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Uab Earns Women's Choice Award For "Best Hospital" Designation For Eight Areas, Public Relations

Browse All News

No abstract provided.

Fs Steering Committee Agenda 2024-01-17, Northern Illinois University

Faculty Senate Archives

No abstract provided.

Ecological Diversification In An Adaptive Radiation Of Plants: The Role Of De Novo Mutation And Introgression, Benjamin Stone, Carolyn A. Wessinger

Faculty Publications

Adaptive radiations are characterized by rapid ecological diversification and speciation events, leading to fuzzy species boundaries between ecologically differentiated species. Adaptive radiations are therefore key systems for understanding how species are formed and maintained, including the role of de novo mutations versus preexisting variation in ecological adaptation and the genome-wide consequences of hybridization events. For example, adaptive introgression, where beneficial alleles are transferred between lineages through hybridization, may fuel diversification in adaptive radiations and facilitate adaptation to new environments. In this study, we employed whole-genome resequencing data to investigate the evolutionary origin of hummingbird-pollinated flowers and to characterize genome-wide patterns …

Treatment Effects Of N-Acetyl Cysteine On Resting-State Functional Mri And Cognitive Performance In Patients With Chronic Mild Traumatic Brain Injury: A Longitudinal Study, Faezeh Vedaei, Andrew B. Newberg, M. Alizadeh, George Zabrecky, Emily Navarreto, Chloe Hriso, Nancy Wintering, Feroze Mohamed, Daniel A. Monti

Marcus Institute of Integrative Health Faculty Papers

Mild traumatic brain injury (mTBI) is a significant public health concern, specially characterized by a complex pattern of abnormal neural activity and functional connectivity. It is often associated with a broad spectrum of short-term and long-term cognitive and behavioral symptoms including memory dysfunction, headache, and balance difficulties. Furthermore, there is evidence that oxidative stress significantly contributes to these symptoms and neurophysiological changes. The purpose of this study was to assess the effect of N-acetylcysteine (NAC) on brain function and chronic symptoms in mTBI patients. Fifty patients diagnosed with chronic mTBI participated in this study. They were categorized into two groups …

The Bg News January 17, 2024, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 17, 2024. Volume 103-Issue 13.

Post-Exposure Intranasal Ifnα Suppresses Replication And Neuroinvasion Of Venezuelan Equine Encephalitis Virus Within Olfactory Sensory Neurons, Matthew D Cain, N Rubin Klein, Xiaoping Jiang, Hamid Salimi, Qingping Wu, Mark J Miller, William B Klimstra, Robyn S Klein

2020-Current year OA Pubs

BACKGROUND: Venezuelan Equine Encephalitis virus (VEEV) may enter the central nervous system (CNS) within olfactory sensory neurons (OSN) that originate in the nasal cavity after intranasal exposure. While it is known that VEEV has evolved several mechanisms to inhibit type I interferon (IFN) signaling within infected cells, whether this inhibits virologic control during neuroinvasion along OSN has not been studied.

METHODS: We utilized an established murine model of intranasal infection with VEEV and a repository of scRNAseq data from IFN-treated OSN to assess the cellular targets and IFN signaling responses after VEEV exposure.

RESULTS: We found that immature OSN, which …

Draft Genomes Of 12 Bifidobacterium Isolates From Human Ibd Fecal Samples, Cole E Souza, Nicole E Jacobson, Michelle A An, Lindsay Droit, Alejandro A Vega, Mariel Rosales, Kathie A Mihindukulasuriya, Karina Pastrana, Scott A Handley, Miles Parkes, Joanna Rimmer, David Wang, Elizabeth A Dinsdale, Robert A Edwards, Anca M Segall

2020-Current year OA Pubs

Twelve

Educating For Capability And Preparing For Practice: Integrating Theory And Skills, Sally Hanks, Tom Gale, Harry Carter, Robert Johnson

Peninsula Medical School

Capability is the ability to perform clinical skills in ever-changing real world contexts, adapting to challenges and integrating technical and non-technical skills and competencies, for example, cannulating an uncooperative patient at night. Going beyond teaching competency and ensuring capability is imperative, as recommended by the national outcomes for medical graduates. A course on intravenous cannulation was developed with e-learning modules and high-fidelity complex simulation scenarios, aiming to promote capability in practice. The course delivered an intravenous cannulation e-learning package between two practical simulations to 10 final-year medical students. The hybrid simulation design consisted of an actor with a bespoke cannulation …

Cdk4/6 Inhibition Sensitizes Intracranial Tumors To Pd-1 Blockade In Preclinical Models Of Brain Metastasis, Naema Nayyar, Magali A De Sauvage, Jane Chuprin, Emily M Sullivan, Mohini Singh, Britney S Zhang, Keith A Daniels, Christopher Alvarez-Breckenridge, Ashish Dahal, Michael A Brehm, Priscilla K Brastianos

Faculty, Staff and Student Publications

PURPOSE: Brain metastases are associated with high morbidity and are often resistant to immune checkpoint inhibitors. We evaluated whether CDK4/6 inhibitor (CDKi) abemaciclib can sensitize intracranial tumors to programmed cell death protein 1 (PD-1) inhibition in mouse models of melanoma and breast cancer brain metastasis.

EXPERIMENTAL DESIGN: Treatment response was evaluated in vivo using immunocompetent mouse models of brain metastasis bearing concurrent intracranial and extracranial tumors. Treatment effect on intracranial and extracranial tumor-immune microenvironments (TIME) was evaluated using immunofluorescence, multiplex immunoassays, high-parameter flow cytometry, and T-cell receptor profiling. Mice with humanized immune systems were evaluated using flow cytometry to study …

2024-01-17 An Evening In Vegas: Rha’S Casino Night, Abdullah El-Sherbeeny

The Spectator Online

No abstract provided.

Pressing Need Of Precision Care In Her2-Positive Colorectal Cancer: The Elephant In The Room, Kanwal P S Raghav, Jonathan M Loree, Scott Kopetz

Faculty, Staff and Student Publications

Although dual HER2 inhibition has shown promising clinical activity in patients with RAS wild-type HER2-positive metastatic colorectal cancer, predictive biomarkers of response/resistance are less well characterized. Activating HER2/RTK/MAPK genomic alterations appears to blunt the clinical benefit of dual anti-HER2 therapy and may hold a potential albeit partial role in patient selection. See related article by Randon et al., p. 436.

Comparison Of Three Rapid Diagnostic Tests For Bloodstream Infections Using Benefit-Risk Evaluation Framework (Bed-Frame), Richard D Smith, Min Zhan, Shanshan Zhang, Surbhi Leekha, Anthony Harris, Scott Evans, Robert K Ernst

Faculty, Staff and Student Publications

Rapid diagnostic tests (RDTs) for bloodstream infections have the potential to reduce time to appropriate antimicrobial therapy and improve patient outcomes. Previously, an in-house, lipid-based, matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) method, Fast Lipid Analysis Technique (FLAT MS), has shown promise as a rapid pathogen identification method. In this study, FLAT MS for direct from blood culture identification was evaluated and compared to FDA-cleared identification methods using the Benefit-risk Evaluation Framework (BED-FRAME) analysis. FLAT MS was evaluated and compared to Bruker Sepsityper and bioMérieux BioFire FilmArray BCID2 using results from a previous study. For this study, 301 …

An Analysis Of Fathers’ And Toddlers’ Behaviors During Shared Book Reading, Caitlin Marie Kelly

Theses and Dissertations

Shared book reading interactions between parents and their children have been studied to draw correlations to a child’s vocabulary growth, language development, mathematical scores, and socioemotional skills. However, there is a lack of research regarding fathers’ and toddlers’ engagement and behaviors during shared book reading interactions. The current study investigated and analyzed father and toddler interactions during shared book reading. The data was collected from a larger longitudinal study. Seven father-child dyads participated in the study (Mage = 35 years; range = 30-43 years). The children included four males and two females, and up to two videos were collected for …

From Ethical Subject To Self Of Eros: The Aesthetics Of Existence From Foucault To Agamben, Renjie Ye Ye Renjie, Ph. D., Is A Lecturer In Department Of Philosophy In School Of Public Administration, Nanjing Normal University, Whose Present Research Interests Are Continental Philosophy, History Of Western Political Thought And Contemporary Literary Theory.

Theoretical Studies in Literature and Art

The aesthetics of existence is at the core of Foucault's later ethical genealogy, in which the superiority of the free subject in the self-construction over power can establish the superiority of the ethical subject over the moral subject and that of the governance of the self over the governance of others. Agamben's concept of the “form-of-life” in Part IV of the Homo Sacer is developed from his reflections upon Foucault, which suggests that Foucault's aesthetics of existence does not attain what he expects because of its association with tekhne or power. Therefore, Agamben critically inherits Foucault's thought from an ontological …

Study A Relationship Between Age, Body Mass Index, And Sperm Parameters With Sperm Dna Fragmentation Levels In Iraqi Infertile Patients, Talal Z. Al-Darawsha, Nurten Dayioglu, Bushra R. Al-Azzawi, Tulay Irez

Al-Ameed Journal for Medical Research and Health Sciences

Background: Male infertility is complex and accounts for approximately 50% of couples facing conception challenges. Factors such as body mass index, age, and sperm parameters play significant roles. Recognizing their impact is vital for diagnosis and treatment. Aim of the study: The study aimed to evaluate DNA integrity in individuals with unexplained infertility and assess its correlation with age, body mass index, and semen parameters. Materials and Methods: In this study, 111 males who met the inclusion criteria were recruited for our study. Selected participants were grouped according to their age, body mass index, and semen parameters, including (sperm count, …

Testosterone Hormone ; Clinical Indications, Dysregulation And Therapeutic Methods, Talal Z. Al-Darawsha

Al-Ameed Journal for Medical Research and Health Sciences

Testosterone is a hormone primarily produced by the testicles in adult men and it is the basic male sex hormone and an anabolic steroid. Androgen is important for survival. It is influences a man's appearance and sexual development, stimulating sperm production and regulating sex drive. This hormone is a key growth factor in prostate gland. Prostatic cells stop thriving when testosterone levels fall and Prostate cancer cells shrink both benign and malignant. Testosterone deficiency is a clinical and biochemical syndrome that is linked to ageing and is characterized by typical symptoms and a testosterone deficiency in the blood. The number …

E-Ethics, 2003 January, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a discussion of cultural barriers to organ donation and examines awareness, religion, racism, and other concerns.

E-Ethics, 2003 April, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a discussion on organizational ethics.

E-Ethics, 2003 May, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a discussion on confidentiality and filming patients.

E-Ethics, 2003 June, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a discussion of the new mandatory compliance of HIPAA on April 14, 2003.

E-Ethics, 2003 July, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a case study and discussion on ethical and safety concerns when discharging elderly patients.

E-Ethics, 2003 August, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has case studies and a discussion around consent, permission, and assent in pediatric research.

E-Ethics, 2003 September, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a case study and discussion around accepting non-traditional gifts from vendors.

E-Ethics, 2003 October, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a discussion on business decisions and favoritism.

E-Ethics, 2002 January, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a case study and discussion about respecting patients' spiritual practices during end-of-life care.

E-Ethics, 2002 February, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a discussion on the usefulness of a code of ethics.

E-Ethics, 2002 March, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a case study and discussion about providing compassionate and culturally sensitive care to Buddhist patients.

E-Ethics, 2002 April, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a discussion on patient safety and difference in severity between mistakes and errors in care.

E-Ethics, 2002 May, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a discussion on sex-selective abortions within differing social, cultural, and religious backgrounds.

E-Ethics, 2002 June, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "e-Ethics", a publication from The Park Ridge Center for the Study of Health, Faith and Ethics, associated with Lutheran General Hospital. This issue has a discussion on hospital culture and the disconnect between staff and patients.