Digital Commons Network^™

Nanoparticle Carriers Enhance The Prophylactic Antiviral Effects Of Dsrna In Vitro And Ex Vivo, Shayne Oberhoffner, Stephanie Dewitte-Orr, Starla Richardson, Leah Haile, Dominique Daniels, Erin Cooper, Aizah Ijaz, Janet Velasquez Perez, Mathilde Peruzzi, Bertrand Collet, Paul Craig, Kristof Jenik

Theses and Dissertations (Comprehensive)

Aquaculture now outpaces traditional capture fisheries as the world population and demand for sustainable protein sources increases. Wild and farmed species are increasingly susceptible to pathogen spread as global temperatures rise and stocking densities increase. Despite the devastating losses experienced by aquaculture due to viral infections, there remain few effective prophylactic antiviral therapeutics. Long double-stranded (ds)RNA is a uniquely viral molecule produced by nearly all viruses during their replication cycle, and its detection by salmonids like rainbow trout (Oncorhynchus mykiss) and chinook salmon (Oncorhynchus tshawytsha) leads to the establishment of a defensive antiviral state. Previous in vitro studies demonstrated a …

Adapting To Uncertainty: Effects Of Environmental Instability On Zebrafish Behaviour, Britney Sekulovski

Theses and Dissertations (Comprehensive)

This thesis addresses how animals cope with unpredictability by testing how environmental stability changes the behaviour of zebrafish (Danio rerio) in two complementary experiments. In Experiment 1, fish lived for three months in either a Dynamic environment (water temperature, feeding times, habitat complexity, group size, and membership fluctuated) or a Stable environment (all factors constant). Across seven behavioural assays, measuring individual behavioural differences, collective movement, social memory, and information use, Dynamic condition fish were found to be more sensitive to social cues and more likely to conform to recent social information, independent of the quality of the information …

Minority Stress And Drug Use Among 2slgbtq+ Canadians, Robert Chin-See, Todd Coleman

Theses and Dissertations (Comprehensive)

Background: Several social and environmental factors influence drug use behaviors and contribute to frequent drug use among Two-Spirit, Lesbian, Gay, Bisexual, Transgender, Queer, and other (2SLGBTQ+) individuals. The purpose of the current study was to examine the relationship between the minority stress, drug use, and other socio-ecological factors.

Methods: This study employed structural equation modelling on data (2021—2022) from a nationally representative pan-Canadian survey (N = 1542) on 2SLGBTQ+ health to examine the association between minority stress, drug use, and relevant socio-ecological predictors. A separate mediation analysis was conducted and controlled for socio-demographic characteristics.

Results: SEM results showed parsimonious fit …

Envisioning The Role Of Community-Owned Stores & Aligning Federal Food Policies: A Participatory Approach To Food Security And Food Sovereignty In Sambaa K’E, Denendeh (Northwest Territories, Canada), Narayan Subramoniam

Theses and Dissertations (Comprehensive)

Northern Indigenous communities have relied on traditional food systems for meaningful, nutritious diets since time immemorial. But many Indigenous communities in remote northern regions of Canada still face disproportionately elevated levels of food insecurity due to climate change radically altering the availability for traditional foods, colonial food policies imposing Western diets, and the high costs of transporting store-bought foods. Extreme weather events such as wildfires further isolate fly-in remote communities increasing both the costs of transporting store-bought foods and the difficulties of harvesting traditional foods. There are many examples of community-based initiatives for supporting traditional and locally grown foods, however, …

Investigating The Impact Of Winter Exposure To Natural Environments On Perceived Health And Well-Being Using Geographic Ecological Momentary Assessment: A Case Study At Arrowhead Provincial Park, Faith M. Laing

Theses and Dissertations (Comprehensive)

This study examined how winter exposure to specific natural environments influenced perceived health and well-being outcomes using Geographic Ecological Momentary Assessment (GEMA) in Arrowhead Provincial Park. Studies performed in the wintertime are limited, as is our understanding of how specific park features and/or activities impact health and well-being. To address this, GEMA was used with a video component to capture participants’ real-time experience and emotional responses in specific park locations defined by polygon boundaries. Two surveys were administered through participants mobile devices, one being an in-situ engagement survey triggered by entering a bounded location, which included a video and …

Injury To Insight: Exploring The Influence Of Media On Acl Rehabilitation Experiences Of Female Soccer Players, Chynna Ho-Young Cadogan, Jill Tracey

Theses and Dissertations (Comprehensive)

Participation in soccer inherently carries a risk of injury, with female athletes facing a significantly higher susceptibility to anterior cruciate ligament (ACL) injuries (Campbell et al., 2014; Le et al., 2025; Silvers-Granelli, 2021). The increasing participation in women’s soccer, coupled with the growing demand for its consumption through spectatorship, has contributed to a rise in ACL injuries, and increase in media coverage on this phenomenon (Parsons et al., 2021). Understanding how media narratives surrounding ACL injuries and recovery may influence rehabilitation experiences can educate coaches, mental performance consultants, athletic therapists, and female soccer players to better understand and navigate ACL …

Autism And Homelessness: An Intersectional Case Study In Kitchener-Waterloo, Ontario, Nicole J. Mcdonald

Theses and Dissertations (Comprehensive)

Homelessness is a growing crisis in Canada, with literature suggesting autistic traits as over-represented within this population. Literature addressing intersectional experiences of autism is emerging, however there are gaps in the research surrounding intersectional experiences of autism and homelessness. Research suggests that autistic individuals may be more vulnerable to experiencing homelessness and face difficulties in exiting homelessness. This qualitative case study utilizes a Disability Justice framework to explore intersectional autistic experiences of homelessness, social service usage, and suggests recommendations on improving support for autistic individuals at risk of and experiencing homelessness. Four autistic participants with experience of homelessness and accessing …

The Phone Eats First: Reconfiguring Cultural Capital And Performing Taste On Tiktok’S #Torontoeats, Annie M. Willick

Theses and Dissertations (Comprehensive)

This study investigates how TikTok reconfigures cultural capital through the visual commodification and performative display of Toronto’s food culture using the hashtag “#TorontoEats”. Through a digital ethnographic multimodal critical discourse analysis, my research considers Bourdieu’s (1984) definition of cultural capital as the guiding definition of distinction, status, and personal taste. This analysis considers how cultural capital manifests through algorithmic engagement, adherence to platform norms, and TikTok’s multimodal format that blends video, sound, text, and gesture to entice audiences. Findings suggest that mundane food practices and activities are transformed into conspicuous commodities on TikTok, where creators position themselves as tastemakers and …

At A Crossroads: Crisis, Vulnerability, And The Possibility Of Transformation Of Nature-Based Tourism In Canada, Brooklyn Rushton

Theses and Dissertations (Comprehensive)

We live in an era shaped by a global polycrisis, where climate change, pandemics, economic shocks, geopolitical tensions, and social inequities are converging to create complex, cascading, and compounding risks. For Canada’s nature-based tourism sector, situated at the nexus of social and ecological systems, the polycrisis both amplifies the vulnerabilities of tourism and highlights tourism’s role in perpetuating global risks. Recognizing this duality, this dissertation examines how crises amplify systemic vulnerabilities while also acting as leverage points for transformative change in Canada’s nature-based tourism sector, drawing on geography, systems thinking, resilience theory, regenerative tourism, and futures thinking scholarship.

The three …

Science Fiction Cinema And The Technological Sublime: Spectacle And The Infinite From Early Cinema To Digital, David Jackson Dr.

Theses and Dissertations (Comprehensive)

This dissertation examines how science fiction cinema constructs and reimagines the technological sublime in the twentieth century: the experience of awe, terror, and admiration provoked by human-made power and scale. Drawing on the philosophical foundations of the sublime in Edmund Burke and Immanuel Kant and extending through Leo Marx’s and David E. Nye’s theorization of the technological sublime, I propose an aesthetic mode in which representation inflected with affect translates technological spectacle into examinations of humanity’s role and agency in the face of overwhelming technologized worlds and in some cases, even the universe itself.

Through three distinct historical periods …

Implementation Of A 3-Dimensional Hydrodynamic Numerical Model On A Large Northern Lake, Kirin Lorente

Theses and Dissertations (Comprehensive)

Climate change is impacting high latitude regions disproportionately more than those at a lower latitude. With polar lakes being highly sensitive to changes in the climate, shifts in lake ice dynamics and hydrodynamics are indicators of such changes in regional and global climates. These changes impact future seasons in a positive feedback loop, where changes in winter ice cover impact open water nutrients levels and lake thermal structure. This highlights the importance for long-term monitoring. Despite the abundance of lakes distributed across Northern Canada, there has been limited research conducted on these sentinels of climate change.

Specifically, Great Bear Lake …

Cognitive Load Classification Using Functional Near-Infrared Spectroscopy, Pratham Shah

Theses and Dissertations (Comprehensive)

This thesis investigates the classification of cognitive load using functional near-infrared spectroscopy (fNIRS) signals recorded during an N-back working memory task. The study introduces a novel short-channel correction layer designed to suppress superficial physiological noise adaptively, addressing limitations of traditional General Linear Model (GLM) based regression. A single participant dataset comprising 69 validated sessions was analyzed using both conventional machine learning and deep learning approaches. Traditional classifiers: Linear Discriminant Analysis (LDA), Support Vector Machines (SVM), Random Forests, and Gradient Boosting were first evaluated using statistical features (mean, variance, peak, and slope). Among these, Gradient Boosting achieved the highest accuracy (55.6%), …

Unveiling Othering Experiences In Multiethnic Families: Narratives Of Identity And Belonging Among White/Hispanoamerican Women, Maria-Esther Wood

Theses and Dissertations (Comprehensive)

This dissertation explores the lived experiences of multiethnic Hispanoamerican women as they navigate identity, belonging, and familial othering within the context of multiethnic family systems. Using qualitative narrative inquiry, the study centres the voices of nine women residing in Ontario, each with one white parent and one Hispanoamerican parent, ranging in age from 19 to 65. Guided by Dewey’s three-dimensional model of narrative analysis, the research explores how personal stories reflect broader patterns of othering and belonging, the central research question asks: What specific forms of othering related to identity and belonging—inclusive of discrimination and racist treatment—do multiethnic Hispanoamerican women …

A Contribution To Constructing A Theory And Model Of Social Work Leadership, Cheri Darlene Bilitz

Theses and Dissertations (Comprehensive)

Few schools of social work provide formal leadership education and training for emerging social workers—the research topic under exploration was how social work leaders constructed their leadership style. The purpose of the study was to develop a model of social work leadership through understanding leaders’ journeys into leadership and the contextual factors that shaped their leadership. Participants shared the qualities they believed were paramount for leading today and into the future. Seeing schools of social work as leadership incubators for emerging social workers, participants shared their suggestions for scaffolded leadership curriculum. The methodological approach for this research study was constructivist …

The Forgotten Carers: A Study Of The Lived Experiences Of Chinese Canadians Caring For A Family Member With Borderline Personality Disorder (Bpd/Fbpd), Judy Y.F. Wu

Theses and Dissertations (Comprehensive)

There is a fair amount of literature on Borderline Personality Disorder (BPD); however, it still lags behind research on other major mental illnesses such as depression and schizophrenia (Furnham et al., 2015). Similarly, while there has been ample research on caring from various perspectives; little has been explored regarding caring for individuals with BPD. Research on Chinese Canadian families caring for patients with BPD is even more scarce. This study explored the lived experiences of Chinese Canadians caring for family members diagnosed with BPD (FBPD) in the Greater Toronto Area (GTA), Ontario, Canada. BPD is characterised by “interpersonal hypersensitivity, affective …

A Novel Federated Llm Framework For Distributed Traffic Modelling In Intelligent Transportation Systems, Seerat Kaur

Theses and Dissertations (Comprehensive)

Intelligent transportation systems (ITS) depend on accurate traffic prediction to support congestion management, infrastructure planning, and real-time operational decisions. Despite substantial progress in data-driven forecasting, several challenges continue to limit practical deployment: traffic data is distributed across independent regional authorities, making centralized aggregation infeasible, standard federated aggregation strategies ignore traffic-specific characteristics that meaningfully affect model quality, and existing models produce only numerical outputs without interpretable reasoning that urban planners can act upon. This thesis addresses these challenges through four contributions that collectively advance privacy-preserving, explainable, and scalable traffic forecasting.

The first contribution provides a systematic review of 129 peer-reviewed publications, …

Three Essays On Corporate Bond Short Selling, Climate And Credit Risks, Manisha Thapa

Theses and Dissertations (Comprehensive)

This dissertation comprises three essays investigating topics on Corporate Bond Short Selling, Climate and Credit Risks.

The first essay addresses the question: Does climate risk influence bond short selling? We address this question by studying how climate risk influences the relationship between corporate bond short selling and subsequent credit default swap (CDS) spreads. We find that future CDS spreads are strongly related to bond short selling for the high climate risk firms. In particular, our fixed effects triple difference-in-differences (DiD) regressions show that sensitivity of subsequent CDS spreads to lagged bond short selling is significantly higher for firms with high …

Cultivating Diversity In Sustainable Food Systems: Black Farming And Lived Experience In Rural Southern Ontario, Kadeem Jerofy Morgan-Adamson Mr.

Theses and Dissertations (Comprehensive)

This research examines the lived experiences of Black food growers in rural Southern Ontario to understand how their perspectives challenge dominant narratives of rurality and inform broader discussions on food sovereignty in Canada. Grounded in postcolonial theory, the study highlights how historical dispossession and persistent inequities shape the access of Black communities to land and resources. Using a mixed-methods approach that includes surveys, semi-structured interviews, and reflexive journaling within a community-based research framework, the study documents the barriers Black food growers face. These include limited land access, insufficient funding, inadequate training pathways, and experiences of racial isolation in rural contexts. …

Taylorkan-Vit: Parameter-Efficient Vision Transformers For Medical Image Classification, Kaniz Fatema, Dr. Emad Mohammed, Dr. Sukhjit Singh Sehra

Theses and Dissertations (Comprehensive)

Effective and interpretable classification of medical images remains a critical challenge in computer-aided diagnosis, particularly in data-scarce and resource-constrained clinical settings where traditional deep learning models prove impractical. This study addresses the fundamental barrier to Vision Transformer adoption in medical imaging—massive parameter counts and data requirements—through a systematic two-phase methodology. Phase 1 evaluates three spline-based Kolmogorov–Arnold Network (KAN) variants to identify the optimal nonlinear approximation function for parameter-efficient medical image classification: SBTAYLOR-KAN (B-splines with Taylor series), SBRBF-KAN (B-splines with Radial Basis Functions), and SBWAVELET-KAN (B-splines with Morlet wavelets). Comprehensive experiments across brain MRI, chest X-rays, and tuberculosis datasets—without any image …

Investigating The Immunostimulatory Potential Of Dsrna-Silk Nanoparticle Complexes In Melanoma, Samuel J. Peters

Theses and Dissertations (Comprehensive)

The rate of resistance to immune checkpoint inhibitor treatment in metastatic melanoma is quite high, with an overall rate of 70%. Melanoma achieves these high rates of resistance by suppressing the immune response in the tumour microenvironment (TME), making them immunologically “cold”. The type 1 interferon response could be leveraged to initiate immune responses in melanoma, making their “cold” TMEs “warm” again. Double-stranded ribonucleic acids (dsRNAs) are potent activators of an innate immune response; however, they are susceptible to degradation by nucleases present in the body and need a carrier. Silk nanoparticles (SNPs) are an ideal drug-delivery platform as they …

“My Voice Is Trauma, My Voice Is Healing:” A Feminist, Trauma-Informed Embodied Study On The Impact Of Gender-Based Violence In Classical Music Communities, Sarah Pearson

Theses and Dissertations (Comprehensive)

This Social Work doctoral dissertation explores the impact of gender-based violence (GBV) in classical music communities on survivor-artists. This is an intersectional feminist, trauma-informed, embodied study that draws on these three theoretical concepts to conceive of classical music as an institution of both colonial patriarchal power and a site of spirituality and meaning-making. The issue of systemic GBV in the performing arts has been a focus of headline news and sensational celebrity stories in the last decade following the MeToo hashtag and is slowly gaining some attention in academic research.

For this qualitative study, the sample consisted of 14 participants …

Picturing Your Goals: Examining Imagery Perspective And Self-Concordance In Goal Motivation, Cana J. Reuber

Theses and Dissertations (Comprehensive)

Mental imagery is often used as a strategy to increase motivation and support goal pursuit, but it remains unclear when different forms of imagery are most effective. Prior work suggests that adopting a third-person imagery perspective may enhance goal striving by promoting more abstract, identity-relevant processing. In line with this work, we predicted that third-person imagery would be most beneficial for self-concordant goals. The present research tested this prediction across three studies. In Study 1 (N = 273), participants identified a personal goal, visualized themselves pursuing and attaining it from either a first- or third-person perspective, and reported their …

An Examination Of Speech Motor Control And Auditory Processing In Attention Deficit Hyperactivity Disorder (Adhd), Rita Bishai

Theses and Dissertations (Comprehensive)

Fluent speech production is achieved through a relative weighting of feedback and feedforward motor control systems. These systems are thought to be responsible for the online correction of vocal errors and initiating speech, respectively. The relative weighting of these motor control systems has been shown to differ under conditions of high attentional load and across individual differences in sensory acuity. However, research has yet to examine speech motor control in a population with clinical attentional and sensory processing differences, such as those with Attention-Deficit Hyperactivity Disorder (ADHD). The studies in this thesis aimed to examine how ADHD traits relate to …

The Power Of Letting Go: The Role Of Goal Adjustment Capacities Across Future And Daily Perspectives Of Chronic Illness, Alexandra Dagher, Meaghan Barlow

Theses and Dissertations (Comprehensive)

Goal adjustment capacities are self-regulatory processes that protect psychological well-being by allowing individuals to disengage from unattainable goals and reengage in new attainable ones. Although research has shown that these capacities are beneficial in the context of chronic illness, little is known about how their effectiveness may differ across various aspects of the chronic illness experience. The present research consisted of two distinct yet complementary studies examining the role of goal adjustment capacities in two chronic illness contexts. Study 1 (N = 149) prompted participants to imagine the future progression of a chronic illness, whereas Study 2 (N …

Permafrost Microtopography And Active Layer Hydrology In The Western Canadian Arctic, Tobias L. Leonhard

Theses and Dissertations (Comprehensive)

The growing interest in Arctic regions will likely increase the use of nuclear energy in the Arctic. While this energy source has a high potential to improve economic opportunities in the Arctic, it also increases the release of radioactive material (radionuclides). Radionuclides are already found in the Arctic and are traced back to natural as well as anthropogenic sources. Water is one of the dominant transport vectors for solutes such as radionuclides or other contaminants. Therefore, improving our understanding of Arctic hydrology is important for assessing future environmental risks such as the release of radionuclides. Topographic and microtopographic features are …

Analysis Of Alternative Oxidase In Non-Angiosperm Plants, Anissa M. Francis

Theses and Dissertations (Comprehensive)

Alternative oxidase (AOX) is a mitochondrial terminal oxidase that provides an alternative pathway for electron transport, allowing plants to maintain respiratory flexibility under environmental stress conditions. While AOX has been extensively studied in angiosperms (flowering plants), little is known about its distribution and conservation in non-angiosperms. Based on gaps identified in the literature, this thesis investigated the distribution of AOX across non-angiosperm plant lineages. Although AOX is present in many green algae and is therefore considered to be an ancient protein that originated before the existence of non-angiosperm plants, it remains unclear whether the protein is uniformly distributed across these …

The Effects Of Appearance Change And Partial Face Visibility On Eyewitness Identification, Raina-Lynn A. Brock M.A., Judy Eaton Ph.D.

Theses and Dissertations (Comprehensive)

There is limited research examining the possibility of a temporary appearance change (e.g. a black eye) between exposure to a perpetrator at the time of a crime and later identification attempts by eyewitnesses. Across two experimental studies, this research examines how eyewitness identification decisions are impacted by an appearance change and how lineup procedures can influence eyewitness accuracy. Study 1 examined how a transient facial feature, a black eye, affects the accuracy of eyewitnesses’ identification decisions, while manipulating the severity of the black eye (prominent bruising, faded bruising, no bruising). Participants (N=403) were exposed to a 43-second mock crime video …

Finding Aid For The Deavours Family Collection

Archives & Special Collections: Finding Aids (alphabetical)

The Deavours Family Collection contains genealogical information about the Deavours and related families.  It also holds material related to Stone Deavours, a lawyer, who served as University of Mississippi Law School Dean from 1930 to 1932.  The collection also includes two nineteenth-century ledgers regarding Garlandsville, Mississippi and the journal of an unidentified Alabama dating from 1860 to 1874.

Brewed Differently: Comparing Subheading Use In Embase And Medline, Cynthia M. Schmidt, Danielle Westmark

Posters and Presentations: Leon S. McGoogan Health Sciences Library

This project compared MEDLINE and Embase indexers' use of therapy subheadings and discusses the implications for literature searching. Objectives Our long experience with MEDLINE searching and attendance at NNLM-sponsored PubMed training sessions taught us to depend on specific patterns of subheading use by MEDLINE’s indexers. For instance, we learned to expect that drug trials would be indexed with a drug heading combined with a therapeutic use subheading. Our library licensed EMBASE in 2012. We soon began to suspect that subheading application was not as predictable in EMBASE as it was in MEDLINE. We wanted the recommendations we provide novice EMBASE …

A Tribal Hermeneutical Reading Of The Creation Narrative In Genesis 1:26-28, Enolyne Lyngdoh

The Asbury Journal

No abstract provided.