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Precision Medicine Approach To Alzheimer’S Disease: Rationale And Implications, Dale E. Bredesen, Kat Toups, Ann Hathaway, Deborha Gordon, Henrianna Chung, Cyrus Raji, Alan Boyd, Benjamin D. Hill, Sharon Hausman-Cohen, Mouna Attarha, Won Jong Chwa, Alexei Kurakin, Michael Jarrett Jan 2023

Precision Medicine Approach To Alzheimer’S Disease: Rationale And Implications, Dale E. Bredesen, Kat Toups, Ann Hathaway, Deborha Gordon, Henrianna Chung, Cyrus Raji, Alan Boyd, Benjamin D. Hill, Sharon Hausman-Cohen, Mouna Attarha, Won Jong Chwa, Alexei Kurakin, Michael Jarrett

University Faculty and Staff Publications

The neurodegenerative disease field has enjoyed extremely limited success in the development of effective therapeutics. One potential reason is the lack of disease models that yield accurate predictions and optimal therapeutic targets. Standard clinical trials have pre-determined a single treatment modality, which may be unrelated to the primary drivers of neurodegeneration. Recent proof-of-concept clinical trials using a precision medicine approach suggest a new model of Alzheimer’s disease (AD) as a chronic innate encephalitis that creates a network insufficiency. Identifying and addressing the multiple potential contributors to cognitive decline for each patient may represent a more effective strategy. Here we review …


Felon Disenfranchisement: An Attack On Democracy In The United States, Katie Rodrigues Jan 2023

Felon Disenfranchisement: An Attack On Democracy In The United States, Katie Rodrigues

Student Publications and Presentations

No abstract provided.


Ben J. Atchison, Phd, Otrl, Faota Jan 2023

Ben J. Atchison, Phd, Otrl, Faota

OJOT Sponsor Profiles

No abstract provided.


Hostos Community College Academic Bulletin 2023-2024, Hostos Community College Jan 2023

Hostos Community College Academic Bulletin 2023-2024, Hostos Community College

College Bulletins

This is the official college catalog for 2023-2024. It contains course descriptions as well as information on degree programs, college resources and services, financial aid, admissions, and the academic calendar.


From Art To Propaganda: The Shift In The Concept Of The “Most Dead” In True Crime Literature, Hannah Mcconkey Jan 2023

From Art To Propaganda: The Shift In The Concept Of The “Most Dead” In True Crime Literature, Hannah Mcconkey

Dissertations and Theses @ UNI

This thesis studies the shift of the true crime genre from art to inescapable propaganda. This change is due, in part, to the politization of the genre by modern society. This includes the concept of the “most dead” seen within the true crime genre over the past several decades. The idea of the most dead is the belief that some victims of crimes are more or less dead depending on how marketable their demographic is. For instance, a blonde, Caucasian child would be considered the most dead while a woman of color in the sex work industry would be the …


Out In Education: A Qualitative Study Examining The Intersectionality And The Lived Out Experiences Of Prek–12 Lgbtq+ Educators, Landon Wood Jan 2023

Out In Education: A Qualitative Study Examining The Intersectionality And The Lived Out Experiences Of Prek–12 Lgbtq+ Educators, Landon Wood

Dissertations and Theses @ UNI

The role of a teacher is typically stereotyped as adhering to the status quo and societal norms, but LGBTQ+ educators and their intersecting identities have the power to interrupt the norm and move toward inclusion and advocacy for all, thus allowing the concepts of critical theory and queer theory to intersect. I have titled this merger queertical theory to discuss how LGBTQ+ teachers and their intersecting identities/nuanced perceptions and lived experiences can enact change in the field of education. Little research or information exists regarding how LGBTQ+ educators manage, handle, or even perceive intersectionality in their profession.

This qualitative study …


An Empirical Analysis Of The Link Between Built Environment And Safety In Chicago’S Transit Station Areas, Ahoura Zandiatashbar, Agustina Laurito Jan 2023

An Empirical Analysis Of The Link Between Built Environment And Safety In Chicago’S Transit Station Areas, Ahoura Zandiatashbar, Agustina Laurito

Faculty Research, Scholarly, and Creative Activity

Problem, research strategy, and findings: Considering that safety is a key environmental factor that promotes health, understanding the relationship between built environment features around transit station areas and crime may shed light on how to foster healthy communities. Yet, there is limited work that has examined how the combination of different built environment features around transit correlate with different crimes. We addressed this issue in this study using data from Chicago (IL). First, we used cluster analysis to classify stations in Chicago in a spectrum from transit-oriented development (TOD) to transit-adjacent development (TAD) categories depending on their built environment characteristics: …


In These Times Of Compassion When Conformity’S In Fashion: How Therapeutic Jurisprudence Can Root Out Bias, Limit Polarization And Support Vulnerable Persons In The Legal Process, Michael L. Perlin Jan 2023

In These Times Of Compassion When Conformity’S In Fashion: How Therapeutic Jurisprudence Can Root Out Bias, Limit Polarization And Support Vulnerable Persons In The Legal Process, Michael L. Perlin

Articles & Chapters

In this paper, I consider the extent to which caselaw has – either explicitly or implicitly – incorporated the precepts of therapeutic jurisprudence (TJ), a school of legal thought that focuses on the law’s influence on emotional life and psychological well-being, and that asks us to assess the actual impact of the law on people’s lives. Two of the core tenets of TJ in practice are commitments to dignity and to compassion. I conclude ultimately that, with these principles as touchstones, TJ can be an effective tool – perhaps the most effective tool - in rooting out bias, limiting polarization, …


Pass The Salt: Problem Resolution Lawyering Across The 21st Century Law Curriculum, Kris Franklin, F. Peter Phillips Jan 2023

Pass The Salt: Problem Resolution Lawyering Across The 21st Century Law Curriculum, Kris Franklin, F. Peter Phillips

Articles & Chapters

Legal education can help prepare law graduates to do that work. As an added bonus, doing so would in turn help law students understand and retain the subjects they study.

Law professors who teach alternative dispute resolution, lawyering skills, clinics, and sometimes traditional doctrinal courses, have all called for greater inclusion of dispute resolution in the law school curriculum. Some have urged the introduction of specific courses to prepare contemporary law students to work as problem resolvers. This Article builds on these and other calls for reform, but urges a genuine reconceptualization of the purposes of legal work. Framing lawyers’ …


Reflections On South Africa's First Black Chief Justice, Ismail Mahomed, Penelope Andrews Jan 2023

Reflections On South Africa's First Black Chief Justice, Ismail Mahomed, Penelope Andrews

Articles & Chapters

No abstract provided.


Labor Trafficking, Melynda Barnhart Jan 2023

Labor Trafficking, Melynda Barnhart

Articles & Chapters

No abstract provided.


Law Professors’ Conceptualization And Use Of Students’ Prior Knowledge And Experience In Developing Subject-Matter Understanding, Matthew Gewolb Jan 2023

Law Professors’ Conceptualization And Use Of Students’ Prior Knowledge And Experience In Developing Subject-Matter Understanding, Matthew Gewolb

Articles & Chapters

No abstract provided.


Racial Healing In The Church: The Usefulness Of The Interpersonal Process In Therapy Model, Winston Seegobin Jan 2023

Racial Healing In The Church: The Usefulness Of The Interpersonal Process In Therapy Model, Winston Seegobin

Faculty Publications - Doctor of Psychology (PsyD) Program

Racial disunity is a major challenge facing the Christian church. This article examines psychological factors that contribute to and maintain both racial disunity and racial unity through the lens of the Interpersonal Process in Therapy model (Sullivan, 1968; Teyber & Teyber, 2017). It looks at how early interpersonal relationships in childhood influence interpersonal relationships as adults and how the therapeutic relationship as a healing influence can be applied to racial healing as adults. Spiritual factors that contribute to and maintain racial disunity and racial unity are also discussed. Understanding that it is the relationship that heals, specific strategies such as …


Spiritual Well-Being Scale (Swbs): Measuring Spiritual Well-Being In International Contexts, Rodger K. Bufford, Raymond F. Paloutzian Jan 2023

Spiritual Well-Being Scale (Swbs): Measuring Spiritual Well-Being In International Contexts, Rodger K. Bufford, Raymond F. Paloutzian

Faculty Publications - Doctor of Psychology (PsyD) Program

The Spiritual Well-Being Scale (SWBS) is a 20-item measure of self-perceived spiritual health. Developed in the 1980s, it includes 2 subscales with 10 items each. Responses are made on a 6-point continuum from Strongly Disagree to Strongly Agree with no neutral point; 9 of the items are negatively worded to minimize response biases. The US samples show good internal consistency and test-retest reliability. Content validity was established in construction. Expected correlations with religion and spirituality indices, social and psychological measures, and physical functioning and demonstration of expected group differences support criterion validity. Factor analysis commonly shows 2 factors corresponding to …


Dynamic Risk As A Predictive Of Sexual Offense Treatment Outcomes, Kaylee Bartnes Ma, Jessica Cantley Ms, Jaycee Hallford Ms, Cameron Stumpf Ma, Nicholas Rodgers Ma, Rodger K. Bufford Jan 2023

Dynamic Risk As A Predictive Of Sexual Offense Treatment Outcomes, Kaylee Bartnes Ma, Jessica Cantley Ms, Jaycee Hallford Ms, Cameron Stumpf Ma, Nicholas Rodgers Ma, Rodger K. Bufford

Faculty Publications - Doctor of Psychology (PsyD) Program

Past Research  Those with higher criminogenic needs are more likely to recidivate (Andrews and Bonta, 1998).  Mandated therapy services have shown to have lower completion rates due to the lower intrinsic motivation (Rosenfeld, 1992).  Individuals mandated to treatment as a consequence of a previous sexual offense find engaging in treatment more challenging to complete as stigma, bias, social norms, and risk factors complicate and hinder their success (Olver et al., 2011). Current Study. We explored how dynamic risk factors differ between individuals who do and do not successfully complete mandated sexual offense treatment.


The Misattuned Music Industry: An Intersubjective Perspective On The Music Industry's Mental Health Crisis, Jonathan Fricke Jan 2023

The Misattuned Music Industry: An Intersubjective Perspective On The Music Industry's Mental Health Crisis, Jonathan Fricke

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Research shows that professional musicians tend to experience higher rates of mental health challenges compared to the general population. While there are a number of underlying factors and historical experiences that may help us to better understand these psychological struggles, I will be examining the relational system between musician and the music industry beginning at the time in which an amateur musician transitions to the professional realm. With this transition comes incredible demand and pressure from the industry. Professional musicians are at the mercy of grueling tour schedules where they spend months away from loved ones, must be "on" at …


Interactive Association Of Posttraumatic Stress Disorder, Apolipoprotein Ε4 Genotype, And Age On Cognitive Functioning, Karen A. Lawrence, Colton Rippey, Bianca Welikson, Robert H. Pietrzak, Thomas G. Adams Jr. Jan 2023

Interactive Association Of Posttraumatic Stress Disorder, Apolipoprotein Ε4 Genotype, And Age On Cognitive Functioning, Karen A. Lawrence, Colton Rippey, Bianca Welikson, Robert H. Pietrzak, Thomas G. Adams Jr.

Psychology Faculty Publications

Background: The ε4 allele of the apolipoprotein (APOE) gene and posttraumatic stress disorder (PTSD) are associated with cognitive deficits. Both associations may vary depending on age. No previous study has examined a possible three‐way interaction between APOE ε4, PTSD, and age on cognitive functioning.

Methods: Data were analyzed from 1244 European‐American U.S. military veterans who participated in the 2011 National Health and Resilience in Veterans Study (NHRVS). Analyses of covariance were used to examine the main effects and in- teractions of APOE ε4, PTSD, and age on learning/working memory (LWM) and attention/psychomotor (APM) performance.

Results: A significant three‐way interaction between …


Effect Of The Glucocorticoid Receptor Antagonist Pt150 On Acquisition And Escalation Of Fentanyl Self-Administration Following Early-Life Stress, Michael T. Bardo, Cassie M. Chandler, Emily D. Denehy, Benjamin A. Carper, Mark A. Prendergast, Tracy L. Nolen Jan 2023

Effect Of The Glucocorticoid Receptor Antagonist Pt150 On Acquisition And Escalation Of Fentanyl Self-Administration Following Early-Life Stress, Michael T. Bardo, Cassie M. Chandler, Emily D. Denehy, Benjamin A. Carper, Mark A. Prendergast, Tracy L. Nolen

Psychology Faculty Publications

There is comorbidity between posttraumatic stress disorder (PTSD) and opioid use disorder (OUD), perhaps because PTSD-like stressful experiences early in life alter the hypothalamic–pituitary-adrenal stress axis to increase the risk for OUD. The present study determined if the glucocorticoid receptor antagonist PT150 reduces the escalation of fentanyl intake in rats exposed to a “two-hit” model of early-life stress (isolation rearing and acute stress). Male and female rats were raised during adolescence in either isolated or social housing and then were given either a single acute stress (restraint and cold-water swim) or control treatment in young adulthood. Rats were then treated …


On Warrants & Waiting: Electronic Warrants & The Fourth Amendment, Tracy Hresko Pearl Jan 2023

On Warrants & Waiting: Electronic Warrants & The Fourth Amendment, Tracy Hresko Pearl

Faculty Articles

Police use of electronic warrant (“e-warrant”) technology has increased significantly in recent years. E-warrant technology allows law enforcement to submit, and magistrate judges to review and approve, warrant applications on computers, smartphones, and tablets, often without any direct communication. Police officers report that they favor e-warrants over their traditional counterparts because they save officers a significant amount of time in applying for warrants by eliminating the need to appear in-person before a magistrate. Legal scholars have almost uniformly praised e-warrant technology, as well, arguing that use of these systems will increase the number of warrants issued throughout the United States …


#Teacherquittok: A Content Analysis Of How Current And Former Teachers Navigate Attrition On Tiktok, Forrest J. Kaiser Jan 2023

#Teacherquittok: A Content Analysis Of How Current And Former Teachers Navigate Attrition On Tiktok, Forrest J. Kaiser

Education Faculty Publications and Presentations

The purpose of this study is to use thematic content analysis to examine conversations and factors most discussed by teachers centering on attrition using the TikTok social media platform. Social media offers teachers a way to connect with others and share their thoughts while maintaining a perceived level of professional distance from their workplace. This research will explore how teachers use social media to provide a window into their classroom, working conditions, and decisions to leave or stay. The study was guided by the following questions: (1) How are current and former teachers using the TikTok social media platform to …


Does Systematic Phonological Awareness In The Early Primary Grades Impact Student Learning Beyond Primary Grades, Renee Lyn Sorenson Jan 2023

Does Systematic Phonological Awareness In The Early Primary Grades Impact Student Learning Beyond Primary Grades, Renee Lyn Sorenson

Graduate Research Papers

This meta-analysis literature review was conducted by examining 24 scholarly articles to investigate the effects of systematic phonological awareness in the early primary grades and beyond. Children in these studies ranged from preschool, and in some studies continued to be monitored through fourth grade and beyond. The articles were gathered from APA Psycinfo and ERIC with search terms that included phonological awareness instruction in kindergarten aged students. The effects of these studies varied with the extent of the classroom’s rich phonological awareness and their intentional scaffolding.

This review was set up to investigate the correlation between phonological awareness and the …


Revisiting The Rainbow: Culturally Responsive Updates To A Standard Clinical Resource, Angela M. Dietsch, Richard Mocarski, Debra A. Hope, Nathan Woodruff, Miechelle Mckelvey Jan 2023

Revisiting The Rainbow: Culturally Responsive Updates To A Standard Clinical Resource, Angela M. Dietsch, Richard Mocarski, Debra A. Hope, Nathan Woodruff, Miechelle Mckelvey

Department of Special Education and Communication Disorders: Faculty Publications

Purpose

Cultural responsivity is essential for efficacious and affirming clinical relationships. This may be especially important with historically marginalized clients, such as transgender and gender-diverse (TGD) people seeking behaviorally based affirming communication services. We recommend modifications to standard tools for diagnostics and training that otherwise might undermine our efforts to create an inclusive and affirming environment.

Method

Modifications to the Rainbow Passage, a standardized paragraph utilized for eliciting speech samples in clinical settings, focused on nongendered terminology and the elimination of content with religious connotations.

Results

The recommended edits to the Rainbow Passage maintain similar length, cadence, and phonetic balance …


Brain Activity Associated With Taste Stimulation: A Mechanism For Neuroplastic Change?, Angela M. Dietsch, Ross M. Westemeyer, Douglas H. Schultz Jan 2023

Brain Activity Associated With Taste Stimulation: A Mechanism For Neuroplastic Change?, Angela M. Dietsch, Ross M. Westemeyer, Douglas H. Schultz

Department of Special Education and Communication Disorders: Faculty Publications

Purpose: Neuroplasticity may be enhanced by increasing brain activation and bloodflow in neural regions relevant to the target behavior.We administered precisely formulated and dosed taste stimuli to determine whether the associated brain activity patterns included areas that underlie swallowing control.

Methods: Five taste stimuli (unflavored, sour, sweet-sour, lemon, and orange suspensions) were administered in timing-regulated and temperature-controlled 3 mL doses via a customized pump/tubing system to 21 healthy adults during functional magnetic resonance imaging (fMRI). Whole-brain analyses of fMRI data assessed main effects of taste stimulation as well as differential effects of taste profile.

Results: Differences in …


Economic Values, Social Values And Cultural Animal Theory, Kevin Smith Jan 2023

Economic Values, Social Values And Cultural Animal Theory, Kevin Smith

Department of Political Science: Faculty Publications

Baumeister and Bushman (this issue: Psychological Inquiry 2023, vol. 34, no. 1) offer a cultural animal theory of partisan hostility (hereafter CAT) with the specific aim of explaining the root drivers of political conflict. CAT posits that competition for power revolves around oppositional worldviews reflecting preferences attached to the two primary objectives of all successful societies: amassing and distributing resources. Based on this premise CAT seeks not only to help explain the persistence of the themes motivating political conflict, but also to shed light on the underlying causes of growing levels affective polarization widely documented in the United States and …


Investigating Perceptions Of Out-Groups In Sport And United States Politics, Cody T. Havard, Elizabeth Theiss-Morse Jan 2023

Investigating Perceptions Of Out-Groups In Sport And United States Politics, Cody T. Havard, Elizabeth Theiss-Morse

Department of Political Science: Faculty Publications

The current study investigated how fans and supporters of sport teams and political parties in the United States viewed relevant out-groups and out-group members. Specifically, perceptions of rival sport teams and political parties were compared to determine how fans and supporters differed in their views and likely behaviors toward out-groups. Findings showed that sport fans reported more positive attitudes toward their favorite teams and more negative attitudes of the rival team than in politics. However, political supporters reported more negative perceptions and likely behaviors toward the out-group than fans of sport. Additional analysis revealed that the common in-group influenced perceptions. …


Honors In Practice, Volume 19, 2023 Jan 2023

Honors In Practice, Volume 19, 2023

Honors in Practice Online Archive

In This Issue:

Dedication to Kathleen B. King

Editor’s Introduction • Ada Long

2022 Presidential Address: The NCHC’s Inclusive Mission • Christina M. McIntyre

NCHC Article Reprinted from Inside Higher Ed: Can Honors Education Reach More Students? • Richard Badenhausen and James Buss

Essays:

Promoting Holistic Wellness in Honors Students through Peer Coaching • Leah Horton, Aaron Conrad, and Patricia J. Smith

Empowering Student Leadership amid Transition: Student-Centered Revision of First-Year Honors Peer Mentoring • Jacob R. Schlange and Tamy Burnett

Relational Peer Review Practices in the Honors Research Methods Classroom: Toward a Scaffolded and Multidisciplinary Model • Holly Riley …


Front Cover, Masthead, Contents, Call For Submissions, Dedication For Kathleen B. King Jan 2023

Front Cover, Masthead, Contents, Call For Submissions, Dedication For Kathleen B. King

Honors in Practice Online Archive

No abstract provided.


Epigenetics And Social Inequalities In Asthma And Allergy, Elizabeth S. Clausing, Cassidy J. Tomlinson, Amy L. Non Jan 2023

Epigenetics And Social Inequalities In Asthma And Allergy, Elizabeth S. Clausing, Cassidy J. Tomlinson, Amy L. Non

School of Global Integrative Studies: Faculty Publications

Respiratory illnesses, such as asthma and allergy disorders, are disproportionately more common among minority racial/ethnic groups and those of low socioeconomic status. In the United States, asthma prevalence and severity are highest among Puerto Ricans (19.2%), American Indians/Alaska Natives (13%), and Black Americans (12.7%) and higher in families living below the poverty threshold than among those living above it (11% vs 8%–9%).1 Many studies of asthma/allergy inequalities assume that genetic differences underlie racial/ethnic differences in these disorders, pointing to genetic ancestry differences between races, but most genetic variants fail to explain racial/ethnic differences and are usually studied only in …


Exploring The Role Of Environmental Features On Student Experience In The University Classroom With The Community Of Inquiry Framework, Heather R. Kennedy, Gloria E. Stafford Jan 2023

Exploring The Role Of Environmental Features On Student Experience In The University Classroom With The Community Of Inquiry Framework, Heather R. Kennedy, Gloria E. Stafford

Faculty Publications

An active learning classroom design recognizes the importance of students becoming engaged in their own learning. Using a mixed-methods approach, this study compared student-reported data (n = 219) and used the community of inquiry framework to evaluate the impact of environmental features on students’ experience. Students occupied traditional or active-learning classrooms, but the same course content was delivered by the same instructor. Findings indicate a preference for seating at tables versus fixed desks, appropriate personal space and sightlines to the teacher and projector screens, and gratification for forming social connections (i.e., social presence).


Empowering L2 Learners: The Role Of Relational Empathy In L2 Learning, Gabriela Olivares-Cuhat, Giovanni Zimotti Jan 2023

Empowering L2 Learners: The Role Of Relational Empathy In L2 Learning, Gabriela Olivares-Cuhat, Giovanni Zimotti

Faculty Publications

In this article, we explore the relevance of the concept of relational empathy to L2 learning. To this end, we first provide a short overview of the notion of empathy in second language acquisition (SLA). Then, we present ideas that gave rise to the introduction of relational empathy in the field of intercultural communication, along with potential benefits of taking this perspective in SLA. Next, we describe the post-method framework for L2 teaching as a strategy that is both well-suited for the fostering of relational empathy and is facilitated by the exercise of this approach. Following this lead, we explain …