Digital Commons Network^™

Executive Function Among Older Adults With Bipolar Disorder: A Gage-Bd Analysis, Federica Klaus, Martha Sajatovic, Peijun Chen, Nicole Fiorelli, Ashley N. Sutherland

Faculty Scholarship

Objectives Executive function deficits in bipolar disorder (BD) are major contributors to disability in older age BD (OABD). We investigated the difference between OABD and age-equated healthy comparators (HC); and, in the OABD group, the associations of executive function with age, symptom severity, global cognition, and daily functioning. Design Cross-sectional analysis of executive function in OABD versus HC. Setting Analysis of large archival dataset harmonized from 12 international OABD studies. Participants Older adults (≥50 years) with OABD ( n = 614) and HC ( n = 192). Measurements Executive function was assessed via Trail Making Test B (TMT-B) completion time; …

Personalized Perioperative Opioid Strategies In Children: Focus On Methadone, Pharmacogenomics And Prevention Of Persistent Postoperative Opioid Use, Hamsa Priya Bhuchakra, Sennaraj Balasubramanian, Alivia G Nair, Isabella Marcos, Victoria Chen Falconett, Dominic Falcon, Ayesha Abdul Bari, Senthilkumar Sadhasivam

2020-Current year OA Pubs

Persistent postoperative opioid use (PPOU) is an emerging challenge in pediatric perioperative care, with rates as high as 4.7% in opioid-naive adolescents. Despite advances in multimodal analgesia, current protocols often fail to prevent long-term opioid exposure, particularly after high-risk surgeries such as spinal fusions. While multiple strategies exist to reduce PPOU in children, including regional anesthesia and non-opioid analgesics, this review specifically focuses on methadone and pharmacogenomic-guided opioid prescribing as promising approaches. Methadone, a long-acting opioid with mu-opioid agonism, NMDA antagonism, and monoamine reuptake inhibition, has shown encouraging outcomes in adult and emerging pediatric studies but remains underutilized due to …

Insm1 Governs A Neuronal Progenitor State That Drives Glioblastoma In A Human Stem Cell Model, Patrick A Desouza, Matthew Ishahak, Xuan Qu, Colin Mccornack, Devi Annamalai, Diane D Mao, Rajanikanth Vangipurapu, Yiwei Fu, Alexandre T Vessoni, Ryan T Cleary, Rowland H Han, Punn Augsornworawat, Timothy Woodiwiss, Darby Agovino, Braxton Sizemore, Jessica Kline, Maryam Borhani-Haghighi, Hao Chen, Sangami Pugazenthi, Hiroko Yano, Ting Wang, Luis F Z Batista, Jeffrey R Millman, Albert H Kim

2020-Current year OA Pubs

Glioblastoma is a lethal brain cancer marked by functional plasticity driven by tumor cell-intrinsic mutations and their interplay with developmental programs. To investigate how canonical glioblastoma mutations promote functional plasticity, we have developed an isogenic human neural stem cell (NSC) model of glioblastoma by sequential addition of TERT promoter, TP53, and PDGFRA point mutations. TP53 loss-of-function increases TERT expression during serial mutagenesis, but only triple mutant NSCs reliably form lethal brain tumors in vivo that recapitulate glioblastoma. Tumor cell evolution triggers stress-related metabolic changes and transitions toward a neuronal progenitor network driven by transcription factor INSM1. INSM1 is highly expressed …

Ai Literacy For Nurse Leaders: Advancing Innovation And Transforming Care, Carolyn S. Harmon

Biennial Convention (CONV)

With the rapid integration of artificial intelligence (AI) in healthcare, it is imperative for nurse leaders to develop AI literacy to effectively lead and manage their teams. This presentation explores the significance of AI literacy for nurse leaders, focusing on the benefits of understanding AI technologies and their applications in nursing practice. By equipping nurse leaders with the knowledge and aptitudes to navigate AI systems, healthcare organizations can advance clinical decision-making, streamline administrative workflows, and achieve transformative improvements in care delivery.

The purpose of this presentation is to highlight the critical role of AI literacy in nursing leadership and to …

Economics Of The Olympics: Impact Of Bidding For And Hosting The Olympic Games On International Openness, Adalynn Cherry

Pennsylvania Economic Review

This study investigates how hosting and unsuccessfully bidding to host the Olympic Games impacts total international trade and influences a country’s openness. This relationship is analyzed using the gravity model of trade to perform a regression analysis of total trade levels from 2000 to 2018. The results of this study did not support the idea that hosting the Olympic Games impacts total trade; although, they did show a strong and permanent positive relationship between unsuccessfully bidding to host the Olympic Games and total international trade. These findings highlight the benefits of the Olympic bidding and candidature process as a policy …

Masters At Chapman: Dance And Fashion

Dance Programs

No abstract provided.

Examining The Intersectional And Structural Issues Of Routine Healthcare Utilization And Access Inequities For Lgb People With Chronic Diseases, Shiya Cao, Mehreen Mirza, Sophia Silovsky, Nicole Tresvalles, Lucia Qin, Sarah Susnea

Statistical and Data Sciences: Faculty Publications

In the United States, although the gaps in health insurance coverage by sexual orientation have been closing since the implementation of the Affordable Care Act and legalization of same-sex marriage, the LGB group (i.e., lesbian, gay, bisexual) continues to report healthcare utilization and access inequities such as more delayed or unmet care. The extant research has often examined healthcare utilization and access inequities due to affordability (e.g., out-of-pocket costs). However, healthcare utilization and access inequities are only partially explained by cost reasons; there are non-cost reasons that have not been adequately empirically examined. The present study innovatively includes discrimination structural …

The Safety Kuznets Curve: Context In Occupational Safety, Andy Knickerbocker

ASEM Capstones

2025 ASEM 620 Capstone Project

Integrating A “World -Class” Safety System Into Diverse Teams, Mark D. Keller

ASEM Capstones

2025 ASEM 620 Capstone Project

Holiday Concert

Bailey School of Music Concert Programs

Celebrate the season with an unforgettable evening of music and cheer! Join the Bailey School of Music student ensembles, featuring the Chamber Singers, Jazz Ensemble I, Symphony Orchestra and Wind Ensemble for a festive performance packed with holiday favorites the whole family will love. From timeless classics to joyful surprises, this concert is sure to warm your heart and lift your spirits.

Experiences Of Non-Hispanic Black And African American Women With Postpartum Healthcare, Margaret F. Sposato, Claire Draucker, Jasmine D. Johnson, Kristin Tully, Julie Otte

Biennial Convention (CONV)

Racial and ethnic disparities in maternal mortality and morbidity are stark in the United States, especially for non-Hispanic Black and African American women who experience elevated rates of pregnancy-related deaths and severe maternal morbidity.^1,2 Effective postpartum healthcare is essential for optimizing birthing people’s health,³ yet little is known about non-Hispanic Black and African American women’s experiences with postpartum healthcare in the year following delivery. The purpose of this study was to describe non-Hispanic Black and African American women’s experiences with postpartum healthcare throughout the one-year postpartum period from their perspectives. For this qualitative descriptive study semi-structured interviews with …

Rebuilding Trust In The Used Car Industry: A Five Forces Analysis, Ghaika Vera

Honors Capstones

Consumer distrust has become one of the greatest barriers to success in today’s automotive retail environment, especially within the used-car market where skepticism toward dealerships and repair services is widespread. This research investigates how dealerships can rebuild consumer confidence while also improving profitability and long-term competitive positioning. Using Porter’s Five Forces framework, the study analyzes key industry pressures including high buyer power, strong competitive rivalry, and increasing substitute transportation. Findings show that transparency, trust-building communication, and consistent relationship-based service are essential for sustainable differentiation. Strategies such as mobile-friendly scheduling systems, real-time repair updates, transparent pricing and inspection visuals, partnerships with …

Tennyson & Contemporary Science: Herschel’S Preliminary Discourse, A Book That Got Away, Patrick Scott

Faculty Publications

Discusses the rediscovery, provenance, and authenticity of the copy of John Herschel's Preliminary Discourse on the Study of Natural Philosophy (1831), with an ownership inscription by Tennyson dated 1843, and marginal markings on multiple pages, that was previously only known from a brief catalogue description for a 1924 auction.

Closeness, Conflict, And Achievement: The Role Of Parent–Child Relationships In Homeschooled And Public-Schooled Children, Celeste Gonçalves Tomaz

Honors Capstones

The parent–child relationship has been found to be a predictor of children’s academic and socio-emotional outcomes, with parent-child closeness linked to motivation and persistence (Mo & Singh, 2008; Silinskas & Kikas, 2022) and parent-child conflict associated with emotional and behavioral difficulties (Dotterer et al., 2008; Pinquart, 2017). The homeschooling context may increase these associations since children spend more time with their parents, who have caregiving and instructional roles (Padilla, 2021; Thomas, 2016). Even with growing research on academic and socio-emotional outcomes, few studies have examined whether the strength of the parent–child relationship is influenced negatively or positively by schooling type. …

State Of Technology Usage In Smaller Public Accounting Firms In 2025, Arun Kumararaj, Candice Hux

Honors Capstones

Prior research gives significant attention to technology usage of large public accounting firms, particularly the Big 4. However, limited evidence exists on the smaller public accounting firms, which constitute a majority of the public accounting field. In this study, we conducted semi-structured interviews with eight highly experienced professionals of smaller accounting firms. Findings reveal that firm size does not necessarily predict technological sophistication. Rather, individual leadership, including a single partner, emerges as a critical driver towards technological advancement. AI was primarily used for administrative tasks and, as of yet, the return on investment has been unclear. Despite this, all interviewees …

Ract: Ranking-Aware Chain-Of-Thought Optimization For Llms, Haowei Liu, Xuyang Wu, Guohao Sun, Hsin-Tai Wu, Zhiqiang Tao, Yi Fang

Computer Science and Engineering

In information retrieval, large language models (LLMs) have demonstrated remarkable potential in text reranking tasks by leveraging their sophisticated natural language understanding and advanced reasoning capabilities. However, conventional supervised fine-tuning approaches for specializing LLMs in ranking tasks often lead to significant degradation of the models' general-purpose abilities. To address this fundamental challenge, this paper presents a novel methodology that strategically combines Chain-of-Thought (CoT) prompting techniques with an innovative two-stage training pipeline consisting of Supervised Fine-Tuning followed by Ranking Preference Optimization (SFT-RPO). The Chain-of-Thought prompting component encourages models to explicitly articulate their reasoning process during ranking decisions, creating a transparent pathway …

Strategies For Prolonging Ventricular Action Potential Duration Without Increasing Transmural Dispersion Of Repolarization, Candido Cabo

Publications and Research

Dispersion of repolarization results from a non-homogeneous recovery of excitability in cardiac tissue, and it is an important factor in arrhythmogenesis because it could lead to the initiation and maintenance of a variety of arrhythmias. Antiarrhythmic agents that prolong action potential duration (APD) by selectively blocking specific ion channels (like IKr) often increase dispersion of repolarization, which could result in a pro-arrhythmic risk. In this report, using computer models of the action potential of human epicardial, mid-myocardial, and endocardial myocytes, we have identified strategies to prolong APD without increasing transmural dispersion of repolarization. The first strategy, which involves blocking several …

Changing Opinions: The Supreme Court After Dobbs, Lora E. Judge

Honors Theses

No abstract provided.

The Reception Of Neurodiversity Represented Within Netflix’S Wednesday, Anna Stevens

Graduate Theses & Dissertations

This paper explores how neurodiversity is represented through popular media - particularly Netflix's show Wednesday - and aims to discuss the effects this representation could have in regards to how it's received by the public, as well as those who are neurodiverse.

Proteome-Wide Association Study Of Prostate Cancer Risk Across Populations, Hua Zhong, Jingjing Zhu, Shuai Liu, Chong Wu, Liang Wang, Seamus P. Whelton, Catherine H. Marshall, Michael J. Blaha, Peter Durda, Xiuqing Guo, Craig W. Johnson, Henry J. Lin, Kent D. Taylor, Russell P. Tracy, Ronit I. Yarden, Ani W. Manichaikul, Stephen S. Rich, Jerome I. Rotter, Rajat Deo, Ruth F. Dubin, Peter Ganz, Lang Wu

School of Graduate Studies Faculty Publications

There is insufficient understanding of the molecular basis of prostate cancer (PCa) across different populations. We perform a large-scale proteome-wide association study (PWAS) to identify proteins with genetically regulated expression in plasma to be associated with PCa risk across populations. We develop genetic prediction models for expression of 1578, 1993, 1218, and 1390 proteins for African (n = 450), European (n = 758), Asian (n = 289), and Hispanic/Latino (n = 474) males, respectively, and evaluate associations of genetically regulated protein expression with PCa risk in 19,391 PCa cases and 61,608 controls of African population, 122,188 cases and 604,640 controls …

Elm: The Case Of Experiential Programming, Matthew Miller, Lynette Campogiani

Faculty and Staff Publications & Presentations

Experiential Programs (EPs) provide immersive, destination-focused experiences within luxury resort settings. However, research has yet to apply the elaboration likelihood model (ELM) to examine how guests evaluate their experiences with EPs, particularly within luxury tourism or resort contexts. Using the ELM framework, this study examined how the experience of luxury resort EPs influences guests’ revisit intentions. Guests’ experiences were categorized into central and peripheral processing cues and qualitative interview responses were analyzed. The findings indicate that elements such as ambient music and scenic views associated with peripheral processing had a significantly stronger positive impact on guests’ intentions to return than …

An Updated Annotated Checklist Of The Mammals Of The Crane Trust, Hall County, Nebraska, Bethany L. Ostrom, Amanda H. Medaries, Andrew J. Caven, Jenna M. Malzahn, Alexa Rojas, Matthew R. Schaaf, David M. Baasch, Thomas E. Labedz, Greg D. Wright

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

The Crane Trust is a regional nonprofit conservation organization that has protected land in the biologically important Central Platte River Valley for over four decades. A mammal inventory was conducted on the Crane Trust’s main habitat complex in 1980. Since, a variety of environmental conditions have shifted locally, regionally, and globally. An analysis of the mammal community was conducted using past and recent data to determine how species composition and relative abundance have shifted categorically from 1980 to 2021. We used all available data to categorize relative abundance during two distinct time periods per a modified “DAFOR” scale including 7 …

Characterization Of Peg-Modified Composite Membranes For Microfluidic Oxygenator Applications, Nicholas C. Higgins, David G. Blauvelt, Shuvo Roy

Department of Pediatrics Faculty Papers

Microfluidic oxygenators promise to advance extracorporeal membrane oxygenation (ECMO) devices with enhanced hemodynamics and low prime volume. We are developing a silicon-based membrane oxygenator that will offer improved gas transfer and fluid flow control. Polyethylene glycol (PEG) has been used to improve hemocompatibility by providing excellent resistance to protein adsorption. Here, we characterized a polyethylene glycol surface modification of composite silicon–PDMS membranes to evaluate their effects on microfluidic oxygenator properties. X-ray photoelectron spectroscopy (XPS) and water contact angle goniometry confirmed successful PEG attachment, evidenced by the presence of characteristic C-O bonds and increased hydrophilicity, which was stable for 2 weeks. …

Hospital Length Of Stay In Sepsis Patients Across Age, Comorbidity, And Invasive Device Use Categories, Heri Sutanto, Alif Nurul Izzati, Syifa Mustika

Folia Medica Indonesiana

Sepsis is a life-threatening condition caused by a dysregulated response of the body to infection. Sepsis is closely associated with high costs and prolonged length of hospitalization. The purpose of this study was to determine the correlation between sepsis risk factors and length of hospitalization for sepsis patients at Dr. Saiful Anwar Malang General Hospital. This study used a retrospective cohort approach with a sample size of 56 medical records. The study used inclusion criteria for sample selection. The analysis results in a p-value of 0.976 and an r-value of 0.004; the findings demonstrated a correlation between patient age and …

Evaluation Of Antibacterial Activity Of Amaranthus Spinosus Extract Against Streptococcus Mutans: An In-Vitro Study, Fakhrun Nisa, Juen Carla Warella, Valentine Hursepuny, Johan Bruyif Bension, Khairunnida Rahma

Folia Medica Indonesiana

Streptococcus mutans is a component of the normal oral flora that can become a primary pathogen, leading to dental caries and tooth decay. Tooth decay and dental caries are the most common oral health issues worldwide. Treatment of dental caries and tooth decay represents a crucial effort in addressing global health concerns. One alternative treatment the community used to treat dental caries and tooth decay is thorn spinach (Amaranthus spinosus). Thorn spinach leaves contain bioactive compounds with potential antibacterial properties, including flavonoids, tannins, saponins, and alkaloids. This study aimed to evaluate the antibacterial activity of thorn spinach leaf …

Factors Associated With Medication Adherence And Systolic And Diastolic Blood Pressure Of Hypertensive Patients, Hamka Ziddan, Meity Ardiana, Linda Dewanti, Anudya Kartika Ratri

Folia Medica Indonesiana

Uncontrolled hypertension can cause complications such as heart disease, brain disease, kidney disease, and other diseases. Medication adherence is a primary factor in controlling blood pressure (BP) in hypertensive patients. This study aims to provide an overview of the factors associated with medication adherence of hypertensive patients treated at Taman Public Health Center in Sidoarjo, Indonesia. This study used a cross-sectional approach involving hypertensive patients. This study employed consecutive sampling, with the number of samples comprised of patients undergoing outpatient care from January 2, 2023, to February 25, 2023, totaling 103 respondents. The study employed the Morisky Medication Adherence Scale …

The Formation And Dynamics Of Colonial “Lived Spaces” : Urban Space And Society In Colonial Hanoi, 1883–1916, Nam Khanh Hoang '25

Student Research

This study examines the nuanced experiences and perceptions of urban space among different social groups in colonial Hanoi in the late nineteenth and early twentieth centuries by analyzing the French colonial agendas, as reflected through modern urban planning and practices, and its reception among the colonial urban inhabitants, as suggested through their responses to the Statue of Liberty—a colonial urban monument. While existing scholarship has often framed colonial cities as stages for consolidating imperial power, introducing Western ideals of modernity, and forming systems of oppression and exploitation against colonial subjects, it has often overlooked the perceptions and experiences of colonial …

Double Burden Stress In Women And The Role Of Psycho-Religious Worship In Alleviating It, Fahmi Mandala Putra, Zata Ismah, Rizky Indah Syahfitri, Citra Cahyati Nasution, Az-Zahra Atika Putri, Fitria Amirah, Tri Amelia Rahmitha Helmi

Folia Medica Indonesiana

It has been recognized that women are twice as likely to experience depression compared to men. In addition to biological vulnerability, there is also a combined effect of bearing the burden of household responsibilities while contributing financially through employment. One coping strategy that helps women endure these challenges is meditation, which in Islam includes the practice of dhikr (remembrance of God). This study aims to analyze the phenomenon of double burden stress in women and how psychoreligious practices can help reduce stress levels. The study employed a prospective cohort design, tracking the respondents' dhikr habits over a 21-day period. On …

Innovative Offshore Transition-To-Practice Model For International Nurses Using Tele-Simulation, Lisa Mceathron, Christian Striggow, Jose Arnold Tariga

Biennial Convention (CONV)

Empirical evidence underscores the importance of optimal nurse staffing in delivering high-quality patient care, improving outcomes, and enhancing nurse well-being. Internationally educated nurses (IENs) play a crucial role in addressing staffing shortages in the United States, yet they face challenges in bridging gaps between varying international nursing standards and US healthcare practices. Innovative approaches are essential to ensure their readiness to integrate effectively prior to arrival.

The International Transition to Practice Program leverages tele-simulation as a pioneering strategy to address these challenges, providing an offshore, immersive learning experience for IENs. This program was implemented from July 2023 to September 2024, …

Improving Hiv Knowledge And Attitudes Of The Youth In The Philippines Through Mobile Text Messaging, James Montegrico

Biennial Convention (CONV)

Background: The Philippines has the highest HIV incidence rate in the Asia-Pacific region, with the highest incidence between the ages 15 to 34 years. There are low levels of HIV knowledge, negative attitudes towards people with HIV/AIDS, and a lack of interventional studies to improve HIV knowledge and attitudes in the country. The high rate of mobile phone use and text messaging in the Philippines offers potential in using technology to address gaps in HIV knowledge and negative attitudes regarding HIV.

Purpose: This pilot study determined the feasibility and effectiveness of mobile text messaging (MTM) in improving HIV/AIDS knowledge …