Digital Commons Network^™

Optimized Deep Learning Framework With H2o For Lung Cancer Prediction, Walaa Hassan Ibrahim, Mohamed S. Saraya, Sally M. Elghamrawy, Ali I. Eldesouky

Mansoura Engineering Journal

The automatic diagnosis of lung cancer using chest X-ray (CXR) images has significantly advanced with progress in computing, machine learning, and deep learning. However, detecting lesions and nodules remains challenging due to CXR limitations. Early lung cancer detection is critical for successful treatment, but current AI algorithms often rely on large annotated datasets, which are not always available. To address this, a novel multi-classification deep learning framework is proposed that combines CXR and CT images. This approach leverages the detailed feature detection capabilities of CT scans alongside the complementary views from CXRs, improving early-stage lung cancer detection and classification precision. …

Triphenylmethane-Derived Levelers For High-Speed Redistribution Layer Copper Electroplating Of Tailored Surface Morphologies, Zi-Hao Song, Wei-Bin Wang, Xiao-Hui Liu, Xiao-Min Han, Yi Zhou, Rui Huang, Yan-Xia Jiang, Zhe Li, Xiao-Wei Liu, Mei-Ling Xiao, Hong-Gang Liao, Wei-Lin Xu, Rong Sun

Journal of Electrochemistry

Redistribution Layer (RDL), composed of layered dielectrics and electroplated copper materials, is a basic structure to rearrange numerous I/O pads on the chip surface in wafer-level advanced packaging. As the key chemicals in electrolyte baths, electroplating additives have undergone continuous development to meet the industrial needs for high-speed and fine-line/fine-pitch applications. Meanwhile, the intricate relationships between additive chemical structures and electroplated copper properties are yet to be well understood. In this work, a pair of triphenylmethane-based dye molecules, i.e., gentian violet (GV) and methyl green (MG), was comparatively investigated as levelers for high-speed RDL copper electroplating. Compared to GV, significantly …

Aav Gene Therapy For Mps Iva With Induction Of Immune Tolerance Via Oral Administration Of Epitope Peptides Of N-Acetylgalactosamine-6-Sulfate Sulfatase, Sampurna Saikia, Yasuhiko Ago, Fnu Nidhi, Shaukat Khan, Zhengyu Ma, Shunji Tomatsu

Department of Pediatrics Faculty Papers

Mucopolysaccharidosis IVA (MPS IVA) is caused by the accumulation of undegraded glycosaminoglycans due to the deficiency of the N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme. MPS IVA manifests as progressive systemic skeletal dysplasia. Gene therapy (GT) is potentially a one-time treatment in which the enzyme is continuously produced, circulated, and delivered to target tissues. However, immune responses to gene products can diminish therapeutic efficacy. We hypothesized that oral delivery of tolerogenic peptides induces immune tolerance to human GALNS (hGALNS) in MPS IVA mice, enhancing therapeutic efficacy. Neonatal mice deficient in mouse GALNS (mGALNS) were treated orally with three T-cell/B-cell epitope peptides or hGALNS …

In Vitro Studies Of The Effects Of Antithrombotic Zn-Dipicolylamine-Harboring Liposomes (Dpals) On Serum Albumin And Human Umbilical Vein Endothelial Cells, Michelle Tanujaya, Gianna Cai, Jia Patel, Zana Moldavsky, Yumna Ejaz, Malia Mahazabin Ahmed, Sangsang Duong, Lawrence E. Goldfinger, Koon Y. Pak, Brian D. Gray, Parkson Lee-Gau Chong

Cardeza Foundation for Hematologic Research

Thrombosis remains a leading cause of cardiovascular morbidity and mortality. During thrombosis, activated platelets and endothelial cells expose phosphatidylserine (PS) on their outer membranes, creating a surface that accelerates clot formation. Current antithrombotic therapies, such as heparin and warfarin, carry significant bleeding risks, highlighting the need for safer alternatives. In response, we developed a PS-targeting liposomal formulation composed of Zn-dipicolylamine (DPA)-cyanine-3[22,22] and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (molar ratio 3:97). This DPA-harboring liposome (DPAL) binds selectively to PS-rich surfaces such as activated platelets and has demonstrated efficacy in reducing thrombosis in mouse models, with minimal bleeding. In the present study, we examined the interaction …

Cumulative Disadvantage: Ethnic Inequalities In Criminal Court Proceedings In England And Wales, Kitty Lymperopoulou

School of Law, Humanities and Social Sciences

Scholarship on ethnic disparities in the criminal justice system has predominantly focused on disparities at a single decision-making point, mainly at sentencing, while earlier decision points remain underexamined or are studied in isolation to sentencing decisions. Using linked Ministry of Justice Data First datasets from criminal courts in England and Wales, this study assesses ethnic disparities at multiple decision points—from pre-sentencing to sentencing. Findings from multilevel logistic regression models demonstrate ethnic disparities across decision points, evidencing more pronounced disparities at pre-sentencing stages. Black and mixed ethnicity defendants consistently experience more disadvantaged outcomes, being more likely to be detained prior to …

Factors Affecting The Adoption Of Artificial Intelligence-Driven Wearable Technology In The Malaysian Healthcare Sector: A Conceptual Framework, Syeda Hafsa Rizwan, Anusuyah Subbarao, Nasreen Khan, Farrukh Ahmed Khan, Shaikh Fazlur Rahman, Nimra Aziz, Syed Muntazir Azhar Shah

International Journal of Management, Finance and Accounting

This conceptual paper examines the adoption of Artificial Intelligence (AI)-driven wearable technology, including smartwatches, fitness trackers, wearable ECGs, glucose monitors, and pain management devices, in transforming healthcare in Malaysia. Despite the extreme potential to enhance patient care and healthcare monitoring, the adoption of AI-driven wearable technology remains limited due to several persistent barriers. The purpose of this study is to examine these challenges and propose a framework to improve the integration of AI-driven wearable technology in Malaysia’s healthcare system. Grounded in the Diffusion of Innovation (DOI) theory, this study examines how five key innovation attributes —relative advantage, compatibility, complexity, trialability, …

Drawing Inspiration From The Magic Of The Unconscious In The Surrealist School, In The Works Of Jamil Jamoudi And The Works Of Aminollah Rezaei: A Comparative Study, Bashar Noumi

Journal of Language, Literature, and Arts

This paper provides a comparative analysis of the embryonic Surrealism of two well-known figures of the era: Jamil Hamoudi, an Iraqi surrealist artist, and Aminullah Rezaei, an Iranian surrealist artist. The results found that Surrealism in Iraq associated itself with cultural identity and sacred symbolism, unveiling Hamoudi as the merger of geometry, calligraphy, and warm colours, towards reshaping the collective unconscious and reformulating Eastern spirituality in a modernist fashion. While Surrealism itself was an American import, Surrealism in Iran was contained within a frame of clinical satire, with Rezaei using hybrid bodies and anatomical distortions within realism and fantasy to …

Resepsi Masyarakat Terhadap Nasionalisme Dalam Film Merah Putih: One For All, Ahmad Zahran Razaq, Bunga Anggreani, Novi Maslakhatul, Sutrisno Gustiraja Alfarizi, Didin Widyartono

Journal of Language, Literature, and Arts

Film is an effective medium for conveying moral messages and national values to society. This study aims to analyze public perception of the nationalism-themed film Merah Putih: One for All through netizen comments on social media. The research employs a descriptive qualitative approach using content analysis. Data were collected from comments on YouTube, Instagram, TikTok, and X (Twitter) during the initial release period of the film. The analysis focuses on how audiences interpret values of nationalism, unity, and the relevance of the film’s message within contemporary social contexts. The findings reveal that public reception is ambivalent. Some audiences appreciate the …

Motif Parang Barong Sebagai Inspirasi Penciptaan Tote Bag Rajut Dengan Teknik Crochet, Farah Mawaddatur Rahmah, Ike Ratnawati

Journal of Language, Literature, and Arts

Motif Parang Barong merupakan salah satu warisan budaya Jawa yang sarat akan makna filosofis tentang keteguhan, kebijaksanaan, dan kepemimpinan. Dalam konteks kehidupan modern, nilai-nilai tersebut diangkat kembali melalui penciptaan karya kriya terapan berupa tote bag rajut dengan teknik crochet. Karya ini tidak hanya berfungsi sebagai upaya pelestarian budaya, tetapi juga sebagai bentuk dukungan terhadap pengurangan penggunaan plastik sekali pakai dengan menghadirkan alternatif tas yang ramah lingkungan, tahan lama, dan dapat digunakan berulang kali. Tujuan utama penciptaan ini adalah menghasilkan tote bag rajut bermotif Parang Barong yang mampu memadukan unsur tradisional dan modern dalam satu rancangan desain yang fungsional, estetis, dan …

Trust In Regulation In A Time Of Revolution, Cristie Ford

All Faculty Publications

In a moment when big-P Politics feel practically catastrophic, the suggestion that we should be focusing on regulation could seem foolish, or worse: it could seem like some kind of self-serving effort to pretend our work rearranging deck chairs continues to matter. Regulation can feel like the opposite of resistance, and resistance is on many peoples’ minds these days, particularly in the United States. And, the goal of this paper is to argue that failing to focus on regulation – and especially on trust in regulation, in this time of revolution – would be a terrible mistake. Regulation is at …

Physiological And Neurological Impact Of Biophilic Design In Architectural Design Studios: A Case Study Of King Salman International University, Islam Ashraf Mohamed, Alaa El-Eishy, Marwa A. Soliman

Mansoura Engineering Journal

Biophilic design integrates nature into architecture to enrich sensory and cognitive experiences, enhance psychological well-being, and improve performance. This study explores its physiological and neural effects in design studios at King Salman International University through an experimental methodology combining theoretical review and lab-based investigation. Tools included electrocardiography (ECG) for heart rate variability (HRV), eye-tracking for visual attention, and the Self-Assessment Manikin (SAM) for emotional evaluation. Nine participants viewed five digital architectural scenes with varying biophilic integration. Direct nature connections elicited greater visual attention, pleasure, and perceived control, indicating higher engagement and relaxation.  A scene lacking biophilic elements led to reduced …

Colorenal Fistula In A Patient With Recurrent Urinary Tract Infections And Urinary Urgency: A Case Report, Joey E. Maksoud, Lauren Peter, Elissa Zakharia, Brady Werth, Philippe Nabbout

Student Publications

Colorenal fistula is a rare condition resulting from chronic inflammation, malignancies, diverticulitis, or infection. This case examines a 68-year-old female with a history of urinary urgency, left back pain, and recurrent urinary tract infections. Anteroposterior non-contrast computed tomography scan showed a large stone in the renal pelvis and gas in the collecting system. Left ureteroscopy revealed multiple ureteral polyps. Retrograde pyelogram revealed contrast filling the left colon. Ureteral polyp biopsies were benign, and colonoscopy was negative for malignancy. This case describes the occurrence of a colorenal fistula in a patient with no history of surgery, malignancy, or diverticulitis.

Sectoral Shockwaves: Examining Bursa Malaysia's Sector Indices Amid The Covid-19 Pandemic, Alyssa April Dellow, Hafizah Bahaludin

International Journal of Management, Finance and Accounting

The Coronavirus disease 2019 (COVID-19) outbreak is becoming a widespread concern, as it is causing a decline in economies and negatively impacting stock markets worldwide. As the Malaysian government implements the Movement Control Order (MCO) to curb the spread of the deadly virus, the Malaysian stock market is rapidly impacted, becoming volatile and unpredictable throughout the pandemic phase. Thus, this study aims to analyse the structural correlation patterns of the Bursa Malaysia Sectoral Index Series using the threshold network approach. The data utilised in this study are the closing prices of all 13 sectoral indexes, spanning from January 1, 2019, …

Understanding The Happiness Journey Of International Students Through Maslow's Lens: A Qualitative Study Beyond Academics, Kyra Law Ley Sy

International Journal of Management, Finance and Accounting

This research investigates the factors contributing to happiness among international students at a Malaysian university through a qualitative, semi-structured questionnaire administered to 10 students (5 female and 5 male) from nine countries. Four key themes emerged, aligning with Maslow’s Hierarchy: 1) Personal Achievement and Academic Fulfillment- happiness derived from educational success and career progress; 2) Social Connection and Belonging- the importance of relationships and cultural integration; 3) Health and Environmental Comfort- adaptation to climate and living conditions; and 4) Internal Reflection and Emotional Regulation- the impact of mindset and coping mechanisms on overall happiness. The research demonstrates that international student …

Gamification Strategies And Customer Churn Reduction In Entrepreneurial Retail Firms: An Empirical Study Of Millennials, Si Chong En, Oo Yu Hock, Nor Azila Mohd Noor, Zheng Feei Ma, Khairul Nizam Mahmud

International Journal of Management, Finance and Accounting

This study investigates the impact of gamification strategies on customer churn reduction in entrepreneurial retail firms, focusing on Millennial consumers in Malaysia’s Klang Valley. Customer churn threatens profitability, particularly for emerging enterprises, and gamification has emerged as a potential tool to enhance customer engagement and retention. Drawing on the Self-Determination Theory, the study examines three gamified marketing interventions: membership programmes, contest rewards, and personalised discounts as direct predictors of churn reduction. A quantitative, cross-sectional research design was employed, using a structured questionnaire distributed to 180 Millennial consumers through purposive sampling. The data were analysed using Partial Least Squares Structural Equation …

Investigating Volatility Spillover Between The Energy Market And The Sectoral Stock Markets In Malaysia: Evidence From Vhar-Type Models, Mariam Mohamed Abdelwahab Mohamed Badawi, Sew Lai Ng, Ruzanna Ab Razak

International Journal of Management, Finance and Accounting

This study examines the realised volatility spillover effects between Malaysia's energy market and other sectoral indices on the Kuala Lumpur Stock Exchange from September 2018 to December 2024. To address the limitations of current volatility modelling approaches, this study employs the Vector Heterogeneous Autoregressive (VHAR) model combined with the Realised Range-Based Volatility (RRV) measure to capture heterogeneous market behaviours at daily, weekly, and monthly time horizons. High-frequency data from September 2018 to December 2024 (earlier data are unavailable for some sectors) were collected from the financial data provider Bloomberg. The findings reveal that the energy sector exhibits strong volatility persistence, …

Neutrosophic Finsler–Cohomological Framework For Engineering Systems Under Uncertainty, Mona Gharib, Ghulam Muhammad, Muhammad Idrees, Zeeshan Gul

Neutrosophic Systems with Applications

This paper introduces a novel mathematical framework that combines Neutrosophic Finsler Geometry with Neutrosophic Cohomology for evaluating the performance of Brushless Direct Current (BLDC) motors under uncertain and indeterminate operating conditions. Classical motor performance models typically assume precise measurements of torque, current, and efficiency; however, in real-world settings, these parameters are often affected by noise, incomplete information, and conflicting observations. By embedding motor operating states into a neutrosophic Finsler space, the proposed approach captures variations not only in magnitude but also in direction, uncertainty, and conflict of performance metrics. In addition, neutrosophic Cohomology is employed to characterize global invariants of …

An Uncertainty-Aware Entropy-Oreste Framework For Big Data Platform Selection In Complex Multi-Sector Environments, Ahmed M. Ali, Ibrahim Alrashdi, Karam M. Sallam

Neutrosophic Systems with Applications

The increasing reliance on Big Data platforms across various industries has necessitated the development of systematic decision-support frameworks to guide their evaluation and selection. Given the diversity of available platforms, each offering different capabilities, scalability, and computational efficiency, choosing the optimal solution remains a complex challenge. This research proposes a novel analytical framework that integrates Spherical Fuzzy Sets (SFS) with the Entropy and ORESTE methods to address uncertainty and enhance the accuracy and robustness of Big Data platform evaluation. This hybrid integration, not previously applied to Big Data platform selection, enables objective criteria weighting through the Entropy method and comprehensive …

Rate And Characteristics Of Frequent Attenders At Primary Healthcare Centres In Muscat Governorate, Oman: A Cross-Sectional Study, Manar Al Sanaa Ali Alzeedi, Najlaa Jaafar Mohammed, Fatma Al Hadhrami, Hadya Al Lawati, Muna Aal Talib, Rahma Al Riyami, Rahma Al Shuhaimi, Wiam Al Tuqi

Sultan Qaboos University Medical Journal

Objectives: Frequent attenders (FAs) are patients who use primary healthcare centre (PHC) services at disproportionately high rates which puts a strain on health systems and affects the quality of care. This study aimed to determine the prevalence of FAs in PHCs in Muscat Governorate, Oman, and to identify their demographic, socioeconomic and clinical characteristics. Methods: This cross-sectional study was conducted across 10 randomly selected PHCs in Muscat from January to December 2024. Data were collected retrospectively from electronic medical records for 2023. FAs were defined as individuals with 10 or more visits per year. Descriptive statistics and multivariate Poisson regression …

Single-Valued, Double-Valued, Triple-Valued, Quadruple-Valued, And Quintuple-Valued Neutrosophic Graph, Takaaki Fujita, Arif Mehmood, Arkan A. Ghaib

Neutrosophic Systems with Applications

Concepts such as fuzzy sets, neutrosophic sets, rough sets, and plithogenic sets have been extensively studied as formal tools for modeling uncertainty, and they have found broad applications across many disciplines. A Double-Valued Neutrosophic Set (DVNS) extends the classical neutrosophic framework by splitting indeterminacy into two distinct components: one leaning toward truth and the other leaning toward falsity. In recent years, further refinements—namely Triple-Valued, Quadruple-Valued, and Quintuple-Valued Neutrosophic Sets—have also been introduced and investigated. These uncertainty models have naturally been lifted to graph-theoretic settings, where vertices and edges represent entities and relationships under ambiguity. Although fuzzy graphs and neutrosophic graphs …

Evaluating Domains' Trustworthiness Based On Uncertainty-Driven Methodologies In The Era Of Sixth Generation, Zekra Sakr, Mona Mohamed

Neutrosophic Systems with Applications

The onset of today's innovations pledges to have a beneficial influence on contemporary civilization in an era of intelligent revolutions, setting a precedent for unrivaled efficiency, creativity, and connectedness. The integration between these technologies contributes to the mutual benefit of each one, wherein this relation is a so-called ``reciprocal partnership''. For instance, the sixth generation (6G) wireless networks permit blockchain nodes to coordinate huge volumes of transaction data in real-time. On the other hand, blockchain is considered a secure valve because spectrum sharing can be automated with blockchain and smart contracts. Accordingly, analyzing and evaluating the contribution of these technologies …

Desegregating The Community Of Inquiry In Philosophy For/With Children, Maughn Rollins Gregory, Darren Chetty

Department of Educational Foundations Scholarship and Creative Works

This dialogical article examines persistent challenges in engaging racism, colonialism, and white supremacy within the theory and practice of Philosophy for/with Children (P4/wC). Framed as a mutual interview between two long-standing colleagues, the dialogue revisits formative encounters in the P4/wC community and situates them within broader intellectual traditions, including American pragmatism, deliberative democracy, and Africana philosophy. Drawing on personal experience, archival material, and critical scholarship, the authors interrogate the metaphilosophical assumptions underpinning the “community of inquiry,” particularly its commitments to reasonableness, consensus, and democratic dialogue. Concepts such as the “gated community of inquiry,” white ignorance, nonideal theory, and insurrectionist ethics …

Exploring The Optimal Age For Total Knee Arthroplasty To Minimize Risk Of Adverse Outcomes: Machine Learning Analysis Of A Statewide Cohort, Chloe Heiting, Yiyuan Wu, Susan M. Goodman, Peter Sculco, Fei Wang, Said A. Ibrahim, Peter Cram, Rich Caruana, Bella Mehta

Department of Medicine Faculty Papers

BACKGROUND: Rates of total knee arthroplasty (TKA) in the United States have risen in patients of a wide age range. Although rates of postoperative TKA complications have decreased, they remain a significant concern. In this study, we aim to determine how the risk of adverse TKA outcomes changes dynamically with age and explore the optimal ages with the lowest risk for adverse outcomes.

METHODS: This retrospective cohort study included patients who underwent elective primary TKA from 2012 to 2018 in the Pennsylvania Health Care Cost Containment Council Database. We trained (70% train:30% test) an explainable boosting machine (EBM), a modern …

Pemahaman Warna Pada Siswa Kelas 1–2 Sd Melalui Kegiatan Mewarnai Sebagai Stimulus Kreativitas Di Lembaga Kursus, Milarosa Elisia, Sumarwahyudi Sumarwahyudi

Journal of Language, Literature, and Arts

This study is based on variations in color understanding among first- and second-grade elementary students during coloring activities at LKP Windyas Club Malang. These differences influence the development of children’s visual creativity. Drawing on Johannes Itten’s color theory and J. P. Guilford’s concept of creativity, this research aims to examine the relationship between color understanding and creative ability in non-formal art learning. A descriptive qualitative approach was employed, with data collected through observation, interviews, and documentation. Data analysis followed the Miles and Huberman model, including data reduction, data display, and conclusion drawing, supported by triangulation to ensure validity. The findings …

Kunci Popularitas Streamer Youtube, Humor Sopan Santun Ala Windah Basudara Atau Bar-Bar Ala Deankt, Moh. Faidatul Nur Imansyah, Muhammad Evan Dibayana, Anggoro Saputra

Journal of Language, Literature, and Arts

This study examines the popularity of two Indonesian YouTube streamers with contrasting personas: Windah Basudara, known for his polite communication style, and DeanKT, known for his unfiltered and aggressive style. Grounded in the concepts of personal branding and digital persona, this research aims to analyze how differing language styles shape online identity, influence audience perception, and impact commercial aspects such as brand safety. This study employs a qualitative descriptive approach using a case study strategy and content observation, supported by quantitative data collected through an online questionnaire with 57 respondents selected purposively. The findings reveal that humor and entertainment value …

Aggregation Of Gene Regulatory Information And Knowledge On Fair Principles Enables Discovery Of Pathogenic Gene Regulatory Variants, Keyang Yu, Haoquan Zhao, Andrea S Wilderman, Tierra R Farris, Jessie E Arce, David Chen, Andrew R Jackson, Yiran Guo, Qi Li, Bosko Jevtic, Dubravka Jevtic, Vuk Milinovic, Yuankun Zhu, Jeremy Costanza, Eric D Wenger, Christopher Nemarich, Lisa Anderson, Aleksandar Mihajlović, Kristin Ardlie, Shaine A Morris, Matthew E Roth, Deanne M Taylor, Adam C Resnick, Lilei Zhang, Aleksandar Milosavljevic

Faculty, Staff and Students Publications

Motivation: Methods for sharing gene regulatory information and knowledge on FAIR principles, particularly in the context of tissue-specific gene regulation, remain poorly defined and implemented, hampering discovery and clinical genetic diagnosis.

Results: We specified FAIR principles for tissue-specific gene regulatory information and knowledge; implemented them by developing a registry of regulatory elements and aggregating FAIR gene regulatory information from several major sources; developed computational tools that utilize these FAIR resources; and demonstrated their utility by associating gene regulatory variants with major subtypes of congenital heart disease.

Perkembangan Dan Ruang Lingkup Sosiologi Hukum, Mulyana W. Kusumah

Jurnal Hukum & Pembangunan

Abstract

The Labor Of Reading: A Personal And Pedagogical Exploration, Alisha Goldblatt

Wellspring: A Practitioner-Oriented Journal of Literacy and Language Education

While teachers bemoan the decrease in students’ ability to sustain interest in reading, and phones dominate over plain text, I have been wrestling with two questions that predate the current ubiquity of screentime: Why are some people more capable of reading fluently and with passion than others? Why can’t every person easily “lose” themselves in a text? As an English teacher and avid reader, I investigate the mechanisms of the act of reading (mainly fiction and creative nonfiction), the well-intentioned efforts of educators, and the question of whether reading itself is absolutely necessary to produce an informed, empathetic, and educated …

Investigating The Impact Of Gamification And Humor On Student Engagement In An Esl Classroom, Joshua F. Filipowski

Wellspring: A Practitioner-Oriented Journal of Literacy and Language Education

This study explores the impact of gamification and humor on middle school students' engagement, participation, and learning outcomes. The researcher, an ESL teacher, sought to address students' boredom and disengagement by introducing games and humor into the classroom. The study involved 12 middle school English learners and employed both qualitative and quantitative methods, including journal entries, focus groups, and participation tracking. Findings indicated that students were more engaged and willing to participate during gamified activities, with slight but significant improvements in quiz scores. Students expressed a preference for jokes and games over traditional methods. The research suggests that incorporating humor …

Exploring Embodied Learning: A Taxonomy Of Space, Sensation, And Movement, Leslie Bayers, Julaine Fowlin, Susan Hrach

SoTL Commons Conference

No abstract provided.