Digital Commons Network^™

Rigorous Validation Of Machine Learning Models For Orthodontic Extraction Prediction Using Nested Cross-Validation And Smotenc-Integrated Pipelines., Anh Thi-Ngoc Do, Hung Trong Hoang, Thuy-Trang Thi Ho, Hieu Ngoc Le

Journal of Dental Sciences

Background/purpose: Machine learning (ML) in orthodontics often suffers from optimistic bias due to data leakage and improper handling of class imbalance. This study implemented and evaluated a production-grade validation framework - nested cross-validation (CV) - for three distinct algorithm classes (logistic regression, random forest, and gradient boosting) using a consensus-labeled orthodontic dataset.

Materials and methods: A retrospective dataset of 500 patients (334 non-extraction/166 extraction) was curated with 41 processed features. Two stratified split protocols (70/30 and 80/20) were evaluated to assess model robustness. To ensure methodological rigor, a 5-fold outer/3-fold inner nested cross-validation was implemented. Crucially, SMOTENC (synthetic minority over-sampling …

Deciphering Novel Targets In Salivary Gland Pleomorphic Adenoma By Integrating Plasma Proteomics And Parotid Transcriptomics Analyses, Yuchen Fan, Suning Mao

Journal of Dental Sciences

No abstract provided.

Oral Health-Related Quality Of Life And Diabetes Outcomes: Evidence From A Nationally Representative U.S. Sample, Hsueh-Fen Chen, Jou-Hsun Lee

Journal of Dental Sciences

No abstract provided.

Self-Perceived Attractiveness Of Labiomental Angles In Taiwanese And Caucasian Males: A Comparative Study Before And After Orthodontic Education Among Dental Students, Shih-Chieh Chen, Chun-Ming Chen

Journal of Dental Sciences

No abstract provided.

Artificial Intelligence-Powered Chatbots’ Responses To Orthodontic Questions From The Dentistry Specialization Examination: Accuracy And Source Evaluation, Berrak Çakmak, Tevhide Sökmen, Burcu Balos‚ Tuncer

Journal of Dental Sciences

No abstract provided.

Clinical Red Flags And Referral Strategies For Odontogenic Deep Neck Space Infections: The Primary Care Dentist’S Role As The First Line Of Defense, Sih-Yi Wu

Journal of Dental Sciences

No abstract provided.

The Clinical Applications Of Platelet-Rich Plasma And Platelet-Rich Fibrin Combined With Photobiomodulation In Regenerative Dentistry: A Literature Review, Maryam Pourhajibagher, Rashin Bahrami, Abbas Bahador

Journal of Dental Sciences

Regenerative dentistry seeks to restore oral tissues through biologically driven therapies that stimulate endogenous healing. Among these, autologous platelet concentrates—namely platelet-rich plasma (PRP) and platelet-rich fibrin (PRF)—serve as reservoirs of growth factors such as platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), vascular endothelial growth factor (VEGF), and insulin-like growth factor (IGF), which promote angiogenesis, cell proliferation, and extracellular matrix formation. Complementing these biological mediators, photobiomodulation (PBM) represents a non-invasive light-based therapy that enhances mitochondrial activity, modulates inflammation, and accelerates tissue regeneration. Accumulating evidence suggests that combining PRP or PRF with PBM produces synergistic effects that surpass those achieved by …

Deep Learning-Based Automated Per-Tooth Detection And Segmentation From Unretracted Smile Photographs, Hsuan Chen, Khoa Dang Nguyen, Hong Thi-Phuong Doan, Mu-Chen Yang, Ya-Chu Chang, Anand Marya, Guang Hong, Ding-Han Wang, Ming-Lun Hsu

Journal of Dental Sciences

Background/purpose: Natural smile photographs are universally accessible yet no automated method achieves clinically acceptable per-tooth detection from these images. Existing frameworks require lip-retracted intraoral views, and prior work on smile images achieved insufficient accuracy. This study developed a per-tooth detection and segmentation pipeline for natural smile photographs and assessed its applicability to digital smile design.

Materials and methods: A total of 1,471 smile photographs were annotated via model-assisted labeling. Fifteen You Only Look Once (YOLO) models across three architecture families and five size tiers were compared. A two-stage pipeline combined the best-performing detector with high-quality Segment Anything Model (HQ-SAM) for …

A Bibliometric Evolution Of Molecular Mechanisms And Emerging Research Trends Of Therapeutic Resistance In Oral Cancer, Chu-Yen Chien, Ying-Chen Chen, Jia-Rong Wu, Hsu-Hua Chu, Yi-Jen Hung, Yi-Shing Shieh

Journal of Dental Sciences

Background/purpose: Drug resistance has served as a primary determinant of treatment failure and disease recurrence in oral cancer. The present study aimed to evaluate the global research landscape of drug resistance mechanisms in oral cancer by integrating bibliometric mapping with bioinformatic validation.

Materials and methods: A comprehensive dataset of 1660 publications was retrieved from the Scopus database. Bibliometric analyses were performed using Biblioshiny and VOSviewer to evaluate publication trends, collaborative networks, and thematic evolution. To bridge research trends with biological mechanisms, 1469 genes associated with oral cancer and drug resistance were extracted from the GeneCards database and subjected to functional …

Universal Coverage But Unequal Access: An Area-Level Statistical And Policy Analysis Of Taiwan’S Dental Workforce, Chien-Yang Yeh, Shih-Hsien Yang, Wei-Chia Su, Hsin-Hu Chen, Wei-Chin Hsu, Su-Feng Chen

Journal of Dental Sciences

Background/purpose: Universal health insurance coverage does not necessarily ensure equitable access to dental care. This study examined Taiwan’s dental workforce distribution using area-level statistical analysis and interpreted the findings through an oral health equity perspective.

Materials and methods: Publicly available county/city-level data on practicing dentists in Taiwan were analyzed. Dentist density was calculated as dentists per 10,000 population. Geographic variation was assessed using descriptive statistics, z-scores, quartile classification, highest-to-lowest ratio, coefficient of variation, and population-weighted Gini coefficient. Group differences were compared by geographic classification using Welch’s t-test, Mann–Whitney U test, Hedges’ g, and Cliff’s delta. Findings were further …

Active Learning-Assisted Deep Learning For Automated Maxillary Sinus Segmentation In Dental Cone-Beam Computed Tomography, Hsuan Chen, Khoa Dang Nguyen, Chih-Ling Chang, Hong Thi-Phuong Doan, Ya-Chu Chang, Thantrira Porntaveetus, Guang Hong, Wen-Liang Lo, Ding-Han Wang, Ming-Lun Hsu

Journal of Dental Sciences

Background/purpose: Accurate automated segmentation of the maxillary sinus in cone-beam computed tomography (CBCT) scans is crucial for dental implant planning, sinus lift procedures, and pathological assessment, yet there remains a notable lack of publicly available models and datasets for this task. This study developed and evaluated a deep learning model for automated maxillary sinus segmentation using an active learning approach to minimize annotation effort while achieving high accuracy.

Materials and methods: We utilized 249 CBCT scans from the publicly available CTooth+ and STS-Tooth datasets. Ground truth annotations were generated through semi-automated segmentation in 3D Slicer with validation by five expert …

Do Anatomy, Physiology And Biochemistry Subject Scores Predict Future Academic Performance? A Longitudinal Analysis Of Undergraduate Dental Students Across All Professional Years., Shahid Akhtar Akhund, Hassan Shaibah

Journal of Dental Sciences

Background/purpose: Basic sciences subjects including anatomy, physiology and biochemistry form the foundation of the Bachelor of Dental Surgery (BDS) programme. However, empirical evidence linking the basic science academic performance to sustained academic achievement across subsequent clinical years remains limited. This is true for low and medium sized economies like Pakistan.

Materials and methods: A retrospective, quantitative, and longitudinal cohort study was conducted.  The deidentified data from a representative dental college was used. Basic science examination scores from the 1^st professional year examination served as predictor variables. The examination scores across 14 subjects served as outcome variables. Pearson product-moment correlations …

Deer Antler Tip Cell Culture Supernatant Restores Endothelial Barrier Function And Angiotensin Converting Enzyme 2/Endothelial Nitric Oxide Synthase Nitric Oxide Signaling Impaired By Porphyromonas Gingivalis Lipopolysaccharide, Ming-Shou Hsieh, Ya-Ting Yang, Chin-Sheng Huang, Ting-Yi Renn, Chuen-Kai Wang, Chia-Chen Hsu, Wei Jen Chang, Yu-Sheng Chang

Journal of Dental Sciences

Background/purpose:

Periodontal inflammation contributes to endothelial dysfunction, but effective biologically active strategies for vascular protection remain limited. This study investigated whether deer antler tip cell culture supernatant could rescue Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) induced endothelial injury and restore endothelial homeostasis.

Materials and methods:

Velvet antler tissues from the tip, shaft, and burr regions were examined histologically and used for primary cell isolation. Human umbilical vein endothelial cells were exposed to Pg-LPS or indirectly co-cultured with LPS-stimulated THP-1-derived macrophages. Deer antler tip cell culture supernatant was subsequently applied to these endothelial inflammatory models, and its protective effects were …

Digital Twin Freshness Maximization In Edge Computing, Jing Li, Jianping Wang, Weifa Liang, Quan Chen, Sajal K. Das, Xiaohua Jia

Computer Science Faculty Research & Creative Works

Mobile Edge Computing (MEC) shifts powerful computing resource provisioning from remote powerful data centers to the edge of core networks. Meanwhile, Digital Twin (DT) has surfaced as a promising technology to provide comprehensive and dynamic descriptions of physical objects in cyberspace with bidirectional and real-time interactions. Moreover, Internet of Things (IoT) devices have contributed abundant, heterogeneous and continuous data from interconnected devices to the explosion of DTs. With technologies evolution, there is an increasing necessity to address the freshness of both DT states and DT data, through timely synchronizations between DTs and their objects in a highly dynamic IoT environment. …

Digital Dialectic: Why Every “Ai-Generated” Work Has A Human Author, Lea Bishop

FIU Law Review

Are ChatGPT and Midjourney tools or creators? Ownership of billions of AI-assisted creative outputs hangs in the balance. Copyright scholars have long debated whether an autonomous artificial intelligence could qualify as an author, but this remains a hypothetical question. Despite widespread application of the term “AI” to software products of the 2020s, autonomously creative artificial intelligence still does not exist. Today’s commercial AI products—such as ChatGPT, Midjourney, Dall-E, Copilot, Gemini, Claude, Suno, Perplexity, and Lumo—are simply the newest generation of computer software. They do not qualify as “artificial intelligence” in either the scientific or science fiction senses. They are mere …

The Accidental Regulator-In-Chief: The Federal Reserve's Path To Power, Jamie Grischkan

FIU Law Review

The independence of the Federal Reserve, long an article of faith among lawmakers, is under attack. From the attempted removal of a member of the Board of Governors to an Executive Order subjecting the Federal Reserve's regulatory and supervisory actions to executive oversight, both the formal legal architecture and informal political norms that have long insulated the central bank from presidential control are being challenged in unprecedented ways. Amidst growing calls to reevaluate the Federal Reserve's mandate and strip the central bank of its regulatory and supervisory authority, recovering the neglected history of the Federal Reserve's role as a regulator …

Owning Data: Semantic Control As Inaccess To Information, Zvikomborero Chadambuka

FIU Law Review

This Article discusses the impacts of the introduction of a data ownership scheme on access to information. It does so with reference to the distinction between data, defined as some representation of information by a specific medium (the syntactic level), and the information itself (the semantic level). With respect to data, it then looks at the difference between standard property rights and intellectual property (IP) rights, similarly assessing impacts on access to information. Private control at the semantic level is bad policy as it effects particularly serious limitations, relative to private control at the syntactic level, on the availability of …

Let’S Talk About The Biological Reality Of Sex, Baby, John Parsi

FIU Law Review

Sex is at the very core of individual identity. It affects the conception of the self and the way others view the individual. Every day, one’s sex may open and close doors, access to communities, and opportunities. Laws that define sex may affirm scientific knowledge and protect people, or threaten to unravel the facts and the reality of sex. A deep unmooring of sex is underway, and this Article aims to halt it. On day one of the current presidential term, January 20, 2025, President Trump signed an Executive Order on “Defending Women from Gender Ideology Extremism and Restoring Biological …

Cruel And Unusual Punishments And The Constitutional Status Of The Idea Of Progress, R. George Wright

FIU Law Review

To this point, we have developed some idea of what progress might have meant to the constitutional Framers, ratifiers, and later judges. We need not attempt the fruitless task of doing any precise head count of the variations of the concrete meaning, perceived likelihood, or value of progress among those parties. Doubtless some persons were more optimistic than others.178 But we need only assume that enough constitutional Framers, ratifiers, and judicial interpreters sufficiently shared any mainstream understanding of progress. Any such constitutional legitimacy of the idea, or the multiple ideas, of progress licenses the language of progress embraced in Trop.

Race, Reparative Justice, And Climate Change-Related Migration, Monica Visalam Iyer

FIU Law Review

The question of how to appropriately respond to migration linked to climate change is increasingly being debated in academia, in government and policy circles, and, crucially, in international legal and climate policy forums. These debates often center on data and on understanding the true numbers of people who might migrate in the context of climate change, and how much of this migration can accurately be linked to climate change, or on the security and logistical concerns associated with responding to this “challenge,” or on the appropriate legal box into which people migrating in this context can be shoved. Too often, …

When Convenience Compromises Rights: How The European Union And Washington State Confront Facial Recognition Risks, Debora Rodriguez Lugo

FIU Law Review

As facial recognition technology (FRT) becomes increasingly embedded in policing, concerns and controversies over the lack of consent, misidentification, and mass surveillance grow. This Comment compares how the European Union (EU) and Washington State (Washington) regulate law enforcement’s use of FRT to mitigate risks to individual rights. The EU governs FRT use through a robust legal framework, including the General Data Protection Regulation (GDPR), the Law Enforcement Directive (LED), and the Artificial Intelligence Act (AI Act), which offer protections against these risks. In contrast, Washington’s pioneering statute, Wash. Rev. Code section 43.386, promotes transparency and limits the use of FRT. …

The Protection Of Geographical Indications Under Comparative Lens: Whether Law Artificially Creates Scarcity Of Goods, Domenico Di Micco

FIU Law Review

The economic principles of supply and demand dictate that market prices are contingent on the conditions under which supply and demand converge. Within this theoretical framework, the concepts of scarcity and abundance assume paramount significance. When goods are scarce, prices tend to escalate, while in cases of abundant supply, prices tend to decline. But what factors determine scarcity and abundance? In many cases, scarcity is inherent to the nature of the commodity (for example, diamonds are rarer than common stones). In other cases, such as geographical indications, scarcity is constructed through the legal denomination associated with the commodity, thereby creating …

Geographical Indications For Agricultural Products: Inconsistencies And Conflicts In Europe And The Global Arena, Lorenzo Bairati

FIU Law Review

Food systems are regulated by a global and hybrid legal framework. In fact, while supranational and international sources play an increasingly important role, private regulators are also becoming more and more involved alongside traditional public policy-makers. Within this context, Geographical Indications (GIs) serve as the main tool in the European Union and beyond to protect quality agri-food products.

This Article aims to explore these instruments in depth in order to analyze several critical aspects from the perspective of global governance, i.e., the networked, hybrid, and diffuse legal space that develops through the participation, negotiation, and strategic interaction between public and …

Comparing Access To Land: Drawing Parallels In Diverse Jurisdictions, Helena Alviar Garcia, Anamaría Muñoz Rincón

FIU Law Review

By exploring the intersection between transitional justice initiatives and transformative constitutionalism, this article proposes that fruitful comparative study covering similarities and differences between diverse definitions of property—challenges and possibilities of accessing it and the main characteristics of the disputes over it—in four jurisdictions can be advanced. A close examination of the classic liberal paradigm framing the transitional process reveals the ways in which a progressive and justice-driven understanding of property falls short in all the countries considered. To examine this, we look at how property clauses, substantively and procedurally, are construed in transformative constitutions sitting at the heart of the …

Contracting For Innovation In The Global South: Empirical Evidence From Brazil, Pablo Marcello Baquero

FIU Law Review

As innovation cycles accelerate, companies seeking to remain at the forefront of the knowledge economy increasingly partner with sophisticated firms to co-create innovation. These collaborations involving pervasive uncertainty are structured through hybrid contractual arrangements that combine features of market-based independence with those of the close coordination typical of the firm. To date, contracting for innovation has been examined primarily in the context of the Global North. In the United States, the literature has focused on the governance mechanisms that parties employ to continuously define their obligations and mitigate opportunism amid profound uncertainty. In Europe, scholarship on contractual networks or organizational …

The Italian Rice Production: Between Tradition And Globalization, Bianca Gardella Tedeschi

FIU Law Review

The Article examines the Italian rice sector as a case study in how law mediates the tensions between territorial agricultural traditions and the pressures of globalization. Focusing on the rice-producing districts of Piedmont and Lombardy, the Article argues that the resilience of Italian rice production cannot be explained solely by agronomic or economic factors. Rather, it depends on a dense legal and institutional framework that structures water governance, quality control, market organization, and contractual relations across the supply chain.

The Article develops three principal claims. First, it shows that the competitiveness of Italian rice production rests on an integrated model …

The New European Union Regulation On Geographical Indications For Craft And Industrial Products And The Protection Of "Lace Of Cantù": A Work In Progress, Barbara Pozzo

FIU Law Review

Regulation (EU) 2023/2411 of the European Parliament and of the Council of 18 October 2023 has introduced the protection of geographical indications for craft and industrial products. The contribution aims at investigating how the Regulation may have implications in the fashion world. In particular, it will focus on a particular case study undertaken in Northern Italy, concerning the possibility of protecting the “Lace of Cantù” through a geographical indications for craft.

The Making Of Egyptian Cotton: An Alternative Narrative Between Empire And Global Capital, Dina I. Waked

FIU Law Review

Egyptian cotton has become a celebrated brand. Referring to cotton as “Egyptian” signals a certain quality, luxury, and durability. Egyptian cotton has, thus, become its own trademark, a signifier of value, and a symbol of national heritage. This image is carefully curated. It is now protected under a licensing scheme of branding and marketing that assures that fraudulently claimed “Egyptian cotton” does not benefit from the added value this geographic location ascribes to it. The Egyptian Cotton Association was thus created 2005 to license and accredit the brand. Part of the curation of the brand image is a historical narrative …

Virtual Harm, Real Consequences: Constitutional Justifications For Criminalizing Ai-Generated Child Pornography, Adam Abdin

FIU Law Review

Advances in artificial intelligence (AI) have enabled the creation of hyper-realistic child sexual abuse images without any real child involved. These AI-generated depictions pose a unique challenge: they replicate the most pernicious form of pornography—child pornography—while potentially being claimed as “speech” immune from regulation. This paper argues that it is both constitutionally permissible and morally imperative to criminalize AI-generated child pornography. This article presents two doctrinal pathways to justify a ban. First, such content can be treated as unprotected speech under existing First Amendment exceptions. Courts have long held that child pornography and obscenity lie outside First Amendment protection, and …

A Four-Step Thermocatalytic Route For Converting Co2 Into High-Purity Oxalic Acid, Hao Feng, Muhammad Kashif Khan, Lei Li, Hongyan Ma, Xinhua Liang

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

This research outlines a four-step methodology for transforming CO₂ into high-purity oxalic acid. CO2 was first sequestered as KHCO₃ through its reaction with aqueous KOH, followed by hydrogenation using a supported AgPd/CNT catalyst in a batch reactor at an initial H₂ pressure of 60 bar and a temperature of 150°C. The formate yield reached 91.8% at optimum conditions. Potassium formate in the solid state was thermally coupled in the presence of KOH at 400°C under N2 flow, yielding potassium oxalate of up to 76% yield. The final step was the selective precipitation of potassium oxalate with ferrous …