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Articles 71101 - 71130 of 1825045
Full-Text Articles in Entire DC Network
Are We Too Invested In Sports?, Joshua E. Hollinger
Are We Too Invested In Sports?, Joshua E. Hollinger
Faculty Work Comprehensive List
"What would it look like to rein in and re-orient our love of sports, such that it becomes part of our worship of the one true God?"
Posting about a balanced perspective on sports from In All Things, an online hub that offers insight into maintaining and faithful and orthodox Reformed Christian worldview while fearlessly engaging in every aspect of contemporary life – until all is made new.
Are We Too Invested in Sports?
2023-04-25 Executive Council Minutes, Susie Salazar
2023-04-25 Executive Council Minutes, Susie Salazar
Executive Council Minutes
No abstract provided.
Potential Of Legume Seeds From The Leguminosae Family As Material Source Of Food And Medicine : A Literature Review, Ni Made Ayu Gangga Dewi, Nina Dewi Oktaviyanti, Aurapa Sakulpanich, Kartini Kartini
Potential Of Legume Seeds From The Leguminosae Family As Material Source Of Food And Medicine : A Literature Review, Ni Made Ayu Gangga Dewi, Nina Dewi Oktaviyanti, Aurapa Sakulpanich, Kartini Kartini
Pharmaceutical Sciences and Research
Leguminosae, also known as Fabaceae, is the third largest plant family after Orchidaceae and Asteraceae. This review aimed to explore the potential of several legume species indigenous to Indonesia, from the Leguminosae family, as sources of food and medicine. The data used for the analysis were collected from various online databases such as PubMed, ScienceDirect, and Google Scholar. The results showed that there were 13 species of Leguminosae family plants found easily in Indonesia including Cajanus cajan, Canavalia ensiformis, Mucuna pruriens, Arachis hypogaea, Vigna subterranea, Glycine max, Phaseolus vulgaris, Phaseolus lunatus, Vigna radiata, Vigna unguiculata subsp. unguiculata, Vigna angularis, Vigna …
Optimization Of Formula, Stability Testing, And Antioxidant Activity Of Clay Masks As Skin Moisturizers, Naniek Widyaningrum, Agung Dwi Anggoro Bhakti, Alghafiqy Harya Evan Maulana, Amalia Safitri, Adinda Fajrah Ramadhani, Anisa Febriani, Anggit Naufal Hanafi, Thendi Abdul Arief
Optimization Of Formula, Stability Testing, And Antioxidant Activity Of Clay Masks As Skin Moisturizers, Naniek Widyaningrum, Agung Dwi Anggoro Bhakti, Alghafiqy Harya Evan Maulana, Amalia Safitri, Adinda Fajrah Ramadhani, Anisa Febriani, Anggit Naufal Hanafi, Thendi Abdul Arief
Pharmaceutical Sciences and Research
Clay masks are cosmetic formulations designed to adhere closely to the skin, effectively lifting contaminants, cleansing the face, and absorbing impurities. We made a clay mask containing active ingredients such as niacinamide, alpha arbutin, ceramide, and hyaluronic acid. A careful selection of ingredients is essential for ensuring safety and mitigating potential dermatological issues. This study aimed to evaluate the physical characteristics, stability, primary irritation potential, and moisturizing efficacy of this clay mask formulation. Kaolin and bentonite are the primary base materials. The research included formulation optimization and physical stability testing using a cycling test, where each cycle was conducted over …
Indian Cosmology And Archaeoastronomy Of The Khmer Stone Temples In Sakon Nakhon-Thailand, Duangden Boonpok
Indian Cosmology And Archaeoastronomy Of The Khmer Stone Temples In Sakon Nakhon-Thailand, Duangden Boonpok
International Review of Humanities Studies
This article is multidisciplinary study of cosmology, archaeology and astronomy of the Khmer stone temples in Sakon Nakhon. The study investigates of the temple’s architectural structure and environmental geography which related to the astronomical knowledge. The result of study found that the plan and structure of temples is influenced by the concept of Indian cosmology which has Mount Meru as the central axis. Buildings is signified as mountain or heaven with high and multi-layered base. The main building is symbolically important as the origin of power for the whole temple. The objects and positions are the transforming of cosmology concept …
The Influence Of The Dutch East Indies Government’S Ethnic Politics On Discrimination Against The Chinese Ethnic Group In Batavia (1946–1950), Zaky Rizqy Zaidaan Fadrin, Fajar Muhammad Muhammad Nugraha
The Influence Of The Dutch East Indies Government’S Ethnic Politics On Discrimination Against The Chinese Ethnic Group In Batavia (1946–1950), Zaky Rizqy Zaidaan Fadrin, Fajar Muhammad Muhammad Nugraha
International Review of Humanities Studies
This study explains how discrimination was experienced by ethnic Chinese in Batavia in the early post-independence period in 1946–1950, with an emphasis on the influence of ethnic politics practiced by the Dutch East Indies colonial government. The purpose of this study is to analyze the pattern of discrimination against ethnic Chinese influenced by the legacy of colonial racial segregation. The method used is qualitative historical descriptive. The main sources of this study come from letters of complaint from the Chinese community in 1946–1949 in the National Archives of the Republic of Indonesia (ANRI) and newspaper articles from 1950 from De …
The Comparison Of Classical Tafsir And Contemporary Interpretation Regarding The Verses Of Astrophysics And Cosmology In The Qur’An, Azra Ansharullah, Basuni Imamuddin
The Comparison Of Classical Tafsir And Contemporary Interpretation Regarding The Verses Of Astrophysics And Cosmology In The Qur’An, Azra Ansharullah, Basuni Imamuddin
International Review of Humanities Studies
As time progressed, various kinds of discoveries in the field of science emerged one by one, especially in the field of Astronomy and its "little brother" Astrophysics. This opens up opportunities for everyone to research things that have been researched from a new perspective, such as researching the Koran from a science and technology perspective. There are 310 instances in the Qur'an where the word "heaven" is mentioned, and within them, there are various statements regarding the nature, phenomena, and other things related to the sky. With the progress of technology, there is undoubtedly a gap in the interpretation and …
The British Colonial Land Policy And The Development Of Plantation Agriculture In Colonial Southwestern Nigeria, Adesola S. Adesote
The British Colonial Land Policy And The Development Of Plantation Agriculture In Colonial Southwestern Nigeria, Adesola S. Adesote
International Review of Humanities Studies
The main thrust of this paper is to critically analyse the impact of the colonial land policy of the British on plantation agriculture in colonial Southwestern Nigeria. Although land legislation had been introduced as far back as the late 19th century, such as the Public Lands Ordinance of 1876 later renamed the Public Lands Acquisition Ordinance of 1917, it was vigorously pursued with the imposition of colonial rule in the period between 1900 and 1960. It argued that the introduction of land policy by the British in order to achieve her economic objective in Nigeria led to the commercialisation …
Investigating The Determinants Of Influenza Entry And Spread In Human Airway Cells Using Fluorescence Microscopy, Zijian Guo
McKelvey School of Engineering Graduate Student Theses & Dissertations
Influenza A virus (IAV) remains a significant global health challenge. IAV utilizes the receptor binding protein hemagglutinin (HA) and the receptor destroying protein neuraminidase (NA) to facilitate infection. The activities of these proteins affect multiple steps in IAV life cycle. However, it remains unclear how these IAV factors influence infection dynamics in the context of a complex cellular environment encountered in the respiratory tract. In this work, we use fluorescence microscopy and human airway epithelial cells to study influenza biology at the single-cell and single-virion level, revealing key insights into viral binding, entry, and spread. First, we focused on the …
Effective Strategies That Marketing Leaders Use To Increase Fan Base, Denise Leslie Rosa
Effective Strategies That Marketing Leaders Use To Increase Fan Base, Denise Leslie Rosa
Walden Dissertations and Doctoral Studies
Despite its growth and potential, the Women’s National Basketball Association (WNBA) consistently struggles to generate profit, remaining unprofitable in its 28th (2024) season and heading into its 29th (2025) season. The inability of women’s professional basketball marketing leaders to generate increased revenue and fan engagement has limited the sport’s growth and visibility. Grounded in McCarthy’s four Ps of marketing concept that includes product, price, place, and promotion, the purpose of the qualitative pragmatic inquiry project was to identify and explore effective and innovative marketing strategies that marketing leaders use to increase the revenue of women’s professional basketball teams and their …
Neighborhood Environment And Incident Diabetes, A Neighborhood Environment-Wide Association Study ('Ne-Was'): Results From The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol)., Cara M. Smith, Elizabeth W. Spalt, Linda C. Gallo, Jordan A. Carlson, Matthew Allison, Daniela Sotres-Alvarez, Christina Cordero, Qibin Qi, Earle C. Chambers, Martha Daviglus, Amber Pirzada, Gregory A. Talavera, Robert Kaplan, Joel D. Kaufman, Stephen J. Mooney
Neighborhood Environment And Incident Diabetes, A Neighborhood Environment-Wide Association Study ('Ne-Was'): Results From The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol)., Cara M. Smith, Elizabeth W. Spalt, Linda C. Gallo, Jordan A. Carlson, Matthew Allison, Daniela Sotres-Alvarez, Christina Cordero, Qibin Qi, Earle C. Chambers, Martha Daviglus, Amber Pirzada, Gregory A. Talavera, Robert Kaplan, Joel D. Kaufman, Stephen J. Mooney
Manuscripts, Articles, Book Chapters and Other Papers
The prevalence of type 2 diabetes is increasing among the Hispanic/Latino population. Type 2 diabetes incidence rates vary between neighborhoods, but no single aspect of the neighborhood environment is known to cause type 2 diabetes. Using data from the Hispanic Community Health Study/Study of Latinos cohort of 16,415 Hispanic/Latino adults in four major US cities, we conducted a neighborhood environment-wide association study to identify neighborhood measures or clusters of measures associated with diabetes incidence. Two-hundred and four neighborhood measures were calculated at the census tract level or within a 1-km buffer of participants' residential addresses. Independent covariate-adjusted and survey-weighted Poisson …
Network Intelligence For Next-Generation Wireless Networks: Advancing Distribution And Coordination, Yonatan Melese Worku
Network Intelligence For Next-Generation Wireless Networks: Advancing Distribution And Coordination, Yonatan Melese Worku
Electrical and Computer Engineering ETDs
Next-generation wireless networks, encompassing 6G and beyond, face rigorous demands for ultra-low latency, ubiquitous connectivity, exceptionally high data rates, and robust security, necessitating innovative approaches to resource optimization and network protection. This dissertation proposes a pioneering framework that synergizes advanced methodologies—deep reinforcement learning, deep learning, blockchain, and multi-agent systems—to address these challenges. Distributed architectures, underpinned by AI-driven multi-agent systems, form the backbone of this framework, enabling seamless integration and intelligent orchestration across diverse domains. The research advances IoT-based systems leveraging machine learning for resource efficiency in healthcare applications, develops reinforcement learning-driven frameworks to optimize energy and coverage for Unmanned Aerial …
Finite Element Investigation Of Blast Load Responses In Nuclear Power Plant Containment Structures, Janak Raj Awasthi
Finite Element Investigation Of Blast Load Responses In Nuclear Power Plant Containment Structures, Janak Raj Awasthi
Civil Engineering ETDs
Some significant incidents like the Chernobyl disaster (1986), the Fukushima Daiichi hydrogen explosion (2011), and some frequent military and terror threats to the nuclear Power plant structures have led to studying the capacity of power plant structures to withstand blast loadings. From this research, even one-third of the loss of the coolant is enough to damage the power plant structure. Crack starts from the wall and propagates toward the top of the dome and the foundation. The external blast shows high damage symptoms near the foundation area. Most of the steel members, including the rebars, Liner, and Tendons, showed high …
From Backstage To Front Stage : Understanding Dramaturgical Work Behavior In The Workplace, Yufei Cheng
From Backstage To Front Stage : Understanding Dramaturgical Work Behavior In The Workplace, Yufei Cheng
Lingnan Theses (MPhil & PhD)
Modern organizations often reward “looking busy” rather than genuinely contributing, prompting employees to engage in superficial displays of productivity. This type of behavior can be considered as a previously unexplored yet important form of impression management. While impression management research has predominantly examined outcome-oriented tactics, it has not fully captured the subtler, non-contributory forms of performative behavior that permeate everyday work life. To address this gap, this dissertation introduces Dramaturgical Work Behavior (DWB), a concept grounded in Goffman’ s dramaturgical theory, which outlines how employees enact symbolic “front-stage” performances—such as feigned urgency or exaggerated busyness—to signal conformity without adding real …
But Who Is It For? Introducing A Framework For Critical Reflection On Design And Delivery Of Ethical Participatory Research, Hannah Gardiner, Clare Pettinger, Louise Hunt, Mary Hickson
But Who Is It For? Introducing A Framework For Critical Reflection On Design And Delivery Of Ethical Participatory Research, Hannah Gardiner, Clare Pettinger, Louise Hunt, Mary Hickson
School of Health Professions
Delivering ethical collaborative research is challenging, requiring disruption of assumptions, academic norms, and ways of working–including long-standing power dynamics. This article proposes a framework to support critical reflection on participatory practice; an adaptation of the wheel of consent. The adapted ‘ILBR’ framework explores the balance of who Initiates (makes requests/offers), does Labour (the action), gets Benefits, and takes on Risks (ILBR) in the conduct of research. This aims to support reflexive design and delivery of ethical participation, including a shift towards consent becoming an ongoing multi-way negotiation of agreements. Particularly it aims to support ‘interpersonal reflexivity’, and navigation of the …
Lifestyle Factors Contributing To Occupational Heat-Related Acute Kidney Injury, Jonathan Specht, Fabiano Amorim, Flavio De Castro Magalhaes, Zachary Mckenna, Zachary Schlader
Lifestyle Factors Contributing To Occupational Heat-Related Acute Kidney Injury, Jonathan Specht, Fabiano Amorim, Flavio De Castro Magalhaes, Zachary Mckenna, Zachary Schlader
Health, Exercise, and Sports Sciences ETDs
Workers worldwide are at risk for acute kidney injury due to hyperthermia and dehydration as a consequence of exertional heat stress. Limited research has explored the impact which lifestyle agents such as beverages, recreational drugs, and medications have on core temperature, hydration, and risk of acute kidney injury during physical work in the heat. To address this research gap, we explored the impact of three agents frequently used by construction workers on thermoregulation and markers of risk of acute kidney injury. First, we investigated the effect which ibuprofen ingestion has prior to one hour of running in the heat on …
Assessing The Ecological Drivers And Consequences Of Partial Migration In Hudson River Striped Bass Over Three Decades, Caitlin Egan Zimmer
Assessing The Ecological Drivers And Consequences Of Partial Migration In Hudson River Striped Bass Over Three Decades, Caitlin Egan Zimmer
Biology ETDs
Climate change and shifts in human land use have caused extensive impacts to the connectivity, structure, and resilience of aquatic populations. Partial migration (PM), where only some individuals from a population migrate while the rest remain resident, can mitigate population-level responses to environmental stressors. However, little is known of the underlying mechanisms promoting variation in migration and whether these shift over time. In the Hudson River Estuary, striped bass (Morone saxatilis) are known to exhibit anadromous PM behavior. Here, I measured carbon isotopes (δ13C) of essential amino acids in striped bass scales to determine variation in …
The Island Biogeography Of Mangrove-Dwelling Vertebrates: Isolation, Specialisation, And Extinction, Jian Xiong David Tan
The Island Biogeography Of Mangrove-Dwelling Vertebrates: Isolation, Specialisation, And Extinction, Jian Xiong David Tan
Biology ETDs
Mangroves are highly dynamic ecosystems that are widely distributed across the coastlines of the tropics and subtropics. Despite their low plant diversity, mangroves host a disproportionately high number of terrestrial vertebrate taxa. However, mangrove specialists — taxa that only occur in mangrove habitats — exhibit a global distribution that is incongruous with the broader background distribution patterns of mangrove-associated fauna, exhibiting higher diversity in Australia and Southeast Asia. This dissertation therefore aims to assess how the diversity and distribution of mangrove specialist fauna may have been shaped by the historical biogeography of mangroves, and the effects of mangrove specialisation on …
Plant Reproductive Strategies Shift In Response To Restoration Using Beaver Dam Analogs, Laurel F. Martinez
Plant Reproductive Strategies Shift In Response To Restoration Using Beaver Dam Analogs, Laurel F. Martinez
Biology ETDs
As riparian communities become increasingly degraded, restoration treatments are being implemented in streams to recover ecosystem functions. In the Jemez Mountains, beaver dam analogs (BDAs) are used to restore degraded streams by connecting the floodplain and increasing the extent of anoxic soil conditions. These environmental disturbances are expected to alter how riparian plants recruit, particularly their allocation to seed-based and vegetative regeneration strategies. We investigated whether BDAs and associated changes in soil water filled pore space (WFPS) affected riparian plant recruitment. We investigated the number of flowering stems as a proxy for seed-based regeneration and rhizome length and mass as …
Predicting Leakage From Nuclear Material Containers At Los Alamos National Laboratory Through Drop Testing, Leak Testing, Finite Element Analysis And Digital Image Correlation, Jude M. Oka, Yu-Lin Shen, Osman Anderoglu, Pankaj Kumar, Rajendra Vaidya
Predicting Leakage From Nuclear Material Containers At Los Alamos National Laboratory Through Drop Testing, Leak Testing, Finite Element Analysis And Digital Image Correlation, Jude M. Oka, Yu-Lin Shen, Osman Anderoglu, Pankaj Kumar, Rajendra Vaidya
Mechanical Engineering ETDs
Los Alamos National Laboratory (LANL) relies on containment vessels to safely manage special nuclear material. These containers are subject to rigorous testing—such as drop, fire, and water ingress testing—to ensure integrity under adverse conditions. While elastomer-based seals are well studied, metal-to-metal sealing mechanisms remain under investigation, particularly under dynamic loading. This research focuses on the relationship between container mating surfaces and impact loading through drop testing. Finite Element Analysis (FEA) models were developed and validated using Digital Image Correlation (DIC) to measure strain during impact. Drop tests at varying heights showed strong correlation between FEA and DIC results, confirming the …
Networked Systems: Synchronization, Decomposition And Transient Dynamics, Amirhossein Nazerian
Networked Systems: Synchronization, Decomposition And Transient Dynamics, Amirhossein Nazerian
Mechanical Engineering ETDs
This dissertation investigates synchronization, transient dynamics, control, and signal amplification in networked dynamical systems. First, it examines complete and cluster synchronization, including cases with large parametric mismatches, in both natural (e.g., brain networks, fireflies) and technological systems (e.g., power grids, robotics). Second, it studies transient dynamics in consensus processes, designing synchronization strategies that link reactivity, contraction theory, and Lyapunov exponents. Third, it addresses the computational limits of Model Predictive Control (MPC) for large networks by introducing an algebraic decomposition method that enables parallel online computation of smaller subproblems, enhancing MPC performance under hardware constraints. Finally, it analyzes the structural role …
Instability Analysis In Cylindrical Thin Film–Compliant Core Structures: Numerical Simulations And Effects Of Inelastic Deformation, Md Al Rifat Anan
Instability Analysis In Cylindrical Thin Film–Compliant Core Structures: Numerical Simulations And Effects Of Inelastic Deformation, Md Al Rifat Anan
Mechanical Engineering ETDs
When a thin film bonded to a thick compliant substrate is subject to in-plane compression, wrinkles can develop if the critical state for instability is reached. In various applications the film/substrate system may also take the form of cylindrical fibers, where an axial compressive loading can trigger axisymmetric wrinkles. A straightforward computational approach to simulate such wrinkling behavior is needed for material design, to either prevent wrinkling or to exploit its benefits for flexible device applications. In this work a comprehensive numerical study is undertaken by employing the finite element method. The embedded imperfection approach used previously for planar structures …
Multiscale And Multi-Model Studies Of Metal Plasticity, Luo Li
Multiscale And Multi-Model Studies Of Metal Plasticity, Luo Li
Mechanical Engineering ETDs
Plastic deformation is the process in which the material deforms permanently due to external effects. Twinning and slip are two main mechanisms of plastic deformation in metallic materials. The prominent mechanism of plastic deformation in metals that have FCC crystal structures is slip or gliding movement of dislocations, which is mainly focused on here. In the current study, frameworks for investigating plasticity phenomena of metals at different scales ranging from microscale to macroscale are demonstrated. Specifically, the macroscale modeling of plastic response of metallic materials induced by indentations are emulated by nonlinear FEA simulations. Simulation results of macroscale modeling are …
Phase Nanoscopy With Correlated Frequency Combs, Xiaobing Zhu
Phase Nanoscopy With Correlated Frequency Combs, Xiaobing Zhu
Optical Science and Engineering ETDs
In this dissertation a sensing method applying to any physical quantity that modifies optical phase is developed. Two pulses are produced inside a synchronously pumped Optical Parametric Oscillator, generating two identical, undistinguishable frequency combs. The physical quantity to be measured applies a small phase shift/round trip to one of the pulses, resulting in a frequency shift of the corresponding comb. The latter frequency is measured as a beat by interfering the two combs on a detector. A world record resolution, close to the quantum limit, of 0.033 nanoradian (corresponding to 0.006 fm in displacement) is achieved. A detailed analysis of …
Advancing Diamond Quantum Sensors: Isotropic Flux Concentrators And Phase Noise Mitigation, Maziar Saleh Ziabari
Advancing Diamond Quantum Sensors: Isotropic Flux Concentrators And Phase Noise Mitigation, Maziar Saleh Ziabari
Optical Science and Engineering ETDs
Two methods for improving the sensitivity of nitrogen vacancy quantum sensors in diamond are explored. First, by passively concentrating the magnetic flux, three orthogonally oriented ferrite truncated cone pairs amplify the field isotropically by 19 times, allowing measurement of Earth's field without a bias field and increasing sensitivity. Through thorough analysis, modeling and tuning a novel 3-dimensional flux concentrator system, we achieve a fractional standard deviation of less than 1% anisotropy and quantify minimal deadzones and ambient temperature-limited variations below 40 nT/hour. Second, we characterize, model and calculate phase noise in NV experiments, which in NV sensors is effectively indistinguishable …
A Systematic Approach To The Characterization Of Liquid-Vapor Coexistence In Platinum, Meghan K. Lentz
A Systematic Approach To The Characterization Of Liquid-Vapor Coexistence In Platinum, Meghan K. Lentz
Physics & Astronomy ETDs
Platinum is a material standard used in high pressure and shock compression experiments at Sandia National Laboratories. During experiments, materials are subjected to a very large range of thermodynamic conditions, during which materials regularly enter the liquid-vapor coexistence region. Despite its status as a standard, the region around the liquid-vapor critical point is poorly understood for platinum, with reported critical temperatures spanning approximately 7000 K. In this dissertation we conduct density functional theory based molecular dynamics (DFTMD) simulations for platinum for a range of temperatures and densities near liquid-vapor coexistence. The phase diagram for platinum is refined near the critical …
Understanding The Metallic And Oxide Phases In Platinum-Based Bimetallic Heterogeneous Catalysts After High-Temperature Oxidation, Stephen John Porter Jr
Understanding The Metallic And Oxide Phases In Platinum-Based Bimetallic Heterogeneous Catalysts After High-Temperature Oxidation, Stephen John Porter Jr
Nanoscience and Microsystems ETDs
Platinum (Pt) and palladium (Pd) are critical components in diesel emission control systems, enabling the conversion of harmful pollutants under demanding conditions. However, Pt’s effectiveness is hindered by sintering under high-temperature oxidizing environments. This dissertation investigates how Pt and Pd evolve under oxidizing conditions at 800°C, highlighting their distinct thermodynamic behaviors and interactions. Using TEM, EDS, EELS, XRF, XRD, and EXAFS, we show that Pd suppresses Pt sintering by reducing the volatility of PtO₂, leading to the formation of stable particles. Both Pt and Pd are present in metallic and oxide states, forming biphasic 'Janus' particles with conjoined metal and …
Using Triple Oxygen Isotopes To Investigate Water Usage In Desert Ecosystems, Cloe V. Knutson
Using Triple Oxygen Isotopes To Investigate Water Usage In Desert Ecosystems, Cloe V. Knutson
Earth and Planetary Sciences ETDs
In arid environments, maintaining water balance can be more critical for survival than obtaining food. As droughts intensify, understanding how animals manage body water is essential. Triple oxygen isotope analysis provides a novel way to trace water sources in animals, distinguishing contributions from free water, food-derived oxygen, and atmospheric O2. We developed an equilibration method using CO2–H2O oxygen exchange and measured δ’18O and Δ’17O values via tunable infrared laser direct spectroscopy (TILDAS). Validated against traditional fluorination methods, this technique enables streamlined analysis of whole blood and plant samples. Applied to …
Modeling Mars Chaos Terrains As Fracture Mosaics, Aidan C. Buie
Modeling Mars Chaos Terrains As Fracture Mosaics, Aidan C. Buie
Earth and Planetary Sciences ETDs
Chaos terrain exists on several planetary bodies but most notably on Mars. With 30 different named terrains and hundreds of chaotic or ”chaos-like” terrains, they are one of the most prominent and visible features on the planet. Chaos terrains have many visible similarities to each other: they all are comprised of polygonal blocks separated by fractures or channels. These blocks vary from angular to rounded and from flat plateaus to small hills, and the fractures vary from flat floored to ”v” shaped. Often, a single chaos will contain all of these morphologies. Most of the 30 named chaoses on Mars …
A Mutational Analysis Of Thatisin: How Single Point Mutations Impact The Biosynthetic Process Of A Group 16 Graspetide, John F. Boynton Jr
A Mutational Analysis Of Thatisin: How Single Point Mutations Impact The Biosynthetic Process Of A Group 16 Graspetide, John F. Boynton Jr
Chemistry and Chemical Biology ETDs
Abstract:
Graspetides are a family of Ribosomally synthesized and Post-translationally modified Peptide (RiPP) natural products named for their ATP Grasp Macrocyclases. We identified several Graspetide Biosynthetic Gene Clusters containing common double glycine cleavage motifs and attempted characterization of the mature Graspetides. One of the resulting peptides, Thatisin, has a topology with two interlocking macrolactones installed by a single ATP Grasp Ligase named ThtC. Here we use single and double point mutations to observe the impact or variation on the installation of these macrocycles. Alanine scan mutagenesis is used to assess leader peptide residues in the precursor peptide ThtA to determine …