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Articles 11041 - 11070 of 2913340
Full-Text Articles in Entire DC Network
Racial Profiling In Traffic Enforcement: A Qualitative Exploration Of Police Chiefs' Perspectives On Traffic Stop Data Analysis, Peter J. Didomenica
Racial Profiling In Traffic Enforcement: A Qualitative Exploration Of Police Chiefs' Perspectives On Traffic Stop Data Analysis, Peter J. Didomenica
Walden Dissertations and Doctoral Studies
Racial profiling of people of color by police departments as part of traffic enforcement practices is a pervasive practice in the United States. The practice is a form of systemic racism, the conceptual framework for this study, that has resulted in people and communities of color suffering its deleterious effects. Although statistical analysis of traffic stop data is most effective in uncovering racial profiling in traffic enforcement, most police departments fail to conduct such analysis, and for those departments that do so, there is no uniform judicially accepted method. The purpose of this study was to understand the reasons most …
Nt 415 3rd Ave Llc V. Gharibian
Nt 415 3rd Ave Llc V. Gharibian
All Decisions
In this non-primary residence holdover proceeding involving a rent-stabilized unit, landlord moved for discovery of records relevant to tenants' primary residence and succession claims. The court granted the motion in part, applying the presumption of liberal disclosure in housing court proceedings and finding that the requested discovery was relevant to the pending non-primary residence and succession issues.
The Stigma Experiences Of The African American Transgender Individual In Mental Health Settings, Linda Shaw Henley
The Stigma Experiences Of The African American Transgender Individual In Mental Health Settings, Linda Shaw Henley
Walden Dissertations and Doctoral Studies
The intersection of race, gender identity, and systemic marginalization has profound implications for mental health outcomes, particularly among African American transgender individuals. Addressing African American transgender individuals’ stigma experiences in mental health settings is important because transgender individuals have dual minority statuses, wherein racism, stigma, transphobia, and institutional neglect converge, significantly impacting their access to affirming and effective mental health treatment. The purpose of this study was to explore the stigma experiences of the African American transgender individual in mental health settings. The phenomenon of interest in this study was stigma experiences in mental health settings with mental health providers. …
Longitudinal Genomic Surveillance Of Sars-Cov-2 In A University Microcosm Reflects Global Evolutionary Trends, Sankar Prasad Chaki, Melissa M Kahl-Mcdonagh, Benjamin W Neuman, Loni A Taylor, Rebecca S B Fischer, Blake M Hanson, Marlisa S Hardy, Jo Ann Culpepper, Eric Boerwinkle, Kurt A Zuelke
Longitudinal Genomic Surveillance Of Sars-Cov-2 In A University Microcosm Reflects Global Evolutionary Trends, Sankar Prasad Chaki, Melissa M Kahl-Mcdonagh, Benjamin W Neuman, Loni A Taylor, Rebecca S B Fischer, Blake M Hanson, Marlisa S Hardy, Jo Ann Culpepper, Eric Boerwinkle, Kurt A Zuelke
Faculty, Staff and Student Publications
SARS-CoV-2 transmission has declined, yet ongoing viral evolution continues to pose public health challenges. This study conducted long-term (2020-2024) genomic surveillance within a large and globally diverse university community. Viral genomes obtained from clinical (n = 1,786) and surveillance (n = 888) testing samples were classified under clade, lineage, and variant systems, and compared with global genomic data sets. Local patterns broadly paralleled global evolutionary trends, including the phased emergence of major variants, episodic introductions of new lineages, and shifts in dominant clades. Lineage diversity peaked during fall semesters and was highest among undergraduate-aged individuals, with similar distributions …
Implementation Of A Follow-Up Call To Improve Glp-1 Medication Compliance, Hanna Weitzman-Flanigan
Implementation Of A Follow-Up Call To Improve Glp-1 Medication Compliance, Hanna Weitzman-Flanigan
DNP and Student Works
Background: Obesity is a major driver of healthcare spending in the United States. GLP-1 receptor agonists are effective for weight management; however, high rates of early discontinuation reduce both clinical and economic value.
Methods: A pre–post quality improvement project implemented a nurse-led follow-up call at four weeks.
Results: Adherence improved significantly (p=0.009), weight decreased by 10 pounds (p=0.023), and estimated annual savings per patient were $6,472, contingent on sustained long-term adherence. Total estimated project savings were $80,141.
Conclusion: Nurse-led follow-up calls are a high-value intervention supporting economic sustainability.
Security Architecture Decision Framework For Endpoint Protection In Resource-Constrained K-12 Environments, Jason Folker
Security Architecture Decision Framework For Endpoint Protection In Resource-Constrained K-12 Environments, Jason Folker
Journal of Cybersecurity Education, Research and Practice
K-12 educational institutions face an ongoing challenge in protecting endpoints when budgets and staffing prevent the implementation of standard security best practices. Technology directors routinely make difficult decisions about administrative rights, software controls, and security tooling, but they lack frameworks designed for the constraints and priorities specific to educational environments. This paper develops a security architecture decision framework tailored for K-12 endpoint protection. The framework integrates five weighting dimensions to help technology directors evaluate competing architectural choices. These dimensions include educational impact, security risk reduction, resource requirements, compliance obligations, and operational feasibility. The framework creates structured documentation that helps decision-makers …
Coherent Two-Photon Backscattering And Induced Angular Quantum Correlations In Multiple-Scattered Two-Photon States Of The Light, Nooshin M. Estakhri, Theodore B. Norris
Coherent Two-Photon Backscattering And Induced Angular Quantum Correlations In Multiple-Scattered Two-Photon States Of The Light, Nooshin M. Estakhri, Theodore B. Norris
Engineering Faculty Articles and Research
We present the emergence of coherent two-photon backscattering, a manifestation of weak localization, in multiple scattering of maximally entangled pure and fully mixed two-photon states and examine the effect of entanglement and classical correlations. Quantum correlations in backscattering are investigated for finite three-dimensional disordered structures in the weak localization regime, as well as systems of a small number of scatterers with specified spatial arrangements. No assumptions are made about the statistical behavior of the scattering matrix elements. Furthermore, we study the interplay between quantum correlations induced by multiple scattering and the correlations that may be present in the illumination fields, …
Full Issue: Summer 2026
DePaul Magazine
In DePaul Magazine's summer 2026 issue, learn how DePaul is living its Vincentian mission through innovative community engagement and service learning, exemplified by its Irwin W. Steans Center and Speech Language Pathology and Occupational Therapy graduate programs. Also, meet alumna Kate Steinberg who revisits her youth and DePaul days as a rising social media influencer, get the latest news from DePaul's 10 colleges and schools, and much more.
Campaign Corner
DePaul Magazine
Learn more about DePaul's ambitious Mission: Forward philanthropic campaign, including its collaborative leadership structure, two landmark gifts benefiting the university's Catholic mission and School of Music, and an imminent, state-of-the-art basketball practice facility.
Millennial Memories
DePaul Magazine
Social media influencer Kate Steinberg (CMN '13), who studied public relations and advertising at DePaul, revisits her youth and DePaul days to create viral content with a nostalgic edge.
Educating School Nurses On Trauma-Informed Care, Na-Keisha Allene White
Educating School Nurses On Trauma-Informed Care, Na-Keisha Allene White
Walden Dissertations and Doctoral Studies
Trauma-informed care is a critical component of supporting students' overall wellness, and school nurses are central to this work. They are often the first professionals to recognize when a student is exhibiting a trauma response or experiencing a mental health concern during the school day. Although evidence-based school health organizations have advanced efforts to ensure that academic environments are prepared to support students’ mental health needs, school nurses are too often left out of these strategic planning processes. Their exclusion not only overlooks their clinical expertise but also weakens the school’s ability to respond effectively and holistically to student needs. …
Fecal Fatty Acids And Other Risk Factors Associated With Multiple Sclerosis Score, Progression And Diagnosis Among Hispanic Adults, Juliana Ayala-Viqueira
Fecal Fatty Acids And Other Risk Factors Associated With Multiple Sclerosis Score, Progression And Diagnosis Among Hispanic Adults, Juliana Ayala-Viqueira
Walden Dissertations and Doctoral Studies
Multiple sclerosis (MS) is a chronic neurological condition with insufficient research regarding risk factors influencing MS severity score (MSSS), progression and diagnosis among Hispanic adults living in the United States. This cross-sectional study assessed factors associated with MS score, progression and diagnosis using secondary data from the International Multiple Sclerosis Microbiome Study (iMSMS). Guided by the ecological model, the study included N = 576 participants with MS. Manuscript 1 explored the association between body mass index (BMI), sodium consumption, and the MS severity score in a Hispanic adult population. A multiple linear regression was conducted to examine whether age and …
Examining Inmate Labor In Emergency Management: Contributions, Challenges, And Ethical Considerations, Boris Eugene Valiance
Examining Inmate Labor In Emergency Management: Contributions, Challenges, And Ethical Considerations, Boris Eugene Valiance
Walden Dissertations and Doctoral Studies
Incarcerated individuals remain inconsistently engaged in disaster preparedness, response, and recovery, creating both an operational gap and an ethical challenge regarding labor equity, safety, voluntariness, and human dignity. Guided by RBT and EMT, the purpose of this qualitative case study was to explore how incarcerated individuals are utilized in emergency management and to examine stakeholder perceptions of the operational, ethical, and policy implications of inmate labor programs. The research questions examined current utilization patterns, stakeholder-perceived benefits and drawbacks, and ethical concerns influencing participation decisions. Data were collected through semi structured interviews with purposefully sampled emergency management professionals, policymakers, and correctional …
The Impact Of Social Determinants Of Health On Alcoholism Among African American Communities Aged 65 And Older, Kymberly Williams
The Impact Of Social Determinants Of Health On Alcoholism Among African American Communities Aged 65 And Older, Kymberly Williams
Walden Dissertations and Doctoral Studies
Alcohol use disorder among African American older adults (aged ≥65) remains an underrecognized contributor to preventable morbidity and diminished quality of life. Although previous research has identified individual risk factors for alcohol misuse, little is known about how social determinants of health shape alcohol use among this population. The purpose of this descriptive phenomenological study was to explore how family support, experiences of racial discrimination, religious engagement, and economic stability influence late-life alcohol use. Cultural Resilience Theory guided the exploration of how cultural resources and structural stressors influence alcohol use. Five African American adults aged 65 years and older were …
Relationship Between Employee Engagement, Gender, And Intention To Quit In The Retail Industry, Lataya V. Mills
Relationship Between Employee Engagement, Gender, And Intention To Quit In The Retail Industry, Lataya V. Mills
Walden Dissertations and Doctoral Studies
Intention to quit remains a significant challenge for retail organizations, contributing to recruitment and training costs, workforce instability, and operational disruptions. The purpose of this quantitative correlational research project was to examine the relationship between employee engagement, gender, and intention to quit among frontline retail employees in the Mid-Atlantic United States. Grounded in employee engagement theory, participants included 71 frontline retail employees. Data were collected using the Utrecht Work Engagement Scale, an Intention to Quit Scale, and demographic questions. Composite scores were calculated for employee engagement and intention to quit, and the data were analyzed using descriptive statistics, reliability analysis, …
Cytoskeletal Protein Expression In Autism Spectrum Disorder: A Psychoneuroimmunological Perspective On Sars-Cov-2, James Birch
Cytoskeletal Protein Expression In Autism Spectrum Disorder: A Psychoneuroimmunological Perspective On Sars-Cov-2, James Birch
Walden Dissertations and Doctoral Studies
The COVID-19 pandemic heightened concerns about health disparities among individuals with autism spectrum disorder (ASD). Limited understanding of the biological factors underlying health variability may hinder efforts to reduce disparities and improve care for neurodivergent populations. Guided by the psychoneuroimmunology framework, this quantitative study investigated whether cytoskeletal gene expression was associated with neuroimmune variability in ASD and SARS-CoV-2 populations. Three genes –Nck-associated protein 1 (NCKAP1), WAS/WASL-interacting protein family member 1 (WIPF1), and actin-related protein 2/3 complex subunit 1B (ARPC1B)—were evaluated using two publicly available Gene Expression Omnibus datasets GSE212645 (ASD vs. sibling-matched controls, N = 40) and GSE152641 (SARS-CoV-2-positive vs. …
Women Refugees & Immigrants: What Utahns Need To Know, Susan R. Madsen, Deborah Lin
Women Refugees & Immigrants: What Utahns Need To Know, Susan R. Madsen, Deborah Lin
Marketing and Strategy Faculty Publications
Refugee and immigrant women are an integral part of Utah’s communities, contributing as neighbors, workers, entrepreneurs, caregivers, and advocates. They enrich our state through their diverse perspectives, experiences, and talents. Utah has a long tradition of welcoming newcomers, and our communities are stronger when everyone has the opportunity to belong and contribute. At the same time, research shows that many of the challenges facing Utah women and girls disproportionately affect refugee and immigrant women. Understanding the experiences, needs, and contributions of these women is essential to fostering welcoming, supportive communities so that all Utah women and girls can thrive.
Examining The Moderating Roles Of Religious Coping And Belonging In The Relationship Between Moral Injury, Depression, Anxiety, And Stress Within The Israeli Defense Forces Reservist Soldiers, Rotem Z. Moshe
Electronic Theses and Dissertations 2020 - Present
This study examined the moderating roles of religious coping and belonging in the relationship between moral injury and psychological distress, among Israeli Defense Forces (IDF) reservist soldiers. This study investigated whether religious coping predicted moral injury, depression, anxiety, and stress, and examined whether religious coping and belonging moderated the relationship between moral injury and psychological distress. Exposure to potentially morally injurious events during military service is associated with increased risk for adverse mental health effects, particularly in times of prolonged conflict. Research on protective factors that mitigate these outcomes remains limited. Pointed by religious coping and belongingness frameworks, this study …
Constructing A Lower-Bound Estimate Of The Global Number Of Insect Species On A Hyperdiverse Empirical Foundation, Robert Colwell, Laura Melissa Guzman, Dirk Steinke, Anne Chao, Daniel H. Janzen, Winnie Hallwachs, Austin Baker, Jose L Fernández-Triana, Paul D.N. Hebert, Frank Joyce, Robert Puschendorf, Donald L.J. Quicke, Rodolphe Rougerie, M. Alex Smith, Nelson Zamora, Michael J. Sharkey
Constructing A Lower-Bound Estimate Of The Global Number Of Insect Species On A Hyperdiverse Empirical Foundation, Robert Colwell, Laura Melissa Guzman, Dirk Steinke, Anne Chao, Daniel H. Janzen, Winnie Hallwachs, Austin Baker, Jose L Fernández-Triana, Paul D.N. Hebert, Frank Joyce, Robert Puschendorf, Donald L.J. Quicke, Rodolphe Rougerie, M. Alex Smith, Nelson Zamora, Michael J. Sharkey
School of Biological and Marine Sciences
Estimating the number of insect species on Earth is a daunting challenge. The current consensus estimate—about six million species—is likely far too low, as we will show. Our estimate of the global number of insect species rests on a sample of more than 1,600,000 DNA-barcoded insect specimens representing 53,945 species from 15 “core” Malaise traps deployed in dry forest, cloud forest, and rainforest ecosystems of the Área de Conservación Guanacaste (ACG) in Costa Rica. Even this massive sample fails to reveal the full extent of ACG insect species richness. To estimate total ACG insect richness, we adjust the observed count …
Apala Best Of The Best Booklist 2025, Apala Best Of The Best Booklist 2023 - 2024 Authors Asian Pacific American Librarians Association, Family Literacy Focus Committee, Jessea Young (Co-Chair), Jennifer Woo, Nicole Fernandez, Erika Fitzpatrick, Alvina Lai, Cathy Lin, Patty Sumire Mcgowan, Kim Nguyen
Apala Best Of The Best Booklist 2025, Apala Best Of The Best Booklist 2023 - 2024 Authors Asian Pacific American Librarians Association, Family Literacy Focus Committee, Jessea Young (Co-Chair), Jennifer Woo, Nicole Fernandez, Erika Fitzpatrick, Alvina Lai, Cathy Lin, Patty Sumire Mcgowan, Kim Nguyen
Librarian Publications & Presentations
The Best of the Best Booklist celebrates stories from across the Asian American, Native Hawaiian, and Pacific Islander (AANHPI) diaspora. All APALA members were invited to nominate picture book titles about AANHPI communities and experiences that were published between September 1, 2024–August 31, 2025. The Family Literacy Focus Committee selected books aligned with the Talk Story mission and used the APALA Rubric for Evaluating Asian American and Pacific Islander Youth Literature to guide the curation of the list. Eligible titles that earned a 2025-2026 APALA Literature Award or Honoree designation have been included at the end of this list.
Serial Drilling Technique For Sequential Subtrochanteric Femur Fracture Fixation In Pediatric Osteopetrosis: A Technical Report., Adam Mansour, Josiah J Wolf, Ivan Slyepkan, Morgan Turnow, Michael Anderson, Anthony Wing, Jack Iandoli, Craig Goubeaux, Craig Smith, Allen Kadado
Serial Drilling Technique For Sequential Subtrochanteric Femur Fracture Fixation In Pediatric Osteopetrosis: A Technical Report., Adam Mansour, Josiah J Wolf, Ivan Slyepkan, Morgan Turnow, Michael Anderson, Anthony Wing, Jack Iandoli, Craig Goubeaux, Craig Smith, Allen Kadado
Surgery Articles
Pediatric osteopetrosis presents a significant technical challenge for fracture fixation due to the bone's dense yet brittle nature and frequently absent medullary canal. Traditional drilling methods risk excessive torque, drill-bit breakage, and iatrogenic fractures. Here, we describe a serial drilling technique for plate-and-screw fixation in a 5-year-old child with osteopetrosis who sustained sequential subtrochanteric femur fractures 8 months apart. By creating a small pilot hole, sequentially enlarging it with intermediate bits under copious irrigation, and inserting locking screws manually, we achieved stable fixation with no observed instrument failure or intraoperative complications. This method may provide a practical technical strategy for …
Beyond 72 Hours: A Retrospective Evaluation Of Factors Associated With Delayed Surgical Stabilization Of Rib Fractures., Alexis A Schweibinz, Clarisse Solis, Anna Michaud, John Dillis, Katherine A Graham, William B Devoe
Beyond 72 Hours: A Retrospective Evaluation Of Factors Associated With Delayed Surgical Stabilization Of Rib Fractures., Alexis A Schweibinz, Clarisse Solis, Anna Michaud, John Dillis, Katherine A Graham, William B Devoe
OhioHealth Research Institute Articles
BACKGROUND: Surgical stabilization of rib fractures (SSRF) is recognized as a key intervention in reducing morbidity among patients with multiple displaced rib fractures or flail chest. Early SSRF, typically within 72 hours of admission, has been associated with improved outcomes. The factors contributing to delayed stabilization, defined as 72 hours or greater following admission, remain unclear.
METHODS: A retrospective cohort study was performed, evaluating 492 trauma patients who underwent SSRF at a level II trauma center. Patient demographics, injury characteristics, and associated injuries were analyzed to identify factors associated with delayed SSRF. Groups were defined as early (≤72 hours) and …
Fostering Active Learning In Reproductive Health Classes Among Undergraduates Of A Nigerian Public University: The Role Of Cognitive Restructuring Health Education, Ndubuisi Friday Ugwu, Adewumi Segun Igbinlade, Adijat Bolanle Adams, Uchenna Anselm Anibueze, Gabriel Aderibigbe Oyegbami, Chinyere Chrysantus Onwurah, Sabina Nwakaego Igwilo, Olufemi M. Olubamise, Folasade Adediran, Oladipo Adeyeye Olubodun Phd, Jacob Kehinde Opele, Loveth Nnenna Ugwu, Amos Olorunwa Agbojo
Fostering Active Learning In Reproductive Health Classes Among Undergraduates Of A Nigerian Public University: The Role Of Cognitive Restructuring Health Education, Ndubuisi Friday Ugwu, Adewumi Segun Igbinlade, Adijat Bolanle Adams, Uchenna Anselm Anibueze, Gabriel Aderibigbe Oyegbami, Chinyere Chrysantus Onwurah, Sabina Nwakaego Igwilo, Olufemi M. Olubamise, Folasade Adediran, Oladipo Adeyeye Olubodun Phd, Jacob Kehinde Opele, Loveth Nnenna Ugwu, Amos Olorunwa Agbojo
Higher Learning Research Communications
Objective: This study examined the efficacy of the cognitive restructuring health education (CRHE) intervention in improving participatory learning in sexual and reproductive health classes among students at a Nigerian public university.
Methods: The study employed a randomized pretest/posttest control group design involving 130 undergraduates from Federal University Oye-Ekiti, Nigeria. Participants were randomly assigned to either a 2-week intensive health education–based cognitive restructuring program (n = 65) or a waitlist control group (n = 65). Interaction behavior was assessed at pretreatment, at post-treatment, and at a 6-week follow-up using the 14-item Interaction Behavior Checklist (reliability = 0.85). …
2026-07-07 Professor Removed Following Public Criticism Of Administration, Dylan Berman
2026-07-07 Professor Removed Following Public Criticism Of Administration, Dylan Berman
The Spectator Online
No abstract provided.
Tips For Growing Garden Vegetables In Utah: Soil Fertilization, Gastone Makalaya, Josh Martin, Milena Oliveira
Tips For Growing Garden Vegetables In Utah: Soil Fertilization, Gastone Makalaya, Josh Martin, Milena Oliveira
All Current Publications
A successful vegetable garden requires precise nutrient management to achieve maximum yields. Fertilization must provide adequate nutrients to support plant growth throughout the season. Fertilizer applications should be based on soil test recommendations and crop nutrient requirements. This fact sheet provides Utah gardeners with practical guidance and tips on soil fertilization for vegetable gardening.
Playing For The Planet: Gamified Learning And Global Health Education, Michael Dillon, Laura Bowater
Playing For The Planet: Gamified Learning And Global Health Education, Michael Dillon, Laura Bowater
Peninsula Medical School
Dr Michael J Dillon and Professor Laura Bowater emphasise the significance of gamification in global health education amidst increasingly complex challenges
The Impact Of One-To-One Peer Support On Mothers’ Personal Breastfeeding Goals And Emotional Well-Being: A Scoping Review, Khayla Timothy, Elizabeth J. O’Sullivan, Áine O’Connor
The Impact Of One-To-One Peer Support On Mothers’ Personal Breastfeeding Goals And Emotional Well-Being: A Scoping Review, Khayla Timothy, Elizabeth J. O’Sullivan, Áine O’Connor
Research Outputs: 2025-Present
Objective: To examine the impact of one-to-one peer support on mothers’ personal breastfeeding goals. Design: Scoping review guided by Arksey and O’Malley’s five-stage framework and reported in accordance with PRISMA Extension for Scoping Reviews guidelines. Qualitative data were analysed using descriptive content analysis. Quantitative data were analysed by identifying numerical trends and recurring patterns, and a concise overview of key descriptive findings was provided using frequency counts and proportions. Setting: Studies conducted across ten countries globally, identified through systematic searches of seven electronic databases and screening of reference lists. Participants: Thirty-eight studies were included: twenty quantitative, seven qualitative, six mixed …
Tree Layer Composition And Regeneration Status Of Quercus Floribunda Lindl. On Different Aspects Of Nainital Catchment In Kumaun Himalaya, Ambica Agnihotri, Ashish Tewari, Shahbaz Ali
Tree Layer Composition And Regeneration Status Of Quercus Floribunda Lindl. On Different Aspects Of Nainital Catchment In Kumaun Himalaya, Ambica Agnihotri, Ashish Tewari, Shahbaz Ali
Journal of Environmental Science and Sustainable Development
Oaks are climax-forming species found at various elevations in the Himalayas between 2100– 2700 masl. However, aspect-wise regeneration patterns of Quercus floribunda in the Nainital catchment remain poorly documented. While previous studies focused on oak forest structure, the present study provides new insight into aspect-wise variation in the regeneration stages of Q. floribunda in relation to microclimatic conditions. The present study aims to evaluate tree composition and the regeneration status of Q. floribunda forests across different slope aspects in the Nainital catchment area of the Kumaun Himalaya. Four sites representing different slope aspects were selected in the Nainital catchment. Soil …
Pneumococcal Colonization In Pediatric Patients Undergoing Hematopoietic Cell Transplantation, Liset Olarte, Jennifer E Schuster, Ibrahim Ahmed, Kristina G Hulten
Pneumococcal Colonization In Pediatric Patients Undergoing Hematopoietic Cell Transplantation, Liset Olarte, Jennifer E Schuster, Ibrahim Ahmed, Kristina G Hulten
Faculty, Staff and Students Publications
Despite the increased risk of invasive pneumococcal disease among pediatric hematopoietic cell transplant (HCT) recipients, pneumococcal colonization has not been evaluated in this population. We prospectively assessed longitudinal pneumococcal colonization in 22 pediatric HCT recipients from conditioning therapy to 100 days post-HCT. A higher likelihood of pneumococcal colonization was observed in the late post-HCT period (weeks 9-14) compared with the early post-HCT period (weeks 1-8), with odds increasing with each additional week after conditioning.IMPORTANCEThis is the first study to longitudinally evaluate pneumococcal colonization in pediatric hematopoietic cell transplant (HCT) recipients from the onset of conditioning therapy to 100 days post-HCT. …
Tau Pathology In Epilepsy: Emerging Mechanisms And Translational Opportunities, Arjune Sen, Xin You Tai, Aristea Galanopoulou, Maria Thom, Eleonora Aronica, Lucy Vivash, Martin Hardmeier, Action Amos, Stephan Rueegg, Matthias Koepp, Yaroslav Winter, Christoph Helmstaedter, Jeffrey L Noebels, Hilal A Lashuel, Terence J O'Brien
Tau Pathology In Epilepsy: Emerging Mechanisms And Translational Opportunities, Arjune Sen, Xin You Tai, Aristea Galanopoulou, Maria Thom, Eleonora Aronica, Lucy Vivash, Martin Hardmeier, Action Amos, Stephan Rueegg, Matthias Koepp, Yaroslav Winter, Christoph Helmstaedter, Jeffrey L Noebels, Hilal A Lashuel, Terence J O'Brien
Faculty, Staff and Students Publications
The onset of epilepsy in adulthood occurs most commonly after 55 years of age. Given the ageing global population, this disorder represents an increasing burden on healthcare and society. The bidirectional link between epilepsy and dementia is a focus of intense research with underlying tau pathology highlighted as a potential mechanistic link. In this review, we examine the evidence for tau-related neurodegenerative processes in epilepsy beginning with how changes in biochemical and structural properties of the tau protein can lead to abnormal phosphorylation and pathological aggregation. We consider the role of tau in seizure occurrence and cognitive difficulties in experimental …