Digital Commons Network^™

Ecological Drift And Host Filtering Jointly Structure Foliar Endophytes During Ecosystem Development., Caio César Pires De Paula, Petr Macek, Milan Varsadiya, Jakub Borovec, Mehmet A. Balkan, Brett S. Younginger, Daniel J. Ballhorn, Tomáš Picek, Tomáš Hájek, Jan Frouz, Jiří Bárta, Dagmara Sirová

Biology Faculty Publications and Presentations

Foliar endophytes contribute to plant nutrient acquisition, stress tolerance, and pathogen resistance, yet their responses to ecosystem-level processes remain poorly understood. Using a space-for-time substitution design, we investigated bacterial and fungal community dynamics in the foliar endosphere of four phylogenetically distinct plant hosts across a well-characterized successional chronosequence.

Understanding Stakeholders’ Perceptions Of Liberia’S Accelerated Learning Program: A Generic Qualitative Study, Aagon Fremling Tingba, Jr.

Walden Dissertations and Doctoral Studies

No abstract provided.

Exploring How Parental Substance Abuse Experiences Shape Black Women’S Interpersonal Relationships, Samele Mayfield

Walden Dissertations and Doctoral Studies

No abstract provided.

Serological Evidence Of Onchocerca Volvulus Exposure And Entomological Indicators Of Parasite Transmission, Didier Kapuku Bakajika

Walden Dissertations and Doctoral Studies

No abstract provided.

Development Of An Evidence Based Pressure Ulcer Prevention Bundle For The Medical Surgical Unit, Fanhelea Morency

Walden Dissertations and Doctoral Studies

No abstract provided.

Breaking Barriers: The Impact Of Recruitment And Retention On Black Educator Representation In K–12 Schools And Strategies For Advancing Equity, Wynter Williams-Adams

LMU Theses and Dissertations

The underrepresentation of African American teachers in California K–12 public schools remain a persistent and systemic issue that directly impacts student outcomes and school climate. This qualitative study investigates the barriers that affect both the recruitment and retention of African American teachers across multiple stages of the educator pipeline, including college seniors considering teaching, early-career teachers, veteran educators, and former teachers who exited the profession. Using a grounded theory approach (Glaser & Strauss, 1967; Charmaz, 2014) and guided by Critical Race Theory (CRT) (Bell, 1992; Crenshaw, 1996), Cultural Reproduction Theory (Bourdieu, 1977), and Organizational Theory (Fayol, 1949; Capper, 2018) this …

Optimization And Safety Protocols For An Acetone Production Plant, Holley J. Garrison

Honors Theses

The proposed acetone production plant, scheduled for start-up in 2028, is capable of producing 3,750 kg/h of 99.9 wt% acetone. Using an endothermic catalytic dehydrogenation reaction, a feed of isopropyl alcohol (IPA) is reacted to produce 30,000 metric tons per year (MT/y) of acetone. Initial design and economic analysis of this process found that this plant will not be economically viable due to its Net Present Value (NPV) of -$132M. Optimization efforts prioritized reductions in raw materials and improved product recovery. Several optimizations were performed to reduce the feed rate, including switching to the low temperature catalyst, shortening the reactor …

Identifying Novel Gene Dysregulation Associated With Opioid Overdose Death: A Meta-Analysis Of Differential Gene Expression In Human Prefrontal Cortex, Javan K Carter, Bryan C Quach, Caryn Willis, Melyssa S Minto, Dana B Hancock, Janitza Montalvo-Ortiz, Olivia Corradin, Ryan W Logan, Consuelo Walss-Bass, Brion S Maher, Eric Otto Johnson

Faculty, Staff and Student Publications

Only recently have human postmortem brain studies of differential gene expression (DGE) associated with opioid overdose death (OOD) been published; sample sizes from these studies have been modest (N = 40-153). To increase statistical power to identify OOD-associated genes, we leveraged human prefrontal cortex RNA-seq data from four independent OOD studies and conducted a transcriptome-wide DGE meta-analysis (N = 272). Using a unified gene expression data processing and analysis framework across studies, we meta-analyzed 20, 098 genes and found 335 significant differentially expressed genes (DEGs) by OOD status (false discovery rate <  0.05). Of these, 66 DEGs were among the list of 303 genes reported as OOD-associated in prior prefrontal cortex molecular studies (e.g., genes/gene families OPRK1, NPAS4, DUSP, EGR). The remaining 269 DEGs were not previously reported (e.g., NR4A2, SYT1, HCRTR2, BDNF). There was little evidence of genetic drivers for the observed differences in gene expression between opioid addiction cases and controls. Enrichment analyses for the DEGs across molecular pathway and biological process databases highlight an interconnected set of genes and pathways linked to orexin and tyrosine kinase receptors through MEK/ERK/MAPK signaling to affect neuronal plasticity.

Homelessness In The Caribbean: From Colonial Roots To Rights-Based Responses, Wilmy Dessalines, Tamar Ezer, Gabriela Valentín Diaz

University of Miami International and Comparative Law Review

This Article provides an analysis of homelessness across four Caribbean localities—the Dominican Republic, Haiti, Jamaica, and Puerto Rico. Each locality brings a diverse history connected to colonial legacies and realities from Spain, France, the United Kingdom, and the United States. They capture a cross-section of the Caribbean and reveal that homelessness is shaped by legal and governance systems rooted in colonial inheritance that promote exclusion over social protection: from vagrancy laws that regulate presence in public space to land systems that legalize dispossession and facilitate displacement. Laws punishing vagrancy and life-sustaining activities serve as instruments of social control that systematically …

Plastic Material Analysis And Bonding In Small Aquatic Vessels, Andrew R. Orr

Honors College Theses

This project presents the design and development of a suitable vessel for small-scale aquatic applications. The developed project is used for a remote-controlled duck hunting system, and the parameters of the design are based on the requirements for the system as a whole. Traditionally, plastics are fabricated using blow molding to create a single seamless form. However, for small-scale prototyping with limited resources, this method of fabrication is unsustainable for short-term, non-industrial design applications. As a result, an existing longer hull is selected and shortened to meet the required project length. The project evaluates multiple initial hull designs, ultimately selecting …

Tissue Doppler Imaging, Pulmonary Haemodynamics And Conventional Echocardiographic Indices For Early Bronchopulmonary Dysplasia Prediction In Preterm Infants: A Prospective Observational Feasibility Study, Wisam Muhsen, Joanne Hosking, Jos M. Latour, Eirik Nestaas

School of Nursing and Midwifery

Background/Objectives: Bronchopulmonary dysplasia (BPD) remains a major complication of prematurity, yet no prediction model incorporating echocardiographic assessment of right ventricle (RV) function and pulmonary haemodynamics exists. This study aimed to identify clinical and echocardiographic candidate variables of BPD to inform the design of a future multicentre study for BPD prediction model construction. Methods: This prospective observational feasibility study recruited preterm infants born before 32 weeks of gestation. Echocardiographic scans were performed at Day 5 and Day 9 postnatally. Candidate variables across six domains, clinical, RV systolic, diastolic, and global function, pulmonary-haemodynamics, and patent ductus arteriosus (PDA) variables, were evaluated using …

Spad Camera Image Analysis, Pratheen Reddy Pininti

Electronic Theses and Dissertations 2020 - Present

I present a thorough noise characterization of the Canon MS-500, a Single-Photon Avalanche Diode (SPAD) camera system, tested under both lit and dark conditions. The camera outputs 10-bit digital number (DN) values produced by an internal processing pipeline whose design is not publicly documented. All analyses in this thesis therefore describe the camera’s DN output — the signal that any downstream detection, tracking, or classification system will actually receive — rather than the photon-counting statistics of the underlying SPAD array. All computations were performed on the native 10-bit data. Where a measured quantity has a known photon-counting analog, the relationship …

Draft Final Butte Mine Waste Repository Operation And Maintenance (O&M) Plan, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Correction: Case, R.P.; Hupy, J.P. Methods For Gis-Driven Airspace Management: Integrating Unmanned Aircraft Systems (Uass), Advanced Air Mobility (Aam), And Crewed Aircraft In The Nas. Drones 2026, 10, 82, Ryan P. Case, Joseph P. Hupy

Aviation Technology Graduate Student Publications

A correction has been made to Section 2. Materials and Methods, paragraph 4.

In 2023, a Purdue University DJI M300 was conducting an RGB (Red, Green, Blue) mapping mission near the Purdue water tower on the Northwest side of campus. Just after 5:00 PM Eastern, the DJI M300 UAS operator was alerted of an aircraft entering their mapping mission airspace and took action to increase separation until the threat had passed. The DJI M300 UAS team had appropriate LAANC approval and waivers in place to conduct their mission and had a VHF radio monitoring KLAF Tower communications. The DJI M300 …

Lived Experiences Of Homebound Adults With Health Access Needs, Margaret Henderson-Lee

Electronic Theses and Dissertations Archive

Homebound adults represent a medically vulnerable and rapidly growing population at heightened risk for unmet healthcare needs. Although quantitative studies document disparities in utilization and outcomes, less is known about how homebound individuals experience healthcare access. Grounded in Husserlian transcendental phenomenology, this qualitative study explored the lived experiences of homebound adults facing healthcare access barriers and examined how those experiences align with Levesque et al.’s patient-centered conceptual framework of access. Twenty homebound adults were recruited from a single residential care setting in the southeastern United States. Data were collected through semi-structured interviews and analyzed using an inductive phenomenology approach. Initial …

Oxytocin And Vasopressin Receptors Mediate Dopamine Release In The Nucleus Accumbens, Rebecca Chari Crenshaw

Electronic Theses and Dissertations Archive

Oxytocin (OXT) is a potential therapeutic target for substance use disorders due to its modulatory effects on mesolimbic dopamine function. While OXT activity in the nucleus accumbens (NAc) influences dopamine release, the receptor mechanisms underlying these effects remain unclear. Oxytocin receptors (OXTRs) and vasopressin 1A receptors (V1aRs) are both expressed in the NAc and may differentially regulate dopamine function. This study examined how selective activation and blockade of OXTRs and V1aRs within the NAc modulate phasic and tonic dopamine release using in vivo amperometry in male and female mice. Intra-NAc OXT decreased phasic, but not tonic, dopamine release. Similarly, activation …

Mutual Redevelopment Houses, Inc. V. Manyevitch

All Decisions

In a licensee holdover proceeding in a cooperative PHFL Article V (Mitchell-Lama), the landlord and tenant both moved for summary judgment regarding succession rights. Tenant, the spouse of a prior successor, was granted summary judgment, with the court finding she met spousal succession requirements under Section 210(d)(i) of the City Agreement, notwithstanding the prior successor's lack of formal shares or an occupancy agreement. The landlord's motion for summary judgment was granted against co-occupant, who failed to provide admissible evidence for Braschi-type succession, resulting in a possessory judgment against him. The petition was dismissed against John and Jane Doe. The court …

The Battle Of Tupelo Hospital Cemetery National Register Nomination, Madeline K. Weems

Electronic Theses and Dissertations

On July 14, 1864, the Battle of Tupelo, or the Battle of Harrisburg as it is also known, occurred within fifteen miles of the community of Palmetto in northeast Mississippi. As the battle ensued, wounded and dying soldiers were transported to different sites in and around Tupelo, including the home of Dr. William Henry and Jane Calhoun in Palmetto that served as the main hospital. The bodies of some of those soldiers still remain on the former Calhoun Plantation, including the grave of D. D. Drake. This public history capstone thesis evaluates this Civil War era cemetery’s history and integrity, …

Butte Priority Soils Operable Unit (Bpsou) 2026 Monthly Progress Report. Consent Decree For The Butte Priority Soils Operable Unit. Civil Action No. Cv 89-039-Bu-Seh, Josh Bryson

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Elementary Public School Principals’ Decision Process For Hiring Teachers In The U.S. Mid-Atlantic Region, Charmaine Gray

Walden Dissertations and Doctoral Studies

No abstract provided.

Strategies Leaders In The Financial Industry Use To Create A More Diverse, Equal, And Inclusive Culture To Improve Business Performance, Wendy Lynne Hines

Walden Dissertations and Doctoral Studies

No abstract provided.

Improving Esi Triage Accuracy In The Emergency Department, Taibat Mursal Verdi

Walden Dissertations and Doctoral Studies

No abstract provided.

Using Forensic Psycholinguistic Analysis To Detect Dark Tetrad Traits In Police Interviews Of Murder Suspects, Amanda Janette Borman-Ballard

Walden Dissertations and Doctoral Studies

No abstract provided.

Inner City Black Male Mentors’ Narratives Of Emerging Adulthood And Civic Engagement, Andrea Maria White

Walden Dissertations and Doctoral Studies

No abstract provided.

Prevalence Of Adverse Events Following T-Cell Redirecting Therapies In Patients With Metastatic Castration-Resistant Prostate Cancer: A Pooled Analysis, Abhiraj Saxena, Marc Yorker, Nicholas Zorko, Vivek Narayan, Bilal Siddiqui, Biren Saraiya, William Tester, Patrick Mille, Amy Shaver, Nikita Nikita, Grace Lu-Yao, W. Kevin Kelly, Kevin K. Zarrabi

Department of Medical Oncology Faculty Papers

BACKGROUND: T-cell redirecting therapies, including T-cell engagers (TCEs) and Chimeric Antigen Receptor T-cell (CAR-T), are under investigation in metastatic castration-resistant prostate cancer (mCRPC). Despite their promising therapeutic potential, these therapies remain in early stages of development due to treatment-related adverse events (TRAEs). This study aims to quantify the frequency and severity of adverse events in clinical trials with a pooled analysis.

MATERIALS AND METHODS: A systematic search of PubMed, CINHAL, Scopus, and Ovid was conducted to identify clinical trials evaluating TCEs or CAR-T in patients with mCRPC. Types and frequencies of TRAEs were collected and analyzed using a random-effects model. …

Enhancing Psychiatry Residents’ Knowledge And Comfort With Clozapine Prescribing Through Educational Interventions, Christopher Stewart, Alexander Hunter, Faith Franzwa, Quan Huynh, Jennifer Stettler, Nauman Ashraf, Dawny M. Barnhart

Student Publications

Introduction: Clozapine is the most effective antipsychotic for treatment-resistant schizophrenia but remains underutilized due to safety concerns and monitoring complexity. Recent discontinuation of the Clozapine Risk Evaluation and Mitigation Strategy (REMS) program reduced regulatory barriers but shifted responsibility for monitoring to clinicians. Psychiatry residents may lack adequate training and confidence to prescribe clozapine safely in this new context. The goal of this study is to evaluate the impact of a structured educational intervention on psychiatry residents’ knowledge of clozapine prescribing and management.

Methods: This study was a single-institution quality improvement study using a pre-post design. Participants were psychiatry residents from …

Mechanisms Underlying Diversity In Bacterial Biofilms, Jacob David Holt

Dartmouth College Ph.D Dissertations

Bacteria commonly exist in natural environments as communities of multiple strains and species attached to surfaces and encased in an extracellular matrix of DNA, protein, and polysaccharides–termed biofilms. These biofilms contribute to diverse functions, from ocean carbon cycling via chitin degradation to pathogenic processes such as wound or implant colonization. The molecular mechanisms governing biofilm formation and composition have been well characterized in model pathogenic organisms, yet the extent to which aspects of biofilm formation contribute to the assembly and maintenance of diverse communities remains less well understood. Using microfluidics, confocal microscopy, and model biofilm-forming bacteria, this thesis details how …

Modeling Individual Self-Protective Behavior During Epidemics, Geonsik Yu, Michael J. Garee, Mario Ventresca, Yuehwern Yih

Faculty Publications

Protecting public health from infectious diseases requires collective action, as individual behaviors—such as vaccination and mask-wearing—directly influence disease dynamics. During the COVID-19 pandemic, unexpected public responses often undermined the effectiveness of interventions, highlighting the need to understand collective behavioral patterns and motivations to design more effective mitigation strategies. This study presents an agent-based simulation model that captures how individuals adjust self-protective behaviors based on evolving opinions about disease risk and examines how these decisions interact with external factors, such as public health interventions, to shape collective outcomes. To improve the representativeness of the simulated population, multiple datasets were integrated to …

Development Of Novel Plasma Proteomic Biomarkers For Cancer-Associated Thrombosis In An Advanced Cancer Cohort, Preeti, Mrinal Ranjan, Dang Pham, Juan L Bueno, Micheline M Resende, Michael E Scheurer, Christopher I Amos, Chao Cheng, Ang Li

Faculty, Staff and Students Publications

Background: Existing risk models for cancer-associated thrombosis (CAT) show suboptimal performance in selective high-risk populations with cancer. Affinity-based plasma proteomics offers a novel approach for detecting CAT risk.

Objectives: To identify plasma biomarkers for CAT using proximity extension assays in an advanced cancer cohort.

Methods: We performed a nested case-control study using the Olink Explore HT panel. The final cohort included 57 patients with CAT and 113 matched control patients from 5 selected cancer types who had samples collected between cancer diagnosis and chemotherapy initiation. Random survival forest model was used to assess nonlinear associations with CAT in 5416 normalized …

Gaboxadol Increases Resting Theta And Alpha Power Without Affecting Evoked Responses In Fragile X Syndrome In A Home-Based Setting., Lisa A. De Stefano, Hyeonseok Kim, Craig A. Erickson, Lauren M. Schmitt, Kelli C. Dominick, Ernest V. Pedapati, Richard Huckle, Robert Wilson, Walker S. Mckinney Ph.D., Debra L. Reisinger, Meredith N. Nelson, Ashley E. Dapore, Paul S. Horn, Makoto Miyakoshi

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Fragile X syndrome (FXS) lacks FDA-approved treatments despite various small molecules contributing to phenotypic rescue in the FMR1 knockout (KO) mouse model. Translation from the mouse model has been hampered by phenotypic heterogeneity that contributes to participation barriers among participants who are most affected and may be unable to regularly visit the research laboratory. The current study utilized a crossover design to test the acute neural and behavioral effects of a single 10 mg dose of gaboxadol and the reliability of electroencephalography (EEG) and behavioral data collected in participant homes compared to the clinic.

METHODS: Ten adult males with …