Digital Commons Network^™

Sedation And Analgesia For Reduction Of Pediatric Ileocolic Intussusception, Naveen Poonai, Daniel M Cohen, Doug Macdowell, Rakesh D Mistry, Santiago Mintegi, Simon Craig, Damian Roland, Michael Miller, Itai Shavit, Paediatric Emergency Research Networks (Pern) Paint Study Group;, Yvette Wang, Alan Nager, Theodore Heyming, Rebekah Burns, Indi Trehan, Matthew Lipshaw, Carmen Sulton, Joyce Li, Aderonke Ojo, Susan Kelly, Matthew Thornton, Kerry Caperell, Iluonose Amoni, Anna Abrams, Myto Duong, Muhammad Wassem, Adrienne Davis, Jocelyn Gravel, Evelyne Doyon Trottier, Neta Bar Am, Graham Thompson, Vikram Sabhaney, Garth Meckler, Rini Jain, Samina Ali, Silvia Bressan, Tiziana Zangardi, Giovanna Villa, Martina Giacalone, Michelle Seiler, Cyril Sahyoun, Fabrizio Romano, Zsolt Bognar, Szofia Hajosi-Kalcakosz, Lisa Amir, Said Hachimi-Idrissi, Zanda Pucuka, Astra Zviedre, Emilija Zeltina, Natalie Phillips, Meredith Borland, Sharon O'Brien, Jeanette Marchant, Amit Kochar, Shane George, Victoria Pennington, Mark Lyttle, Jen Browning, Anna Mcloughlin, Stuart Hartshorn, Chaman Urooj, Lucy Johnston, Emily Walton, Deepika Subrahmanyam Puthucode, Phil Peacock, James Conroy, Rafael Marañon, Silvia Garcia, Nuria Cahís, Amaia Cámara-Otegui, Arantxa Gomez, Maria Carbonero, Carlos Angelats-Romero, Adriana Yock-Corrales, Gabriela Hualde, Fabian Spigariol, Alex Donas, Cinthia Gübeli Linné, Alessia Rocchi, Alessia Pedrazzini, Giorgio Cozzi, Dino Barbi, Laura Baggio, Giovana La Fauci, Angela Mauro, Matthew Steimle, Danilo Buonsenso, Irma Ugalde, Gaby Nieva, Charlotte Harper, Idanna Sforzi, Shobhit Jain

Faculty, Staff and Student Publications

IMPORTANCE: Ileocolic intussusception is an important cause of intestinal obstruction in children. Reduction of ileocolic intussusception using air or fluid enema is the standard of care. This likely distressing procedure is usually performed without sedation or analgesia, but practice variation exists.

OBJECTIVE: To characterize the prevalence of opioid analgesia and sedation and assess their association with intestinal perforation and failed reduction.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study reviewed medical records of children aged 4 to 48 months with attempted reduction of ileocolic intussusception at 86 pediatric tertiary care institutions in 14 countries from January 2017 to December 2019. Of …

Real-World Safety Of Neurohormonal Antagonist Initiation Among Older Adults Following A Heart Failure Hospitalization, Parag Goyal, Andrew R Zullo, Barbara Gladders, Chukwuma Onyebeke, Min Ji Kwak, Larry A Allen, Emily B Levitan, Monika M Safford, Lauren Gilstrap

Faculty, Staff and Student Publications

AIMS: To optimize guideline-directed medical therapy for heart failure, patients may require the initiation of multiple neurohormonal antagonists (NHAs) during and following hospitalization. The safety of this approach for older adults is not well established.

METHODS AND RESULTS: We conducted an observational cohort study of 207 223 Medicare beneficiaries discharged home following a hospitalization for heart failure with reduced ejection fraction (HFrEF) (2008-2015). We performed Cox proportional hazards regression to examine the association between the count of NHAs initiated within 90 days of hospital discharge (as a time-varying exposure) and all-cause mortality, all-cause rehospitalization, and fall-related adverse events over the …

A Novel Tool For Quantitative Measurement Of Distortion In Keratoconus, Mahesh R. Joshi, Kenrick J. Voison, Marianne Piano, Niall Farnon, Peter J. Bex

School of Health Professions

BACKGROUND: Keratoconus is associated with thinning and anterior protrusion of the cornea resulting in the symptoms of blurry and distorted vision. The commonly used clinical vision tests such as visual acuity and contrast sensitivity may not reflect the symptoms experienced in keratoconus and there are no quantitative tools to measure visual distortion. In this study, we used a quantitative test based on vernier alignment and field matching techniques to quantify visual distortion in keratoconus and assess its relation to corneal structural changes. METHODS: A total of 50 participants (25 keratoconus and 25 visually normal) completed the experiment where they aligned …

The Role Of High-Order Anharmonicity And Off-Diagonal Terms In Thermal Conductivity: A Case Study Of Multi-Phase Cspbbr3, Xiangdong Ding, Guimei Zhu, Yi Xia, Jie Ren, Jun Sun, Multiple Additional Authors

Mechanical and Materials Engineering Faculty Publications and Presentations

We investigate the influence of three- and four-phonon scattering, perturbative anharmonic phonon renormalization, and off-diagonal terms of coherent phonons on the thermal conductivity of CsPbBr3 phase change perovskite, by using advanced implementations and first-principles simulations. Our study spans a wide temperature range covering the entire structural spectrum. Notably, we demonstrate that the interactions between acoustic and optical phonons result in contrasting trends of phonon frequency shifts for the high-lying optical phonons in orthorhombic and cubic CsPbBr3 as temperature varies. Our findings highlight the significance of wavelike tunneling of coherent phonons in ultralow and glasslike thermal conductivity in halide perovskites.

Rebraiding Frayed Sweetgrass For Niijaansinaanik: Understanding Canadian Indigenous Child Welfare Issues As International Atrocity Crimes, Alyssa Couchie

Michigan Journal of International Law

The unearthing of the remains of Indigenous children on the sites of former Indian Residential Schools (“IRS”) in Canada has focused greater attention on anti-Indigenous atrocity violence in the country. While such increased attention, combined with recent efforts at redressing associated harms, represents a step forward in terms of recognizing and addressing the harms caused to Indigenous peoples through the settler-colonial process in Canada, this note expresses concern that the dominant framings of anti-Indigenous atrocity violence remain myopically focused on an overly narrow subset of harms and forms of violence, especially those committed at IRSs. It does so by utilizing …

Fact-Finding Without Rules: Habermas's Communicative Rationality As A Framework For Judicial Assessments Of Digital Open-Source Information, Matthew Gillett

Michigan Journal of International Law

Jürgen Habermas’s theory of “communicative rationality” (also known as “communicative action”) provides a promising conceptual apparatus through which to justify and validate the International Criminal Court’s consideration of the emerging phenomenon of digital open-source information. Because of its process-based and inclusive qualities, Habermas’s communicative rationality is particularly apposite for the dynamic nature of digital open-source information and the heterogenous range of actors and institutions which have relevant experiences and skills to contribute to the generation of norms and determinations regarding its role before the Court. This is important, as the International Criminal Court’s procedural framework is largely silent on digital …

International Law And The Right To Global Internet Access: Exploring Internet Access As A Human Right Through The Lens Of Iran’S Women-Life-Freedom Movement, Pegah Banihashemi

Chicago Journal of International Law

The speed of digital transformation creates major challenges for understanding and protecting digital technology-based human rights. While the internet may once have been a nice-to-have amenity, as societies become increasingly dependent on digital infrastructure, it has become a prerequisite to access fundamental human rights. Because the protection of internet access as a human right is lacking, individuals remain vulnerable to abuses, particularly by autocratic leaders.

This Essay uses the still-unfolding Iranian Women-Life-Freedom Movement to examine the consequences of internet deprivation. The Iranian regime’s brutal treatment of its citizens sparked widespread protests which were largely coordinated through social media, highlighting the …

Cerp: A Maritime Cyber Risk Decision Making Tool, E. Erstad, R. Hopcraft, J. D. Palbar, K. Tam

School of Engineering, Computing and Mathematics

An increase in the complexity of systems onboard ships in the last decade has seen a rise in the number of reported maritime cyber-attacks. To tackle this rising risk the International Maritime Organization published high-level requirements for cyber risk management in 2017. These requirements obligate organisations to establish procedures, like incident response plans, to manage cyber-incidents. However, there is currently no standardised framework for this implementation. This paper proposes a Cyber Emergency Response Procedure (CERP), that provides a framework for organisations to better facilitate their crew’s response to a cyber-incident that is considerate of their operational environment. Based on an …

The Future Of International Law Freedom Of Journalism: A Transitional Justice Framework, Edward L. Carter

Chicago Journal of International Law

The overwhelming majority of digital and physical attacks on journalists are done with impunity. This results in lower-quality journalism, less scrutiny of government, and less healthy societies and democracies. The international human rights law concept of transitional justice could bolster collective will and inform legal mechanisms to combat such impunity. Judges and investigators in several recent cases of attacks on journalists have invoked transitional justice concepts, including truth-telling, criminal investigations and prosecutions, reparations, and institutional reforms to guarantee non-recurrence. These mechanisms should be fully implemented to protect journalism at local, national, and international levels.

Speaking Up During The Covid‐19 Pandemic: Nurses' Experiences Of Organizational Disregard And Silence, Ruth Abrams, Anna Conolly, Emma Rowland, Ruth Harris, Bridie Kent, Daniel Kelly, Keith Couper, Jill Maben

School of Nursing and Midwifery

AIM: To critically examine nurses' experiences of speaking up during COVID-19 and the consequences of doing so. DESIGN: Longitudinal qualitative study. METHODS: Participants were purposively sampled to represent differing geographical locations, specialities, settings and redeployment experiences. They were interviewed (remotely) between July 2020 and April 2022 using a semi-structured interview topic guide. RESULTS: Three key themes were identified inductively from our analysis including: (1) Under threat: The ability to speak up or not; (2) Risk tolerance and avoidance: Consequences of speaking up; and (3) Deafness and hostility: Responses to speaking up. Nurses reported that their attempts to speak up typically …

Acinetobacter Baumannii Atcc 17978 Encodes A Microcin System With Antimicrobial Properties For Contact-Independent Competition, Fabiana Bisaro, Howard A Shuman, Mario F Feldman, Michael J Gebhardt, Stefan Pukatzki

2020-Current year OA Pubs

No abstract provided.

Influence Of Organics And Gas Mixing On Hydrogen/Brine And Methane/Brine Wettability Using Jordanian Oil Shale Rocks: Implications For Hydrogen Geological Storage, Amer Alanazi, Nurudeen Yekeen, Mujahid Ali, Muhammad Ali, Israa S. Abu-Mahfouz, Alireza Keshavarz, Stefan Iglauer, Hussein Hoteit

Research outputs 2022 to 2026

The substitution of fossil fuel with clean hydrogen (H₂) has been identified as a promising route to achieve net zero carbon emissions by this century. However, enough H₂ must be stored underground at an industrial scale to achieve this objective due to the low volumetric energy density of H₂. In underground H₂ storage, cushion gases, such as methane (CH₄), are required to maintain a safe operational formation pressure during the withdrawal or injection of H₂. The wetting characteristics of geological formations in the presence of H₂, cushion gas, …

Chinese-Speaking Undergraduates In Australia: A Lexical Approach To Teaching Academic Writing, Qin Chen, Anne Thwaite, Brian Moon

Research outputs 2022 to 2026

Chinese-speaking students enroll in Australian tertiary institutions in large numbers. Success for these international students is heavily dependent upon their mastering the conventions of academic writing in English. How best to ensure such mastery among EAL learners has been a matter of debate among tertiary educators and language specialists, with competing theories and methods proposed. This paper reports on an attempt to improve English academic writing through intensive lexical instruction, a method proposed by Ackermann & Chen (2013), Boers et al. (2016), Lewis (1993), Selivan (2018), Wray (2005, 2018) and others. Nine Chinese-speaking tertiary students were offered training in recognising …

Kinetics Of Wound Development And Healing Suggests A Skin-Stabilizing Effect Of Allogeneic Abcb5+ Mesenchymal Stromal Cell Treatment In Recessive Dystrophic Epidermolysis Bullosa, Elke Niebergall-Roth, Kathrin Dieter, Cristina Daniele, Silvia Fluhr, Maria Khokhrina, Ines Silva, Christoph Ganss, Markus H. Frank, Mark A. Kluth

Research outputs 2022 to 2026

Recessive dystrophic epidermolysis (RDEB) is a rare, inherited, and currently incurable skin blistering disorder characterized by cyclically recurring wounds coexisting with chronic non-healing wounds. In a recent clinical trial, three intravenous infusions of skin-derived ABCB5+ mesenchymal stromal cells (MSCs) to 14 patients with RDEB improved the healing of wounds that were present at baseline. Since in RDEB even minor mechanical forces perpetually provoke the development of new or recurrent wounds, a post-hoc analysis of patient photographs was performed to specifically assess the effects of ABCB5+ MSCs on new or recurrent wounds by evaluating 174 wounds that occurred after baseline. During …

An Improved Shallow Water Temperature Model For An Australian Tidal Wetland Environment Using Publicly Available Data, Kerry Staples, Steven Richardson, Peter J. Neville, Jacques Oosthuizen

Research outputs 2022 to 2026

Larval mosquito development is directly impacted by environmental water temperature. Shallow water less than 1 m deep is a common larval mosquito habitat. Existing mathematical models estimate water temperature using meteorological variables, and they range in complexity. We developed a modification of an existing one-layer heat balance model for estimating hourly water temperature and compared its performance with that of a model that uses only air temperature and water volume as inputs and that uses air temperature itself as an indicator of water temperature. These models were assessed against field measurements from a shallow tidal wetland—a known larval habitat—in southwest …

Mothers' Experiences Of A New Early Collaborative Intervention, The Eaci, In The Neonatal Period: A Qualitative Study, Charlotte Sahlén Helmer, Ulrika Birberg Thornberg, Thomas Abrahamsson, Evalotte Mörelius

Research outputs 2022 to 2026

Aim: To explore mothers' experiences of the EArly Collaborative Intervention. Background: Preterm birth puts a considerable emotional and psychological burden on parents and families. Parents to moderate and late premature infants have shorter stays at the neonatal intensive care unit and have described a need for support. The EArly Collaborative Intervention was developed to support parents with preterm infants born between gestational Weeks 30 to 36. In this study, mothers' experiences of the new intervention were explored. Design: A qualitative design guided by a reflexive thematic analysis according to Braun and Clarke. Interviews were individually performed with 23 mothers experienced …

Muscle Fatigue During Maximal Eccentric-Only, Concentric-Only, And Eccentric-Concentric Bicep Curl Exercise With Automated Drop Setting, James L. Nuzzo, Matheus D. Pinto, Kazunori Nosaka

Research outputs 2022 to 2026

Connected adaptive resistance exercise (CARE) machines are new technology purported to adjust resistance exercise loads in response to muscle fatigue. The present study examined muscle fatigue (strength loss, fatigue perceptions) during maximal eccentric-only (ECCmax-only), concentric-only (CONmax-only), and coupled ECC-CON (ECCmax-CONmax) bicep curl exercise on a CARE machine. Eleven men and nine women completed the three protocols in separate sessions and in random order. All protocols included 4 sets of 20 maximal effort muscle contractions. Strength loss was calculated as Set 4 set end load minus Set 1 highest load. The CARE machine's algorithm adjusted resistances automatically, permitting continued maximal effort …

Terrain Characterization Via Machine Vs. Deep Learning Using Remote Sensing, Jordan Ewing, Thomas Oommen, Jobin Thomas, Anush Kasaragod, Richard Dobson, Colin Brooks, Paramsothy Jayakumar, Michael Cole, Tulga Ersal

Michigan Tech Publications, Part 1

Terrain traversability is critical for developing Go/No-Go maps for ground vehicles, which significantly impact a mission’s success. To predict the mobility of terrain, one must understand the soil characteristics. In-situ measurements performed in the field are the current method of collecting this information, which is time-consuming, costly, and can be lethal for military operations. This paper investigates an alternative approach using thermal, multispectral, and hyperspectral remote sensing from an unmanned aerial vehicle (UAV) platform. Remotely sensed data combined with machine learning (linear, ridge, lasso, partial least squares (PLS), support vector machines (SVM), and k nearest neighbors (KNN)) and deep learning …

Interleukin-18 Signaling Promotes Activation Of Hepatic Stellate Cells In Mouse Liver Fibrosis, Jana Knorr, Joel D. Schilling, Et Al.

2020-Current year OA Pubs

BACKGROUND AND AIMS: Nucleotide-binding oligomerization domain-like receptor-family pyrin domain-containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis. Mechanisms and downstream signaling remain incompletely understood. Here, we studied the role of IL-18 in hepatic stellate cells (HSCs), and its impact on liver fibrosis.

APPROACH AND RESULTS: We observed significantly increased serum levels of IL-18 (128.4 pg/ml vs. 74.9 pg/ml) and IL-18 binding protein (BP; 46.50 ng/ml vs. 15.35 ng/ml) in patients with liver cirrhosis compared with healthy controls. Single cell RNA sequencing data showed that an immunoregulatory subset of murine HSCs highly expresses Il18 and Il18r1 . …

A Pentasaccharide For Monitoring Pharmacodynamic Response To Gene Therapy In Gm1 Gangliosidosis, Pamela Kell, Rohini Sidhu, Mingxing Qian, Sonali Mishra, Dennis J Dietzen, Jingqin Luo, Jean E Schaffer, Daniel S Ory, Xuntian Jiang, Et Al.

2020-Current year OA Pubs

BACKGROUND: GM1 gangliosidosis is a rare, fatal, neurodegenerative disease caused by mutations in the GLB1 gene and deficiency in β-galactosidase. Delay of symptom onset and increase in lifespan in a GM1 gangliosidosis cat model after adeno-associated viral (AAV) gene therapy treatment provide the basis for AAV gene therapy trials. The availability of validated biomarkers would greatly improve assessment of therapeutic efficacy.

METHODS: The liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used to screen oligosaccharides as potential biomarkers for GM1 gangliosidosis. The structures of pentasaccharide biomarkers were determined with mass spectrometry, as well as chemical and enzymatic degradations. Comparison of LC-MS/MS data …

Replicative Acinetobacter Baumannii Strains Interfere With Phagosomal Maturation By Modulating The Vacuolar Ph, Jesus S. Distel, Gisela Di Venanzio, Joseph J. Mackel, David A. Rosen, Mario F. Feldman

2020-Current year OA Pubs

Bacterial pneumonia is a common infection of the lower respiratory tract that can afflict patients of all ages. Multidrug-resistant strains of Acinetobacter baumannii are increasingly responsible for causing nosocomial pneumonias, thus posing an urgent threat. Alveolar macrophages play a critical role in overcoming respiratory infections caused by this pathogen. Recently, we and others have shown that new clinical isolates of A. baumannii, but not the common lab strain ATCC 19606 (19606), can persist and replicate in macrophages within spacious vacuoles that we called Acinetobacter Containing Vacuoles (ACV). In this work, we demonstrate that the modern A. baumannii clinical isolate 398, …

The Death Penalty In The New Omani Penal Code Passed By Royal Decree 7/2018 From Shariah Perspective: An Analytical Study / Malak Sultan Mohamed Alhabsi, Mohamed Alhabsi Malak Sultan

Student Works (2020-2029)

The problem of the study is summed up in the legislation of the capital punishment in the new Omani Penal Code enacted by the Royal Decree (7/2018), despite the wide intellectual controversy stirred by the capital punishment (death penalty) because of the call of human rights organizations and many jurisprudents and jurists for the need to prevent the capital punishment. The study adopted the inductive methodology, and the analytical methodology. The study aimed to know what the capital punishment is, its legitimacy and the wisdom behind it in Islam, clarify the amendments to the new Omani Penal Code, identify its …

Meet Your New Mda Editor, Michelle C. Dziurgot Dds

The Journal of the Michigan Dental Association

Dr. Michelle C. Dziurgot introduces herself as the new editor-in-chief of the Journal of the Michigan Dental Association. She shares her background, including her dental career, writing experience, and leadership roles. Dr. Dziurgot expresses her commitment to promoting dentistry and engaging with the dental community through the journal. She emphasizes her passion for the field and her willingness to serve the members of the Michigan Dental Association.

The 2023 Mda Annual Session: Good Times, Great Meeting, David Foe Ma

The Journal of the Michigan Dental Association

The 2023 MDA Annual Session was a successful event, with over 2,600 dental professionals attending in downtown Grand Rapids. Highlights included engaging keynote addresses, informative CE courses, a bustling exhibit hall, and various social events. The MDA Foundation's Sparkling Smiles Celebration raised funds to support dental scholarships and improve access to care. The event provided valuable networking opportunities and resources for attendees.

2023 June, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for June of 2023.

Effects Of Atrioventricular Optimization On Left Ventricular Reverse Remodeling With Cardiac Resynchronization Therapy: Results Of The Smart-Crt Trial., Michael R Gold, Kenneth A Ellenbogen, Christophe Leclercq, Jonathan Lowy, Seth J Rials, Morio Shoda, Gery Tomassoni, Ziad Issa, Jean-Francois Sarrazin, John M Jennings, Devi G Nair, Nicholas Wold, Patrick Yong, Michelle M Harbin, Kenneth M Stein, Angelo Auricchio

Heart and Vascular Articles

BACKGROUND: The role of atrioventricular optimization (AVO) to improve cardiac resynchronization therapy outcomes remains controversial. Previous post hoc analyses of a multicenter trial showed that measures of electrical dyssynchrony (right ventricular-left ventricular [LV] or LV electrical delay durations) are associated with patients who benefit from AVO.

METHODS: This was a global, multicenter, prospective, randomized trial of de novo cardiac resynchronization therapy implant patients with an right ventricular-LV duration ≥70 ms to determine whether AVO results in greater reverse remodeling. Patients were randomized 1:1 for either an AVO algorithm (SmartDelay) that determines atrioventricular delay and pacing chamber, biventricular or LV only, …

How And Why To Write For The Journal Of Case Learning And Exceptional Learners, Aftynne E. Cheek

Journal of Case Learning & Exceptional Learners

The Journal of Case Learning and Exceptional Learners (JCLEL) is an open-access, double-blind, peer-reviewed online journal that publishes case studies, case study learning research, and resources. JCLEL focuses on students with intellectual and developmental disabilities and extensive support needs. In this article, we discuss how these unique case studies can be used in special education teacher preparation and why authors should consider publishing with JCLEL. Information about how to write case studies that can be used for educational purposes and that adhere to the case study frameworks will be provided. The authors also present a general overview of the journal, …

Multilingual Learners' And Their Teachers' Perceptions Of Culturally Responsive-Sustaining Practices In The Mainstream Classroom: A Mixed-Method Approach, Nicki K. Gonias

Theses & Dissertations

The number of multilingual learners (MLs) is on the rise in the United States, especially in schools located in New York State and Long Island. However, many general education teachers lack the necessary training and certification to teach these diverse students effectively. In response, New York State has developed the NYS Culturally Responsive-Sustaining (CR-S) Education Framework to address the gaps in teaching practices. The implementation varies across districts on Long Island. To gain a deeper understanding, I conducted this study to investigate the perceptions of MLs and their teachers regarding CR-S pedagogical approaches in mainstream classrooms. The study involved surveys …

Ethical Leadership And Employee Unethical Behavior: A Dual-Processing Model, Chenjing Gan, Chi-Ying Cheng, Yandong Chai, Linbo Yang

Research Collection School of Social Sciences

Purpose – This study seeks to apply a dual-processing model to understand how ethical leadership prohibits employee unethical behavior through both employee deontic justice and distributive justice. Design/methodology/approach – A survey research was conducted with 62 supervisors and 244 subordinates of 17 firms collected at 2 time points separated by approximately 3 weeks in People’s Republic of China. Findings – A multilevel modeling analysis was used to test the dual-processing model. The results showed that both employee deontic justice (moral intuition process) and distributive justice (deliberate reasoning process) significantly mediate the negative relationship between ethical leadership and employee unethical behavior. …

Dolling-Up Under Disease Threats: Do Pathogen Threats Motivate Attractiveness Signaling?, Kai Lin Lynn Tan, Michal Folwarczny, Agata Gasiorowska, Norman P. Li

Research Collection School of Social Sciences

Under high pathogen threat, it is adaptive for humans to find mates with high immunocompetence. Supporting this, research shows that pathogen cues increase humans’ preference for physical attractiveness—an indicator of a well-functioning immune system—among their potential mates. Building on this literature, we examined whether exposure to videos depicting pathogens (vs. a control video of nature scenery) triggers the desire to signal one’s physical attractiveness. We tested this prediction in four experiments, including two well-powered preregistered ones. In Experiment 1, we examined how pathogen cues influenced the desire for cosmetic surgery and the amount of time and money participants are willing …