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Toward More Challenge-Engaging Stem Students: A Narrative Inquiry Into Student Persistence In The Face Of Failure, Stephanie R. Fahey Aug 2025

Toward More Challenge-Engaging Stem Students: A Narrative Inquiry Into Student Persistence In The Face Of Failure, Stephanie R. Fahey

Educational Leadership & Workforce Development Theses & Dissertations

Science, Technology, Engineering, and Mathematics (STEM) postsecondary graduates greatly contribute to advances in technology and research, and STEM fields promise graduates careers with positive long-term outcomes. Many postsecondary students initially choose STEM majors; however, less than half of those students graduate with a STEM degree. High STEM attrition is a problem that continues to vex educators and researchers. One attributable factor to high STEM attrition is students adversely reacting to initial academic failure in challenging STEM educational contexts. However, there are a lack of studies that investigate the individual experiences of students who persist despite academic failure to better understand …


Drinking To Compensate: Expanding Upon The Motivational Model Of Alcohol Use, Douglas J. Glenn Aug 2025

Drinking To Compensate: Expanding Upon The Motivational Model Of Alcohol Use, Douglas J. Glenn

Psychology Theses & Dissertations

The motivational model of alcohol use identifies four key drinking motives – coping, conformity, social, and enhancement – as important proximal antecedents of problematic drinking. However, applications of this model have been inconsistent in explaining drinking outcomes. Specifically, it is unclear under which conditions each drinking motive can be a risky or benign indicator of drinking behaviors. The current study theorized that a problematic drinking to compensate behavior could emerge across all drinking motives when alcohol is used to counteract a psychosocial (i.e., nondrinking) deficit. It was hypothesized, at the cross-sectional and daily level, that the associations between each drinking …


Practicing In The Laboratories Of Democracy: An Interpretive Phenomenological Analysis Of How Political Science Faculty Use Simulations With Community College Students, James Stewart Shifflett Aug 2025

Practicing In The Laboratories Of Democracy: An Interpretive Phenomenological Analysis Of How Political Science Faculty Use Simulations With Community College Students, James Stewart Shifflett

STEMPS Theses & Dissertations

Political science faculty members have often used simulations to promote civic engagement and build political efficacy in students. However, the use of political simulations with community college students has not been studied as extensively as it has with their four-year counterparts. Through the interpretive phenomenological analysis (IPA) methodology, this study examined the experiences of nine political science faculty members who use simulations with community college students to understand how instructional designers might better support their civic engagement and design efforts. Faculty members who participated in the study use simulations as constructive social interactions; as comprehensive learning experiences integrating preparation, facilitation …


“We Are Trans, But We’Re Not Transitional”: Exploring Safety, Place, And Space In The Lives Of Transgender Individuals In Southeastern Virginia, Susana Avalos Aug 2025

“We Are Trans, But We’Re Not Transitional”: Exploring Safety, Place, And Space In The Lives Of Transgender Individuals In Southeastern Virginia, Susana Avalos

Sociology & Criminal Justice Theses & Dissertations

In general, little research exists on trans people’s spatial experiences despite space being highly relevant to their experiences of violence and perceptions of safety. To date, two criminological studies have examined LGBTQ people’s fear of crime in relation to public or private places and spaces. This is in stark contrast to the sizable place and space literature on cisgender men and women. These topics from the perspectives of trans people are underexplored primarily because most criminological research has historically upheld binarized understandings of gender. Safety should not be privileged or limited to certain groups, individuals, or spaces. Instead, safety should …


Exploring The Relationship Between Cannabis Use Motives And Readiness To Change Among Young Adult College Students, Emma Kathryn Rawls Aug 2025

Exploring The Relationship Between Cannabis Use Motives And Readiness To Change Among Young Adult College Students, Emma Kathryn Rawls

Psychology Theses & Dissertations

Cannabis use among young adult college students has risen steadily over the past decade, raising concerns about the associated health, academic, and psychological consequences. While cannabis use motives and readiness to change have each been linked to use patterns and outcomes, limited research has examined how these factors interact. The current study investigated whether readiness to change, based on the Transtheoretical Model (TTM), moderates the relationship between cannabis use motives and cannabis-related consequences as well as past-30-day use frequency. A sample of 100 college students 18-25 years old (Mage = 20.08, SD = 2.12; 67% female; 55.0% Black or …


Two Essays On The Role Of Anthropomorphism In Consumer Behavior, Faegheh (Faa) Taheran Aug 2025

Two Essays On The Role Of Anthropomorphism In Consumer Behavior, Faegheh (Faa) Taheran

Theses and Dissertations in Business Administration

The first essay of this dissertation investigates the contradictory findings on the relationship between anthropomorphism and self-control by focusing on how everyday anthropomorphized objects, rather than the products being used for consumption, influence consumer behavior. While previous studies have shown that using anthropomorphized products may decrease consumers’ self-control, this paper examines how unrelated [to consumption] anthropomorphized objects in a consumer’s environment—such as a water bottle with a humanlike face—can evoke a sense of social presence, increasing consumers’ perceptions that they are being negatively evaluated. Drawing on mind perception theory, I propose that this fear of negative evaluation can enhance self-control. …


Persistence And Completion Rates Of Community College Students: The Impact Of Receptivity To Social Engagement Scores Compared To Recorded Cocurricular Activity, Nancy Wagner Boylan Aug 2025

Persistence And Completion Rates Of Community College Students: The Impact Of Receptivity To Social Engagement Scores Compared To Recorded Cocurricular Activity, Nancy Wagner Boylan

Educational Leadership & Workforce Development Theses & Dissertations

This study examined the relationship between Ruffalo Noel Levitz College Student Inventory Receptivity to Social Engagement scores and the persistence and completion of community college students. The Ruffalo Levitz College Student Inventory assesses student receptivity to institutional support services. Receptivity scores indicate a student's willingness to accept help in areas such as academic support and social engagement as well as career and financial guidance.

This research explored the impact of documented cocurricular involvement, measured through student activities indicators, on persistence and completion outcomes. Using ex post facto data and binary logistic regression analyses, the research focused on three populations at …


Systems Statistical Engineering – Hierarchical Fuzzy Constraint Propagation, Hengameh Fakhravar Aug 2025

Systems Statistical Engineering – Hierarchical Fuzzy Constraint Propagation, Hengameh Fakhravar

Engineering Management & Systems Engineering Theses & Dissertations

Driven by the growing need in the 21st century for integrating rigorous statistical analysis into engineering research, there is a movement to develop an integrated statistical engineering science within statistics and quality communities (Hoerl & Snee, 2010; Anderson-Cook et al., 2012). Systems Statistical Engineering research seeks to integrate the Causal Bayesian hierarchical modeling (Pearl, 2009) and cybernetic control theory within Beer’s Viable System Model (1972, 1979, 1985) and the Complex Systems Governance framework (Keating, 2014; Keating & Katina, 2015, 2016) to produce multivariate systemic models for robust dynamic systems mission performance. Cotter & Quigley (2018) set forth the Bayesian systemic …


A Focused Ethnography: Mental Health Therapists In Pediatric Integrated Care, Melanie Agustin Aug 2025

A Focused Ethnography: Mental Health Therapists In Pediatric Integrated Care, Melanie Agustin

Counseling & Human Services Theses & Dissertations

The scope of practice for Licensed Professional Counselors (LPCs) and counseling residents (LPC-R) in integrated behavioral health (IBH) settings is grounded in accredited, theory-informed education and training. The benefits of IBH models are well-documented, however there is limited research that addresses how counselors develop professionally and clinically function, while navigating within pediatric inpatient environments. This qualitative dissertation used a focused ethnographic design to explore the lived experiences of ten purposively sampled counselors (n = 10) through demographic surveys, field observation, and semi-structured interviews. Reflexive journaling bracketed researcher bias, and thematic analysis, supported by NVivo and new member checking, guided interpretation. …


The Psychological Constructs Of International Graduate Students Transitioning To A University In America: A Thematic Analysis, Umadevi Ramesh Aug 2025

The Psychological Constructs Of International Graduate Students Transitioning To A University In America: A Thematic Analysis, Umadevi Ramesh

Doctoral Dissertations

This dissertation employed a qualitative analysis methodology to explore the experiences of first-time international graduate students during their transition to university, focusing on initial adjustment, perceived support, perceived discrimination, and mental well-being. Previous studies about international student experience have mainly focused on undergraduate students. Furthermore, few have examined the initial transition period to university and factors involved in both positively and negatively impacting students’ adjustment process as well as overall psychological well-being. Nine participants qualified for inclusion in the present study and participated in semi-structured interviews, which the researcher analyzed using a thematic analysis framework. Participants expressed a strong need …


Adaptations To Family-Based Treatment For Medicaid-Insured Adolescents With Anorexia Nervosa, Renee Borges Aug 2025

Adaptations To Family-Based Treatment For Medicaid-Insured Adolescents With Anorexia Nervosa, Renee Borges

Doctoral Dissertations

Background: Family-based treatment (FBT) is the leading intervention for adolescents with anorexia nervosa (AN), however it is under researched in socioeconomically disadvantaged and racially diverse youth.

Methods: Semi-structured interviews were completed with ten FBT clinicians who practice in publicly-funded settings. Interview questions were focused on implementation challenges, overall acceptability and appropriateness of FBT, and naturally-occurring treatment adaptations.

Results: Content analysis revealed common themes relating to the implementation of FBT in publicly-funded, community-based settings: acceptability and appropriateness, complexity and learnability, perceived core components of FBT, cultural adaptations, socioeconomic factors, logistical considerations, organizational and systemic barriers, training acceptability, participant’s self-efficacy, and telehealth …


Inclusion, Diversity, Equity, And Access Annual Report, Fiscal Year 2025, April Anderson-Zorn, Emily Baldoni, Karmine Beecroft, Chad E. Buckley, Susan Franzen, Tom Hardy, Ellie Harman, Laura Killingsworth, Heather Koopmans, Maddi Loiselle, Joshua Newport, Ryan Peters, Seth Peterson, Lindsey Skaggs, Caitlin Stewart, Maria Tudela, Eric Willey, Angela Yon Aug 2025

Inclusion, Diversity, Equity, And Access Annual Report, Fiscal Year 2025, April Anderson-Zorn, Emily Baldoni, Karmine Beecroft, Chad E. Buckley, Susan Franzen, Tom Hardy, Ellie Harman, Laura Killingsworth, Heather Koopmans, Maddi Loiselle, Joshua Newport, Ryan Peters, Seth Peterson, Lindsey Skaggs, Caitlin Stewart, Maria Tudela, Eric Willey, Angela Yon

Reports and White Papers - Milner Library

Report of Milner Library's activities and initiatives related to Inclusion, Diversity, Equity, and Access in Fiscal Year 2025. Compiled by the IDEA Committee.


Optimization Of Mhealth Behavioral Interventions For Patients With Chronic Lymphocytic Leukemia: The Health4cll Study, Che Young Lee, Max J Gordon, Melissa M Markofski, Emily C Lavoy, Susan K Peterson, Liang Li, Sara Fares, Miranda Baum, Margaret Pace, Danielle Walsh, Alessandra Ferrajoli, Karen Basen-Engquist Aug 2025

Optimization Of Mhealth Behavioral Interventions For Patients With Chronic Lymphocytic Leukemia: The Health4cll Study, Che Young Lee, Max J Gordon, Melissa M Markofski, Emily C Lavoy, Susan K Peterson, Liang Li, Sara Fares, Miranda Baum, Margaret Pace, Danielle Walsh, Alessandra Ferrajoli, Karen Basen-Engquist

Faculty, Staff and Student Publications

Purpose: This pilot study of a diet and physical activity intervention (HEALTH4CLL) was conducted to reduce fatigue and improve physical function (PF) in patients with chronic lymphocytic leukemia (CLL).

Methods: The HEALTH4CLL study used a randomized factorial design based on the multiphase optimization strategy (MOST). Patients received diet, exercise, and body weight management instructional materials plus a Fitbit and were randomized to undergo one of 16 combinations of 4 evidence-based mHealth intervention strategies over 16 weeks. Patients' fatigue, PF, health-related quality of life, behavior changes, and program satisfaction and retention were assessed. Paired t-tests were used to examine changes in …


Language Barriers In Accessing Healthcare Services For Refugees In The United States, Sadaf Khuram Aug 2025

Language Barriers In Accessing Healthcare Services For Refugees In The United States, Sadaf Khuram

Communication & Theatre Arts Theses

Accessing healthcare is a pivotal aspect of refugees' integration into their host countries and significantly impacts their long-term health outcomes. The literature emphasizes the critical role of language proficiency in overcoming communication barriers within healthcare settings. This thesis, however, challenges the assumption that addressing language barriers alone is universally sufficient. It argues that the importance of language solutions is context-dependent, varying with the design of healthcare systems and the diverse needs and backgrounds of refugees. In some cases, focusing primarily on language barriers can divert resources from other critical areas, particularly when healthcare facilities have limited capacities or when services …


The Inside Scoop: Elucidating The Three-Way Relationship Between Schistosoma Mansoni, The Gut, And Vaccines, Mariam A. Mhanna Aug 2025

The Inside Scoop: Elucidating The Three-Way Relationship Between Schistosoma Mansoni, The Gut, And Vaccines, Mariam A. Mhanna

Biomedical Sciences Theses & Dissertations

Schistosomiasis is a neglected tropical disease that affects over 250 million people worldwide. This blood fluke infection burdens communities and areas with limited to no access to clean fresh water. When a host is exposed to cercariae, the infectious agent, in a body of water, it matures in the host’s circulation into adult female and male worms. Copulated adult worms migrate to the mesentery, in the case of Schistosoma mansoni, and produce eggs that can cross the intestinal barrier and get excreted in the feces to continue the lifecycle. The effects of S. mansoni infection on the host …


Service With A Smile Or Salesperson Mirroring? Understanding The Flow Of Emotional Contagion In Sales Encounters, Vinh Quoc Trong Luong Aug 2025

Service With A Smile Or Salesperson Mirroring? Understanding The Flow Of Emotional Contagion In Sales Encounters, Vinh Quoc Trong Luong

Theses and Dissertations in Business Administration

This study examines the directionality of emotional contagion in sales interactions, addressing a critical gap in understanding whether emotions flow primarily from the salesperson to the customer, from the customer to the salesperson, or bidirectionally. While prior research emphasizes customer-driven emotional flow or bidirectional alignment, this study challenges these assumptions by employing categorical Cross-Recurrence Quantification Analysis (CRQA) to assess temporal emotional synchronization in sales dialogues. Leveraging automated sentiment analysis and multi-agent AI evaluation for performance metrics, the research analyzes 166 sales interactions to quantify emotional influence dynamics. Results reveal that salespeople predominantly lead emotional exchanges, exhibiting stronger and more stable …


Investigating The Effects Of Drinking Environments On Alcohol Protective Behavioral Strategy Use, Perceived Self-Efficacy, And Perceived Effectiveness Through Experimental Vignette Design, Skyler Hoover Aug 2025

Investigating The Effects Of Drinking Environments On Alcohol Protective Behavioral Strategy Use, Perceived Self-Efficacy, And Perceived Effectiveness Through Experimental Vignette Design, Skyler Hoover

Dissertations

Derived from a Social Cognitive Theory framework (Bandura, 1986), the aim of this study was to assess the impact of different drinking environments on college students’ expected use of alcohol protective behavioral strategies, perceived effectiveness of those strategies, and perceived self-efficacy to use them. To accomplish this, we sought out to create and employ experimental vignettes consisting of a bar/club or party drinking environment in a two-part study. Study one aimed to pilot test the vignettes prior to their use in study two, whose aim was to test our initial hypotheses. Both analytic samples were recruited from a nationwide participant …


Formation Of Inclusive Competence Of Future Special Education Teachers, Gulbanu Ashimkhanova, Akbota Autaeva, Anar Rakhmetova, Gulmira Tussupbekova, Kanat Sadykov Aug 2025

Formation Of Inclusive Competence Of Future Special Education Teachers, Gulbanu Ashimkhanova, Akbota Autaeva, Anar Rakhmetova, Gulmira Tussupbekova, Kanat Sadykov

Higher Learning Research Communications

Objectives: This study aims to explore the phenomenon of inclusive competence as an integral trait of today’s educators.

Methods: The scientific research involved surveying students from pedagogical universities as well as using methods of analysis and synthesis, generalization, systematization, comparison, and classification.

Results: The concept of inclusive competence is understood as the degree of skills and knowledge required to fulfil pedagogical responsibilities within an inclusive educational environment. Key elements of inclusive competence, such as cognitive, motivational, reflexive, and operational components, have been identified and have the following functions:

  • · Cognitive elements enable teachers to develop a comprehensive understanding of pedagogical …


Associative Coding Of Conditioned Fear In The Thalamic Nucleus Reuniens In Rodents And Humans, Tuğçe Tuna, Michael S Totty, Muhammad Badarnee, Flávio Afonso Gonçalves Mourão, Shaun Peters, Mohammad R Milad, Stephen Maren Aug 2025

Associative Coding Of Conditioned Fear In The Thalamic Nucleus Reuniens In Rodents And Humans, Tuğçe Tuna, Michael S Totty, Muhammad Badarnee, Flávio Afonso Gonçalves Mourão, Shaun Peters, Mohammad R Milad, Stephen Maren

Faculty, Staff and Student Publications

The nucleus reuniens (RE) is a midline thalamic structure interconnecting the medial prefrontal cortex (mPFC) and the hippocampus (HPC). Recent work in both rodents and humans implicates the RE in the adaptive regulation of emotional memories, including the suppression of learned fear. However, the neural correlates of aversive learning in the RE of rodents and humans remain unclear. To address this, we recorded RE activity in humans (BOLD fMRI) and rats (fiber photometry) during Pavlovian fear conditioning and extinction. In both rats and humans, we found that conditioned stimulus (CS)-evoked activity in RE reflects the associative value of the CS. …


Phase 1 Clinical Trial Of ¡Iniciando! La Adultez: A Culturally Tailored Intervention For Transitioning Latino Young Adults With Autism, Antonio F. Pagán, Ana Esparza, Ana C. Ramirez, Miriam Ortiz, Linda Hernandez, Mary Beth Morgan, Geohanna Noel, Alejandro L. Pagán, Jada Salas, Cecilia Montiel-Nava Aug 2025

Phase 1 Clinical Trial Of ¡Iniciando! La Adultez: A Culturally Tailored Intervention For Transitioning Latino Young Adults With Autism, Antonio F. Pagán, Ana Esparza, Ana C. Ramirez, Miriam Ortiz, Linda Hernandez, Mary Beth Morgan, Geohanna Noel, Alejandro L. Pagán, Jada Salas, Cecilia Montiel-Nava

Psychological Science Faculty Publications

This Phase 1 clinical trial evaluated ¡Iniciando! la Adultez, a culturally adapted intervention for Latino autistic young adults (n = 56) and their parents (n = 63). Young adults showed significant post-treatment improvements on measures of social responsiveness (SRS-2), adaptive behavior (ABAS-3), executive functioning (BRIEF-A), quality of life (WHOQOL-BREF), transition readiness (TRS-A), coping self-efficacy (CSES), and emotion regulation (DERS-SF). Parents reported significant improvements in their perceptions of their child’s social responsiveness, adaptive behavior, and executive functioning, as well as increased transition readiness ratings. Notably, parents evinced a significant decrease in acculturative stress (RASI) and depressive symptoms (PHQ-9), however, …


Behaviour Change Design For Reducing Plastic Usage By Perceived Similarity Nudge, Quentin Ehkirch, Ferdi Raharja, Udari Samaranayake, Ken Ichi Sawai, Akane Matsumae Aug 2025

Behaviour Change Design For Reducing Plastic Usage By Perceived Similarity Nudge, Quentin Ehkirch, Ferdi Raharja, Udari Samaranayake, Ken Ichi Sawai, Akane Matsumae

Research outputs 2022 to 2026

This study explores the influence of perceived similarity on pro-environmental behavior, focusing on plastic reduction. Participants' daily plastic use and reduction were tracked over 30 days via online chat software, with controlled nudges from an agent. Each group included two examinees and one agent. Behavioral data were analyzed to evaluate predictability from various perspectives and its relationship with behavioral change. Results showed significant differences in predictability based on perceived similarity, particularly during the first 10 days. Furthermore, nudges, consumption levels, and behavioral changes significantly affected predictability within the first 20 days. These findings contribute to understanding how perceived similarity can …


The Silent Grief Of Grandmothers After An Out-Of-Order Death—An Interpretative Phenomenological Analysis, Jordan Robertson, Elizabeth Cutrer, Paul Caldarella, Jeremy B. Yorgason, Terrell Young, Erjola Gjini, Sarah Stuart, Savannah Tueller Aug 2025

The Silent Grief Of Grandmothers After An Out-Of-Order Death—An Interpretative Phenomenological Analysis, Jordan Robertson, Elizabeth Cutrer, Paul Caldarella, Jeremy B. Yorgason, Terrell Young, Erjola Gjini, Sarah Stuart, Savannah Tueller

Faculty Publications

This study delves into the lived experiences of grandmothers grappling with grief following the “out-of-order” death of a child, child-in-law, or grandchild, using an Interpretative Phenomenological Analysis grounded in the Dual Process Model-Revised. With 70% of U.S. adults over 65 being grandparents, the research highlights their often-invisible role as both grievers and caregivers amid family loss. Findings reveal three key themes: navigating personal grief, intergenerational support dynamics, and reconstructing family identity. Grandmothers oscillate between loss-oriented and restoration-oriented coping, with grief intensity varying by relational proximity—most profound when losing their own child. They provide emotional and practical support to surviving grandchildren, …


Understanding The Role Of Sports Injury Management By Australian Osteopaths: A Cross Sectional Survey Of 992 Practitioners, Brett Vaughan, Jon Adams, Wenbo Peng, Lauren V. Fortington, Michael Fleischmann, Kylie Fitzgerald, Amie Steel, David Sibritt Aug 2025

Understanding The Role Of Sports Injury Management By Australian Osteopaths: A Cross Sectional Survey Of 992 Practitioners, Brett Vaughan, Jon Adams, Wenbo Peng, Lauren V. Fortington, Michael Fleischmann, Kylie Fitzgerald, Amie Steel, David Sibritt

Research outputs 2022 to 2026

Sport-related injuries are common presentations to primary care and hospital settings. Australian osteopaths practice mainly in private clinical settings in which the frequency of sport-related injury presentations, and how these injuries are managed, is unknown. The objective of the study was to describe the demographic, practice, and clinical management characteristics of Australian osteopaths who report often treating sport-related injuries. The study is a secondary analysis of data derived from the Australian osteopathy practice-based research network. Respondents indicated the frequency treating sports-related injuries in addition to other demographic, practice, and patient management characteristics. Backward logistic regression identified significant characteristics associated with …


Changing The Perceived Pain Intensity In Populations With Spinal Cord Injury And With Health Disparities (Happiness): Protocol For A Feasibility Study, Ann Van De Winckel, Lin Zhang, Leslie R. Morse, Brianna Woodliff, Gladys Maestre, Kelsey Baker Aug 2025

Changing The Perceived Pain Intensity In Populations With Spinal Cord Injury And With Health Disparities (Happiness): Protocol For A Feasibility Study, Ann Van De Winckel, Lin Zhang, Leslie R. Morse, Brianna Woodliff, Gladys Maestre, Kelsey Baker

School of Medicine Publications

Background: Chronic neuropathic pain affects 69% of adults with spinal cord injury (SCI). Medication, as a primary treatment, has insufficient benefits and significant risks for addiction and adverse effects. Of the available mind and body approaches, Qigong is the most accessible for adults with SCI, with evidence for effectiveness in reducing pain. Still, there is insufficient evidence to make recommendations for adults with SCI. Thus, the feasibility of Qigong in SCI needs to be established. We previously demonstrated feasibility in a pilot study, in which 18 non-Hispanic White adults with SCI completed a 12-week remote Qigong program. However, three additional …


Lack Of Relationships Between Ketamine Treatment And Peripheral Neurotrophic And Inflammatory Factors In A Randomized Controlled Ketamine Trial Of Major Depressive Disorder, Manivel Rengasamy, Benjamin Panny, Zakary Hutchinson, Anna Marsland, Tessa Kovats, Angela Griffo, Crystal Spotts, Robert H Howland, Meredith L Wallace, Sanjay J Mathew, Shabnam Hossein, Rebecca B Price Aug 2025

Lack Of Relationships Between Ketamine Treatment And Peripheral Neurotrophic And Inflammatory Factors In A Randomized Controlled Ketamine Trial Of Major Depressive Disorder, Manivel Rengasamy, Benjamin Panny, Zakary Hutchinson, Anna Marsland, Tessa Kovats, Angela Griffo, Crystal Spotts, Robert H Howland, Meredith L Wallace, Sanjay J Mathew, Shabnam Hossein, Rebecca B Price

Staff and Researcher Publications

Background: Ketamine is a rapid-acting treatment for treatment-resistant depression (TRD), though mechanisms related to ketamine's effects remain unclear. Blood-based neurotrophic and inflammatory factors (NIFs; e.g., brain-derived neurotrophic factor, interleukin-6) have emerged as markers potentially linked to ketamine and ketamine treatment response.

Methods: In this secondary analysis of a randomized controlled trial (RCT), 133 adults with TRD received a single-dose infusion of ketamine (n = 89; 0.5 mg/kg) or saline (n = 44) and provided measures of peripheral blood NIF levels and depression severity across a five-day post-infusion period. Differences between ketamine and saline groups were examined for (1) NIF levels, …


A Place To Pause: Designing Ritual Space In The Domestic Realm, Elise Miller Aug 2025

A Place To Pause: Designing Ritual Space In The Domestic Realm, Elise Miller

Theses

Modern society in Western developed countries is focused on the rush and go, often leaving people feeling discombobulated from constant running around, task-oriented days and switching of roles one must play in different areas of their life, such as at home, work, socializing, parenting, etc. How can ritual bring a sense of calmness and order to lives of those on the go? Ritual studies are often only categorized under psychology, sociology, or religious studies. However, as industrial design encompasses human interaction with objects, often with an emotional quality, ritual can be studied more wholesomely with the added lens of industrial …


Identifying The Diagnostic Challenges And Indicators Of Orthostatic Tremor: Patient Perspectives, Diego Torresrussotto Aug 2025

Identifying The Diagnostic Challenges And Indicators Of Orthostatic Tremor: Patient Perspectives, Diego Torresrussotto

All Publications

Background: The diagnosis of orthostatic tremor (OT) is challenging because of its non-specific symptoms and a broad range of differential diagnosis, resulting in a complex and lengthy diagnostic journey.

Objective: The aim was to assess the diagnostic delay in OT and to identify key clinical indicators as reported by patients.

Methods: In 2019, the American OT community developed and distributed a web-based survey titled "Symptoms and Diagnosis of Orthostatic Tremor (OT)." The survey included questions on demographics, the diagnostic process, and symptomatology.

Results: An international cohort of 360 OT patients participated in the study, of which 147 with electromyography (EMG)-confirmed …


Implementation Outcomes Of A Patient Decision-Aid In A Diverse Population With Systemic Lupus Erythematosus In 15 Us Rheumatology Clinics, Jasvinder A Singh, Larry R Hearld, Seth Eisen, W Winn Chatham, Sonali Narain, Narender Annapureddy, Diane L Kamen, Kimberly Trotter, Vikas Majithia, Cathy Lee Ching, Zineb Aouhab, Swamy Venuturupalli, Daniel J Wallace, Rosalind Ramsey-Goldman, Alfred Kim, Maureen Mcmahon, S Sam Lim, Kalpana Bhairavarasu, Alexa Meara, Kenneth Kalunian, T Mark Beasley Aug 2025

Implementation Outcomes Of A Patient Decision-Aid In A Diverse Population With Systemic Lupus Erythematosus In 15 Us Rheumatology Clinics, Jasvinder A Singh, Larry R Hearld, Seth Eisen, W Winn Chatham, Sonali Narain, Narender Annapureddy, Diane L Kamen, Kimberly Trotter, Vikas Majithia, Cathy Lee Ching, Zineb Aouhab, Swamy Venuturupalli, Daniel J Wallace, Rosalind Ramsey-Goldman, Alfred Kim, Maureen Mcmahon, S Sam Lim, Kalpana Bhairavarasu, Alexa Meara, Kenneth Kalunian, T Mark Beasley

Faculty, Staff and Students Publications

Objective: The objective of this study was to examine the clinical outcomes during the implementation of a self-administered patient decision-aid (PtDA) for lupus.

Methods: We provided an effective computerized lupus PtDA in 15 rheumatology outpatient clinics 2019-2024 (including the COVID pandemic). We undertook Organizational Readiness to Implement Change Surveys (ORICs) and Team Learning and Psychological Safety Surveys (TLPSSs) at baseline. The primary study outcome objective measure, percent penetration/reach, was defined as the number of patients who viewed the lupus PtDA at the end of the study, divided by the total number of eligible patients (times 100). We used validated clinical …


Genetic Diversity And Expanded Phenotypes In Dystonia: Insights From Large-Scale Exome Sequencing, Mirja Thomsen, Fabian Ott, Sebastian Loens, Gamze Kilic-Berkmen, Ai Huey Tan, Shen-Yang Lim, Ebba Lohmann, Kaja M Schröder, Lea Ipsen, Lena A Nothacker, Linn Welzel, Alexandra S Rudnik, Frauke Hinrichs, Thorsten Odorfer, Kirsten E Zeuner, Friederike Schumann, Andrea A Kühn, Simone Zittel, Marius Moeller, Robert Pfister, Christoph Kamm, Anthony E Lang, Yi Wen Tay, Ana Luísa De Almeida Marcelino, Marie Vidailhet, Emmanuel Roze, Joel S Perlmutter, Jeanne S Feuerstein, Victor S C Fung, Florence Chang, Richard L Barbano, Steven Bellows, Aparna A Wagle Shukla, Alberto J Espay, Mark S Ledoux, Brian D Berman, Stephen Reich, Andres Deik, Andre Franke, Michael Wittig, Sören Franzenburg, Jens Volkmann, Norbert Brüggemann, H A Jinnah, Tobias Bäumer, Christine Klein, Hauke Busch, Katja Lohmann Aug 2025

Genetic Diversity And Expanded Phenotypes In Dystonia: Insights From Large-Scale Exome Sequencing, Mirja Thomsen, Fabian Ott, Sebastian Loens, Gamze Kilic-Berkmen, Ai Huey Tan, Shen-Yang Lim, Ebba Lohmann, Kaja M Schröder, Lea Ipsen, Lena A Nothacker, Linn Welzel, Alexandra S Rudnik, Frauke Hinrichs, Thorsten Odorfer, Kirsten E Zeuner, Friederike Schumann, Andrea A Kühn, Simone Zittel, Marius Moeller, Robert Pfister, Christoph Kamm, Anthony E Lang, Yi Wen Tay, Ana Luísa De Almeida Marcelino, Marie Vidailhet, Emmanuel Roze, Joel S Perlmutter, Jeanne S Feuerstein, Victor S C Fung, Florence Chang, Richard L Barbano, Steven Bellows, Aparna A Wagle Shukla, Alberto J Espay, Mark S Ledoux, Brian D Berman, Stephen Reich, Andres Deik, Andre Franke, Michael Wittig, Sören Franzenburg, Jens Volkmann, Norbert Brüggemann, H A Jinnah, Tobias Bäumer, Christine Klein, Hauke Busch, Katja Lohmann

Faculty, Staff and Students Publications

Objective: Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly complex.

Methods: Exome sequencing was conducted on 1924 genetically unsolved, mainly late-onset isolated dystonia patients, recruited primarily from two dystonia registries (DysTract and the Dystonia Coalition). Rare variants in genes previously linked to dystonia (n = 406) were examined, confirmed via Sanger sequencing, and analyzed for segregation when possible.

Results: We identified 137 distinct likely pathogenic/pathogenic variants (according to ACMG …


The Resilience Of The Human Lungs: Evolution, Smoke, And Disease, Joan B Soriano, Francesca Polverino Aug 2025

The Resilience Of The Human Lungs: Evolution, Smoke, And Disease, Joan B Soriano, Francesca Polverino

Faculty, Staff and Students Publications

No abstract provided.