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Articles 16711 - 16740 of 2913339
Full-Text Articles in Entire DC Network
Concept Analysis In Occupational Therapy Research: Exploring Approaches And Discipline-Specific Considerations, Patricia Schofield, Tanja Krizaj, Kirsty Thomas
Concept Analysis In Occupational Therapy Research: Exploring Approaches And Discipline-Specific Considerations, Patricia Schofield, Tanja Krizaj, Kirsty Thomas
School of Nursing and Midwifery
PurposeThis paper aims to explore the use and considerations needed for conducting a concept analysis within occupational therapy research. Concept analysis is a popular analytical research tool used with the methodology providing firmer definitions of ambiguous concepts.Design/methodology/approachAn exploration into the use of concept analysis within occupational therapy research. Discussing current approaches of concept analysis and the implementation of this within occupational therapy research.FindingsConcept analysis within occupational therapy research requires further consideration. Current research is favouring one approach when completing a concept analysis that leads to common flaws within the methodology.Originality/valueFurther consideration is required to the approaches followed when completing a …
Dental Educators' Perceptions Of Factors Contributing To Their Well‐Being—A Qualitative Study, M. Powell, Y. Howell, S. Anishchuk, S. Bhatia
Dental Educators' Perceptions Of Factors Contributing To Their Well‐Being—A Qualitative Study, M. Powell, Y. Howell, S. Anishchuk, S. Bhatia
Peninsula Dental School
BackgroundStress levels within academic institutions are high and have continued to rise over recent decades. This can have a detrimental impact on the well-being of dental educators and puts them at a risk of burnout. It is vital to explore the factors that affect the well-being of staff and identify solutions to inform the development of strategies for the promotion of well-being.MethodsParticipants attending the ADEE annual conference were invited to participate in a qualitative study using focus group discussions to explore this topic. Prompts for the four focus group discussions were identified from quantitative data collected in an earlier study …
Screen-Based Simulation Assessment For Emergency Medicine Learners: A Rapid Review, Patrick Zeniecki, Rebecca Kamens, Jared Kilpatrick, Dimitrios Papanagnou, Xiao C. Zhang
Screen-Based Simulation Assessment For Emergency Medicine Learners: A Rapid Review, Patrick Zeniecki, Rebecca Kamens, Jared Kilpatrick, Dimitrios Papanagnou, Xiao C. Zhang
Department of Emergency Medicine Faculty Papers
BACKGROUND: Simulation has played a vital role in training medical professionals. The COVID-19 Pandemic has highlighted the need for physically distant educational assessment methods. Screen-based simulation (SBS) demonstrates one alternative to traditional in-person simulation methods to assess learners clinical reasoning and communication skills. This study aims to compare in-person simulation to SBS as assessment methods in Emergency Medicine (EM).
METHODS: A rapid review literature search methodology of an electronic database (PubMed) was performed in February 2022 with search terms such as "Computer Simulation," "Patient Simulation," "Simulation Training," "Education, Distance," "Virtual OSCE," "Academic Performance," or "Emergency Medicine." Reference lists of relevant …
Autoregulation Of Three Yeast Ribosomal Protein Genes By Splicing Inhibition, David Granas, Anirudh Kesanapally, Michael A White, Gary D Stormo
Autoregulation Of Three Yeast Ribosomal Protein Genes By Splicing Inhibition, David Granas, Anirudh Kesanapally, Michael A White, Gary D Stormo
2020-Current year OA Pubs
Yeast ribosomal protein genes RPL18B, RPL28, and RPS22B are autoregulated by inhibition of splicing. This is demonstrated by inserting their introns into a chromosomal copy of GFP and observing repression upon induction of the cognate protein. In RPL18B and RPS22B, a predicted conserved secondary structure within the intron is required for regulation, while in RPL28, it is not.
The Relationship Between Psychological Stress And Sars-Cov-2 Nucleocapsid-Antibody Response Following Natural Infection: Longitudinal Findings From The Aegis Study, Erika T Beidelman, Ashley Judge, David B Allison, Stephanie Dickinson, Lilian Golzarri Arroyo, Anna L M Macagno, Michael J Ricciardi, Jon Macy, Stanley Perlman, Christina Ludema, Kevin C Maki, Molly Rosenberg
The Relationship Between Psychological Stress And Sars-Cov-2 Nucleocapsid-Antibody Response Following Natural Infection: Longitudinal Findings From The Aegis Study, Erika T Beidelman, Ashley Judge, David B Allison, Stephanie Dickinson, Lilian Golzarri Arroyo, Anna L M Macagno, Michael J Ricciardi, Jon Macy, Stanley Perlman, Christina Ludema, Kevin C Maki, Molly Rosenberg
Faculty, Staff and Students Publications
Psychological stress can cause diminished immune response to infectious challenges. The extent this holds true during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the modifying effect of vaccination status is untested. We explored these relationships in a non-random sample standardized to the US adult population. Across 2178 participants in the Aegis study (2021-2022), we identified 507 eligible laboratory-confirmed SARS-CoV-2 infections. We estimated the natural log of nucleocapsid-binding antibody absorbance (N-antibody) at study visits up to 225 days following a positive SARS-CoV-2 test. Linear mixed effects models were fit to estimate the association of baseline perceived stress and, separately, …
Complement Activation In Maternal And Placental Pathology Of Preeclampsia, Manu T Banadakoppa, Madhulatha S Chauhan, Moises J Tacam, Allyson W Nevins, Antonio H Ruano, Simone H Ruano, Jon A Fuson, Chandra Yallampalli
Complement Activation In Maternal And Placental Pathology Of Preeclampsia, Manu T Banadakoppa, Madhulatha S Chauhan, Moises J Tacam, Allyson W Nevins, Antonio H Ruano, Simone H Ruano, Jon A Fuson, Chandra Yallampalli
Faculty, Staff and Students Publications
Background: Preeclampsia is a multifactorial, pregnancy-related disorder characterized by new-onset hypertension and proteinuria, with distinct early- and late-onset forms. Although complement dysregulation has been implicated in the pathogenesis of preeclampsia, its causal role remains unclear. In mice, Crry (complement receptor 1-related protein Y) functions as a critical complement regulator at the fetal-maternal interface. Because complete Crry deficiency is embryonically lethal, direct in vivo investigation of complement activation in pregnancy has been challenging.
Methods: We generated a placenta-specific, doxycycline-inducible short hairpin RNA mouse model in which Crry expression can be downregulated in a dose-dependent manner. This system employs Cyp19-driven Cre recombinase …
Cytosine Base Editing Of Lpa In Transgenic Mice Averts Large Deletions, Marcel A Chuecos, So Hyun Park, Madhvi M Bhakta, Usosa Too-Chiobi, Daniel Betancourth, Mingming Cao, Marco De Giorgi, Christopher J Walkey, Anjana Tiwari, Biana Godin, Julia M Assini, Donna J Palmer, Philip Ng, Michael B Boffa, Marlys L Koschinsky, Gang Bao, William R Lagor
Cytosine Base Editing Of Lpa In Transgenic Mice Averts Large Deletions, Marcel A Chuecos, So Hyun Park, Madhvi M Bhakta, Usosa Too-Chiobi, Daniel Betancourth, Mingming Cao, Marco De Giorgi, Christopher J Walkey, Anjana Tiwari, Biana Godin, Julia M Assini, Donna J Palmer, Philip Ng, Michael B Boffa, Marlys L Koschinsky, Gang Bao, William R Lagor
Faculty, Staff and Students Publications
Lipoprotein(a) (Lp(a)) is a genetically determined causal risk factor for cardiovascular disease, with approximately 20% of the population exhibiting elevated levels. While there are promising drugs in development, there are currently no approved therapies specifically designed to lower Lp(a) levels. For high-risk individuals with extreme levels of Lp(a), liver-directed genome editing could be an effective one-time solution. Genome editing approaches such as CRISPR and TALENs can reduce Lp(a) in LPA-transgenic mouse models, but they frequently induce large and potentially harmful genomic deletions. Here, we report the first application of TadA-derived cytosine base editing (CBE), delivered via helper-dependent adenovirus (HDAdV) and …
Transgenic Hookworm Secretes Anti-Tetrodotoxin Human Single Chain Antibody, Kumar Sachin Singh, Suman Bharti, Bruce A Rosa, Mahdiyeh Bigham, Samuel C Uzoechi, Young-Jun Choi, John C Martin, Danielle Kemper, Slavica Pavlovic Djuranovic, Sergej Djuranovic, Makedonka Mitreva, Et Al.
Transgenic Hookworm Secretes Anti-Tetrodotoxin Human Single Chain Antibody, Kumar Sachin Singh, Suman Bharti, Bruce A Rosa, Mahdiyeh Bigham, Samuel C Uzoechi, Young-Jun Choi, John C Martin, Danielle Kemper, Slavica Pavlovic Djuranovic, Sergej Djuranovic, Makedonka Mitreva, Et Al.
2020-Current year OA Pubs
Biologics, protein- and peptide-based drugs derived from living organisms or cell lines have emerged as effective therapies across a broad range of indications. However, parenteral administration and the need for frequent dosing increase costs and limit compliance, creating an urgent need for innovative platforms capable of continuously, safely, and efficiently delivering sustained biologics in situ within the host. Here, we describe a bioengineered hookworm platform to manufacture and deliver biologic therapeutics in vivo. As proof of concept, we engineer the Ancylostoma ceylanicum secretome by inserting a human single-chain variable fragment antibody (s16-HuScFv) into its genome. Transgene expression does not perturb …
A Comprehensive Survey Of Artificial Intelligence Applications In Predicting Mining-Induced Subsidence, Deformation, And Landslides: Strengths, Limitations, And Future Trends, Long Quoc Nguyen, Dung Ba Nguyen, Minh Tuyet Dang
A Comprehensive Survey Of Artificial Intelligence Applications In Predicting Mining-Induced Subsidence, Deformation, And Landslides: Strengths, Limitations, And Future Trends, Long Quoc Nguyen, Dung Ba Nguyen, Minh Tuyet Dang
Journal of Sustainable Mining
Mining activities often cause mining-induced ground deformation, including subsidence and landslides, and related geo-environmental impacts, posing significant risks to infrastructure and safety. This study conducts a systematic assessment to identify, categorize, and evaluate AI-based methods (machine learning, deep learning, and hybrid models) for predicting and monitoring mining-induced ground deformation. The literature search was performed across major scientific databases, using predefined keywords and selection criteria, resulting in a final dataset of relevant peer-reviewed studies. The reviewed works were classified into three methodological groups: traditional machine learning, deep learning-based approaches, and hybrid methods. The results show that ML still dominates in terms …
Napier Grass (Pennisetum Purpureum) Meal Modulates Growth Efficiency, Gut Morphology, And Systemic Health In Broiler Chickens, Eric Lim Teik Chung, Yee Lyn Ong, Nazri Nayan, Muhamad Faris Ab Aziz, Faez Firdaus Abdullah Jesse, Faizal Andri, Arissara Sopawong
Napier Grass (Pennisetum Purpureum) Meal Modulates Growth Efficiency, Gut Morphology, And Systemic Health In Broiler Chickens, Eric Lim Teik Chung, Yee Lyn Ong, Nazri Nayan, Muhamad Faris Ab Aziz, Faez Firdaus Abdullah Jesse, Faizal Andri, Arissara Sopawong
The Thai Journal of Veterinary Medicine
Grass and leaf meals, which include vital phytocompounds, have the potential to be a natural and safe alternative to antibiotics in the poultry industry. Therefore, this study aims to assess Pennisetum purpureum leaf meal and its phytocompounds on the health performances of colored-broilers. A total of 216 unsexed Sasso chicks were assigned to six diet groups. The negative control (T1) received a commercial basal diet without antibiotics, while the positive control (T2) received the same diet with oxytetracycline (100 mg/kg). Groups T3 to T6 received no antibiotics and included P. purpureum meal at 1.25, 2.50, 3.75, or 5.00 grams per …
You Must Be This Tall To Scroll: California's Questionable Approach To Parenting By Policy, Caroline M. Cuddy
You Must Be This Tall To Scroll: California's Questionable Approach To Parenting By Policy, Caroline M. Cuddy
Pace Law Review
This note examines California's Protecting Our Kids from Social Media Addiction Act (SB 976), signed into law in September 2024, which prohibits personalized algorithmic feeds on minors' accounts without pa- rental consent and restricts platform notifications during school hours and nighttime. Drawing on the Supreme Court's decision in Brown v. Entertainment Merchants Association and related federal litigation, this note argues that SB 976 is unconstitutional under the First Amendment. Specifically, SB 976 is underinclusive because it fails to meaning- fully reduce minors' screen time, exempts comparable addictive plat- forms, and permits the very algorithmic feeds it deems harmful upon parental …
Chipping Away At Stone: Rethinking The Establishment Clause After Kennedy, Christian Edmonds
Chipping Away At Stone: Rethinking The Establishment Clause After Kennedy, Christian Edmonds
Pace Law Review
In Kennedy v. Bremerton School District, the Supreme Court abandoned the Lemon test and replaced it with a framework grounded in historical practices and understandings. Yet lower courts have struggled to operationalize that standard, and some have continued to rely on Stone v. Graham, a brief 1980 per curiam opinion rooted entirely in Lemon, as controlling precedent. This Article argues that Stone cannot survive Kennedy’s wholesale repudiation of Lemon and its progeny. Using the Fifth Circuit’s decision in Roake v. Brumley, which struck down Louisiana’s Ten Commandments display law on the basis of Stone, as a case study, the Article …
Blurred Lines: Did Booker Change Federal Sentencing Outcomes?, Hugh M. Mundy
Blurred Lines: Did Booker Change Federal Sentencing Outcomes?, Hugh M. Mundy
Pace Law Review
This article considers whether United States v. Booker, the 2005 Supreme Court decision that replaced the then-mandatory federal sentencing guidelines system with an advisory scheme, had any enduring impact on sentencing outcomes. Commemorating Booker’s recent twentieth anniversary requires a balancing act: at once, recognizing the decision’s watershed impact while avoiding claims of lasting change where little exists. The criminal defense community hailed the ruling as a kind of liberation from the guidelines’ dispassionate rigidity. Today, while most lawyers and defendants would still prefer the current system, a legitimate question exists about Booker’s actual effect on federal sentencing. I propose that …
The Constitutionality Of The Special Trial Counsel Under The Apogee Of Judicial Deference, Josef Danczuk
The Constitutionality Of The Special Trial Counsel Under The Apogee Of Judicial Deference, Josef Danczuk
Pace Law Review
Congress has undertaken some of its broadest reforms of military courts-martial in decades. The creation of the Special Trial Counsels (STCs) intentionally removes nearly all courts-martial powers from military commanders for “covered offenses,” some of the most serious prosecutions. Many commentators have expressed concern that this change untethers the courts-martial system from its historical anchor of discipline within the military—an anchor that the Supreme Court has used to grant exceptional deference to Congress for its legislation pursuant to the Make Rules Clause. However, the constitutionality of the STCs and the deference federal courts grant Congress in this realm should not …
Daydreaming: How Far Can We Go?, Abigail Toribio
Managing Editor Statement 2026, Cody Roberts
Letter From The Editors, Writing Waves Editors
Editorial, Joseph P. Hupy, Mary M. Fink
Editorial, Joseph P. Hupy, Mary M. Fink
Journal of Aviation Technology and Engineering
Editorial for JATE 14.1.
Glory, North Dakota State University--Fargo
Glory, North Dakota State University--Fargo
Promotional Material and Program
It’s Women’s Hockey meets A League of Their Own! Set in the Great Depression of the 1930’s, this highly engaging and humorous tale follows the journey of four women who set out to form one of the most iconic women’s hockey teams in history. Told with music and dance inspired from the jazz age, GLORY follows the true story of Canada’s own Preston Rivulettes – the pioneering Women’s Hockey Team that fought to play the game they loved, and to prove that hockey isn’t just a sport for men. This inspiring and thrilling play is the feel good story …
The Trauma Challenge: Are You Ready To Lead With Trust-Based Relational Intervention?, Tara Quinn-Schuldt Dr., Patrick Walker, Melinda Meadow, Megan Jance
The Trauma Challenge: Are You Ready To Lead With Trust-Based Relational Intervention?, Tara Quinn-Schuldt Dr., Patrick Walker, Melinda Meadow, Megan Jance
Southeast Conference on School Climate
In today’s educational landscape, understanding trauma isn’t optional, it’s essential. The Cherokee County School District has transformed from trauma-aware to trauma-responsive through intentional implementation and the creation of its connectED cohort training model. Combining strategic district-wide staff, including administrators, teachers, school support personnel, nurses, and resource officers—we created a collective approach to improving school climate, culture, and overall student outcomes. This comprehensive model integrates mental health, attachment theory, behavior intervention, and trauma responsiveness into the educational environment. This session shares evidence-based tools, a trauma-responsiveness assessment template, and strategies to address contradictions and strengthen trauma-responsive practices.
Glory, North Dakota State University--Fargo
Glory, North Dakota State University--Fargo
Dramaturgy
It’s Women’s Hockey meets A League of Their Own! Set in the Great Depression of the 1930’s, this highly engaging and humorous tale follows the journey of four women who set out to form one of the most iconic women’s hockey teams in history. Told with music and dance inspired from the jazz age, GLORY follows the true story of Canada’s own Preston Rivulettes – the pioneering Women’s Hockey Team that fought to play the game they loved, and to prove that hockey isn’t just a sport for men. This inspiring and thrilling play is the feel good story …
The War For American Independence Was Biblical And Just*, Mark David Hall
The War For American Independence Was Biblical And Just*, Mark David Hall
Journal of Law and Government
In his essay, Mark David Hall presents an overview of Christian scholarship on the question of whether the War for American Independence is biblical and just. He then considers Romans 13 and shows that Protestants, especially Calvinists, came to interpret these verses to permit active resistance to tyrannical rulers. Finally, he discusses the conflict in light of the just war tradition and contends that the patriots had excellent reasons to believe their active resistance was biblical and just.
Was The American Revolution Biblical And/Or Just?, Gregg L. Frazer
Was The American Revolution Biblical And/Or Just?, Gregg L. Frazer
Journal of Law and Government
The questions of whether the American Revolution was biblical and whether it was just may be necessarily intertwined. If it was biblical, then it was just. If it was unbiblical, it was necessarily unjust. If it was merely non-biblical, that is, if the Bible does not speak to the question, then it could be either just or unjust by some human standard. For the purposes of this paper, the question of whether it was just by a merely human standard will be addressed independently of, and in addition to, the infinitely more important question of whether it is biblical. We …
Bridging Covenant And Efficiency: A Mixed-Methods Exploration Of Faith-Based Environmental Nonprofits Under New Public Management Reform, Jacob Berry
Journal of Law and Government
This paper explores covenantal environmental administration as a significant framework for contemporary public governance within faith-based environmental nonprofits (FENs). As New Public Management (NPM) reforms increasingly shape nonprofit administration through efficiency and performance metrics, covenantal governance emerges as an alternative rooted in mutual obligation, ethical leadership, and spiritual stewardship, concepts deeply embedded in Judeo-Christian traditions exemplified by loving fulfillment. Contrary to perceptions of incompatibility between ethical-spiritual values and data-driven accountability, this study argues that integrating covenantalism with New Public Management practices can enhance organizational performance, stakeholder trust, and ecological outcomes. Employing theoretical analysis and empirical tools (notably the Covenantal Empowerment …
Introducing The Covenantal-Noncentralization Index (Cni) For Assessing Localism, Social Capital, Community Challenges And Community Health, Kahlib Fischer, Edwin Christmann, Melissa Stewart, Todd Robatin, Zachary Federico, John Kebles, Lucy Lambert, Alex Mishra
Introducing The Covenantal-Noncentralization Index (Cni) For Assessing Localism, Social Capital, Community Challenges And Community Health, Kahlib Fischer, Edwin Christmann, Melissa Stewart, Todd Robatin, Zachary Federico, John Kebles, Lucy Lambert, Alex Mishra
Journal of Law and Government
Numerous indices measuring social capital and community challenges at the local level exist, but none attempt to offer a measure of community health as an independent variable in comparison to community challenges as a dependent variable. Therefore, we propose the Covenantal-Noncentralization Index (CNI) in an effort to provide a more nuanced understanding of social capital at the local level as well as to differentiate between an independent variable index consisting of family stability, religious adherence, non-profit activity, and charitable giving and dependent variables representing various community challenges: violent crime, childhood poverty, STD rate, high school diploma completion, GDP, and unemployment. …
Defending The West By Reclaiming The Past, Steven Alan Samson
Defending The West By Reclaiming The Past, Steven Alan Samson
Journal of Law and Government
The Western world was originally shaped by the fine arts and philosophy of Greece, the architecture and law of Rome, and the faith, morality, and prophetic traditions of Judaism and Christianity. As the West loses the religious bond that generated its culture, careful attention should be given to reclaiming and rebuilding this moral and spiritual infrastructure.
Letter From The Editor, Kahlib Fischer
Letter From The Editor, Kahlib Fischer
Journal of Law and Government
No abstract provided.
Letter From The Dean, Jason Bohm
The Plight Of “Unreasonable” Trafficking Victims: A Critical Assessment Of The Trafficking Victims Protection Act’S “Reasonable Person” Standard For Coercion In Policy-Oriented Perspective, Christian L. Gonzalez Rivera
The Plight Of “Unreasonable” Trafficking Victims: A Critical Assessment Of The Trafficking Victims Protection Act’S “Reasonable Person” Standard For Coercion In Policy-Oriented Perspective, Christian L. Gonzalez Rivera
Social Justice & Equity Law Journal (Willamette University College of Law)
Since the enactment of the Trafficking Victims Protection Act of 2000 and its requirement that, in alleging trafficking by means of coercion, victims and prosecutors make a showing that the victim was coerced under a reasonable person standard, an entire class of victims effectively became disenfranchised and no longer deemed victims. The inability to meet such a high burden of proof produces not only the lack of successful criminal and civil prosecutions, but also – and most alarmingly – precludes many a victim’s participation in basic and highly needed government services, required both to cope with and recover from the …