Digital Commons Network^™

Understanding Atomoxetine Exposure Variability In Children And Adolescents With Adhd Through Population Pharmacokinetics., Kevin V. Tobin, Addison M. Pritchett Ms, J Steven Leeder, Joga Gobburu, Allison Dunn

Manuscripts, Articles, Book Chapters and Other Papers

Atomoxetine, a selective norepinephrine reuptake inhibitor, is a nonstimulant alternative to treat attention-deficit/hyperactivity disorder in children and adolescents. Atomoxetine exposure is highly variable due to cytochrome P450 polymorphism; however, the impact of these genetic variations has not been adequately characterized in the pediatric population. A population pharmacokinetic (PK) model was developed to evaluate steady-state atomoxetine exposures after oral administration in a large, heterogeneous population of children and adolescents with different metabolic phenotypes. Due to the highly variable and complex absorption between subjects and occasions, a two-stage approach was implemented, treating each participant/occasion as a separate individual. First, the individual atomoxetine …

Cd8 Trm-Like T Cells Expressing Perforin And Ifn-Γ Define A Pediatric Activated T-Cell Acute Liver Failure Endotype., Tamir Diamond, Catherine A. Chapin, Caroline J. Diorio, Sarah Mccuaig, Michelle Lau, Niansheng Chu, Nora M. Gibson, Portia A. Kreiger, Simon Horslen, Kathleen M. Loomes, Anna M. Banc-Husu, Jaime Chu, M Kyle Jensen, Daniel H. Leung, Amrita Narang, Beth A. Carter, Scott Elisofon, Ryan T. Fischer, Steven J. Lobritto, Mike Leonis, Anna L. Peters, Norberto Rodriguez-Baez, Rene Romero, Philip Rosenthal, David Rudnick, James Squires, Shikha Sundaram, Kyla M. Tolliver, Pamela Valentino, Valerie Durkalski, Estella M. Alonso, Edward M. Behrens

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Activated T-cell pediatric acute liver failure (TC-PALF) is the most common cause of non-acetaminophen PALF, with poor transplant-free survival. Livers in TC-PALF are infiltrated by effector cytotoxic T lymphocytes with markers of tissue-resident memory function (CD8 Trm) and an interferon gamma (IFNγ) transcriptional signature. The PALF-Immune Response Network (PALF-IRN) and the prospective TReatment for ImmUne-Mediated PathopHysiology (TRIUMPH) clinical trial (NCT04862221) aim to characterize the TC-PALF immune pathology and utility of T-cell directed therapy to improve transplant-free survival.

METHODS: TRIUMPH patients with TC-PALF were compared with healthy children and disease controls utilizing multiparameter flow cytometry and 3' single-cell RNA sequencing …

Factors Associated With Child Protective Services Referrals In Young Children With Isolated Skull Fractures., Karli Breeden-Carino, Joanne N. Wood, Cindy W. Christian, Tagrid M. Ruiz-Maldonado, Daniel M. Lindberg, Angela Bachim, Lori Frasier, Terra N. Frazier, Nancy S. Harper, Sara E. Kruczek, Farah Brink, Jennifer E. Wolford, Jan Leonard, M Katherine Henry

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: Many young children with isolated skull fractures are referred to child protective services (CPS) despite being assessed to have a low likelihood of abuse. We sought to identify factors associated with CPS referrals in this population and to quantify hospital-level variation.

METHODS: We performed a multicenter retrospective cross-sectional study of children < 2 years with skull fractures with or without a small underlying intracranial hemorrhage (ICH) and no additional injuries undergoing a child abuse pediatrics (CAP) subspecialty evaluation. We explored associations between demographic factors, clinical characteristics, psychosocial risk factors, and hospital site with CPS referral status. We performed multivariable logistic regression, adjusting for transfer status and all significant covariates from unadjusted analyses. We utilized marginal standardization to calculate the estimated probability of CPS referrals at each site, adjusting for all factors in the final model.

RESULTS: Of 528 children, 303 (57.4%) were referred to CPS, with 86.5% referred before CAP consultation. In multivariable logistic regression, presence of psychosocial risk factors (OR 4.00; 95% CI 2.25, 7.11), in-person CAP consult (OR 3.93; 1.61, 9.62), inflicted or no trauma history provided (OR 6.15; 3.30, 11.45), …

Confessions In Cases Of Child Physical Abuse-A Capnet Study., Margaret R. Russell, Antoinette L. Laskey, Henry T. Puls, Suzanne P. Starling, Joanne N. Wood, Daniel M. Lindberg, Nancy S. Harper, Caitlin R. Mcnamara, Angela W. Bachim, Farah W. Brink, Lori D. Frasier, James Anderst, Porcia Vaughn, Kristine A. Campbell

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: Prior research on confessions of physical abuse (PA) has explored mechanisms of injury. Little is known about conditions supporting a confession of abuse or how confessions may influence case outcomes.

METHODS: This cross-sectional study of suspected PA in children aged < 10 years at 10 centers participating in CAPNET, a multicenter child PA research network, included children with in-person Child Abuse Pediatrics (CAP) consultations between February 2021 and December 2022 and excluded children without injury. Our focus was a confession of inflicted injury known to the CAP during clinical involvement. We compared child and clinical characteristics, out-of-home (OOH) placements, and arrests between cases with and without confessions. Multivariable models using generalized estimating equations (GEE) produced adjusted predicted probabilities (APP) clustering by CAPNET site.

RESULTS: Confessions were known to CAPs in 115/4297 (2.7%) cases, with significant site variability. In a multivariable GEE model, confessions were more likely in cases with injuries with high specificity for abuse (APP 6.0% vs 1.6%, P < .001), near-fatality (APP 5.6% vs 2.3%, P < .001), and older children (APP 4.8% vs 2.5%, P = .025). OOH placements and arrests were more common in cases with confessions. CAP awareness of confessions, OOH placements, and arrests did not follow racial or ethnic patterns seen in the US child welfare system. Lower socioeconomic status was associated with OOH placements and arrests but not with CAP awareness of confessions.

CONCLUSIONS: Our findings highlight differences in case characteristics and outcomes where a confession is known to the CAP and raise questions about …

Exploitive Adolescent Labor And Labor Trafficking: Clinical Perspectives For Adolescent Healthcare Providers., Romina Barral, Michele A. Kelley, Abigail English, Marissa Raymond-Flesch, Tonya Chaffee, Veronica Svetaz, Tamera Coyne-Beasley, Nuray Kanbur

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Sialylation In The Nervous System: Functions And Mechanisms., Kate Koles, Elena Repnikova, Boris Novikov, Vladislav Panin

Manuscripts, Articles, Book Chapters and Other Papers

Glycoprotein sialylation represents a critical posttranslational modification with diverse biological roles in animals. This review explores its multifaceted functions in the nervous system, with particular emphasis on neurophysiology, homeostasis, and associated neurological disorders. The sialylation pathway modulates key neural processes through effects on glycoprotein stability, localization, activity, and molecular interactions. Examples include its crucial role in the regulation of neuronal excitability by modulating the functions of voltage-gated ion channels. Recent studies have uncovered remarkably rapid, activity-dependent changes in synaptic sialylation, suggesting dynamic sialylation-mediated regulation of neural transmission and highlighting the importance of neuraminidases in these processes. Beyond synaptic function, sialylation …

Protocol For Non-Invasive Assessment Of Skeletal Muscle Structure And Function In Adolescents With Single Ventricle Heart Disease: A Cross-Sectional, Case-Control Study., Tyler A. Fick, Trent J. Herda, Emily Cramer, David A. White, Daniel Forsha

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Congenital heart disease (CHD) is the most common congenital malformation, and the most severe type, single ventricle (SV) heart disease, requires the Fontan surgical palliation. Fontan palliation minimizes hypoxemia and volume overload by separating systemic and pulmonary circulations, resulting in the absence of a sub-pulmonary pump. Skeletal muscle health may have a greater relative contribution to overall functional capacity of those with SV physiology, via the skeletal muscle (SkM) pump mechanism and oxidative capacity. The purpose of this study is to comprehensively evaluate multiple domains of SkM in this population compared to those with normal cardiac anatomy.

METHODS: Forty …

Neighborhood Physical Disinvestment And Incident Diabetes Between Visits 1 And 2 Of The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol)., Cara M. Smith, Elizabeth W. Spalt, Linda C. Gallo, Jordan A. Carlson, Matthew Allison, Bharat Thyagarajan, Earle C. Chambers, Amber Pirzada, Martha Daviglus, Christina Cordero, Qibin Qi, Elena Austin, Amanda M. Fretts, India Ornelas, Robert Kaplan, Joel D. Kaufman, Stephen J. Mooney

Manuscripts, Articles, Book Chapters and Other Papers

Neighborhood-scale environmental factors, including disinvestment in infrastructure, may impact cardiometabolic disease risk. To our knowledge, no prior studies have investigated the association between neighborhood disinvestment and incident diabetes. We used a virtual street audit of Google Street View Imagery to generate a neighborhood disinvestment score for participants' residential addresses in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). An item response theory model was fit to indicators (litter, graffiti, under-maintained buildings, bars on windows, and abandoned buildings) to form a scale measuring a latent level of disinvestment. Ordinary kriging was used to estimate levels for each residential address within the …

Accurate Predictions Of Disordered Protein Ensembles With Starling, Borna Novak, Jeffrey M Lotthammer, Ryan J Emenecker, Alex S Holehouse

2020-Current year OA Pubs

Intrinsically disordered proteins and regions (collectively IDRs) are found across all kingdoms of life and have critical roles in virtually every eukaryotic cellular process

Repurposing Glp-1ra Drugs For Modulating Sepsis-Associated Encephalopathy And Neurodegeneration, Janhavi Tonge

Undergraduate Student Symposium

Sepsis, a life-threatening disorder caused by an exacerbated immune host response towards a pathogen, accounts for about 1 in 5 deaths worldwide with more than 11 million deaths. In septic pathophysiology, pathogen components interact with the receptors of immune and endothelial cells, causing the release of inflammatory signals. This results in a hyperinflammatory phase that leads to "leaky" blood vessels through vasodilation, which causes improper tissue perfusion and hypotension. If untreated, this can lead to multiorgan damage and can be especially damaging to vulnerable, non-regenerative organs such as the brain. Post-sepsis recovery has long term consequences in the central nervous …

From Resume To Risk Factor: The Connections Between Occupation, Chronic Disease, And Mental Health In The United States, Nemo Thomas, Joshua Dumond, Nicole Real

Undergraduate Student Symposium

Mental health affects various aspects of overall health, including physical, emotional, and social well-being, which influences behavior and management of disease. Furthermore, occupational types (blue-collar, white-collar, and grey-collar) can influence how individuals manage stress. This can be due to the various responsibilities an individual has or the work environment that one is consistently exposed to, which can lead to detrimental mental health outcomes. This study examined the relationship between occupational type and the occurrence of individuals' self-reported levels of distress, anxiety, hopelessness, restlessness, sadness, and worthlessness. The data from this study was obtained from the IPUMS NHIS 2024 surveys, a …

Psychological Separation As A Developmental Moderator Of Cognitive Maladjustment, Tanvi Rudrangi, Kaleigh Cummings, Misha Patel

Undergraduate Student Symposium

Developing a personal identity is a central task of late adolescence (Erikson, 1968). Emerging adulthood, a developmental period spanning the late teens to mid-twenties, is characterized by increased independence and self-focus, providing opportunities for life skill development and self-understanding. Despite this emphasis on self-focus, emerging adults' psychosocial adjustment remains closely tied to parent relationships, particularly the process of separation-individuation from parents. The present study examined whether paternal psychological separation moderates the relationship between self-focused life perspectives and maladaptive cognitions of ego inflation/superiority. Participants included 95 emerging adults (ages 18-25, M=20.7, 60 women). Paternal separation was assessed using the 69-item Psychological …

Trail-Camera Monitoring Of Gopher Tortoise Burrows And The Commensal Wildlife Across South Florida Natural Areas, Madison Smith, Heidi Martz, Coral Kovac, Olivia Baker, Javier Vasallo, Jade Andreu

Undergraduate Student Symposium

Gopher tortoises (Gopherus polyphemus) are a keystone species whose burrows provide essential shelter for numerous commensal organisms in Florida's upland ecosystems. Understanding tortoise behavior and the wildlife activity that occurs around burrow entrances is critical for informing conservation management and public outreach. This project used motion-triggered trail cameras to document gopher tortoise activity and burrow-associated wildlife across multiple protected natural areas in South Florida. At each natural area, three active burrows were selected and monitored, resulting in three trail cameras deployed per site and nine cameras deployed in total. All cameras operated continuously over an extended observation period. …

Effects Of Renin-Angiotensin System Targeting Drugs On Cerebral Amyloid Angiopathy And Related Neuropathology, Anna Maria Weber, Ariana Hernandez, Chana Vogel, Victoria Pulido-Correa, Maria Agustina Paiz, Shaina Binu, Sonakshi Kose, Aayush Doshi, Dylan Kuni, Sylvia Yousef

Undergraduate Student Symposium

Cerebral amyloid angiopathy (CAA) is a common cerebrovascular disease characterized by beta-amyloid (Aβ) accumulation in the cerebral vasculature, resulting in vascular cognitive impairment and dementia (VCID) along with other neuropathologies such as inflammation. Given that medications approved to treat CAA currently do not exist, this highlights that there is a pressing need for more innovative approaches to drug discovery. In this study, classical renin-angiotensin system (RAS)-inhibiting antihypertensive drugs were repurposed to investigate their efficacy for mitigating CAA-associated neuropathology and cognitive decline, while additionally evaluating for sex-specific outcomes. Male and female Tg-SwDI mice were treated for 4 months with non-hypotensive doses …

The Functional Movement Screening In Collegiate Soccer Players, Sophia White, Karina Manrique

Undergraduate Student Symposium

About 70% of soccer injuries are non-contact, resulting from underlying mobility, stability, or movement pattern issues. Soccer players are particularly susceptible to ankle, knee, and hip injuries due to the high demands on lower body mobility, stability and repetitive dynamic motions. Functional Movement Screening is a popular evaluation method that is used to find asymmetries and dysfunctional movement patterns that could put athletes at risk for injury. Scores from the FMS test have been linked to injury risks. The purpose of this study is to conduct and evaluate the FMS performances among collegiate soccer players (n=26) to decrease injury risk, …

Evaluting Practical Limitations Of Signal Detection Theory In Clinical Behavioral Research, Xinlei Zhang, Prarthana Harikrishnan

Undergraduate Student Symposium

Deficits in inhibitory control - the ability to suppress automatic, impulsive responses - has been widely considered as a potential biomarker for mental health disorders. Signal Detection Theory (SDT) has provided a systematic measurement method for inhibitory control in clinical behavioral assessment. To evaluate the feasibility of inhibitory control as a biomarker, researchers have used meta-analysis to examine its effect size (Hedge's g) in differentiating between individuals with mental health disorders and healthy controls. Values of g>0.8 indicate that inhibitory control may serve as a clinically useful biomarker for distinguishing patients from healthy individuals, whereas g<0.8 suggests limited clinical utility. However, our study found that a limitation of SDT - its lack of reliability when participants show perfect performance - would lead to distorted and misleading results when evaluating the efficacy of inhibitory control as a biomarker. In our computational simulation, we found that when applying SDT to a clinically useful biomarker (for example, true effect size g = …

Resilience Factors For Physical Activity After Completion Of Intensive Interdisciplinary Pain Treatment: A Qualitative Analysis., William R. Black, Lora L. Black, Jennifer Christofferson, Liesbet Goubert, Cara M. Hoffart, Dustin Wallace

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVES: This study explored potential resilience factors that facilitate engagement in physical activity (PA) among adolescents with chronic musculoskeletal pain after completing intensive interdisciplinary pain treatment.

METHODS: Ten adolescents aged 13 to 17 years with a history of chronic musculoskeletal pain from a mid-western pediatric hospital in the United States participated in this qualitative study. Participants provided demographic information and completed semistructured virtual interviews. The interviews focused on their pain experiences, resilience, and engagement in PA. Transcripts were analyzed using primarily directed content analysis based on a pain resilience framework.

RESULTS: Participants highlighted several key resilience factors that influenced their …

Assessment Of The Adequacy Of The Fast Healthcare Interoperability Resources (Fhir) Genomics Standard For The Representation Of Somatic Testing Reports., Robert H. Dolin, Bret S E Heale, James Patterson, Kevin Power, May Terry, Howard Anton, James Chen, Kashmira Sawant, Srikar Chamala

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVES: Enabling the unambiguous communication of cancer genetic testing results and the corresponding therapeutic implications of identified genetic variants is of major clinical importance. In this report, we assess the adequacy of the Health Level Seven Fast Healthcare Interoperability Resources (FHIR) Genomics Reporting Implementation Guide, version 3 (also known as "FHIR Genomics") for the structured communication of semantic objects typically appearing in real-world somatic testing reports.

MATERIALS AND METHODS: The GenomeX project team, part of the CodeX FHIR Accelerator, performed the following assessment: (1) gather a convenience sample of public somatic reports; (2) create a representative somatic report that includes …

Buried Identities: Analyzing Maya Gender Roles Through Burials At Chan Chich, Belize, Nicole Watson

Student Publications

The site of Chan Chich, Belize, has undergone excavations since 1996, but there has been little attention given to the question of gender. Burial analyses serve as the most fruitful way to comprehend gender inequalities and differences at Chan Chich, and this paper examines every burial excavated at the site since its first field season. The findings show evidence for elite women engaging in craft production and ritual activities, while also receiving immense care and effort in their burial constructions. Although there is limited data to work with, it is clear that some women held essential responsibilities and gained respect …

Investigating The Structural And Functional Roles Of Transcriptionally Active Rice Transposons, Eimaan Admad

Undergraduate Student Symposium

Transposable elements (TEs) are crucial contributors to genome dynamics, evolution, gene structure, and regulation of gene expression. Once considered "junk DNA," TEs are now recognized for their significant roles in genome function and organization. TEs are epigenetically regulated through chromatin modifications, genomic imprinting, and the production of small RNAs and long non-coding RNAs (lncRNAs), which in turn can influence gene expression. Despite a wealth of data from sequencing projects advancing TE research, their large size—often exceeding the read lengths of many sequencing platforms—has limited comprehensive analysis. Moreover, the high copy number and sequence similarity (often >80%) within TE families can …

The Role Of Hip Internal Rotation And Ground Reaction Forces On Lower Back Pain In Amateur Golfers, Katrina Arndt

Undergraduate Student Symposium

Lower back pain (LBP) is the most common musculoskeletal injury amongst golfers; the high velocity and repetitive motion of the golf swing on the lumbar spine leads to substantial compressive and torsional forces, making LBP primarily and overuse injury. An additional risk factor for LBP is limited lead hip internal rotation (LHIR), which forces the lumbar spine to compensate through excessive rotation. The golf swing also relies heavily on the efficient transfer of energy generated from the ground through the lower body, a process quantified by ground reaction forces (GRFs). While existing research has separately examined LBP and GRFs, there …

Effects Of Invasive Water Hyacinth On Boldness And Habitat Preference In Mosquitofish, Nicolas Borca, Chancellor Rockwell Marks

Undergraduate Student Symposium

Eastern mosquitofish (Gambusia holbrooki) are small freshwater fish that play an important role in aquatic food webs. Their behavior, especially boldness and risk-taking, can change depending on the type of habitat they occupy. In this study, we investigated how mosquitofish respond behaviorally to the presence of the floating invasive plant water hyacinth by comparing their boldness, preference for cover, and predation rates between water hyacinth and its native competitor, pennywort. Fish boldness was measured using a two-factor latency experiment. Fish were collected from freshwater locations in South Florida that either had the invasive plant or were free of …

Porites Coral Colony Recovery At Caño Island , Sophia Bost

Undergraduate Student Symposium

Coral reefs are essential marine ecosystems and Porites lobata is an important Eastern Pacific reef-building coral that plays a major role in reef structure and ecosystem stability. This project documents Porites lobata responses to impacts associated witl1 the 2023-24 El NiÑo-Southern Oscillation, comparing coral tissue condition from 2024 and 2025. Overlapping digital images (~500 each year) utilizing two GoPro Hero 11 cameras were obtained from one, large (~13 m²) Porites lobata colony at Caño Island, Costa Rica. The program Agisoft Metashape was used to generate a 3D photogrammetry model constructed from these digital images. Living, bleached and dead …

Analysis Of Accuracy In Ecgs Data Captured By Patients Using At-Home Ai-Assisted Device Compared To Qualified Clinician Recordings, Snehana Chinnola, Colin Pulickathadam

Undergraduate Student Symposium

Cardiovascular Diseases (CVDs) are a leading cause of death worldwide, accounting for 17.3 million deaths per year. Recent advancements in artificial intelligence (AI) introduce promising opportunities in the field of cardiology to support healthcare services outside traditional clinical settings. At-home care generally promotes patient independence and improved health outcomes, while staying cost-effective due to decreased hospital visits. This study will analyze deidentified patient pilot data to assess the feasibility and performance of AI-assisted at-home electrocardiogram (ECG) monitoring compared with standard clinician-obtained ECGs during routine clinical visits, focusing on signal quality and accuracy. Additionally, the data consistency will be examined to …

Targeting The Metabolic-Neurodegenerative Axis: In Silico Repurposing Of Fda-Approved Pleiotropic Metabolic Modulators For Alzheimer's Tau Protein, Maanya Chitrapu, Juhi Vora

Undergraduate Student Symposium

Extensive research has established a link between insulin deficiency and insulin resistance and Alzheimer's Disease (AD) type-neurodegeneration, coining it "Type 3 Diabetes". While research typically focuses on glucose regulation, the comparative structural efficacy of broader metabolic agents against neuropathology remains distinctively underexplored. This study addresses this gap by performing a novel in silico comparison of three drug classes (Glucose, Lipid, and Cardio-Metabolic regulators) to identify superior scaffolds for obstructing the pathological Tau protein, which plays a major role in causing AD through its hyperphosphorylation. The Tau paired helical filament (PDB ID: 5O3L) was retrieved from the RCSB Protein Data Bank. …

Transcranial Magnetic Stimulation For Substance Use Disorder, Sarah Defrant

Undergraduate Student Symposium

This review evaluates transcranial magnetic stimulation (TMS) as a supplemental intervention for decreasing substance use disorder (SUD) relapse rates by synthesizing understandings of neurobiological mechanisms and clinical outcomes. TMS stimulates the activity of neural cells in the dorsolateral prefrontal cortex (DLPFC), a small portion of the prefrontal cortex that houses impulse control and decision-making skills. This leads to improved neuroplasticity and dopamine regulation, both of which are disrupted by unregulated substance use. Although TMS is not FDA-approved for substance use disorder, the neurobiological similarities between SUD and its comorbidities like major depressive disorder or anxiety highlight TMS's theoretical potential to …

Distinct And Cooperative Effects Of Epigenetic Inhibitors On Cell Viability And Cell Cycle Regulation In Neuroblastoma Cells, Tamanna Dipen Shah, Anushka Ayanampudi, Shyam Jaganathan

Undergraduate Student Symposium

Epigenetic dysregulation plays a central role in uncontrolled cell proliferation and therapeutic resistance in cancer. Consequently, targeting epigenetic regulators with small-molecule inhibitors has emerged as a promising strategy to disrupt cell cycle progression and induce tumor cell death. In this study, we evaluated the cytotoxic and molecular effects of two epigenetic-targeting agents, CM-272 and JNJ-64619178, administered as individual, simultaneous, and sequential treatments in neuroblastoma cell models. Cell viability was assessed using XTT assays, and changes in cell cycle regulatory proteins were analyze by Western blotting. Our results demonstrate that simultaneous combination treatment produced the greatest reduction in cell viability compared …

Environmental Exposure And Neighborhood Change: A Longitudinal Study Of Little Haiti, Miami, Joshua Dumond

Undergraduate Student Symposium

Urban development trends in coastal cities are increasingly impacted by environmental characteristics like elevation. As individuals and businesses residing near the coast move inland to escape rising sea levels, climate-resilient communities may begin to experience increased housing market trends and real estate investment. This longitudinal, retrospective study investigates how elevation influences the housing market in higher-ground communities, with a focus on the Little Haiti neighborhood in Miami, Florida, while also describing changes in demographic characteristics over time. Census tracts within Little Haiti were used as the unit of analysis for this study while using the U.S. Geological Survey Data to …

Proximal Power Gains In Football: Position-Specific Adaptations Revealed Through Compositional Data Analysis, Isabella Estrada Hernandez, Alyana Andal

Undergraduate Student Symposium

Training-induced adaptations in joint power distribution during speed running may enhance performance, but how these changes manifest across different American football position groups remains poorly understood. We investigated the influence of training and player position on joint power composition among players training for the National Football League draft. Forty-eight draft-eligible players performed pre- and post-training camp running trials at 23.4 km/h. We used motion capture software and MATLAB to calculate bilateral peak hip, knee, and ankle joint power. Compositional data analysis (CoDA) was used, in which positive/generated and negative/absorbed power compositions were expressed as isometric log-rations: hip versus knee + …

Baseline Emotional Valence Predicts Subsequent Executive Function Task Performance, Andrea Fajardo Aguilar, Alyssa Harris, Isidora Varas-Sanchez, Julia Ribeiro, Dylan Kuni

Undergraduate Student Symposium

Executive functioning (EF) supports goal-directed behavior and is influenced by affective state. While prior research has largely focused on the effects of emotional valence during task performance, less is known about the influence of pre-task self-reported valence on subsequent EF performance. Our ongoing study will examine whether self-reported ratings of emotional valence assessed prior to the start of a task will predict performance. Participants will report valence ratings during a resting baseline period before performing two EF tasks: the Vertical Stroop and the Go/No-Go. Performance will be assessed using reaction time and accuracy. Regression analyses will be conducted to …