Digital Commons Network^™

Is Left Ventricular Dysfunction Associated With Increased Risk Of Alzheimer's Disease Independent Of Classical Vascular Dementia Pathways?, Priyanshi Patel

Undergraduate Student Symposium

This poster examines the potential connection between left ventricular dysfunction and the risk of Alzheimer's disease in older adults. Studies suggest that reduced heart function may affect brain health by limiting blood flow to the brain, increasing inflammation, and interfering with the brain's ability to clear harmful proteins such as amyloid-β and tau. These processes resemble changes commonly seen in Alzheimer's disease. In population-based studies, individuals with heart failure or structural abnormalities of the left ventricle appear to have a higher risk of developing dementia, including Alzheimer's disease, even after accounting for major risk factors such as hypertension and clinical …

Analysis Of Conserved Domains In Promoters Of Differentially Expressed Genes In Rice, Mahalaxmi Some, Eimaan Ahmad, Emalynn Tobias

Undergraduate Student Symposium

Plant responses to stress involve changes in gene expression, and understanding these changes is key to improving crop resilience. A critical step in this process is identifying "conserved domains" in the promoters of Differentially Expressed Genes (DEGs), as these domains often provide binding sites for transcription factors. In this study, we aim to identify the Cis-Regulatory Elements (CREs) in the promoters of DEGs associated with heat stress. Previously, we identified 149 DEGs from transcriptomic analyses of two rice varieties, Cypress (heat-tolerant) and LaGrue (heat-sensitive), both exposed to high night temperatures (HNT; 82.4 ± 1°F or 28 ± 1°C). We hypothesize …

Effects Of Renin-Angiotensin System Targeting Drugs On Cerebral Amyloid Angiopathy And Related Neuropathology, Anna Maria Weber, Ariana Hernandez, Chana Vogel, Victoria Pulido-Correa, Maria Agustina Paiz, Shaina Binu, Sonakshi Kose, Aayush Doshi, Dylan Kuni, Sylvia Yousef

Undergraduate Student Symposium

Cerebral amyloid angiopathy (CAA) is a common cerebrovascular disease characterized by beta-amyloid (Aβ) accumulation in the cerebral vasculature, resulting in vascular cognitive impairment and dementia (VCID) along with other neuropathologies such as inflammation. Given that medications approved to treat CAA currently do not exist, this highlights that there is a pressing need for more innovative approaches to drug discovery. In this study, classical renin-angiotensin system (RAS)-inhibiting antihypertensive drugs were repurposed to investigate their efficacy for mitigating CAA-associated neuropathology and cognitive decline, while additionally evaluating for sex-specific outcomes. Male and female Tg-SwDI mice were treated for 4 months with non-hypotensive doses …

Colon Cancer Findings And A Community Solution, Brintia Wright

Undergraduate Student Symposium

Colorectal cancer remains a significant public health concern due to its high incidence, mortality, and persistent demographic disparities. The primary goal of this project was to develop an evidence-based community resource guide for the South Florida region to support early detection and equitable screening for colon cancer. The resource guide was informed by a structured review of current screening guidelines, peer-reviewed literature, and population-level data from the Surveillance, Epidemiology, and End Results (SEER) program. SEER incidence, stage at diagnosis, and survival data for individuals aged 25-84 years diagnosed with colon cancer between 2000 and 2022 were synthesized to identify high-risk …

The Impact Of Social Determinants Of Health On The Emotional Well-Being Of Lgbtq Young Adults, Bridget J. Mantooth-Urso

Electronic Theses and Dissertations 2020 - Present

The current study examined whether neighborhood-based social determinants of health (SDOH) were associated with emotional health outcomes among sexual minority young adults ages 18–29, and whether perceived social support mediated this relationship. SDOH refers to the conditions in which individuals are born, grow, live, work, and age, including neighborhood and built environment characteristics that shape access to resources, safety, and well-being. Emotional health in this study was operationalized through self-reported symptoms of depression and anxiety, while social support represented perceived availability and quality of interpersonal resources that may buffer the impact of structural disadvantage. This study utilized a non-experimental, cross-sectional …

The Territorial Continuum: American Samoa, Criminal Adjudication, And Territorial Administration, Emmanuel Hiram Arnaud

Cardozo Law Review

The standard account of American territorial expansion posits that territorial acquisition moved along a spectrum of sovereignty. The federal government acquired new inhabited land through conquest or purchase, and the Constitution tasked Congress with organizing and administering the new territories until they were ready to become states. That pattern came to an abrupt halt in 1898 when, at the conclusion of the Spanish-American War, the Supreme Court, fearing the extension of citizenship to and the permanent integration of non-White populations into the American polity, suddenly pronounced that the Constitution authorized the holding of colonies. The Court thus sentenced new territories, …

Hyperbole In The Capital Stack: Are We Misreading Lender Intent? Liability Management Transactions And The Implied Covenant Of Good Faith And Fair Dealing, Daniel R. Janel

Cardozo Law Review

The hasty characterization and overall sentiment surrounding Liability Management Transactions (“LMTs”) as “hostile” strategies that promote “lender-on-lender violence” attempt to misapply the implied covenant of good faith and fair dealing under New York law, which serves as a gap-filler rather than a “contract buster.” Although the covenant’s proper function is to protect parties’ reasonable expectations that they will receive the fruits of their bargain, it does not purport to rewrite or impose on carefully negotiated credit agreements. Sophisticated parties enter into meticulously crafted credit agreements with full awareness of the breadth and scope of their provisions. Only after finding themselves …

From Waiver To Shield: The Routine Misapplication Of The Federal Tort Claims Act’S Discretionary Function Exception, Alexander Sitnikov

Cardozo Law Review

When a pedestrian trips and falls on a defective sidewalk, liability usually turns on negligence. But when the property surrounding the sidewalk belongs to the federal government, tort liability often vanishes altogether. This result is just one of the many shortcomings of the Federal Tort Claims Act (FTCA) and one of its most controversial and heavily litigated provisions: the discretionary function exception (“DFE”). This Note explores the current judicial interpretations of the FTCA and DFE, which often work in conjunction with state laws and federal regulations. Despite the central public policy rationale and congressional intent surrounding the FTCA and its …

Conscripts, Convicts, And Contractors: Ersatz Soldiers And Russia's Total Mobilization Workarounds, Tad A. Schnaufer Ii, Guido Rossi

Journal of Strategic Security

The large-scale conventional conflict in Ukraine has absorbed hundreds of thousands of soldiers on both sides. Yet, domestic considerations have limited mobilization of citizens into the military at the devastating cost of prolonging the conflict. The 2022 Russian invasion force should have comprised far more personnel to ensure success at the outset. Russian leadership grossly underestimated the Ukrainian will to resist and vastly overestimated its own capabilities. Once the initial attack failed, both Russia and Ukraine only incrementally mobilized their populations, leaving neither side with overwhelming strength to create a breakthrough that would end the war. Hence, the ongoing slog …

Push And Pull: Nato, Eu, And Poland’S Positioning After 2022, Zsombor Zeöld, Réka Dobreffné Bogár, Dániel Bernát Vay

Journal of Strategic Security

The 2022 Russia-Ukraine war profoundly reshaped European security, exposing long-standing weaknesses while accelerating institutional adaptation within the North Atlantic Treaty Organization (NATO) and the European Union (EU). This article argues that NATO reaffirmed its role as the guarantor of hard deterrence and defense commitments (“pull effects”), while the EU advanced as a provider of institutional support, logistics, financial tools, and defense-industrial initiatives (“push effects”). A case study of Poland illustrates how a frontline state navigates these dynamics, using NATO’s pull and the EU’s push to expand its security agency and shape broader European defense debates. Together, these developments suggest a …

Sino-Indian Competition And Small-State Responses In The Western Indian Ocean: The Cases Of The Seychelles And Mauritius, Sidhyendra Sisodia, Manoj Kumar Mishra

Journal of Strategic Security

The India-China rivalry, once concentrated on their contested land border, has now spilled decisively into the maritime domain, with both powers competing for influence in the Indian Ocean Region (IOR). Much of the existing literature focuses on Sri Lanka and the Maldives, leaving the Seychelles and Mauritius relatively underexplored. This article addresses that gap by examining how India and China have expanded their engagement with these small island states across security, infrastructure, and political domains. Drawing on defense cooperation, infrastructure projects, and contested basing proposals, it shows that both islands adopt selective hedging, albeit in different forms. Mauritius practices asymmetrical …

Post-Ukraine Fallout: How Azerbaijan’S Break With Russia Reflects The Strategic Consequences Of A Weakened Kremlin, Hasan Alisoy

Journal of Strategic Security

This article analyzes how Russia’s declining power, accelerated by its military overextension in Ukraine, triggered a historic rupture in Russia–Azerbaijan relations, culminating in the 2025 Yekaterinburg incident. It argues that the deaths of two Azerbaijani citizens in Russian custody—and the retaliatory actions taken by Baku—did not cause the diplomatic collapse, but rather crystallized a long-term realignment rooted in Azerbaijan’s post-conflict assertiveness and Russia’s unraveling regional leverage. Drawing on the 2024 downing of an Azerbaijani airliner by a Russian missile, the premature withdrawal of Russian peacekeepers from Karabakh, and Azerbaijan’s evolving alliance with Türkiye, the article positions this realignment within a …

The Digital Radical: Online Extremism, Propagation, And Terror By Design's Strategic Implications For Homeland Security, Hunter Lacroix, Shevach Berkovits

Journal of Strategic Security

The 'lone wolf' figure has long been central to counterterrorism analysis, representing the trajectory from non-participant to self-directed actor aligned with extremist causes. Traditional frameworks emphasizing in-person networks or online exposure, however, fail to capture the transformation of radicalization in the algorithmic age. The Arab Spring demonstrated the mobilizing power of digital platforms, yet movements like ISIS later weaponized these networks to provide ideology, belonging, and identity to dislocated populations. This article introduces the concept of the Digital Radical—an individual who transitions from passive consumer to active propagator of extremist narratives, sustaining and expanding radical ecosystems in a symbiotic …

Navigating Power Play: Sri Lanka’S Strategic Role In Indo-Pacific Geopolitics, Neeraj Singh Manhas, Jyot Shikar Singh, Tilak Raj Sharma

Journal of Strategic Security

The Indo-Pacific’s geopolitical significance has surged due to China’s assertive rise, prompting the QUAD nations to counterbalance Beijing’s influence. Sri Lanka, a strategically located island state, emerges as a key hub for global trade and security. It examines how Sri Lanka navigates its geopolitical position to achieve national goals while balancing the interests of larger powers. Lastly, Colombo’s strategic engagements with major powers and regional frameworks highlight efforts to assert agency and amplify the voices of smaller island states. Despite its strategic importance, Sri Lanka’s agency is constrained by power asymmetries in the Indo-Pacific, contributing to understanding small-state geopolitics.

A Tilly Comparative Study On State-Building In South Vietnam And Afghanistan, Hoang Trung "Alex" Vu, P.S. Sam Tran

Journal of Strategic Security

The 2021 U.S. withdrawal from Afghanistan was often compared to the 1975 fall of South Vietnam as two strategic failures by the United States in attempting to establish a Western-friendly, democratic government in their regions. While superficial similarities could be observed between the two cases, this research provides a further comparative analysis of state-building efforts in South Vietnam and Afghanistan to uncover critical lessons in regime-sustaining and the politics of American intervention. The article uses Charles Tilly’s "war makes state" concept to examine war-making, state-making, protection, and extraction as core elements of state-building. The research utilizes comparative historical analysis to …

Accurate Reading Of The Result Of The Security Transfer In Vietnam, Jason Cooley

Journal of Strategic Security

In the late 1960s and early 1970s, numerous American citizens wanted to see the removal of US soldiers from South Vietnam. To appease these individuals, officials in Washington carried out troop withdrawals. As American personnel left, South Vietnamese servicemen assumed their security duties. This security transfer, like most security initiatives, produced mixed results. By employing levels of success and failure from notable policy scholars and recognizing the productivity of some key units of the South Vietnamese Army, it will be possible to present a more accurate reading of the results of the transfer than those currently available in the literature …

Sheinbaum’S Dilemma: Mexico’S Security Choices After Fto Designation, Ghaleb Krame, John P. Sullivan, Magdalena Garcia

Journal of Strategic Security

The US designation of six Mexican cartels as Foreign Terrorist Organizations (FTOs) marks a pivotal shift in bilateral security relations, compelling Mexico to navigate a complex strategic landscape. This study uses game-theoretic modeling, scenario analysis, and Nash equilibria to evaluate three possible responses by the administration of Claudia Sheinbaum: (1) Total Subordination—fully aligning with US counter-cartel efforts, (2) Covert Subordination—secretly integrating US support while maintaining a public stance of sovereignty, and (3) Strategic Resistance—rejecting US intervention in favor of an independent security approach.

New evidence on US-side border corruption and clearer definitions of key terms (joint cross-border operations, intelligence fusion …

Doctor, Teacher, Terrorist: The Life And Legacy Of Al-Qaeda Leader Ayman Al-Zawahiri. By Sajjan M. Gohel. Oxford University Press, 2023., Naveen Khan

Journal of Strategic Security

No abstract provided.

Impact Of Plasma Ptau181 Levels On Clinician Diagnostic Confidence And Management In Memory And Cognition Clinics: A Multi-Site Before-And-After Study, Johannes C. Michaelian, Azadeh Feizpour, James C. Vickers, Jane E. Alty, Jessica M. Collins, Vincent Doré, Catriona Ireland, Anna E. King, Ralph N. Martins, Michael Woodward, Sharon L. Naismith, Christopher C. Rowe

Research outputs 2022 to 2026

Introduction: Recent advances allow blood tests to detect key proteins linked to Alzheimer's disease (AD). Methods: In this before-and-after study across three Australian memory and cognition clinics, we evaluated the impact on clinicians' diagnostic confidence and management following disclosure of routine patients' AD probability, using predefined plasma phosphorylated tau 181 (pTau181) thresholds set at 90% sensitivity and 90% specificity for amyloid-beta (Aβ) positron emission tomography (PET) positivity. Results: One hundred thirteen participants (mean age: 71.2 ± 8.4; mean Mini-Mental State Examination score: 27.7 ± 2.5) with dementia (n = 17, 15.0%), mild cognitive impairment (n = 48, 42.5%), and subjective …

Setting Research Priorities For The Use Of Digital Technology In The Self-Management Of Heart Health: The Results Of The James Lind Priority Setting Partnership, Lis Neubeck, Simon Nichols, Nicola Straiton, Louise J. Dunford, Amitava Banerjee, Susan Dawkes, Donna Fitzsimons, Maria Hayes, Alistair Lawson, Abigail A. Lyons, Mary Mcauley, Jill Mclaggan, Richard Mindham, Nicholas L. Mills, Rakesh Modi, Alice Pearsons, Amanda Pitkethly, Fiona E. Strachan, Coral L. Hanson

Research outputs 2022 to 2026

Aims: There are wide inequalities in access to cardiovascular care, and risk factors such as obesity, high blood pressure, and physical inactivity are often not well managed. We aim to identify the most important questions about how digital technologies can help people and their carers prevent cardiovascular disease and improve access to care. Methods and results: A priority setting partnership that aimed to generate a top 10 list of research priorities for the use of digital technology in the prevention and management of heart disease and heart conditions in the UK and Ireland, with equal input by people with lived …

Redbird Scholar, Vol. 11, No. 2 (Spring 2026), Illinois State University, Office Of The Vice President For Research And Graduate Studies

Redbird Scholar

No abstract provided.

A Treat-To-Target Approach For Obesity Management: A Post Hoc Analysis Of The Surmount-5 Trial., Carel W Le Roux, Luca Busetto, Louis Aronne, Deborah Bade Horn, Georgios K Dimitriadis, Beverly Falcon, Luis-Emilio Garcia-Perez, Elisa Gomez Valderas, Theresa Hunter Gibble, Cagri Senyucel, Julia P Dunn

Faculty, Staff and Student Publications

Introduction: With new advancements in obesity medicine, clarity on goals and expectations for successful disease management is limited. This post hoc analysis assessed application of proposed treat-to-target (TtT) thresholds for obesity to the outcome measures of SURMOUNT-5, which randomised participants with obesity to tirzepatide or semaglutide.

Methods: The proportion of participants in each treatment group reaching proposed TtT thresholds for waist to height ratio (WHtR) < 0.53, body mass index (BMI) < 27 kg/m2, or a combination was evaluated. The associations between the thresholds and achieving low disease activity to remission (meeting goals for at least four of five defined cardiometabolic risk parameters) and normalisation or improvement in SF-36v2 physical component score (PCS) from baseline to week 72 were explored.

Results: About 23.1%-33.9% of participants treated with tirzepatide and 14.2%-20.7% treated with semaglutide reached the TtT thresholds, with greater weight reduction than the overall population. About 77% of participants who reached WHtR < 0.53 achieved low disease activity to remission, with an odds ratio of 2.31 (p < 0.001) compared to those who did not reach this target. The BMI threshold was not statistically associated with the assessed outcomes for SF-36v2 PCS.

Conclusion: In this …

Characterising Soil Microbial Communities In Thinned And Unthinned Eucalyptus Forest In Southwestern Australia, Aaron J. Brace, Laurence Dugal, Josephine Hyde, Kristen Fernandes, Anna J.M. Hopkins, Emma Stevens, Gavan S. Mcgrath, Katinka X. Ruthrof

Research outputs 2022 to 2026

Climate change stress in forested ecosystems globally has led to die-off events, and management actions are needed to help mitigate these pressures. Forest thinning has been proposed to reduce competition for moisture between trees, however, the effects of forest thinning on lesser-studied organisms, such as soil microbial communities, need quantification. Soil microbial communities are essential for processes such as nutrient cycling and can be used as indicators of below-ground health and as an overall proxy for biodiversity. This study examined soil microbial communities, and site and soil characteristics, directly at the base of trees and in inter-tree spaces in a …

Using Social Network Analysis To Visualise Place-Based Partnerships For Systems Change In Regional Australia, Stephanie L. Godrich, Isabelle Chiera, Melissa Stoneham, Jess Doe, Amanda Devine, Emily Humphreys

Research outputs 2022 to 2026

Issue Addressed: Social network analysis (SNA) is a novel approach to investigating food security systems change in regional and remote communities. With short-term, siloed food security solutions often proving ineffective, this study used SNA to visualise how organisations across a vast area in Western Australia (WA) were working in partnership to support systems change and identify where these partnerships could be strengthened. Methods: One hundred and one food security initiative leaders, representing 148 initiatives, participated in semi-structured interviews. The number and type of regional partnerships were measured, and region-based partnership network typologies determined. Results: Most regions’ partnership networks were ‘Scattered …

Zwitterionic And Anionic Ultrafiltration Membrane Modification For Efficient, Fouling-Resistant Microalgae Harvesting, Victor Okorie Mkpuma, Mohadeseh Najafi, Javad Farahbakhsh, Masoumeh Zargar, Navid Reza Moheimani, Houda Ennaceri

Research outputs 2022 to 2026

Membrane surface modification is a promising strategy for fouling mitigation in membrane-based microalgae filtration, primarily by limiting the interactions between the membrane surface and the foulant particles. This study investigated the effectiveness of modified membranes in filtering Chlorella sp. MUR 269. First, three polyethersulfone membranes with varying pore sizes were evaluated to determine the influence of pore size on filtration performance and fouling behavior. The ultrafiltration membrane that exhibited the best performance was subsequently modified using two functional monomers: the zwitterionic [2-(methacryloyloxy)ethyl]dimethyl (3-sulfopropyl) ammonium hydroxide and the negatively charged mono-2-(methacryloyloxy)ethyl succinate (MMS). The filtration performance and fouling resistance of the …

Combined Effect Of Sarcopenia And Impaired Respiratory Function On All-Cause Death: A Nationwide Cohort Study, Chutao Wu, Dan Wu, Mu Li, Senrong Lu, Yukai Wang, Yulong Lan

Research outputs 2022 to 2026

Background: Respiratory fitness and sarcopenia status have been reported to be cross-sectionally linked with each other and increase mortality risk. However, little is currently known regarding the connection between impaired respiratory function and sarcopenia and their joint effect on future death risk. Methods: This study included 12 027 participants (50.8% were women; mean [SD] age, 58.9 [9.3] years) from a nationwide, prospective cohort in China (China Health and Retirement Longitudinal Study). Respiratory function was assessed by peak expiratory flow (PEF). Sarcopenia status was assessed according to the Asian Working Group for Sarcopenia 2019 (AWGS 2019) criteria. Time-to-event survival analyses and …

Engineering Zinc Anodes Through Advanced Manufacturing Strategies For Next-Generation Zinc–Air Batteries, Yasir Arafat, Kareem Bakhsh, Muhammad Rizwan Azhar

Research outputs 2022 to 2026

Rechargeable zinc–air batteries (ZABs) are promising next-generation energy storage systems due to their high energy density, intrinsic safety, and low cost. Nevertheless, commercial deployment of Zn anodes is hampered by persistent challenges like dendrite formation, deformation, passivation, corrosion, and the hydrogen evolution reaction. This review systematically highlights the critical relationship between anode morphology and electrochemical performance and discusses recent advances in advanced manufacturing strategies for Zn anodes. Additive manufacturing approaches, such as 3D printing, enable the fabrication of porous and tunable Zn electrodes with enhanced surface area and uniform ion flux distribution. Furthermore, advanced materials processing techniques like alloying, coatings, …

Preoperative Health During A Pandemic: An Observational Study Assessing Lifestyle Changes In Patients Associated With Covid-19 In Western Australia, Nadine Radin, Dana Hince, Jim Codde, Paola Chivers, Dale W. Edgar

Research outputs 2022 to 2026

Background and Aim: Healthcare service disruptions resulting from the COVID-19 pandemic led to substantial changes in surgical pathways across public hospitals in Western Australia (WA). These disruptions, compounded by restrictions and containment measures, influenced the health and lifestyle behaviours of the WA community, including patients awaiting surgery. This study aimed to assess changes in self-reported modifiable lifestyle risk factors among patients during COVID-19. Methods: This observational study analysed hospital patient data across three seasonally matched calendar periods: Period 1 (January–March 2019 vs 2020), Period 2 (March–July 2019 vs 2020), and Period 3 (July–December 2019 vs 2020). Multivariable regression models were …

Overservice Backfires: The Impact Of High Robot Attentiveness On Tourists' Discontinuous Usage Intentions, Jinwei Wang, Yingzong Tang, Xin Chen, Songshan (Sam) Huang

Research outputs 2022 to 2026

AI-powered robots can meet both functional and emotional consumer service needs through proactive engagement. Yet, excessive attentiveness may produce unintended negative outcomes. Drawing on conservation of resources theory, this research employs four studies and a single-paper meta-analysis to investigate how highly (vs. moderately) attentive robotic service influences tourists' intentions to discontinue use. Results show that highly attentive robotic service increases discontinuous usage intentions, and this effect unfolds sequentially through perceived threat to freedom and emotional exhaustion. Furthermore, information sensitivity and technology anxiety moderate the relationship between robotic attentiveness and discontinuous usage intentions. These findings offer strategic insights for tourism practitioners …

Self-Management Challenges And Psychosocial Support Needs In Clean Intermittent Catheterization: A Qualitative Study Of Individuals With Neurogenic Bladder And Caregivers, Lianyu Zou, Xiaomei Wu, Shun Chen, Shuluan Feng, Xiaohua Huang, Weiting Liu

Research outputs 2022 to 2026

Background – Clean intermittent catheterization (CIC) is widely regarded as the preferred approach to bladder management for individuals with neurogenic bladder (NB). Nevertheless, a considerable gap persists between evidence and clinical practice: patients and caregivers frequently encounter self-management barriers that compromise clinical outcomes during CIC. This qualitative study explores these barriers to provide an empirical foundation for developing tailored strategies that improve quality of care. Design – A descriptive qualitative study. Methods – From August to October 2025, a convenience sampling method was employed to recruit 16 participants individuals with NB or their long-term caregivers from the Department of Rehabilitation …