Digital Commons Network^™

Repurposing Diclofenac For Combination Therapy: Targeting The Warburg Effect To Enhance Breast Cancer Treatment ​, Gonca Tuna, Eli̇f Ertürk, Ayşen Sağnak, Ferda Ari

Turkish Journal of Medical Sciences

Background/aim: Diclofenac (Diclo), a widely used nonsteroidal antiinflammatory drug, has emerged as a potential candidate for drug repurposing in oncology, with reported anticancer effects extending beyond cyclooxygenase (COX) inhibition, including modulation of tumor metabolism. This study investigated the antiproliferative and glycolysis-associated effects of Diclo in MCF-7 breast cancer cells, alone and in combination with docetaxel (Doc) or 5-fluorouracil (5-FU).

Materials and methods: Cell viability was assessed using the sulforhodamine B (SRB) assay. To evaluate metabolic alterations, glucose uptake and lactate release were quantified following treatment. In addition, Triosephosphate Isomerase (TPI) protein levels and Lactate Dehydrogenase (LDH) activity were measured to …

Antiobesity, Antidiabetic, And Antioxidant Activities Of Selected Rubia Species (Rubiaceae) And Lc–Ms/Ms-Based Chemical Profiling ​, Semi̇h Bulut, Ahmet Kahraman, Ayşenur Işik, Mustafa Abdullah Yilmaz

Turkish Journal of Medical Sciences

Background/aim: Rubia species (Rubiaceae) are recognized as medicinal and industrial plants exhibiting diverse biological activities. This study was conducted to evaluate the antioxidant, antidiabetic, and antiobesity potential of extracts prepared from Rubia davisiana Ehrend. (an endemic species), R. peregrina L., and R. rotundifolia Banks & Sol., which grow naturally in Türkiye.

Materials and methods: The antioxidant activity of 80% ethanol extracts prepared from the aerial parts was evaluated using 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays, ferric reducing power, metal chelating capacity, and total antioxidant capacity assays. Inhibition assays for α-glucosidase and α-amylase were performed to evaluate antidiabetic activity, …

Cervical Conjoined Nerve Root Anomalies: Prevalence And Impact On Posterior Cervical Surgery, Ahmet Eren Seçen, Ayfer Aslan, Musa Onur Özbakir, Uğur Kemal Gündüz, Ali̇ Dalgiç

Turkish Journal of Medical Sciences

Background/aim: Anomalous nerve roots (ANRs) are well described in the lumbosacral spine but are rarely reported in the cervical region. The aim of this study was to evaluate the incidence, clinical characteristics, and surgical outcomes of cervical ANRs, with particular emphasis on conjoined nerve roots, in a single-center clinical series.

Materials and methods: A retrospective analysis was conducted of patients who underwent posterior cervical discectomy for cervical disc herniation at our institution between 2010 and 2025. A total of 113 posterior cervical procedures were performed, and seven patients were found to have surgically confirmed cervical ANRs. For these patients, demographic …

Preserved Inflammatory Homeostasis During Emergency Transport: A Multibiomarker Assessment Of Neonatal Rds Transfers ​, Eyüp Sari, Şeri̇fe Suna Oğuz, Mehmet Semi̇h Demi̇rtaş, Bensu Bulut, Medi̇ne Akkan Öz, Murat Genç, Ayşenur Gür, Ümi̇t Alper Özcan, Hüseyi̇n Mutlu, Rami̇z Yazici

Turkish Journal of Medical Sciences

Background/aim: The aim was to compare the pre- and posttransport levels of systemic inflammatory markers in neonatal infants transported to a tertiary intensive care unit via emergency health services with a neonatal respiratory distress syndrome (nRDS) diagnosis and to assess the quality of transport.

Materials and methods: This retrospective study was conducted between January 2019 and December 2023. A total of 117 nRDS patients’ emergency transports were included in the study. Demographic data, transfer time, intubation, cold treatment, cardiopulmonary resuscitation (CPR), and pre- and posttransport laboratory parameters were obtained retrospectively. The statistical analysis was performed using IBM SPSS Statistics (Version …

Face Mask Littering: Environmental Impacts, Regulatory Challenges, And Ai-Driven Waste Management Strategies For The Post-Pandemic Era, Pri̇yanka Rathee, Sari̇ta Khatkar, Renu Sehrawat, Pooja Rathee, Anurag Khatkar, Esra Küpeli̇

Turkish Journal of Medical Sciences

The widespread use of polypropylene-based face masks during the COVID-19 pandemic created a significant and persistent source of plastic pollution. This review aims to provide an integrative assessment of the environmental, toxicological, and public health implications of face mask litter and evaluate current waste management challenges and emerging technological solutions in the postpandemic context. A narrative review approach was employed, synthesizing literature published between 2020 and 2025 and indexed in major scientific databases including Web of Science, Scopus, and PubMed. Studies were selected based on their relevance to the issues of environmental contamination, microplastic generation, toxicological effects, regulatory frameworks, and …

Posttraumatic Stress In Newly Diagnosed Epilepsy: Associations With Early Maladaptive Schemas, Anxiety, And Quality Of Life In A 6-Month Prospective Study ​, Mehmet Öztürk, Pinar Öztürk, Fügen Sönmez Çeti̇nkaya, İlker Özdemi̇r

Turkish Journal of Medical Sciences

Background/aim: Epilepsy is a chronic neurological disorder that significantly affects psychosocial functioning, self-perception, and quality of life. Emerging evidence suggests that posttraumatic stress (PTS) symptoms may be more prevalent in individuals with epilepsy than previously recognized, particularly following seizure-related experiences perceived as traumatic. The aim of this study was to evaluate short- and long-term PTS levels in individuals with newly diagnosed epilepsy and examine their associations with anxiety, depression, early maladaptive schemas, and quality of life.

Materials and methods: In this prospective study, 31 individuals with newly diagnosed epilepsy were enrolled. Participants completed a sociodemographic data form, the Post-Traumatic Stress …

Influenza, Covid-19, And Pneumococcal Vaccination Status Among Adults In Türkiye ​, Gamze Şanlidağ İşbi̇len, Serap Gençer, Hüsnü Pullukçu, Meltem Taşbakan, İftahar Köksal

Turkish Journal of Medical Sciences

Background/aim: Vaccines reduce morbidity and mortality caused by infectious diseases that threaten public health. Lifelong immunization programs are essential for the entire population. This study assessed adult vaccination uptake for influenza, pneumococcal, and coronavirus disease 2019 (COVID-19) vaccines in Türkiye and examined the barriers and factors influencing vaccination decisions.

Materials and methods: This cross-sectional survey was designed and conducted by the Immunization Working Group of the Turkish Society of Clinical Microbiology and Infectious Diseases. A 19-item questionnaire was administered to individuals aged 18 years or older to assess influenza, pneumococcal, and COVID-19 vaccination status. The questionnaire collected data on demographic …

Nationwide Characteristics Of Infectious Disease Patients Transported By Helicopter In Türkiye, Ayşe Gülden Bekgöz, Kerem Dost Bi̇lmez, Muhammed Saltuk Deni̇z

Turkish Journal of Medical Sciences

Background/aim: To evaluate the clinical, demographic, and operational characteristics of patients with infectious diseases transported by helicopter ambulance and to examine differences in the transfer patterns, flight durations, and diagnostic categories.

Materials and methods: Registry data of patients with infectious diseases transported by helicopter ambulance were analyzed. Demographic characteristics, diagnoses, referring and receiving hospital types, intraprovincial and interprovincial transfer status, flight durations, and temporal distribution of transfers (hours, days, and months) were evaluated. Flight duration was calculated in minutes and compared between intraprovincial and interprovincial transfers.

Results: A total of 543 patients with infectious diseases were transported by helicopter ambulance. …

Ethical Principles For Employing Artificial Intelligence In Media Coverage Of The 2023–2024 Al-Aqsa Flood Operation, Safa Mazhoud Sari Alabrawi, Salma Mazhoud Sari Alabrawi

Journal of Arts and Social Sciences

This study aims to investigate the ethical principles governing the use of artificial intelligence in media coverage, using the 2023-2024 Gaza war as a case study to identify these principles. The study drew on Political Marketing Theory and Gatekeeping Theory. Several research tools were employed, including Content analysis of Al Arabiya’s website (alarabiya. net) over a three-month period documentary analysis of four AI guides and a review of the relevant literature, previous research and studies. The study revealed several results, the most important of which is the great convergence between the ethical principles of media coverage--namely responsibility, freedom, independence, credibility …

Crisis Communication Management During Covid 19 In The Sultanate Of Oman: An Analytical Study Of The Government Communication Center’S Accounts On X Platform, Aaisha Alkaabi, Faten Ben Lagha

Journal of Arts and Social Sciences

This study examines the characteristics of the content published on the Omani Government Communication Center’s accounts on X platform, namely its official account and its “Oman VS Covid 19” account, which was dedicated to managing the COVID-19 crisis during the period from January 2020 to August 2022. The study adopted Betteke Van Ruler’s Communication Grid of Tactics Model and employed the survey method to achieve its objectives through two research tools: content analysis tools and semi-structured interviews. The findings revealed a diversity of media formats used in the posts published by the two accounts (text with infographics, images, and videos), …

Byron Fullerton Papers, 1939-1954, Byron Fullerton

Center for Restoration Studies Archives, Manuscripts and Personal Papers Finding Aids

No abstract provided.

Scattering Phase Shift In Quantum Mechanics On Quantum Computers: Non-Hermitian Systems And Imaginary-Time Simulations, Peng Guo, Paul Levan, Frank Lee, Yong Zhao

Research & Publications

To overcome the fast oscillatory behavior of correlation functions for extracting scattering phase shift in real-time quantum simulations encountered in the work of Guo et al. [Phys. Rev. D 113, 054512 (2026)], we propose and test two solutions in the present work. One is to simulate Hermitian systems in imaginary time, and the other is to simulate non-Hermitian systems in real time. We demonstrate that both approaches lead to the problem of nonunitary quantum evolution that can be solved by combining two quantum algorithms: block encoding and Hadamard test. The combined quantum algorithm does not require midcircuit …

The Current - Volume 37 Issue 01, Nova Southeastern University

Student Newspapers

No abstract provided.

Conservation As A Guise: Green Grabbing And The Acculturation Erasure In Rempang, Indonesia, Umi Ma'rufah, Bobi Bobi, Yogi Eka Sahputra, Muhammad Ishlahudin

Forest and Society

This study examines how the state enacts green grabbing through forestry legal instruments and how this process intersects with the existence and cultural acculturation of the Sungai Raya community. Previous studies on state-led green grabbing have predominantly emphasized economic, political, and ecological dimensions, often overlooking the socio-cultural dynamics of affected communities. Employing a qualitative narrative research approach, this study draws on in-depth interviews and literature review to reconstruct the life histories of community members. Using the Rempang Eco-City National Strategic Project as a case study, this research identifies the unilateral designation of Kawasan Hutan Taman Buru (the Hunting Park Forest …

Ancestors And Tiger From Elsewhere: Emerging Forms Of Human-Tiger Socio-Natural Relations In Cosmopolitical Frontiers Of Sumatra, Imam Ardhianto, Febri Sastiviani Putri Cantika, Matahari Jingga, Dimas Iqbal Romadhon

Forest and Society

How are the moral relations between communities and the Sumatran tiger (Panthera tigris sumatrae) being reconfigured as forests fragment and land-use change accelerates across Sumatra's conservation landscape? This article addresses that question ethnographically, drawing on forty semi-structured interviews conducted in Agam and Pasaman Regencies (West Sumatra) between April and June 2026 and interviews with Yayasan SINTAS Indonesia. The article documents the three animistic category of the tiger, comprising Datuk/ancestor, harimau jadi-jadian, and harimau tandang, and traces how it is being reshaped by habitat fragmentation, commodity-driven land expansion, generational interruption of customary authority, and state translocation …

Unpacking System Factors Contributing To Delayed Icu Discharges: A Mixed-Method Study, Xia Jin, Anne Mette Nørby Adams, Joanne Mcintyre, Steven Galluccio, Shailesh Bihari, Ubbo F. Wiersema, Kathrine De Lyster, Frances Fengzhi Lin

International Nursing Research Congress (INRC)

Background: Discharge delay in resource-constrained Intensive Care Units (ICUs) remains a concerning and persistent challenge, resulting in delayed ICU admissions and after-hours discharges. These delays are associated with adverse patient outcomes and system inefficiency. While centralised patient flow centres and other strategies have been implemented to address these issues, their impact on ICU discharge delays remains unexplored. To improve patient flow, it is essential to explore organisational barriers and facilitators to ICU discharge.

Objective: To identify system factors influencing ICU discharge in a tertiary Australian hospital.

Methods: A mixed-method study was conducted in a 32-bed tertiary ICU in Australia. Between …

Treaty Hierarchy And Legal Pluralism In Cross-Border Governance: Comparative Study Of Jordan And France, Rola Nael Salameh, Numan Ahmad Elkhatib, Rami Ali Daradkeh, Mohammad Sulieman Issa Alhelalat

Hasanuddin Law Review

This study addresses the constitutional ambiguity surrounding the hierarchical status and domestic application of international human rights treaties, particularly in legal systems where treaty incorporation lacks explicit constitutional regulation. Though earlier researches have discussed issues such as treaty incorporation and constitutionality, there has been little analysis of the comparative role played by courts in bridging the international and domestic legal systems. The study adopts a qualitative doctrinal and comparative legal methodology, analyzing constitutional provisions, legislative frameworks, and judicial decisions across Jordan, France, and selected Arab jurisdictions, including Egypt and Morocco. The findings reveal that France adopts a hierarchical model granting …

Bc-Xaia: A Blockchain-Based Recruitment Framework With Explainable Ai And Smart Contract Integration, Heba Allah Adel, Sayed Abdelgaber, Wessam H. El-Behaidy

Computer Science

Ensuring transparency and security in digital recruitment systems remains a critical challenge. This study proposes BC-XAIA, a unified framework that integrates blockchain, smart contracts, explainable artificial intelligence (XAI), and agile methodology to enable consistent, secure, and traceable recruitment decision-making. Smart contracts, implemented in Solidity and deployed using the Remix Ethereum IDE, automate key processes such as identity verification, data access control, and behavior monitoring, reducing reliance on centralized intermediaries. To support intelligent decision-making, multiple machine learning models, including Random Forest, Logistic Regression, and Support Vector Machine (SVM), were trained and evaluated on a recruitment dataset, with Random Forest achieving the …

Motherhood-Defining Memories And Narrative Identity Awareness In Relation To Psychological Wellbeing And Maternal Functioning Following A Parenting Program, Christin Camia, Antje Von Suchodoletz, Michelle P. Kelly

All Works

Introduction – Drawing on previous research showing that self- and relationship-defining memories relate to psychological and relational functioning, this study began to explore motherhood-defining memories and their relation to psychological wellbeing and maternal functioning within a parenting program context. The study aimed to examine whether participation contributes to the narrative coherence of motherhood-defining memories. Methods – Participants were 155 mothers from diverse cultural backgrounds (M age = 32.85 years, SD age = 5.20) residing in the United Arab Emirates (UAE). Seventy-five mothers participated in an eight-session parenting program, and 80 mothers served as controls in a comparison group. Motherhood-defining memories …

Rethinking Education For Sustainable Development: The Role Of Blended Learning Within Skill-Based Higher Education, Nessrin Shaya, Sandra Baroudi, Serena Aoun, Rawan Abukhait

All Works

Purpose – Drawing on Social Cognitive Career Theory, this study positions blended learning not merely as a technological enhancement but as a strategic pedagogical mechanism for operationalizing sustainable development. It examines how blended learning within interdisciplinary and skill-based higher education environments cultivate employability skills that support sustainable educational practices. Design/methodology/approach – The study adopts a survey design. Where data were collected from 782 undergraduate students across five universities in UAE. Two institutions offered blended, interdisciplinary and skill-based courses, while three delivered the same courses through traditional face-to-face formats. The structural model was examined using structural equation modeling (SEM) with bootstrapping …

Definitive Radiation Therapy For Schneiderian Inverted Papilloma Of The Soft Palate And Uvula., Rahul Sinha, Arianne J Abreu, Christopher E Fundakowski, Robert T Sataloff

Otolaryngology (ENT) Resident Research

Schneiderian inverted papilloma is a benign, locally aggressive tumor that typically arises in the respiratory mucosa of the nasal cavity and paranasal sinuses. These tumors are often asymptomatic but can cause unilateral nasal obstruction, discharge, hyposmia and epistaxis. They warrant attention particularly due to the potential for malignant transformation. They are treated most often with surgical excision. This case report describes a patient with Schneiderian inverted papilloma arising outside its usual location and managed with definitive radiation therapy instead of surgical excision due to concerns for functional impairment. Remission was obtained with radiation therapy, although the patient experienced treatment-related side …

Cover And Contents

Turkish Journal of Agriculture and Forestry

No abstract provided.

Crispr-Cas9: An Emerging And Precise Genome Editing System For Crops To Combat Food Insecurity, Muhammad Faran Tahi̇r, Muhammad Hamzah Saleem, Sidra Aslam, Emi̇ne Orhan, Hayat Topçu, Tauqeer Ahmed Qadri, Khalid Ali Khan, Muhammad Anas

Turkish Journal of Agriculture and Forestry

Genome editing has emerged as a transformative tool to improve crop productivity, resilience, and nutritional quality, helping address global food insecurity. Among gene-editing platforms, clustered regularly interspaced short palindromic repeats (CRISPR)/ Cas systems (notably CRISPR-Cas9) offer simple, efficient, and scalable methods for targeted modifications, including knockouts, base edits, and precise “search-and-replace” prime edits. In plants, recent advances such as improved base editors, optimized prime-editing platforms, and DNA-free delivery methods have expanded the scope of edits achievable while reducing off-target effects and regulatory concerns. This review summarizes CRISPR principles, highlights technical breakthroughs and crop applications that mitigate biotic and abiotic stresses, …

Enhancing Salinity Tolerance In Phyla Nodiflora L. With Potassium Humate: Crosstalk Between Osmolytes, Antioxidants, And Mineral Uptake, Fatemeh Sadeghi, Somayeh Esmaeili, Mehrangiz Chehrazi

Turkish Journal of Agriculture and Forestry

Salinity stress impairs plant growth, nutrient homeostasis, and metabolism, particularly in arid ecosystems. Phyla nodiflora, a ground cover used for erosion control, shows preliminary salinity tolerance, but the mechanistic basis of its long-term adaptation and the potential for enhancement via potassium humate (KH) were unknown. Plant growth, key biochemical attributes, and nutrient uptake were assessed to elucidate how KH modulates physiological performance under increasing salinity. In a 129-day greenhouse experiment, plants were exposed to five salinity levels (0 to 16 dS m⁻¹ NaCl) and three KH concentrations (0, 500, and 1000 mg L⁻¹). Severe salinity (16 dS m⁻¹) without KH …

Distribution And Seasonal Prevalence Of Nosema Maddoxi (Microsporidia: Nosematidae) In The Brown Marmorated Stink Bug, Halyomorpha Halys (Hemiptera: Pentatomidae) Populations In Türkiye, Ömer Ertürk, Samet Eker, Mustafa Yaman, Gönül Algi

Turkish Journal of Agriculture and Forestry

The brown marmorated stink bug, Halyomorpha halys feeds on a wide range of crops and causes major economic losses. With its high flight capacity, H. halys is an invasive species that damages many crops worldwide. By elucidating the activity, distribution, and prevalence of the microsporidian pathogen Nosema maddoxi, the damage and economic losses caused by H. halys can be reduced. This study aimed to assess the distribution and seasonal prevalence of N. maddoxi in H. halys populations distributed throughout hazelnut fields the Eastern Black Sea Region of Türkiye. H. halys adults were collected and examined in detail under the microscope …

Cultivar, Canopy Architecture, And Harvest Stage Shape The Chemical Profile Of Plum (Prunus Domestica) Fruit, Jelisaveta Seka Cvijanović, Milica Sredojević, Dragana Dabić Zagorac, Maja Natić, Geza Bujdoso, Miljan Cvetković

Turkish Journal of Agriculture and Forestry

Plum (Prunus domestica L.) is a nutritionally valuable fruit with significant commercial importance, yet consumer acceptance is often constrained by inconsistent fruit quality. This study investigated the effects of cultivar, training system, and harvest stage on the chemical composition of plum fruit, focusing on polyphenols, organic acids, sugars, and sugar alcohols. Three cultivars (Čačanska lepotica, Stanley, and Empress) were evaluated under different canopy architectures, including plum spindle as a control and novel 2-dimensional systems (Bi axe and upright fruiting offshoot), across multiple ripening stages. The results showed that genotype and canopy structure significantly influenced the accumulation of primary and secondary …

Genetic Algorithm For Agricultural Logistics Optimization: Solving The Capacitated Vehicle Routing Problem In Rural Distribution, Min Song, Kan Lu

Turkish Journal of Agriculture and Forestry

With the rapid advancement of agricultural modernization and the increasing demand for agricultural products, inefficient logistics distribution has become a major bottleneck in rural supply chains. This study addresses the capacitated vehicle routing problem (CVRP) in agricultural logistics. A genetic algorithm (GA)-based optimization model was proposed to enhance distribution efficiency. The model integrates critical agricultural characteristics, including multidistribution center networks, seasonal delivery schedules, and regional road infrastructure constraints, to minimize both transportation distance and operational costs. Experimental results show that the GA outperforms traditional metaheuristic methods (e.g., particle swarm optimization and simulated annealing), achieving a >5 km reduction in total …

Genetic Diversity And Population Structure Of Carob Germplasm From Lebanon, Morocco, And Spain Reveal Potential For Innovative Breeding Programs, Mohamad Ali El Chami, Guillermo Palacios-Rodriguez, Rafael Maria Navarro-Cerrillo, Lamis Chalak, Maria Dolores-Rey

Turkish Journal of Agriculture and Forestry

The carob tree (Ceratonia siliqua L.) is a drought-tolerant species native to the Mediterranean Basin. It has been cultivated for centuries for its highly nutritious, edible pods. Genetic diversity is one of the key requirements for the effective management and utilization of plant genetic resources. In this study, we evaluated the genetic diversity and population structure of 169 seminatural carob individuals from Lebanon, Spain, and Morocco using nine expressed sequence tag-simple sequence repeat (EST-SSR) markers. A total of eight polymorphic EST-SSR loci produced 43 alleles, with Cesi_187 and Cesi_1187 identified as the most informative markers. Results of AMOVA and SAMOVA …

Beyond Closed Doors: Standardizing Intimate Partner Violence Screening In A Predominantly Spanish-Speaking Primary Care Clinic, Sarah Abughrib

Master's Projects and Capstones

Objective: Intimate partner violence is a widespread public health concern, with an estimated 64.2 million U.S. adults affected in their lifetime and significant physical, psychological, and economic consequences. Due to systemic challenges, IPV screening remained inconsistent across an adult primary care clinic serving a predominantly monolingual Spanish-speaking population in the San Francisco Bay Area, with only 4.1% of patients screened across the Adult, Women's, and Teen clinics in June 2026. Aim: This quality improvement project aimed to increase overall IPV screening by 10%, from 4.1% to 14.1%, by July 31, 2026. Methods: Standardization efforts included introducing a …

Staff Education To Improve Hand Hygiene And Personal Protective Equipment Compliance, Suliat Oluwa

Walden Dissertations and Doctoral Studies

This doctoral project is a staff education initiative designed to strengthen hand hygiene and personal protective equipment (PPE) practices among interdisciplinary staff in a long-term care (LTC) facility. The practice problem addressed inconsistent hand hygiene and PPE use across shifts and departments, contributing to healthcare-associated infections (HAIs). Because LTC residents are highly vulnerable due to advanced age, multiple comorbidities, and shared living environments, improving adherence to infection prevention practices is essential for enhancing resident safety, reducing preventable infections, and supporting compliance with Centers for Disease Control and Prevention (CDC) and Centers for Medicare & Medicaid Services (CMS) infection prevention standards. …