Digital Commons Network^™

Cognitive Control Processes In Behavior Therapy For Youth With Tourette’S Disorder, Joseph F. Mcguire, Alexandra Sturm, Emily J. Ricketts, Gabrielle E. Montalbano, Susanna Chang, Douglas W. Woods, James Mccracken, John Piacentini

Psychological Science Faculty Works

Background

Cognitive control processes are implicated in the behavioral treatment of Tourette’s disorder (TD). However, the influence of these processes on treatment outcomes has received minimal attention. This study examined whether cognitive control processes and/or tic suppression predicted reductions in tic severity and treatment response to behavior therapy.

Method

Fifty-three youth with TD or a pervasive tic disorder participated in a randomized wait list-controlled trial of behavior therapy. Following a baseline assessment to evaluate psychiatric diagnoses, tic severity, and cognitive control processes (e.g., response selection, inhibition, and suppression), youth were randomly assigned to receive eight sessions of behavior therapy ( …

Collective Cognitive Capital, Emily R. D. Murphy

William & Mary Law Review

This Article calls for a new project for law and neuroscience. It outlines a structural, not individual, application of brain and behavioral science that is aligned with the general goal of basic science research: improving the lives of citizens with a better understanding of the human experience. It asks brain and behavioral science to move explicitly into public policy territory, and specifically onto ground more traditionally occupied by economists—but in ways the project of “behavioral economics” has not yet ventured. Put simply, policy analysts should focus on brains—“collective cognitive capital”—with the same intensity with which they focus on money, rights, …

Using Burdens Of Proof To Allocate The Risk Of Error When Assessing Developmental Maturity Of Youthful Offenders, David L. Faigman, Kelsey Geiser

William & Mary Law Review

Behavioral and neuroscientific research provides a relatively clear window into the timing of developmental maturity from adolescence to early adulthood. We know with considerable confidence that, on average, sixteen-year-olds are less developmentally mature than nineteen-year-olds, who are less developmentally mature than twenty-three-year-olds, who are less developmentally mature than twenty-six-year-olds. However, in the context of a given case, the question presented might be whether a particular seventeen-year-old defendant convicted of murder is “developmentally mature enough” that a sentence of life without parole can be constitutionally imposed on him or her. While developmental maturity can be accurately measured in group data, it …

The Diversity Of Norm Psychologies: A Challenge For The Law, Paul Sheldon Davies

William & Mary Law Review

Can we craft a coherent set of laws applicable to populations with deep cultural diversity? The full force of this question—call it the generalization challenge—has emerged recently thanks to advances in the sciences of the human, especially theories of neuroscience and psychology framed by theories of biological and especially cultural evolution. The goal of this Article is to describe enough of those advances to make clear the force of the challenge. The motivation is simple: as we endeavor to imagine the future of law in light of discoveries in neuroscience and related disciplines, being apprised of the generalization challenge may …

Neuroscience And Criminal Justice: Time For A "Copernican Revolution"?, John S. Callender

William & Mary Law Review

The main purpose of this Article is to argue for a fundamental change in the conceptual orientation of criminal justice: from one based on concepts such as free will, desert, and moral responsibility, to one based on empirical science. The Article describes research in behavioral genetics, acquired brain injuries, and psychological traumatization in relation to criminality. This research has reached a level of development at which the traditional approach to criminality is no longer tenable and should be discarded. I argue that mental health legislation provides a model that could be adapted and applied to offenders.

Neuroscience, Criminal Sentencing, And Human Rights, Elizabeth Shaw

William & Mary Law Review

This Article discusses ways in which neuroscience should inform criminal sentencing in the future. Specifically, it compares the ethical permissibility of traditional forms of punishment, such as incarceration, on the one hand, and rehabilitative “neurointerventions” on the other. Rehabilitative neurointerventions are interventions that aim directly to modify brain activity in order to reduce reoffending. Various jurisdictions are already using techniques that could be classed as neurointerventions, and research suggests that, potentially, an even wider range of rehabilitative neurointerventions may be developed. This Article examines the role of human rights (in particular, the moral right to mental integrity and the legal …

Demonization Of Christians: Missiological Perspectives And Implications, Michée Badé

Journal of Adventist Mission Studies

This article is a missiological reflection on the phenomenon of Christian demonization from a Seventh-day Adventist (SDA) perspective. The article argues from the four voices approach in theology (see Cameron et al. 2010; Cameron and Duce 2013), and contends that Christians can be demonized, have been demonized throughout the Christian church history, and are still demonized today across all Christian denomination lines. This is the position that appears in a few SDA publications, and is not in contradiction with the Scriptures. I suggest that demonization and demon possession are etymologically and phenomenologically the same. Thus, this paper builds on the …

An Abductive Argument From Depression And Anxiety To Christian Personal Holiness, Kelly Douglas Burchett

Masters Theses

The science on pathological depression and anxiety (D&A) describes religion and spirituality's (R/S) insulating and immunizing effects in roughly 72 to 85 percent of all relevant articles. But the descriptivism of science cannot assign any normative value to a theological worldview. Deductive logic favors theism via Leibnizian contingency, Kalām cosmology, objective morality, fine-tuning of the universe, and abstract conceptualism. The information in DNA, the irreducible complexity of intracellular machinery, the improbability of folded proteins, and the support for common modular design over common ancestry establish a design inference for all of life. Unguided naturalistic simulations fail to surmount the complexity …

Naltrexone Implant For Opioid Use Disorder, Amber N. Edinoff, Catherine A. Nix, Claudia V. Orellana, Samantha M. Stpierre, Erin A. Crane, Blaine T. Bulloch, Elyse M. Cornett, Rachel L. Kozinn, Adam M. Kaye, Kevin S. Murnane, Alan David Kaye

School of Pharmacy Faculty Articles

The continued rise in the availability of illicit opioids and opioid-related deaths in the United States has left physicians, researchers, and lawmakers desperate for solutions to this ongoing epidemic. The research into therapeutic options for the treatment of opioid use disorder (OUD) began with the introduction of methadone in the 1960s. The approval of oral naltrexone initially showed much promise, as the drug was observed to be highly potent in antagonizing the effects of opioids while producing no opioid agonist effects of its own and having a favorable side effect profile. Patients that routinely take their naltrexone reported fewer days …

Revised Definition And Interpretations: Loans, Acquisitions, And Other Transactions, Et Sec. 0.400.06. 1.210.010, 1.224.010, 1.260.010, 1.260.020, And 1.270,010, American Institute Of Certified Public Accountants. Professional Ethics Division

AICPA Professional Standards

No abstract provided.

Revised Interpretation: Unpaid Fees, Et Sec. 1.230.010, American Institute Of Certified Public Accountants. Professional Ethics Division

AICPA Professional Standards

No abstract provided.

Inhalation Injury Is Associated With Endotheliopathy And Abnormal Fibrinolytic Phenotypes In Burn Patients: A Cohort Study, John W. Keyloun, Tuan D. Le, Kathleen E. Brummel-Ziedins, Melissa M. Mclawhorn, Maria C. Bravo, Thomas Orfeo, Laura S. Johnson, Lauren T. Moffatt, Anthony E. Pusateri, Jeffrey W. Shupp

School of Medicine Faculty Publications and Presentations

Burn injury is associated with endothelial dysfunction and coagulopathy and concomitant inhalation injury (IHI) increases morbidity and mortality. The aim of this work is to identify associations between IHI, coagulation homeostasis, vascular endothelium, and clinical outcomes in burn patients. One hundred and twelve patients presenting to a regional burn center were included in this retrospective cohort study. Whole blood was collected at set intervals from admission through 24 hours and underwent viscoelastic assay with rapid thromboelastography (rTEG). Syndecan-1 (SDC-1) on admission was quantified by ELISA. Patients were grouped by the presence (n = 28) or absence (n = 84) of …

Not-For-Profit Entities, March 1, 2022; Audit And Accounting Guide, American Institute Of Certified Public Accountants (Aicpa)

Industry Guides (AAGs), Risk Alerts, and Checklists

No abstract provided.

State And Local Governments, March 1, 2022; Audit And Accounting Guide, American Institute Of Certified Public Accountants (Aicpa)

Industry Guides (AAGs), Risk Alerts, and Checklists

No abstract provided.

Advertising Cross-Platform: Promotion Methods For Independent Musicians In The Era Of Live Streaming, Thomas Worrell

Honors Projects

A study of promotion techniques for independent musicians in the 21st century, after the covid-19 pandemic and the rise of live streaming. This paper looks at previous research on live streaming and promotion methods in the music industry, and combines that data with a survey of the public's perception of local music events. The results of this survey were used to promote and conduct a music concert that was viewable both in person and over live stream.

Nebraska Statewide Groundwater-Level Monitoring Report 2021, Aaron R. Young, Mark E. Burbach, Leslie M. Howard, Sue Olafsen Lackey, Robert Matthew Joeckel

Conservation and Survey Division: Faculty and Staff Publications

This report is a synthesis of groundwater-level monitoring programs in Nebraska. It is a continuation of the series of annual reports and maps produced by the Conservation and Survey Division (CSD) of the University of Nebraska in cooperation with the U.S. Geological Survey (USGS) since the 1950s. Groundwater-level monitoring began in Nebraska in 1930 in an effort to survey the state’s groundwater resources and to observe changes in its availability on a continuing basis. The CSD and USGS cooperatively developed, maintained, and operated an observation-well network throughout the state. These two agencies were responsible for collecting and archiving this information, …

Oedipus Der Tyrann: Zur Titelwahl Und Zum Begriff Des ›Tyrannen‹ In Hölderlins Übersetzung Des Sophokleischen Oedipus Tyrannus, Priscilla A. Hayden-Roy

German Language and Literature Papers

Zusammenfassung-- Im Jahr 1804 erschien Hölderlins zweibändige Übersetzung, Die Trauerspiele des Sophokles, bestehend aus Oedipus der Tyrann und Antigonae. Zeitgenossen haben u.a. die Titelwahl für seine Ödipus-Tragödie beanstandet, die, so ein Rezensent, gleich vorweg die mangelhaften Griechischkenntnisse des Übersetzers verrate. In diesem Aufsatz wird zunächst die Geschichte des Titels von Sophokles’ erster Ödipus-Tragödie skizziert, von der handschriftlichen Überlieferung bis hin zu volkssprachlichen Übersetzungen und Bearbeitungen, die vor 1805 im europäischen Raum erschienen sind. Der Fokus wird dann ausgeweitet auf die antike Bedeutung von tyrannos und Sophokles’ Verwendung von dieser und anderen Herrscherbezeichnungen in diesem Werk. Eine Analyse von …

Ambivalence Toward Bureaucracy: Responses From Korean School Principals, Hyun-Jun Joo, Taeyeon Kim

Department of Educational Administration: Faculty Publications

Purpose – Given the context of accountability-driven policy environments, research has shown that school leaders perceive bureaucratic rules and protocols in negative ways, but they also utilize organizational structures and routines to lead changes. To better understand both enabling and hindering mechanisms of bureaucracy in schools, this study explores how Korean school principals understand and perceive bureaucratic structures using a lens of ambivalence. The authors draw on Weber’s theory of bureaucracy, with a particular focus on the paradoxical aspect of bureaucracy that might be experienced by individuals within the system.

Design/methodology/approach – This study analyzed qualitative data collected from 26 …

Biogeosciences Perspectives On Integrated, Coordinated, Open, Networked (Icon) Science, D. Dwivedi, A. L.D. Santos, M. A. Barnard, T. M. Crimmins, A. Malhotra, K. A. Rod, K. S. Aho, S. M. Bell, B. Bomfim, F. Q. Brearley, H. Cadillo-Quiroz, J. Chen, C. M. Gough, E. B. Graham, C. R. Hakkenberg, L. Haygood, G. Koren, E. A. Lilleskov, L. K. Meredith, S. Naeher, Z. L. Nickerson, O. Pourret, H. S. Song, M. Stahl, N. Taş, R. Vargas, S. Weintraub-Leff

Department of Agricultural and Biological Systems Engineering: Faculty Publications

This article is composed of three independent commentaries about the state of Integrated, Coordinated, Open, Networked (ICON) principles in the American Geophysical Union Biogeosciences section, and discussion on the opportunities and challenges of adopting them. Each commentary focuses on a different topic: (a) Global collaboration, technology transfer, and application (Section 2), (b) Community engagement, community science, education, and stakeholder involvement (Section 3), and (c) Field, experimental, remote sensing, and real-time data research and application (Section 4). We discuss needs and strategies for implementing ICON and outline short- and long-term goals. The inclusion of global data and international community engagement are …

Instructional Models For Course-Based Research Experience (Cre) Teaching, David I. Hanauer, Mark J. Graham, Rachel J. Arnold, Mary A. Ayuk, Mitchell F. Balish, Andrea R. Beyer, Kristen A. Butela, Christine A. Byrum, Catherine P. Chia, Hui Min Chung, Kari L. Clase, Stephanie Conant, Roy J. Coomans, Tom D'Elia, Jason Diaz, Arturo Diaz, Jean A. Doty, Nicholas P. Edgington, Dustin C. Edwards, Elvira Eivazova, Christine B. Emmons, Kayla M. Fast, Viknesh Sivanathan, And About 50 Others

School of Biological Sciences: Faculty Publications

The course-based research experience (CRE) with its documented educational benefits is increasingly being implemented in science, technology, engineering, and mathematics education. This article reports on a study that was done over a period of 3 years to explicate the instructional processes involved in teaching an undergraduate CRE. One hundred and two instructors from the established and large multi-institutional SEA-PHAGES program were surveyed for their understanding of the aims and practices of CRE teaching. This was followed by large-scale feedback sessions with the cohort of instructors at the annual SEA Faculty Meeting and subsequently with a small focus group of expert …

Phenotypic And Genotypic Detection Of Carbapenemase Production Among Gram Negative Bacteria Isolated From Hospital Acquired Infections, Sreeja K. Vamsi, Rama S. Moorthy, Mary N. Hemiliamma, Deepak J. Chanderakant, Shravani Sirikonda

Saudi Medical Journal

Objectives: To identify the carbapenemase producing Gram-negative bacteria (GNB) by phenotypic methods and to confirm the presence of resistant genes using real-time polymerase chain reaction (PCR). Methods: This was a prospective study carried out at the Department of Microbiology, Sri Venkata Sai Medical College and Hospital, Mahabubnagar, India, from March 2018-2021. All samples were screened for carbapenem resistance by disc diffusion method and the VITEK ® 2 compact system (bioMérieux, France). Detection of carbapenemase was carried out using RAPIDEC ® CARBA NP test (Biomeriux Private Limited, South Delhi, India), screening for metallo-β-lactamases (MBL) was carried out by double disk synergy …

Apgar Values Lower Than 7 Associated With Mortality In Premature Newborns: A Retrospective Study, Nayeri Reyes-Saavedra, Patricia C. Castelán-Villagrana, Ivette Mata-Maqueda, Juan C. Solís-Sáinz

Saudi Medical Journal

Objectives: To determine the risk factors associated with mortality in premature newborns (PNB). Methods: An observational, descriptive, and retrospective study, carried out at the General Hospital of San Juan del Rio, Queretaro, Mexico. The medical records of PNB admitted to the Neonatal Intensive Care Unit from January until December 2018 were studied. Results: A total of 136 PNB were included (74 males and 62 females) of whom 16 (11.7%) died (9 males and 7 females). A correlation was observed between gestational age and birth weight with Apgar values at 1 and 5 minutes (r=0.37, p <0.001). A lower birth weight was found in premature infants with infectious diseases, as well as a lower gestational age in relation to respiratory diseases ( p <0.0001). The PNB with Apgar values lower than 7 points at 1 and 5 minutes were more likely to die ( p <0.0001). The PNB with very low birth weight (1-1.49 kg), with less than 28 weeks of gestation, and with infectious pathology showed more probabilities of dying ( p <0.05). Conclusion: Apgar values lower than 7 points in the PNB are associated with the presence of infectious diseases and mortality. Likewise, a lower gestational age represents a lower birth weight, with a higher risk for respiratory and infectious diseases, and consequently an elevated mortality.

Does Sars-Cov-2 Affect Cochlear Functions In Children?, Cigdem F. Koca, Turgut Celik, Agit Simsek, Sukru Aydin, Mehmet Kelles, Seyma Yasar, Omer Erdur

Saudi Medical Journal

Objectives: To determine the influence of coronavirus disease-19 (COVID-19) on cochlear tasks of children who had COVID-19 previously, and the relevance among disease seriousness and cochlear involvement by otoacoustic emissions (OAEs). Methods: The study included 24 hospitalized children after COVID-19 diagnosis, 23 pediatrics that received outpatient treatment, and 21 children who were without COVID-19 diagnosis as the control group between June 2021 and July 2021. Transient evoked otoacoustic emission (TEOAE), distortion product otoacoustic emission, and contrlateral suppression of otoacoustic emission measurements were carried out for each child. Symptoms of patients, the treatments they received, and the duration of hospitalization of …

Clinical Validation Of A Multiplex Pcr-Based Detection Assay Using Saliva Or Nasopharyngeal Samples For Sars-Cov-2, Influenza A And B, Nikhil S. Sahajpal, Ashis K. Mondal, Sudha Ananth, Allan Njau, Kimya Jones, Pankaj Ahluwalia, Eesha Oza, Ted M. Ross, Vamsi Kota, Arvind Kothandaraman

Pathology, East Africa

The COVID-19 pandemic has resulted in significant diversion of human and material resources to COVID-19 diagnostics, to the extent that influenza viruses and co-infection in COVID-19 patients remains undocumented and pose serious public-health consequences. We optimized and validated a highly sensitive RT-PCR based multiplex-assay for the detection of SARS-CoV-2, influenza A and B viruses in a single-test. This study evaluated clinical specimens (n = 1411), 1019 saliva and 392 nasopharyngeal swab (NPS), tested using two-assays: FDA-EUA approved SARS-CoV-2 assay that targets N and ORF1ab gene, and the PKamp-RT-PCR based assay that targets SARS-CoV-2, influenza viruses A and B. Of the …

Borderplex Business Barometer, Volume 6, Number 3, Thomas M. Fullerton Jr., Steven L. Fullerton

Border Region Modeling Project

No abstract provided.

Assessing Pre-Literacy Behaviors In Infants And Toddlers: Psychometric Evaluation Of The Infant Toddler Literacy Assessment (Itla-3), Barbara J. Jackson, Christine Marvin, Amy J. Encinger, Nicole Buchholz, Becky Zessin

Department of Special Education and Communication Disorders: Faculty Publications

Assessment of emerging literacy in young children is generally limited to either skill development in children over 3 years of age or the quality and context of young children’s early literacy experiences. Although there has been promotion of their early literacy experiences, assessment of emerging pre-literacy behaviors in children younger than 3 years has yet to be organized into a single tool.

Preliminary work on the Infant Toddler Literacy Assessment (ITLA) has progressed through initial steps of scale development and shown promise as a criterionbased, standardized assessment for tracking children’s pre-literacy behaviors and guiding practitioners in supporting development of those …

Consumer Search And Marketing Actions In Retailing, Yi Peng

Dissertations and Theses Collection (Open Access)

This dissertation seeks to gain insight into the critical roles of consumers and marketers in a retail context using a variety of unique and rich data sources (e.g., tracking data, retail scanner data, ad intel data and publicly available data). The main aim of the two essays is to focus on unique aspects of retail analytics. The first essay examines how consumers conduct haptic search to make purchase decisions using a unique dataset collected by the state-of-the-art sensing technology. This research contributes to the literature by defining key attributes of the shoppers’ speed, consideration set, and shopping path at the …

Studying Acetylation Of Aconitase Isozymes By Genetic Code Expansion, Jessica Araujo, Sara Ottinger, Sumana Venkat, Qinglei Gan, Chenguang Fan

Chemistry & Biochemistry Faculty Publications and Presentations

Aconitase catalyzes the second reaction of the tricarboxylic acid cycle, the reversible conversion of citrate and isocitrate. Escherichia coli has two isoforms of aconitase, AcnA and AcnB. Acetylomic studies have identified acetylation at multiple lysine sites of both E. coli aconitase isozymes, but the impacts of acetylation on aconitases are unknown. In this study, we applied the genetic code expansion approach to produce 14 site-specifically acetylated aconitase variants. Enzyme assays and kinetic analyses showed that acetylation of AcnA K684 decreased the enzyme activity, while acetylation of AcnB K567 increased the enzyme activity. Further in vitro acetylation and deacetylation assays were …

Allen Ginsberg In Cedar Falls: Beatniks, Socialists, And “All That Hair”, Roy R. Behrens

Faculty Publications

No abstract provided.

Fires On Ice: Emerging Permafrost Peatlands Fire Regimes In Russia’S Subarctic Taiga, Vera Kuklina, Oleg Sizov, Elena Rasputina, Irina Bilichenko, Natalia Krasnoshtanova, Viktor Bogdanov, Andrey N. Petrov

Faculty Publications

Wildfires in permafrost areas, including smoldering fires (e.g., “zombie fires”), have increasingly become a concern in the Arctic and subarctic. Their detection is difficult and requires ground truthing. Local and Indigenous knowledge are becoming useful sources of information that could guide future research and wildfire management. This paper focuses on permafrost peatland fires in the Siberian subarctic taiga linked to local communities and their infrastructure. It presents the results of field studies in Evenki and old-settler communities of Tokma and Khanda in the Irkutsk region of Russia in conjunction with concurrent remote sensing data analysis. The study areas located in …