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Octopus Optics: A Cross-Disciplinary Investigation Of Human Visual Bias In Narrative With Corresponding Writing Experiments Using Animal Focalisation, Stephanie Jane Cussans Moran

School of Art, Design and Architecture Theses

What is it like to be a human? If an octopus wrote an anthropology based on human depictions of octopuses then how might that reconfigure this existential question? This thesis addresses the posthuman problem of visual bias in animal storytelling practices by experimentally adopting the perspective of another highly visual animal - the octopus - through fiction. It seeks to question, find the edges, and feel the limitations of human representations of other animals and asks what doing so might say about our own naturalcultural perceptions and interpretations. In attending particularly to opticality in Anglophone storytelling, the thesis investigates ways …

Casting A Line To The Land: Narratologies Of Embodied Rituals And Connectivity To Place, Zoe Latham

School of Art, Design and Architecture Theses

This research argues for a re-conceptualisation and extension of place within architectural praxis that is reflective of broader discussions of meaning and environmental experience. This study examines the alignment between place and ritual theory as a way to better understand phenomenon that inform a greater connectivity between embodied and meaningful experiences with the environment. This will be explored through the act of fly fishing. Fly-fishing is relevant as the focus of the study owing in part to the author’s own experience as a fly angler. The relationship between the act of fly fishing, being part of nature and being in …

Performance Writing, Objects And Millennial Precarity: A Co-Authored Par Exploration Between Friends, Katheryn Owens

School of Art, Design and Architecture Theses

This practice-as-research project uses performance writing to understand, illustrate and work through aspects of millennial experience, with a specific interest in precarious housing and labour. For us, experiencing precarity means that fundamental aspects of what is required to experience what Lauren Berlant calls ‘a good life’ (including secure working contracts, renters’ rights, access to leisure time) are not being met. This leads to a feeling of ‘living on the edge’ (Ahmed, 2017: 238), which in turn prevents us from being able to imagine alternatives. This performance writing takes the form of scores, instructions, maps, walking, knitting, zines, and audio recordings. …

Towards The Validation Of Novel Cognitive And Physiological Indicators Of Affective State In Horses (Equus Caballus), Sarah Kappel

School of Biological and Marine Sciences Theses

Assessing animal emotions reliably is crucial for making accurate decisions about animal welfare, but subjective affective (emotional) states are inaccessible for direct measurement. We know that negative affect modulates attention in humans and some animals. The overarching aim of this thesis is to investigate if the preferential attention allocation towards certain information (i.e. attention bias, AB) could be a potential proxy measure of affective valence in horses. First, I provide an overview of the theoretical background to attention and AB by reviewing the literature on AB in humans and animals (Chapter 2). I examine which methodological aspects need consideration when …

Does Connectivity With Nature Alter Consumer Behaviour? Linking Ocean Connectedness And Consumer Views On Single-Use Packaging, Sohvi Katariina Nuojua

School of Biological and Marine Sciences Theses

Single-use packaging items constitute a large proportion of the plastic litter found in the marine environment. Consumer behaviour is a key contributor to the accumulation of this pollution in the environment. This thesis outlines correlational and experimental research on consumer responses to environmentally relevant qualities of single-use packaging. Furthermore, it considers a novel concept of ocean connectedness as a psychological moderator of consumer response. Studies 1 and 2 investigated consumer responses to recyclability of packaging as well as its raw material (plastic, glass, carton and aluminium) in undergraduate students and in a broader UK public sample. Ocean connectedness was assessed …

What Bothers Severe Asthma Patients Most? A Paired Patient–Clinician Study Across Seven European Countries, Ben Ainsworth, Eleanor Chatburn, Aruna T. Bansal, Olivia Fulton, Dominique Hamerlijnck, Courtney Coleman, Katrien Eger, Michael Hyland, Joshua Holmes, Liam Heaney, Vratislav Sedlák, Sabina Škrgat, Natalija Edelbaher, Brinke A Ten, Celeste Porsbjerg, Mina Gaga, Claudia Loureiro, Ratko Djukanovic, Emmanuelle Berret, Namhee Kwon

School of Psychology

Introduction Severe asthma is a complex, multidimensional disease. Optimal treatment, adherence and outcomes require shared decision-making, rooted in mutual understanding between patient and clinician. This study used a novel, patient-centred approach to examine the most bothersome aspects of severe asthma to patients, as seen from both perspectives in asthma registries. Methods Across seven countries, 126 patients with severe asthma completed an open-ended survey regarding most the bothersome aspect(s) of their asthma. Patients’ responses were linked with their treating clinician who also completed a free-text survey about each patient’s most bothersome aspect(s). Responses were coded using content analysis, and patient and …

Transition Theory And The Emotional Journey To Medical Educator Identity: A Qualitative Interview Study, J Browne, T Collett

Peninsula Medical School

Background. Medical academia is in crisis, with fewer people entering and growing concern at numbers leaving. While faculty development is often seen as part of the solution, there are significant issues with faculty not engaging with and resisting development opportunities. Lack of motivation may be linked to what might be called a ‘weak’ educator identity. We studied medical educators' experiences of career development to gain further insights into: how professional identity may develop; individuals' accompanying emotional responses to perceived identity change; and consideration of the accompanying temporal dimensions. Drawing on new materialist sociology, we explore medical educator identity formation in …

Preconception Care For People With Health Conditions: What Approaches Work, For Whom, And In What Circumstances? A Realist Review, Heather Hopper, Kerryn Husk, Kate Maslin, Bridie Kent, Amanda Wanner, Jill Shawe

School of Nursing and Midwifery

Preconception care for people with chronic health conditions is recommended in view of the implications for them and their offspring during pregnancy and beyond. This realist review of published and grey literature explored factors that explain why people seek or receive appropriate preconception counseling and why they engage in recommended health behavior change prior to pregnancy. Fifty-two studies contributed to phase one synthesis, and 38 studies provided explanations in phase two. Ten program theories were developed, explored, and refined through iterative discussion and coding. Causal explanations of the ways in which components of preconception care contribute to effective access to …

Analysis Of Fibroblast Growth Factor 14 (Fgf14) Structural Variants Reveals The Genetic Basis Of The Early Onset Nystagmus Locus Nys4 And Variable Ataxia, F Ceroni, D Osborne, S Clokie, Da Bax, Ej Cassidy, Mj Dunn, Cm Harris, Je Self, Nk Ragge

School of Psychology

AbstractNystagmus (involuntary, rhythmical eye movements) can arise due to sensory eye defects, in association with neurological disorders or as an isolated condition. We identified a family with early onset nystagmus and additional neurological features carrying a partial duplication of FGF14, a gene associated with spinocerebellar ataxia type 27 (SCA27) and episodic ataxia. Detailed eye movement analysis revealed oculomotor anomalies strikingly similar to those reported in a previously described four-generation family with early onset nystagmus and linkage to a region on chromosome 13q31.3-q33.1 (NYS4). Since FGF14 lies within NYS4, we revisited the original pedigree using whole genome sequencing, identifying a 161 …

Hydrocephalus: A Neuropsychological And Theoretical Primer, Tara Zaksaite, Catherine Loveday, Trudi Edginton, Hugo J. Spiers, Alastair D. Smith

School of Psychology

Hydrocephalus is a common neurological condition, the hallmark feature of which is an excess in production, or accumulation, of cerebrospinal fluid in the ventricles. Although it is associated with diffuse damage to paraventricular brain areas, patients are broadly typified by a particular pattern of cognitive impairments that include deficits in working memory, attention, and spatial abilities. There have, however, been relatively few neuropsychological accounts of the condition. Moreover, theories of the relationship between aetiology and impairment appear to have emerged in isolation of each other, and proffer fundamentally different accounts. In this primer, we aim to provide a comprehensive and …

Abnormal Thalamic Functional Connectivity Correlates With Cardiorespiratory Fitness And Physical Activity In Progressive Multiple Sclerosis, Francesco Romanò, Robert W. Motl, Paola Valsasina, Maria Pia Amato, Giampaolo Brichetto, Nicolò Bruschi, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Amber Salter, Brian M. Sandroff, Anthony Feinstein, Maria A. Rocca, Massimo Filippi

School of Health Professions

BackgroundAltered thalamic volumes and resting state (RS) functional connectivity (FC) might be associated with physical activity (PA) and cardiorespiratory fitness (CRF) in people with progressive multiple sclerosis (PMS).ObjectivesTo assess thalamic structural and functional alterations and investigate their correlations with PA/CRF levels in people with PMS.MethodsSeven-day accelerometry and cardiopulmonary exercise testing were used to assess PA/CRF levels in 91 persons with PMS. They underwent 3.0 T structural and RS fMRI acquisition with 37 age/sex-matched healthy controls (HC). Between-group comparisons of MRI measures and their correlations with PA/CRF variables were assessed.ResultsPMS people had lower volumes compared to HC (all p < 0.001). At corrected threshold, PMS showed decreased intra- and inter-thalamic RS FC, and increased RS FC between the thalamus and the hippocampus, bilaterally. At uncorrected threshold, decreased thalamic RS FC with caudate nucleus, cerebellum and anterior cingulate cortex (ACC), as well as increased thalamic RS FC with occipital regions, were also detected. Lower CRF, measured as peak oxygen consumption (VO2peak), correlated with lower white matter volume (r = 0.31, p = 0.03). Moreover, lower levels of light PA correlated with increased thalamic RS FC with the right hippocampus (r = − 0.3, p = 0.05).DiscussionPeople with PMS showed widespread brain atrophy, as well as pronounced intra-thalamic and thalamo-hippocampal RS FC abnormalities. White matter atrophy correlated with CRF, while increased thalamo-hippocampal RS FC was associated to worse PA levels. Thalamic RS FC might be used to monitor physical impairment and efficacy of rehabilitative and disease-modifying treatments in future studies.

Covid-19 And The Physio4fmd Trial: Impact, Mitigating Strategies And Analysis Plans, Louise Marston, Novere M Le, Federico Ricciardi, Irwin Nazareth, Alan Carson, Mark Edwards, Laura H. Goldstein, Jonathan Marsden, Hayley Noble, Markus Reuber, Jon Stone, Rachael M. Hunter, Glenn Nielsen

School of Health Professions

Introduction Functional motor disorder (FMD) is a common cause of disabling neurological symptoms such as weakness and tremor. Physio4FMD is a pragmatic, multicentre single blind randomised controlled trial to evaluate effectiveness and cost effectiveness of specialist physiotherapy for FMD. Like many other studies this trial was affected by the COVID-19 pandemic. Methods The planned statistical and health economics analyses for this trial are described, as well as the sensitivity analyses designed to assess the disruption caused by COVID-19. The trial treatment of at least 89 participants (33%) was disrupted due to the pandemic. To account for this, we have extended …

How To … Define Clinical Education Research Terminology: A Glossary, Gabrielle M. Finn, Ben Charmer, Oliver E. Burton, Aqua Asif, Matthew H.V. Byrne, Nicola Brennan, Megan E.L. Brown

Peninsula Medical School

Clinical education research (ClinEdR) utilises diverse terminology, which can lead to confusion. A common language is essential for enhancing impact. An expert panel drawn from various workstreams within the National Institute for Health and Care Research (NIHR) Incubator for Clinical Education Research was tasked with reviewing an initial list of terms for the development of a glossary of terms in the field of ClinEdR. The glossary was populated with terms, definitions and foundational papers by the authors and peer-reviewed for accuracy. The glossary of terms developed for ClinEdR should enable researchers to use a common language, promoting consistency and improving …

Motivational Support Intervention To Reduce Smoking And Increase Physical Activity In Smokers Not Ready To Quit: The Tars Rct, Adrian H. Taylor, Tom P. Thompson, Adam Streeter, Jade Chynoweth, Tristan Snowsill, Wendy Ingram, Michael Ussher, Paul Aveyard, Rachael L. Murray, Tess Harris, Colin Green, Jane Horrell, Lynne Callaghan, Colin J. Greaves, Lisa Price, Lucy Cartwright, Jonny Wilks, S Campbell, Dan Preece, Siobhan Creanor

Peninsula Medical School

No abstract provided.

Strategies Are Needed To Support People With Alcohol Use Disorder And Alcohol-Related Liver Disease To Take Part In Randomised Clinical Trials: Results From The Mirage Pilot Trial Of Functional Imagery Training, A Dhanda, V Allgar, J Andrade, L Callaghan, B Hudson, W Ingram, A King, V Lavers, J Lomax, A Mccune, C Musicha, R Parker, C Rollinson, S Creanor

Peninsula Medical School

No abstract provided.

The Importance Of Multimodal Play And Storytelling In Medtech For Children: A Case Study Of Co-Designing A Mixed Realities Play Kit To Prepare 4 To 10-Year-Olds For An Mri Scan, D Yamada-Rice, S Love, J Thompson, S Thompson, H Mcquillian

School of Art, Design and Architecture

This article examines the research and development of a mixed realities play-kit to prepare children for an MRI scan to be undertaken without the need for a General Anaesthetic. The kit uses three different types of play; augmented, virtual reality and physical to help children become familiar with the look of an MRI scanner, the noises it makes, the role of the radiographer, what to expect when they go to hospital and to practise staying still. We reflect on the initial multimodal research methods that were used to bring children into the first stages of the design and development process. …

Assessing The Association Between Overcrowding And Human Physiological Stress Response In Different Urban Contexts: A Case Study In Salzburg, Austria, Zhaoxi Zhang, Kristýna Měchurová, Bernd Resch, Prince Amegbor, Clive E. Sabel

School of Geography, Earth and Environmental Sciences

Overcrowding in densely populated urban areas is increasingly becoming an issue for mental health disorders. Yet, only few studies have examined the association between overcrowding in cities and physiological stress responses. Thus, this study employed wearable sensors (a wearable camera, an Empatica E4 wristband and a smartphone-based GPS) to assess the association between overcrowding and human physiological stress response in four types of urban contexts (green space, transit space, commercial space, and blue space). A case study with 26 participants was conducted in Salzburg, Austria. We used Mask R-CNN to detect elements related to overcrowding such as human crowds, sitting …

Mental Imagery Of Suicide And Non-Suicidal Self-Injury: A Meta-Analysis And Systematic Review, Hannah R. Lawrence, Emma G. Balkind, Julie L. Ji, Taylor A. Burke, Richard T. Liu

School of Psychology

Background The vast majority of research on, and clinical assessment of, cognitions related to suicide and non-suicidal self-injury (NSSI) has focused on verbal thoughts. And yet, mental imagery is more realistic and emotionally arousing than verbal thoughts. Methods We conducted a systematic review and meta-analysis documenting the prevalence of suicidal and NSSI mental imagery and describing the content and characteristics of suicidal and NSSI mental imagery, links between suicidal and NSSI mental imagery and suicidal and NSSI behavior, and how to intervene on suicidal and NSSI mental imagery. Studies published through December 17, 2022 were identified through a systematic search …

A Pragmatic, Multicentre, Double-Blind, Placebo-Controlled Randomised Trial To Assess The Safety, Clinical And Cost-Effectiveness Of Mirtazapine And Carbamazepine In People With Alzheimer’S Disease And Agitated Behaviours: The Hta-Symbad Trial, Sube Banerjee, Nicolas Farina, Catherine Henderson, Juliet High, Susan Stirling, Lee Shepstone, Julia Fountain, Clive Ballard, Peter Bentham, Alistair Burns, Chris Fox, Paul Francis, Robert Howard, Martin Knapp, Iracema Leroi, Gill Livingston, Ramin Nilforooshan, Shirley Nurock, John O’Brien, Annabel Price, Alan J. Thomas, Ann Marie Swart, Tanya Telling, Naji Tabet

Peninsula Medical School

No abstract provided.

The Nutritional Online Survey For Pregnancy Induced Sickness & Hyperemesis (Nourish) Study: Results From The First Trimester, Kate Maslin, Caitlin Dean, Jill Shawe

School of Nursing and Midwifery

Background:Hyperemesis gravidarum (HG) is severe pregnancy sickness,often leading to dehydration, weight loss and electrolyte disturbances. Little isknown about nutritional intake and its consequences in those affected. Theaim of this study was to explore thefirst trimester nutritional intake andclinical characteristics in those with severe sickness.Method:Recruitment was via the social media accounts of national pregnancycharities. The eligibility criteria were as follows: between 6 and 11 weekspregnant, age≥18 years and residing in the UK. Participants completed a self‐report online questionnaire including the Pregnancy Unique Quantification ofEmesis 24 (PUQE24) score and a 3‐day online diet diary. Groups werecompared by PUQE24 categories. Nutritional intakes were …

Unlocking Social Innovation In Xr For Healthcare In Coastal Communities, Alejandro Veliz Reyes, Marius N. Varga, Hannah Bradwell, Rory Baxter

School of Art, Design and Architecture

This position paper reconsiders the 'social' aspect of XR systems for healthcare, often developed following a 'problem-solution' approach that neglects sociocultural factors affecting their codesign and successful adoption. Focusing on coastal and rural communities, we review and present key principles to consider when codesigning XR systems with marginalised groups. Our work stems from two projects funded by UK Research & Innovation that aim to promote healthy ageing in coastal communities.

Investigating The Role Of Action-Contingent Expectancy Biases In Dysphoria-Linked Activity Engagement Behavioural Choice, Julie L. Ji, Colin Macleod

School of Psychology

Reduced tendency to engage in potentially rewarding activities is a hallmark of depression. The present study investigated the role of future expectancy biases in depression-linked behavioural choice, in participants varying in self-reported depression symptoms (dysphoria). A novel laboratory paradigm was developed to test the hypotheses that the degree to which higher dysphoria is associated with reduced tendency to engage in a potentially rewarding activity is dependent on the presence of negative biases in the expected outcomes of activity engagement. Specifically, two types of expectancy biases were distinguished: a) the expected likelihood of a negative rather than positive outcome, and b) …

Survey Of Parents Of Children With Intellectual Disabilities And/Or Autism Who Experience Chronic Constipation, James Rooney, Rebecca Hodge, Jade Smith, Kelly Vanstone, Richard Laugharne, Rohit Shankar

Peninsula Medical School

Background: Constipation is common in children with intellectual disabilities and/or autism, but poorly researched. This study looks to understand parental knowledge, attitudes and management practices towards constipation in children with intellectual disabilities and/or autism. Methods: A cross-sectional online survey developed with patient facing organisations was circulated to parents of children with intellectual disabilities and/or autism using an exponential and non-discriminatory snowballing method for recruitment. A smaller sample were purposively sampled for their in-depth experiences. Results: Of 68 responses, people were open to discussing constipation and knowledgeable about risk factors. In the qualitative interviews, of 15 parents, they wanted to be …

Review And Update Of The Health Of The Nation Outcome Scales For People With Learning Disabilities (Honos-Ld), Jon Painter, Nicola Adams, Barry Ingham, Michael James, Madiha Majid, Ashok Roy, Rohit Shankar, Mark Smith

Peninsula Medical School

Background: The Health of the Nation Outcomes Scales for people with Learning Disabilities (HoNOS-LD) is an 18-item measure which provides a structured and standardized approach to rating various clinical and psychosocial outcomes and has been in use nationally since 2002. Aims: To revise and improve the HoNOS-LD’s utility in contemporary intellectual disability (ID) services whilst retaining its original objectives and five-point severity ratings. Method: ID clinicians were invited to complete an online survey, rating each item on the existing measure for being fit for purpose, identifying issues and suggesting improvements based on their experience of using the HoNOS-LD in practice. …

Frontal Variant Alzheimer's Disease: A Systematic Narrative Synthesis, Sarah Salo

School of Psychology

BackgroundFrontal variant Alzheimer's disease (fvAD) is considered a rare form of Alzheimer's disease (AD) which may be misdiagnosed as behavioural variant frontotemporal dementia (bvFTD). The literature has tended to conflate behavioural and executive dysfunction in fvAD cohorts and uses both AD diagnostic criteria and bvFTD diagnostic criteria to classify fvAD cohorts. The primary aim of this narrative synthesis was to summarise neuropsychological findings in fvAD cohorts in the context of established AD pathology.MethodsEMBASE, PsycINFO, PROQUEST and MEDLINE databases were searched for studies eligible for inclusion. Studies with both neuropsychological and biomarker evidence were included in the final narrative synthesis.ResultsTen studies …

End-Of-Life Care In The Last Three Months Before Death In Older Patients With Cancer In Belgium: A Large Retrospective Cohort Study Using Data Linkage, Victoria Depoorter, Katrijn Vanschoenbeek, Lore Decoster, Geert Silversmit, Philip R. Debruyne, Inge De Groof, Dominique Bron, Frank Cornélis, Sylvie Luce, Christian Focan, Vincent Verschaeve, Gwenaëlle Debugne, Christine Langenaeken, Heidi Van Den Bulck, Jean Charles Goeminne, Wesley Teurfs, Guy Jerusalem, Dirk Schrijvers, Bénédicte Petit, Marika Rasschaert, Jean Philippe Praet, Katherine Vandenborre, Harlinde De Schutter, Koen Milisen, Johan Flamaing, Cindy Kenis, Freija Verdoodt, Hans Wildiers

School of Nursing and Midwifery

This study aims to describe end-of-life (EOL) care in older patients with cancer and investigate the association between geriatric assessment (GA) results and specialized palliative care (SPC) use. Older patients with a new cancer diagnosis (2009–2015) originally included in a previous multicentric study were selected if they died before the end of follow-up (2019). At the time of cancer diagnosis, patients underwent geriatric screening with Geriatric 8 (G8) followed by GA in case of a G8 score ≤14/17. These data were linked to the cancer registry and healthcare reimbursement data for follow-up. EOL care was assessed in the last three …

Nutritional Practices And Dietetic Provision In The Endometriosis Population, With A Focus On Functional Gut Symptoms, Komal Deepak Kumar, Bridie Appleby-Gunnill, Kate Maslin

School of Nursing and Midwifery

Background: Endometriosis is a common condition causing chronic pain, fatigue and gut symptoms. Research suggests that dietary changes may improve symptoms; however, evidence is lacking. The present study aimed to investigate the nutritional practices and needs of individuals with endometriosis (IWE) and the management of endometriosis by dietitians in the UK, focusing on gut symptoms. Methods: Two online questionnaires were distributed via social media: a survey of dietitians working with IWE and functional gut symptoms and a survey of IWE. Results: All respondents to the dietitian survey (n = 21) used the low fermentable oligosaccharides disaccharides monosaccharides and polyols (FODMAP) …

Incidence Of Injury And Illness Among Paediatric Team Usa Athletes Competing In The 2020 Tokyo And 2022 Beijing Olympic And Paralympic Games, Eric G Post, Travis Anderson, Jeffrey S Shilt, Eric L Dugan, Stephanie C Clark, Emily G Larson, Kayle E Noble-Taylor, David M Robinson, Amber T Donaldson, Jonathan T Finnoff, William M Adams

Faculty, Staff and Students Publications

OBJECTIVE: To describe the incidence of injuries and illnesses among paediatric Team USA athletes competing in the Tokyo 2020 Olympic and Paralympic Games, and the 2022 Beijing Olympic and Paralympic Games.

METHODS: An electronic medical record system documented all injuries and illnesses that occurred while competing in the four Games periods. Incidence (IR) with 95% CI per 1000 athlete days were calculated for both injuries and illnesses. Incidence rate ratios (IRR) were calculated to compare injury and illness rates based on age (paediatric vs non-paediatric) sex, Games period and sport type.

RESULTS: Two hundred paediatric athletes (age range, 15-21 years) …

Subcortical Functional Connectivity And Its Association With Walking Performance Following Deployment Related Mild Tbi, Mary R Newsome, Sarah L Martindale, Nicholas Davenport, Emily L Dennis, Marlene Diaz, Carrie Esopenko, Cooper Hodges, George R Jackson, Qisheng Liu, Kimbra Kenney, Andrew R Mayer, Jared A Rowland, Randall S Scheibel, Joel L Steinberg, Brian A Taylor, David F Tate, J Kent Werner, William C Walker, Elisabeth A Wilde

Faculty, Staff and Students Publications

INTRODUCTION: The relation between traumatic brain injury (TBI), its acute and chronic symptoms, and the potential for remote neurodegenerative disease is a priority for military research. Structural and functional connectivity (FC) of the basal ganglia, involved in motor tasks such as walking, are altered in some samples of Service Members and Veterans with TBI, but any behavioral implications are unclear and could further depend on the context in which the TBI occurred.

METHODS: In this study, FC from caudate and pallidum seeds was measured in Service Members and Veterans with a history of mild TBI that occurred during combat deployment, …

A Systematic Review And Meta-Analysis Of Long Term Physical And Mental Sequelae Of Covid-19 Pandemic: Call For Research Priority And Action, Na Zeng, Yi-Miao Zhao, Wei Yan, Chao Li, Qing-Dong Lu, Lin Liu, Shu-Yu Ni, Huan Mei, Kai Yuan, Le Shi, Peng Li, Teng-Teng Fan, Jun-Liang Yuan, Michael V Vitiello, Thomas Kosten, Alexandra L Kondratiuk, Hong-Qiang Sun, Xiang-Dong Tang, Mei-Yan Liu, Ajit Lalvani, Jie Shi, Yan-Ping Bao, Lin Lu

Faculty, Staff and Students Publications

The long-term physical and mental sequelae of COVID-19 are a growing public health concern, yet there is considerable uncertainty about their prevalence, persistence and predictors. We conducted a comprehensive, up-to-date meta-analysis of survivors' health consequences and sequelae for COVID-19. PubMed, Embase and the Cochrane Library were searched through Sep 30th, 2021. Observational studies that reported the prevalence of sequelae of COVID-19 were included. Two reviewers independently undertook the data extraction and quality assessment. Of the 36,625 records identified, a total of 151 studies were included involving 1,285,407 participants from thirty-two countries. At least one sequelae symptom occurred in 50.1% (95% …