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Presidential Search Committee Minutes, Clemson University Board Of Trustees, 2026 January 16, Clemson University Board Of Trustees Jan 2026

Presidential Search Committee Minutes, Clemson University Board Of Trustees, 2026 January 16, Clemson University Board Of Trustees

Minutes

No abstract provided.


Ai-Enabled Decision-Support Systems In The Joint Targeting Cycle: Legal Challenges, Risks, And The Human(E) Dimension, Jessica Dorsey, Marta Bo Jan 2026

Ai-Enabled Decision-Support Systems In The Joint Targeting Cycle: Legal Challenges, Risks, And The Human(E) Dimension, Jessica Dorsey, Marta Bo

International Law Studies

Israel’s military campaign in Gaza as well as ongoing conflicts in Ukraine, Yemen, Iraq, and Syria include the reported military use of AI-enabled decision-support systems (AI-DSS) within the joint targeting cycle (JTC). These tools use AI techniques to collect and analyze data, provide information about the operational environment, and make actionable recommendations with the aim of aiding military decision-makers in evaluating factors relevant to legal compliance, such as taking precautions and ensuring proportionality in attacks. These systems are often touted as being simply a human aid and, as such, have flown largely under the radar regarding regulation as they are …


Where Americans Get And Trust Political Information: Traditional Media Leads, Social Media Grows, Ai Emerges, Hwayong Shin Jan 2026

Where Americans Get And Trust Political Information: Traditional Media Leads, Social Media Grows, Ai Emerges, Hwayong Shin

Weidenbaum Center Survey (WCS) Reports

Where do Americans turn for political information—and which sources do they actually trust? As traditional news organizations struggle with declining public trust (Brenan 2025; Ladd 2012), social media platforms (e.g., Facebook, Instagram, X) and artificial intelligence (AI) tools (e.g., ChatGPT, Gemini, Copilot) are increasingly stepping into the information space (Bode 2016; Podimata & Cen 2025). Yet little is known about how these sources compare in citizens’ minds. This question matters because a well-functioning democracy depends not just on the availability of information, but on which sources individuals use and trust to support informed political judgments (Lupia & McCubbins 2019; Soroka …


College Students' Barriers To Mental Health Support Services: A Practitioner's Perspective, Rebecca C. Johnson Jan 2026

College Students' Barriers To Mental Health Support Services: A Practitioner's Perspective, Rebecca C. Johnson

Dissertations, Theses, and Projects

The purpose of this study was to identify barriers to accessing mental health support for college students from the perspective of college faculty counselors. In 2022, research indicated that over 60% of college students met the criteria for one or more mental health conditions (Lipson et al., 2022), though data published in the same year revealed that practitioners employed at colleges and universities are only supporting an average of 12.2% of the student population (Bruns et al., 2023). While college counseling centers have reported increasing usage rates, there remains a gap in the number of students utilizing services versus those …


Cold Atmospheric Plasma For Prostate Cancer Therapy—Potential For Clinical Translation, Shengxin Zhang, Janith Wanigasekara, Daniela Boehm, James F. Curtin, Paula Bourke, Tao Zhang, Gemma K. Kinsella Jan 2026

Cold Atmospheric Plasma For Prostate Cancer Therapy—Potential For Clinical Translation, Shengxin Zhang, Janith Wanigasekara, Daniela Boehm, James F. Curtin, Paula Bourke, Tao Zhang, Gemma K. Kinsella

Research Outputs: 2025-Present

Cold atmospheric plasma (CAP) has potential as a new cancer treatment tool due to its room temperature biocompatibility and possible cancer cell selectivity with low side effects. This review examines the current research stage of CAP therapy for Prostate Cancer (PCa) treatment with a focus on CAP device standardization and CAP therapy clinical translation. The current CAP preclinical data is explored through the lens of PCa cellular response, PCa cells selectivity, CAP treatment type and CAP combination therapies. Finally, building on the current preclinical data, this review proposes the potential clinical application methods of CAP at different PCa stages to …


Optimal Murine Cd4+ T Cell Priming By Mrna-Lipid Nanoparticle Vaccines Requires Endogenous Antigen Processing, Julia E. Rood, Suh Kyung Yoon, Mary K. Heard, Stephen D. Carro, Emma J. Hedgepeth, Mary E. O'Mara, Michael J. Hogan, Nhu Le, Hiromi Muramatsu, Kieu Lam, Petra Schreiner, Coral Kasden, Hansell H. Stedman, Ryan A. Langlois, James Heyes, Norbert Pardi, Laurence C. Eisenlohr Jan 2026

Optimal Murine Cd4+ T Cell Priming By Mrna-Lipid Nanoparticle Vaccines Requires Endogenous Antigen Processing, Julia E. Rood, Suh Kyung Yoon, Mary K. Heard, Stephen D. Carro, Emma J. Hedgepeth, Mary E. O'Mara, Michael J. Hogan, Nhu Le, Hiromi Muramatsu, Kieu Lam, Petra Schreiner, Coral Kasden, Hansell H. Stedman, Ryan A. Langlois, James Heyes, Norbert Pardi, Laurence C. Eisenlohr

College of Life Sciences Faculty Papers

Lipid nanoparticle (LNP)-encapsulated nucleoside-modified mRNA vaccines elicit robust CD4+ T cell responses, yet the mechanisms underlying this T cell priming remain unknown. Antigens presented to CD4+ T cells on major histocompatibility complex class II (MHC II) are traditionally acquired by antigen presenting cells (APCs) from extracellular sources. Here we show that vaccine specific CD4+ T cell responses instead rely on antigen directly expressed within APCs, without extracellular transit. Murine APCs treated with mRNA-LNP vaccines activate T cells more efficiently when presenting antigen produced internally, rather than acquired externally. Immunization with mRNA-LNP vaccines engineered to inhibit antigen expression in APCs results …


Institutional Practices Drive Antibiotic Variability In Neonatal Intensive Care Units: Baseline Evidence To Inform National Stewardship Interventions In Oman, Abdullah Alqayoudhi, Manoj Malviya, Sathiya Murthi, Mohammed Rasik Nv, Adil Said Al-Wahaibi, Raya Al-Habsi, Said Al-Balushi, Talal Alwardi, Agha Hatif Shamsi, Halah Bait Raidan, Aamera Al-Majrafi, Preethi Kiran, Eyad Hani Abu Abu Alhaijaa, Kawther Al Amri, Khalfan Al Abdali, Mohammed S. Al Reesi, Nasser Al-Shafouri, Amal Al-Jabri, Sachin Shah, Said Al-Kindi, Zubair H. Aghai, Mohammed Al-Yahmadi, Amal Al-Maani Jan 2026

Institutional Practices Drive Antibiotic Variability In Neonatal Intensive Care Units: Baseline Evidence To Inform National Stewardship Interventions In Oman, Abdullah Alqayoudhi, Manoj Malviya, Sathiya Murthi, Mohammed Rasik Nv, Adil Said Al-Wahaibi, Raya Al-Habsi, Said Al-Balushi, Talal Alwardi, Agha Hatif Shamsi, Halah Bait Raidan, Aamera Al-Majrafi, Preethi Kiran, Eyad Hani Abu Abu Alhaijaa, Kawther Al Amri, Khalfan Al Abdali, Mohammed S. Al Reesi, Nasser Al-Shafouri, Amal Al-Jabri, Sachin Shah, Said Al-Kindi, Zubair H. Aghai, Mohammed Al-Yahmadi, Amal Al-Maani

Department of Pediatrics Faculty Papers

Background: Antibiotic overuse in Neonatal Intensive Care Units (NICUs) is a major contributor to antimicrobial resistance and adverse neonatal outcomes. This study aims to evaluate baseline antibiotic utilization (AU), identify factors influencing variability, and assess the impact of neonatal characteristics and sepsis incidence. Methods: A multicenter retrospective analysis examined AU in seven NICUs from 2019 to 2023, involving 25,532 neonatal admissions during national antibiotic stewardship program implementation. Data encompassed neonatal clinical parameters, sepsis incidence, and AU metrics, including days of therapy (DOT) per 1000 patient-days. Statistical analyses included correlation assessments and multivariate regression to identify determinants of antibiotic use. Results: …


The Ethical Limits Of Physician Autonomy In Reproductive Medicine, Isabel Martens Jan 2026

The Ethical Limits Of Physician Autonomy In Reproductive Medicine, Isabel Martens

Honors Theses

In vitro fertilization is a relatively new medical practice that helps people who face infertility be able to reproduce. Reproductive medicine providers face ethical dilemmas often in their field, only some of which have standards of care. There are questions in the medical landscape pertaining to physician autonomy versus patient autonomy, which heavily apply to reproductive medicine providers. Patient autonomy is highly valued in medical ethics; however, physician autonomy should also be considered. When a physician decides who can and cannot reproduce, ethical considerations must be followed to maintain the practice of reproductive autonomy. Limited policies exist that manage reproductive …


Elevated Trna Halves In Olfactory Epithelial Cells Of Patients With Schizophrenia, Justin T. Gumas, Megumi Shigematsu, Karin E. Borgmann-Winter, C. G. Hahn, Yohei Kirino Jan 2026

Elevated Trna Halves In Olfactory Epithelial Cells Of Patients With Schizophrenia, Justin T. Gumas, Megumi Shigematsu, Karin E. Borgmann-Winter, C. G. Hahn, Yohei Kirino

Computational Medicine Center Faculty Papers

Schizophrenia patients' olfactory epithelial cells contain abundant immune-activating tRNA fragments, linking small RNA biology to inflammation and suggesting avenues for diagnostics.


Usa V. Victorious Minter Jan 2026

Usa V. Victorious Minter

2026 Decisions

USDC for the Middle District of Pennsylvania


Usa V. Kyle Stevens Jan 2026

Usa V. Kyle Stevens

2026 Decisions

USDC for the District of Delaware


Human Capital And Development, Philippe Aghion, Ingvild Almås, Costas Meghir Jan 2026

Human Capital And Development, Philippe Aghion, Ingvild Almås, Costas Meghir

Cowles Foundation Discussion Papers

Human capital is central to efforts to promote growth, convergence, and the elimination of poverty. Drawing on seminal macroeconomic frameworks by Nelson-Phelps, Lucas, and subsequent developments, alongside macro and microeconomic evidence, the chapter examines the role of human capital in driving innovation and growth, emphasizing how different types of human capital matter at different stages of development, and discussing obstacles to accumulation and evidence from policy interventions.


20260113: Physical Education And Wellness, 1970-1997, College Of Education And Professional Development Jan 2026

20260113: Physical Education And Wellness, 1970-1997, College Of Education And Professional Development

Guides to University Archives

These items include materials from the College of Education and Professional Development at Marshall University from 1970-1997. Items were received in the 1980s and were processed in 2026 and include notable materials from two separate areas... the first one is a WMUL & closed circuit television services, and the second set of materials in this collection is a newsletter titled Well/Fit News that ranges from 1993-1997. Please download the finding aid for a full list of contents.


Distribution System Reliability Evaluation Considering Protection Coordination Using Petri Nets, Rani Kumari, Bhukya Krishna Naick Jan 2026

Distribution System Reliability Evaluation Considering Protection Coordination Using Petri Nets, Rani Kumari, Bhukya Krishna Naick

Turkish Journal of Electrical Engineering and Computer Sciences

Maintaining reliable and high-quality power delivery becomes increasingly complex with expanding power grids. The lack of protection coordination poses a significant threat, compromising overall system reliability. This research addresses this challenge by proposing a method for coordinating protective devices within the distribution system, specifically during network faults. The proposed approach utilizes a stochastic timed Petri net (STPN) based methodology to model protective device coordination across various fault scenarios. This technique effectively captures the dynamic behavior and interactions of protective equipment, allowing for the anticipation of potential disturbances. This proactive insight facilitates preventative measures to address prewarning situations, thereby preventing cascading …


Book Review: The Politics Of War And Peace: A Survey Of Thought, Isaiah Wilson Iii Jan 2026

Book Review: The Politics Of War And Peace: A Survey Of Thought, Isaiah Wilson Iii

Parameters Bookshelf – Online Book Reviews

Authors: Abbott A. Brayton and Stephana J. Landwehr

Reviewed by: Dr. Isaiah “Ike” Wilson III (colonel, US Army retired); professor of practice, Arizona State University; and president emeritus, Joint Special Operations University

Spanning centuries of political and philosophical reflection, Brayton’s work explores how thinkers from ancient times to the modern era have grappled with the moral and strategic dilemmas of war and peace. Through a rich tapestry of ideas, the book reveals the enduring tensions between justice, power, and diplomacy. It’s an essential guide for understanding how past wisdom continues to shape contemporary debates on conflict and resolution.

Copyright: ©2026 …


Butte Priority Soils Operable Unit (Bpsou) Data Summary Report (Dsr) Statement Of Authenticity Updates, Mike Mcanulty Jan 2026

Butte Priority Soils Operable Unit (Bpsou) Data Summary Report (Dsr) Statement Of Authenticity Updates, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Prevalence Of Depression Among Doctors In General Hospitals Of Basrah City Center During The Covid-19 Pandemic, Riham Sabri Saleh, Amaleed Kadhum, Raya Habeeb Abdulimam Jan 2026

Prevalence Of Depression Among Doctors In General Hospitals Of Basrah City Center During The Covid-19 Pandemic, Riham Sabri Saleh, Amaleed Kadhum, Raya Habeeb Abdulimam

Iraqi National Journal of Medicine

Background: Depression is the most common mental disorder in community settings and a major cause of disability worldwide. In 1999, it was the fourth most common cause of disability globally, and by 2020, it is projected to become the second most common cause. Doctors, as the primary workforce in hospitals, endure significant emotional and physical stress, which may have been exacerbated by the COVID-19 pandemic. Aim: This study aimed to estimate the prevalence of depression among doctors during the COVID-19 pandemic and its risk factors. Methods: This descriptive cross-sectional study was conducted from February 1 to June 1, 2021. The …


Clinicopathological Features Of Colorectal Cancer In Young Patients In Comparison With Older Patients, Bahaa Al-Neama, Wasam Al-Asadi Jan 2026

Clinicopathological Features Of Colorectal Cancer In Young Patients In Comparison With Older Patients, Bahaa Al-Neama, Wasam Al-Asadi

Iraqi National Journal of Medicine

Background:  Colorectal cancer (CRC) has traditionally been considered a disease of older adults; however, recent evidence shows an increasing incidence among younger patients. Understanding the differences in clinicopathological features between young and older individuals is essential for improving early diagnosis, treatment strategies, and outcomes. Aim: The primary objective of this study is to compare the demographic profiles and clinicopathological characteristics of younger patients (aged <40 years) with those of older patients (aged ≥40 years) diagnosed with colorectal cancer. Methods: Eighty-five consecutive patients admitted to our hospital were prospectively followed for their entire hospital stay or up to 7 days, whichever came first. Each patient's blood glucose measurement was recorded according to ward protocol. Indices included total blood glucose per ward, per patient-day, or patient stay, and percentage blood glucose levels per predefined cut points to assess the incidence of hypo-, eu-, and hyperglycemia. The trial registration number at Clinicaltrials.org is NCT04800861. Results: Total data consisted of 645 blood glucose tests from 85 patients and 284 patient-day results, with an average of 2.27 tests per patient-day and 7.59 measurements per patient stay. The percentage of blood glucose in the range (80–180 mg/dL) varied by model, with patient-day showing the highest results at 48.24%, while the percentage of patients with hypoglycemia (blood glucose <60 mg/dL) was highest per patient stay at 1.18%. Conclusions: Younger colorectal cancer patients in this study presented more frequently with rectal tumors, poor differentiation, and advanced disease stages. Despite similar symptom profiles, delayed diagnosis may contribute to worse pathological features. These findings support the need for greater awareness and consideration of earlier screening in younger populations.


4-H Presents Multimedia Pilot 2026, Alison Coleman Jan 2026

4-H Presents Multimedia Pilot 2026, Alison Coleman

UNH Cooperative Extension

No abstract provided.


Aberrant Cd25 And Increased Cd123 Expression Are Common In Acute Myeloid Leukemia With Kmt2a Partial Tandem Duplication And Are Associated With Flt3 Internal Tandem Duplication, Qing Wei, Guilin Tang, Shaoying Li, Sa A Wang, Pei Lin, Wei Wang, Sanam Loghavi, Wei J Wang, L Jeffrey Medeiros, Jie Xu Jan 2026

Aberrant Cd25 And Increased Cd123 Expression Are Common In Acute Myeloid Leukemia With Kmt2a Partial Tandem Duplication And Are Associated With Flt3 Internal Tandem Duplication, Qing Wei, Guilin Tang, Shaoying Li, Sa A Wang, Pei Lin, Wei Wang, Sanam Loghavi, Wei J Wang, L Jeffrey Medeiros, Jie Xu

Faculty, Staff and Student Publications

Background: KMT2A partial tandem duplication (PTD) occurs in approximately 5-10% of acute myeloid leukemia (AML) cases and is associated with poor prognosis. While its cytogenetic and molecular features are well described, the immunophenotypic characteristics of AML with KMT2A-PTD remain incompletely defined.

Methods: We identified 47 cases of AML with KMT2A-PTD by optical genome mapping. All cases underwent flow cytometric immunophenotypic analysis and next-generation sequencing using an 81-gene panel.

Results: The cohort included 32 men and 15 women with a median age of 67 years (range, 19-87). Thirty-eight cases were de novo AML, and nine were secondary to myelodysplastic …


Role Of The Etv5/P38 Signaling Axis In Aggressive Thyroid Cancer Cells, Jerry H Houl, Rozita Bagheri-Yarmand, Muthusamy Kunnimalaiyaan, Paola Miranda Mendez, Joseph L Kidd, Ali Dadbin, Andrea Ruiz-Jurado, Parag A Parekh, Ying C Henderson, Nikhil S Chari, Aatish Thennavan, Reid T Powell, Clifford C Stephan, Xiao Zhao, Anastasios Maniakas, Roza Nurieva, Naifa L Busaidy, Maria E Cabanillas, Ramona Dadu, Mark Zafereo, Jennifer R Wang, Stephen Y Lai, Marie-Claude Hofmann Jan 2026

Role Of The Etv5/P38 Signaling Axis In Aggressive Thyroid Cancer Cells, Jerry H Houl, Rozita Bagheri-Yarmand, Muthusamy Kunnimalaiyaan, Paola Miranda Mendez, Joseph L Kidd, Ali Dadbin, Andrea Ruiz-Jurado, Parag A Parekh, Ying C Henderson, Nikhil S Chari, Aatish Thennavan, Reid T Powell, Clifford C Stephan, Xiao Zhao, Anastasios Maniakas, Roza Nurieva, Naifa L Busaidy, Maria E Cabanillas, Ramona Dadu, Mark Zafereo, Jennifer R Wang, Stephen Y Lai, Marie-Claude Hofmann

Faculty, Staff and Student Publications

Patients with poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) face a much poorer prognosis than those with differentiated thyroid cancers. Around 25% of PDTCs and 35% of ATCs carry the BRAFV600E mutation, which constitutively activates the MAPK pathway, a key driver of cell growth. Although combining BRAF and MEK inhibitors can shrink tumors, resistance often develops. The exact cause of this resistance remains unclear. We previously found that in PDTC and ATC cells, the BRAFV600E mutation is strongly linked to the expression of ETV5, a transcription factor downstream of the MAPK pathway. In the current study, we …


Do Monetary Policy Shocks Affect Co2 Emissions? Evidence From Brazil, Luccas Assis Attílio, João Ricardo Faria, Andre V. Mollick Jan 2026

Do Monetary Policy Shocks Affect Co2 Emissions? Evidence From Brazil, Luccas Assis Attílio, João Ricardo Faria, Andre V. Mollick

School of Economics and Finance Faculty Publications

This paper examines whether monetary policy shocks affect CO2 emissions over time in Brazil. We show that CO2 emissions decline persistently following contractionary monetary policy shocks. The relationship between monetary policy and CO2 emissions in Brazil is assessed through two channels: trade openness and exchange rates. The theoretical model illustrates how monetary policy affects the domestic economy through the real exchange rate. An application of a Global VAR (GVAR) to the Brazilian economy from 1996 to 2018 investigates the effects of monetary policy in Brazil (or in the U.S.) on real GDP and, subsequently, on CO2 emissions. A contractionary monetary …


Leadless Versus Transvenous Dual-Chamber Pacemakers: Real-World Evidence From Aveir Dr Coverage With Evidence Development Study., Monica Lo, Anish K Amin, Marcin Kowalski, Anne Kroman, Dilip Mathew, Valay Parikh, Stanislav Weiner, Jennifer M Joseph, Leonard Ganz, Mohammed Mortada Jan 2026

Leadless Versus Transvenous Dual-Chamber Pacemakers: Real-World Evidence From Aveir Dr Coverage With Evidence Development Study., Monica Lo, Anish K Amin, Marcin Kowalski, Anne Kroman, Dilip Mathew, Valay Parikh, Stanislav Weiner, Jennifer M Joseph, Leonard Ganz, Mohammed Mortada

Heart and Vascular Articles

BACKGROUND: AVEIR DR, an industry-first dual-chamber leadless pacemaker (LP), provides continuous atrioventricular synchrony through implant-to-implant (i2i) communication between atrial and ventricular LP devices. It is important to evaluate the early real-world comparative safety of AVEIR DR LP.

OBJECTIVE: To compare complications and mortality between AVEIR DR LP and dual-chamber transvenous pacemakers (TP).

METHODS: De novo LP and TP patients were identified in Medicare Fee-for-Service claims (October 2023 and December 2024). Outcomes were 30-day and 6-month complications, reinterventions, heart failure hospitalizations, and all-cause mortality. Comparisons were adjusted for demographics, comorbidities, and hospital encounter characteristics.

RESULTS: Compared to TP (N = 77 …


Differential Blood-Brain Barrier Permeability Driven By Asymmetric Hypoperfusion In A Vascular Dementia Model, Mengjun Dai, Kuizhi Qu, Ying Jiang, Song Gao, Yan-Ning Rui, Zhen Xu Jan 2026

Differential Blood-Brain Barrier Permeability Driven By Asymmetric Hypoperfusion In A Vascular Dementia Model, Mengjun Dai, Kuizhi Qu, Ying Jiang, Song Gao, Yan-Ning Rui, Zhen Xu

Faculty, Staff and Student Publications

Introduction: Blood-brain barrier (BBB) dysfunction has been associated with vascular dementia (VaD). However, the underlying mechanisms causing BBB dysfunction remain unclear, especially regarding cerebral hypoperfusion. This study aimed to investigate the effects of asymmetric hypoperfusion on BBB permeability using a mouse model of VaD.

Methods: Asymmetric bilateral common carotid artery stenosis (ACAS) was induced using ligature rings. BBB integrity was assessed on 3 days post-surgery using Evans blue, IgG, and albumin extravasation. A modified tissue processing protocol optimized endogenous marker detection. Regional and sex-based differences in BBB permeability were analyzed.

Results: Increased BBB permeability was observed in both corpus callosum …


Advances In Targeting Her2 Across Cancer Subtypes: A Pan-Tumor Approach, Taiwo Adesoye, Ecaterina E Dumbrava, Kanwal P S Raghav, Aysegul A Sahin, Hui Chen, Sunyoung S Lee, Milind M Javle, Shubham Pant, Omar Alhalabi, Xiuning Le, Vicente Valero, Paula R Pohlmann, Funda Meric-Bernstam Jan 2026

Advances In Targeting Her2 Across Cancer Subtypes: A Pan-Tumor Approach, Taiwo Adesoye, Ecaterina E Dumbrava, Kanwal P S Raghav, Aysegul A Sahin, Hui Chen, Sunyoung S Lee, Milind M Javle, Shubham Pant, Omar Alhalabi, Xiuning Le, Vicente Valero, Paula R Pohlmann, Funda Meric-Bernstam

Faculty, Staff and Student Publications

Human epidermal growth factor receptor 2 (HER2) is an established therapeutic target in multiple solid tumors, particularly breast and gastric cancers. Significant advancements have been made in the development of HER2-targeted therapies, including monoclonal antibodies, tyrosine kinase inhibitors, antibody-drug conjugates (ADC), and novel bispecific antibodies. These agents have revolutionized the treatment landscape for HER2-positive metastatic cancers, resulting in improved progression-free and overall survival, and quality of life for patients. Beyond breast and gastric cancers, HER2 expression/amplification has been observed in other solid tumors, such as colorectal, lung, bladder, ovarian, and biliary tract cancers, offering new opportunities for personalized therapy in …


Ai Derivation And Exploration Of Antibiotic Class Spaces, Adam Bess, Sean Rowland, Chris Alvin, Supratik Mukhopadhyay Jan 2026

Ai Derivation And Exploration Of Antibiotic Class Spaces, Adam Bess, Sean Rowland, Chris Alvin, Supratik Mukhopadhyay

Open Access Fund Publications

Purpose The rapid evolution of antibiotic-resistant bacteria poses an urgent global health crisis. A key gap in current antibiotic discovery approaches is the absence of automated chemical synthesis methods designed to systematically generate and evaluate compounds within specific antibiotic classes. We address this gap through fragment-based computational experiments that systematically explore antibiotic chemical spaces.

Methods Our computational methodology consists of three steps: fragmentation of known compounds (eMolFrag), generating new molecular structures by recombining fragments (eSynth), and filtering of candidates based on desired properties (eFilter). eFilter combines structural analysis, pathway information, and protein targets …


The George-Anne Inkwell Edition, Georgia Southern University Jan 2026

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


Prevalence And Factors Associated With Regular Fast-Food Consumption Among The Adult Population In Qatar: Cross-Sectional Analysis From Qatar Biobank Cohort, Alaa Zuhair Massarweh, Lynne Alexandra Kennedy, Asayel Saleh, Aljazi Al-Thani, Ala Al Rajabi Jan 2026

Prevalence And Factors Associated With Regular Fast-Food Consumption Among The Adult Population In Qatar: Cross-Sectional Analysis From Qatar Biobank Cohort, Alaa Zuhair Massarweh, Lynne Alexandra Kennedy, Asayel Saleh, Aljazi Al-Thani, Ala Al Rajabi

All Works

Background The Eastern Mediterranean Region has undergone a rapid nutrition transition over the last three decades, with healthier traditional table diets displaced by energy-dense convenience foods. To the best of our knowledge, this is the first large cohort-based estimate of regular fast-food consumption (RFFC >= 1 time/week) and its correlates among the adult population in Qatar using Qatar Biobank, a volunteer prospective cohort of Qataris and long-term residents.Methods A cross-sectional study using a simple randomized sample of 2,000 adult participants from the Qatar Biobank (QBB) longitudinal cohort. Dietary intake was assessed using a validated food-frequency questionnaire. RFFC was modeled as …


Onset And Exacerbation Of Obsessive-Compulsive Disorder In The Perinatal Period, Jack Samuels, Mary Kimmel, Janice Krasnow, Rashelle Musci, Paul S Nestadt, Lauren M Osborne, Eric A Storch, Jonathan S Abramowitz, Gerald Nestadt Jan 2026

Onset And Exacerbation Of Obsessive-Compulsive Disorder In The Perinatal Period, Jack Samuels, Mary Kimmel, Janice Krasnow, Rashelle Musci, Paul S Nestadt, Lauren M Osborne, Eric A Storch, Jonathan S Abramowitz, Gerald Nestadt

Faculty, Staff and Students Publications

Purpose: Obsessive-compulsive disorder (OCD) can emerge during pregnancy and the postpartum and may adversely affect mother and newborn. However, little is known about potential risk factors for the onset of OCD in the perinatal period. Therefore, we investigated the onset of diagnosed DSM-5 OCD in women followed from the second trimester of pregnancy to 6-months postpartum.

Methods: We followed 256 women from the 20-24th week of pregnancy to 6-month postpartum. Participants had psychiatric diagnostic interviews at baseline and 6-month postpartum and completed self-report instruments. We compared women with and without incident OCD on sociodemographic characteristics and clinical features.

Results: Of …


Performance Forum - January 16, 2026 (Special Event), Calida Jones Jan 2026

Performance Forum - January 16, 2026 (Special Event), Calida Jones

Performance Forum

No abstract provided.