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Teachers’ Perceptions Of Employer-Provided Afterschool Childcare As A Retention Strategy: A Herzberg-Informed Qualitative Case Study, Lakinsha R. Swinton Dec 2025

Teachers’ Perceptions Of Employer-Provided Afterschool Childcare As A Retention Strategy: A Herzberg-Informed Qualitative Case Study, Lakinsha R. Swinton

Walden Dissertations and Doctoral Studies

Teacher retention has been a growing issue, as the rate of teacher vacancies has continued to increase after the COVID-19 pandemic. The increase in teacher vacancies after the pandemic highlighted the importance of retaining and attracting highly qualified teachers for schools and school districts. A coastal South Carolina school district had been providing employee support services to retain current staff and create a competitive advantage over other school districts in attracting new staff. The purpose of this generic qualitative study is to examine the perception of classroom teachers regarding the efficacy of free afterschool childcare as an employee support service …


Academic Standards Subcommittee Agenda December 18, 2025, Utah State University Dec 2025

Academic Standards Subcommittee Agenda December 18, 2025, Utah State University

Educational Policies Committee

  • Welcome and approval of November 20, 2025 minutes
  • New Topics:
  • Proposal for Academic Grievance Policy rewrite
  • Proposal to add Bachelor of Applied Sciences (BAS) academic degree requirements
  • Information item: Attendance and Excused Absences policy clarification


A Comprehensive Review Of Dental Diseases Detection And Classification Based On Artificial Intelligence Techniques, Nermeen N. Noaman, Yasmin M. Alsakar, Naira E. Elazab, Waleed M. Mohamed, Mohamed E. Ezzat, Mohammed M. Elmogy Dec 2025

A Comprehensive Review Of Dental Diseases Detection And Classification Based On Artificial Intelligence Techniques, Nermeen N. Noaman, Yasmin M. Alsakar, Naira E. Elazab, Waleed M. Mohamed, Mohamed E. Ezzat, Mohammed M. Elmogy

Mansoura Engineering Journal

In dentistry, many diseases, such as gum, cavities, and oral cancer, affect people of all ages. Early treatment and diagnosis are crucial for minimizing dental diseases' effect on overall health and saving money in the long run. Traditional dental diagnosis methods, such as manual probing and visual inspection, are time-consuming and can be subject to human errors. Hence, a computer-aided diagnosis system based on computer vision and artificial intelligence (AI) techniques is needed. The considerable progress in computer vision and AI techniques offers many possibilities in dental diagnosis based on dental X-ray imaging modalities. Dental X-rays are used to diagnose …


Geolocation Algorithms And On-Orbit Calibration For Atmospheric Waves Experiment, Eric Mckinney, Keith Blonquist, Zack Hatfield, Connor Waite, Brooke Wursten, Pedro Sevilla, Ludger Scherliess, Harri Latvakoski, Greg Cantwell Dec 2025

Geolocation Algorithms And On-Orbit Calibration For Atmospheric Waves Experiment, Eric Mckinney, Keith Blonquist, Zack Hatfield, Connor Waite, Brooke Wursten, Pedro Sevilla, Ludger Scherliess, Harri Latvakoski, Greg Cantwell

Space Dynamics Laboratory Publications

1 - Overview

  • Motivation: Atmospheric gravity waves can degrade navigation, tracking, communications, and geolocation system signals. They can also affect satellite/debris orbit and reentry predictions.
  • NASA's Atmospheric Waves Experiment (AWE) is currently on ISS measuring atmospheric gravity waves in the OH airglow layer at ~87 km altitude
  • Impact: Improved space weather understanding, estimation, and forecasting


Book Review: Code Name Puritan: Norman Holmes Pearson At The Nexus Of Poetry, Espionage, And American Power, Wylie W. Johnson Dec 2025

Book Review: Code Name Puritan: Norman Holmes Pearson At The Nexus Of Poetry, Espionage, And American Power, Wylie W. Johnson

Parameters Bookshelf – Online Book Reviews

Author: Greg Barnhisel

Reviewed by: Wylie W. Johnson

In this riveting biography, Greg Barnhisel uncovers the extraordinary life of Norman Holmes Pearson—a Yale professor, literary tastemaker, and covert intelligence officer. Seamlessly blending poetry, espionage, and Cold War politics, Code Name Puritan reveals how Pearson helped shape both American cultural identity and national security strategy. From championing modernist women poets to dismantling Nazi spy networks, Pearson’s story is a fascinating portrait of influence at the intersection of intellect and power.

©2025 Wylie W. Johnson


Book Review: Men Of God, Men Of War: Military Chaplains As Ministers, Warriors, And Prisoners, Geoff Bailey Dec 2025

Book Review: Men Of God, Men Of War: Military Chaplains As Ministers, Warriors, And Prisoners, Geoff Bailey

Parameters Bookshelf – Online Book Reviews

Author: Robert C. Doyle

Reviewed by: Chaplain (Colonel) Geoff Bailey, PhD, US Army War College chaplain and director of ethical development, Department of Command, Leadership, and Management, US Army War College

Robert C. Doyle offers a sweeping historical study of chaplains in American wars, revealing how faith and duty intersected on battlefields and in prison camps.


Omics Approaches To Understand Cardiovascular Disease, Zeeshan Ahmed, Goo Jun Dec 2025

Omics Approaches To Understand Cardiovascular Disease, Zeeshan Ahmed, Goo Jun

Faculty, Staff and Student Publications

Omics approaches have emerged as indispensable tools in unravelling the intricate molecular landscape of cardiovascular disease (CVD) by providing comprehensive insights into the underlying mechanisms driving CVD pathogenesis, progression, and response to therapy. Integrative omics approaches further enhance our understanding by integrating multi-omics data to explain complex molecular networks and identify novel disease pathways. In this collection of BMC Cardiovascular Disorders, we invited submissions on omics approaches to investigate and understand CVD. Successfully achieving the goals of this collection, we were able to publish some interesting and impactful research articles after a rigorous peer review process.


Chronic Absenteeism: A Case Study In A Central Virginia High School Investigating Student Habits And Potential Interventions, Ronald R. Proffitt Dec 2025

Chronic Absenteeism: A Case Study In A Central Virginia High School Investigating Student Habits And Potential Interventions, Ronald R. Proffitt

Graduate Dissertations and Theses

Abstract

The purpose of this single case study was to discover and determine the contributing factors for chronic absenteeism for high school students at a rural Central Virginia high school in order to discover potential solutions to increase attendance and to combat chronic absenteeism. An additional factor considered was habits that may have formed during the COVID-19 pandemic, which may have led to an increase in chronic absenteeism rates. The theory that guided this study was Bronfenbrenner’s (1979) Ecological Systems Theory, as it directly addressed how a child relates and reacts to their environments based upon their interactions. The participants …


Transposable Element-Derived Mir-28-5p And Mir-708-5p: Exploring Potential Roles In Lung Cancer, Sergiu Chira, Cornelia Braicu, Stefan Strilciuc, George A Calin, Ioana Berindan-Neagoe Dec 2025

Transposable Element-Derived Mir-28-5p And Mir-708-5p: Exploring Potential Roles In Lung Cancer, Sergiu Chira, Cornelia Braicu, Stefan Strilciuc, George A Calin, Ioana Berindan-Neagoe

Faculty, Staff and Student Publications

Background: Transposable elements are normally silenced by epigenetic mechanisms; however, during malignant transformation, epigenetic alterations enable transposons to produce functional molecules like miRNAs. Among these, LINE-2 (L2) elements can generate miRNAs capable of regulating key genes, including tumor suppressors. Two L2-derived miRNAs, miR-28 and miR-708, have been linked to lung cancer, yet the mechanisms underlying their dysregulation remain poorly understood. Our study reveals how genomic context contributes to aberrant gene expression through comprehensive bioinformatic analyses.

Methods: Using bioinformatics analysis, we evaluated the expression of miR-28 and miR-708 in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) datasets from TCGA. …


Book Review: Disputed Decisions Of World War Ii: Decision Science And Game Theory Perspectives, James Allen Knechtmann Dec 2025

Book Review: Disputed Decisions Of World War Ii: Decision Science And Game Theory Perspectives, James Allen Knechtmann

Parameters Bookshelf – Online Book Reviews

Author: Mark Thompson

Reviewed by: James Allen Knechtmann, supervisory archivist, chief, Ridgway Library Branch, Army Heritage and Education Center, US Army War College

In this innovative analysis of World War II, Thompson applies decision science and game theory to reexamine some of the conflict’s most controversial strategic choices. By modeling the logic behind pivotal decisions, he challenges conventional narratives and reveals the complexity of wartime leadership. This book offers a fresh lens for historians, strategists, and analysts seeking deeper insight into the calculus of war.


Workplace Dignity Amongst Clinical Nurses, Jennifer De Beer, Hawazen Rawas, Wadea Beheri Dec 2025

Workplace Dignity Amongst Clinical Nurses, Jennifer De Beer, Hawazen Rawas, Wadea Beheri

Individual Articles

Background: The workplace environment plays a pivotal role in employees’ lives as they spend many hours there. Recently, greater attention has been placed on workplace conditions as a key social determinant of health. One way through which workplace conditions may affect health is workplace dignity. This study aimed to describe clinical nurses’ workplace dignity.

Methods: The study design was descriptive and cross-sectional. Clinical nurses within a tertiary institution were randomly sampled. Data collection included the Workplace Dignity scale which is an 18 item-seven-point Likert scale consisting of dignity and indignity questions (α.98, and 0.95, respectively). Data collection commenced with a …


Clinical Nurses' Perceived Educational Value Of Nursing Journal Clubs, Jennifer De Beer, Elham Alsanea, Joynalyn Barrios, Shahd Brnawi, Wejdan Barayan, Wadea Beheri, Emily Lenore Heaphy Dec 2025

Clinical Nurses' Perceived Educational Value Of Nursing Journal Clubs, Jennifer De Beer, Elham Alsanea, Joynalyn Barrios, Shahd Brnawi, Wejdan Barayan, Wadea Beheri, Emily Lenore Heaphy

Individual Articles

Background: Evidence-based practice plays a pivotal role in modern nursing decision-making. Healthcare organizations must ensure that nurses consistently have access to and apply the most current evidence. The journal club is a key method for evidence-based education among healthcare professionals. The study aimed to evaluate the perceived educational value of journal clubs among clinical nurses.

Methods: The study used a cross-sectional descriptive survey approach. The setting included a large tertiary hospital in the western region of Saudi Arabia. A total of 208 nurses (mean age 38.9 ± 9.1 years; 88.9% female) were randomly sampled. Participants had attended an EBP workshop …


Midweek Memo, Georgia Southern University Dec 2025

Midweek Memo, Georgia Southern University

Midweek Memo

  • Applaud
  • Remember
  • Share
  • Experience
  • Around the Nest


Ai Context Automaton – Extended Architecture For Compliance-Aware Local Memory And Environmental Optimisation, David R P Chiesa Dec 2025

Ai Context Automaton – Extended Architecture For Compliance-Aware Local Memory And Environmental Optimisation, David R P Chiesa

Defensive Publications Series

AI Context Automaton introduces a dual-AI architecture that transforms stateless AI interactions into a stateful, compliance-aware, and environmentally optimised workflow. The system combines a local AI for memory management and compliance enforcement with a cloud-based AI for reasoning, leveraging a markdown-based knowledge base for persistent storage. By offloading memory operations and compliance checks to local devices, the architecture minimises repeated cloud compute cycles, reducing energy consumption, carbon footprint, and operational costs while ensuring adherence to organisational governance standards.


Spatial Conversations: Opportunities To Share Geographic Knowledge, L. Jesse Rouse, Barbara L. Maclennan, Susan J. Bergeron, H. Franklin Lafone Dec 2025

Spatial Conversations: Opportunities To Share Geographic Knowledge, L. Jesse Rouse, Barbara L. Maclennan, Susan J. Bergeron, H. Franklin Lafone

Anthropology and Geography

For more than twenty years geographers have taken advantage of “new media” to share information, make connections, and expand the “spatial conversation.” As blogs opened the door for informal self-publishing and communicating about narrow, focused topic areas, geographers began to use emerging media platforms to present ideas to a broader audience, more quickly and interactively, as new data and technologies became available. Audio podcasts and videos broadened the platforms for dissemination and provide a greater level of immersion through digital media. Between the open publishing and subscription opportunities, and interaction provided through comments and social media engagement, a dialectic was …


Pooled Randomised Quartet Trials Assessing Effectiveness Of A Single Pill For Hypertension, Simone Marschner, Mark D Huffman, Desi Quintans, Jody Ciolino, Abigail Baldridge, Danielle Lazar, Emily R Atkins, Graham S Hillis, Mark R Nelson, Markus Schlaich, Anthony Rodgers, Clara K Chow Dec 2025

Pooled Randomised Quartet Trials Assessing Effectiveness Of A Single Pill For Hypertension, Simone Marschner, Mark D Huffman, Desi Quintans, Jody Ciolino, Abigail Baldridge, Danielle Lazar, Emily R Atkins, Graham S Hillis, Mark R Nelson, Markus Schlaich, Anthony Rodgers, Clara K Chow

2020-Current year OA Pubs

BACKGROUND: Hypertension is a major cause of premature death worldwide, controlled by only one in five adults. Two trials (Australia and USA) found a single quadpill containing a quarter dosage of four classes of medication effective in reducing blood pressure (BP) among participants with hypertension. By pooling these trials, we can estimate the overall benefit of the quadpill and its heterogeneity across subgroups and two important barriers for BP control: clinician medication inertia and participant medication adherence.

METHODS: In a prespecified pooled individual participant data analysis of two QUARTET randomised, multicentre, double-blinded trials in people with hypertension using ≤1medication, quadpill …


Trametinib Decreased Intracerebral Hemorrhages And Endothelial-To-Mesenchymal Transition In Kras, Ohnmar Myint, Bridger Freeman, Jae Yeong Jeong, Hyejin Park, Samantha M Wilfur, Shuning Huang, Jung-Eun Park, Jakob Körbelin, Jaroslaw Aronowski, Eun S Park, Peng R Chen, Eunhee Kim Dec 2025

Trametinib Decreased Intracerebral Hemorrhages And Endothelial-To-Mesenchymal Transition In Kras, Ohnmar Myint, Bridger Freeman, Jae Yeong Jeong, Hyejin Park, Samantha M Wilfur, Shuning Huang, Jung-Eun Park, Jakob Körbelin, Jaroslaw Aronowski, Eun S Park, Peng R Chen, Eunhee Kim

Faculty, Staff and Student Publications

Background: Brain arteriovenous malformations (bAVMs) are a major risk factor for intracerebral hemorrhages in young patients. Recent clinical studies have reported that the majority of human bAVMs harbor somatic KRAS mutations. In our previous study, we confirmed the causal role of endothelial KRASG12V mutation in bAVM development in mice through hyperactivation of the MEK/ERK (extracellular signal-regulated kinase) pathway. However, the treatment efficacy of targeting MEK/ERK signaling in bAVMs, regarding clinical and biological outcomes, remains unclear.

Methods: In this study, we used the Food and Drug Administration-approved MEK inhibitor, trametinib, to treat mice with bAVMs induced by brain endothelial cell (EC)-specific …


Acceptance And Commitment Therapy: A Treatment Option For Substance Use Disorders, Miriam N. Mukasa, Ashley Yaugher, Ty Aller Dec 2025

Acceptance And Commitment Therapy: A Treatment Option For Substance Use Disorders, Miriam N. Mukasa, Ashley Yaugher, Ty Aller

All Current Publications

There are many evidence-based treatments for individuals experiencing substance use disorders (SUDs) that support both individuals and families. Psychological treatments are effective for a wide range of SUDs, making them a key approach for helping people with differing needs. This fact sheet provides information on treatments and provides more detail about acceptance and commitment therapy as a SUD treatment support.


Child Maltreatment And Recidivism: Do Maltreatment Patterns Influence General And Violent Reoffending?, Nan Li, Matt Shelton, Elena L. Grigorenko Dec 2025

Child Maltreatment And Recidivism: Do Maltreatment Patterns Influence General And Violent Reoffending?, Nan Li, Matt Shelton, Elena L. Grigorenko

Psychological Science Faculty Publications

This study examined whether patterns of maltreatment predicted reoffending among 5,194 justice-involved youth (JIY) from a large Texas juvenile probation department. Using latent class analysis on five maltreatment types (physical abuse, emotional abuse, sexual abuse, neglect, and exposure to domestic violence), we empirically identified three classes: “Poly-victimization” (17.8%; high across all types), “Psychological Maltreatment” (15.3%; high emotional abuse and neglect), and “Low Maltreatment” (66.9%; low/moderate across types). JIY in the “Poly-victimization” and “Psychological Maltreatment” classes were more likely to engage in general and violent reoffending within 1 year controlling for covariates. These findings highlight the varying importance of different maltreatment …


The Singlet Scalar State In A Chiral Ensemble In $Su(2)$ With Two Fundamental Flavours, Laurence Bowes, Vincent Drach, Patrick Fritzsch, Sofie Martins, Antonio Rago, Fernando Romero-Lopez Dec 2025

The Singlet Scalar State In A Chiral Ensemble In $Su(2)$ With Two Fundamental Flavours, Laurence Bowes, Vincent Drach, Patrick Fritzsch, Sofie Martins, Antonio Rago, Fernando Romero-Lopez

School of Engineering, Computing and Mathematics

Composite Higgs models are a class of Beyond the Standard Model (BSM) models proposed to address the hierarchy and naturalness problems associated with the Standard Model (SM) Higgs. A new QCD-like strongly interacting sector based on SU(2) with two fundamental flavours can be used to build a composite Higgs model which is not yet ruled out by experiment. The role of the singlet scalar resonance will affect Higgs phenomenology at the LHC. In this project our goal is to understand the properties of the singlet scalar state in the new strongly interacting sector in isolation as a first step to …


Bystander Interventions And Their Impact On Road Injury Outcomes: A Scoping Review, Nicholas Aveyard, George Stephen Russam, Jake Gluyas-Harris, Tim Nutbeam Dec 2025

Bystander Interventions And Their Impact On Road Injury Outcomes: A Scoping Review, Nicholas Aveyard, George Stephen Russam, Jake Gluyas-Harris, Tim Nutbeam

Peninsula Medical School

Background: Road injury remains a leading global cause of death and disability, particularly in low- and middle-income countries (LMICs) where emergency medical services (EMS) are often limited or incur prolonged response times. In many trauma cases, bystanders are the first to respond and may play a critical role in patient outcomes. While the importance of bystander cardiopulmonary resuscitation (CPR) in cardiac arrest is well-established, the evidence regarding bystander interventions in trauma care, particularly following road injury, is less well defined. This scoping review systematically examined the prevalence, nature, and impact of bystander interventions following trauma, with particular emphasis on road …


Cmsi Translations #25: A New Pillar For Distant Oceans: Concepts For The Chinese Navy's New Generation Of General-Purpose Destroyers, Ying Tian Dec 2025

Cmsi Translations #25: A New Pillar For Distant Oceans: Concepts For The Chinese Navy's New Generation Of General-Purpose Destroyers, Ying Tian

CMSI Translations

A recent unconfirmed rumor about the Chinese Navy developing a new general-purpose guidedmissile destroyer has stirred debate online. Many commenters argue that the Type 055 already offers exceptional capability across air defense, missile defense, anti-ship, anti-submarine, and general warfare roles, and is more than capable of meeting current mission needs. But because it’s expensive to build, it is not practical to produce in large numbers or to use for routine tasks, so it will likely remain a smaller part of the fleet. In contrast, the more affordable Type 052D class is limited by its size and displacement, which restricts how …


Matter Of Mantilla V. New York City Dept. Of Hous. Preserv. & Dev. Dec 2025

Matter Of Mantilla V. New York City Dept. Of Hous. Preserv. & Dev.

All Decisions

In this CPLR article 78 proceeding, the Court of Appeals affirmed the denial of a tenant's succession rights to a deceased brother's Mitchell-Lama apartment. The landlord (HPD) found the tenant failed to prove primary residency for the required one-year period prior to the brother's death, despite being an eligible family member and listed on income affidavits. While the tenant presented some evidence like SNAP correspondence and power of attorney over the brother's bank account, the Court held the agency had a rational basis for concluding this was insufficient. The Court emphasized its deferential standard of review for administrative determinations, upholding …


Estoppel Without Regard To Equity? The Puzzling Omission Of Promissory Estoppel’S Inequity Condition In Canada, Marcus Moore Dec 2025

Estoppel Without Regard To Equity? The Puzzling Omission Of Promissory Estoppel’S Inequity Condition In Canada, Marcus Moore

All Faculty Publications

Promissory estoppel plays an important role in enabling the enforcement of promises not made for consideration in cases where the promise was intended to and did induce a party to change its position in regard to preexisting legal rights. However, Canadian law on estoppel has been plagued by confusion and misunderstanding. This article addresses the internationally notable absence of an inequity requirement from promissory estoppel in Canada. The requirement’s absence is peculiar, in that estoppel’s very foundation is in equity, and it must assure that its effect is indeed equitable. Drawing on the Supreme Court of Canada’s decision in Trial …


Lithium–Sulfur Batteries: 3d Printed Tools And Assembly Techniques For Repeatable Lab-Scale Coin Cell Manufacturing, Daryl Miranda, Tosif Aliyev, Lamija Kovacevic, Sivapriya Voleti, Jaydie Lee, Kathleen Meehan, Monica C. So, Philip T. Dirlam Dec 2025

Lithium–Sulfur Batteries: 3d Printed Tools And Assembly Techniques For Repeatable Lab-Scale Coin Cell Manufacturing, Daryl Miranda, Tosif Aliyev, Lamija Kovacevic, Sivapriya Voleti, Jaydie Lee, Kathleen Meehan, Monica C. So, Philip T. Dirlam

Faculty Research, Scholarly, and Creative Activity

The coin cell form factor has become a standard in energy storage research owing to its relatively low cost, low quantity of requisite electroactive material, fast experimental turnover, and capability to generate publishable quality data. Coin cell assembly at the lab-scale requires precise manual alignment of the many internal components of a cell to yield a properly functioning device. Truly repeatable device assembly presents a significant challenge to the acquisition of reliable data. In this report, we present a three-dimensional (3D) printable design for a coin cell alignment device and describe techniques for a generalized workflow to achieve reproducible coin …


Mineralocorticoid Receptor Antagonists For Acute Myocardial Infarction: A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Song Peng Ang, Jia Ee Chia, Bruno Bezerra Lima, Jose Iglesias, Eunseuk Lee, Chayakrit Krittanawong, Mahboob Alam, Debabrata Mukherjee Dec 2025

Mineralocorticoid Receptor Antagonists For Acute Myocardial Infarction: A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Song Peng Ang, Jia Ee Chia, Bruno Bezerra Lima, Jose Iglesias, Eunseuk Lee, Chayakrit Krittanawong, Mahboob Alam, Debabrata Mukherjee

Faculty, Staff and Students Publications

Background: The role of mineralocorticoid receptor antagonists (MRAs) in acute myocardial infarction (MI) remains controversial, with conflicting evidence from landmark trials. We aimed to assess the impact of MRAs on mortality and cardiovascular outcomes post-acute MI.

Methods: We systematically searched PubMed, Embase and Cochrane CENTRAL databases up to February 2025 for randomised controlled trials comparing MRAs with placebo or standard care in adults experiencing acute MI. Primary outcome was all-cause mortality; secondary outcomes included cardiovascular mortality, heart failure, recurrent MI and ventricular arrhythmia. Data were pooled using random-effects models, with heterogeneity explored via subgroup analyses and meta-regression.

Results: 15 trials …


Presence Of Eosinophils May Represent An Earlier Stage In Achalasia Pathogenesis, Andrea Costantini, Chandra Prakash Gyawali, Francesca Forattini, Valentina Angerilli, Matteo Ghisa, Luca Provenzano, Giovanni Capovilla, Loredana Nicoletti, Michele Valmasoni, Matteo Fassan, Edoardo Vincenzo Savarino, Renato Salvador Dec 2025

Presence Of Eosinophils May Represent An Earlier Stage In Achalasia Pathogenesis, Andrea Costantini, Chandra Prakash Gyawali, Francesca Forattini, Valentina Angerilli, Matteo Ghisa, Luca Provenzano, Giovanni Capovilla, Loredana Nicoletti, Michele Valmasoni, Matteo Fassan, Edoardo Vincenzo Savarino, Renato Salvador

2020-Current year OA Pubs

BACKGROUND: Intraepithelial eosinophils have been described in patients with esophageal motor disorders. Conversely, motor disorders and even achalasia have been reported in patients with eosinophilic esophagitis (EoE).

OBJECTIVES: This prospective study aimed to further investigate the association between eosinophilia and achalasia.

DESIGN: This is a prospective study.

METHODS: A series of 30 consecutive treatment-naïve achalasia patients (mean age: 45.5 years, 53% female) undergoing laparoscopic myotomy were prospectively enrolled. Preoperative demographic and clinical data, radiological findings, and high-resolution manometry (HRM) features were collected. Patients underwent upper endoscopy with biopsy sampling before surgery, and two samples of distal esophageal muscle were obtained …


Limited Agreement On Acl Tear Location Between Arthroscopy And Mri: A Prospective Evaluation, Richard Silverman, Derrick M Knapik, Matthew V Smith, Jonathan C Baker, Kelby Napier, Matthew J Matava, Robert H Brophy Dec 2025

Limited Agreement On Acl Tear Location Between Arthroscopy And Mri: A Prospective Evaluation, Richard Silverman, Derrick M Knapik, Matthew V Smith, Jonathan C Baker, Kelby Napier, Matthew J Matava, Robert H Brophy

2020-Current year OA Pubs

BACKGROUND: Renewed interest in anterior cruciate ligament (ACL) preservation has led to increased focus on tear location within the knee joint in treatment decisions, with primary ACL repair reserved for proximal tears. Retrospective studies have reported varying tear locations in adults when assessed on magnetic resonance imaging (MRI), with few studies comparing tear location on MRI versus intraoperative findings.

PURPOSE: To prospectively determine the distribution of ACL tear location assessed on MRI versus intraoperative evaluation to test the hypothesis that < 15% of ACL tears are proximal type avulsions.

STUDY DESIGN: Cohort study (Diagnosis); Level of evidence, 2.

METHODS: A total of 174 patients with clinically confirmed full-thickness ACL …


Genomic Characterization Of Colorectal Tumors: Insights Into Significantly Mutated Genes, Pathways, And Survival Outcomes, Tabitha A Harrison, Yin Cao, Et Al. Dec 2025

Genomic Characterization Of Colorectal Tumors: Insights Into Significantly Mutated Genes, Pathways, And Survival Outcomes, Tabitha A Harrison, Yin Cao, Et Al.

2020-Current year OA Pubs

BACKGROUND: Identifying significantly mutated genes in tumors aids in understanding disease etiology and survival and may aid in the discovery of new drug targets. We aimed to detect and characterize mutated genes from a large, well-characterized group of colorectal cancers.

METHODS: In tumor and paired normal samples from 6,111 colorectal patients, we sequenced 199 genes identified from whole exome sequencing of over 1,100 tumors. Analyses focused on non-silent mutations. We classified significantly mutated genes after stratification by hypermutation status, and estimated associations of mutated genes/pathways with disease-specific (DS)-survival using Cox regression, adjusting for age, sex, mutation burden, hypermutation status, and …


Applied Methods For Matching Implementation Strategies To Determinants: A Scoping Review Of Scientific And Grey Literature, And Qualitative Exploration Of Practice Experiences, Christiaan Vis, Leti Van Bodegom-Vos, Bethany Hipple-Walters, Byron J Powell, Erwin Ista, Femke Van Nassau Dec 2025

Applied Methods For Matching Implementation Strategies To Determinants: A Scoping Review Of Scientific And Grey Literature, And Qualitative Exploration Of Practice Experiences, Christiaan Vis, Leti Van Bodegom-Vos, Bethany Hipple-Walters, Byron J Powell, Erwin Ista, Femke Van Nassau

2020-Current year OA Pubs

BACKGROUND: Tailored implementation addresses the inherent dynamic complexity and heterogeneous nature of implementation practice. In general, tailored implementation involves setting implementation objectives, identifying determinants, matching strategies to those determinants, and developing an evaluation plan. How matching a specific implementation strategy to a determinant is done remains largely unknown. This study aimed to provide an overview of methods for matching strategies that have been applied in research and practice.

METHODS: A scoping review of scientific and grey literature was conducted. A Rapid Assessment Procedure approach guided the design and analysis. Five online scientific bibliographic databases and various Dutch websites were searched …