Digital Commons Network^™

Worldwide Innovative Network Consortium: Building A Common Global Cancer Database., Farhood Farahnak, Wafik S El-Deiry, Yves A Lussier, Razelle Kurzrock, Shai Magidi, Catherine Bresson, Shirin A Enger, Jia Liu, Jair Bar, Jeremy L Warner, Tobias Meissner, Eitan Rubin, Jens Rueter, Himabindu Gaddipati, Mandar Kulkarni, Zhen Chen, Sewanti Limaye, Rachel Elsey, Brenda M Rubenstein, Anthony M Joshua, Humaid O Al-Shamsi, Khaled M Musallam, Fanny Wunder, Jacques Raynaud, Guy Berchem, Manon Gantenbein, Amal Al Omari, Said Dermime, Hikmat Abdel-Razeq, Pierre Saintigny, Andrés Cervantes, Roger R Reddel, Adel T Aref, Juan Martin-Liberal, Conxi Lázaro, David Cordero Romera, Marina Sekacheva, Raanan Berger, C S Pramesh, Ioana Berindan-Neagoe, Eugenia Girda, Alejandro Piris-Gimenez, Carol J Farhangfar, Mohammed E Salem, Rodrigo Dienstmann, Ramon Salazar, Naftali Z Frankel, Zachary Batist, Yuri Quintana, Gerald Batist

Faculty Research 2026

This review shares the ongoing work of the global Worldwide Innovative Network (WIN) Consortium for Precision Medicine to synthesize emerging cancer treatment data and to define the requirements for a common global cancer database that can truly support precision oncology. We performed a narrative review of emerging cancer treatment data, molecular profiling technologies, and existing clinicogenomic databases, focusing on how tumors are characterized, how subgroups are defined, and how demographic, lifestyle, and environmental factors are captured. The growth in molecular profiling technologies and the development of new targeted therapies are transforming cancer care. Tumors, regardless of tissue origin, are increasingly …

The Nature Of Human Trafficking Enterprises: Analysis Of U.S. And International Prosecutions--And The Path Forward, Jay Albanese

Dignity: A Journal of Analysis of Exploitation and Violence

The primary objective of this research is to develop a description and typology of the nature of serious cases of human trafficking and how traffickers, their victims, and consumers (the demand) overlap and interact across locations. This study examines known human trafficking enterprises for which sufficient evidence has been obtained to result in prosecution. These are also serious cases because US federal and international prosecutions result when the offenses are interstate or international in scope. Using a sample of US cases prosecuted over three calendar years (2021-2024), combined with an international sample of cases, an effort is made to develop …

Sex Buying, Sex Trafficking, And Organized Crime: Introduction To A Special Issue, Marcel Van Der Watt, John A. Winterdyk

Dignity: A Journal of Analysis of Exploitation and Violence

No abstract provided.

Disrupting Transnational Human Trafficking Networks: A Practitioner's Perspective On Intelligence-Driven, Offender-Focused Strategies, Rochelle Keyhan

Dignity: A Journal of Analysis of Exploitation and Violence

This article examines human trafficking through the lens of organized crime and explores how this perspective can be applied to contemporary trafficking cases in the United States. While trafficking is often prosecuted as an isolated criminal act, many incidents are linked to larger transnational and domestic organized crime networks. The discussion highlights the activities of notorious syndicates, including international cartels, street gangs, and well-funded networks of sex buyers, demonstrating how these entities exploit vulnerable populations for profit. Reframing human trafficking as a sector within organized crime shifts investigative and prosecutorial strategies away from victim-dependent models, which often require survivors to …

A Thickness-Invariant Origami Robot With Integrated Actuation And Multimodel Locomotion, Larry L. Howell, Davis Wing, Nathan Usevitch, Sam Bridge, William Bowler

Faculty Publications

ABSTRACT Origami robots possess the potential for advanced reconfigurability in various contexts and environments. This paper describes and demonstrates the function of an origami robot following a thickness-invariant version of the Yoshimura tessellation. This thickness-invariance allows for the simple folding pattern to be expanded vertically, allowing all robotics components to be housed within the panels of the robot without impacting the functional relationships between folds of the pattern, or requiring other, more complex forms of thickness accommodation. The mathematics and engineering to create such a robot are presented to enable the use of these techniques in creating other origami-based robots. …

Polyphenol Diet And Exercise As Neuroprotection From Effects Of Alzheimer's Disease, Michelle Morgan

Loma Linda University Electronic Theses, Dissertations & Projects

Healthy non-pharmacological lifestyle factors, such as regular physical exercise and a dietary supplementation, have been shown to significantly improve cognitive outcomes over time compared to a more sedentary lifestyle and poor diet. Furthermore, exercise may serve as a potential protective factor in attenuating the effects associated with cognitive decline that are characteristic of neurodegenerative disorders, such as Alzheimer's disease (AD). Further, evidence indicates that certain diet interventions can also attenuate the effects of neurodegeneration and positively impact longevity. Supplementation of polyphenols, such as ellagic acid (EA), which are abundant in pomegranate juice, may help provide neuroprotective benefits and elicit a …

Comparison Of Lower-Extremity Coordination Patterns During Countermovement Jumps Between Dancers And Nondancers, Danielle Joseph

Honors Theses

Jumping is a skill essential to several different sports, including dance. For athletes in jump-dominant sports, jump strategies can vary with differences in task demands while jump performances are similar. The countermovement jump (CMJ) has been utilized to analyze jumps because of their reliable indications of power and neuromuscular function. Methods of describing jump strategies using CMJ, such as force plate metrics, vector coding analysis, and coordination phases, have been used to describe the jumps of athletes in jump dominant sports such as basketball and volleyball. However, less jump strategy research has been done on dancers, especially to describe the …

A Systematized Review Of Parent Experiences With Special Education Placement In Rural Communities, Madeline Bishop

Educational Specialist, 2020-current

Parents of children enrolled in special education programs often face unique challenges, particularly in rural settings where access to resources and communication with school personnel can be limited. This systematized review explores how rural school systems can best support parents during the special education process. A systematized review of articles published between 2005 and 2025 was conducted. A thematic analysis of 20 articles revealed 3 themes following the review: benefits and barriers to rural special education, professional relationships, and parents’ strain and appreciation. Overall findings highlight the importance of the experiences between parents and school personnel regarding special education. Limited …

Finding Balance: School-Based Yoga Interventions And Their Alignment Within Multi-Tiered Systems Of Support, Ursula Vogt

Educational Specialist, 2020-current

School-based interventions that support emotional regulation and student well-being are increasingly emphasized within Multi-Tiered Systems of Support (MTSS). Yoga has emerged as a potential school-based practice; however, its outcomes, alignment with MTSS frameworks, and implementation characteristics remain unclear. This systematized review examined (a) psychological, emotional, and behavioral outcomes associated with school-based yoga interventions, (b) their alignment with Tier 1 and Tier 2 supports, and (c) implementation characteristics that support feasibility in school settings. A systematic search identified 21 U.S.-based studies, which were analyzed using thematic analysis. Findings indicated that yoga interventions were associated with improvements in emotional regulation, stress and …

Supporting Every Student: Optimizing School-Based Mental Health Services For Students With Intellectual Disabilities, Sarah K. Eggleston

Educational Specialist, 2020-current

Youth with intellectual disabilities (ID) are at considerably greater risk of developing mental health problems compared with the general population; however, their needs are less likely to be identified, and they often face barriers to accessing quality mental health care. School-based mental health professionals (SBMHPs) are uniquely positioned to support students within their natural learning environments, where many common barriers to service provision have been removed. The present study examined the current state of practice among SBMHPs in Virginia in identifying and supporting the needs of students with ID, as well as SBMHPs’ training experiences. An online cross-sectional, mixed-methods survey …

Students With Borderline Intellectual Functioning: Dropping The Label And Reducing The ‘Line’, Samantha M. Sitzman

Educational Specialist, 2020-current

Students with Borderline Intellectual Functioning (BIF) often experience significant academic and social-emotional difficulties while remaining ineligible for many formal special education services, creating challenges in identifying and supporting this population within school settings. This convergent mixed methods study examined school psychologists’ perspectives regarding the challenges experienced by students with BIF, the interventions commonly used to support them, and the systemic barriers associated with service delivery. Twenty-two practicing school psychologists in Virginia completed a researcher-developed survey containing quantitative and qualitative items. Quantitative data were analyzed using descriptive statistics, and qualitative responses were analyzed using thematic analysis.

Findings indicated that school psychologists …

Cellular Senescence Links Muscle Atrophy And Posttraumatic Osteoarthritis After Acl Injury, Alexander R. Keeble, Allison Owen, Sara Gonzalez-Velez, Nicholas T. Thomas, Camille R. Brightwell, Peyton J. Balawender, Madeline G. O'Daniel, Helena C. Weiss, Haley Noehren, Heather Thompson, Karen Sofia Zuluaga-Osorio, Zane T. Bates, Lauren Gottlieb, Douglas E. Long, Douglas Harrison, Philip Kern, Caitlin E. Conley, Michael A. Samaan, Stephen Duncan, Austin Stone, Darren Johnson, Yuan Wen, Brian Noehren, Cory Dungan, Christopher Fry

Biology Faculty Publications

Traumatic knee injury leads to posttraumatic osteoarthritis (PTOA) and significant skeletal muscle weakness, resulting in chronic disability. The current standard of care frequently fails to prevent musculoskeletal dysfunction, underscoring the need to identify therapeutic mechanisms of PTOA. Using an established preclinical anterior cruciate ligament (ACL) transection model of PTOA and leveraging an innovative SPiDER-senescence-associated β-galactosidase stain to discern senescent cells, we investigated cellular senescence at single-cell resolution and identified anti-inflammatory macrophages as a predominant contributor to the senescent cell burden in both muscle and knee joint after injury. Clearance of senescent cells using the senolytic dasatinib and quercetin (D + …

Chameleon Carriers In Trucking: Detection, Enforcement, And Financial And Safety Impacts, Brian Howell, Drew Law, Andrew Martin

Kentucky Transportation Center Research Report

Chameleon carriers are motor carriers that evade regulatory enforcement by dissolving and reregistering under new corporate identities. This study, commissioned by the Kentucky Transportation Cabinet (KYTC), examined how states characterize, detect, and respond to chameleon carrier activity and assessed its financial and safety impacts in Kentucky from 2020 through 2025. The research team conducted a literature review of existing agency practices and relevant stakeholder perspectives, reviewed administrative codes and statutes across 13 pilot states, and administered two structured surveys to state motor carrier credentialing officials examining carrier characterization and enforcement practices. An analysis of KYTC's carrier data flagged by CVIEW …

2025-26 Review, University Libraries

University Libraries Annual Report

This 2025-26 Review highlights the achievements, services, and collections of University Libraries at The University of Southern Mississippi. Explore the ways the Libraries support student success, teaching and research, preserve and share unique collections, and create opportunities for learning and discovery across the University and beyond.

A Mixed-Methods Study Of The Lived Experiences Of Patients And Caregivers Receiving Home Health Occupational Therapy Services, Peyton A. Mendias

Student Capstone Papers

Home health occupational therapy (OT) supports individuals’ safety, independence, and participation in their natural environments; however, patients and caregivers may face barriers that affect the implementation of therapy recommendations. This capstone project explored patient and caregiver experiences with home health OT and identified factors influencing implementation of OT recommendations. We used a sequential explanatory mixed-methods design guided by the Capability, Opportunity, Motivation–Behavior (COM-B) model. Eight participants, including three patients and five caregivers, completed an electronic survey, and one caregiver participated in a follow-up semi-structured interview. We analyzed quantitative data using descriptive statistics and qualitative data using reflexive thematic analysis. Findings …

Transgender And Gender-Diverse Healthcare Through Virtual Social Networking, Francis Peter Furmanek Iii

PhD of Social Work

This study examined the behavior of transgender and gender diverse (TGD) utilizing virtual social networking (VSN) to address their healthcare needs. Presently, the TGD community has been facing discrimination in policy and social structure across the United States. Accepting safe spaces are vital to survival and growth of TGD people, and the current wave of anti-trans legislation seeks to eliminate these spaces. This phenomenological mixed-methods study examined mechanisms that TGD people use to address healthcare needs in virtual spaces alongside a backdrop of negative healthcare experiences in traditional settings. Informed by Intersectional theory, Minority Stress Theory, and considering Andersen’s Behavioral …

Barriers To Access: Examining Nonprofit Service Delivery In Rural Communities, Elizabeth Knight

School of Professional and Continuing Studies Nonprofit Studies Capstone Projects

Around sixty-six million Americans live in rural communities; however, the research on what accessibility barriers exist for rural residents accessing nonprofit services is limited. Rural communities often face persistent barriers to accessing essential services, including transportation challenges, geographic isolation, and financial hardship. Nonprofit organizations employ strategies to respond to these barriers; however, organizational capacity constraints make it difficult for nonprofits to alter their service delivery strategies. This study uses semi-structured interviews with nonprofit leaders to identify what nonprofit accessibility barriers can currently be seen in rural Virginian communities. Findings also explore how nonprofits navigate these barriers and what they do …

Improving Obesity Management In Primary Care Through Provider Education, Natalie Anderson

Doctor of Nursing Practice Projects

Background: Childhood obesity is a significant public health concern associated with metabolic, cardiovascular, and psychosocial complications. Despite the availability of evidence-based pediatric obesity management guidelines, adherence to these guidelines remains inconsistent in primary care settings. Purpose: This evidence-based quality improvement project aimed to determine whether provider education on the 2023 American Academy of Pediatrics (AAP) Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity, combined with implementation of an electronic health record (EHR) clinical decision support prompt, improved provider knowledge and adherence to guideline-recommended obesity management practices. Method: A pre-post quasi-experimental study was …

Professor Greenfeld’S Last Class: Notes For Online Lectures On “The Science Of Humanity,” Delivered To Students And Scholars Primarily From India, July 2025, Liah Greenfeld

Comparative Civilizations Review

The question for this class is: What is humanity?

We all believe we all know what it is, don’t we? After all, there is hardly any subject more important for us, a question on the answer to which other subjects depend — political, social, economic. Answers to questions such as: what are human economic needs and desires; what political structures are optimal for humans; is democracy, for instance, a universal human desire; should politics in every nation be democratic, or, perhaps, authoritarian governments are better; is freedom a natural need, does it make life better, does equality?

Positive Curvature And Discrete Abelian Symmetry, Lee Kennard, Elahe Khalili Samani, Catherine Searle

Mathematics

By replacing the torus with an elementary abelian two-group, we generalize Grove and Searle’s maximal symmetry result and Wilking’s half-maximal symmetry result for positively curved manifolds with an isometric torus action. © The Author(s) 2026.

Crystal Structure Of New Polar Rare Earth Borates Na2.62Ln2.12(Bo3)3 (Ln = Pr, Nd, Sm) Containing Isolated Bo3 Groups, Alevtina A. Maksimova, Mark D. Smith, Hans Conrad Zur Loye

Faculty Publications

Three new rare earth borates, Na2.62Ln2.12(BO3)3 (Ln = Pr, Nd, Sm), were synthesized via a high-temperature solution reaction using a BaCO3–H3BO3–NaF flux and structurally characterized by single-crystal X-ray diffraction analysis. The compounds crystallize in the orthorhombic space group Amm2 with lattice parameters a = 5.0985(10) Å, b = 11.180(2) Å, c = 7.1483(14) Å, and a unit cell volume of 407.48(14) ų (Z = 2) for Na2.62Pr2.12(BO3)3, a = 5.0983(10) Å, b = 11.181(2) Å, c = 7.1491(14) Å, and a unit cell volume of 407.51(14) ų (Z = 2) for Na2.62Nd2.12(BO3)3, and a = 5.08630(10) Å, b …

A Stabilized Weighted Interior Penalty Method For Thermal Convection Model In Heterogeneous Porous Media, Yuanyuan Hou, Qianqian Ding, Xiaoming He, Yanping Lin

Mathematics and Statistics Faculty Research & Creative Works

In this article, we propose and analyze a stabilized weighted interior penalty method for solving the thermal convection problems in heterogeneous porous media. We first transform the thermal convection model into the pressure primal form with homogeneous Neumann boundary condition and develop a symmetric weighted interior penalty method to handle the discontinuous Darcy number and automatically adjust the penalty coefficient corresponding to the varying permeability. Then we recover the velocity by a stabilized method and incorporate it into the energy equation to obtain the temperature. The stability and convergence rates of the numerical solutions are rigorously proved and verified by …

Single Crystal Growth Of The Orthoborate Nabalu(Bo3)2 And Optical Investigation Of Eu3+ And Tb3+ Doped Nabalu(Bo3)2, Alevtina A. Maksimova, Mark D. Smith, Lakshani W. Masachchi, Hans Conrad Zur Loye

Faculty Publications

Sodium barium lutetium borate NaBaLu(BO₃)₂ crystals were synthesized using a high-temperature solution method. The crystal structure of this layered orthoborate is described and corresponds to that of an extensive orthoborates family, NaBaR(BO₃)₂ (R = Sc, Y, Yb, Tb – Lu). NaBaLu(BO₃)₂ was doped by Eu³⁺ and Tb³⁺ to explore its performance as a host material and to investigate the luminescent properties of the Eu³⁺ and Tb³⁺ doped materials. The emission spectra of the NaBaLu(BO₃)₂:Ln (Ln = Eu, Tb) crystals are presented. The most …

The True Scope Of Trusting Your Gut: A Study Into The Enteric Nervous System And The Relationship Between The Gut-Brain Axis And The Mind, Bryan Pham

Theses & ETDs

Since the early days of medicine, the “gut” had been associated as a seat of emotions and intuition, but as modern science marched forward, the brain itself was given complete dominion over mental health. But thanks to research into the enteric nervous system (ENS), which innervates the digestive tract and bilaterally communicates with the brain as a secondary function, we now know that, in a sense, the gut does indeed have a substantial impact on mental health outside of its primary functions. This profound discovery could potentially cause a massive rewrite for decades of modern neuroscience-based medicine. Overall, the study …

Thermal Conversion Of Cotton Gin Byproducts Into Liquid Fuels And High-Value Chemicals, Emmanuel Asare

Mechanical Engineering Theses

In this study, we performed fast pyrolysis, catalytic fast pyrolysis (CFP), and catalytic hydropyrolysis (CHP) of cotton gin byproducts (CGB) to investigate their conversion into hydrocarbon-rich liquid fuels and high-value aromatic chemicals. Five CGB fractions (CC1, CC2, SM, TM, and FCGB) were collected from different stages of cotton ginning operation and characterized by proximate, ultimate, and higher heating value (HHV) analysis. The feedstocks contained 41.5 44.8 wt.% carbon, 54.2–58.5 wt.% volatile matter, 6.0–15 wt.% ash, and higher heating values of 15.2–16.8 MJ kg⁻¹. All pyrolysis experiments were performed using a Pyroprobe 5200 coupled with GC-MS/FID, while catalyst loading, hydrogen pressure, …

Development And Validation Of A Multidimensional Measure Of Role Ambiguity: Integrating Nlp-Based Factor Analytic Techniques With Traditional Psychometrics, Md Allama Ikbal Sijan

Theses, Dissertations and Culminating Projects

This dissertation developed and validated the Multidimensional Role Ambiguity Scale (MRAS), a measure that separates role ambiguity into five subdimensions: goal/expectation/responsibility ambiguity, process ambiguity, priority ambiguity, behavior ambiguity, and performance criterion ambiguity. Although role ambiguity is one of the most studied role stressors in organizational research, it has been measured largely as a single global score, a practice that masks differences among its facets and may explain the inconsistent criterion relationships reported in prior work. Scale development followed the three-step framework of Singh and Rhoads (1991). Thirty items were generated from working definitions grounded in role theory, and fifteen research …

Temperature And Salinity Effects On The Physiology Of Bullfrog Tadpoles (Lithobates Catesbeianus) From A Suburban Temperate Wetland, Angela Brown

Theses, Dissertations and Culminating Projects

One of the most robust amphibians is the American Bullfrog, Lithobates catesbeianus, which is a widespread species that is invasive worldwide, and is broadly tolerant of a range of environmental conditions. Despite this tolerance, survival and performance of adult L. catesbeianus can be negatively affected by increasing temperatures and salinity resulting from anthropogenic impacts, such as climate change and road salts. This study focuses on the effects of acute salinity exposure (mimicking road salt influx into a pond) on L. catesbeianus tadpoles at different larval stages. Increased salinity was predicted to negatively affect two physiological performance measures. Critical maximum temperature …

A Comprehensive Study And Performance Optimization Of Shared Virtual Memory, Bennett Cooper

All Dissertations

High performance computing (HPC) is dominated by heterogeneous systems that mainly derive performance from GPU accelerators. A majority of HPC applications have gravitated towards GPUs, which require explicit programming. Historically, programming explicitly to take advantage of GPUs has proven a significant barrier in fully utilizing GPU acceleration. Unified Memory (UM) is a technology designed to lower the barrier of entry to GPU programming by merging all memory domains of a system. While UM provides easier access to the capabilities of heterogeneous systems, the performance cost of UM greatly detracts from the benefit. Additionally, UM is implemented on a vendor-by-vendor basis …

Exploring Optimal Indoor Environmental And Spatial Conditions In Virtual Reality: Implications For Human Experience And Productivity, Seonghyuk Son

All Dissertations

This dissertation investigates how indoor environmental and spatial design conditions influence human experience and productivity, focusing on thermal conditions, lighting conditions, and spatial configuration. Because people spend most of their time indoors, environmental design plays an important role in comfort, emotional well-being, and cognitive functioning. Although previous studies have shown that temperature, lighting, and architectural features influence human responses, many have examined these variables separately. In addition, relatively few studies have integrated perceptual, emotional, cognitive, and physiological outcomes within a single framework.

Study 1 examined the combined effects of indoor temperature, lighting intensity, and correlated color temperature on cognitive performance …

Explaining The Relationship Between Trust And Dependence: The Unexplored Interactive Effect Of Workload And Individual Differences In Cognitive Abilities, Connie Ku

All Dissertations

Trust is often treated as a key driver of automation use, with the assumption that higher trust leads to greater dependence. Yet findings have been inconsistent, with trust-dependence correlations ranging from negative to positive, and some studies finding no relationship at all. One factor that may explain this inconsistency is mental workload, which has received little attention as a moderator. This research examined whether workload moderates the trust-dependence relationship, and whether attention control, working memory, and fluid intelligence further shape this moderation.

Study 1 used a web-based AI chatbot quiz to test whether workload moderated the trust-dependence relationship. Trust was …