Digital Commons Network^™

Mental Health Stigma In Latin American Youth With Obsessive-Compulsive Disorder, Ryan J Mccarty, Matias Jensen, Elissa Paz Jensen Santa Cruz, Melisa N Sagarnaga, Pamela Claisse Quiroz, Tomás Miño, Paola Giusti-Rodriguez, Mayra C Martinez Mallen, Maria B Moyano, Dayan Berrones, Jacey L Anderberg, Renee M Frederick, Hannah C Moore, Josselyn S Muñoz, Vanessa Zavala Cruz, Latin American Trans-Ancestry Initiative For Ocd Genomics (Latino), Brazilian Obsessive-Compulsive Spectrum Working Group (Gttoc), Ogechi C Onyeka, Andrew D Wiese, James J Crowley, Eric A Storch

Faculty, Staff and Students Publications

Obsessive-compulsive disorder (OCD) is an impairing mental health condition that affects individuals across the lifespan. Some literature has evaluated mental health stigma in adults with OCD but limited attention has been given to youth, as well as those of Latino ancestry. The present study reported the extent of stigma experiences among Latin American youth with OCD, as well as examined sociodemographic, clinical and psychological correlates. 235 youth with clinician confirmed diagnoses of OCD from 10 North and South American countries completed questionnaires assessing stigma experiences, symptomatology, and functioning. Sociodemographic and clinical variables were also collected. The average OCD stigma response …

Evidence-Based Classification Of Genes Implicated In Skeletal Disorders Using The Clingen Curation Framework, Ryan F Webb, Hannah Mccurry, Amanda Girod, Madeline Hughes, Emma Wilcox, Mayher Patel, Eleanor C Broeren, Kezang C Tshering, Marina Distefano, Lorenzo D Botto, Lindsay C Burrage, Valérie Cormier-Daire, Juan Dong, Nadja Ehmke, Deborah Krakow, Shahida Moosa, Geert Mortier, Sandesh Nagamani, Loren Pena, Pedro A Sanchez-Lara, Andrea Superti-Furga, Sheila Unger, Danita Velasco, Matthew L Warman, Kerry Brown, Deepika D'Cunha Burkardt, Carlos R Ferreira

Faculty, Staff and Students Publications

More than 770 genetic skeletal disorders have been described, most with disease-causing variants reported in 1 of over 550 different genes. The ClinGen Skeletal Disorders Gene Curation Expert Panel was established to determine the strength of the evidence that supports specific gene-disease relationships (GDRs). Such information can assist clinical testing laboratories in choosing genes that should be included on diagnostic panels. Nine genes accounting for the most frequently encountered skeletal dysplasias (COL1A1, COL1A2, COL2A1, FGFR3, SLC26A2, TRPV4, COMP, ALPL, and SOX9) associated in the medical literature with 26 different skeletal disorders were reviewed using a semi-quantitative scoring framework. This framework …

Jak Inhibition In Pnpt1-Related Mitochondrial Interferonopathy: A Case Report And Review Of Mitochondrial-Immune Crosstalk, Dan Ross Brooks, Hyun Yong Koh, Taylor Martin Kerrins, Steven Lang, Emily Bland, Rui Yang, Sarah Kogan Nicholas, Stephanie Jean Sikkink, Stephen Kralik, Christine Eng, Chaya Nautiyal Murali, Seema Lalani, Pilar Lenglet Magoulas, Lisa Emrick, Kristen Sydney Fisher, Fernando Scaglia

Faculty, Staff and Students Publications

Biallelic pathogenic variants in PNPT1 cause combined oxidative phosphorylation deficiency 13 (COXPD13) (MIM #614932), linking mitochondrial dysfunction to type I interferon (IFN) activation through cytosolic leakage of mitochondrial double‐stranded RNA (mt‐dsRNA). This mechanism connects mitochondrial disease to interferonopathies such as Aicardi–Goutières syndrome (AGS). We describe a 7‐month‐old female infant with compound heterozygous PNPT1 variants presenting with severe hypotonia, feeding difficulties necessitating gastrostomy, dystonia, and elevated serum lactate. Brain magnetic resonance imaging (MRI) demonstrated marked cerebellar, brainstem, and basal ganglia atrophy, with a lactate peak on MR spectroscopy (consistent with an inverted doublet). Serum immune profiling revealed a mild but elevated …

Biphasic Sleep Is A Feature Of Sleep Disturbance In Syngap1-Rd, Aida Doucoure, Het Patel, Mark A Abboud, Alice Sperry, Sarah K Wanigatunga, Deana Crocetti, Heather Volk, Adam P Spira, Stewart H Mostofsky, Vaishnav Krishnan, Constance Smith-Hicks

Faculty, Staff and Students Publications

Study objectives: Sleep problems are common in children with SYNGAP1-Related Disorder (SYNGAP1-RD). The use of devices that objectively estimate sleep are complicated by co-occurring sensory disorders in this population. We examined the feasibility and validity of wrist actigraphy to examine sleep and rest-activity rhythms (RAR).

Methods: Data from five children with SYNGAP1-RD and 42 typically developing children were analyzed. All children were asked to wear the Actiwatch-2 for 14 continuous days and caregivers were asked to complete a sleep diary and the Children Sleep Health Questionnaire (CSHQ). Parametric (alpha, beta, acrophase, amplitude, up/down mesor, mesor), nonparametric (intradaily variability, interdaily stability, …

Statistical Evaluation Of A New Orleans Historic Rainfall Dataset (1840–1893), Arielle C. Filostrat

LSU Master's Theses

This study evaluates the climatic credibility of a newly identified historical rainfall dataset for New Orleans, Louisiana, spanning 1840–1893. The New Orleans Historical Dataset (NOHD) is compared to a modern observational record from the Audubon rain gauge (1893–2024) to determine whether nineteenth-century rainfall observations are consistent with known precipitation behavior in the region. Establishing the reliability of early records is critical for extending climatological baselines and improving understanding of long-term rainfall variability.

Historical rainfall observations were first evaluated through archival review using the New Orleans Medical and Surgical Journal and other nineteenth-century meteorological records to verify notable rainfall events. Daily …

Nuclear-Specific Reductive Carboxylation Of Alpha-Ketoglutarate Fuels Histone Acetylation To Induce Chromatin Accessibility And Gene Activation, Abhisha Sawant Dessai, Nadya A Elhalawany, Tao Dai, Justine J Jacobi, Christian Prechtl, Alphonse N Dimeck, Sierra R Morton, Mark D Long, Prashant K Singh, Nagireddy Putluri, Mariana Lopes, Song Liu, Dominic J Smiraglia, Katerina V Gurova, Peder J Lund, Leah A Gates, Sung Yun Jung, Subhamoy Dasgupta

Faculty, Staff and Students Publications

Mitochondria remain at the core of cell metabolism, whereas the nucleus integrates cellular and environmental signals to activate genes. However, the mechanisms that directly link cellular metabolism to gene regulation are not well understood. Here we show, a metabolic pathway in the nucleus controls acetylation of histones by nuclear localization of mitochondrial enzymes aconitase (ACO2) and isocitrate dehydrogenase (IDH2). Metabolic tracing studies show that IDH2 and ACO2 catalyze reductive carboxylation of α-ketoglutarate to rapidly synthesize citrate to increase nuclear acetyl-CoA pool. Genetic and proteomic analyses reveal nuclear IDH2 and ACO2 form a complex with KAT2A/GCN5 for acetylation of histones to …

Human Exposure To Spirochete-Infected Ornithodoros Turicata In A Residential Setting In The Austin, Texas Metropolitan Area, Serhii Filatov, Bonny Mayes, Sarah M Gunter, Alexander R Kneubehl, Job E Lopez

Faculty, Staff and Students Publications

A central Texas resident found an engorged Ornithodoros turicata tick attached to their ankle while at home. The tick tested positive for Borrelia turicatae, an agent for soft tick-borne relapsing fever. Three weeks earlier, the patient started experiencing febrile episodes, rash, and nausea, yet the etiological agent went undiagnosed.

Homework Adherence In Exposure-Based Cbt For Youth With Obsessive-Compulsive Disorder: Clinical Outcomes And Predictors Across Treatment, Abigail E Pine, Qimin Liu, Eric A Storch, Daniel A Geller, Brent J Small, Sabine Wilhelm, Joseph F Mcguire

Faculty, Staff and Students Publications

Exposure-based cognitive behavioral therapy (CBT) is the frontline treatment for pediatric obsessive-compulsive disorder (OCD), but not all youth fully respond to this treatment. While multiple factors may influence CBT response, homework adherence in CBT is a modifiable target that can improve treatment outcomes. This report examines the relationship between homework adherence and clinical outcomes in a large sample of youth with OCD who received exposure-based CBT. Here, 137 youth with OCD between 7 and 17 years old (M = 12.42, SD = 2.88) participated in a randomized controlled trial of exposure-based CBT. Homework adherence was monitored weekly, and OCD severity …

A Call To Investigate The Association Between Histoplasmosis And Fatigue, Christian Hendrix, Julio Zuniga-Moya, Andrej Spec, Patrick Mazi

2020-Current year OA Pubs

Historically, infections are subjectively associated with fatigue, a common yet poorly delineated syndrome. The impact on patient quality of life is the ultimate justification to evaluate fatigue in patients with infections. While fungal infections are subjectively associated with fatigue, there are minimal quantifiable fungal research outcomes that evaluate histoplasmosis and fatigue.

The Unexpected Role Of Conditionality In Shaping Relational Values: Insights From An Incentive-Based Conservation Program In Bolivia, Brooke Mcwherter, Will Munger, Zhao Ma, Claudia Radel, Laura Zanotti, Jonathan Bauchet, Ricardo Godoy

Department of Agricultural Economics Faculty Publications

As global change accelerates, Payments for Ecosystem Services (PES) programs have become increasingly important tools for addressing the interconnected challenges of land degradation, biodiversity loss, water scarcity, and climate change. PES programs provide incentives to individuals or communities, conditional on people adopting sustainable natural resource management practices to support or increase ecosystem service provisioning. Although conditionality is considered a “PES-defining feature,” little is known about how conditionality is perceived by community members and how such perceptions influence their participation in and experience with PES programs. To address this gap, we conducted an extensive qualitative study of Watershared, an incentive-based conservation …

Amplifying Change For Adolescent Girls In West And Central Africa Through Economic Empowerment, Mame Soukeye Mbaye, Sarah Engebretsen, Maty Dia, Karen Austrian

Adolescents and Young People

The Girls’ Futures in Focus: Evidence from West and Central Africa series examines the challenges facing adolescent girls in the region and highlights evidence-informed approaches to improving their lives. This brief summarizes the evidence on adolescent girls’ economic empowerment—income, livelihoods, savings, financial inclusion, agency, transition to work, or all of the above—in West and Central Africa, drawing in particular on evidence from the GIRL Center’s priority countries. The brief points to what shifts adolescent girls’ economic trajectories in the region, especially in fragile and low-resource settings.

Understanding The Lubrication Mechanisms Of Environmentally Compatible Protic Ionic Liquids, Davis Kipkania Kiboi

Theses

The development of environmentally sustainable lubricants is increasingly important as industries seek to reduce friction, wear, energy losses, and environmental impact. Choline amino acid protic ionic liquids (PILs) have emerged as promising candidates due to their bio-based constituents, tunable molecular structures, and favorable lubrication properties. However, the influence of amino acid structure on their lubrication mechanisms and tribological performance remains poorly understood. This dissertation investigates the physicochemical properties, tribological behavior, and tribofilm formation mechanisms of choline amino acid PILs to establish structure–property–performance relationships for sustainable lubricant design. Ten choline amino acid PILs containing glycine, alanine, lysine, leucine, isoleucine, aspartic acid, …

Video Games As An Advertising Media: A Comparative Analysis Between Portuguese And Spanish University Students, Alejandro Tapia-Frade, Gema Bonales-Daimiel, Belén Moreno-Albarracín

Faculty Research, Scholarly, and Creative Activity

Changes in leisure consumption are causing transformations in the relationships between young people and brands. A reflection of this is found in video games, whose predominant user profile is that of young people between 18 and 30 years old. They invest more and more time in digital universes: they play, socialize and even buy, and income from the video game sector has increased year after year in Spain and in the world, surpassing those generated jointly by cinema and music. A review of previous literature indicates the relevance as an object of study of video games that are used as …

Incidence And Outcomes Of Treatment-Associated Hepatotoxicity During Pediatric Acute Lymphoblastic Leukemia Induction Therapy: A Reducing Ethnic Disparities In Acute Leukemia (Redial) Consortium Report, Ashley N Chavana, Emily J Mason, John P Woodhouse, Olga A Taylor, Monica M Gramatges, Joanna S Yi, Sandi Pruitt, M Brooke Bernhardt, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Marley Roberts, Rodrigo Erana, Juan Carlos Bernini, Hong Zhu, Philip J Lupo, Karen R Rabin, Michael E Scheurer, Steven D Mittelman, Van Huynh, Etan Orgel, Austin L Brown

Faculty, Staff and Students Publications

No abstract provided.

Mechanisms Coordinating Exit From The Stem Cell State In Mammals, Emily J Park, Florencia Levin-Ferreyra, Bruno Di Stefano

Faculty, Staff and Students Publications

Differentiation requires coordinated exit from the stem cell state, during which gene regulatory networks sustaining self-renewal are dismantled, while lineage-specific programs are activated. This transition is governed by chromatin modifications, transcriptional networks, RNA processing, translational control, and metabolic rewiring that must operate with temporal precision. Despite significant progress in identifying individual regulatory components, understanding how these layers integrate to orchestrate irreversible cell fate commitment remains a fundamental challenge. This review examines common and unique regulatory principles governing stem cell exit, from totipotency during early embryogenesis to tissue-specific stem cell differentiation in adults. We synthesize recent findings on regulatory mechanisms across …

The Impact Of Alexithymia On Body Image: The Mediating Role Of Rumination Among Students At Sultan Qaboos University, Fatima Alrahbi, Mai Helmy, Amal Alhadabi

Journal of Educational and Psychological Studies

The study aimed to examine the mediating role of rumination in the relationship between the dimensions of alexithymia and body image among first-year students at Sultan Qaboos University in the Sultanate of Oman. The descriptive method was employed, and the sample consisted of 310 male and female first-year students at Sultan Qaboos University, who were selected using a convenience sampling method. The study instruments included three scales: the Body Image Scale, the Toronto Alexithymia Scale, and the Rumination Scale. The results indicated the presence of statistically significant direct effects of the dimensions of alexithymia on rumination. The findings showed that …

Mindfulness And Its Relationship To Cognitive Flexibility Among University Students, Nafez Ahmad Abed Bukaiei, Adnan Mahmoud Hassan Odeh

Journal of Educational and Psychological Studies

This study aims to examine the relation between mindfulness and cognitive flexibility among university students. It also aimed to identify the level of mindfulness and the level of cognitive flexibility based the variables of gender, grade point average, and school year level. To achieve the aims of this study, the descriptive correlational approach was adopted through the use of the mindfulness scale of Bear & Others (2006) which was translated into Arabic by Al-Buhairi et al. (2014) and the cognitive flexibility scale of Dennis & Vander Wal (2010) which was translated by the researchers. The sample group consisted of 185 …

The Machiavellian Personality And Its Relationship With Research Self-Efficacy Among Graduate Students, Zuhair Abdul Hamid El-Nawajha

Journal of Educational and Psychological Studies

The research aimed to identify the level of Machiavellian personality and research self-efficacy, as well as the correlation between them. It also sought to reveal the differences in Machiavellian personality and research self-efficacy according to the variables of gender and academic degree.The researcher used the descriptive correlational approach. The research sample consisted of 103 male and female graduate students, from universities in the Gaza Strip. To achieve the research objectives, the researcher used the Machiavellian Personality Scale, prepared by (Dahling et al., 2009), and developed the Research Self-Efficacy Scale.The results of the study showed that the level of Machiavellian personality …

The Degree Of Inclusion Of 21st Century Skills In The 12th Grade Geography Curriculum From The Perspective Of Teachers In The State Of Kuwait And Its Relationship To Their Teaching Performance, Huda Salem Alazmi

Journal of Educational and Psychological Studies

The present study aimed to identify the degree of inclusion of 21st-century skills in the 12th-grade geography curriculum from the perspective of teachers in public education in the State of Kuwait, and to examine its relationship to their teaching performance. The study adopted a descriptive correlational approach. A questionnaire was used to identify the degree of inclusion of 21st-century skills in the geography curriculum, while an observation checklist was employed to assess teachers› teaching performance. The questionnaire was administered to a random sample of 327 geography teachers in secondary public schools in Kuwait. Additionally, 38 observation checklists were applied to …

Understanding The Forest School Experience: A Conceptual Exploration Of Benefits And Barriers, Ziad F. Dabaja

Journal of Educational and Psychological Studies

Forest School, a form of outdoor nature-based education, has increasingly gained international attention, particularly, its educational and developmental benefits are well documented. While existing literature highlights positive outcomes for children, families, and educators, it also identifies a range of challenges that can hinder effective implementation. This paper adopts a conceptual study design and synthesizes findings from three peer-reviewed literature reviews, collectively examining 40 international studies, to develop an integrative concept map of the Forest School experience. Using a thematic synthesis, evidence from the reviewed studies was analyzed to identify overlapping and complementary themes, which were categorized into benefits, implementation challenges, …

Using The Consolidated Framework For Implementation Research (Cfir) To Evaluate Complex School Settings, Carlie P. Coerver, Tricia A Zucker

Summer Research Program Abstracts

No abstract provided.

Long-Term Quality Of Life For Patients With Merkel Cell Carcinoma Receiving Standard-Of-Care Adjuvant Radiation Therapy, Christian Paul D. Denolan, Kelsey N. Nordlund, Aya F. Salem, Devarati Mitra

Summer Research Program Abstracts

No abstract provided.

Caregiver Health Literacy Is Associated With Pediatric Burn Recovery Outcomes, Ananya Sampathkumar, Anna Sabukurian, Erin M. Morris, Alyssa M. Griffith, Nicholas A. Long, Alexa Cumming, Macie Boden, Christina G. Morris, Lauren K. Mayon, Thian H. Nguyen, Allison L. Speer, Natalie A. Drucker

Summer Research Program Abstracts

No abstract provided.

Sex Differences In Surveillance Outcomes Of Thoracic Aortic Disease: Insights From The “Watchful Waiting” Study, Trang H. Do, Brian Shukwit, Minjae Lee, Siddharth K. Prakash

Summer Research Program Abstracts

No abstract provided.

Understanding Delays In Human Milk Fortification Timing And Impact On Growth Outcomes In Very Low Birthweight Preterm Infants, Maria Poblete, Sepideh Saroukhani, Manouchehr Hessabi Md, Mph, Amirali Tahanan Ms, Lindsay F Holzapfel

Summer Research Program Abstracts

No abstract provided.

Cryptic Habits: The Hidden Lives Of Midsouth Entomologists. Interview With Dr. Jerome Goddard, Mississippi Public Health Entomologist And Fiction Novelist, C. J. Peterson, Jerome Goddard

Midsouth Entomologist

No abstract provided.

Subspace Decomposition For Spatial Parameter Estimation, Arthur Grik

USF Tampa Graduate Theses and Dissertations

Passive emitter localization is an important capability for wireless sensing, interference detection, and spectrum awareness. Classical timing-based localization methods estimate emitter position from differences in signal arrival time across distributed sensor platforms, but their performance depends on precise receiver synchronization and favorable signal bandwidth characteristics. This thesis investigates subspace-decomposition-based spatial parameter estimation as an alternative approach in which directional information is extracted from coherent antenna-array measurements. This work develops the theoretical foundation and signal-processing framework for angle-of-arrival estimation. Various spatial parameter estimators are presented as supporting array-processing methods before focusing on a well-known subspace-decomposition-based approach called the Multiple SIgnal Classification …

Evaluating Special Education Teachers’ Competence In Inclusive Education: A Study Of Behavior Management, Level Of Confidence, And Training Needs, Kourtney Guthrie

Electronic Theses and Dissertations

The purpose of this mixed-methods study is to examine the competence of special education teachers in rural East Texas, focusing on their experiences, perceptions, and professional development needs related to behavior management and inclusive education. Quantitative data were gathered through questionnaires given to special education teachers and elaborated upon through focus group interviews, where themes emerged. An explanatory sequential mixed-methods design was used to develop a better understanding of teachers’ preparedness and the problems involved in the implementation of inclusive practices. The findings may inform more effective teacher training, policy-making, and support systems in rural educational settings by highlighting professional …

Long-Term Outcomes And Symptom Response Following Hypofractionated Stereotactic Radiotherapy For Intracranial Meningioma, Ryan Shah, Bs, Nilanjan Haldar, Shray Jain, Lauren Holt, Sophia Shah, Hamail Iqbal, Anthony Chen, Christopher J. Farrell, Debanjan Haldar, James J. Evans, Gregory S. Alexander, Wenyin Shi

Department of Neurology Faculty Papers

Objective: Various radiation dosing regimens exist due to tumor size, location, and patient preference. This study evaluated the long-term outcomes of patients with benign meningiomas treated with hypofractionated stereotactic radiotherapy (SRT)at our institution.

Methods: This is a retrospective review of all patients diagnosed with meningioma at our institution who received hypofractionated SRT (5 fractions). Clinical data, including tumor location, size, prior treatments, demographics, radiation dosimetric information, tumor response, and survival were collected. Kaplan-Meier curves were used to assess local control (LC). Acute and late toxicities were evaluated. Patients were included for analysis if they had at least one post-treatment magnetic …

Perceptions Of Research Participation Among Underrepresented Groups: Insights Using Freelisting Methodology, Tamar Klaiman, Jasmine Silvestri, Emma Britez Ferrante, Dorothy Sheu, Adina Lieberman, Erich Dress, Modele Ogunniyi, Neal Dickert, Meghan Lane-Fall, Rosemary Frasso, Rachel Kohn

College of Population Health Faculty Papers

BACKGROUND: Low enrollment and retention in clinical research disproportionately impact Black, Hispanic or Latinx, women, and rural populations, undermining generalizability and perpetuating health disparities. However, few studies have compared mechanisms driving underrepresentation across populations. Freelisting is a qualitative methodology that elicits lists of terms, explores perspectives about domains, and identifies common themes within groups with shared characteristics; however, it has not been systematically applied to understand research participation across underrepresented populations.

OBJECTIVE: To explore perspectives on clinical research participation across underrepresented populations using freelisting methodology to ultimately inform culturally-responsive recruitment strategies.

METHODS: We conducted a web-based freelisting survey among adults …