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Nyls Earns Top Marks In Prelaw Magazine’S Spring 2023 Issue, Julia Sonenshein Jun 2023

Nyls Earns Top Marks In Prelaw Magazine’S Spring 2023 Issue, Julia Sonenshein

NYLS Community News

No abstract provided.

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Red Breast Syndrome And Acellular Dermal Matrix, Allison Podsednik Gardner, Aidee Nunez, Mauricio De La Garza Jun 2023

Red Breast Syndrome And Acellular Dermal Matrix, Allison Podsednik Gardner, Aidee Nunez, Mauricio De La Garza

School of Medicine Publications

Increasingly popular for use in breast reconstruction, acellular dermal matrix (ADM) can provide support and protection to implants. However, use of ADM may be associated with infection and complications, including red breast syndrome (RBS). RBS is an inflammatory event that typically presents with cutaneous erythema over the domain where the ADM is surgically implanted. As ADM use increases, presumably, more cases of RBS will occur. Thus, techniques and tools to mitigate or manage RBS are needed to improve patient outcomes. Here, we describe a case where RBS was diagnosed and interestingly resolved after exchange for a different brand of dermal …

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Single Cell Clonotypic And Transcriptional Evolution Of Multiple Myeloma Precursor Disease, Minghao Dang, Ruiping Wang, Hans C Lee, Krina K Patel, Melody R Becnel, Guangchun Han, Sheeba K Thomas, Dapeng Hao, Yanshuo Chu, Donna M Weber, Pei Lin, Zuzana Lutter-Berka, David A Berrios Nolasco, Mei Huang, Hima Bansal, Xingzhi Song, Jianhua Zhang, Andrew Futreal, Luz Yurany Moreno Rueda, David E Symer, Michael R Green, Cristhiam M Rojas Hernandez, Michael Kroll, Vahid Afshar-Khargan, Libere J Ndacayisaba, Peter Kuhn, Sattva S Neelapu, Robert Z Orlowski, Linghua Wang, Elisabet E Manasanch Jun 2023

Single Cell Clonotypic And Transcriptional Evolution Of Multiple Myeloma Precursor Disease, Minghao Dang, Ruiping Wang, Hans C Lee, Krina K Patel, Melody R Becnel, Guangchun Han, Sheeba K Thomas, Dapeng Hao, Yanshuo Chu, Donna M Weber, Pei Lin, Zuzana Lutter-Berka, David A Berrios Nolasco, Mei Huang, Hima Bansal, Xingzhi Song, Jianhua Zhang, Andrew Futreal, Luz Yurany Moreno Rueda, David E Symer, Michael R Green, Cristhiam M Rojas Hernandez, Michael Kroll, Vahid Afshar-Khargan, Libere J Ndacayisaba, Peter Kuhn, Sattva S Neelapu, Robert Z Orlowski, Linghua Wang, Elisabet E Manasanch

Faculty, Staff and Student Publications

Multiple myeloma remains an incurable disease, and the cellular and molecular evolution from precursor conditions, including monoclonal gammopathy of undetermined significance and smoldering multiple myeloma, is incompletely understood. Here, we combine single-cell RNA and B cell receptor sequencing from fifty-two patients with myeloma precursors in comparison with myeloma and normal donors. Our comprehensive analysis reveals early genomic drivers of malignant transformation, distinct transcriptional features, and divergent clonal expansion in hyperdiploid versus non-hyperdiploid samples. Additionally, we observe intra-patient heterogeneity with potential therapeutic implications and identify distinct patterns of evolution from myeloma precursor disease to myeloma. We also demonstrate distinctive characteristics of …

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Strengthening The Choice For A Generic Qualitative Research Design, Jeri L. Ellis Edd, David L. Hart Phd Jun 2023

Strengthening The Choice For A Generic Qualitative Research Design, Jeri L. Ellis Edd, David L. Hart Phd

The Qualitative Report

Supporting the choice for research using a generic qualitative design is needed to assist the researchers with helpful guidance and descriptions about the approach in research. The name “generic” can be rather obtuse. Determining its appropriateness goes beyond discussions about combining elements of other traditional qualitative designs and considers the generic approach as a standalone methodology. Despite its inherent flexibility, the strength of the generic design offers a view of descriptive research data for interpretation that includes personal meaning making in research and is particularly well suited for counseling and other social sciences. The strengths, benefits, and limitations of the …

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Clinical Significance And Biology Of Circulating Tumor Dna In High-Risk Early-Stage Her2-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy, Mark Jesus M Magbanua, Lamorna Brown Swigart, Ziad Ahmed, Rosalyn W Sayaman, Derrick Renner, Ekaterina Kalashnikova, Gillian L Hirst, Christina Yau, Denise M Wolf, Wen Li, Amy L Delson, Smita Asare, Minetta C Liu, Kathy Albain, A Jo Chien, Andres Forero-Torres, Claudine Isaacs, Rita Nanda, Debu Tripathy, Angel Rodriguez, Himanshu Sethi, Alexey Aleshin, Matthew Rabinowitz, Jane Perlmutter, W Fraser Symmans, Douglas Yee, Nola M Hylton, Laura J Esserman, Angela M Demichele, Hope S Rugo, Laura J Van 'T Veer Jun 2023

Clinical Significance And Biology Of Circulating Tumor Dna In High-Risk Early-Stage Her2-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy, Mark Jesus M Magbanua, Lamorna Brown Swigart, Ziad Ahmed, Rosalyn W Sayaman, Derrick Renner, Ekaterina Kalashnikova, Gillian L Hirst, Christina Yau, Denise M Wolf, Wen Li, Amy L Delson, Smita Asare, Minetta C Liu, Kathy Albain, A Jo Chien, Andres Forero-Torres, Claudine Isaacs, Rita Nanda, Debu Tripathy, Angel Rodriguez, Himanshu Sethi, Alexey Aleshin, Matthew Rabinowitz, Jane Perlmutter, W Fraser Symmans, Douglas Yee, Nola M Hylton, Laura J Esserman, Angela M Demichele, Hope S Rugo, Laura J Van 'T Veer

Faculty, Staff and Student Publications

Circulating tumor DNA (ctDNA) analysis may improve early-stage breast cancer treatment via non-invasive tumor burden assessment. To investigate subtype-specific differences in the clinical significance and biology of ctDNA shedding, we perform serial personalized ctDNA analysis in hormone receptor (HR)-positive/HER2-negative breast cancer and triple-negative breast cancer (TNBC) patients receiving neoadjuvant chemotherapy (NAC) in the I-SPY2 trial. ctDNA positivity rates before, during, and after NAC are higher in TNBC than in HR-positive/HER2-negative breast cancer patients. Early clearance of ctDNA 3 weeks after treatment initiation predicts a favorable response to NAC in TNBC only. Whereas ctDNA positivity associates with reduced distant recurrence-free survival …

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Leveraging Mid-Infrared Spectroscopic Imaging And Deep Learning For Tissue Subtype Classification In Ovarian Cancer, Chalapathi Charan Gajjela, Matthew Brun, Rupali Mankar, Sara Corvigno, Noah Kennedy, Yanping Zhong, Jinsong Liu, Anil K Sood, David Mayerich, Sebastian Berisha, Rohith Reddy Jun 2023

Leveraging Mid-Infrared Spectroscopic Imaging And Deep Learning For Tissue Subtype Classification In Ovarian Cancer, Chalapathi Charan Gajjela, Matthew Brun, Rupali Mankar, Sara Corvigno, Noah Kennedy, Yanping Zhong, Jinsong Liu, Anil K Sood, David Mayerich, Sebastian Berisha, Rohith Reddy

Faculty, Staff and Student Publications

Mid-infrared spectroscopic imaging (MIRSI) is an emerging class of label-free techniques being leveraged for digital histopathology. Modern histopathologic identification of ovarian cancer involves tissue staining followed by morphological pattern recognition. This process is time-consuming and subjective and requires extensive expertise. This paper presents the first label-free, quantitative, and automated histological recognition of ovarian tissue subtypes using a new MIRSI technique. This optical photothermal infrared (O-PTIR) imaging technique provides a 10× enhancement in spatial resolution relative to prior instruments. It enables sub-cellular spectroscopic investigation of tissue at biochemically important fingerprint wavelengths. We demonstrate that the enhanced resolution of sub-cellular features, combined …

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Prospective Applicability Of Section 34 Under The Arbitration Amendment Act, 2015, D. Gracious Timothy Jun 2023

Prospective Applicability Of Section 34 Under The Arbitration Amendment Act, 2015, D. Gracious Timothy

National Law School Business Law Review

No abstract provided.

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Arbitration And Conciliation (Amendment) Act, 2015: Arbitrators And Conflict Of Interest, Professor Anurag K. Agarwal Jun 2023

Arbitration And Conciliation (Amendment) Act, 2015: Arbitrators And Conflict Of Interest, Professor Anurag K. Agarwal

National Law School Business Law Review

No abstract provided.

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The Indian Equalisation Levy: Inelegant But Not Unexpected, Shreya Rao Jun 2023

The Indian Equalisation Levy: Inelegant But Not Unexpected, Shreya Rao

National Law School Business Law Review

No abstract provided.

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Who Will Watch The Watchmen? – A Study Of The Law On Self-Dealing Transactions By Company Directors, Vanshaj Jain Jun 2023

Who Will Watch The Watchmen? – A Study Of The Law On Self-Dealing Transactions By Company Directors, Vanshaj Jain

National Law School Business Law Review

No abstract provided.

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Critique Of The Insolvency & Bankruptcy Code, 2016, Pramod Rao Jun 2023

Critique Of The Insolvency & Bankruptcy Code, 2016, Pramod Rao

National Law School Business Law Review

No abstract provided.

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First Report Of Regeneration In The Genus Mesobuthus (Scorpiones: Buthidae), Rıdvan Kurt, Ersen A. Yağmur, Gülhanım Çelik Jun 2023

First Report Of Regeneration In The Genus Mesobuthus (Scorpiones: Buthidae), Rıdvan Kurt, Ersen A. Yağmur, Gülhanım Çelik

Euscorpius

A new example of scorpion leg regeneration is reported in an adult male Mesobuthus mesopotamicus (Penther, 1912). A claw (pretarsus) was observed to regenerate at the distal end of the tibia of the left leg II. The regeneration case is described and illustrated.

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Significance Of Academic Libraries In Recent Times: A Review Of Articles, George Noble Hotsonyame Jun 2023

Significance Of Academic Libraries In Recent Times: A Review Of Articles, George Noble Hotsonyame

Library Philosophy and Practice (e-journal)

The evolution of information communication technology tools has caused unprecedented change in the information seeking behavior of library users to the extent that the relevance of academic libraries in the 21st century is often being questioned. Consequently, academic libraries are trying their best to innovate and find innovative solutions to keep abreast with the changing needs of library users. This review seeks to provide understanding of the changing roles of the 21st century academic library. It also considered the studies done on the key paradigms, major changing roles of the academic libraries, recent technologies in the library and …

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The Provisions Of The Option Of The Condition In Jurisprudence And Its Impact On Dealers أحكام خيار الشرط في الفقه وأثره بين المتعاملين, Somayya Ahmad Freijat Jun 2023

The Provisions Of The Option Of The Condition In Jurisprudence And Its Impact On Dealers أحكام خيار الشرط في الفقه وأثره بين المتعاملين, Somayya Ahmad Freijat

Jordan Journal of Islamic Studies

This research aims to clarify the choice of condition provisions in order to show the extent of using those jurisprudential provisions acheived the commercial dealers satisfaction. The researcher used inductive approach, and jurisprudential comparative approach between jurists' doctrines. This research gives an imprtant result that the condition of choice is the most important condition between dealer, because it acheives the complete satisfaction sharia has recommended in commercial dealings in order to gain blessing in commerce, and unfortunately, by looking at dealing between people nowadays, the researcher notice that this condition is not common, which means jurists should study provosions of …

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Why Not Be Free: The Black Worldmaking Praxis, Research Method, & Manifesto For Developing Music Interventions Against Stress In Black Youth, Armond Epps Dorsey Jun 2023

Why Not Be Free: The Black Worldmaking Praxis, Research Method, & Manifesto For Developing Music Interventions Against Stress In Black Youth, Armond Epps Dorsey

Dartmouth College Master’s Theses

Why Not Be Free? is an interdisciplinary exploration of music intervention development demonstrating the application of my integrated research and artistic practices through an outlined antiracist method for designing music to reduce stress in Black college youth and a manifesto detailing the compositional process. I draw from Black feminist and womanist thought, music cognition, and public health literature to outline a framework for designing music interventions to reduce stress among Black populations: the Music Medicine Critical Race Praxis. I situate my work among Black speculative artists reimagining experiences in everyday Black life as well as music intervention researchers integrating …

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/////// Babaamiwizh – Blood Memory And How We Carry Ancestral Histories /////// On Memory, Immersive Theatre, Improvisation, & Absurdity, Olivia Shortt Jun 2023

/////// Babaamiwizh – Blood Memory And How We Carry Ancestral Histories /////// On Memory, Immersive Theatre, Improvisation, & Absurdity, Olivia Shortt

Dartmouth College Master’s Theses

babaamiwizh – blood memory and how we carry intergenerational histories: a collection of fragmented stories and thoughts on making Indigenous art. These writings attempt to find the balance of an artist's humanity, the artistic process and working with colonial institutions. I am stitching together my perspective on Indigeneity, museums and the process of repatriation, collaboration with trusted community members, as well as the land and its medicines.

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Posttreatment Lyme Disease Syndrome And Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Systematic Review And Comparison Of Pathogenesis, Natalie Bai, Christie Richardson Jun 2023

Posttreatment Lyme Disease Syndrome And Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Systematic Review And Comparison Of Pathogenesis, Natalie Bai, Christie Richardson

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Lyme disease is the most common vector-borne illness in the United States and has been causing significant morbidity since its discovery in 1977. It is well-documented that about 10% of patients properly treated with antibiotics never fully recover, but instead go on to develop a chronic illness dubbed, posttreatment Lyme disease syndrome (PTLDS) characterized by severe fatigue, cognitive slowing, chronic pain, and sleep difficulties. This review includes 18 studies that detail the symptoms of patients with PTLDS and uses qualitative analysis to compare them to myalgic encephalitis/chronic fatigue syndrome (ME/CFS), a strikingly similar syndrome. In the majority of the PTLDS …

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The Elements Of Access: Designing Equitable Public Transit To National Forests, Abigail L. Johnson Jun 2023

The Elements Of Access: Designing Equitable Public Transit To National Forests, Abigail L. Johnson

Quantitative Social Science Undergraduate Senior Theses

This paper asks what factors make a transportation system to a national forest appealing and accessible for people of color, Hispanic and Latino people, and people of a lower socioeconomic status. I use a conjoint analysis survey experiment to measure the favorability of transit-system attributes and compare favorability between local parks and Coconino National Forest as well as between racial, ethnic, and socioeconomic groups. The findings of the study indicate no significant difference between preferences for traveling to a local park versus Coconino National Forest. This study does find that potential transit users favor a no-cost transit option over having …

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Genetic Technologies: Patent Protections & The Case For Technology Transfer, Smitha Gundavajhala Jun 2023

Genetic Technologies: Patent Protections & The Case For Technology Transfer, Smitha Gundavajhala

Washington Journal of Law, Technology & Arts

Genetic technologies range in scope from agricultural to medical applications. Most recently, during the COVID-19 pandemic, companies like Moderna developed and patented genetic technologies for diagnostic and therapeutic purposes, like the mRNA vaccine. However, patent protection provides these companies with a monopoly that ultimately limits domestic production of generic versions, thus limiting access to life-saving diagnostics and therapeutics. When a company located in one country files a patent for recognition in another country, it effectively places a hold on production of any technologies covered by that patent’s reach, whether that patent is enforced or not. However, the TRIPS Agreement, the …

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Telemedicine In The Post-Pandemic Era: Navigating Challenges For Sustainable Adoption And Future Growth, Connor Perlin, Jeffrey Y. Wang Jun 2023

Telemedicine In The Post-Pandemic Era: Navigating Challenges For Sustainable Adoption And Future Growth, Connor Perlin, Jeffrey Y. Wang

URGENT Matters

No abstract provided.

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Critical Geopolitics And The Created Worlds Of Post-9/11 Spy Film, Caitlin Anne Mccarthy Jun 2023

Critical Geopolitics And The Created Worlds Of Post-9/11 Spy Film, Caitlin Anne Mccarthy

Geography Undergraduate Senior Theses

Critical geopolitics seeks to understand how we view the world, and popular film can be a key source in unveiling common fears and hopes of a particular time. in this thesis, I explore the portrayal of the world world and themes in 21st century spy film franchises to understand what worldviews are being reinforced and created through these films. Using the terrorist attacks on September 11, 2001, as my chief historical event of influence, I analyze spy films in the James Bond and Mission: Impossible film franchises to get a sense of how these films reflected and reproduced the popular …

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Lawrence University One Hundred Seventy-Fourth Commencement, Sunday, June 11, 2023, Lawrence University Jun 2023

Lawrence University One Hundred Seventy-Fourth Commencement, Sunday, June 11, 2023, Lawrence University

Commencement Programs

No abstract provided.

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Toward A Canadian Right To Repair: Opportunities And Challenges, Anthony D. Rosborough Jun 2023

Toward A Canadian Right To Repair: Opportunities And Challenges, Anthony D. Rosborough

Articles, Book Chapters, & Popular Press

This Article draws a picture of the past, present, and future of the right to repair in Canada. It looks to early successes toward automotive right to repair, challenges faced in proposing consumer protection reforms in Ontario and Quebec, and the utility of a proposed copyright “Technological Protection Measure (TPM) exception” allowing circumvention for repair purposes. In light of right to repair priorities identified by Canada’s current federal government, the Article identifies a selection of reforms that could achieve these goals. Such reforms include creating regulations under the Copyright Act governing the use and implementation of TPMs, passing an exception …

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Undoing Of The Carceral School System In The South Bay, California, Lizet Garcia Jun 2023

Undoing Of The Carceral School System In The South Bay, California, Lizet Garcia

Geography Undergraduate Senior Theses

The school-to-prison pipeline disproportionately impacts Black and Brown low-income students. The pipeline, a well-researched phenomenon, explores the criminalization of non-white students from low-income backgrounds through surveillance and outsized disciplinary actions at their schools. Current research reveals that this disciplinary system has: not improved campus safety, cost taxpayers $35 billion annually, disrupted students' academic performance, and increased students’ lifelong experience with violence (Selvaggi, 2016). However, existing research fails to consider alternative and new systems prioritizing students' well-being and future success. My research bridges this gap by focusing on South Bay schools and communities in Los Angeles –a site currently lacking scholarship. …

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The Dilemma Of Disclosure: Designing Interpersonal Informatics Tools For Mood Tracking, Daniel Earl Westphal Jun 2023

The Dilemma Of Disclosure: Designing Interpersonal Informatics Tools For Mood Tracking, Daniel Earl Westphal

Computer Science Senior Theses

Mental health is a serious issue that affects people of all ages, but is especially prevalent amongst college age youth. In the 2020-2021 school year, researchers found that around 60% of college students met the criteria for at least one mental health condition, such as major depression or generalized anxiety disorder. Many digital interventions have been innovated in order to help address this issue. These range in type and functionality from teletherapy to medication tracking applications. Some of these digital interventions include social features that allow users to interact with other users, friends, family, or doctors; however, having social features …

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What You Don’T Know Will Hurt You: Fighting The Privacy Paradox By Designing For Privacy And Enforcing Protective Technology, Perla Khattar Jun 2023

What You Don’T Know Will Hurt You: Fighting The Privacy Paradox By Designing For Privacy And Enforcing Protective Technology, Perla Khattar

Washington Journal of Law, Technology & Arts

The persistence of the privacy paradox is proof that current industry regulation is insufficient to protect consumer’s privacy. Although consumer choice is essential, we argue that it should not be the main pillar of modern data privacy legislation. This article argues that legislation should aim to protect consumer’s personal data in the first place, while also giving internet users the choice to opt-in to the processing of their information. Ideally, privacy by design principles would be mandated by law, making privacy an essential component of the architecture of every tech-product and service.

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Consensus’S Consolidation Conundrum, James J. Bernstein Jun 2023

Consensus’S Consolidation Conundrum, James J. Bernstein

Washington Journal of Law, Technology & Arts

In Part I, this piece will highlight the history, basis, and justifications for blockchain systems over the present version of the internet. This section helps to frame where consensus mechanisms may undermine Web3’s core premise. Part II will describe the fundamentals of consensus mechanisms. Thereafter, in Part III this piece will demonstrate the pitfalls of each system - and why proof of stake is not necessarily better at fighting off some of the risks associated with consensus mechanisms. Finally, in Part IV this article offers an architectural solution: introducing a series of new protocols which would increase the cost of …

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“Tiktok Told Me I Have Adhd”: Regulatory Outlook For The Telehealth Revolution, Kaitlin Campanini Jun 2023

“Tiktok Told Me I Have Adhd”: Regulatory Outlook For The Telehealth Revolution, Kaitlin Campanini

Washington Journal of Law, Technology & Arts

Telehealth’s expansion during the COVID-19 pandemic has drastically changed the approach to healthcare in the United States. This is particularly true in the behavioral health sector where several behavioral telehealth companies have emerged to treat Attention-Deficit/Hyperactivity Disorder (“ADHD”). These companies utilize a direct-to-consumer (“DTC”) model with a virtual platform that connects subscribing patients to medical providers who can treat them for ADHD. Although this telemedicine model emphasizes convenience and efficiency, the reality is that those benefits come at the cost of patient care. The federal regulations promulgated in the Ryan Haight Online Pharmacy Consumer Protection Act of 2008 to curtail …

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Examining Disparities In Care Utilization For Early-Stage Lung Cancer Patients: An Analysis Of Patient And Physician Network Characteristics, You-Chi Liu Jun 2023

Examining Disparities In Care Utilization For Early-Stage Lung Cancer Patients: An Analysis Of Patient And Physician Network Characteristics, You-Chi Liu

Quantitative Social Science Undergraduate Senior Theses

No abstract provided.

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Examining How Unauthorized Asylum Seekers And Legal Immigrants Shape Canadian Welfare And Immigration Attitudes, Henry S. Jin Jun 2023

Examining How Unauthorized Asylum Seekers And Legal Immigrants Shape Canadian Welfare And Immigration Attitudes, Henry S. Jin

Quantitative Social Science Undergraduate Senior Theses

How will Canadian attitudes on welfare and immigration shift in response to the recent surge in irregular border crossings? Do unauthorized asylum seekers pose a greater threat to public support for immigration and welfare policies compared to legal immigrants? At a time when irregular border crossings make national headlines, the Canadian government has simultaneously announced plans to welcome record numbers of legal immigrants. This study builds upon the existing body of literature on "Canadian exceptionalism" in public support for immigration and welfare. It investigates the extent to which these positive attitudes can be maintained in the context of increasing numbers …

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