Digital Commons Network^™

Methylation-Based Signature To Distinguish Indolent And Aggressive Prostate Cancer, Muheng Liao, Jace Webster, Amy Ly, Emily Rozycki, Christopher A Maher

2020-Current year OA Pubs

Prostate cancer management faces significant challenges in distinguishing indolent from aggressive disease, particularly since most patients are intermediate-risk and therefore hinders the ability to recommend standardized treatment recommendations. Moreover, current prognostic tools including Gleason scoring and tumor staging demonstrate limited accuracy for predicting disease progression and tumor recurrence. DNA methylation serves as a stable epigenetic modification that directly regulates gene expression, making it an ideal biomarker for cancer prognosis. Therefore, this study leveraged whole-genome enzymatic methylation sequencing on 120 patients to develop a novel prognostic signature for aggressive prostate cancer progression. We analyzed 20,849 differentially methylated regions (DMRs) and employed …

How Climate For Green Initiatives Drives Eco-Innovative And Citizenship Behaviours: The Role Of Green Engagement And Green Values, Aaron Makafui Ametorwo, Michael Kyei-Frimpong, Abdul Razak Suleman

Research outputs 2022 to 2026

Purpose This study proposes and tests the nexus between climate for green initiatives, green innovative behaviour, organisational citizenship behaviour for the environment, green work engagement, and individual green values. Design/methodology/approach The study adopted the explanatory research design, where data were gathered from 374 star-rated frontline employees at two different waves within a one-month interval. The data retrieved from the respondents were analysed using descriptive and inferential (partial least squares structural equation modelling) statistics. Findings The study revealed that a climate for green initiatives positively and significantly relates to green innovative behaviour and organisational citizenship behaviour for the environment. Also, the …

Gender Equality Discourse: A Japanese Context, Gabriel Eweje, Hitomi Toyosaki, Kazunori Kobayashi, Sitong Michelle Chen, Masahiro Hosoda

Research outputs 2022 to 2026

Purpose – This review paper aims to critically examine the discourse on gender equality in Japan, focusing on its socio-cultural, economic and political dimensions. By synthesising existing literature, it provides a comprehensive understanding of the complexities and barriers that influence the gender equality debate in Japan, while identifying gaps and opportunities for future research and specifying where practice can be recoupled to policy. Design/methodology/approach – An integrative literature review was conducted across four key institutional domains – markets, government/public sector, families and education – analysed at the macro, meso and micro levels. The synthesis is integrative rather than exhaustive, prioritising …

The Negotiation Of Identities Through Humorous Discourse In Political Resistance: An Analysis Of Bassem Youssef's 'The B+ Show', Howaida Aref

Theses and Dissertations

This study examines the strategic use of humorous discourse in negotiating identities and expressing political resistance during the 2011 Egyptian Revolution, focusing on Bassem Youssef's satirical YouTube show, "The B+ Show." Employing a mixed-method approach that combines Grice's maxims of cooperative communication and Fairclough's critical discourse analysis framework, the research investigates how humor functioned as a tool for challenging hegemonic narratives and power dynamics through constructing and deconstructing identities in a volatile sociopolitical context. The analysis reveals that Youssef skillfully exploited various discursive resources, particularly intertextuality and the flouting of conversational maxims, to generate implicatures that effectively debunked negative representations …

Maritime Trade And Imperial Ambitions: Yemeni Politics And Trade In The Indian Ocean World (626/1228-858/1454), Beck Sjostedt

Theses and Dissertations

This thesis explores the role of Yemen, particularly under the Rasūlid dynasty (626/1228-858/1454) in the medieval Indian Ocean trade. I argue that the Rasūlids attempted to create an “imperial maritime space” wherein Yemen would be the imperial core, and the western Indian Ocean and Red Sea the subjugated peripheries. While the Rasūlids managed to organize state power towards their imperial project via diplomacy, military and naval expansion, and a robust and efficient bureaucracy, they never fully realized their goal of creating a thalassocratic empire in the western Indian Ocean. Nonetheless, medieval Yemen played a significant role in the political, social, …

The Cost Of Care: Medical Bills, Mental Health, And The Protective Role Of Insurance Coverage Among U.S. Adults, Fahima Sultana

Electronic Theses and Dissertations Archive

This paper focuses on how medical bills and financial hardship are related to healthcare access in adults in the United States, based on the results of the National Health Interview Survey (NHIS). In particular, it examines the hypothesis that those with problems paying medical bills have a higher tendency to delay or ration medical care or health insurance cover offsets this effect. Logistic regression models were used to determine the relationship between financial hardship, delayed care, and psychological distress and demographic and socioeconomic variables including age, education, race, and poverty status. According to the results, it can be seen that …

Breaking Barriers: Understanding Factors Constraining Women’S Career Choices And Progression In The South African Construction Industry, Abimbola Olukemi Windapo, Olugbenga Timo Oladinrin, João Alencastro, Dineo Mbekwa, Christiana Ekpo, Muhammad Qasim Rana, Amanda Filtane

School of Art, Design and Architecture

Purpose – This paper examines the barriers constraining women's career choices and progression within the South African construction industry. Design/methodology/approach – The study employed a mixed-methods research approach, utilizing a questionnaire survey of construction industry workers listed in the Construction Professions Register, the Builders Collective and the Housing Assembly Organization. It also used interviews to validate the quantitative data. The data collected were analysed using descriptive and inferential statistics, including factor analysis. Findings – The study found that 39 of the 46 barriers identified have normalized values greater than 0.5 and, therefore, are classified as critical. From a ranking perspective, …

Information Management / Bim Technology Deployment Plan, Robert Moore

Tools

This technology deployment plan sets out the practical steps required to implement and operationalise selected Information Management and BIM (BIM) technologies. It defines activities, responsibilities, sequencing, and dependencies to ensure systems are configured, tested, and adopted in a controlled and coordinated manner. The plan supports effective change management, training, and transition to business-as-usual use, reducing risk and disruption. Overall, it provides a clear, actionable framework for moving from technology selection to consistent, reliable use that supports standards-aligned Information Management / BIM delivery.

Information Management / Bim Adoption And Implementation Roadmap, Robert Moore

Tools

This roadmap sets out a clear, practical approach for organisations to adopt and implement Information Management and Building Information Modelling (IM/BIM) in line with ISO 19650 and the Capital Works Management Framework (CWMF). It provides a phased pathway from early capacity to advanced capability, showing how organisations can progressively build skills, processes, and digital workflows while meeting the requirements of the Irish BIM mandate. The roadmap aligns organisational change with project-level delivery, emphasising the foundations of people, process, and technology, and the importance of collaboration, governance, and continuous improvement. Overall, it supports organisations in moving from basic information management to …

Verbs With Augmented Antonyms In The Lisan Al-Arab Dictionary, Mahmoud Alwan Mahmoud, Ali Heloo Hawas

Alustath Journal for Human and Social Sciences

It is human nature to question the underlying causes of any phenomenon, regardless of its type, and to seek to interpret it through judgments deemed logical by the researcher. Reasoning is a fundamental pillar of research methodology. Several phenomena have emerged in the Arabic language that one group of scholars considers a linguistic feature, while another views as a linguistic weakness. Among these phenomena is the concept of "contradictory verbal participles," traditionally referred to as "antonyms" (al-ʾaḍdād). These are words that convey two opposite meanings, such as "black and white" or "menstruation." Scholars have debated the existence of this phenomenon …

The Development Of Children's Understanding Of Merit In The Fair Allocation Of Resources, Zahraa Sami Abboud, Ghada Ali Hadi

Alustath Journal for Human and Social Sciences

The current research aims to identify: 1- Children’s understanding of merit in the fair allocation of resources according to the variables: A- Age (4, 5, 6, 7, 8, 9, 10) years. B - Gender (males - females). 2- There are statistically significant differences in children’s understanding of merit in the fair allocation of resources according to the two variables: A - Age (4, 5, 6, 7, 8, 9, 10) years. B - Gender (males - females). The current research sample includes (280) boys and girls of Baghdad Governorate- its two sides (Karkh and Rusafa), for ages (4, 5, 6, 7, …

Suicidal Intentions Among Divorced Women In Wasit Province, Khitam Abbas Fadhel, Hassan Aii Ai-Sayed

Alustath Journal for Human and Social Sciences

The current research aims to: Identifying Suicidal Intentions Among Divorced Women Marriage is viewed as a social institution that includes a set of norms regulating the relationship between spouses. The strength of this structure relies on solid foundations such as proper selection and compatibility in social aspects. Marriage imposes on spouses a set of mutual obligations and rights ensuring the continuity of marital life and enabling the family to fulfill its basic functions Despite the psychological, health and social significance marriage, offers to individuals and society, the phenomenon of divorce has been increasingly prevalent in recent times across various communities …

Myth In The Poetry Of Hassan Abd Rady, Zahraa Mousa Jabbar Aayed, Iman Mohammed Ibrahim Al-Obaidi

Alustath Journal for Human and Social Sciences

This research reviews the topic of (Myth in the Poetry of Hassan Abd Rady), as the myth received the attention of contemporary poets as an important source that enriches their poetic texts and deepens their connotations. The poet Hassan Abd Rady invoked myth in all its forms to enrich his poetic texts because of the suggestive connotations it carries. The research included the following: the introduction and the preface, in which the myth was defined linguistically, terminologically, and its types. The research was divided into the number of myths employed by Abd Radi, including: Greek myth, Babylonian myth, Greek myth, …

What’S In A Group: A Social Science Inquiry, Maria Caridad H. Tarroja

Asia-Pacific Social Science Review

No abstract provided.

Investigating Community Attachment, Quality Of Life, And Community Citizenship Behavior Toward Rural Tourism Development In Thailand, Supaporn Prasongthan, Pimonphat Rodtook, Jariya Supun, Rabhas Silpsrikul

Asia-Pacific Social Science Review

In rural tourism destinations, residents serve as representatives of the area, and their involvement in tourism and discretionary behavior contributes to the destination’s success. The objectives of this study were to explore the community citizenship behavior (CCB) model and to examine the relationship among residents’ attachment, quality of life (QOL), and five dimensions of CCB, including involving, keeping interpersonal harmony, protecting, helping, and recommending behavior, across two stages of rural tourism destinations in Thailand. A multivariate quantitative research method was employed. A total of 1,052 samples were retrieved from residents living in 10 selective rural tourism destinations, with 526 respondents …

The Economics Of Homelessness: A Quantitative Study On Homeless Willingness To Pay For Affordable Housing In Thailand, Peera Tangtammaruk, Nattapon Siwareepan, Jennifer Chavanovanich, Nartsupon Dumchuen, Thanee Chaiwat, Mattana Wongsirikajorn

Asia-Pacific Social Science Review

This study investigates the willingness to pay (WTP) for housing among homeless individuals in Thailand, using the contingent valuation method (CVM) and a structured choice experiment model. Data were collected through face-to-face interviews with 90 homeless individuals from Bangkok, Chiang Mai, and Khon Kaen. The study aims to understand the economic value that homeless individuals are willing to pay for various types of homelessness-related housing, as well as the factors influencing their WTP. The findings reveal that while most homeless individuals express a preference for affordable rental housing, their financial capacity remains limited due to low and unstable incomes. The …

From Cultural Enthusiasm To Academic Institutionalization: The Rise And Limitations Of Korean Studies In Taiwan’S Higher Education, Bumsig Ha, Hsien-Ming Lin

Asia-Pacific Social Science Review

This study explores the institutionalization, development, and ongoing challenges of regional studies in Taiwan’s higher education system, with a specific focus on Korean Studies. It examines how Taiwan’s growing interest in South Korea, shaped by historical, political, and cultural ties as well as the widespread influence of Korean popular culture, has stimulated the expansion of Korean language learning and academic engagement. Through a comprehensive analysis of Korean Studies programs across Taiwanese universities, the study identifies a clear rise in student enrollment and curricular diversification, with course offerings now extending beyond language instruction to encompass interdisciplinary topics such as Korean politics, …

Basic Effectiveness Of Group Mindfulness-Based Cognitive Therapy (Gmbct) In The University Setting, John Robert C. Rilveria, Nisseth Clarize S. Carido, April Veronica G. Lansangan, Alaya Gabrielle N. Villaflor, Anna Cristina A. Tuazon, Divine Love A. Salvador, Violeta V. Bautista

Asia-Pacific Social Science Review

The COVID-19 pandemic has reshaped daily life and amplified mental health challenges worldwide, with university students identified as a particularly vulnerable group. To address this need, the present study evaluated the effectiveness of group mindfulness-based cognitive therapy (GMBCT) as an evidence-based intervention for students receiving psychosocial services during the pandemic. Using a pretest–posttest design, data from 34 students randomly assigned to either GMBCT or individual treatment-as-usual (TAU) provided by a university-based clinic were analyzed. To evaluate treatment effects, an analysis of covariance (ANCOVA) was conducted to compare post-treatment outcomes between the two groups while controlling for pre-treatment scores, treatment length, …

Exploring Societal Development: The Impact Of Social Innovation And Social Entrepreneurship - A Critical Review, Sneh Prabha, Satyaki Sarkar, Supriyo Roy

Asia-Pacific Social Science Review

In recent years, the emergence of social innovations and social entrepreneurship has dramatically influenced societal development. This paper explores the impact of synergizing social innovations and social entrepreneurship on various aspects of society, from economic policy to community resilience and societal development. Through a multidisciplinary lens, the research seeks an extensive review of social innovation and provides new solutions to entrenched social issues, whereas social entrepreneurship transforms these innovations into scalable initiatives that create meaningful change in society. While keeping traditional factors in mind, we explore the role of technology in developing new ways of working, the importance of collaboration …

Isomorphism And Network Governance:A Reflection Of The Thai Elderly Quality Of Life Development And Career Promotion Centers, Ratchaphon Amsuk, Piyamart Tupmongkol, Phengkamon Marnarath, Siriprapa Promma

Asia-Pacific Social Science Review

This study aims to examine isomorphism, network governance, and the spectrum of participation, as classified by the International Association of Public Participation, in the management of the elderly quality of life development and career promotion centers (EQCCs). This study applied the concepts of isomorphism from institutional theory, network governance, and spectrum of participation as defined by the International Association for Public Participation (IAP2), as the instruments for analysis. The findings revealed that EQCCs’ isomorphism emerged before and after the establishment. The three isomorphism mechanisms—coercive, mimetic, and normative—affected the isomorphism of the EQCCs, leading to organization homogenization. However, the management of …

The Dynamics Of The G77, G7, G20, And Brics: Insights And Actions For Enhancing Asean’S Role In Global Economic Governance, Long Yang, Ploypailin Kijkasiwat

Asia-Pacific Social Science Review

In recent decades, the Global North and South have established a number of global economic governance (GEG) clubs, including the Group of 77 (G77), Group of 7 (G7), Group of 20 (G20), and BRICS (Brazil, Russia, India, China, and South Africa) Group, to influence the global economic order. Many sovereign countries and intergovernmental organizations have assumed influential roles in the GEG system by joining these governance platforms as full members. Recognizing ASEAN’s traditionally limited role in the global economic governance system, the authors suggest that ASEAN nations should strengthen their relationships with some of these governance clubs. This article discusses …

Mainstreaming Kautilya In Realism’S Intellectual Tradition: A Top-Down Approach For Global International Relations, Don Mclain Gill

Asia-Pacific Social Science Review

Students of realism often find themselves limited in their appreciation of the paradigm’s dynamic characteristics due to the dominance of mainstream literature, which primarily presents the ideas and views of thinkers from just one part of the world. Although there is nothing wrong with promoting distinguished thinkers from the West whose ideas resonate strongly with contemporary realist analysis, this article seeks to broaden the conversation within realism through the lens of Global International Relations. Although non-Western scholars have recently endeavored to present novel variants of realism that reflected important experiences of the developing world, these bottom-up contributions have often faced …

Sky, Atreyee Majumder

Articles

A peer-reviewed ethnographic poem, it is a reflection on the travel of the soul across time and in and out of bodies, a theory that is well regarded in the corpus of Hindu philosophy. Formally, the poem is an attempt to excavate the skeleton of the Indian poet/scholar/translator A K Ramanujan's poem Chicago Zen.

Roots Of The Human Psyche: The Spiritual Connection Of Nature With The Mind, Dania Hussain Abdulmunem, Nadia Ali Ismael

Alustath Journal for Human and Social Sciences

Seamus Justin Heaney (1939-2013) was intensely engaged in nature in a way that differed from the usual concept of nature representing beauty, love, and romance. Heaney's role in portraying nature is unique. Describing nature from a deeper perspective reveals what nature hides in terms of darkness and violence. This image encourages people to contemplate more deeply because beauty may conceal a lot of sadness and grief. The poet intends to reflect on the events of the conflicts in Ireland and around the world through nature. Just as nature conceals darkness, so does the individual conceal the inner meaning of his …

The Jurisprudential Opinions Of Al-Sabzwari In His Book Muhadhdhab Al-Ahkam The Issue Of Resting In Prayer As An Example (A Comparative Study) Research Extracted From A Doctoral Thesis, Narges Mahdi Saghir Mohsen, Aqeel Razzaq Noaman

Alustath Journal for Human and Social Sciences

Sayyed Abd al-A’la al-Sabuzari is considered one of the leading contemporary Imami jurists, and his book Muhadhdhab al-Ahkam is one of the most prominent books of contemporary Imami jurisprudence. In these research papers, we have intended to study the issue of resting in prayer according to Sayyid al-Sabzwari as a comparative study, and the most prominent results that this study has yielded are that scholars They differed on this issue into four opinions, and it has been proven that the most correct opinion is what was preferred by Mr. Al-Sabzwari, which is the opinion of those who hold the first …

Lattice Thermal Transport Beyond The Quasiparticle Approximation: Nontrivial Spectral Competition Between Three- And Four-Phonon Interactions, Yi Xia

Mechanical and Materials Engineering Faculty Publications and Presentations

The breakdown of the quasiparticle approximation (QPA) for phonons in strongly anharmonic materials necessitates advanced first-principles frameworks for accurate lattice dynamics and thermal transport predictions. We develop a comprehensive beyond-quasiparticle approximation (BQPA) approach incorporating both three- (3ph) and four-phonon (4ph) interactions and apply it to investigate lattice thermal conductivity (κL) in MgO, PbTe, and AgCl – materials that span a broad spectrum of anharmonicity, from weak to severe anharmonic regimes with overdamped phonons. We reveal that while BQPA consistently increases κL relative to QPA due to phonon softening when considering only 3ph interactions, the inclusion of additional 4ph interactions hardens …

Leveraging Social Capital For Value Creation In Public Procurement: The Role Of Strategic Purchasing Integration, Iryna Malacina, Jad El Bizri, Frederik G. S. Vos, Elina Karttunen, Aki Jaaskelainen

Business Faculty Publications and Presentations

Purpose Although the integration of the purchasing function within strategic decision-making has been extensively studied in the context of the private sector, its significance for the effective functioning of public procurement (PP) remains underexplored. Effective PP is critical for suppliers, users of public services and society at large. This study investigates how the strategic integration of PP influences operational, environmental and innovative value creation by developing social capital in buyer–supplier relationships. Design/methodology/approach This study empirically examined how strategic purchasing integration contributes to the development of social capital in buyer–supplier relationships, which in turn affects value creation. It utilizes survey data …

Elucidating The Role Of Pbaf Chromatin Remodeling Subunit Arid2 In B Cell Development, Rachel Paolini

Arts & Sciences Graduate Student Theses and Dissertations

B cells are key components of the adaptive immune system that mediate humoral immunity through the production of antigen-specific antibodies. The generation of functional B cells involves multiple stages of differentiation across distinct anatomical niches, requiring precise regulation of microenvironmental signals and intrinsic transcriptional networks. SWI/SNF chromatin remodeling complexes have emerged as key regulators of B cell lineage commitment by modulating the accessibility of transcriptional programs required for differentiation and maturation. However, the specific roles of individual SWI/SNF subunits and distinct complexes within early B cell differentiation remain poorly understood. In this thesis, I investigated the function of Arid2, an …

The Double Patenting Puzzle, Michael Risch

Faculty Publications

It’s a simple rule: one patent per invention. This is easy to enforce when patent claims in two patents are identical, but what if the second patent claims something close but not quite the same? For more than 150 years, courts have held that obvious improvements over the prior art cannot be patented. But when inventors seek a small improvement in their own follow-on patents, there may not be any prior art because the law does not typically count inventors’ work against themselves. Inventors can include two similar claims in the same patent without objection, but if they split them …

Enhancing Exercise Engagement And Gait In Parkinson Disease: Participation Factors, Novel Approaches, And The Role Of Rhythmic Auditory Cueing, Allison Haussler

WUSM Theses and Dissertations – All Programs

Parkinson disease (PD) is the second most common neurodegenerative disease, characterized by gait and balance impairments that reduce independence and diminish quality of life. Exercise and other rehabilitation strategies, such as rhythmic auditory cueing, are well-researched methods to address motor impairments. However, despite the strong body of research supporting these approaches, many individuals with PD remain sedentary and do not meet current exercise recommendations. This highlights a critical gap between evidence and real-world behavior.

While prior research identified general motivators and barriers to exercise in people with PD, emerging exercise modalities and the growing diversity of community-based programs emphasize the …