flawed AI-generated solutions, then provide accurate responses and reflections. This strategy not only deepens disciplinary understanding but also equips students to engage with AI tools thoughtfully, ethically, and creatively.

Impact Of Novel Rheumatic Heart Disease Education On Rwandan Nurses' Knowledge And Skills, Julie Carragher

Biennial Convention (CONV)

Untreated group A streptococcus pharyngitis, along with the resulting post-infection sequelae of acute rheumatic fever (ARF) and rheumatic heart disease (RHD) of young susceptible individuals occurs in lower income countries, including Rwanda. This is largely due to limited access health care and inadequate knowledge about the detection and treatment of the infection. Approximately 33 million people worldwide live with RHD. In Rwanda, the prevalence of RHD is estimated at 6.8 per 1000 school children. With only nine cardiologists serving a population of nearly fourteen million, there is a significant gap in accessible RHD care across the country. In Rwanda, nurses, …

Analytical Assessment Of Pedestrian Crashes On Low-Speed Corridors, Therezia Matongo, Deo Chimba

Civil and Architectural Engineering Faculty Research

This study presents a comprehensive statewide analysis of pedestrian-involved crashes recorded in Tennessee between 2002 and 2025. We evaluated the influence of roadway, traffic, environmental, and socioeconomic factors on pedestrian crash frequency and severity with substantial components focused on lighting impacts including dark and nighttime. A multi-method analytical framework was implemented, combining descriptive statistics, non-parametric tests, regression analysis, and advanced machine learning techniques including the Adaptive Neuro-Fuzzy Inference System (ANFIS) and the gradient boosting model (XGBoost). Results indicated that dark and nighttime conditions accounted for a disproportionate share of severe crashes—fatal and serious injuries under dark conditions reached over 40%, …

Implementing Dataops: A Scalable Framework For Modern Data Warehousing, Dmytro Valiaiev

Theses and Dissertations

DataOps has been coined as a novel term that emerged as a synthesis of data management practices with software engineering concepts, such as DevOps and Agile, with the goal of improving data quality and governance in enterprises. The proliferation of scratch table use and transformation tools, such as dbt, has led to an exponential increase in the number of data models, which complicates standardization efforts and increases maintenance overhead. Although the market is saturated with various flavors of text-to-SQL engines that promote increased productivity and self-service use in organizations, there are limited tools available to optimize individual queries, enforce consistency, …

December 9, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

2025-11-18 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

Cv: Margaret Lupo (Radiography), Margaret Lupo

Health Sciences Department Curricula Vitae

No abstract provided.

Disrupting Cell Death: Ferroptosis And Pyroptosis Inhibition In Hepatic Ischemia-Reperfusion Injury Via Modulation Of Gpx4 And Cgas Pathways By Deferoxamine And Octreotide,, Rasha A. Tawfiq, Yasmeen Attia, Hameis M. Sleem, Mai Ghoneim Dr.

Pharmacy

Hepatic ischemia-reperfusion injury (HIRI) is a significant complication of liver transplantation, often precipitating postoperative liver dysfunction/failure. Given the rising global prevalence of end-stage liver disease, which necessitates liver transplantation, protecting against HIRI is crucial. Here, we investigated the effects of octreotide (OCT), a pyroptosis inhibitor, and deferoxamine (DEF), a ferroptosis suppressor, individually and combined in the HIRI model. Their impact on cyclic GMP-AMP synthase/stimulator-of-interferon (cGAS/STING) genes and glutathione peroxidase 4 (GPX4) activity was explored. Male rats (n = 4–5) were subjected to 30 min ischemia followed by 3 h reperfusion and treated with OCT (75 μg/kg; 30 μg/kg, i.p. & …

Healthcare Leaders’ Effective Strategies For Shaping Organizational Culture, Samuel H. Zoker

Walden Dissertations and Doctoral Studies

Some leaders in healthcare organizations lack effective leadership strategies and practices to influence and shape organizational culture, leading to inconsistent cultural values and behaviors that undermine organizational effectiveness and employee engagement. Grounded in transformational leadership theory, the purpose of this qualitative pragmatic inquiry was to explore strategies healthcare leaders use to shape organizational culture and strengthen employee engagement. Using purposive sampling, seven healthcare leaders with three or more years of experience were recruited from a medical institution. Data were collected through semistructured interviews using a protocol refined with the IPR method. Using reflective thematic analysis, five themes emerged: (a) employee-engagement …

Examining Emotional Intelligence Strategies Of Human Resource Administrators For Women’S Leadership In Healthcare, Selenda Johnson

Walden Dissertations and Doctoral Studies

Gender-based distinctions between leaders create differences in leadership methods that reshape their choices and teamwork approaches. Human Resource Administrators are concerned with how the lack of organizational support for Emotional Intelligence (EI) in female leaders influences them to leave, potentially leading to increased organizational costs. Grounded in Emotional Intelligence theory, the purpose of this qualitative pragmatic study was to explore EI strategies used by healthcare administrators in the Southeastern United States to increase female leadership retention in their organizations. The participants were 6 HR administrators with at least 2 years of experience from healthcare organizations who successfully implemented EI strategies …

From The Margins To The Center: The Transformative Promise Of Philosophy For Children, Maughn Rollins Gregory, Megan Jane Laverty, Joe Oyler

Department of Educational Foundations Scholarship and Creative Works

What began as an innovative idea in the late 1960s—the recognition that even very young children are philosophically disposed—is no longer considered novel. While philosophy for children has transitioned from a fledgling initiative to a worldwide movement, it remains on the margins of education. In this article, we look back at key initiatives that have advanced its growth before looking ahead to what can move philosophy for children to the center of education. We consider the introduction and development of materials that invite children into philosophical spaces, the community of philosophical inquiry as a model of teachers' and children's philosophical …

Ai And Racism: 6 Reasons Black People Need Digital Literacy, Brianna A. Baker

Publications and Research

Key Points

• AI often reflects racial bias in its training data, which can distort how Black people are represented.
• Psychological stress increases when digital tools misunderstand or misinterpret Black experiences.
• Digital literacy strengthens emotional wellbeing by helping users recognize and counter biased outputs.

How Does County Educational Composition Affect Mortality?, Heeyoung Lee, Tse-Chuan Yang

Population Health Research Brief Series

The gap in life expectancy between Americans with and without a bachelor's degree keeps growing. This brief summarizes findings from a study using data from the National Center for Health Statistics Multiple Cause of Death files and the American Community Survey on 3,122 U.S. counties from 2010-2022. The authors find that a county's educational makeup creates divergent mortality effects for residents. For every 1% increase in bachelor's degree holders in a county, mortality declines by 4.5% for degree holders but increases by 1.2% for those without degrees. This pattern holds across heart disease, cancer, and stroke. The findings suggest that …

Identification Of Predictive Pretreatment Biomarkers For Neoadjuvant Chemotherapy Response In Latino Invasive Breast Cancer Patients, Hedda Michelle Guevara-Nieto, Rafael Parra-Medina, Carlos A. Orozco, Sandra Diaz-Casas, Jone Garai, Jovanny Zabaleta, Liliana López-Kleine, Alba L. Combita

School of Medicine Faculty Publications

Background: Breast cancer (BC) exhibits significant heterogeneity in incidence and mortality worldwide. Neoadjuvant chemotherapy (NAC) is the standard treatment for locally advanced BC; however, its efficacy varies by subtype. This study examined the gene expression profiles associated with NAC response in Colombian women with invasive BC. Methods: RNA sequencing of pre-treatment tissues from 58 patients (29 responders and 29 non-responders) identified differentially expressed genes (DEGs) for each molecular subtype, and prognostic performance was evaluated using risk scores. Results: Functional enrichment analysis highlighted the immune system pathways in non-responders. Changes in cytokine target activity and immune cell populations were analyzed to …

Portable Skin Imaging Light-Box For Clinical Grade Skin Scans, Kayandra Lewis, Cayden Skidmore, Komi Atitsogbe Golo

Senior Design Project For Engineers

This project focuses on designing and developing a modular, portable skin-imaging light box to improve the consistency and accuracy of smartphone-based dermatological imaging. As AI-driven skin assessment tools grow in capability, a major limitation remains the variability in lighting, angle, and color fidelity in user-captured photos. To address this challenge, the team created a fold-flat, low-cost light box that attaches securely to a wide range of smartphones and provides uniform, high-CRI illumination suitable for clinical-grade analysis. Research into lighting technologies, human factors, smartphone specifications, and AI diagnostic tools guided the engineering decisions, ensuring the design aligned with real-world telemedicine and …

2025-12-09 Feedback Data From Survey, Morehead State University. Staff Congress.

Staff Congress Records

Feedback data from the Staff Congress survey submitted on December 9, 2025.

2025-12-09 Staff Survey Powerpoint, Morehead State University. Staff Congress.

Staff Congress Records

A PowerPoint on a recent survey conducted by the Staff Congress on key issues submitted on December 9, 2025,

Consensus-Based Expert Recommendations For Diagnosis And Clinical Management Of Vanishing White Matter., Romy J. Van Voorst, Daphne H. Schoenmakers, Joshua L. Bonkowsky, Adeline Vanderver, Ingeborg Krägeloh-Mann, Geneviève Bernard, Enrico Bertini, Ali Fatemi, Paulo V. Sgobbi, Nicole I. Wolf, Samuel Groeschel, Davide Tonduti, Caroline Sevin, Jennifer L. Orthmann-Murphy, Ludger Schöls, Ettore Salsano, Bernard Brais, Nicole Jaffe, Kasper W. Ter Horst, Sabine E. Hannema, Katherine G. Hayes, Jochen Meyburg, Marc Van Heerde, Anne Marie Sbrocchi, Rosalina Van Spaendonk, Isabelle Thiffault, Geesje H. Hofsteenge, Carolina Sudmeier-Broek, Corrie Timmer, Donna Skwirut, Allyson Buck, Bret Hollberg, Ron Chapleau, Hanka Dekker, Susan G. Campbell, Truus E M Abbink, Prisca S. Leferink, Marjo S. Van Der Knaap

Manuscripts, Articles, Book Chapters and Other Papers

Vanishing white matter (VWM) is a rare disorder, characterized by degeneration of CNS white matter, clinically often exacerbated by stressors such as fever and minor head trauma. VWM is caused by biallelic pathogenic variants in the EIF2B1-5 genes, causing reduced activity of eukaryotic initiation of translation factor 2B, resulting in dysregulation of the integrated stress response (ISR). New scientific insights and increased clinical trials in experimental therapies highlight the need for clinical guidelines to improve and standardize care for patients with VWM worldwide. Standardized care is important for therapy development, as it lessens clinical variability of trial participants at study …

Glycoside Hydrolase-Mediated Glucomannan Catabolism In Segatella Copri, A Target Of Microbiota-Directed Foods For Malnourished Children, Cyrus Zhou, Matthew C Hibberd, Evan M Lee, Suzanne Henrissat, Marie A Crane, Jiye Cheng, Michael J Barratt, Jeffrey I Gordon, Et Al.

2020-Current year OA Pubs

Evidence is emerging that perturbed postnatal gut microbiota development is causally related to childhood undernutrition. Clinical trials in undernourished Bangladeshi children found that a polysaccharide-rich, microbiota-directed complementary food (MDCF-2) designed to repair this perturbation produced superior ponderal and linear growth compared to a standard ready-to-use supplementary food. Subsequent analyses disclosed several candidate bioactive polysaccharides in the MDCF and their bacterial targets, notably strains of

Modeling Private Debt Using U.S. Consumer Expenditure Data, Stsiapan Dziamentsyeu

Honors Capstones

This project models private household debt among U.S. consumers using data from the Consumer Expenditure Survey (CES) between 2013 and 2023. The analysis focuses on identifying how demographic and economic characteristics, such as income, housing expenditures, education, and occupation, relate to non-mortgage “other” loan balances. After initial model development produced poor residual behavior due to zero-inflation from imputed debt values, the analysis was refined to include only households reporting verifiable debt. Multiple modeling techniques, including AIC-based variable selection and Lasso regularization, were compared under a five-fold cross-validation framework. The Lasso model achieved superior predictive accuracy (RMSE = 1.55, MAE = …

Liahona Project Data Set 5 Up To 2025, Yoshihiko Ariizumi

Spiritual Proficiency

This document is a collection of highlights extracted from more than 800 articles from the Japanese online Liahona magazines, spanning from the beginning of 2024 to the end of 2025. Each article was individually checked to extract inspirational principles and highlights from personal experiences, serving as a resource to develop Spiritual Proficiency and build the foundation for Wits Psychology (With the Spirit Psychology). The document is 61pages long.