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An Integrated Multivariate Econometric Modeling Framework For Risky Driving Behavior Related Crashes: Evaluating Crash Risk And Severity Across Zones, Pabitra Kumar Roy

Dissertations and Theses

Rapid advancements in crash modeling have yet to fully integrate multiple behavior-driven crash types and their severity outcomes within a single, scalable framework, specially in a way that captures the sequential nature of these behaviors where one risky action may amplify another. This study proposed an integrated multivariate econometric framework to jointly model crash frequency and severity outcomes for three major behaviorally driven crash types: alcohol-related, distraction-related, and aggressive-driving-related crashes. Specifically, using Oregon's 2022 census block group-level crash data, we propose an Integrated Multivariate Negative Binomial – Generalized Ordered Probit Fractional Split (IMNB–GOPFS) model to analyze these dimensions simultaneously while …

P-15 Peptide Enhanced Bone Graft Improves Time To Fusion In Transforaminal Lumbar Interbody Fusion: A Randomized, Controlled, Investigational Device Exemption Study, James S. Harrop, Michael P. Steinmetz, John E. O'Toole, Christopher D Chaput, Rick C. Sasso, K. Brandon Strenge, Greg Maislin, Jeffrey P. Mullin, Thomas B. Freeman, Anthony Guanciale, Howard Lantner, Michael E. Janssen, David G. Schwartz, John M. Small, Wellington K. Hsu, Paul M. Arnold

Department of Neurosurgery Faculty Papers

STUDY DESIGN: Prospective, multicenter, single-blind, randomized, and controlled pivotal study.

OBJECTIVE: Compare time-to-fusion in patients treated with P-15L (PearlMatrix TM P-15 peptide enhanced bone graft) versus local autograft over 24 months and evaluate changes in pain and quality of life at 24 months relative to baseline.

SUMMARY OF BACKGROUND DATA: P-15L, an FDA-designated breakthrough device, is a composite bone graft with P-15, a 15-amino acid polypeptide that promotes cellular adhesion, proliferation, and differentiation to support bone formation.

METHODS: Patients (22-80 y) with degenerative disc disease were randomized to the investigational (P-15L) or control (local autograft) group during single-level transforaminal lumbar …

A Fish & A Bird, Deanna Moorehead

Theses

As a curtain of trees opens and dawn breaks over the glistening waters of Lake Ontario, a fish and a bird spot each other through the surface and fall madly in love. They dance and sing together from their respective atmospheres, yet each time the bird soars past the water's edge and onto the beach, the fish cannot follow. Night after night, by the light of the moon, the fish trains herself to leap out of the water, hoping to breach high enough to join her beau above. Late one afternoon, the fish approaches the shore, where the bird stands …

Physiological Demands Of Virtual Reality Exercise Games: An Analysis Of Energy Expenditure And Exercise Intensity, Neil Panchal

Doctorate in Kinesiology

Virtual reality (VR) technology offers potential as an exercise modality, yet comprehensive physiological assessments using gold-standard methodology remain limited. This study investigated the physiological demands of three VR fitness games, Beat Saber, Punch Fit, and RUN, by examining exercise intensity, energy expenditure, and time spent above American College of Sports Medicine (ACSM) intensity thresholds. Thirty-two college students (ages 18-32, M = 23.9 ± 3.1 years) completed maximal exercise testing to establish VO₂max, followed by a VR gaming session. Physiological responses were measured using portable indirect calorimetry and heart rate monitoring. Repeated-measures ANOVAs revealed significant differences between games, with large effect …

The Johnson-Křížek-Mercier Elasticity Element In Higher Dimensions, Jay Gopalakrishnan, Johnny Guzman, Jeonghun J. Lee

Mathematics and Statistics Faculty Publications and Presentations

Mixed methods for linear elasticity with strongly symmetric stresses of lowest order are studied in this paper. On each simplex, the stress space has piecewise linear components with respect to its Alfeld split (which connects the vertices to barycenter), generalizing the Johnson–Mercier two-dimensional element to higher dimensions. Further reductions in the stress space in the three-dimensional case (to 24 degrees of freedom per tetrahedron) are possible when the displacement space is reduced to local rigid displacements. Proofs of optimal error estimates of numerical solutions and improved error estimates via postprocessing and the duality argument are presented.

Metabolomic Profiling Reveals Brain Lipid Alterations In Pex7-Deficient Models Of Rhizomelic Chondrodysplasia Punctata, Riya Sankhe, Meredith I Williams, Wedad Fallatah, Laura Mackay, Mary Layne Brown, Pranjali Bhagwat, Sarah H Elsea, Nancy Braverman, Michael F Wangler

Duncan NRI Faculty and Staff Publications

Rhizomelic chondrodysplasia punctata type 1 (RCDP1) is a peroxisomal disorder characterized by skeletal shortening, intellectual disability, seizures, cataracts, and reduced lifespans. RCDP1 is caused by biallelic loss-of-function variants in PEX7, which encodes a protein required for importing select enzymes into the peroxisome matrix, including those essential for ether lipid synthesis (e.g., plasmalogens) and the branched-chain fatty acid catabolism. Plasmalogen deficiency is a hallmark of RCDP1 and other peroxisomal disorders, including RCDP types 2-5 (RCDP2-5) and Zellweger spectrum disorders (ZSD). Here, we performed comprehensive metabolomic profiling of clinical samples from RCDP patients and Pex7-deficient mouse models. We identified profound …

Adaptive Neuromodulation Dialogues: Navigating Current Challenges And Emerging Innovations In Neuromodulation System Development, Frederik Lampert, Matthew R Baker, Michael A Jensen, Amir H Ayyoubi, Christian Bentler, Jessica L Bowersock, Rosana Esteller, Jeffrey A Herron, Graham W Johnson, Daryl R Kipke, Christopher K Kovach, Vaclav Kremen, Filip Mivalt, Joseph S Neimat, Theoden I Netoff, Enrico Opri, Alexander Rockhill, Joshua M Rosenow, Kristin K Sellers, Nathan P Staff, Chandra Prakash Swamy, Ashwin Viswanathan, Gerwin Schalk, Timothy Denison, Dora Hermes, Nuri F Ince, Peter Brunner, Gregory A Worrell, Kai J Miller

Faculty, Staff and Students Publications

Adaptive neuromodulation systems and implantable brain-computer interfaces have made notable strides in recent years, translating experimental prototypes into clinical applications and garnering substantial attention from the public. This surge in interest is accompanied by increased scrutiny related to the safety, efficacy, and ethical implications of these systems, all of which must be directly addressed as we introduce new neurotechnologies. In response, we have synthesized the insights resulting from discussions between groups of experts in the field and summarized them into five key domains essential to therapeutic device development: (1) analyzing current landscape of neuromodulation devices and translational platforms (2) identifying …

Single-Nucleus Multiomics Reveals The Disrupted Regulatory Programs In Three Brain Regions Of Sporadic Early-Onset Alzheimer’S Disease, Andi Liu, Citu Citu, Nitesh Enduru, Xian Chen, Chia-Hao Tung, Tirthankar Sinha, Sofia E Sepulveda, Astrid M Manuel, Damian Gorski, Brisa S Fernandes, Meifang Yu, Paul E Schulz, Lukas M Simon, Claudio Soto, Zhongming Zhao

Faculty, Staff and Student Publications

Sporadic early-onset Alzheimer’s disease (sEOAD) represents a substantial but less-studied subtype of Alzheimer’s disease (AD). Here, we generated a single-nucleus multiome atlas derived from the postmortem prefrontal cortex, entorhinal cortex, and hippocampus of nine individuals with or without sEOAD. Comprehensive analyses were conducted to delineate cell type–specific transcriptomic changes and linked candidate cis-regulatory elements (cCREs) across brain regions. We prioritized eight conservative transcription factors in glial cells in multiple brain regions, including RFX4 in astrocytes and IKZF1 in microglia, which are implicated in regulating sEOAD-associated genes. Moreover, we identified the top 25 altered intercellular signaling between glial cells …

Consciousness Studies In Community: Allan Leslie Combs’S Enduring Vision, Debby Flickinger Phd, Rebecca A. Damien Phd

Journal of Conscious Evolution

Consciousness studies can be found in many different disciplines. Allan Leslie Combs held an inclusive view of consciousness that was not limited to any one branch, and he inspired us to explore consciousness through many doorways. Together the authors share narratives about teaching and learning with Combs while reviewing key areas shaped by his legacy, including gatherings, archetypes, psychology, and synchronicity. Our shared intention is to honor Leslie’s legacy through a narrative that comes from the heart as well as the mind.

Keywords: consciousness studies, gatherings, archetypes, synchronicity, Allan Leslie Combs

Comparison Of Cervical Spine Injury Clinical Prediction Rules For Children After Blunt Trauma, Lois K. Lee, Fahd A. Ahmad, Lorin R. Brown, Monica Harding, Lawrence Cook, Kathleen Adelgais, Rebecca K. Burger, Alexander Rogers, Leah Tzimenatos, Lauren C. Riney, Daniel Rubalcava, Caleb E. Ward, Kenneth Yen, Julie C. Leonard

2020-Current year OA Pubs

No abstract provided.

Baseline Exposure-Response Assessment Of Metals From Dried Blood Spots And Personal Household Air Pollution Concentrations Among Pregnant Women In Rwanda: Household Air Pollution Intervention Network Trial, Adolphe Ndikubwimana, Lisa De Las Fuentes, Victor G Dávila-Román, Et Al.

2020-Current year OA Pubs

BACKGROUND: Exposure to metals from the combustion of biomass via inhalation may result in negative health outcomes affecting a variety of organs and systems. Pregnant women cooking with biomass fuels may be exposed to metals, such as lead (Pb) and cadmium (Cd), and have unique risks for adverse health effects with potential impacts on the growing fetus. We assessed the associations between household air pollution and metals detected in dried blood spots from pregnant women at baseline in Rwanda.

METHODS: We analyzed data from 781 pregnant women aged 18-35 years who resided in rural households using biomass fuel and who …

Graphical Display Of A Career In Chronological Order With Achievement Percentiles, Safwan Samla

Defensive Publications Series

A digital representation of a person’s career is provided in a manner that is easy to follow and provides important statistics relating to achievement assessments relative to others. A person’s career can be displayed through a graphical user interface comprising an X and Y plot wherein the X-axis comprises a timeline determined by a person’s career and the Y-axis comprises data-based categories pertaining to different achievement and experiences from the person’s career.

The Contributors, Contributors Contributors

Budhi: A Journal of Ideas and Culture

Contributors

Notes For Contributors, Contributors Contributors

Budhi: A Journal of Ideas and Culture

Contributors

Socrates And Early Buddhist Medical Ethics: Foundations Of Moral Reasoning In The Care Of Body And Mind, Chandima Gangodawila

Budhi: A Journal of Ideas and Culture

While Buddhist traditions articulate a parallel moral vision in the early discourses of the Pāli Canon, Western traditions usually locate the roots of ethical reasoning in Socratic inquiry. Especially in their approaches to bodily care, spiritual well - being, and moral responsibility, this article contends that both Socratic and Early Buddhist ideas converge on fundamental principles in medical ethics. Through a comparative textual and philosophical study, the paper examines how Socratic dialectics and the Buddha's diagnostic approach to dissatisfa ction/ suffering (dukkha) both produce frameworks for ethical healthcare anchored in the development of virtue, wisdom, and care for the integrity …

Inclusive Stem Education In Nigerian Schools:An Emerging Pathway For Substainable Development, Oginni Aderonke Margaret Dr., Awobodu Victoria Yetunde Dr., Olusegun Bisola Esther Miss

Journal of Educational Research and Practice

Inclusive STEM (science, technology, engineering, and mathematics) education plays a vital role in promoting equitable learning opportunities and fostering sustainable development. However, in Nigeria, many marginalized student groups face barriers that hinder their full participation in STEM fields. This study examines the factors impeding inclusivity in STEM education and their effects on students’ motivation, academic performance, and awareness of sustainable development in Lagos State. Employing a survey research design, data were gathered from 550 students selected through simple random sampling across 21 secondary schools in Education Districts I, III, and V. A researcher-developed questionnaire was used for data collection. To …

Lessons Learned: Andreas Verykios And Kostas Tsatsaronis, Mercedes Cardona

Journal of Financial Crises

Andreas Verykios was appointed in 2018 to lead the board of directors of the General Council of the Hellenic Financial Stability Fund (HFSF), an independent special purpose vehicle created to stabilize the Greek banking sector in the wake of the country’s debt crisis. The Greek economy was badly affected by the Global Financial Crisis (GFC) and the Sovereign Debt Crisis, when the government was found to have underreported its fiscal deficits and public debt. This led to a downgrade and eventual default of its sovereign bonds, requiring assistance from the European Commission. From 2010 through 2018, the commission implemented three …

Lessons Learned: Paul Tucker, Salil Gupta

Journal of Financial Crises

After joining the Bank of England (BoE) in 1980, Sir Paul Tucker held a number of positions of increasing responsibility including serving as a member of several key committees. Tucker played a crucial role in the BoE’s response to the Global Financial Crisis (GFC) as director for markets, through March 2009, then as deputy governor of the bank until November 2013. Post-crisis, he has been instrumental in constructing the international regulatory framework on financial stability. From 2016 to 2021, Tucker also chaired the Systemic Risk Council.

Currently, Tucker is a research fellow at Harvard Kennedy School, Mossavar-Rahmani Center for Business …

Lessons Learned: Ewald Nowotny, Maryanne Chute Lynch, Rosalind Z. Wiggins

Journal of Financial Crises

Ewald Nowotny was appointed governor of the National Bank of Austria in September 2008 at the start of the Global Financial Crisis (GFC), having previously served as a vice president of the European Investment Bank in Luxembourg, the house bank of the European Union. Nowotny participated in the implementation of the multilateral stabilization framework known as the Vienna Initiative, which helped restore stability in the financial markets of Central, Eastern, and Southeastern Europe during the GFC. Working with the Austrian Central Bank, the European Commission, and the International Monetary Fund (IMF), he steered the Austrian economy away from recession. During …

Lessons Learned: Pedro Machado, Mercedes Cardona

Journal of Financial Crises

Pedro Machado began his career as a legal adviser to the European Central Bank in the years leading up the Global Financial Crisis (GFC), then joined the Bank of Portugal (BOP) in 2006, where he has held several positions. He was chief of staff to Portugal’s minister of state and finance in 2011, during the European Sovereign Debt Crisis, when the government negotiated a bailout with the International Monetary Fund (IMF) and European Union. He returned to the BOP, as deputy director of the prudential supervision department, while the program was being implemented. The EUR 78 billion bailout was largely …

Central Bank Crisis Interventions: A Review Of The Recent Literature On Potential Costs, Patrick Aldridge, David A. Cimon, Rishi Vala

Journal of Financial Crises

Central banks may engage in large-scale lending and asset purchases to stabilize financial markets and implement monetary policy during crises. The ability of these actions to restore financial market functioning is well documented; however, they come with costs. We provide a literature review of the costs associated with these post-Global Financial Crisis central bank actions, without commenting on the net benefits they provide. We find support for the premise that crisis actions may negatively impact market liquidity, distort asset prices, increase rent-seeking and inefficient uses of the liquidity provided by the central bank, create international spillovers, and create distortions in …

Proposing Augmented Reality Game-Based Learning For Higher Education, Anna C. Zaldivar

The Scholarship Without Borders Journal

Simulating the role of an instructional technologist, negotiation takes place to implement the AR technology for use in a higher education institution. There are arguments both for and against the use of augmented reality for higher education. Overall, examining and highlighting these arguments to make an important decision that will shape learners' future. Using BATNA and examining arguments during the negotiation process.

Understanding Generation Z Polarization: Findings From A Preliminary Replication Study, Liane Weintraub

The Scholarship Without Borders Journal

Amid rising polarization and declining trust in democratic institutions, Generation Z (Gen Z) faces unique challenges in navigating civic discourse. This study presents comparative findings from two survey cohorts (2023, n = 56; 2025, n = 25) examining Gen Z students’ political identity, discourse habits, interpersonal trust, and civic attitudes. Framed by Social Identity Theory (SIT), Cultural Intelligence (CQ), and discourse theory, the study explores how ideological difference and identity signaling shape students’ willingness to engage across divides. Findings indicate continuity in partisan skepticism and discourse openness, but also growing fatigue, reduced trust, and ambivalence toward equity. While affective polarization …

Black Women And Latinas In Stem: A Systematic Review Of Literature, Karin Moore

The Scholarship Without Borders Journal

This systematic review of literature examines scholarly studies conducted on Black women and Latinas in STEM fields and in STEM higher education. Women are underrepresented in STEM, and on average they comprise 27% of the STEM population (National Science Foundation, 2017). Black women and Latinas are even further underrepresented in STEM by making up only 14.58 % and 3% of the employees in STEM industries (Hispanic Heritage Foundation, 2020; National Science Foundation, 2021). Barriers for all women are the focus of much of the body of literature in STEM (Beach et al., 2024; Moore, 2024). Isolating specific challenges Black women …

Extending The Emotional And Multiple Intelligence Theories: Integrating Cultural And Spiritual Intelligence Constructs To Fill Research Gaps, Kimberly J. Mcdonald

The Scholarship Without Borders Journal

This proposed mixed-methods convergent research study aims to explore extending the Emotional Intelligence (EI) and Multiple Intelligences Theories by integrating Spiritual Intelligence (SI) and Cultural Intelligence (CQ) constructs. The goal is to explore the interconnectedness of these intelligences to bridge existing research gaps concerning leadership, EI, SI, and CQ. By employing both quantitative and qualitative data collection methods from organizational leaders, this study seeks to develop a more comprehensive and holistic understanding of leadership efficacy across various organizational contexts. The anticipated outcomes aim to contribute to the body of knowledge and potentially impact leadership development in business, education, and other …

Article Title: Deconstructing Power And Gender: A Foucauldian Discourse Analysis Of Biopolitics, Necropolitics, And Sexual Scripts In Feminicide In Puerto Rico., Migdalia Marrero-Lafontaine

The Scholarship Without Borders Journal

Feminicide and gender violence cases in the last several decades in Puerto Rico have continuously increased, suggesting that this problem becomes worse as time passes. This study, therefore, focuses on identifying actionable insights that paint a picture of the impact it has on women over the age of 18 in Puerto Rico. In order to achieve this objective, the study relies on a strong theoretical framework that is made up of Foucauldian discourse analysis, necropolitics, and sexual scripts theories. One of the core findings of this research is that Puerto Rico’s colonial history and cultural norms sustain a cycle of …

The Detrimental Impact Of Early Childhood Exposure To Pornography, Leica Marie Estomo

The Scholarship Without Borders Journal

As pornography continues to become more easily and readily accessible, children are at higher risk of viewing it. This work aims to investigate the destructive impact of premature exposure to pornography, and the negative perceptions of sex and decision-making towards it as a result. The operational definition used defines “early exposure” as prepubescents (children of elementary-grade school ages) viewing explicit material through involuntary and accidental initial engagement, and “decision-making” as moral agency and choice of response and action. The populations searched focused more on American culture and its lens on sex and pornography, with the incorporation of other cultural frameworks …

Equity And Effectiveness In Advanced Mathematics Education: A Literature Review Of Ap Calculus, Cambridge Aice, And Ib Curricula, Jinhee Lee

The Scholarship Without Borders Journal

This literature review investigates equity and effectiveness of three globally recognized advanced high school mathematics programs: AP Calculus, Cambridge International Advanced International Certification of Education (AICE) Advanced Level (A-Level) Mathematics, and International Baccalaureate (IB) Mathematics High Level. Access to advanced mathematics is unequally distributed, impacting underprivileged students (Bressoud, 2021). This review examines curriculum content, teaching methods, and assessment strategies in alignment with college admissions, depth of conceptual understanding, inclusion of diverse approaches, and assessment accessibility. Findings will contribute to informed curriculum choices for students and inform equitable practices for educators.

Abc Pharmaceutical Company Change Model: Implementing J.P. Kotter's 8-Step And Adkar Change Models For Ethical Alignment, Shelbi B. Chandler, Amalfi Gayosso, Alison Lawton, Ali Holness-Roland

The Scholarship Without Borders Journal

In this paper, we use the pseudonym ABC Pharmaceuticals (ABC) to refer to the company under examination, GlaxoSmithKline (GSK). ABC Pharmaceutical (ABC) must assess, adapt, and change to ensure regulatory compliance, maintain and attract employees, and remain competitive. ABC has a history of erroneous practices and is at risk internally with employees, and externally with regulators and the public sectors. The authors applied J.P. Kotter’s (1996) 8-step and the ADKAR (Hiatt, 2006) models for change management. J.P. Kotter’s top-down model addresses leadership’s role in creating a compelling vision aligned with its actions, and the ADKAR bottom-up model assesses employees’ readiness …

Roger Lewis Zachery

African American Funeral Programs

Funeral program for Roger Zachery. Service was held in Atlanta, Georgia