Digital Commons Network^™

Dean James Nelson Frierson Files - 1920-1946 Guide, James Nelson Frierson

Frierson, James Nelson (1920-1946)

No abstract provided.

Cyclohexylamine, The Principal Metabolite Of Cyclamate, Contracts The Epididymal Vas Deferens Of Rats By Affecting Endogenous Catecholamine Release Via Postsynaptic Α1aand Presynaptic Α2-Adrenoceptors In A Calcium-Dependent Manner, Yuh-Fung Chen, Yu-Wen Wang, Huei-Yann Tsai

BioMedicine

Background: Cyclohexylamine (CHA) is a principal metabolite of cyclamate, which was once one of the most prominently consumed non-sugar sweeteners. Earlier studies suggested that long-term use of cyclamate might be carcinogenic and genotoxic; however, no consistent evidence supports an association between cyclamate and cancer risk. However, this issue remains interesting. Cyclamate can be metabolized to CHA by the intestinal bacteria in humans and some animals. Previous reports indicated CHA could induce atrophy of rat testes and affect rat fertility, as well as contract rat vas deferens. However, the contractile mechanisms of CHA on rat vas deferens remains poorly understood. This …

The Protective Role Of Astaxanthin Against Oxidative Stress And Inflammation In Peritoneal Dialysis Rats, Ratih Tri Kusuma Dewi, Bambang Purwanto, Brian Wasita, Vitri Widyaningsih

BioMedicine

Background: Prolonged exposure of peritoneal membrane to dialysate solution is known to cause fibrosis mediated by imbalanced inflammatory response and oxidative stress. In this context, proinflammatory cytokines including TGF-β and IL-1β, along with oxidative stress markers namely SOD and MDA, present in circulation, could serve as indicators of fibrosis. This phenomenon has the potential to interfere with the optimization of Chronic Kidney Disease (CKD) treatment. Other oral antioxidant supplements have been widely studied to prevent peritoneal damage, but investigations regarding Astaxanthin (AST) effect on fibrosis marked with proinflammatory cytokine are still limited.

Aims: This study aimed to investigate the protective …

Bridging The Divide: Gaps In Mental Health Resources For K-12 Students In Nevada, Nicole Diaz Del Valle

Student Research

Since 2014, Nevada has consistently ranked among the bottom five states, if not last, in the nation for youth mental health, with more than 34,000 youth reporting experiencing thoughts of suicide in 2025 (U.S. Department of Health and Human Services, 2023). The state’s student-to-counselor ratio stands at 456 to 1, nearly double the recommended 250 to 1 (American School Counselor Association, 2024). In Southern Nevada, these challenges are compounded with persistent provider shortages, chronic underfunding, and a fragmented system of care. This policy brief focuses on the barriers preventing students from receiving timely, effective mental health support in school settings …

No. 41: Crisis, Pandemic Precarity And Food Insecurity Among Migrant Households During The Covid-19 Pandemic In Quito, Ecuador, Mercedes Eguiguren, Taymi Milán, Cheryl Martens

Migration and Food Security (MiFOOD) Network

This study examines the food insecurity experiences of Venezuelan migrants in Quito, Ecuador, within the broader context of the Venezuelan crisis, regional migration responses, and the structural precarity migrants face. Moving beyond the dominant “migration crisis” narrative, this paper adopts a crisis-living framework to analyze how protracted instability and pandemic precarity shape migrants’ experiences. Based on a 2023 survey of migrants and refugees who lived in Quito throughout the COVID-19 pandemic, the findings reveal that food insecurity is a persistent challenge, disproportionately affecting female-led and extended households. Key factors influencing food insecurity include job instability and deteriorating employment conditions, limited …

Plm-Dbps: Enhancing Plant Dna-Binding Protein Prediction By Integrating Sequence-Based And Structure-Aware Protein Language Models, Suresh Pokharel, Kepha Barasa, Pawel Pratyush, Dukka B. Kc

Michigan Tech Publications

DNA-binding proteins (DBPs) play a crucial role in gene regulation, development, and environmental responses across plants, animals, and microorganisms. Existing DBP prediction methods are largely limited to sequence information, whether through handcrafted features or sequence-based protein language models (PLMs), overlooking structural cues critical to protein function. In addition, most existing tools are trained for general DBP predictions, which are often not accurate for plant-specific DBPs due to the unique structural and functional properties of plant proteins. Our work introduces PLM-DBPs, a deep learning framework that integrates both sequence-based and structure-aware representations to enhance DBP prediction in plants. We evaluated several …

Associations Between Breastfeeding Duration And Weight Status Transitions In Early Childhood, Hyojun Park, Eric N. Reither

Sociology and Anthropology Faculty Publications

Empirical evidence with respect to the protective effect of breastfeeding on childhood obesity remains inconclusive, and studies on sex-specific associations are sparse. We investigated whether (H1) longer breastfeeding duration reduces the risk of entry into elevated body mass (EBM); and (H2) longer breastfeeding duration increases the likelihood of exit from EBM. Using the Early Childhood Longitudinal Study, Birth Cohort (ECLS-B), our sample comprised 10,550 mother-child pairs after excluding 100 non-biological pairs. The ECLS-B assessed children from 9 months of age through kindergarten, spanning infancy through 7 years of age. We used two transitions in weight status (i.e., entry to EBM …

Lost In Transition: An Examination Of The Burden Of Choice In Samuel Beckett's Dramatic Works, Sam Parrish

English Theses

Samuel Beckett's plays, Waiting for Godot and Endgame, provide ample room for applying existential and speech act theories to examine the goals of the characters. In analyzing the exchanges between these characters, the audience becomes aware of the phenomenon of miscommunication and how it alienates the characters. This thesis furthers the discussion of Beckett's intentions regarding the human experience as embodied on stage by examining the text of the plays, rather than any specific performances. Specifically, I develop a framework that identifies a main character within each of the plays discussed, and how the interactions between that main character and …

Introduction

The Journal of Contemporary Legal Issues

In November 2023, the Institute for Law and Philosophy at the University of San Diego School of Law convened a Symposium on Andrew Koppelman’s recent book, published in 2022, Burning Down the House: How Libertarian Philosophy Was Corrupted by Delusion and Greed. The argument of Andy Koppelman’s book is that whereas modern American libertarianism began admirably with Friedrich Hayek’s corrective to the Depression-era vogue for central economic planning, libertarianism has since devolved into a toxic blend of anarchism, greed, disdain for the weak, and rationalization for environmental catastrophe.

The papers from the Symposium are published in this issue of …

Will The Real F.A. Hayek Please Stand Up!, Eric Mack

The Journal of Contemporary Legal Issues

In this essay, I will argue that neither of these two presentations of Hayek represent the real Hayek. In Part II of this essay, I criticize Koppelman’s contention that there is little distance, if any, between Hayek’s stance on distributive justice and Rawls’s difference principle. In Part III of this essay, I dispute Koppelman’s claim that Hayek is quite receptive to the development and expansion of the regulatory-administrative state. Each of these stances is rejected by Hayek for the same sorts of reasons that stand behind his rejection of central economic planning. Hayek’s critique of central economic planning, his rejection …

We Didn’T Start The Fire: For And Against Koppelman On The Corruption Of Libertarianism, Roderick T. Long

The Journal of Contemporary Legal Issues

At the philosophic core of libertarianism is a set of market-oriented commitments that are entirely compatible with, and indeed congenial to, traditional leftist concerns with the well-being of the disadvantaged in society. But over the past several decades, the libertarian movement has fallen increasingly under the spell of toxic, callous, right-wing versions of libertarianism that scorn empathy while championing the cause of the economic winners in society at the expense of those who lose out.

That’s one way of stating the central thesis of Andrew Koppelman’s book Burning Down the House. And that thesis, so stated, is one I …

Freedom From Libertarianism, Joseph Fishkin

The Journal of Contemporary Legal Issues

Andrew Koppelman’s new book Burning Down the House is a guide to some of the late stages of the libertarian collapse. It’s a book whose many virtues include its clear and simple prose style. As a result of that style, and its generally straightforward exposition, I think this book will be of real use to many people, perhaps especially to free-thinking former libertarians who are engaged in a project of self-deprogramming. The book makes a nice holiday gift to the former libertarian or wavering libertarian in your life who would like to learn more about the arc of how it …

Notes From A Serf, Rachel Lu

The Journal of Contemporary Legal Issues

F. A. Hayek would have hated Obamacare. This must be distinctly understood, or nothing wonderful can come of the argument I am going to relate.

Fusionism, Not Libertarianism, Burned Down The House, Kevin Vallier

The Journal of Contemporary Legal Issues

In Burning Down the House, Andrew Koppelman has two goals: one philosophical and one sociological. The philosophical goal is to separate the wheat from the chaff in libertarian thought. Koppelman embraces the merits of F. A. Hayek’s arguments for markets. But he stridently rejects the radical libertarianism of Murray Rothbard, Robert Nozick, and Ayn Rand. The radicals are out, and the moderates are in. Hayek must increase, and Rothbard must decrease.

The sociological thesis is that radical libertarian ideology significantly influences the modern GOP and American conservatism. Koppelman sees the pathologies of the contemporary right as drawing from the …

Burning Questions: A Response To Fishkin, Long, Lu, Mack, And Vallier, Andrew Koppelman

The Journal of Contemporary Legal Issues

I’m indebted to Larry Alexander and Steve Smith for organizing this conference, and to Joseph Fishkin, Roderick Long, Rachel Lu, Eric Mack, and Kevin Vallier for their thoughtful responses to my book, Burning Down the House: How Libertarian Philosophy Was Corrupted by Delusion and Greed. When San Diego organized this conference, I gave them the names of the people whom I was most eager to engage with, scholars I admire despite some deep disagreements. They have forced me to sharpen my own views. I am very lucky.

Hermeneutic Theory And The Priority Of Constitutional Meaning, Tyler S. Moore

The Journal of Contemporary Legal Issues

Can the understanding of a law be separated from its application? Despite the increasing convergence between schools of constitutional interpretation in the United States, this question remains central. One the one side are so-called “new originalists” for whom the distinction between understanding and application (or “interpretation” and “construction” as they call it) is necessary to separate a more objective step in the interpretive process from a more subjective one. On the other are “living constitutionalists,” many of whom suggest that defining a neat boundary between these two stages is impossible. When judges decide cases, they do not (and perhaps cannot) …

The Fundamental Right To Polygynous Marriage, Ronald C. Den Otter

The Journal of Contemporary Legal Issues

This Article is about why the argument in favor of a constitutional right to polygynous marriage, predicated on the importance of personal autonomy, is considerably stronger than the sex equality arguments against it. For the most part, legal scholars have arrived late on the scene, not treating the topic with the kind of care that it deserves. Instead of relying upon equal protection analysis, I shall engage in a fundamental rights critique of opposition to polygynous marriage. In doing so, I will discuss two considerations that remain central to such analysis: the value of autonomy (understood as personal choice in …

What Is The Automotive Recycling Industry And Its Prospective Future?, Andres M. Rabago

Sustainable Supply Chain Management

An explanation of the current automotive recycling industry. Looking in depth at aspects such as its sustainability and key businesses involved in the industry and the roles they play in it.

Decompression With Intradural Dissection For The Chiari Malformation Type I: Toward Eliminating Wound Complications, Anna Lin, Lindsey Asti, Marissa Carroll, Jeffrey Campbell, Jospeh Piatt

Department of Neuroscience Faculty Papers

BACKGROUND: There is continuing conversation about surgical technique in the management of the Chiari malformation. Popular options include osseous decompression alone, decompression with dural splitting, and decompression with intradural dissection (DID) and duraplasty. Wound complications after intradural dissection are a persistent problem. The current study of an institutional series examines wound complication rates after intradural dissection without dural closure.

METHODS: A retrospective single-institution chart review was performed for patients < 21 years with Chari malformation type I who underwent DID without dural closure and had at least 6 months of follow-up. Bone removal corresponded to the area of attachment of the rectus capitis posterior minor muscles together with laminectomy of the atlas. The trapezius and semispinalis capitis muscles were retracted but were not separated from the occiput.

RESULTS: A total of 76 patients were treated from May 2010 through May 2024. Thirty-eight (50.0%) patients had syringomyelia. The median age at surgery was 9 years (interquartile range [IQR] 4-13), …

Near-Earth Object (Neo) Surveyor Introduction “Neos”, Brent Carlsen

Space Dynamics Laboratory Publications

NEOS

- Near-Earth Object Surveyor (NEOS)

- Its Mission

- Its Importance

- How it’s built

- What you will see today

• Where piece parts were made
• Where it will be assembled
• Where it will be tested

Jennifer Oldham V. Penn State University

2025 Decisions

USDC for the Middle District of Pennsylvania

James Biear V. Attorney General United States Of America

2025 Decisions

USDC for the Middle District of Pennsylvania

A Quantitative And Qualitative Analysis Of The Workplace Challenges Experienced By Women, Ahmed Mohammed Almousa

Dissertations and Theses

This dissertation explores the persistent workplace challenges experienced by women through three interrelated studies using both quantitative and qualitative methods. Despite decades of progress, women continue to face structural barriers, sexual harassment, gender discrimination, and emotional labor demands that shape their professional experiences.

The first study analyzes GSS data to examine the impact of the #MeToo movement on self-reports of sexual harassment and gender discrimination. Results show an increase in reporting sexual harassment among White men and Women of color. With respect to men of color and white women, the results were not significant or did not show an increase. …

Benchmarking Machine Learning Models In Lesion-Symptom Mapping For Predicting Language Outcomes In Stroke Survivors, Deepa Tilwani, Christian O'Reilly, Nicholas Riccardi, Valerie L. Shalin, Dirk B. Den Ouden, Julius Fridriksson, Svetlana V. Shinkareva, Amit P. Sheth, Rutvik H. Desai

Communication Sciences and Disorders Faculty Articles and Research

Several decades of research have investigated the neural connections between stroke-induced brain damage and language difficulties. Typically, lesion-symptom mapping (LSM) studies that address this connection have relied on mass univariate statistics, which do not account for multidimensional relationships between variables. Machine learning (ML) techniques, which can capture these intricate connections, offer a promising complement to LSM methods. To test this promise, we benchmarked ML models on structural and functional MRI to predict aphasia severity (N = 238) and naming impairment (N = 191) for a cohort of chronic-stage stroke survivors. We used nested cross-validation to examine performance along …

Long-Term Neurocognitive And Behavioral Outcomes In Survivors Of Pediatric Brain Tumors: A Systematic Review, Tirath Patel, Pulkit Johar, Vaishnavi Kanisetti, Megan Szobody, Tori Sayers, Sriya Gullapalli, Murali Yallapu, Mushfiq Hassan Shaikh, Nikhilesh Anand, Kelsey Baker, Bharathi Gadad

School of Medicine Publications

Background: Brain tumors are among the most common neoplasms in children. These patients suffer from neurocognitive impairment, treatment-related side effects, and experience a subpar quality of life (QoL), affecting academic endeavors, social interaction, and mental wellbeing.

Methods: This review investigated different long-term neurocognitive and behavioral outcomes in pediatric brain tumor survivors and evaluated various effective treatment methods. We identified 75 relevant articles published between 2019 and 2024 using PubMed, PMC, Embase, and Google Scholar databases. Duplicates were removed, and 14 studies were finally selected following the PRISMA guidelines. Initial observations noted significant variations in the study methodologies and inclusion criteria. …

Development Of An Age-Appropriate Household Dysfunction Measure And Its Concurrent Validity With Multiple Outcomes Among Middle School Adolescents In Southeast Texas, Sumaita Choudhury, Timothy J Walker, Emily T Hébert, Christine M Markham, Ross Shegog, Robert C Addy, Melissa F Peskin

Faculty, Staff and Student Publications

Existing adverse childhood experience (ACE) measures include a limited number of household dysfunction (HD) items and the use of adult-oriented language that is not always appropriate for middle schoolers. We developed an age-appropriate 10-item HD measure informed by previously validated ACE measures and tested its concurrent validity with dating violence (DV) perpetration, lifetime substance use, and mental health outcomes among middle schoolers in Southeast Texas. This cross-sectional study used the baseline data from a DV prevention intervention program for sixth graders (N = 126), Me & You Tech. Baseline data were collected from March 2023 to April 2023. To …

Cotton/Soybean Insect Newsletter, May 29, 2025, Jeremy K. Greene

Clemson University Cotton/Soybean Insect Newsletter

No abstract provided.

Cotton/Soybean Insect Newsletter, May 29, 2025, Jeremy K. Greene

Clemson University Cotton/Soybean Insect Newsletter

No abstract provided.

Implementation Outcomes And Associated Constructs From The Consolidated Framework For Implementation Research Among Churches Trained Online To Implement Faith, Activity, And Nutrition In A National Implementation Study, Sara Wilcox Phd, Ruth P. Saunders Phd, Andrew T. Kaczynski Ph.D., Caroline Rudisill Ph.D., Msc, Ye Sil Kim Phd, Jasmin Parker-Brown, Kelsey R. Day

Faculty Publications

Churches hold promise for reaching populations with high rates of chronic disease, yet few faith-based large-scale implementation studies exist. The study purpose was to examine 12-month implementation outcomes and associated Consolidated Framework for Implementation Research (CFIR) constructs after converting in-person training to online for an evidence-based intervention designed to improve church organizational practices related to physical activity (PA) and healthy eating (HE). US churches recruited from 2020 to 2022 participated in eight online lessons prior to implementation. Each church’s coordinator completed an online baseline and 12-month survey assessing church practices for PA/HE components targeted in the Faith, Activity, and Nutrition …

Storytelling For Brand Awareness On Instagram: The Case Of Agavilab In The Biotechnology Sector, Oriell Annahlka, Anisa Diniati

JURNAL KOMUNIKASI INDONESIA

Brands, including AGAVILab, have implemented an Instagram content management strategy to address the challenges of building brand awareness, which is particularly important for startups not yet well-known to the public. Therefore, the company needs to enhance its efforts to create brand awareness, which is crucial for consumers when choosing products. As a startup that provides biotechnology research materials, AGAVILab is not yet well-known to the public. Therefore, the company needs to enhance its efforts to create brand awareness, which is crucial for consumers when choosing products. This research aims to describe how AGAVILab manages its Instagram content to build brand …