Digital Commons Network^™

Psychosocial Outcomes In Adults With Cleft Lip And Palate: Exploring The Relationship Between Cleft Severity, Mental Health, And Treatment Satisfaction, Haley Hannabass

ETDs from 2020-2029

Introduction:This study aimed to examine psychosocial outcomes in adults with cleft lip and palate (CL/P), focusing on how cleft severity (unilateral versus bilateral) influences depression, anxiety, social functioning, oral health–related quality of life, and satisfaction with treatment outcomes. Individuals born with clefts often continue to face psychosocial challenges even after surgical repair, and limited research has compared how these outcomes differ by cleft type in adulthood. Materials and Methods:A cross-sectional design was used, including 24 adults aged 18 years and older who had undergone cleft repair and were finished or in active orthodontic treatment at UAB. Participants completed an online …

Handling Missing Data In Copd Research, Chia-Ying Chiu

ETDs from 2020-2029

Chronic Obstructive Pulmonary Disease (COPD) remains a major global health concern and one of the leading causes of death in the United States, affecting approximately 4.6% of adults and reaching a prevalence of 9.4% in Alabama according to 2024 National Health Interview Survey. The disease imposes a substantial burden on quality of life and healthcare costs and contributes to increased disability-adjusted life years and years of life lost, as highlighted by the 2022 Lancet Commission report. Despite its im-pact, COPD is frequently diagnosed only after irreversible lung damage has occurred, largely due to under-recognized symptoms and limited diagnostic tools. Early …

Development Of Salinomycin Analogs As Potential Anti-Cancer Agents, Pavan Goud Juluri

Theses and Dissertations

Salinomycin, a poly-ionophore antibiotic originally isolated from Streptomyces albus, exhibits antimicrobial activity against Gram-positive bacteria. Over the years Salinomycin has been studied in the effects it has on cancer, specifically cancer stem cells. Poly(ADP-ribose) polymerase (PARP) is an enzyme involved in DNA repair. Inhibiting PARP has been explored as a strategy in cancer treatment, particularly in cancers with defective DNA repair mechanisms, such as those with BRCA mutations. The benzo-thiazoles, and -imidazoles are identified as inhibitor scaffolds, which compete with nicotinamide in the binding pocket of human poly- and mono-ADP-ribosylating enzymes. Benzothiazole, and benzimidazole based compounds particularly with modification at …

Assessing Urban Flooding And Vegetation Impact In Dubai Creek Following The April 2024 Extreme Rainfall, Dana Alhammadi, Xin Hong

All Works

During April 2024, the United Arab Emirates experienced an unusual phenomenon of an intense rainfall episode between April 14 and 18 that resulted in massive flooding in urban environments, particularly low-lying areas such as Dubai Creek. As a tidal waterway with dense urban development and environmentally sensitive zones surrounding it, Dubai Creek is an ideal site for assessing environmental changes caused by to floods. The study employed pre-flood (14 April) and post-flood (18 April) high-resolution PlanetScope satellite images, in combination with QGIS analysis, to evaluate vegetation health and surface water changes. Quantification of affected areas from flooding was achieved through …

In-Situ Eval: A Modular Framework For Custom And Real-Time Rag Benchmarking, Ritvik Garimella, Kaushik Roy, Chathurangi Shyalika, Amit Sheth

Publications

Retrieval-Augmented Generation (RAG) has become the standard approach for integrating domain knowledge into Large Language Models (LLMs). However, fair comparison of RAG pipelines remains difficult: data preparation is often ad hoc, subsampling methods are opaque, parameters vary across implementations, and evaluation is fragmented. We present In-Situ Eval, a unified and reproducible framework that operationalizes the full RAG pipeline with configurable subsampling strategies and both RAG-specific and generic evaluation metrics. The platform supports two execution modes: an offline Dataset mode for evaluating precomputed outputs, and a live Retrieval mode for benchmarking RAG variants with state-of-the-art LLMs. Users can flexibly select datasets, …

Through The Ages: Reflecting On 250 Years Of Ai Technology, Ethan Brue

Faculty Work Comprehensive List

"The only thing historians know for certain is that humans have been proven quite inept at being certain, particularly when it involves the future."

Posting about the longterm influence of artificial intelligence from In All Things, an online hub that offers insight into maintaining and faithful and orthodox Reformed Christian worldview while fearlessly engaging in every aspect of contemporary life – until all is made new.

Through the Ages

Apolipoprotein E4 And Its Later-Life Health Effects On The Multiple Sclerosis Population, Dean Zeldich, Chia Hsin Cheng, Yi Guan, Sriman Narain, Bang-Bon Koo

Department of Neurology Faculty Papers

BACKGROUND AND OBJECTIVES: Multiple sclerosis (MS) is a chronic autoimmune disease causing neuroinflammation and neurodegeneration. The apolipoprotein E4 (APOE4) allele, a major genetic risk factor for late-onset Alzheimer's Disease, accelerates cognitive decline and neuroinflammatory processes, including blood-brain-barrier disruption. This study explores the impact of APOE4 on later-life health in MS patients using biomarkers from the UK Biobank.

METHODS: MS patients were grouped by APOE4 carrier status: MS-E4 and MS-nonE4. Age- and sex-matched non-MS controls (control-E4, control-nonE4) were included for comparison. Analyses assessed retinal nerve fiber layer thickness (RNFL) from optical coherence tomography (OCT), blood biomarkers, cognitive performance, and brain magnetic …

Micromobility In Nyc: 2025, Mike Owen Benediktsson Phd, Xuemeng Li Phd

Publications and Research

This report offers a statistical snapshot of micromobility across the city over a three-week period in late 2025. Our team of trained researchers systematically observed over 1,700 micromobility vehicles at 155 separate intersections across the five boroughs of New York City. Our primary findings describe overall patterns in the demographics of micromobility and vehicle behavior at city intersections, and show how this behavior is shaped by variations in infrastructure as well as individual-level attributes.

Mapping Post-Rainfall Recovery In Arid Regions Using A Hierarchical U-Net, Xin Hong

All Works

The United Arab Emirates (UAE) experienced an extreme rainfall event between April 15 and 17, 2024, and that resulted in severe flooding in its coastal regions. Dubai was among the most affected regions. This study applies a hierarchical deep learning model on PlanetScope imagery to detect flood inundation, quantify flood extent by land cover, and examine short-term recovery dynamics. While earlier work detailed the methodological development of a hierarchical U-Net model (Hong et al., in press), here we emphasize its application for monitoring resilience trajectories in an arid urban environment. Results show that approximately 22 km² of land was …

Metaverse-Enabled Digital Twins For Business And Smart Cities: Toward A Human-Centered Framework For Digital Transformation, Rasem Qudaih, Nicholas Caldwell, Imen Ben Salem, A. Karthi

All Works

Digital Twin (DT) technologies are increasingly changing how businesses and cities model, assess, and enhance complex systems. Traditional DTs have served as static representations of tangible assets, providing monitoring and predictive functionalities. However, minimal stakeholder engagement and a focus on specific sectors have often limited their full potential. The rise of the metaverse, reinforced by Extended Reality (XR) technologies, presents a unique chance to evolve DTs into immersive, interactive, and human-centered platforms for collaborative decision-making. This integration allows stakeholders to visualize and engage with multidimensional data in real time, facilitating predictive analysis, scenario planning, and participatory governance. In business environments, …

Generative Ai Use And Self-Learning In Higher Education: The Role Of Learning Difficulties, Dana Saleh, Areej Elsayary

All Works

The rapid development of GenAI tools and their adoption in education have shown promising potential to personalize learning experiences. However, their effectiveness is influenced by factors such as familiarity, frequency of use, and the impact on self-learning. This study investigates the undergraduate students' familiarity with Generative AI (GenAI) tools, their frequency of use, and the perceived impact of GenAI on self-learning, with particular consideration of differences between students with and without learning difficulties. Prompt engineering is also included as a secondary aspect of students' GenAI experience. The research employed a quantitative survey design, utilizing validated scales to measure familiarity, usage …

Assessing Mangrove Ecosystem Health And Identifying Optimal Planting Regions Using Remote Sensing And Gis In The Uae, Imen Ben Salem, A. Karthi, Yousef Nazzal

All Works

Mangrove forests play a critical role in carbon sequestration, biodiversity preservation, and coastal resilience, making their conservation and restoration essential in climate change mitigation. This study uses traditional field evaluations and remote sensing and geoinformatics (GIS) methods to examine how mangrove ecosystems in the United Arab Emirates (UAE) have changed over time and space. We used Landsat satellite data from 2001 to 2024 and a set of vegetation indices, including SMRI, NDVI, GNDVI, EVI, and NDCI, to examine spatial patterns in biomass distribution, vegetation density, and overall ecosystem health. CO2 sequestration is a bit more climate-impact resilient. Even though the …

Mapping Urban Vegetation Changes Using Planetscope Imagery And Gis: A Case Study Of The 2024 Dubai Flood, Sumayya Almansoori, Xin Hong

All Works

In April 2024, unexpected heavy rainfall triggered one of the most severe flooding events in Dubai’s recent history, causing widespread concern for urban infrastructure and green spaces. This study evaluates the flood’s impact on urban vegetation in South Dubai using high-resolution PlanetScope satellite imagery and the Normalized Difference Vegetation Index (NDVI). Vegetation conditions before and after the flood (April 14 and April 18–19, 2024) were quantified and compared using NDVI analysis within QGIS to assess changes in vegetation health and coverage. Results indicate significant declines in vegetation health in areas dominated by intensive turf management, such as Damac Hills and …

Modulation Of The Cgas-Sting Inflammation Pathway In Mouse Models Of Accelerated And Slowed Aging, Benjamin David Heckman

ETDs from 2020-2029

Chronic sterile inflammation (inflammaging) is a core pillar of aging, and the cGAS-STING innate immune pathway has emerged as a key driver of this process. However, how this pathway intersects with systemic endocrine signaling remains poorly understood. Here, we investigated the intersection of endocrine signaling and cGAS-STING activation using two complementary mouse models with opposing lifespan phenotypes: a short-lived, liver-specific glucagon receptor knockout (LKO) mouse and a long-lived growth hormone-releasing hormone knockout (GHRH-KO) mouse. We demonstrate that despite presenting with a metabolically healthy phenotype, female LKO mice exhibited a significantly reduced lifespan. We link this premature mortality to a sex …

Posterior Cerebellar Lobe Deviations And Social Cognition In Individuals With Psychosis And Their Unaffected Relatives, Andreea Maria Stanica

ETDs from 2020-2029

Social cognition deficits observed in psychotic disorders contribute to functional impairments. The cerebellum has been identified as a critical brain region involved in social cognitive processes, but the relationship between cerebellar structural deviations and social cognition in individuals with psychosis (probands) and their unaffected relatives remains unclear. Using normative modeling, this study examined cerebellar volume deviations in probands and their unaffected first-degree relatives and investigated associations with social cognitive and motor performance. Probands exhibited significant theory of mind deficits compared to relatives. Probands showed negative deviations in anterior cerebellar lobe relative to the norm, whereas relatives did not. Deviations in …

The Effectiveness Of A Web-Based, Edutainment Intervention On Hiv-Related Stigma, Hiv Knowledge, And Condom Use Self-Efficacy Among Black/African American Emerging Adults, Shirlacia Gray

ETDs from 2020-2029

The Effectiveness of a Web-Based, Edutainment Intervention on HIV-Related Stigma, HIV Knowledge, and Condom Use Self-Efficacy among Black/African American Emerging Adults SHIRLACIA S. GRAY APPLIED DEVELOPMENTAL PSYCHOLOGY ABSTRACT Background: Edutainment interventions were developed to increase knowledge, to influence people’s attitudes and behaviors toward sexual, social and public health issues, and to promote behavior change. This current study implemented an edutainment intervention to examine its effectiveness on increasing HIV knowledge, reducing HIV-related stigma, and increasing condom use self-efficacy among Black/African American Emerging Adults in Birmingham, AL. Methods: This current study used longitudinal data from the City Health-II intervention for secondary data …

Exploring Criminality Through A Developmental Lens: Contextual Effects From Childhood To Emerging Adulthood, Abigail Jeanette Anderson

ETDs from 2020-2029

Adolescent delinquency is a key predictor of later criminal behaviors and is associated with negative outcomes across education, employment, and health. Despite extensive research, gaps remain regarding the interplay of individual- and context-level factors in the development of delinquency, as well as the reliance on cross-sectional or retrospective designs. Guided by a social-ecological framework, the present dissertation examines how family, school, and neighborhood contexts interact with individual behaviors to shape pathways toward delinquency and adult criminality across childhood, adolescence, and early adulthood. The first study investigated the cascading effects of paternal engagement, parental aggravation, and early child behavior problems in …

Clinical Decision Support Using Medical Imaging Artificial Intelligence, Yun-Chi Lin

ETDs from 2020-2029

Medical imaging plays a central role in modern clinical decision-making, yet its effective integration with artificial intelligence (AI) remains challenged by real-world clinical constraints. This dissertation investigates how medical imaging-based AI frameworks can be strategically designed to support clinical decision-making for two distinct but clinically critical scenarios: acute pandemic care and chronic neurodegenerative disease management. In acute pandemic settings, such as the COVID-19 crisis, healthcare systems face an urgent need for rapid risk stratification under conditions of data scarcity and operational stress including surges in patient volume and limited medical resources. This work explores strategies for developing deep learning models …

Does Market Penetration Of Medicare Advantage Plans Impact The Financial Performance Of Texas Critical Access Hospitals?, Charles Anthony Brocato

ETDs from 2020-2029

ABSTRACT This study investigated the impact of increasing market penetration of Medicare Advantage plans on the financial performance of Critical Access Hospitals (CAHs) in Texas, specifically focusing on days cash on hand (DCOH) and operating margin (OM). With over 20% of Americans relying on CAHs for healthcare, the financial viability of these hospitals is crucial for rural community health. The study analyzed longitudinal data from 72 CAHs in Texas between 2018 to 2023, a period marked by significant changes in the healthcare landscape due to the COVID-19 pandemic. Despite increased enrollment in Medicare Advantage plans rising from 26% to 40%, …

The Efficacy Of Computerized Visual Scanning Training Tools In Vision Rehabilitation Following Acquired Brain Injury, Lulwah Almulhim

ETDs from 2020-2029

Various neurological conditions, including acquired brain injuries, can cause visual scanning deficits, which disrupt the ability to gather and interpret visual information. Computerized training tools, such as light boards, are utilized to enhance functional vision and occupational performance. The Dynavision (D2) is a well-established visuomotor training tool primarily utilized to address visual field and visual scanning deficits. The Bioness Integrated Therapy System (BITS) is a touchscreen-based rehabilitation tool designed to assess and enhance vision, motor skills, cognition, and balance. To our knowledge, normative data for BITS visual scanning programs have not been established. We conducted a scoping review to identify …

Editorial: Advancing Musculoskeletal Health: Bridging Basic And Clinical Research On Biomechanical Properties Of Joints, Ligaments, Tendons, And Associated Structures, Xin Jin, Snehal S. Shetye, Mengcun Chen

Center for Translational Medicine Faculty Papers

No abstract provided.

Staff Education To Improve Nurses' Knowledge And Confidence In Suicide Risk Assessment, Sherica Mcbride

Walden Dissertations and Doctoral Studies

The purpose of this Doctor of Nursing Practice staff education project was to strengthen nurses’ knowledge and confidence in suicide risk assessments. Suicide remains a crucial patient safety issue, and nurses report uncertainty in early recognition and intervention; therefore, brief, practice-proximal training is essential. The practice-focused question that informed this project’s purpose was whether a short education module with pre- and post testing improves nurses’ knowledge and confidence in suicide risk assessment. Three nurses participated in a structured session covering risk factors, warning signs, standardized screening, and safety planning. I then used descriptive analysis to compare their pre- and posttest …

Predicting Perceived Immigrant Threat To National Identity Based On Christian Nationalism, White Racial Centrality, And Social Dominance Orientation, Anna Caroline Kinney

Walden Dissertations and Doctoral Studies

Immigrants remain frequent targets of anti-immigrant hate speech, often amplified by right-wing media. Demographic factors such as Christian nationalism (i.e., the desire to preserve Christian symbols, beliefs, and policies preserved as the established religion of the United States), White racial centrality (i.e., an automatic association between the self and the White ingroup), and social dominance orientation (i.e., support for group-based hierarchies and inequality) significantly shape perceptions of immigrants as a threat to national identity. Although prior research has examined these factors independently, their relative importance in predicting perceived immigrant threat remains limited. Informed by intergroup threat theory, this quantitative study …

Reflective Parenting, Psychological Needs, And Parental Interpretation Of Children’S Negative Emotions, Julia Pappas

Walden Dissertations and Doctoral Studies

Parents’ ability to understand and respond effectively to children’s negative emotions plays a critical role in children’s emotional development and regulation. However, it remains unclear whether parents interpret negative emotions as potential signals of underlying psychological needs. Based in the conceptual framework of parental reflective functioning and basic psychological needs theory, and grounded in interpretivist- constructivist paradigm, the purpose of this basic qualitative study was to examine how parents interpret children’s negative emotions and how their meaning-making processes relate to basic psychological needs. Semistructured interviews were conducted with parents of children between ages 3 and 9 years old (N = …

Strategies Leaders In Structured Alternative Academic Environments Use To Improve Resource Management, Operational Efficiency, And Program Sustainability, Sean D. Clark

Walden Dissertations and Doctoral Studies

Leaders of structured alternative academic environments often struggle to sustain operations because of limited resources, fragmented leadership, and high staff turnover. This business problem is important to leaders of structured alternative academic environments because ineffective resource management and operational inefficiencies threaten program sustainability and continuity of services for at-risk student populations. Grounded in transformational leadership theory, the purpose of this qualitative pragmatic inquiry was to explore the strategies leaders in structured alternative academic environments use to improve resource management, operational efficiency, and program sustainability. The participants were six leaders from structured alternative academic programs in southeastern New Mexico. Data were …

Leadership Strategies Used By Entrepreneurial Ecosystem Resource Providers To Support Entrepreneurial Success, Sarah Niehaus

Walden Dissertations and Doctoral Studies

Failure to collaborate effectively within entrepreneurial ecosystems remains a significant concern for leaders of entrepreneurial ecosystem organizations. Without clear, actionable collaboration strategies, these leaders may struggle to support entrepreneurial success and make informed decisions that enhance financial performance. Grounded in Mockler’s complex adaptive systems theory, the purpose of this qualitative pragmatic inquiry was to identify and explore effective strategies some leaders within entrepreneurial ecosystem organizations use to collaborate in a manner that supports entrepreneurial success. Participants included seven leaders of entrepreneurial ecosystem organizations located in the Midwest United States with successful experiences using such strategies. Data were collected from semistructured …

Spartan Daily, January 27, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 2

The Global Extent Of The Grassland Biome And Implications For The Terrestrial Carbon Sink, A S. Macdougall, B Vanzant, J Sulik, S Bagchi, D Naidu, T O. Muraina, E. Hersch-Green

Michigan Tech Publications

Land cover data are commonly used to model the terrestrial carbon (C) sink, yet these data have wide margins of error that significantly alter estimates of global C storage. Here we demonstrate this data vulnerability in grasslands, which are critical to C cycling but whose estimated distribution has varied by >50 million km (3.5-42% of the Earth's terrestrial surface). Comparing multiple high-resolution land cover products with expertly annotated grassland data from six continents, we show sources of mapping error and discuss C implications based on 2023 United Nations (UN) FAO estimates. Past misidentification arose from inconsistent definitions on grassland identity …

Unh Online Programs Rise In U.S. News Rankings, Jeremy Gasowski

UNH Today Archive

No abstract provided.

Optimizing Practice Facilitation: A Comprehensive Study On Implementation Fidelity And Its Determinants, Demetria Marie Hubbard

ETDs from 2020-2029

Intervention outcomes cannot be fully understood without examining how implementation strategies are delivered. While implementation fidelity to interventions is well recognized as a determinant of effectiveness, the fidelity of implementation strategies—the methods used to support intervention adoption—remains under-documented and under-assessed. Without this information, it is difficult to contextualize why interventions succeed or fail across diverse settings. This three-paper dissertation focuses on practice facilitation (PF), a widely used strategy in primary care quality improvement, as implemented in the Heart Health Improvement Project (HHIP) in Alabama. HHIP, led by the Alabama Cardiovascular Cooperative and funded by the Agency for Healthcare Research and …