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Articles 105721 - 105750 of 2920190
Full-Text Articles in Entire DC Network
Accountability And Efficiency: Compiled Case Studies On Economic Development, Spending, And Global Markets, Jacob W. Grimsley
Accountability And Efficiency: Compiled Case Studies On Economic Development, Spending, And Global Markets, Jacob W. Grimsley
Honors Theses
This is a compilation of cases worked throughout the course of one year. These cases were created and assigned for an accountancy course focused on research and writing. The cases focus on accounting related topics, while also pertaining to political happenings as well as general economic topics.
Case 02 was completed in collaboration with other honors students, and these students are indicated on the page preceding this case.
Cases 05 and 06 pertain to a semester-long project focused on the development of a Mississippi based business. This case was also completed with the help of other students, as indicated on …
Murray Grading Method: Impacts On Student Self-Efficacy, Stephanie E. Handford
Murray Grading Method: Impacts On Student Self-Efficacy, Stephanie E. Handford
Honors Theses
Pre-existing assessment methods in engineering lack the ability to ensure student mastery of material, simulate real world situations, and often have ambiguity in the valuation of grades. The goal of this study is to eliminate or reduce those shortcomings by evaluating the effectiveness of a modified no-partial-credit assessment method, the Murray Grading Method. Historical data alongside an introductory statics course cohort provided data for how the Murray Grading Method impacted student grades, course opinion, self-efficacy, and study methods. The Murray Grading Method demonstrated little to no changes in course grade averages while significantly improving the lowest grades, thus increasing the …
From Fraud To Future: Accountancy Case Studies On Financial Illusions, Policy Failures, And The Economic Renaissance Of Mississippi’S Broadband Initiative, Hayden Brennan Adams
From Fraud To Future: Accountancy Case Studies On Financial Illusions, Policy Failures, And The Economic Renaissance Of Mississippi’S Broadband Initiative, Hayden Brennan Adams
Honors Theses
This Honors Practicum is a compilation of case studies completed under the supervision of Dr. Victoria Dickenson across two semesters of the course Accountancy 420 — Independent Study. The first semester (Fall 2023) of case studies involved both individual and group case studies examining various geopolitical implications of contemporary accounting, as well as the surge in environmental, social, and governance (ESG) regulations affecting financial reporting. The second semester (Spring 2024) was mostly centered around a collaborative Mississippi economic development proposal project conducted by four other students and myself. In our project, we construct a business plan for a start-up broadband …
Analyzing Economic Trends: Perspectives On Economic Development And Policy Debates, Olivia Boyce
Analyzing Economic Trends: Perspectives On Economic Development And Policy Debates, Olivia Boyce
Honors Theses
This thesis is a combination of six case studies completed during the 2023-2024 academic school year. The studies were written under the direction and supervision of Dr. Victoria Dickinson during the Honors Accountancy 420 course and in accordance with the Sally McDonnell Barksdale Honors College and the Patterson School of Accountancy. Each case study explored different aspects of the accounting profession, while focusing in on analyzing economic trends. Case one discussed the unawareness of Chinese entities joining the United States stock market using a reverse merger process. This case showed the difficulties in enacting change in the U.S. government and …
Cardiovascular Disparities In Mississippi: A Sociological Study Of Heart Health Literacy Among University Students, Laney Etheridge
Cardiovascular Disparities In Mississippi: A Sociological Study Of Heart Health Literacy Among University Students, Laney Etheridge
Honors Theses
Mississippi ranks among the worst states in the United States for cardiovascular health, with high rates of heart disease, obesity, and hypertension. This thesis examines how race and gender influence heart health literacy and behavioral practices among University of Mississippi students. Utilizing a mixed-methods approach, this study combines quantitative survey data from a stratified random sample of 1,000 students with qualitative interviews from a public health professional specializing in cardiovascular health and a student heavily involved with on-campus heart health programs. The findings suggest that disparities in heart health literacy both align and differ with broader social stratification patterns observed …
Effects Of Acute Exercise On Cognition: Consideration Of Potential Moderators, Mary G. Jackson, Lucy Wilson, Mara Liston, Elizabeth Gaines, Mckenzie Cotten, Reese Carwile
Effects Of Acute Exercise On Cognition: Consideration Of Potential Moderators, Mary G. Jackson, Lucy Wilson, Mara Liston, Elizabeth Gaines, Mckenzie Cotten, Reese Carwile
Honors Theses
The present thesis aims to determine the effects, if any, of six potential moderators on the effects of acute moderate-intensity exercise on cognitive functioning. The modes of exercise undertaken by the participants included treadmill (Experiment 1) and stationary bike (Experiment 2) exercise. Participants in each experiment either exercised or rested for twenty minutes and then participated in either a memory recall task or cognitive functioning (“Stroop”) task. The bouts of either exercise or rest on the stationary bike were followed by a rest period during which the participant would be exposed to either standard air oxygen levels (normoxia) or hypoxic …
Extracting Renewables: A Capabilities Approach To A Just Transition Crisis, Mateos Lozano
Extracting Renewables: A Capabilities Approach To A Just Transition Crisis, Mateos Lozano
Honors Theses
Extraction of cobalt and lithium is often regarded as necessary to facilitate a successful transition to renewable energy so that global warming can be limited to 2°C. At the same time, many current cobalt and lithium extraction practices contribute to environmental destruction, expose workers to toxic contaminants, and sometimes involve child labor. This thesis argues that cobalt and lithium extraction, if permissible, must be conducted in a manner compatible with the normative obligations of justice and fairness. I first explain notable differences between prominent types of cobalt and lithium extraction and note how each impacts people and the environment. Then, …
Overlooked: The Nuanced Struggles Of Autistic Women, Autumn L. Payne
Overlooked: The Nuanced Struggles Of Autistic Women, Autumn L. Payne
Honors Theses
Overlooked is a documentary short film that seeks to shine a light on the nuanced struggles of autistic women in a neurotypical world. This short documentary consists of three interviews with autistic women from different backgrounds. Each diagnosed during a different stage of life, they reflect on their journeys to receiving an Autism Spectrum Disorder (ASD) diagnosis and its impact on their lives. These conversations reveal an overwhelming lack of resources for autistic people, especially for women, people of color, and members of the LGBTQIA+ community. With the diagnosis criteria for ASD being historically based on white males, women and …
An Articulation And Defense Of American Nationality, Clara E. White
An Articulation And Defense Of American Nationality, Clara E. White
Honors Theses
This thesis seeks to first provide an articulation of American nationality based on the five components outlined in David Miller’s book On Nationality. These components are Geographical Connection, Constitutive Belief, Public Culture, Active Identity, and Historical Continuity. In the case of American national identity, these components are satisfied by the founding documents meant to govern the United States as well as the sum of how citizens have interacted with these texts throughout history. Secondly, this thesis composes a defense from two widely known theories of political thought that I believe violate the articulated American nationality. These views are labeled as …
Asymmetric Recovery: Understanding The Differences In Commercial And Residential Recovery Patterns Following The 2008 Financial Crisis, Avery J. Flynn
Asymmetric Recovery: Understanding The Differences In Commercial And Residential Recovery Patterns Following The 2008 Financial Crisis, Avery J. Flynn
Honors Theses
The 2008 financial crisis revealed differences in economic recovery patterns between businesses and households. This study analyzes the asymmetry in loan delinquency rates between commercial and residential sectors, with data showing commercial rates peaked at 8.51% in 2010 while residential rates reached 10.88%, followed by significantly different recovery trajectories.
The research investigates how differing legal protections created varying incentives to cut costs. Through analyzing Federal Reserve data, Census Bureau surveys, and expenditure records, this study found the commercial sector recovered 64% within three years of its peak, compared to only 17% for the residential sector.
During the recession, businesses reduced …
Academic Burnout In Human Anatomy & Physiology I Students, Shivani Shukla
Academic Burnout In Human Anatomy & Physiology I Students, Shivani Shukla
Honors Theses
Human Anatomy and Physiology I is the study of the function and structure of the human body. It is a challenging class that many students have to take for their undergraduate degree. Due to the vast information that is given in this complex class, students can struggle with understanding the material and knowing how to study thus leading to burnout in the course. Understanding why students undergo burnout in their courses could uncover ways that professors and institutions could help the students to prevent burnout. The goal of this study was to determine the level of burnout in Human Anatomy …
An Adaptation Of Nonlinear Aerodynamic Models For Non-Traditional Control Effectors, Christian R. Bolander, Douglas F. Hunsaker
An Adaptation Of Nonlinear Aerodynamic Models For Non-Traditional Control Effectors, Christian R. Bolander, Douglas F. Hunsaker
Engineering Education Faculty Publications
This paper presents the development of a novel aerodynamic model tailored for the Bio-Inspired Rotating Empennage (BIRE), a non-traditional fixed-wing aircraft empennage inspired by avian flight. The BIRE replaces the conventional vertical stabilizer with an extra degree of freedom for the horizontal stabilizer, which is allowed to rotate about the body-fixed x axis. This empennage is similar to the tail of a bird, and allows control of both longitudinal and lateral moments. However, such a design introduces complex nonlinear longitudinal and lateral aerodynamic interactions, not typically accounted for in most fixed-wing aircraft aerodynamic models below stall. This work presents a …
American Football Internal Helmet Padding Material And Design Testing, Spencer J. Pigman
American Football Internal Helmet Padding Material And Design Testing, Spencer J. Pigman
Honors Thesis
Football helmets have evolved significantly to improve player safety and reduce the risk of concussions and traumatic brain injuries. Early leather designs offered minimal protection, while modern helmets use advanced materials to absorb and distribute impact forces more effectively. To support ongoing helmet safety research, a custom 3D-printed headform modeled from a human scan was equipped with a WitMotion BWT901BLECL5.0 accelerometer and used in controlled drop tests. The study evaluated various internal padding materials including spray foam, two sizes of bubble wrap, Oobleck, scrub sponges, KTOESHEO foam, Hijelyn air pillows, and the standard padding from a Riddell Victor youth helmet. …
Revenue Cycle Management: Audit Of A Primary Care Clinic, Strategy, & Future Improvements, Izaak Colgrove
Revenue Cycle Management: Audit Of A Primary Care Clinic, Strategy, & Future Improvements, Izaak Colgrove
Capstone: Master of Health Administration
Healthcare practices that offer primary care, an essential service, are dependent upon financial liquidity for survival. This project evaluated the financial wellbeing of a local primary care clinic through the process of revenue cycle evaluation. The clinic has transitioned from the startup phase into a period of growth and as the clinic scales up, it faces new challenges related to revenue cycle management (RCM) and overall operational efficiency.
For any practice, the process of evaluating the revenue cycle, formally known as Revenue Cycle Management (RCM), is critical to help ensure financial stability. Central to managing the revenue cycle is the …
Multi-Parametric Quantitative Evaluation Of Murine Cervical Remodeling During Pregnancy And Postpartum, Yan Yan, Jose Galaz, Joshua Marvald, Tanzy Love, Steven Yellon, Nardhy Gomez-Lopez, Mohammad Mehrmohammadi
Multi-Parametric Quantitative Evaluation Of Murine Cervical Remodeling During Pregnancy And Postpartum, Yan Yan, Jose Galaz, Joshua Marvald, Tanzy Love, Steven Yellon, Nardhy Gomez-Lopez, Mohammad Mehrmohammadi
2020-Current year OA Pubs
Cervical remodeling during pregnancy is a critical process that, if untimely, can lead to complications such as preterm birth (PTB). This study introduces a novel multi-parametric approach combining non-invasive imaging modalities to quantify cervical tissue changes during pregnancy and postpartum in a murine model. By integrating ultrasound-based measurements of cervical length, photoacoustic imaging of the collagen-to-water ratio, and elastography for tissue elasticity alongside histological assessments, this method provides a comprehensive evaluation of cervical remodeling. The findings reveal that combining these parameters significantly improves the accuracy of gestational age prediction compared to individual measurements, with a tri-parametric model achieving 85.3% prediction …
Outcomes Of 1,021 Consecutive Cases Utilizing A Triple Tapered Collared Stem And Automated Broaching System, Ravi R Agrawal, Maria T Schwabe, Helena F Barber, Ethan Blum, Joseph T Gibian, Ryan M Nunley, Ilya Bendich
Outcomes Of 1,021 Consecutive Cases Utilizing A Triple Tapered Collared Stem And Automated Broaching System, Ravi R Agrawal, Maria T Schwabe, Helena F Barber, Ethan Blum, Joseph T Gibian, Ryan M Nunley, Ilya Bendich
2020-Current year OA Pubs
No abstract provided.
Letter To The Editor On “Timing Of Puberty Suppression In Transgender Adolescents And Sexual Functioning After Vaginoplasty (Van Der Meulen Et Al., 2024)”, Alison Clayton, Jilles Smids, Kathleen Mcdeavitt
Letter To The Editor On “Timing Of Puberty Suppression In Transgender Adolescents And Sexual Functioning After Vaginoplasty (Van Der Meulen Et Al., 2024)”, Alison Clayton, Jilles Smids, Kathleen Mcdeavitt
Faculty, Staff and Students Publications
No abstract provided.
Direct Computations Of Spatially Resolved Viscoelastic Moduli Of Biomolecular Condensates, Liwen Gu
Direct Computations Of Spatially Resolved Viscoelastic Moduli Of Biomolecular Condensates, Liwen Gu
McKelvey School of Engineering Graduate Student Theses & Dissertations
Biomolecular condensates are viscoelastic materials formed by liquid-liquid phase separations (LLPS) of biopolymers. In this study, we develop a modified graph Laplacian-based collective model to characterize viscoelastic heterogeneity within condensates based on results of lattice-based Metropolis Monte Carlo (MMC) simulations. By integrating random graph models and simulations of A1-LCD, a type of intrinsically disordered protein, we examine how network topology influences storage modulus, loss modulus, crossover frequency, and relaxation time spectra. Our results reveal a strong correlation between topological features and mechanical response, with the condensate interior exhibiting higher stiffness and faster relaxation than the interface. The relaxation spectra provide …
Pulse Pressure, White Matter Hyperintensities, Andcognition: Mediating Effects Across The Adult Lifespan, Jade Hannan, Sarah Newman-Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman-Norlund, Chris Rorden, Julius Fridriksson, Leonardo Bon, Nicholas Riccardi
Pulse Pressure, White Matter Hyperintensities, Andcognition: Mediating Effects Across The Adult Lifespan, Jade Hannan, Sarah Newman-Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman-Norlund, Chris Rorden, Julius Fridriksson, Leonardo Bon, Nicholas Riccardi
Faculty Publications
Objectives: To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition.
Methods: Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment scores for231 stroke- and dementia-free adults were retrospectively obtained from the Aging Brain Cohort study. Total WMH load was determined from T2-FLAIR magnetic resonance scans using the TrUE-Net deep learning tool for white matter segmentation. In separate models, we used mediation analysis to assess whether pulse pressure or MAP mediates the relationship between age and total …
Pulse Pressure, White Matter Hyperintensities, And Cognition: Mediating Effects Across The Adult Lifespan, Jade Hannan, Sarah Newman-Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman-Norlund, Chris Rorden, Julius Fridriksson Ph.D., Leonardo Bonilha
Pulse Pressure, White Matter Hyperintensities, And Cognition: Mediating Effects Across The Adult Lifespan, Jade Hannan, Sarah Newman-Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman-Norlund, Chris Rorden, Julius Fridriksson Ph.D., Leonardo Bonilha
Faculty Publications
Objectives: To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition.
Methods: Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment scores for231 stroke- and dementia-free adults were retrospectively obtained from the Aging Brain Cohort study. Total WMH load was determined from T2-FLAIR magnetic resonance scans using the TrUE-Net deep learning tool for white matter segmentation. In separate models, we used mediation analysis to assess whether pulse pressure or MAP mediates the relationship between age and total …
Allogeneic Chimeric Antigen Receptor T-Cell Products Cemacabtagene Ansegedleucel/Allo-501 In Relapsed/Refractory Large B-Cell Lymphoma: Phase I Experience From The Alpha2/Alpha Clinical Studies, Frederick L Locke, Javier L Munoz, Michael T Tees, Lazaros J Lekakis, Sven De Vos, Rajneesh Nath, Don A Stevens, Shahbaz A Malik, Geoffrey P Shouse, Mehdi Hamadani, Olalekan O Oluwole, Miguel-Angel Perales, David B Miklos, Paul W Fisher, Amy Feng, Lynn Navale, John B Le Gall, Sattva S Neelapu
Allogeneic Chimeric Antigen Receptor T-Cell Products Cemacabtagene Ansegedleucel/Allo-501 In Relapsed/Refractory Large B-Cell Lymphoma: Phase I Experience From The Alpha2/Alpha Clinical Studies, Frederick L Locke, Javier L Munoz, Michael T Tees, Lazaros J Lekakis, Sven De Vos, Rajneesh Nath, Don A Stevens, Shahbaz A Malik, Geoffrey P Shouse, Mehdi Hamadani, Olalekan O Oluwole, Miguel-Angel Perales, David B Miklos, Paul W Fisher, Amy Feng, Lynn Navale, John B Le Gall, Sattva S Neelapu
Faculty, Staff and Student Publications
Purpose: Off-the-shelf, allogeneic CD19 chimeric antigen receptor (CAR) T-cell products may improve access to treatment versus autologous ones. We report the phase I experience of the allogeneic CD19 CAR T-cell product cemacabtagene ansegedleucel (cema-cel) and its predecessor, ALLO-501, in CD19 CAR T-naïve patients with relapsed/refractory large B-cell lymphoma (R/R LBCL).
Methods: In the ALPHA2/ALPHA studies, the safety and efficacy of allogeneic CD19 CAR T cells were evaluated in CD19 CAR T treatment-naïve patients with R/R LBCL. Patients received healthy donor-derived, human leukocyte antigen-unmatched cema-cel/ALLO-501 following a 3-day lymphodepletion regimen of fludarabine (30 mg/m2 once daily), cyclophosphamide (300 or 500 mg/m2 …
El Podcast Como Herramienta Pedagógica Entre Docentes Del Nivel Superior En Una Escuela Privada Del Este De Puerto Rico, Lorell Marie Varela Morales
El Podcast Como Herramienta Pedagógica Entre Docentes Del Nivel Superior En Una Escuela Privada Del Este De Puerto Rico, Lorell Marie Varela Morales
Theses and Dissertations
El objeto del estudio se centró en comprender la disposición de los docentes de nivel
superior hacia el uso de podcasts como recurso pedagógico en una escuela del este de Puerto Rico. Este análisis abordó las percepciones, actitudes y factores que influyen en la
aceptación de esta innovadora herramienta educativa. Se identificaron los beneficios
percibidos de los podcasts como herramienta pedagógica, así como los desafíos y
preocupaciones asociados con su integración en el proceso de enseñanza-aprendizaje.
Los modelos teóricos que sustentan este estudio se basaron en la revisión de especialistas
en innovación y aceptación tecnológica por parte de los docentes …
Advancing Dermatologic Equity For Individuals With Autism Through Awareness And Structural Reform, Radhika Misra, Renee Chang, Olumayowa T. Adebiyi, Maria Orbe, Donna Pham, Kaitlyn Miner, Kelly M. Frasier
Advancing Dermatologic Equity For Individuals With Autism Through Awareness And Structural Reform, Radhika Misra, Renee Chang, Olumayowa T. Adebiyi, Maria Orbe, Donna Pham, Kaitlyn Miner, Kelly M. Frasier
Student Publications
Autism spectrum disorder (ASD), a neurodevelopmental condition affecting communication, social interaction, and sensory processing, has seen a marked increase in prevalence over the past two decades. Dermatologists are increasingly encountering patients with ASD, many of whom face compounded challenges due to mobility issues, such as reliance on wheelchairs, as well as sensory hypersensitivities and communication barriers. Despite the growing demand for specialized care, advocacy for accessible dermatologic health for individuals with ASD remains insufficient. This literature review highlights the challenges faced by this population, including higher susceptibility to certain dermatologic conditions and the significant barriers to effective clinical evaluation and …
2025 Spring Commencement, Harding University
2025 Spring Commencement, Harding University
Commencement Programs
Program for the Harding University Commencement on May 10.
Commencement Speakers:
9a.m.: Dr. Lisa Ritchie
noon: David Johnson
3p.m.: Mark Sweesy
Relationship Between Maternal Plasma Retinol And Provitamin A Carotenoids With Fetal And Infant Kidney Development, Anum Akbar
Theses & Dissertations
Vitamin A plays a critical role in fetal organ development. Studies suggest that maternal vitamin A deficiency affects fetal nephron numbers, potentially leading to smaller kidney sizes and an increased risk of chronic kidney disease later in life. However, human studies exploring maternal vitamin A's impact on fetal kidney development lack longitudinal data and within-cohort comparisons. Furthermore, the influence of provitamin A carotenoids (α-carotene, β-carotene, β-cryptoxanthin) on kidney size remains unexplored. This dissertation addresses these gaps by analyzing relationships between maternal and cord plasma retinol and provitamin A carotenoid concentrations with fetal and infant kidney sizes. Our prospective cohort …
Coxiella Burnetii Manipulation Of Membrane Contact Sites In The Intracellular Niche, Margaret F. Sladek
Coxiella Burnetii Manipulation Of Membrane Contact Sites In The Intracellular Niche, Margaret F. Sladek
Theses & Dissertations
Coxiella burnetii is a highly infectious and environmentally persistent bacterium that causes the disease Q Fever. Its intracellular home, the Coxiella-Containing Vacuole (CVV), is formed from fusion of host-derived vesicles and is rich in sterols - yet cholesterol accumulation in the CCV is bacteriolytic. Our lab’s goal is to understand how Coxiella manages intracellular cholesterol levels and survives within the host. One way Coxiella may modulate CCV cholesterol is through membrane contact sites (MCS), areas where molecular complexes bridge two organelles and exchange lipids. This thesis explores how Coxiella uses both a mammalian lipid transfer protein and bacterially-encoded effector …
Identification And Preclinical Assessment Of Novel Therapeutic Modalities In Environmental Exposure-Induced Lung Disease, Aaron D. Schwab
Identification And Preclinical Assessment Of Novel Therapeutic Modalities In Environmental Exposure-Induced Lung Disease, Aaron D. Schwab
Theses & Dissertations
Environmental lung diseases are preventable respiratory conditions either caused or made worse by inhaled environmental exposures. Contemporarily, environmental lung diseases are most associated with workplace exposures given specific occupational processes aerosolize inflammatory agents that can be inhaled at high concentrations. Although a considerable amount is known regarding immunoglobulin (Ig)E-mediated responses to environmental exposures, little is known about non-IgE mediated respiratory conditions resulting from lipopolysaccharide (LPS)-enriched organic dust exposure(s). Chronic respiratory diseases such as asthma, hypersensitivity pneumonitis, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis have all been identified as environmental lung diseases caused or exacerbated by such environmental dusts. Therapeutic …
Schistosoma Haematobium Infection In Ethiopian Children: Evaluating Praziquantel Efficacy, Nutritional Effects, And Diagnosis Using Flukecatcher, Louis Fok
Theses & Dissertations
Urogenital schistosomiasis continues to impact the wellbeing of hundreds of millions of people worldwide and remains a significant public health challenge across Ethiopia. Despite existing knowledge on the disease, there remain significant unanswered questions with regard to its treatment and diagnosis. This dissertation evaluated the efficacy of praziquantel at treating urogenital schistosomiasis, improving nutritional parameters among children and the performance of FlukeCatcher at detecting and determining the intensity of infection. In effecting this, a total of 977 children aged 5 through 15 from the Afar and Gambella regions of Ethiopia were screened for S. haematobium infection using urine filtration microscopy …
Evaluation Of The Usage And Effectiveness Of The Gross Anatomy Osteology E-Learning Module, Conor Young
Evaluation Of The Usage And Effectiveness Of The Gross Anatomy Osteology E-Learning Module, Conor Young
Theses & Dissertations
Supplementary online learning modalities have reached near ubiquity in graduate health sciences education, yet evidence about their effectiveness remains mixed. The Department of Genetics, Cell Biology, and Anatomy at UNMC recently introduced their own bespoke electronic study platform called the Osteology e-Learning Module to aid gross anatomy students in the study of osteology. To assess its effectiveness, osteology and whole gross lab practical exam scores were compared in four different content units across three school year cohorts of graduate students in the same gross anatomy class. A survey was also distributed to one cohort to capture subjective information about the …
Neurodegenerative Disease Mechanisms: Mitochondrial Impairment, Tau Aggregation, And Neuroinflammation As Central Drivers Of Disease Progression, Luis D. Estrella
Neurodegenerative Disease Mechanisms: Mitochondrial Impairment, Tau Aggregation, And Neuroinflammation As Central Drivers Of Disease Progression, Luis D. Estrella
Theses & Dissertations
The study of the intricate molecular mechanisms behind the pathology of neurodegenerative diseases has become a primary research area in the past decades. The major branches of these studies involve both disease progression and disease pathogenesis, in which neuroscientists have studied, and continue to study, the role that mitochondrial dysfunction, aberrant protein aggregation (like Tau), and immune cell reactions have on these. However, more recent studies have shined light to the fact that these three pathological features are not independent from one another and that their synchronous contributions may be the ultimate driver of neurodegeneration. This dissertation encompasses four different …