Digital Commons Network^™

Comprehensive Review Merec Weighting Method For Smart Building Selection For New Capital Using Neutrosophic Theory, Asmaa Elsayed

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Sets And Systems, Vol. 63,2024, Florentin Smarandache, Mohamed Abdel-Basset, Said Broumi

Neutrosophic Sets and Systems

No abstract provided.

January 18, 2024, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Real-World Dispensing Of Buprenorphine In California During Prepandemic And Pandemic Periods, Yun Wang, Alexandre Chan, Richard Beuttler, Marc L. Fleming, Todd Schneberk, Michael Nichol, Haibing Lu

Pharmacy Faculty Articles and Research

Introduction: The opioid overdose crisis in the United States has become a significant national emergency. Buprenorphine, a primary medication for individuals coping with opioid use disorder (OUD), presents promising pharmacokinetic properties for use in primary care settings, and is often delivered as a take-home therapy. The COVID-19 pandemic exacerbated the scarcity of access to buprenorphine, leading to dire consequences for those with OUD. Most existing studies, primarily focused on the immediate aftermath of the COVID-19 outbreak, highlight the challenges in accessing medications for opioid use disorder (MOUDs), particularly buprenorphine. However, these studies only cover a relatively short timeframe. Methods: To …

X-Chromosome And Kidney Function: Evidence From A Multi-Trait Genetic Analysis Of 908,697 Individuals Reveals Sex-Specific And Sex-Differential Findings In Genes Regulated By Androgen Response Elements, Markus Scholz, Katrin Horn, Janne Pott, Matthias Wuttke, Andreas Kühnapfel, M. Kamal Nasr, Holger Kirsten, Yong Li, Anselm Hoppmann, Mikko Kuokkanen

School of Medicine Publications

X-chromosomal genetic variants are understudied but can yield valuable insights into sexually dimorphic human traits and diseases. We performed a sex-stratified cross-ancestry X-chromosome-wide association meta-analysis of seven kidney-related traits (n = 908,697), identifying 23 loci genome-wide significantly associated with two of the traits: 7 for uric acid and 16 for estimated glomerular filtration rate (eGFR), including four novel eGFR loci containing the functionally plausible prioritized genes ACSL4, CLDN2, TSPAN6 and the female-specific DRP2. Further, we identified five novel sex-interactions, comprising male-specific effects at FAM9B and AR/EDA2R, and three sex-differential findings with larger genetic effect sizes …

Identification Of Molecular Subphenotypes In Two Cohorts Of Paediatric Ards, Nadir Yehya, Matt S Zinter, Jill M Thompson, Michelle J Lim, Mark R Hanudel, Mustafa F Alkhouli, Hector Wong, Matthew N Alder, Daniel J Mckeone, E Scott Halstead, Pratik Sinha, Anil Sapru

2020-Current year OA Pubs

BACKGROUND: Two subphenotypes of acute respiratory distress syndrome (ARDS), hypoinflammatory and hyperinflammatory, have been reported in adults and in a single paediatric cohort. The relevance of these subphenotypes in paediatrics requires further investigation. We aimed to identify subphenotypes in two large observational cohorts of paediatric ARDS and assess their congruence with prior descriptions.

METHODS: We performed latent class analysis (LCA) separately on two cohorts using biomarkers as inputs. Subphenotypes were compared on clinical characteristics and outcomes. Finally, we assessed overlap with adult cohorts using parsimonious classifiers.

FINDINGS: In two cohorts from the Children's Hospital of Philadelphia (n=333) and from a …

Evaluation Of Seven Satellite-Based And Two Reanalysis Global Terrestrial Evapotranspiration Products, Zijing Xie, Yunjun Yao, Qingxin Tang, Meng Liu, Joshua B. Fisher, Jiquan Chen, Xiaotong Zhang, Kun Jia, Yufu Li, Ke Shang, Bo Jiang, Junming Yang, Ruiyang Yu, Xueyi Zhang, Xiaozheng Guo, Lu Liu, Jing Ning, Jiahui Fan, Lilin Zhang

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Although comprehensive evaluation of different types of global terrestrial evapotranspiration (ET) products has been conducted, the satellite remote sensing techniques have prompted the development of several available global ET products, warranting a reassessment as products continue to evolve. Recently, we produced the long-term Global LAnd Surface Satellite (GLASS) ET product, but there is a lack of comparison and evaluation with other ET products and EC observations on a global scale. In this study, we evaluated the accuracy and uncertainty of seven satellite-based (GLASS-AVHRR, GLASS-MODIS, BESS, FLUXCOM, GLEAM, MOD16, and PML_V2) and two reanalysis (ERA5 and MERRA2) global terrestrial ET products …

Deficit Irrigation Of Pastures, Matt Yost, Clara Anderson, Niel Allen, Burdette Barker, Melanie Heaton, Justin Wyatt Clawson, Earl Creech

All Current Publications

Deficit irrigation is any irrigation level that does not meet the crop’s full evapotranspiration (ET) demand, meaning evaporation from plant and soil surface and transpiration through plant growth. This strategy is often a last resort for optimizing water use as opposed to those that will not limit production. However, deficit irrigation is often necessary in parts of Utah due to drought or inadequate water supplies. This was especially true in 2021–2022 due to record droughts. Deficit irrigation strategies for pastures have been developed, but they have yet to be compared and evaluated in Utah. This fact sheet summarizes 6 years …

Predicting Radiotherapy Patient Outcomes With Real-Time Clinical Data Using Mathematical Modelling, Alexander P Browning, Thomas D Lewin, Ruth E Baker, Philip K Maini, Eduardo G Moros, Helen M Byrne

Faculty, Staff and Student Publications

Longitudinal tumour volume data from head-and-neck cancer patients show that tumours of comparable pre-treatment size and stage may respond very differently to the same radiotherapy fractionation protocol. Mathematical models are often proposed to predict treatment outcome in this context, and have the potential to guide clinical decision-making and inform personalised fractionation protocols. Hindering effective use of models in this context is the sparsity of clinical measurements juxtaposed with the model complexity required to produce the full range of possible patient responses. In this work, we present a compartment model of tumour volume and tumour composition, which, despite relative simplicity, is …

Complementary And Integrative Health Information In The Literature: Its Lexicon And Named Entity Recognition, Huixue Zhou, Robin Austin, Sheng-Chieh Lu, Greg Marc Silverman, Yuqi Zhou, Hua Xu

Faculty, Staff and Student Publications

Objective: To construct an exhaustive Complementary and Integrative Health (CIH) Lexicon (CIHLex) to help better represent the often underrepresented physical and psychological CIH approaches in standard terminologies, and to also apply state-of-the-art natural language processing (NLP) techniques to help recognize them in the biomedical literature.

Materials and methods: We constructed the CIHLex by integrating various resources, compiling and integrating data from biomedical literature and relevant sources of knowledge. The Lexicon encompasses 724 unique concepts with 885 corresponding unique terms. We matched these concepts to the Unified Medical Language System (UMLS), and we developed and utilized BERT models comparing their efficiency …

Polygenic Scores For Tobacco Use Provide Insights Into Systemic Health Risks In A Diverse Ehr-Linked Biobank In Los Angeles, Vidhya Venkateswaran, Kristin Boulier, Yi Ding, Ruth Johnson, Arjun Bhattacharya

Faculty, Staff and Student Publications

Tobacco use is a major risk factor for many diseases and is heavily influenced by environmental factors with significant underlying genetic contributions. Here, we evaluated the predictive performance, risk stratification, and potential systemic health effects of tobacco use disorder (TUD) predisposing germline variants using a European- ancestry-derived polygenic score (PGS) in 24,202 participants from the multi-ancestry, hospital-based UCLA ATLAS biobank. Among genetically inferred ancestry groups (GIAs), TUD-PGS was significantly associated with TUD in European American (EA) (OR: 1.20, CI: [1.16, 1.24]), Hispanic/Latin American (HL) (OR:1.19, CI: [1.11, 1.28]), and East Asian American (EAA) (OR: 1.18, CI: [1.06, 1.31]) GIAs but …

Alternative Dosing Regimen Of Exemestane In A Randomized Presurgical Trial: The Role Of Obesity In Biomarker Modulation, Harriet Johansson, Aliana Guerrieri-Gonzaga, Sara Gandini, Bjørn-Erik Bertelsen, Debora Macis, Gunnar Mellgren, Parijatham S Thomas, Katherine D Crew, Nagi B Kumar, Irene Maria Briata, Viviana Galimberti, Giuseppe Viale, Lana A Vornik, Valentina Aristarco, Tania Buttiron Webber, Stefano Spinaci, Powel H Brown, Brandy M Heckman-Stoddard, Eva Szabo, Bernardo Bonanni, Andrea Decensi

Faculty, Staff and Student Publications

In a 3-arm presurgical trial, four-six weeks exemestane 25 mg three times/week (TIW) was non-inferior to 25 mg/day (QD) in suppressing circulating estradiol in postmenopausal women with ER-positive breast cancer. Since obesity may decrease exemestane efficacy, we analyzed changes in sex steroids, adipokines, Ki-67, and drug levels in relation to obesity. Postmenopausal women with early-stage ER-positive breast cancer were randomized to either exemestane 25 mg QD (n = 57), 25 mg TIW (n = 57), or 25 mg/week (QW, n = 62) for 4-6 weeks before breast surgery. Serum and tissue pre- and post-treatment biomarkers were stratified by body mass …

Syphilis Complicating Pregnancy And Congenital Syphilis, Irene A Stafford, Kimberly A Workowski, Laura H Bachmann

Faculty, Staff and Student Publications

No abstract provided.

Maestros Of Anesthesia

Faculty, Staff and Student Publications

Microglia regulate anesthesia by altering the activity of neurons in specific regions of the brain via a purinergic receptor.

Enabling The Clinical Application Of Artificial Intelligence In Genomics: A Perspective Of The Amia Genomics And Translational Bioinformatics Workgroup, Robert R Freimuth, David B Everman, Derek C Walton, Scott P Mcgrath, Dominick J Lemas, Panayiotis V Benos, Alexander V Alekseyenko, Qianqian Song, Ece Gamsiz Uzun, Casey Overby Taylor, Alper Uzun, Thomas Nate Person, Nadav Rappoport, Zhongming Zhao, Marc S Williams

Faculty, Staff and Student Publications

OBJECTIVE: Given the importance AI in genomics and its potential impact on human health, the American Medical Informatics Association-Genomics and Translational Biomedical Informatics (GenTBI) Workgroup developed this assessment of factors that can further enable the clinical application of AI in this space.

PROCESS: A list of relevant factors was developed through GenTBI workgroup discussions in multiple in-person and online meetings, along with review of pertinent publications. This list was then summarized and reviewed to achieve consensus among the group members.

CONCLUSIONS: Substantial informatics research and development are needed to fully realize the clinical potential of such technologies. The development of …

Beyond Teaching: The Self-Fulfillment Of Creating A Positive And Safe Learning Environment For Children Exposed To Aces, Tessa J. Davis

The Journal of Advancing Education Practice

Due to factors such as burnout, lack of support, heavy workload, and student behavior, teachers are exiting the field for other occupations. Retention has become an issue. However, teachers are finding a sense of value and self-fulfillment for the same reasons they are leaving, which restores their outlook. This opinion paper will focus on teachers finding value in creating a positive learning environment in the classroom and creating resilience for students exposed to adverse childhood experiences at home.

Vol. 60 No. 4 - Whole No. 407, Megan Abrahamson

Mythprint

Mythprint is the quarterly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local discussion groups.

Booklet Of Sermon Notes For 1942-1943, Earl Clement Davis

Sermons, 1933-1953

For the years 1938 through 1947 Davis collected his sermon notes in more-or-less annual hand-bound booklets. This Booklet contained sermons for two years, 1942 and 1943, 101 different sermon notes in total.

The transcription of these notes have been separated into two shorter—although still long—documents, the first with the notes for sermons given during 1942 and the second for notes given during 1943. The primary document available for download is the full scan of the booklet itself. Supplemental downloads include the two transcription files, and the two sermon list documents for 1942 and 1943, respectively.

Transcription by Davis Baird. Item …

Jaipuria Institute Of Management, Lucknow Organizes Winter School - 2023 On Developing Competencies

Management Dynamics

No abstract provided.

Studying Adherence To Reporting Standards In Kinesiology: A Post-Publication Peer Review Brief Report, Nikki M. Watson, Jafra D. Thomas

International Journal of Exercise Science

International Journal of Exercise Science 17(7): 25-37, 2024. To demonstrate how post-publication peer reviews—using journal article reporting standards—could improve the design and write-up of kinesiology research, the authors performed a post-publication peer review on one systematic literature review published in 2020. Two raters (1^st & 2^nd authors) critically appraised the case article between April and May 2021. The latest Journal Article Reporting Standards by the American Psychological Association relevant to the review were used: i.e., Table 1 (quantitative research standards) and Table 9 (research synthesis standards). A standard fully met was deemed satisfactory. Per Krippendorff’s alpha-coefficient, inter-rater agreement …

The Relationship Between Athlete Perceptions Of Coaching Leadership Behaviors And Athlete Grit, Landon Braun, Lindsay Ross-Stewart, Barbara B. Meyer

International Journal of Exercise Science

International Journal of Exercise Science 17(5): 12-23, 2023. Coach leadership style has long been positively correlated with athlete experiences such as motivation, health (i.e., burnout), and performance outcomes (i.e., enhanced execution time to complete tasks) (24). More recently, grit (18) has been positively correlated with athlete experiences such as engagement (39) and decreased burnout (32). Given the impact coaches have on their athletes and the positive psychological benefits of grit, it is reasonable to explore the intersections of coaching behaviors and grit. As such, the purpose of the current study was to examine the relationship between athlete perceptions of coach …

Physical Fitness Responses After Sixteen Weeks Of Three Fitness Program Trainings In Untrained Subjects, Habil Hamdouni, Brian Kliszczewicz, Hassane Zouhal, Abderraouf Ben Abderrahman

International Journal of Exercise Science

International Journal of Exercise Science 17(4): 54 - 72, 2024. The remarkable popularity of fitness trends like high intensity functional training (HIFT), choreographed high intensity classes (CHIC) and resistance (RT) trainings raises the question on their effect on cardio-respiratory, lactate removal rate, endurance and body composition responses. The purpose of this study was to assess and compare these effects. Ninety-five participants were randomly assigned into 16 weeks of these trainings, five sessions/week. Anthropometric and fitness tests were carried out before training (PRE), after eight (8W) and sixteen weeks (16W). Body composition measures demonstrated significant decrease in body fat percentage ( …

Ida Polk

African American Funeral Programs

No abstract provided.

Hattie Beola Postell

African American Funeral Programs

No abstract provided.

Evaluation Of The Craniovertebral Angle In Standing Versus Sitting Positions In Young Adults With And Without Severe Forward Head Posture, David A. Titcomb, Bridget F. Melton, Helen W. Bland, Theresa Miyashita

International Journal of Exercise Science

International Journal of Exercise Science 17(1): 73-85, 2024. The purpose of this study was to examine the effects of standing versus sitting body position on the craniovertebral angle (CVA) in young adults without pathology; and to investigate whether mean differences between positional CVA measures in subjects with severe forward head posture (FHP) are distinct from age-matched controls with normal head posture. Ninety-eight young adults (68 women, 30 men) without pathology (OVERALL; n = 98) volunteered for the study; those with CVA > 53° were also included in a normal posture group (NORM; n = 14); those with CVA < 45° were also included in a severe FHP group (SEV; n = 15). …

Bench Press Range-Of-Motion And Velocity-Based Repetition Control: Effects On Ballistic Push-Up Performance In Males, Kyle Collins, Adam Bradley, Bryan Christensen, Roman Waldera, Lukus Klawitter, Liam Ogren, Robert Salatto

International Journal of Exercise Science

International Journal of Exercise Science 17(1): 38-53, 2024. The purpose of this study was to investigate whether the ballistic push-up (BPU) is responsive to post-activation performance enhancement (PAPE) after a bench press conditioning exercise using velocity-based repetition control. Additionally, we aimed to evaluate the effects of range of motion (ROM) conditions on subsequent BPU performance. In a randomized crossover design, 18 males performed two conditions (full ROM and self-selected partial ROM) of bench press at 80% of their 1RM until mean concentric velocity dropped 10%. Each participant performed two pre- and six post-test BPUs to assess the PAPE effect. Paired …

Homeownership And Mortgage Loans: How Important Is A Conventional Loan?, Zachary Owen, Cory Curl

Posters-at-the-Capitol

Communities across the United States face a housing crisis that stems in part from a scarcity of conventional home mortgage loans. In 2020, the Urban Institute reported that when applying for a mortgage, Black applicants were denied 27.1% of the time, yet White applicants were denied only 13.6% of the time. These denial rates are highly correlated with homeownership rates. Today, despite policy efforts, the difference in White and Black homeownership rates is higher than in the 1960s when the government enforced discriminatory housing policy.

Because lenders often cite credit score concerns and high debt-to-income ratios as rationales to deny …

Global Criminal Justice Practices And Public Safety, Rachel Hwang

Posters-at-the-Capitol

Popular political discourse in the U.S. assumes that more funding for law enforcement and prison facilities will make civilians safer, presumably by reducing crime and sense of disorder. However, studies have shown that the relationship between these factors may not be as straightforward. With the killing of George Floyd and increased media coverage of police brutality, existing literature focuses mainly on the relationship between police and crime in the U.S. The impact of incarceration (the result of procedural justice) on the community (for whom procedural justice exists) is less known, especially on a global scale. We argue that cycling people …

Enhancing The Safety Of Medication Administration: The Synergistic Role Of Closed Loop Electronic Medication Management And Iv Medication Administration, Kelly Goetz, Angela Schoenung, Lauren Daugherty, Kaitlyn Hornsby

Posters-at-the-Capitol

The high acuity of patients in the ICU results in numerous medications being administered, increasing the risk of medication errors. The purpose of this project is to investigate the impact of integrating consistent closed loop electronic medication management (CLEMM) to decrease medication errors in the ICU for bedside nurses who use electronic health records (EHRs). The project type is a comprehensive literature review, with studies that included a single prospective cohort study, case report, single non-randomized trial, quasi experimental study, single cross-sectional studies, and systematic reviews. The importance of this project is to address the break in the loop of …

Securing Edge Computing: A Hierarchical Iot Service Framework, Sajan Poudel, Nishar Miya, Rasib Khan

Posters-at-the-Capitol

Title: Securing Edge Computing: A Hierarchical IoT Service Framework

Authors: Nishar Miya, Sajan Poudel, Faculty Advisor: Rasib Khan, Ph.D.

Department: School of Computing and Analytics, College of Informatics, Northern Kentucky University

Abstract:

Edge computing, a paradigm shift in data processing, faces a critical challenge: ensuring security in a landscape marked by decentralization, distributed nodes, and a myriad of devices. These factors make traditional security measures inadequate, as they cannot effectively address the unique vulnerabilities of edge environments. Our research introduces a hierarchical framework that excels in securing IoT-based edge services against these inherent risks.

Our secure by design approach prioritizes …