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Fucosylated N-Glycan Landscape Of Triple-Negative Breast Cancer, Danielle A Scott, Souvik Seal, Laura Spruill, Jaclyn Dunne, Graham Colditz, Anand S Mehta, Richard R Drake, Marvella E Ford, Peggi M Angel Dec 2025

Fucosylated N-Glycan Landscape Of Triple-Negative Breast Cancer, Danielle A Scott, Souvik Seal, Laura Spruill, Jaclyn Dunne, Graham Colditz, Anand S Mehta, Richard R Drake, Marvella E Ford, Peggi M Angel

2020-Current year OA Pubs

UNLABELLED: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer lacking targeted therapies. Although aberrant N-glycosylation is a hallmark of malignancy, the specific roles of core-fucosylated (CF) and outer arm-fucosylated (OAF) N-glycans in TNBC progression and patient survival remain underexplored. This study utilized multiplexed glycomics by matrix-assisted laser desorption/ionization imaging mass spectrometry to spatially profile 348 N-glycans in 59 TNBC tumors with clinical characteristics including survival data. Spatial analysis revealed distinct localization patterns of CF and OAF isomers within tumor microenvironments. Strikingly, OAF glycans, but not CF, were strongly associated with tumor stage, with expression increasing from stage …


Proposed Medical School Curricula For 3d Printing, Danielle Heiser, David H Ballard, Et Al. Dec 2025

Proposed Medical School Curricula For 3d Printing, Danielle Heiser, David H Ballard, Et Al.

2020-Current year OA Pubs

BACKGROUND: 3D printing is increasingly utilized in medical education, providing a hands-on approach to anatomical learning, surgical planning, and interdisciplinary collaboration. Despite growing interest, standardized curricula incorporating 3D printing into medical education are lacking.

METHODS: A multidisciplinary team of medical educators, engineers, and students developed three distinct curricular models to integrate 3D printing into undergraduate medical education. These models include (1) integration into anatomy coursework, (2) a fourth-year clerkship elective, and (3) a pre-clerkship elective. The outline for each curriculum was designed to be adaptable across institutions, emphasizing hands-on learning, imaging segmentation, basic elements of computer-aided design (CAD), and 3D …


A Double-Edged Sword: Ethical And Psychological Implications Of Apoe Genotype Disclosure Across The Lifespan, Diego Iacono Dec 2025

A Double-Edged Sword: Ethical And Psychological Implications Of Apoe Genotype Disclosure Across The Lifespan, Diego Iacono

Department of Neurology Faculty Papers

The apolipoprotein E (APOE) gene is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD), with the ε4 allele increasing risk and decreasing the average age of onset. While APOE genotyping is primarily used in research or clinical settings for patients with memory concerns, interest in disclosing APOE status to asymptomatic individuals—particularly during early adulthood—is growing. This trend is fueled by the rise of direct-to-consumer genetic testing and emerging prevention-focused clinical trials. However, ethical debates remain unresolved about the potential harms of early disclosure, including anxiety, stigma, and misunderstanding of probabilistic risk. Conversely, some argue that knowledge of APOE …


The Role Of Religion In Ensuring National Security In Kazakhstan, Nurzhan Arystanbekuly Tursin Nur, Mukhan Issakhan, Shamshadin Kerim, Kovalev Dmitriy, Kalimash Begalinova Dec 2025

The Role Of Religion In Ensuring National Security In Kazakhstan, Nurzhan Arystanbekuly Tursin Nur, Mukhan Issakhan, Shamshadin Kerim, Kovalev Dmitriy, Kalimash Begalinova

Occasional Papers on Religion in Eastern Europe

This article explores the foundations of state policy aimed at ensuring religious stability in Kazakhstan. It analyzes the scientific basis of religious studies, principles of tolerance toward the country’s traditional religions, and the role of religion in maintaining national security. The methodology, goals, and objectives of the study are shaped by the interdisciplinary nature of the subject. The research examines state and interfaith relations, the development of freedom of religion, its integration into domestic and international law, and ways of resolving legal contradictions, traditions, and stereotypes. The theoretical framework relies on the works of domestic and foreign scholars devoted to …


Adventism In The Ukrainian Ssr During The Post-War Period (1946–1952): Structure, Activities, And Relations With The Authorities (A Case Study Of Vinnytsia Region)., Anatoliy A. Voynarovskiy Skiy Dec 2025

Adventism In The Ukrainian Ssr During The Post-War Period (1946–1952): Structure, Activities, And Relations With The Authorities (A Case Study Of Vinnytsia Region)., Anatoliy A. Voynarovskiy Skiy

Occasional Papers on Religion in Eastern Europe

The article contributes to the study of Adventism as a Protestant movement and examines its structure, activities, and interactions with Soviet authorities in the Ukrainian SSR during the post-war period (1946–1952). Particular attention is paid to the organizational characteristics and functioning of the Seventh-day Adventist Church (hereinafter SDA), which, among Ukrainian SSR regions, had the largest number of adherents in Vinnytsia region. In the present-day context of Ukraine’s fight for sovereignty, formation of the national church, and protection of religious freedoms for all citizens, particular attention should be paid to understanding the role of religious institutions in the development of …


The Rhetorical Discourse Of Uniate Writers’ Polemic Literature Of The End Of The 16th – First Half Of The 17th Century In The Retrospection Of Oratory's History, Ruslan Tkachuk Dec 2025

The Rhetorical Discourse Of Uniate Writers’ Polemic Literature Of The End Of The 16th – First Half Of The 17th Century In The Retrospection Of Oratory's History, Ruslan Tkachuk

Occasional Papers on Religion in Eastern Europe

The examination of the poetics inherent in the polemical prose authored by Uniate writers during the late 16th and the first half of the 17th centuries holds substantial significance for comprehending rhetoric as a pivotal element in the stylistic evolution of Ukrainian literature throughout this period. The objective of this article is to explore the interrelationship between the works of Uniate polemicists and the framework of classical rhetoric, particularly by elucidating the functioning of rhetorical figures and argumentation techniques within their texts. To accomplish this aim, a range of literary methodologies were employed. Those methods included historical-cultural, comparative-historical, biographical, structural-analytical, …


The Legal Position Of The Religious Communities In The Republic Of Macedonia, Jovan Jonovski Dec 2025

The Legal Position Of The Religious Communities In The Republic Of Macedonia, Jovan Jonovski

Occasional Papers on Religion in Eastern Europe

The territory of the modern Republic of Macedonia (official name as of recently is Republic of North Macedonia) has historically been exposed to Judaism, Eastern and Western Christianity, Islam, and later to Protestantism. In the People’s /Socialist Republic of Macedonia, the religious communities were kept out of public life and suppressed. The government favored the Macedonian Orthodox Church for strengthening the Macedonian national consciousness. The Republic of Macedonia is a self-declared secular multi-confessional state. The article covers the history of the religious landscape as well as the legal framework and practices of the state toward the Churches, faith communities, and …


Religious Communication In Ukraine's Media Space As Factor In The Formation Of Confessional Identity, Oleh Sokolovskyi, Dmytro Garaschuk Dec 2025

Religious Communication In Ukraine's Media Space As Factor In The Formation Of Confessional Identity, Oleh Sokolovskyi, Dmytro Garaschuk

Occasional Papers on Religion in Eastern Europe

This article presents a comprehensive study within religious studies of religious periodicals in Ukraine from the early 1990s to the present. It attempts to analyze the dynamics of the emergence and transformation of printed religious mass media in the context of the democratization of social life, changes in the information environment, and the development of civil society. It is noted that religious periodicals occupy a special place within the media landscape, since they perform not only the function of conveying information but also tasks of catechesis, spiritual-educational ministry, the formation of value orientations, and the preservation of cultural-historical heritage.

The …


Religion And Human Rights In The Realities Of The Russian-Ukrainian War, Andrii Marchenko Dec 2025

Religion And Human Rights In The Realities Of The Russian-Ukrainian War, Andrii Marchenko

Occasional Papers on Religion in Eastern Europe

The article is devoted to the peculiarities of the relationship between religion and human rights in the context of the Russian-Ukrainian war. It is noted that Russia’s expansion results in a decrease in religious freedom in the temporarily occupied lands, a narrowing of the scope of this fundamental norm. At the same time, the author emphasizes not only the violations of the rights and freedoms of believers in the temporarily occupied territories of the country caused by external factors, but also some internal problems of the socio-religious life of modern Ukraine.The article analyzes the actions of the Ukrainian authorities to …


Orthodoxy, Culture And Language: Alaska In Russia’S Religious Diplomacy Of The 21st Century, Oleksandr Lukyanenko Dec 2025

Orthodoxy, Culture And Language: Alaska In Russia’S Religious Diplomacy Of The 21st Century, Oleksandr Lukyanenko

Occasional Papers on Religion in Eastern Europe

The article is devoted to the analysis of the religious factor of the Russian foreign diplomacy in the light of Vladimir Putin’s high-profile visit to Alaska n August 15, 2025. The paper studies a special place of Alaska in the historical imagination of Russian political and church discourse. The status of this particular territory in Russian state worldview – the former “Russian America” – is indicative: it refers to the idea of an unfinished imperial legacy. The research doesn’t touch a main event that included a meeting with US President Donald Trump but an off-schedule meeting with Archbishop Alexei (Trader) …


Frontmatter (Volume 45, Issue 10), Paul B. Mojzes Dec 2025

Frontmatter (Volume 45, Issue 10), Paul B. Mojzes

Occasional Papers on Religion in Eastern Europe

No abstract provided.


Protests, Epistemic Injustice, And The Movement For Black Lives, Sofia De Ferrari Dec 2025

Protests, Epistemic Injustice, And The Movement For Black Lives, Sofia De Ferrari

PSU McNair Scholars Online Journal

Epistemic injustice provides a powerful perspective for understanding media narratives of the Movement for Black Lives (#BlackLivesMatter). To understand the media coverage, I draw on Foucauldian theories and critical race theory, as well as accounts of hermeneutical and recognition injustice, which show how “truth” emerges as a product of knowledge/power/resistance. Special attention is given to the question of violence: what is violent and what isn’t? Who gets to decide? What are the consequences? Media narratives favor the status quo and delegitimize social movements which challenge it. This is achieved by prioritizing the voices of officials and law enforcement in coverage …


Grendel's Mother Talks Back: Contemporary Women's Mythopoeic Revisions, Anna Smol Dec 2025

Grendel's Mother Talks Back: Contemporary Women's Mythopoeic Revisions, Anna Smol

Mythopoeic Society Seminar Proceedings

"Grendel's Mother Talks Back: Contemporary Women's Mythopoeic Revisions" examines how twenty-first-century feminist adaptations and translations examine the significance and point of view of Grendel's Mother, a character from the Old English poem Beowulf. In contrast to past views of Beowulf, especially in J.R.R. Tolkien's influential essay on the poem, these women writers and scholars argue for the central role of Grendel's Mother and give voice to her story. The paper discusses the main features of these adaptations, covering topics of narrative voice, borderlands, violence, and motherhood, and generally questions the concept of monstrosity as applied to Grendel's Mother. The paper …


Still Perilous, Still Fair: Perspectives On The Legacy, Or How (Not)Eowyn And (Not)Galadriel Made The Magic Work, Janet Croft, Leslie Donovan Dec 2025

Still Perilous, Still Fair: Perspectives On The Legacy, Or How (Not)Eowyn And (Not)Galadriel Made The Magic Work, Janet Croft, Leslie Donovan

Mythopoeic Society Seminar Proceedings

An informal and wide-ranging conversation between the co-editors of Perilous and Fair: Women in the Works and Life of J.R.R. Tolkien will cover the genesis and development of the project and the pitfalls and traps for the unwary we encountered along the way. We'll talk about the technicalities of our process as editors -- from developing the call for papers through choosing the cover art. And we'll assess the influence the collection has had on subsequent scholarship, and the continuing significance of some of the work included.


More Perilous And Fair, Cami Agan, Clare Moore, Robin A. Reid Dr. Dec 2025

More Perilous And Fair, Cami Agan, Clare Moore, Robin A. Reid Dr.

Mythopoeic Society Seminar Proceedings

An overview of the conference's theme and speakers.


Book Review: Ecologies Of Inequity. How Disaster Response Reconstitutes Race And Class Inequality, Abel Traslaviña-Arias Dec 2025

Book Review: Ecologies Of Inequity. How Disaster Response Reconstitutes Race And Class Inequality, Abel Traslaviña-Arias

Critical Disaster Studies

In Ecologies of Inequity: How Disaster Response Reconstitutes Race and Class Inequality, Sancha Doxilly Medwinter gathered diverse stories about how various migrant communities had to overcome not only disaster but also the overlapping networks established by those who were supposed to support them in 2012 in New York City. Medwinter portrays this contested post-disaster landscape through a thorough data recording of 120 individuals affiliated with various groups: racialized migrants or locals, tenants or property owners, local or external helpers, and those from wealthy or impoverished backgrounds. Ecologies of Inequity refer to the spatialized networks of organizational and interpersonal relations …


Upper-Body Post-Activation Performance Enhancement In Mma Athletes: Load-Dependent Effects Across Multiple Explosive Tasks, Jan Strawiński, Dariusz T. Skalski, Magdalena Prończuk, Kinga Łosińska, Ewelina Lulińska, Miłosz Drozd, Maciej Kostrzewa, Adam Maszczyk, Robert K. Roczniok Dec 2025

Upper-Body Post-Activation Performance Enhancement In Mma Athletes: Load-Dependent Effects Across Multiple Explosive Tasks, Jan Strawiński, Dariusz T. Skalski, Magdalena Prończuk, Kinga Łosińska, Ewelina Lulińska, Miłosz Drozd, Maciej Kostrzewa, Adam Maszczyk, Robert K. Roczniok

Baltic Journal of Health and Physical Activity

Background: Post-activation performance enhancement (PAPE) has become a recognized method for acutely improving explosive output, particularly relevant to upper-body performance in combat sports. Objective: This study aimed to evaluate the effects of bench press conditioning activities (CAs) at different intensities (50 %, 65 %, and 80 % 1RM) on upper-body explosive performance in mixed martial arts (MMA) athletes, with emphasis on training status. Methods: Twenty-nine male MMA athletes were divided into intermediate (n = 14) and advanced (n = 15) groups. Each participant completed three CA sessions followed by a 4-minute recovery and then performed a plyometric push-up …


Evaluating Kansai Airport's Ppp: Grounded Ambitions, Concession Of Financial, Geotechnical, And Climate Risk, Edmund Cho, Dimitrios V. Siskos Dec 2025

Evaluating Kansai Airport's Ppp: Grounded Ambitions, Concession Of Financial, Geotechnical, And Climate Risk, Edmund Cho, Dimitrios V. Siskos

International Journal of Aviation, Aeronautics, and Aerospace

This study critically examines the Kansai Airports Group’s 44-year Public-Private Partnership (PPP) monopoly-type concession encompassing Kansai International (KIX), Osaka Itami (ITM), and Kobe (UKB) airports. The research uses financial analysis, Monte Carlo simulation, and NPV-at-risk modeling to evaluate how Japan’s fixed-term private monopoly model allocates financial, operational, and environmental risks. In 2015, there were significant developments in the promotion of the Private Finance Initiative (PFI) Act. It was revised in 2015; as a result, it finds that the underestimated long-term maintenance liabilities, especially Kansai airport (KIX) foundation subsidence, and lacked flexibility to manage exogenous shocks like COVID-19 and Typhoon Jebi. …


Rogue Access Points And Their Impact On Networks, Sami Belmokhtar Dec 2025

Rogue Access Points And Their Impact On Networks, Sami Belmokhtar

Cybersecurity Undergraduate Research Showcase

This paper focuses on rogue access points (rogue APs) and how they can impact the security and stability of a network, and consequently, the safety and privacy of the users. Wireless access points (WAPs) are nodes that allow a user to connect to a local network. This includes devices such as the routers typically used in a home network. This paper examines how an unauthorized WAP may pose a threat to a network in both a public environment and an enterprise environment. Furthermore, it shows how a hacker can mimic a real wireless network and gain access to both user …


A Transition Framework For Hybrid Tls In Enterprise-Level Systems, William Hadd Dec 2025

A Transition Framework For Hybrid Tls In Enterprise-Level Systems, William Hadd

Cybersecurity Undergraduate Research Showcase

Enterprises face an immediate need to protect long-lived data against harvest-now, decrypt-later threats while maintaining interoperability across layered systems. With NIST’s first post-quantum standards finalized (ML-KEM, ML-DSA, SLH-DSA) and TLS hybridization drafts defining concrete ECDHE + ML-KEM groups, adoption can begin at the TLS termination layer even before full ecosystem support for post-quantum signatures arrives (NIST, 2024; IETF, 2025). In this paper, we propose an enterprise-oriented transition framework and maturity model for hybrid TLS across email, internal API gateways, and object storage. We specify where to enforce, which hybrid groups to select, and how to prevent silent downgrade with policy …


The Legal And Ethical Impacts Of Cybersecurity Practices On Privacy And Digital Rights, Ibrahim Fejzulla Dec 2025

The Legal And Ethical Impacts Of Cybersecurity Practices On Privacy And Digital Rights, Ibrahim Fejzulla

Cybersecurity Undergraduate Research Showcase

The General Data Protection Regulation (GDPR) and the Health Insurance Portability and Accountability Act (HIPAA) are meant to secure our data, but sometimes it feels as if organizations don’t do enough to secure and protect our data and privacy. Even some of the things organizations may do to improve security may sound counterintuitive like hiring ethical hackers or penetration testers. This research looks at the effects both, the GDPR and HIPAA, have had on cybersecurity practices and policies of organizations. This paper aims to analyze the effects of both the GDPR and HIPAA, answer whether ethical hacking is justified, analyze …


Taking A Trip Into Nature’S Medicine Cabinet: A Country Comparison Of Efforts To Reschedule Psilocybin And Mdma For Therapeutic Use, Ariyah Jones Dec 2025

Taking A Trip Into Nature’S Medicine Cabinet: A Country Comparison Of Efforts To Reschedule Psilocybin And Mdma For Therapeutic Use, Ariyah Jones

Georgia Journal of International & Comparative Law

No abstract provided.


A Comparison Between American And Hong Konger Regulatory Efforts Of Cryptocurrency Exchanges In The Light Of The Bankruptcy Of Ftx Trading Ltd., Patrick Johnson Dec 2025

A Comparison Between American And Hong Konger Regulatory Efforts Of Cryptocurrency Exchanges In The Light Of The Bankruptcy Of Ftx Trading Ltd., Patrick Johnson

Georgia Journal of International & Comparative Law

No abstract provided.


Arbitrating Business And Human Rights Disputes In Latin America, Gloria Correa Dec 2025

Arbitrating Business And Human Rights Disputes In Latin America, Gloria Correa

Georgia Journal of International & Comparative Law

No abstract provided.


Unclos: Developments In Regulations On Deep-Sea Mining In International Waters, Logan Berg Dec 2025

Unclos: Developments In Regulations On Deep-Sea Mining In International Waters, Logan Berg

Georgia Journal of International & Comparative Law

No abstract provided.


Lunar Servicing, Assembly, And Manufacturing; Legal And Environmental Issues, Francesca Giannoni-Crystal Dec 2025

Lunar Servicing, Assembly, And Manufacturing; Legal And Environmental Issues, Francesca Giannoni-Crystal

Georgia Journal of International & Comparative Law

No abstract provided.


The Internet Of Hate: Comparing The Nature, Harms, And Regulatory Challenges Of Online And Offline Hate Speech, Alexander Brown Dec 2025

The Internet Of Hate: Comparing The Nature, Harms, And Regulatory Challenges Of Online And Offline Hate Speech, Alexander Brown

Georgia Journal of International & Comparative Law

No abstract provided.


Fundamental Fairness Guides The Supreme Court's Criminal Justice Decisions In The 2024-2025 Term, Sharon R. Fairley Dec 2025

Fundamental Fairness Guides The Supreme Court's Criminal Justice Decisions In The 2024-2025 Term, Sharon R. Fairley

ConLawNOW

During the 2024-2025 term, the Supreme Court decided fifteen cases related to the criminal justice system. These cases were brought by criminal defendants seeking post-conviction relief and civil litigants seeking redress for governmental harms arising out of criminal processes. Remarkably, two-thirds of the cases resulted in decisions favoring defendants or civil litigants opposing the government. This Article argues that the pro-defendant outcomes from this term are consistent with a recent trend in the Court’s decisions favoring defendants in these types of cases. The pro-defendant outcomes from the 2024-2025 term generally resulted from the less conservative justices aligning with the liberal …


The Tax Adviser, Volume 1, Number 2, February 1970, American Institute Of Certified Public Accountants Dec 2025

The Tax Adviser, Volume 1, Number 2, February 1970, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.


Tax Trends, Harry Z. Garian Dec 2025

Tax Trends, Harry Z. Garian

Tax Adviser

No abstract provided.