Digital Commons Network^™

Biological Evaluation Of Novel 6,9-Disubstituted Purine Analogues In High-Grade Serous Ovarian Cancer Cell Lines, Duygu Altiparmak, Deren Demi̇rel Yavuz, Pinar Kul Karadeni̇zli̇, İrem Durmaz Şahi̇n, Meral Tunçbi̇lek

Turkish Journal of Biology

Background/aim: High-grade serous ovarian cancer (HGSOC) remains one of the most aggressive forms of ovarian malignancy and frequently shows resistance to conventional therapies. This study aimed to synthesize a novel series of purine analogues, 6-[(4-substituted benzyl amine)/(4-substituted aniline)]-9-cyclopentyl purines, and evaluate their anticancer efficacy against HGSOC cell lines.

Materials and methods: We assessed the biological effects of the synthesized purine analogues on the OVCAR3, OVSAHO, and KURAMOCHI HGSOC cell lines using the sulforhodamine B assay. To investigate the mechanism of action, we conducted flow cytometry and western blot analyses, focusing on DNA replication and apoptosis.

Results: Among the tested compounds, …

Crow's Nest, February 23, 2026, Crow's Nest Staff

Crow's Nest

The February 23, 2026 issue of Crow's Nest.

Optimizing Patient Adherence Through Improved Technology-Based Communication By Enhancing Staff Efficiency At An Opiate Treatment Program Clinic, Jennifer Parsons

Doctor of Nursing Practice Projects

High rates of missed appointments and unreliable follow-up remain a problem in outpatient opioid treatment clinics. This project improved the communication workflow at a methadone maintenance clinic by strengthening reminder systems and staff coordination. A needs assessment found several problems: appointment reminders were inconsistent, tracking was unreliable, and staff communication often relied on manual handoffs. The project was to test a technology-based workflow designed to improve staff communication and reduce missed appointments. The Technology Acceptance Model and Lewin’s Change Theory guided the change. The clinic implemented automated reminders, secure messaging, and clearer documentation to support daily communication. A pre-post evaluation …

P*Law Week 2026: Student-Led Expert Panels Focusing On Public Service Law, Benjamin N. Cardozo School Of Law

Cardozo Law News Archive

Cardozo School of Law's annual Public Law Advocacy Week (P*LAW), hosted by the Center for Public Service Law, featured student-led panels on disability rights, labor law, LGBTQ+ rights, immigration law, environmental law, and international accountability. The event brought together students, alumni, faculty, and practitioners to discuss pressing public interest issues and careers in public service law.

Mcsa Forum Minutes 02/23/2026, Morris Campus Student Association

Morris Campus Student Association

No abstract provided.

Digital Competence Of Primary School Teachers In Andalusia (Spain): A Multidimensional Analysis Based On Self-Perceptions, Francisco Ábalos-Aguilera, Luis M. Romero-Rodríguez, Bárbara Mercedes Castillo Abdul Hadi

Artículos científicos

This study analyzes the self-perception of digital teaching competence (DTC) among primary education teachers in Andalusia, using an instrument based on the European DigCompEdu framework. Data were collected through a self-administered online questionnaire applied to a sample of 416 primary education teachers working in Andalusia. The study employed a mixed-methods design, combining quantitative analyses (descriptive, correlational, and comparative) with qualitative analysis of open-ended responses. Employing a mixed-methods approach, the research assesses teachers’ competence levels and examines differences according to professional experience, school ownership, teaching specialization, and territorial distribution. Results indicate that most teachers perceive themselves at intermediate levels of digital …

Shifting Focus: Youth Sports And Mental Health, Tara Boer

Faculty Work Comprehensive List

"Ultimately, athletes should be encouraged to develop their identity holistically. They are athletes, but they are first and foremost children of the King."

Posting about protecting mental health while participating in sports from In All Things, an online hub that offers insight into maintaining and faithful and orthodox Reformed Christian worldview while fearlessly engaging in every aspect of contemporary life – until all is made new.

Shifting Focus

The Echo: February 23, 2026, Taylor University

2025-2026 (Volume 113)

No abstract provided.

Experienced Nurses: Improving Retention By Implementation Strategies Found In Research And Those Applied In Practice, Hemilla Raju Matta

Creating Healthy Work Environments (CHWE)

Background & Purpose: The lack of literature focused on retention of experienced nurses reflects the need for more research in this area to help develop retention strategies and decrease turnover. Literature notes nurses want a safe work place, collegial relationships, supportive leadership and organization, and professional development. The purpose of this quality improvement project was to evaluate the effectiveness of a 12-week educational intervention aimed at professional development.

Methods: The quality improvement project was implemented at a community teaching medical center with outpatient services, located on the east coast post IRB approval. A pre/post educational interventional design method …

Q&A With Filmmaker Antonio Tarrell On 'Cole: Bridge To Justice', Clara Turnage

University of Mississippi News

OXFORD, Miss. – Antonio Tarrell is a Mississippi filmmaker who recently co-directed "Cole: Bridge to Justice," a documentary on the life and legacy of University of Mississippi icon Donald Ray Cole.

Synergistic Effect Of Different Ions And Hexadecyltrimethylammonium Bromide On Wettability Alteration For Carbonate Rock, Rafal S. Abdullah, Hussein Q. Hussein, Rana R. Jali

Baghdad Science Journal

Naturally carbonate reservoirs have very low oil recovery efficiency owing to their wettability and tightness of matrix. However, adding surfactant to brine solution can enhance oil recovery by changing the wettability of the carbonate rock surface from oil-wet to water-wet. In the present study, the effects of different brines in the presence of surfactant hexadecyltrimethylammonium bromide (CTAB), on the wettability of carbonate rock were investigated through different characteristics such as surface tension interfacial tension and contact angle. The best concentration of CTAB was investigated at 500 ppm in brine (NaCl) reduced surface tension and interfacial tensions to 42 mN/m and …

The Impact Of Vascular Endothelial Growth Factor, Neutrophil Gelatinase-Associated Lipocalin, And Interleukin-38 Food And Air Allergy Patients Following The Pandemic Of Covid-19 In Iraq, Esraa Hameed Khamees, Zaizafoon N. Nasif

Baghdad Science Journal

Allergies are a common health issue where the immune system reacts to substances in the environment that are normally harmless. This study further investigates the effects of vascular endothelial growth factor (VEGF), neutrophil gelatinase-associated lipocalin (NGAL), interleukin-38 (IL-38), immunoglobulin E (IgE), and the neutrophil-lymphocyte ratio (NLR) in these individuals, offering insight into the probable processes behind allergic responses following the pandemic. The study comprised 120 non-vaccinated females with previous COVID-19 infection. Groups included controls and food and air (F&A) allergic patients, with 60 individuals matched for age and gender. Serum levels of IL-38, VEGF, IgE, and NGLA were assessed using …

Best Friends, Jim Hannon/Staff

Documents

Kicking off National Pet Week with Miss UNA 1985, Alyssa Ashley, and her dog.

Freshman Wins Miss Una Title, Timesdaily

Documents

Bridgette DeLon Smith wins crown.

Cissy Ashley Commended By Alabama Legislature, East Lauderdale News

Documents

Miss UNA 1985 commended by the Alabama Legislature for her outstanding accomplishments.

Kitchens Chosen Miss Una, Itawamba County Times

Documents

Sondra Patrice Kitchens chosen as Miss UNA 1989.

The Secret Garden: Staff Caring For Staff, Erin Quinlan, Jennifer Schlebusch

Creating Healthy Work Environments (CHWE)

Healthcare workers provide for others in thoughtful, therapeutic ways, which becomes problematic if their mental and emotional resources are depleted. When healthcare workers experience a self-care deficit, their well-being and patient care are compromised. Recent factors contributing to staff stress include the impact of COVID-19 and the Pediatric Behavioral Health Crisis. An identified need to improve staff well-being was visible. The purpose of this quality improvement project, using the Plan-Do-Study-Act methodology, was to develop and implement the Secret Garden to improve the health of the work environment. The Secret Garden is a staff-only respite space, operationalized and managed to support …

Addressing Faculty Gaps In The Psychiatric Mental Health Nurse Practitioner Program, Shea Brock

Doctor of Nursing Practice Projects

Graduate nursing programs increasingly rely on adjunct faculty to sustain enrollment growth; however, inconsistent onboarding processes may contribute to variability in faculty preparedness and job satisfaction. The purpose of this quality improvement project was to implement a standardized adjunct faculty education program and evaluate its impact on adjunct faculty knowledge and job satisfaction within an online Psychiatric–Mental Health Nurse Practitioner (PMHNP) program. A quantitative, quasi-experimental one-group pre–post design was utilized. Six adjunct faculty members (n = 6) completed a 10-item EXXAT Knowledge Survey and a 10-item Faculty Satisfaction Survey before and after participation in a structured one-hour education session focused …

Breast Cancer Mortality In Memphis: A Holistic Approach - Research Findings And Strategies For Improved Outcomes In Segregated Communities, The Benjamin L. Hooks Institute For Social Change

The Hooks Institute Policy Papers

The Benjamin L. Hooks Institute for Social Change (Hooks Institute) is pleased to present its tenth edition of the policy papers, which focuses on breast health outcomes for women living in racially segregated commu-nities. The research that informed the articles in this publication, as well as this volume of the policy papers itself, was funded by a 2022 grant from the National Institutes of Health (NIH). The grant was awarded to a team of researchers that included Shelley White-Means, PhD (Principal Investigator); Arash Shaban-Nejad, MSc, MPH, PhD and Minghui Li, MSc, PhD (Co-Investigators) at University of Tennessee Health Science Cen-ter …

Examining Crime Trajectories At Micro Geographic Locations Across Varied Urban Contexts In The U.S., Xiaoshuang Iris Luo

University Research

Objectives

There is a lack of research for the spatial distribution of crime at micro geographic units across a variety of places. To address the research gap, this study examines crime trajectories over the most recent decade across a wide range of cities in the U.S.

Methods

Using cities of different sizes, developmental stages, and employment levels as the three criteria, official crime data from 12 U.S. cities between 2010 and 2018 are analyzed to examine crime trajectories at the street segment level. Group-based trajectory models are used to determine the distinct longitudinal trajectory profiles of violent crime and property …

Improving Rural Health Through Nutrition Incentives: A Mixed Methods Evaluation Of The First Year Of The Appalachian Farmacy Program, Bethesda O'Connell, Harrison Ihrig, Andrea D Nutsugah, Ignacio Garcia, Michael Rice, Ashley Cavender

Journal of Social, Behavioral, and Health Sciences

Food insecurity remains a critical public health concern, particularly in rural, low-income communities. In 2023, 13.5% of United States households experienced food insecurity, with rates in Tennessee (15.6%) exceeding the national average. Produce prescription programs have emerged as a strategy to improve food access and promote healthier eating behaviors. This study presents an evaluation of Appalachian Farmacy, a produce prescription program in Northeast Tennessee designed to increase fruit and vegetable consumption among individuals receiving Medicaid, Medicare, or Supplemental Nutrition Assistance Program (SNAP) benefits. Program evaluation methods included semi-structured interviews for process evaluation and pre- and post-surveys for outcome evaluation. Interviews …

Tree Diversity Is Changing Across Tropical Andean And Amazonian Forests In Response To Global Change, B. Fadrique, F. Costa, F. Cuesta, G. Arellano, L. Cayuela, T. R. Baker, F. C. Draper, A. Esquivel-Muelbert, H. Ter Steege, M. Bauters, J. Aguirre-Gutiérrez, Z. Aguirre-Mendoza, M. N. Alexiades, E. Alvarez-Davila, E. Arets, E. Ayala, C. G.A. Aymard, F. Baccaro, S. Báez, C. Baraloto, R. I. Barbosa, P. Barbosa Camargo, J. Barlow, P. E. Barni, J. Barroso, M. Benchimol, A. C. Bennett, E. Berenguer, L. Blanc, D. Bonal

School of Geography, Earth and Environmental Sciences

Climate and atmospheric changes are impacting forest function and structure worldwide, but their effects on tropical forest diversity are unclear. Nowhere is the scientific challenge greater than in the Andes and the Amazon, which together include the world’s most diverse forests. Here, using 406 permanent plots spanning four decades of intact lowland and montane forest dynamics, we test for long-term change in species richness and assess the influence of climate and other variables. We show that, at a continental scale, species richness appears stable, but this masks substantial regional variation. Species richness increased in Northern Andean and Western Amazon plots, …

Short-Term Spark Or Long-Term Flame? Sustaining Academic Psychiatric Departments, Rohit Shankar, Richard Laugharne, Derek K. Tracy, Dinesh Bhugra

Peninsula Medical School

SummaryOver the past two decades, the number of academic psychiatrists in the UK has declined by more than a third, despite an expansion in medical schools and growth in most other medical academic specialties. Drawing on direct experience of establishing a new academic unit, we argue that the long-term sustainability of academic psychiatry departments is critical for service quality, innovation and talent development. This paper outlines the structural, cultural and strategic factors needed to create academic units that endure and flourish beyond individual careers, enabling better integration of research and clinical practice.

Isolated Bacillus Licheniformis Sp01 From Daqing Oilfield In Reducing Chromium(Iii) Crosslinked Polymer Residue And Enhancing Oil Recovery, Xiao Hui

Student Works (2020-2029)

After polymer gel formation, the residual partially hydrolyzed polyacrylamide (HPAM) and the crosslinker (Cr3+) caused plugging and decreased oil recovery. Microorganisms can degrade HPAM to address the issues, but Cr³⁺ inhibits the process and reduces oil recovery. This study explores the underexamined biodegradation of HPAM and improved oil recovery in the presence of Cr³⁺, offering new perspectives for microbial enhanced oil recovery (MEOR) after polymer gel formation. HPAM and crude oil were innovatively used as the sole nitrogen(N) and carbon(C) sources to isolate the best-growing strain from Daqing Oilfield produced water, identified as Bacillus licheniformis SP01. The oil displacement potential …

20260223: The Green Book, 1956-1971, Academic Affairs

Guides to University Archives

These items include materials from the office of Academic Affairs at Marshall University from 1956-1971. Items were received at an earlier date (likely the 1990s) but were not accessioned until 2026. Materials in this collection include The Greenbook or Green Book publication from 1956-1971.

Unh Research Could Lead To Stronger, Lighter Everyday Materials, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Preparation, Characterization, And Antimicrobial Evaluation Of A Cefepime Derivative With Divalent Transition Metals, Zahraa A. Jaber, Israa H. Ibraheem, Sahar S. Hassan

Baghdad Science Journal

The Schiff base ligand (L)- 1-((7-((Z), was recently synthesized 2–(2-((Z)–5,5-diethyl2-(methoxyimino)acetamido)-2-(methoxycarbonyl)-2,6-dioxotetrahydropyrimidin-4(1H)-ylideneamino) thiazol-4-yl8-oxo-5-thia , the next mineral ions, Ni²⁺, Cu²⁺, Zn²⁺, and Co²⁺, are permitted to react with 1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-methylpyrrolidinium, leading to the formation of new metal complexes with distinct geometric shapes. By detecting the shifting in the azomethines band and the appearance of M-N and M-O bands, FT-IR confirmed the occurrence of coordination through N of azobenzene and two O atoms of beta lactam and ester, indicating the development of Schiff base complexes as well as the original Schiff base. Additionally, we can use …

Determination Of Mebeverine – Hcl Using 3, 5–Dinitrosalicylic Acid And Multiple Continuous Flow Cell That Works As A Solo Flow Cell With 4s×3 – 3d Analyzer, Elham N. Mezaal, Nagam S. Turkey

Baghdad Science Journal

A new method, simple and sensitive was utilized in determining mebeverine – HCl (MB-HCl) (3, 4-Dimethoxy benzoic acid ethyl 2, 4 methoxy4-phenyl-1-methyl ethyl amino-butyl ester) in pure and pharmaceutical formulations via utilization this multiple continuous flow cell. The method is dependent on genesis for complex of ion pair(4-((3, 4-dimethoxybenzoyl) oxy)-N-ethyl-N-(1-(4-methoxyphenyl) propan-2-yl) butan-1-aminium-2-hydroxy-3,5-dinitrobenzoate) among mebeverine–HCl (MB-HCl) and 3,5-Dinitrosalicylic acid (3,5-DNSA) in ammonium acetate middle to configure a whiteish yellow precipitate compound via utilizing multiple continuous flow cell that works as a solo flow cell with 4S×3 – 3D analyzer. Optimum parameters were studied to raise the sensitivity for improving the method. …

Colleges Face A Choice: Try To Shape Ai’S Impact On Learning, Or Be Redefined By It, Vicki Baker, Linda M. Boland

Biology Faculty Publications

What happens to a college education when a chatbot can draft an essay, summarize a reading and generate computer code in seconds? The arrival of artificial intelligence in college classrooms has been swift and, for many schools, disorienting.

As professors of economics and business management and biology at liberal arts colleges, we are confronting a question that now cuts across all colleges and universities: What is the purpose of a college education, as AI is rapidly reshaping how students think, learn and prepare for careers?

Leveraging Best Practice Initiatives To Develop An Innovative And Proactive Approach To Stress Management, Shannon Cronin Patel, John Hunt, Mary Law

Creating Healthy Work Environments (CHWE)

Background: A 2023 Premiere Inc. survey reported that greater than 40% of US healthcare professionals have experienced at least one episode of workplace violence during the past two years. Confounding issues position healthcare professionals at increased risk for experiencing daily stress inducing situations including but not limited to: staffing related deficiencies, increased incidences of workplace violence, and increased risk for secondary victim incidents that perpetuate wounded healers. Despite increases in stress inducing situations, current stress mitigating interventions remain reactive, antiquated, and fail to meet the emotional needs of healthcare professionals. Current stress and critical incident management models provide reactive support …