Digital Commons Network^™

Etalanetug (E2814) In Dominantly Inherited Alzheimer's Disease: An Open-Label Phase 1b/2 Study To Assess Safety And Target Engagement In Participants With Mild To Moderate Cognitive Impairment, Erica Andreozzi, Kanta Horie, Nicolas R Barthélemy, Brian A Gordon, Shaney Flores, Tammie L S Benzinger, Eric Mcdade, Randall J Bateman, Et Al.

2020-Current year OA Pubs

INTRODUCTION: Etalanetug (E2814) is designed to delay the clinical progression of Alzheimer's disease (AD) by binding to the microtubule binding region (MTBR) of tau implicated in seeding and spreading of tau pathology. Dominantly inherited Alzheimer's disease (DIAD) is a rare form of the disease (<  1%), having similar changes in the tau distribution and pathology to sporadic AD. Herein, we report the safety, pharmacology and biomarker results of the etalanetug Study 103 in DIAD patients.

METHODS: Study 103 enrolled participants with mild-to-moderate cognitive impairment due to DIAD who received etalanetug intravenously every 4 weeks escalating from 750 mg, 1500 mg, 3000 mg, to 4500 mg. After ascending to 4500 mg, patients received 4500 mg for up to 108 weeks. Tau pathology biomarkers, ptau217 and MTBR-tau243 were measured in CSF. Additional …

Tindak Pidana Terhadap Penyelenggaraan Peradilan, Loebby Luqman, S.H, M.A.

Jurnal Hukum & Pembangunan

Abstract

Patroli Polisi Sebagai Tugas Preventive, Drs. Dpm. Sitompul, S.H, M.A.

Jurnal Hukum & Pembangunan

Abstract

Hak Asasi Manusia, Luhut M.P. Pangaribuan

Jurnal Hukum & Pembangunan

Abstract

Lingkungan Sebagai Subyek Hukum Dan Kewenangan Publik Lsm Lingkungan, Dr. Daud Silalahi, S.H.

Jurnal Hukum & Pembangunan

Abstract

Pengaruh Sistim Peradilan Pidana Terhadap Sikap Dan Cara Tindak Aparat Penegak Hukum, Rudy Satryo, S.H.

Jurnal Hukum & Pembangunan

Abstract

Genetic Secrets Unveiled: Unraveling Privacy Concerns In Direct-To- Consumer Genetic Testing Between The United States And The European Union, Sofia Marie Cabrera

Journal of International Law and Comparative Studies

No abstract provided.

A Case For Idaho And Other Western States Owning Their Own Land, Alisha Urrutia

Idaho Law Review

Idaho and other states in the western United States have struggled with federal ownership and management of public lands for decades. Since 1976, when the Federal Land Management and Policy Act was enacted and the Homestead Act was repealed, states in the west have challenged the constitutionality and legal authority of the BLM to hold onto and manage western lands in a myriad of ways. This article discusses some of the most recent challenges to this system, including a lawsuit filed by the State of Utah in August of 2024. This article expands on these challenges, citing legal and political …

Fool's Gold: The Stibnite Gold Project, Critical Minerals, And The Public Health Perils Of Antiquated Hardrock Mining Laws, Faith Quigley

Idaho Law Review

The proposed reopening of the Stibnite Gold Mine in Idaho has been heralded as a model for the future of modern hardrock mining. This project has received national interest in light of the growing domestic demand for critical minerals essential to climate-friendly energy technologies and national security. But beneath its green branding lies a deeper legal and public health crisis. Operating under the General Mining Law of 1872—a relic of frontier-era resource exploitation—the Stibnite Gold Project exemplifies how an outdated legal framework continues to enable environmental and human harm. While policymakers tout the domestic necessity of critical minerals, the Stibnite …

Facing The Accused: The Confrontation Clause And Protecting Child Victims Of Sexual Abuse, Raquel Pearson

Idaho Law Review

The Sixth Amendment’s Confrontation Clause provides individuals the right to confront witnesses testifying against them. For decades, Idaho case law has grappled with the delicate balance between protecting victims of sexual assault and upholding defendants’ rights to cross examine their accusers. This delicate balance is further exacerbated when sexual assault cases involve minors, particularly in deciding whether victim statements implicate the Confrontation Clause. The Idaho Supreme Court considers the totality of the circumstances when evaluating whether a defendant’s right to confront a witness has been violated, but the standard for when the Clause is triggered remains unclear.

This Note seeks …

From Stigma To Statute: A Historical And Legal Comparative Analysis Of Involuntary Commitment Laws In Idaho, Jessica Cambron

Idaho Law Review

A lesser-known area of law in Idaho concerns the involuntary civil commitment process, a process by which thousands of people per year are committed to hospitals around the state. These laws, specifically in Idaho, govern the criteria which must be met for a person to be placed on an involuntary hold, detained in a hospital setting awaiting proceedings, or potentially committed.

Understanding the evolution of mental illness and the role of involuntary commitment – including successes, failures, and challenges – is essential to navigating reform. This Comment provides a brief history of mental illness, including key cultural events and cases …

Preserving Rural School Districts From The Threat Of Vouchers And Charters, Preston C. Green Iii

Idaho Law Review

School vouchers and charter schools are primed to grow at a time when public school systems are experiencing a precipitous decline in enrollment. Unfortunately, for many rural school districts, this challenging environment may endanger their very existence, to the detriment of the students and the communities they serve. To guard against this potential harm, this article calls for state legislatures to designate certain classes of rural districts as “education preserves.” This article also explains how states can create education preserves in a manner that can withstand Free Exercise Clause challenges.

Engineered For Surveillance: Public Safety, Roadway Science, And The Fourth Amendment, Trayce Hockstad, Steven Jones

Idaho Law Review

No abstract provided.

Invisible In The Storm: Disasters And The Disability Divide, Helia Hull

Idaho Law Review

“Sometimes it takes a natural disaster to reveal a social disaster.”

From Vision To Impact: Building A Sustainable Open-Access Peer Reviewed Medical Journal, Darshana T. Shah Phd

All Things Open

The Marshall Journal of Medicine (MJM) was created to strengthen scholarly exchange, clinical innovation, and health professions education in rural Appalachia while making that work openly accessible to readers worldwide. As West Virginia’s first fully open‑access, online, peer‑reviewed medical journal, MJM illustrates how a mission‑driven publishing effort can evolve from an initial idea into lasting scholarly infrastructure—and how publication activity can translate into measurable impact.

MJM’s development centered on three strategic pillars:

• a clearly articulated scope focused on clinically relevant and educationally innovative scholarship
• rigorous peer‑review and editorial practices that ensure credibility and quality
• operational partnerships—especially with academic …

From Imposter To Expert: Building Students Confidence And Professional Identity, Megan E. Rodgers

Research Days

Goal of the session: This workshop transforms how graduate students experience imposter syndrome by providing evidence-based strategies for building authentic confidence and professional identity. Rather than simply normalizing imposter feelings, participants learn to recognize cognitive distortions, document their expertise development, and construct professional identities rooted in genuine competence. By session's end, participants will have concrete tools for challenging self-doubt in real-time and a foundational professional identity statement reflecting their unique strengths and values. Topics covered: Three core areas are addressed: the psychological mechanisms of imposter syndrome, including the imposter cycle and cognitive distortions such as all-or-nothing thinking; evidence-based confidence building …

The Future Is Diamond: Open Journals Collective, Galadriel Chilton, Caroline Edwards

All Things Open

The Open Journals Collective is a Collective Community Interest Company based in the UK that exists to benefit the community rather than private shareholders. Composed of journal publishers, editors, and librarians, the OJC community is dedicated to building a sustainable future for academic journals as a strong alternative to profit-making models of global corporate publishing and data systems. Officially launched in January 2026, this international organization is working to build a scalable pathway away from commercial publishers and subscription models to keep academic publishing within values-aligned organizations. But what is diamond open access, and why is it important for libraries …

Examining The Benefits Of A Standardized Protocol For Hyperglycemia Screening In Adult Oncology Patients: A Pilot Study, Alexa Dashko

Pacific Journal of Health

Many individuals receiving cancer directed therapy are at risk of developing hyperglycemia and new, or worsening of, diabetes due to location of their cancer, treatment regimen, and/or prolonged use of steroids. Research shows that uncontrolled hyperglycemia can have detrimental effects on individuals’ response to cancer therapy, treatment associated toxicities, quality of life and overall mortality. Despite extensive research identifying the need for routine monitoring and management of hyperglycemia in oncology patients, medical societies have yet to establish formal screening guidelines for practitioners. The aim of this pilot study was to examine the outcomes of establishing a protocol for screening and …

Humanizing Engineering For Preservice Elementary Teachers Through Sustainable Engineering Stories, Jeffrey D. Radloff, Madison M. Morris, Jacob Pleasants

Journal of Pre-College Engineering Education Research (J-PEER)

Meeting the goals of US K–12 science education reform requires that preservice elementary teachers (PSTs) understand engineering as a specialized discipline and a human endeavor that addresses real-world issues. Yet in their formal education, few PSTs receive opportunities to learn about the humanistic dimensions of engineering: engineers’ personal values and motivations, the sociocultural nature of engineering work, and the societal significance of engineering. Storytelling about engineering offers a practical way to give PSTs access to these ideas. This study examines the impacts of integrating storytelling about engineering in a science methods course for future elementary school teachers. Over a two-year …

How Journal Editors Are Addressing Challenges With No-Fee Open Access, Colleen Lyon, Christopher Hollister

All Things Open

No-fee or “diamond” open access embodies the principles of the UNESCO Recommendation on Open Science, particularly openness, inclusivity, and collaboration. This model of publishing strengthens equitable access to knowledge, promotes multilingualism, and democratizes science.

Unique among open access models, no-fee open access eliminates both APCs and subscription fees, making it completely free for both authors and readers. This model is often funded by academic institutions, governments, or non-profit organizations, focusing on equity, inclusivity, and accessibility.

To investigate the efficacy of this model, the presenters administered a survey of North American no-fee journal editors to explore the challenges of managing no-fee …

Greenaissance? Zero-Embargo Funder Mandates And Green Open Access, Josh Cromwell

All Things Open

Recently, several funder-driven Open Access mandates, such as Plan S in Europe or the NIH Public Access Policy in the US, have indicated a desire to shift away from allocating funds for article processing charges (APCs) and have instead called for significantly reducing or eliminating embargo periods on accepted manuscripts (AMs) to make them a viable pathway to compliance for researchers.

This talk will address how these policies can significantly revitalize Green Open Access and open repositories, and will discuss strategies for researchers and librarians to use these new policy changes as an opportunity to share their research openly without …

Proxyconnec: A Lora-Based Proactive Safety Communication System For Off-Grid Environments, Shruti Bhandari, Roza Shaimurat

ATU Scholars Symposium

Remote environments lacking cellular or satellite coverage present significant safety challenges. ProxyConnec was developed as a point-to-point communication system using ESP32 microcontrollers and REYAX RYLR998 LoRa modules to provide off-grid monitoring.

The system implements a proactive heartbeat model in which a beacon device transmits a signal every 1,000 milliseconds. A base station monitors this connection using a 5,000 millisecond watchdog timer. If communication is interrupted, the system immediately triggers audible and visual alerts. Unlike conventional tracking devices that depend on manual SOS activation, this design treats unexpected signal loss as a potential safety event.

The manufacturer rates the selected LoRa …

A Comprehensive Survey Of Agentic Ai: Design Principles, Security Risks, And Ethical Consideration, Md Shaba Sayeed

ATU Scholars Symposium

In the past several years, the world has managed to transition away from simple automation to independent AI systems. Agentic AI is an agent that can work independently, carrying out all essential plans and implementations without any kind of supervision from a human being. This review has tried to demonstrate the transformative impact that Agentic AI brings to contemporary models of intelligence by means of synthesis of perception, reasoning, and goal. We utilized the phrases Agentic AI, autonomous AI, multi agent systems as keywords in Google Scholar, ScienceDirect, arXiv, and other digital libraries. We have used these 38 main papers …

Honors In Focus: A Study Of Public University Programs With New Course Proposals For Arkansas Tech University, Haley Greer, Payton Mccain, Hannah Melton

ATU Scholars Symposium

This project evaluates the structure and effectiveness of honors programs at Arkansas Tech University and five comparable public institutions—University of Central Arkansas, Arkansas State University, Truman State University, Northeastern State University, and the University of Central Missouri—to identify best practices that support student achievement, engagement, and retention. The study was designed to assess how honors programs influence academic rigor, curricular flexibility, community development, and access to high-impact educational opportunities. Using a mixed-methods approach, the researchers collected data through student and faculty surveys, follow-up interviews, and a comparative review of institutional materials, including honors curricula, housing models, scholarship structures, and program …

Creating A Floating Volumetric Display, Joy Skaggs, Hope Skinner

ATU Scholars Symposium

The public has long been interested in futuristic technology, especially ‘holograms’ and their possibilities, evidenced by pop culture icons such as Iron Man and the popularity of the Sci-Fi Genre. The popular term ‘hologram’ actually describes the phenomenon of a volumetric display, where light is directed to form 3D forms in the air. Attempts to create these volumetric displays began as early as 1988 with creators like Gregg Favelora and Alan Sullivan. As technology improved, so too did the ability to make the futuristic ‘hologram’ a reality.

Another common form of these interactive holograms is the floating display, which may …

Investigating The Effect Of Kcl Stress In Raphanus Sativus, Mason P. Oelke

ATU Scholars Symposium

Presented by Stephanie Nelms at the Arkansas INBRE Conference on November 7-8, 2025.

Presented by Mason Oelke at Arkansas Tech Scholar's Symposium on April 9th, 2026.

Potassium is an essential macronutrient for plant growth and development, yet excessive potassium fertilization can induce salt stress with detrimental consequences for crop productivity and nutritional quality. Despite its agricultural relevance, potassium chloride induced stress remains significantly understudied compared to classical sodium-based salinity. This thesis investigates the physiological, biochemical, and molecular responses of Raphanus sativus to KCl stress using an integrated approach that combines germination assays, mineral profiling, and gene expression analysis.

Radish seeds …

Weathering The Storm Online: Risk Communication During The 2026 Arkansas Winter Storm, Latifat A. Sodiya, Takiya Hutchinson

ATU Scholars Symposium

In January 2026, Arkansas experienced a severe winter storm that resulted in extreme low temperatures, ice-covered roads, and social disruption of daily routine of Arkansans. In the Arkansas River Valley, the storm led to the closure of businesses and schools for several days. This study concentrates on risk communication during the 2026 Arkansas Winter Storm and examines how social media was utilized by county emergency management agencies to disseminate risk information during the event. The data for the study was collected from official Facebook accounts of county emergency management agencies for a seven day period (January 21 - 27, 2026) …

Grassland Bird Community Responses To Fire Management, Mason H. Dillard

ATU Scholars Symposium

Vegetation structure plays a major role in determining avian community makeup. Controlled burn frequency changes vegetation structure and consequently the makeup of avian communities. To examine this relationship, I surveyed breeding birds in grasslands and savannahs of the Ozark Mountains, Arkansas River Valley, and Northwest Arkansas. I created models to outline the relationship between these three factors (avian community, fire management, and vegetation structure.) I also examined surrounding land cover and patch size as potential variables that may impact avian community structures.

I will outline the role fire management plays in determining the makeup of breeding bird communities in grasslands, …

Proactive Mental Health Assistance Via Agentic Llm Chatbots With Retrieval-Augmented Generation, Shaira Wajiha

ATU Scholars Symposium

Mental health challenges such as anxiety and depression are widespread, yet often remain unaddressed due to stigma, financial barriers, limited access to professionals, or personal reluctance. To address this gap, we present an accessible AI-powered chatbot that provides preliminary conversational support with empathetic, context-aware responses. The chatbot is trained and evaluated on two publicly available counseling conversation datasets from Huggingface, enabling it to learn and maintain therapeutic dialogue patterns. We compare three advanced LLMs, such as Llama3.1, Mistral 7b, and Qwen3, evaluating them on relevance, empathy, conciseness, and contextual understanding, and all models demonstrate high response quality. Incorporation of a …

Out Of Alignment: Grant Administrator And Principal Investigator Views On Internal Grant Success, Impact, And Roi, Stephanie Mccombs, Matt Karpov, Miasha T. O'Neal

Research Development Review: The NORDP Journal

This study aimed to define, evaluate, and standardize the concepts of success, impact, and return on investment (ROI) in the context of internal grant administration. Understanding these elements is crucial for institutions aiming to maximize the value derived from internal funding. This preliminary research study explored the varying definitions of success, impact, and ROI across institutions, recognizing disparities between Grant Administrator and investigator perspectives. Survey questions were designed to investigate these definitions and assess current practices. Participants included 117 Grant Administrators (GAs) and Principal Investigators (PIs) at various institutions, recruited through the NORDP network. The study utilized a mixed-methods approach, …